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clonidine epidural

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https://www.readbyqxmd.com/read/28928573/a-comparative-study-for-the-analgesic-efficacy-and-safety-profile-of-fentanyl-versus-clonidine-as-an-adjuvant-to-epidural-ropivacaine-0-75-in-lower-abdominal-surgeries
#1
Shuchi Nigam, Shivani Rastogi, Amit Tyagi, Rajlakshmi Bhandari
CONTEXT: Different adjuvants are coadministered with local anesthetics to improve the speed of onset and duration of analgesia, and to reduce the dose, the selection of which is often left to the choice of an anesthesiologist. AIM: The aim of this study was to compare the analgesic efficacy and safety profile of fentanyl and clonidine as an adjuvant to epidural ropivacaine anesthesia. SETTING AND DESIGN: With institutional ethical committee clearance, a prospective, randomized, placebo-controlled double-blind clinical study was conducted at Vivekananda Polyclinic and Institute of Medical Sciences, Lucknow...
July 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28928565/clonidine-as-an-adjuvant-to-lignocaine-infiltration-for-prolongation-of-analgesia-after-episiotomy
#2
Upasna Bhatia, Premal Soni, Udit Khilji, Yamini N Trivedi
BACKGROUND: Epidural labor analgesia has not been fully accepted despite many advantages. Many times, the pregnant females reach hospital without antenatal checkup, and at that time, "episiotomy infiltration" becomes an ideal method for vaginal delivery. One of the most important problems after episiotomy is the severe perineal pain on the 1(st) day of postpartum period. OBJECTIVES: We compared the efficacy of clonidine 1 μg/kg as an adjuvant to 20 mg/ml lignocaine infiltration along the line of episiotomy incision for prolonging the duration and quality of analgesia with respect to various activities by single injection...
July 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28707454/interventions-for-postoperative-pain-in-children-an-overview-of-systematic-reviews
#3
REVIEW
Krste Boric, Svjetlana Dosenovic, Antonia Jelicic Kadic, Marijan Batinic, Marija Cavar, Marjan Urlic, Nikolina Markovina, Livia Puljak
The aim of this study was to conduct an overview of systematic reviews that summarizes the results about efficacy and safety from randomized controlled trials involving the various strategies used for postoperative pain management in children. We searched the Cochrane Database of Systematic Reviews, CINAHL, Database of Reviews of Effect, Embase, MEDLINE, and PsycINFO from the earliest date to January 24, 2016. This overview included 45 systematic reviews that evaluated interventions for postoperative pain in children...
September 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28663652/clonidine-as-an-adjuvant-in-fluoroscopic-guided-transforaminal-epidural-steroid-injection-in-a-patient-of-chronic-lumbosacral-radiculopathy
#4
Nandita Mehta, Misbah Salaria, A Q Salaria
Transforaminal epidural steroid injection (TFESI) is a minimally invasive modality used to treat patients with lumbosacral radiculopathy secondary to prolapsed intervertebral disc or spinal canal stenosis. In this case report, we describe the management of a patient with chronic lumbosacral radiculopathy secondary to intervertebral disc herniation which was seen as a right paracentral disc protrusion at levels L4-L5, L5-S1 causing thecal sac indentation, effacement of the right lateral recess and right exiting nerve root impingement as was seen on the magnetic resonance image...
April 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28663650/comparison-of-epidural-clonidine-and-dexmedetomidine-for-perioperative-analgesia-in-combined-spinal-epidural-anesthesia-with-intrathecal-levobupivacaine-a-randomized-controlled-double-blind-study
#5
Safiya I Shaikh, Laksmi R Revur, Marutheesh Mallappa
BACKGROUND: Epidural administrations of α2 agonists are being used as adjuvants as they lead to anxiolysis, sedation, analgesia, and hypnosis. AIM: This study aims to evaluate the analgesic effects of epidural α2 agonists-dexmedetomidine and clonidine in conjunction with intrathecal levobupivacaine in combined spinal epidural anesthesia (CSEA). METHODS: A prospective, randomized controlled study was done to assess and compare the efficacy and clinical profile of two α2 adrenergic agonists, clonidine, and dexmedetomidine administered epidurally in combination with intrathecal levobupivacaine in CSEA...
April 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28663617/comparison-between-epidural-ropivacaine-versus-ropivacaine-with-clonidine-in-patients-undergoing-abdominal-hysterectomy-a-randomized-study
#6
Keshav Govind Rao, Shilpi Misra, Aparna Shukla
CONTEXT: Regional anesthesia has emerged as one of the preferred and convenient modes for intra- and post-operative management owing to its advantage of not interfering with the metabolic functions, better tolerability, and decrease in reflex activity. In recent years, ropivacaine has increasingly replaced bupivacaine as a preferred local anesthetic because of its similar analgesic properties, lesser motor blockade, and decreased propensity of cardiotoxicity. Neuraxial adjuvant such as clonidine used in epidural anesthesia offers advantage by augmenting the local anesthetic effect and reducing the anesthetic and analgesic requirement...
