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https://www.readbyqxmd.com/read/29073746/monoamine-oxidase-a-genetic-variants-and-childhood-abuse-predict-impulsiveness-in-borderline-personality-disorder
#1
Nathan J Kolla, Jeffrey Meyer, Marcos Sanches, James Charbonneau
Objective: Impulsivity is a core feature of borderline personality disorder (BPD) and antisocial personality disorder (ASPD) that likely arises from combined genetic and environmental influences. The interaction of the low activity variant of the monoamine oxidase-A (MAOA-L) gene and early childhood adversity has been shown to predict aggression in clinical and non-clinical populations. Although impulsivity is a risk factor for aggression in BPD and ASPD, little research has investigated potential gene-environment (G×E) influences impacting its expression in these conditions...
November 30, 2017: Clinical Psychopharmacology and Neuroscience: the Official Scientific Journal of the Korean College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29039227/the-violent-accounts-of-men-diagnosed-with-comorbid-antisocial-and-borderline-personality-disorders
#2
Craig Falcus, Darren Johnson
This study explored the violent offence accounts of life-sentenced prisoners diagnosed with comorbid antisocial personality disorder (ASPD) and borderline personality disorder (BPD). The aim of the current study was to gain needed clinical insight into the mechanisms involved in this specific group offenders' use of violence against others. Six adult male personality-disordered offenders were interviewed via a semistructured interview schedule to collate individual offence accounts. Interview transcripts were analyzed by the lead researcher (first author) using interpretative phenomenological analysis (IPA) who compared and contrasted findings to develop superordinate themes across the group...
October 1, 2017: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/28972814/examining-the-incremental-utility-of-dsm-5-section-iii-traits-and-impairment-in-relation-to-traditional-personality-disorder-scores-in-a-female-correctional-sample
#3
Chelsea E Sleep, Dustin B Wygant, Joshua D Miller
Personality disorders (PDs) are challenging to assess and are associated with great individual and societal costs. In response to the limitations of categorical models, the DSM-5 included an alternative model (i.e., Section III), which uses impairment (Criterion A) and pathological traits (Criterion B) to diagnose PDs. Although numerous studies have illustrated dimensional trait models' ability to capture personality psychopathology, less attention has been paid to personality impairment. The present investigation sought to examine Criterion A's ability to contribute incrementally to the prediction of antisocial (ASPD), borderline (BPD), and narcissistic personality disorders (NPD), and Interpersonal-Affective (F1) and Impulsive-Antisocial (F2) features of psychopathy...
October 3, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/28954596/antisocial-personality-disorder-in-older-adults-a-critical-review
#4
Katherine J Holzer, Michael G Vaughn
Antisocial personality disorder (ASPD) has enormous negative impacts on the affected individuals, their loved ones, and society. This burden is intensified by the social and functional changes related to age. The lower prevalence of ASPD in older adults compared to younger adults is well-documented. This discrepancy, often attributed solely to antisocial "burnout," contributes to the lack of attention given to this disorder in older adults and may signify difficulty measuring ASPD in this population. These measurement issues likely stem from problems with the validity of the diagnostic criteria for older adults which may not effectively capture changes that occur with age...
January 1, 2017: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/28931697/worldwide-experiences-with-assisted-peritoneal-dialysis
#5
REVIEW
Anna Giuliani, Akash Nayak Karopadi, Mario Prieto-Velasco, Sabrina Milan Manani, Carlo Crepaldi, Claudio Ronco
End-stage renal disease (ESRD) is common in the elderly population, and renal replacement therapy (RRT) is often required. However, in this particular subgroup of patients, the choice between hemodialysis (HD) and peritoneal dialysis (PD) is often not an easy decision to make. Published literature has adequately demonstrated that PD prevalence is significantly less than HD across all patient age groups despite several advantages. We also know that elderly patients are less likely to complete a PD assessment, due to both medical and social barriers...
