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Nkeoma Nkasi Okoye, Daniel Lotanna Ajaghaku, Henry Nnaemeka Okeke, Emmanuel Emeka Ilodigwe, Chukwuemeka Sylvester Nworu, Festus Basden C Okoye
CONTEXT: Alstonia boonei De Wild (Apocyanaceae) is used in ethnomedicine for the management of malaria, ulcer, rhematic pain, toothache, and inflammatory disorders. OBJECTIVE: To investigate the anti-inflammatory potential of β-amyrin and α-amyrin acetate isolated from the stem bark of Alstonia boonei using animal models. MATERIALS AND METHODS: Chromatographic purification of the crude methanol extract led to the isolation and structure elucidation of β-amyrin and α-amyrin acetate...
November 2014: Pharmaceutical Biology
Athanasios Madesis, Kosmas Tsakiridis, Paul Zarogoulidis, Nikolaos Katsikogiannis, Nikolaos Machairiotis, Ioanna Kougioumtzi, George Kesisis, Theodora Tsiouda, Thomas Beleveslis, Alexander Koletas, Konstantinos Zarogoulidis
Mitral valve (MV) dysfunction is the second-most common clinically significant form of valvular defect in adults. MV regurgitation occurs with the increasing frequency of degenerative changes of the aging process. Moreover, other causes of clinically significant MV regurgitation include cardiac ischemia, infective endocarditis and rhematic disease more frequently in less developed countries. Recent evidence suggests that the best outcomes after repair of severe degenerative mitral regurgitation (MR) are achieved in asymptomatic or minimally symptomatic patients, who are selected for surgery soon after diagnosis on the basis of echocardiography...
March 2014: Journal of Thoracic Disease
No abstract text is available yet for this article.
January 7, 1961: Wiener Medizinische Wochenschrift
J C Antoine, D Michel, P Garnier, L Absi, S Boucheron, F G Barral, B Laurent
We observed a series of 9 patients (1 male, 8 females, mean age 49 years) who had experienced cerebral vascular events with livedo racemosa (Sneddon's syndrome). Vascular dementia occurred in 3 patients and in the 6 others there was a single or several acute cerebral ischaemic events. Angiography of the brain revealed multiple distal arterial occlusions in 5 cases and a moya-moya type collateral network in 2. Positivity for anticardiolipid antibodies fluctuated in 4 cases and there was a lupic syndrome in 2...
June 1994: Revue Neurologique
L V Vanina, T F Chumak, N A Guseva
No abstract text is available yet for this article.
July 1976: Voprosy Revmatizma
I Watanabe
No abstract text is available yet for this article.
March 1977: Ryūmachi. [Rheumatism]
R Virmani, W C Roberts
Among 481 patients undergoing various mitral valve operations, Aschoff bodies were found in 40 (21%) of 191 operatively excised left atrial appendages, in four (2%) of 273 operatively excised left ventricular papillary muscles (1 per patient), and in one (6%) of 17 patients with both left atrial appendage and papillary muscle operatively excised. Of the total of 45 patients with Aschoff bodies, 44 preoperatively had mitral stenosis, and only one, a 10-year-old boy, had pure mitral regurgitation. Sinus rhythm was present in 38 (84%), and atrial fibrillation in seven (16%)...
April 1977: Circulation
W C Roberts, R Virmani
Among 543 necropsy patients over age 14 years with severe chronic valvular heart disease, Aschoff bodies were found in 11 patients (2%). The ages of the 11 patients ranged from 18 to 68 years (avg. 38), and nine had had a history of acute rhematic fever earlier in life. Clinically, nine of the 11 patients had mitral stenosis with or without dysfunction of one or more other cardiac valves, one had isolated aortic regurgitation, and one had both mitral and aortic regurgitation. All 11 patients had diffuse fibrous thickening of the mitral valve leaflets, and all but one had diffuse anatomic lesions of at least one other cardiac valve...
April 1978: Circulation
N N Gritsman, M S Rusakova, M Vykidal, T Prachke, K Dushek
No abstract text is available yet for this article.
October 1977: Voprosy Revmatizma
E H Yelin, C J Henke, W V Epstein
Californian specialists in the treatment of rheumatic diseases were surveyed to determine the spatial distribution of rheumatologic services in the state, the amount of patient care time available for the rhematic diseases in each county, the physicians' capacity to treat all rhemmatic disease patients who seek their care, and their perception of the need for more specialists in their area. The data resulting from the survey are analyzed by four methods to assess the sufficiency of medical manpower resoruces...
April 1977: Arthritis and Rheumatism
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