April 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28620569/the-optimal-pain-management-approach-for-a-laboring-patient-a-review-of-current-literature
#7
REVIEW
Albert Kelly, Quang Tran
There is a general agreement that a patient in labor should be given the option to have an epidural block for pain management. Despite this consensus, there are differences in practice patterns as to when to initiate an epidural and how to minimize its impact on the duration and outcome of a patient's labor. A review of the literature suggests epidural analgesia does prolong stages one and two of labor, but not significantly. Cesarean delivery rates are not affected by the early initiation of epidural analgesia...
May 10, 2017: Curēus
https://www.readbyqxmd.com/read/28532200/spinal-analgesia-improves-surgical-outcome-after-open-nephrectomy-for-renal-cell-carcinoma-a-randomized-controlled-study
#8
Mascha Thurm, Britt-Inger Kröger Dahlin, Ola Winsö, Börje Ljungberg
OBJECTIVE: This study evaluated whether more effective perioperative analgesia can be part of a multimodal approach to minimizing morbidity and improving postoperative management after the open surgical approaches frequently used in the treatment of renal cell carcinoma (RCC). The aim of the study was to determine whether spinal anesthesia with clonidine can enhance postoperative analgesia, speed up mobilization and reduce the length of hospital stay (LOS). MATERIALS AND METHODS: Between 2012 and 2015, 135 patients with RCC were randomized, in addition to general anesthesia, to receive either spinal analgesia with clonidine or epidural analgesia, stratified to surgical technique...
May 22, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/27795779/postoperative-analgesia-in-children-when-using-clonidine-in-addition-to-fentanyl-with-bupivacaine-given-caudally
#9
RANDOMIZED CONTROLLED TRIAL
Anouar Jarraya, Sahar Elleuch, Jawhar Zouari, Mohamed Smaoui, Sofiene Laabidi, Kamel Kolsi
The aim of the study was to evaluate the efficacy of clonidine in association with fentanyl as an additive to bupivacaine 0.25% given via single shot caudal epidural in pediatric patients for postoperative pain relief. In the present prospective randomized double blind study, 40 children of ASA-I-II aged 1-5 years scheduled for infraumblical surgical procedures were randomly allocated to two groups to receive either bupivacaine 0.25% (1 ml/kg) with fentanyl 1 μg/kg and clonidine 1μg/kg (group I) or bupivacaine 0...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27550555/caudal-analgesia-and-cardiothoracic-surgery-a-look-at-postoperative-pain-scores-in-a-pediatric-population
#10
Khoa N Nguyen, Heather S Byrd, Jonathan M Tan
AIM: Caudal epidural anesthesia has been shown to reduce stress response and shorten the time to extubation in children after cardiac surgery. Combined with general anesthesia, regional anesthesia has been proven to be safe and efficacious in the pediatric population. It is not known, however, whether the use of caudal anesthesia actually reduces postoperative pain scores and decreases postoperative opioid use. METHODS: We retrospectively analyzed the charts of 199 children who underwent repair for atrial septal defect (ASD), ventricular septal defect (VSD), and Tetralogy of Fallot (TOF) at a major academic children's hospital between 2010 and 2013...
November 2016: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/27330201/effect-of-epidural-clonidine-on-characteristics-of-spinal-anaesthesia-in-patients-undergoing-gynaecological-surgeries-a-clinical-study
#11
Rachna Prasad, Rs Raghavendra Rao, Ashwini Turai, P Prabha, R Shreyavathi, Karuna Harsoor
BACKGROUND AND AIMS: Combined spinal-epidural (CSE) anaesthesia is being increasingly used for effective post-operative analgesia. This study was designed to evaluate the effect of epidural clonidine on characteristics of spinal anaesthesia for gynaecological surgeries. METHODS: This was a prospective randomised, double-blind, controlled study involving sixty patients belonging to American Society of Anesthesiologists Physical Status I and II who underwent gynaecological surgeries were randomly divided into clonidine (C) group and saline (S) group of thirty each...
June 2016: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/27275050/the-efficacy-and-safety-of-epidural-dexmedetomidine-and-clonidine-with-bupivacaine-in-patients-undergoing-lower-limb-orthopedic-surgeries
#12
Safiya I Shaikh, Sarala B Mahesh
BACKGROUND AND AIMS: Alpha (α-2) adrenergic agonists have both analgesic and sedative properties when used as an adjuvant in regional anesthesia. A prospective randomized double-blind study was carried out to evaluate the efficacy of epidural route and to compare the efficacy and clinical profile of dexmedetomidine and clonidine as an adjuvant to bupivacaine with special emphasis on their quality of analgesia, sedation and the ability to provide the smooth intra-operative and postoperative course...
April 2016: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/27212752/dexmedetomidine-as-an-adjuvant-to-bupivacaine-in-caudal-analgesia-in-children
#13
Vigya Goyal, Jyotsna Kubre, Krishnaprabha Radhakrishnan
CONTEXT: Postoperative pain management is becoming an integral part of anesthesia care. Various techniques of pediatric pain relief have been designed among which the most commonly practiced is caudal epidural block. Several adjuvants have been used to prolong the duration of caudal analgesia such as clonidine, neostigmine, ketamine, opioids, and ephedrine. We have designed the study using dexmedetomidine as an adjuvant to assess analgesic efficacy, duration of postoperative analgesia, hemodynamic stability, postoperative sedation, and any adverse effects in children...