September 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/28865940/oxytocin-improves-facial-emotion-recognition-in-young-adults-with-antisocial-personality-disorder
#6
Marion Timmermann, Haang Jeung, Ruth Schmitt, Sabrina Boll, Christine M Freitag, Katja Bertsch, Sabine C Herpertz
Deficient facial emotion recognition has been suggested to underlie aggression in individuals with antisocial personality disorder (ASPD). As the neuropeptide oxytocin (OT) has been shown to improve facial emotion recognition, it might also exert beneficial effects in individuals providing so much harm to the society. In a double-blind, randomized, placebo-controlled crossover trial, 22 individuals with ASPD and 29 healthy control (HC) subjects (matched for age, sex, intelligence, and education) were intranasally administered either OT (24 IU) or a placebo 45min before participating in an emotion classification paradigm with fearful, angry, and happy faces...
August 5, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28851912/association-of-monoamine-oxidase-a-genetic-variants-and-amygdala-morphology-in-violent-offenders-with-antisocial-personality-disorder-and-high-psychopathic-traits
#7
Nathan J Kolla, Raihaan Patel, Jeffrey H Meyer, M Mallar Chakravarty
Violent offending is elevated among individuals with antisocial personality disorder (ASPD) and high psychopathic traits (PP). Morphological abnormalities of the amygdala and orbitofrontal cortex (OFC) are present in violent offenders, which may relate to the violence enacted by ASPD + PP. Among healthy males, monoamine oxidase-A (MAO-A) genetic variants linked to low in vitro transcription (MAOA-L) are associated with structural abnormalities of the amygdala and OFC. However, it is currently unknown whether amygdala and OFC morphology in ASPD relate to MAO-A genetic polymorphisms...
August 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28810156/more-inflammation-but-less-brain-derived-neurotrophic-factor-in-antisocial-personality-disorder
#8
Tzu-Yun Wang, Sheng-Yu Lee, Ming-Chuan Hu, Shiou-Lan Chen, Yun-Hsuan Chang, Chun-Hsien Chu, Shih-Hsien Lin, Chia-Ling Li, Liang-Jen Wang, Po See Chen, Shih-Heng Chen, San-Yuan Huang, Nian-Sheng Tzeng, I Hui Lee, Kao Chin Chen, Yen Kuang Yang, Jau-Shyong Hong, Ru-Band Lu
Antisocial personality disorder (ASPD) is highly comorbid with substance use disorders (SUDs). We hypothesize that chronic neuroinflammation and the loss of neurotrophic factors prompts the pathogenesis of both disorders. We used ELISA to measure plasma levels of proinflammatory (tumor necrosis factor-α [TNF-α], C-reactive protein [CRP]) and anti-inflammatory factors (transforming growth factor-β1 [TGF-β1] and interleukin-10 [IL-10]), and brain-derived neurotrophic factor (BDNF) in male patients with ASPD (n=74), SUDs (n=168), ASPD comorbid with SUDs (ASPD+SUDs) (n=438), and Healthy Controls (HCs) (n=81)...
August 5, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28768209/borderline-personality-disorder-in-men-a-literature-review-and-illustrative-case-vignettes
#9
Adam Bayes, Gordon Parker
The aim is to review the salient literature on borderline personality disorder (BPD) in men and link those findings with case vignettes. We provide a literature review and then report case examples of those who met DSM and clinical BPD criteria, and consider the extent to which the small male sub-set corresponded developmentally and phenomenologically with prototypic BPD in women. The review considered phenomenological, epidemiological, biological and developmental BPD factors, finding BPD men evidence elevated substance abuse, and 'externalising' patterns of behavior, antisocial personality traits, violent self-harm and interpersonal aggression, whereas women display more 'internalising' strategies...
July 26, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28755613/dsm-5-cannabis-use-disorder-in-the-national-epidemiologic-survey-on-alcohol-and-related-conditions-iii-gender-specific-profiles
#10
Bradley T Kerridge, Roger Pickering, Patricia Chou, Tulshi D Saha, Deborah S Hasin
OBJECTIVE: The objective of this study was to present current information on the prevalence, correlates, comorbidity and quality of life among men and women with cannabis use disorder (CUD). METHODS: In 2012-2013, 36,309 respondents ≥18years old participated in face-to-face interviews in the National Epidemiologic Survey on Alcohol and Related Conditions-III. RESULTS: Prevalence of 12-month CUD was greater among men (3.5%) than women (1...
