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https://www.readbyqxmd.com/read/27911382/a-simple-mechanical-procedure-to-create-limbal-stem-cell-deficiency-in-mouse
#1
Neda Afsharkhamseh, Elham Ghahari, Medi Eslani, Ali R Djalilian
Limbal stem cell deficiency (LSCD) is a state of malfunction or loss of limbal epithelial stem cells, after which the corneal epithelium is replaced with conjunctiva. Patients suffer from recurrent corneal defects, pain, inflammation, and loss of vision. Previously, a murine model of LSCD was described and compared to two other models. The goal was to produce a consistent mouse model of LSCD that both mimics the phenotype in humans and lasts long enough to make it possible to study the disease pathophysiology and to evaluate new treatments...
November 17, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27900778/predicting-post-traumatic-stress-disorder-treatment-response-in-refugees-multilevel-analysis
#2
Joris F G Haagen, F Jackie June Ter Heide, Trudy M Mooren, Jeroen W Knipscheer, Rolf J Kleber
OBJECTIVES: Given the recent peak in refugee numbers and refugees' high odds of developing post-traumatic stress disorder (PTSD), finding ways to alleviate PTSD in refugees is of vital importance. However, there are major differences in PTSD treatment response between refugees, the determinants of which are largely unknown. This study aimed at improving PTSD treatment for adult refugees by identifying PTSD treatment response predictors. DESIGN: A prospective longitudinal multilevel modelling design was used to predict PTSD severity scores over time...
November 30, 2016: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/27900183/severity-and-pattern-of-injuries-caused-by-the-traditional-swiss-team-sport-hornussen-first-retrospective-study-at-a-level-i-trauma-centre-in-switzerland
#3
Volkmar Waterkamp, Meret Ricklin, Benoît Schaller, Konstantinos Katsoulis, Aristomenis Exadaktylos
BACKGROUND: This article addresses typical injury patterns related to the traditional Swiss team sport of Hornussen. A small plastic disk is struck with a special elastic racket and then intercepted in the field. Severe injuries have occasionally been reported. We present a systematic review of all cases of Hornussen injuries treated in the University Hospital of Bern from 2000 to 2014. METHODS: To assess the frequency, type and outcome of Hornussen injuries, we performed a database search of all inpatient and outpatient cases related to Hornussen and that were admitted to and/or treated in Bern University Hospital from 2000 to 2014...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27895365/indications-of-enucleations-and-eviscerations-performed-at-a-tertiary-eye-care-unit-a-case-series
#4
Rashid Baig, Maheen Akhtar Syed, Khabir Ahmad, Tanveer Anjum Chaudhry
The retrospective study was planned to look at the indications of eye enucleations and eviscerations, and comprised all such procedures done at the Aga Khan University Hospital, Karachi, from January 2006 to December 2015. Data was collected regarding age at the time of procedure, gender, procedure type, indication for enucleation or evisceration, type of implant if used and complications. Of the 66 eyes of 65 individuals, 47 (71.2%) underwent evisceration and 19 (28.8%) enucleation. The mean age at the time of the procedures was 37...
October 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27895364/a-10-year-review-of-indications-for-penetrating-keratoplasty-in-a-tertiary-care-setting-in-karachi-pakistan
#5
Tanveer Ajum Chaudhry, Salman Naveed Sadiq, Zubaida Sirang, Maheen Akhtar Syed, Mustafa Kamal, Khabir Ahmad
The retrospective study was conducted to determine the indications and outomes of penetrating keratoplasty(PKP) in a tertiary care setting in Pakistan. All eyes that had undergone PKP between January 2005 and December 2014 at the Aga Khan University Hospital, Karachi, were included.Data were collected on the indications of PKP, graft survival (graft clarity at final follow-up), andbest corrected visual acuity (BCVA).Kaplan-Meier\'s method was usedto analyse graft survival.Out of 437 eyes, 383(87%) were for visual purpose...
October 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27890246/treatment-of-dynamic-scapholunate-instability-dissociation-contribution-of-arthroscopy
#6
C Mathoulin
Scapholunate (SL) ligament injuries generally result from trauma to an extended, supinated wrist, leading to chronic instability that progresses toward osteoarthritis. They can occur together with distal radius fracture. These injuries can be difficult to diagnose, especially early on. Treating chronic SL ligament injuries before the onset of osteoarthritis is still a challenge for surgeons. Until recently, the recommended treatments consisted of open SL ligament reconstruction or repair procedures that reduce pain and improve pinch strength but also lead to wrist stiffness...
December 2016: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/27890189/diplopia-what-to-double-check-in-radiographic-imaging-of-double-vision
#7
REVIEW
Claudia F E Kirsch, Karen Black
When patients see double with both eyes open, known as "binocular diplopia," this may be a harbinger of underlying life-threatening causes. This article presents pertinent anatomy, critical abnormality, and radiographic features that should be double checked for in diplopia. Key areas requiring a double check using the acronym VISION include Vascular, Infectious and Inflammatory, the Scalp for giant cell arteritis, Sphenoid and Skull base in trauma, Increased intracranial pressure (pseudotumor cerebri), Onset of new headaches or psychosis, and Neoplasm...