May 2016: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/27212750/comparative-study-for-better-adjuvant-with-ropivacaine-in-epidural-anesthesia
#14
Pramila Soni
BACKGROUND: Better adjuvants for epidural analgesia are still evolving. Dexmedetomidine that is alpha-2 agonist can be used as an adjuvant in epidural analgesia and anesthesia. AIMS: The aim of this study was to compare the effect of dexmedetomidine versus clonidine in combination with ropivacaine in epidural anesthesia on intraoperative and postoperative analgesia, to find out the better adjuvant for regional anesthesia. SETTINGS AND DESIGN: Randomized control trial...
May 2016: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/27061848/continuous-chest-wall-ropivacaine-infusion-for-analgesia-in-children-undergoing-nuss-procedure-a-comparison-with-thoracic-epidural
#15
COMPARATIVE STUDY
Dinesh K Choudhry, B Randall Brenn, Karen Sacks, Kirk Reichard
BACKGROUND: Pain following Nuss procedure is severe and its management is challenging. Many different pain treatment modalities are currently being used, but none of them have been found to be ideal. AIM: In this retrospective review, we compare our current multimodal approach, which involves continuous ropivacaine infusion through chest wall catheters (CWC), intravenous patient-controlled analgesia (IV-PCA), and adjunctive medications (gabapentin and clonidine), with the technique that we used in the past, the thoracic epidural catheter (TEC)...
June 2016: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/27053792/epidural-clonidine-for-the-anaesthetic-management-for-diagnostic-procedure
#16
Sangeeta Agarwal Bansal, Yogesh Tilkar, Sanjeevani Karmalkar
No abstract text is available yet for this article.
March 2016: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/26957695/comparative-evaluation-of-dexmedetomidine-and-clonidine-with-low-dose-ropivacaine-in-cervical-epidural-anesthesia-for-modified-radical-mastectomy-a-prospective-randomized-double-blind-study
#17
Shivakumar M Channabasappa, Gopinath H Venkatarao, Shobha Girish, Nandakishore K Lahoti
CONTEXT: Alpha-2 adrenergic agonists clonidine and dexmedetomidine, are well known to produce analgesia through an opioid independent mechanism. Alpha-2 agonists are used as an adjuvant to local anesthetic agents to extend the duration of spinal, epidural and brachial plexus blocks. AIMS: We compared clonidine and dexmedetomidine as an adjuvant to Ropivacaine in cervical epidural anesthesia (CEA) with respect to onset and duration of sensory block, duration of analgesia and adverse effects...
January 2016: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/26543457/comparison-of-dexmedetomidine-and-clonidine-as-an-adjuvant-to-ropivacaine-for-epidural-anesthesia-in-lower-abdominal-and-lower-limb-surgeries
#18
Sruthi Arunkumar, V R Hemanth Kumar, N Krishnaveni, M Ravishankar, Velraj Jaya, M Aruloli
BACKGROUND: The quality and duration of analgesia is improved when a local anesthetic is combined with alpha 2 adrenergic agonist. Though, the effects of clonidine on local anesthetics have been extensively studied, there are limited studies demonstrating the effects of epidural dexmedetomidine on local anesthetics. The aim of our study is to compare the effect of clonidine and dexmedetomidine when used as an adjuvant to epidural ropivacaine in lower abdominal and lower limb surgeries...
October 2015: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/26500983/evaluation-of-efficacy-of-epidural-clonidine-with-0-5-bupivacaine-for-postoperative-analgesia-for-orthopaedic-lower-limb-surgeries
#19
Karthik Krishnamoorthy, Saravanan Ravi, Ilango Ganesan
OBJECTIVE: The objective of this study is to evaluate the efficacy of epidural clonidine in intra and postoperative analgesia, the level of sedation caused by clonidine and monitor its side effects. MATERIALS AND METHODS: Forty patients of ASA1 & ASA2 scheduled for lower limb orthopaediac surgeries were chosen for the study. Study group received 50μg of clonidine diluted to 1ml along with first dose of epidural injection and Control group received 1ml of normal saline along with first dose of epidural...
September 2015: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26495267/paravertebral-analgesia-in-transapical-transcatheter-aortic-valve-replacement
#20
Justin M Poltak, Frederick C Cobey, John G Augoustides, Christopher W Connors
INTRODUCTION: Transapical transcatheter aortic valve replacement is an option for patients who are not candidates for traditional aortic valve surgery but have severe aortic stenosis and unfavorable ileo-femoral anatomy. Epidural analgesia in these cases has been associated with improved morbidity and mortality. The following manuscript presents the findings of an initial clinical experience employing paravertebral analgesia for patients undergoing transapical transcatheter aortic valve replacement...
2015: Heart, Lung and Vessels
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