July 14, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28715261/social-media-use-and-conduct-problems-in-emerging-adults
#11
Victoria L Galica, Anna Vannucci, Kaitlin M Flannery, Christine McCauley Ohannessian
Social media use has become pervasive in the lives of emerging adults. Although social media may provide individuals with positive opportunities for communication and learning, social media sites also may provide an outlet for youth conduct problems, such as bullying, harassment, and intentional hostility and aggression toward others. Yet, the relationship between social media use and conduct problems remains unclear. This study investigated the association between conduct disorder (CD) symptoms before age 15 and social media use during emerging adulthood in a large, nationally representative sample...
July 2017: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/28557506/correction-to-chun-et-al-2017
#12
(no author information available yet)
Reports an error in "A psychometric investigation of gender differences and common processes across borderline and antisocial personality disorders" by Seokjoon Chun, Alexa Harris, Margely Carrion, Elizabeth Rojas, Stephen Stark, Carl Lejuez, William V. Lechner and Marina A. Bornovalova (Journal of Abnormal Psychology, 2017[Jan], Vol 126[1], 76-88). In the original record, there were two errors in the article's suppemental material. The supplemental material stated, "In each case, if the relaxed model fit significantly better than the baseline model (i...
May 29, 2017: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/28528231/neurocognitive-dysfunction-in-problem-gamblers-with-co-occurring-antisocial-personality-disorder
#13
Austin W Blum, Eric W Leppink, Jon E Grant
OBJECTIVES: Problem gamblers with symptoms of antisocial personality disorder (ASPD) may represent a distinct problem gambling subtype, but the neurocognitive profile of individuals affected by both disorders is poorly characterized. METHOD: Non-treatment-seeking young adults (18-29years) who gambled ≥5 times in the preceding year were recruited from the general community. Problem gamblers (defined as those meeting ≥1 DSM-5 diagnostic criteria for gambling disorder) with a lifetime history of ASPD (N=26) were identified using the Mini International Neuropsychiatric Interview (MINI) and compared with controls (N=266) using questionnaire-based impulsivity scales and objective computerized neuropsychological tasks...
July 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28426364/patterns-of-mood-and-personality-factors-and-associations-with-sti-hiv-related-drug-and-sex-risk-among-african-american-male-inmates
#14
Joy D Scheidell, Carl W Lejuez, Carol E Golin, Adaora A Adimora, David A Wohl, Larry D Keen, Michael Hammond, Selena Judon-Monk, Maria R Khan
BACKGROUND: Research on the association between antisocial personality disorder (ASPD) with comorbid mental disorders and sexually transmitted infection (STI)/HIV risk among inmates is scant despite the high prevalence of psychopathology and of STI/HIV in this population. METHODS: We used baseline data from Project DISRUPT, a cohort study conducted among incarcerated African American men (n = 207), to measure associations between ASPD and STI/HIV risk. We also conducted latent class analyses (LCAs) to identify subgroups defined by ASPD with comorbid stress, depression, and borderline personality disorder symptoms and measured associations between latent class membership and STI/HIV risk...
June 7, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28251591/impulsivity-and-cluster-b-personality-disorders
#15
REVIEW
Daniel Turner, Alexandra Sebastian, Oliver Tüscher
PURPOSE OF REVIEW: Impulsivity is a multifaceted construct and an important personality trait in various mental health conditions. Among personality disorders (PDs), especially cluster B PDs are affected. The aims of this review are to summarize the relevant findings of the past 3 years concerning impulsivity in cluster B PDs and to identify those subcomponents of self-reported impulsivity and experimentally measured impulse control that are most affected in these disorders. RECENT FINDINGS: All studies referred to antisocial (ASPD) or borderline PD (BPD), and none were found for narcissistic or histrionic PD...