January 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/27885526/twelve-year-follow-up-of-penetrating-keratoplasty
#8
Takashi Ono, Sosuke Ishiyama, Takeshi Hayashidera, Yosai Mori, Ryohei Nejima, Kazunori Miyata, Shiro Amano
PURPOSE: To evaluate the long-term outcomes of penetrating keratoplasty (PKP) according to the corneal disease diagnosis and the number of PKP procedures performed. METHODS: Five-hundred-and-nine eyes from 403 patients who underwent PKP at Miyata Eye Hospital in Japan from 1998 through 2014, were included in this study. Medical charts were retrospectively examined to ascertain the corneal disease diagnosis and the period of graft survival. Graft survival rates were compared among various corneal disease diagnoses and among the number of PKP procedures performed...
November 24, 2016: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27881180/polypharmacy-and-adverse-outcomes-after-hip-fracture-surgery
#9
Maria Härstedt, Cecilia Rogmark, Richard Sutton, Olle Melander, Artur Fedorowski
BACKGROUND: We aimed to explore the effects of polypharmacy and specific drug classes on readmissions and mortality after hip surgery. METHODS: We analyzed data on 272 consecutive hip fracture patients (72.1% females; age 82 ± 9 years) who underwent acute hip replacement. We collected detailed data on the pharmacological treatment upon admission and discharge. Patients were followed up over a period of 6 months after discharge using the Swedish National Hospital Discharge Register and the Swedish National Cause of Death Register...
November 24, 2016: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/27874147/open-globe-eye-injury-characteristics-and-prognostic-factors-in-jazan-saudi-arabia
#10
Mashaal A Makhrash, Ibrahim M Gosadi
To evaluate characteristics and prognostic factors of open globe injuries (OGI) presented to King Fahad Specialist Hospital in the Jazan region, Saudi Arabia.  Methods: This study is a retrospective review of medical records of OGI patients who underwent operative repair of their injuries in King Fahad Central Hospital, Jazan, Saudi Arabia between January 2011 and December 2013. Demographic information, eye injury, preoperative, and postoperative visual acuity were collected. The initial and final visual acuity outcomes were compared to identify subjects who witnessed any improvement in their visual acuity...
December 2016: Saudi Medical Journal
https://www.readbyqxmd.com/read/27863285/finite-element-analysis-and-experimental-evaluation-of-penetrating-injury-through-the-cornea
#11
Scott T Lovald, Andrew Rau, Steven Nissman, Nicoli Ames, John McNulty, Jorge A Ochoa, Michael Baldwinson
Penetration injuries of the eye are among the most frequent causes of permanent visual impairment resulting from trauma. The purpose of this study was to determine the peak strain at which rupture occurs in the cornea due to a penetrating object. Probes of varying diameters (1.0, 1.5, and 2.0mm) were pressed into the apex of the cornea of 36 human cadaveric eye specimens until perforation or rupture of the specimen at the cornea, limbus, or sclera occurred. An axisymmetric finite element model of the human globe was created to replicate the experimental set-up...
November 3, 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/27856946/eye-trauma-in-laurel-and-hardy-movies-another-nice-mess
#12
Lara DA Zegers, Richard Hc Zegers
BACKGROUND AND AIMS: One of the characteristics in Laurel and Hardy films is a lot of physical violence. The present study examines the occurrence of eye trauma in Laurel and Hardy movies and discusses the impact they could have been had if the films were set in reality. METHODS AND RESULTS: All 92 movies starring Laurel and Hardy as a pair in leading roles were watched together by the authors and were scored for any eye trauma. Eighty-eight eye traumas happened, of which 48% were directed at Hardy...
November 2016: Scottish Medical Journal
https://www.readbyqxmd.com/read/27849319/traumatic-wound-dehiscence-after-penetrating-keratoplasty
#13
Özlem Barut Selver, Melis Palamar, Sait Eğrilmez, Ayşe Yağcı
BACKGROUND: The aim of this study was to evaluate risks and consequences of traumatic wound dehiscence after penetrating keratoplasty (PK). METHODS: Data regarding 34 eyes of 34 patients who were treated for traumatic wound dehiscence after PK between 1995 and 2014 were studied. Patient records were reviewed for type and time of insult, corrected distance visual acuity (CDVA), clinical presentation signs, operative method, and outcome. RESULTS: The interval between PK and trauma ranged from 1 month to 100 months, with median of 14 months...
September 2016: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/27843433/successful-treatment-of-lasiodiplodia-theobromae-keratitis-assessing-the-role-of-voriconazole
#14
Stephen Tak-Lun Li, Evan Po-Fat Yiu, Angela Hiu-Yan Wong, John Chun-Ting Yeung, Lester Wang-Hon Yu
PURPOSE: The aim of this paper is to report the successful management of the first case of Lasiodiplodia theobromae keratitis in Hong Kong. METHODS: We conducted a case report. RESULTS: A 43-year-old Chinese male with a history of diabetes developed left eye keratitis after a trauma during tree felling. Fungal keratitis was diagnosed using a confocal microscope on day 1, and L. theobromae was confirmed from the culture. He was given oral voriconazole, topical natamycin, and topical and intracameral amphotericin B...