March 2017: Current Psychiatry Reports
https://www.readbyqxmd.com/read/28223713/reduced-white-matter-integrity-in-antisocial-personality-disorder-a-diffusion-tensor-imaging-study
#16
Weixiong Jiang, Feng Shi, Huasheng Liu, Gang Li, Zhongxiang Ding, Hui Shen, Celina Shen, Seong-Whan Lee, Dewen Hu, Wei Wang, Dinggang Shen
Emerging neuroimaging research suggests that antisocial personality disorder (ASPD) may be linked to abnormal brain anatomy, but little is known about possible impairments of white matter microstructure in ASPD, as well as their relationship with impulsivity or risky behaviors. In this study, we systematically investigated white matter abnormalities of ASPD using diffusion tensor imaging (DTI) measures: fractional anisotropy (FA), axial diffusivity (AD), and radial diffusivity (RD). Then, we further investigated their correlations with the scores of impulsivity or risky behaviors...
February 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28196992/subtyping-of-alcohol-dependence-in-indian-males-a-cluster-analytic-approach
#17
Savita Malhotra, Debasish Basu, Abhishek Ghosh, Madhu Khullar, Neeraj Kakkar
OBJECTIVES: Two cluster solutions for the subtyping of alcohol dependence (AD) was investigated in an Indian male population. Subtypes were compared for various personality traits and childhood externalizing disorders. They were also compared with respect to single-nucleotide polymorphisms (SNP) of various candidate genes. MATERIALS AND METHODS: This was a clinic-based study conducted among 202 patients with AD. All patients were assessed with SSAGA-II for comorbid antisocial personality disorder (ASPD) and childhood conduct disorder (CD), oppositional defiant disorder (ODD), and attention deficit hyperactivity disorder (ADHD)...
October 2016: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28191653/generalized-hostile-interpretation-bias-regarding-facial-expressions-characteristic-of-pathological-aggressive-behavior
#18
Danique Smeijers, Mike Rinck, Erik Bulten, Thom van den Heuvel, Robbert-Jan Verkes
Individuals with aggression regulation disorders tend to attribute hostility to others in socially ambiguous situations. Previous research suggests that this "hostile attribution bias" is a powerful cause of aggression. Facial expressions form important cues in the appreciation of others' intentions. Furthermore, accurate processing of facial expressions is fundamental to normal socialization. However, research on interpretation biases in facial affect is limited. It is asserted that a hostile interpretation bias (HIB) is likely to be displayed by individuals with an antisocial (ASPD) and borderline personality disorder (BPD) and probably also with an intermittent explosive disorder (IED)...
February 12, 2017: Aggressive Behavior
https://www.readbyqxmd.com/read/28108863/genetic-and-environmental-structure-of-dsm-iv-criteria-for-antisocial-personality-disorder-a-twin-study
#19
Tom Rosenström, Eivind Ystrom, Fartein Ask Torvik, Nikolai Olavi Czajkowski, Nathan A Gillespie, Steven H Aggen, Robert F Krueger, Kenneth S Kendler, Ted Reichborn-Kjennerud
Results from previous studies on DSM-IV and DSM-5 Antisocial Personality Disorder (ASPD) have suggested that the construct is etiologically multidimensional. To our knowledge, however, the structure of genetic and environmental influences in ASPD has not been examined using an appropriate range of biometric models and diagnostic interviews. The 7 ASPD criteria (section A) were assessed in a population-based sample of 2794 Norwegian twins by a structured interview for DSM-IV personality disorders. Exploratory analyses were conducted at the phenotypic level...
May 2017: Behavior Genetics
https://www.readbyqxmd.com/read/28092418/an-examination-of-the-etiologic-overlap-between-the-genetic-and-environmental-influences-on-insomnia-and-common-psychopathology
#20
Mackenzie J Lind, Sage E Hawn, Christina M Sheerin, Steven H Aggen, Robert M Kirkpatrick, Kenneth S Kendler, Ananda B Amstadter
BACKGROUND: Insomnia is comorbid with internalizing and externalizing psychiatric disorders. However, the extent to which the etiologic influences on insomnia and common psychopathology overlap is unclear. There are limited genetically informed studies of insomnia and internalizing disorders and few studies of overlap exist with externalizing disorders. METHODS: We utilized twin data from the Virginia Adult Twin Studies of Psychiatric and Substance Use Disorders (total n = 7,500)...
May 2017: Depression and Anxiety
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