September 2016: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/27843275/current-trends-in-treatment-outcomes-of-orbital-cellulitis-in-a-tertiary-hospital-in-southern-nigeria
#15
Odarosa M Uhumwangho, Dumebi H Kayoma
BACKGROUND: Orbital cellulitis refers to the inflammation or infection of the soft tissues of the orbit located behind the orbital septum. AIM: To determine the current trends in the outcomes following the management of orbital cellulitis in a tertiary hospital in Southern Nigeria. PATIENTS AND METHODS: A retrospective review of medical records of patients with orbital cellulitis from January 2008 to December 2014 was conducted. The age, sex, duration of symptoms, predisposing factors, clinical findings, laboratory/radiological investigations, treatment provided, complications, and follow-up were recorded...
July 2016: Nigerian Journal of Surgery: Official Publication of the Nigerian Surgical Research Society
https://www.readbyqxmd.com/read/27833677/somnambulism-emergency-department-admissions-due-to-sleepwalking-related-trauma
#16
Thomas C Sauter, Sajitha Veerakatty, Dominik G Haider, Thomas Geiser, Meret E Ricklin, Aristomenis K Exadaktylos
INTRODUCTION: Somnambulism is a state of dissociated consciousness, in which the affected person is partially asleep and partially awake. There is pervasive public opinion that sleepwalkers are protected from hurting themselves. There have been few scientific reports of trauma associated with somnambulism and no published investigations on the epidemiology or trauma patterns associated with somnambulism. METHODS: We included all emergency department (ED) admissions to University Hospital Inselspital, Berne, Switzerland, from January 1, 2000, until August 11, 2015, when the patient had suffered a trauma associated with somnambulism...
November 2016: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27828913/long-term-results-of-total-retinectomy-in-cases-with-advanced-proliferative-vitreoretinopathy
#17
Murat Karacorlu, Isil Sayman Muslubas, Mumin Hocaoglu, Serra Arf, Mehmet Giray Ersoz
PURPOSE: To evaluate the long-term results of total retinectomy in patients with rhegmatogenous retinal detachment and severe proliferative vitreoretinopathy. METHODS: Seven eyes of 7 patients had pars plana vitrectomy, with or without pars plana lensectomy, and total retinectomy, with or without silicone oil tamponade, for the management of rhegmatogenous retinal detachment and proliferative vitreoretinopathy (Grade D1-3) after previous complex vitreoretinal surgery procedures...
November 8, 2016: Retina
https://www.readbyqxmd.com/read/27826683/aspergillus-flavus-keratitis-experience-of-a-tertiary-eye-clinic-in-turkey
#18
Elif Erdem, Meltem Yagmur, Hazal Boral, Macit Ilkit, Reha Ersoz, Seyedmojtaba Seyedmousavi
We investigated the clinical and mycological characteristics of four cases of mycotic keratitis caused by Aspergillus flavus that occurred from July 2014 to May 2015 at Çukurova University Hospital, Adana, Turkey. In a 10-month period, a total of 64 corneal smear/scrapings were examined from patients with suspected mycotic keratitis. Fungal cultures were positive in six of these patients, indicating a 9.4% incidence of mycotic keratitis in this region, including four cases of A. flavus and two cases of Fusarium spp...
November 8, 2016: Mycopathologia
https://www.readbyqxmd.com/read/27824317/concomitant-macular-hole-and-central-serous-chorioretinopathy-after-blunt-eye-trauma
#19
Kemal Tekin, Mehmet Citirik, Muhammed Atalay, Mehmet Yasin Teke
PURPOSE: To report concomitant macular hole and central serous chorioretinopathy after blunt trauma. METHODS: Case presentation. A 31-year-old man presented with a complaint of a reduction in visual acuity and blurred vision in the right eye after blunt eye trauma. The patient did not have a history of any systemic disorders and drug administration. RESULTS: On ocular examination, best corrected visual acuity was 2/20 in the right eye and 20/20 in the left eye...
October 11, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27813034/-horner-syndrome-following-combined-spinal-epidural-anesthesia
#20
Ömer Karaca, Sezen Kumaş Solak, Serdar Demirgan, Mehmet Bademci
Horner syndrome is rarely observed in connection with epidural anesthesia. It is characterized by ptosis, enophthalmos, miosis, anisocoria, and conjunctival hyperemia in the affected eye, as well as anhydrosis and flushing on the affected side of the face. It is usually a complication spontaneously resolved without permanent neurological deficits. Intraoral anesthesia; stellate ganglion, cervical or brachial plexus blocks; thoracic, lumbar or caudal epidural anesthesia, and intrapleural analgesia are the main causes for Horner syndrome related to anesthesia...
July 2016: Aǧrı: Ağrı (Algoloji) Derneği'nin Yayın Organıdır, the Journal of the Turkish Society of Algology
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