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https://www.readbyqxmd.com/read/29140137/v%C3%AC-o2-and-muscle-deoxygenation-kinetics-during-skating-comparison-between-slide-board-and-treadmill-skating
#1
Tatiane Piucco, Rogério Soares, Fernando Diefenthaeler, Guillaume Millet, Juan Murias
PURPOSE: this study aimed to compare the oxygen uptake (V̇O2) kinetics during skating on a treadmill and skating on a slide board and discuss potential mechanisms that might control the V̇O2 kinetics responses during skating. METHODS: breath-by-breath pulmonary V̇O2 and near-infrared spectroscopy-derived muscle deoxygenation ([HHbMb]) were monitored continuously in 12 well-trained young long track speed skaters. On-transient V̇O2 and [HHbMb] responses to skating on a treadmill and skating on a slide board at 80% of the estimated gas exchange threshold were fitted as mono-exponential function...
November 15, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29138489/a-dual-channel-endoscope-for-quantitative-imaging-monitoring-and-triggering-of-doxorubicin-release-from-liposomes-in-living-mice
#2
Jeremy Kress, Daniel J Rohrbach, Kevin A Carter, Dandan Luo, Chien Poon, Semra Aygun-Sunar, Shuai Shao, Shashikant Lele, Jonathan F Lovell, Ulas Sunar
Doxorubicin (Dox) is approved for use in liposomal form for the treatment of ovarian cancer. We previously developed a long-circulating Dox formulation in liposomes containing small amounts of porphyrin-phospholipid, which enables on-demand drug release with near-infrared irradiation. In this study, we present and evaluate a dual-modal, dual-channel light endoscope that allows quantitative reflectance and fluorescence imaging for monitoring of local Dox concentrations in target areas. The endoscope consists of two flexible imaging fibers; one to transmit diagnostic and therapeutic light to the target, and the other to detect fluorescent and reflected light...
November 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29137772/sonochemical-synthesis-of-co2sno4-nanocubes-for-supercapacitor-applications
#3
Balasubramaniam Gnana Sundara Raj, Senniyappan Bhuvaneshwari, Jerry J Wu, Abdullah M Asiri, Sambandam Anandan
In this work, a simple sonochemical route was followed to synthesize cobalt stannate (Co2SnO4) nanocubes using stannous and cobalt chlorides as the precursors in alkaline medium at room temperature. The structure, composition and surface morphology of synthesized Co2SnO4 nanocubes have been characterized by using X-ray diffraction analysis (XRD), Fourier transform infrared spectroscopy (FT-IR), Field emission scanning electron microscopy (FE-SEM) and high-resolution transmission electron microscopy (HR-TEM) indicates that the Co2SnO4 nanocubes are crystalline, single-phase without any impurity phase; the sizes of nanocubes are ∼100 nm...
March 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/29135482/long-term-darapladib-use-does-not-affect-coronary-plaque-composition-assessed-using-multimodality-intravascular-imaging-modalities-a-randomized-controlled-study
#4
Woong Gil Choi, Megha Prasad, Ryan Lennon, Rajiv Gulati, Abhiram Prasad, Lilach O Lerman, Amir Lerman
BACKGROUND: Lipoprotein-associated phospholipase A2 (Lp-PLA2) may play a role in plaque progression and vulnerability. We aimed to define plaque characteristics on multimodality intravascular imaging in patients with coronary endothelial dysfunction in response to long-term inhibition of Lp-PLA2 by darapladib. PATIENTS AND METHODS: This is a double-blinded, randomized study screening 70 patients, and enrolling 54 patients with suspected ischemia, without obstructive disease on angiography and with coronary endothelial dysfunction by invasive assessment...
November 10, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29130676/-the-feasibility-of-ct-attenuation-value-to-predict-the-composition-of-upper-urinary-calculi-and-success-rate-of-extracorporeal-shock-wave-lithotripsy
#5
Yu Fan, Zhen-Hua Liu, Qiang Wei, Zhuang Tang, Liang-Ren Liu, Bi-Hua Ren, Xiang Li, Yi-Ge Bao, Lu Yang
OBJECTIVE: To explore the feasibility of CT attenuation value (CTvalue) to predict the composition of upper urinary calculi and the number of shock waves (NSW) and success rate (SR) of extracorporeal shock wave lithotripsy (ESWL). METHODS: A total of 146 patients with upper urinary calculi treated by ESWL were included. CT scan was performed before ESWL. Upper urinary calculi with the maximum diameters of less than or equal to 2 cm were included. Infrared spectroscopy was used to analyze the composition of calculi...
September 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/29125675/simultaneous-application-of-photothermal-therapy-and-anti-inflammatory-prodrug-using-pyrene-aspirin-loaded-gold-nanorod-graphitic-nanocapsules
#6
Qian Dong, Xuewei Wang, Xiaoxiao Hu, Langqiu Xiao, Liang Zhang, Lijuan Song, Minglu Xu, Yuxiu Zou, Long Chen, Zhuo Chen, Weihong Tan
Photothermal therapy (PTT) has been extensively developed as an effective approach against cancer. In some cases, however, PTT can trigger inflammatory responses, in turn simulating tumor regeneration and hindering subsequent therapy. We herein developed a therapeutic strategy able to deliver enhanced PTT and simultaneously inhibite PTT-induced inflammatory response. 1-Pyrene methanol was utilize to synthesize anti-inflammatory prodrug pyrene-aspirin (P-aspirin) with cleavable ester bond, and also facilitate loading the prodrug on gold nanorod (AuNR)-encapsulated graphitic nanocapsule (AuNR@G), a photothermal agent, through π-π interaction...
November 10, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/29125162/controlled-optical-characteristics-of-lanthanide-doped-upconversion-nanoparticles-for-emerging-applications
#7
Xiaoqian Ge, Jinliang Liu, Lining Sun
Lanthanide-doped upconversion nanoparticles (UCNPs) can convert long wavelength excitation radiation in the near-infrared region to higher energy emission radiation from ultraviolet to near-infrared. The anti-Stokes luminescence process will result in high tissue penetration depth, low background noise and low photo-damage in bioimaging applications. Considering these excellent optical performances, UCNPs have been considered as the next generation of fluorescent probes for sensing and bioimaging based on near-infrared light stimulation...
November 10, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29124878/preparation-and-characterization-of-a-novel-molecularly-imprinted-polymer-for-the-separation-of-glycyrrhizic-acid
#8
Jiapeng Long, Bing Liang, Sanxi Li, Zhenbin Chen
Molecularly imprinted polymers of glycyrrhizic acid were prepared by solution polymerization using glycyrrhizic acid as the template molecule, N-vinypyrrolidone as functional monomer, N,N-methylene bisacrylamide as cross-linker and ascorbic acid and hydrogen peroxide as initiators. Focused on the adsorption capacity and separation degree of the polymer to glycyrrhizic acid, the effects of the monomers, crosslinker and initiators were investigated and optimized. Finally, the structure of the polymer was characterized by using Fourier transform infrared spectroscopy and scanning electron microscopy...
November 10, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/29121667/quantifying-unpredictability-a-multiple-model-approach-based-on-satellite-imagery-data-from-mediterranean-ponds
#9
Lluis Franch-Gras, Eduardo Moisés García-Roger, Belen Franch, María José Carmona, Manuel Serra
Fluctuations in environmental parameters are increasingly being recognized as essential features of any habitat. The quantification of whether environmental fluctuations are prevalently predictable or unpredictable is remarkably relevant to understanding the evolutionary responses of organisms. However, when characterizing the relevant features of natural habitats, ecologists typically face two problems: (1) gathering long-term data and (2) handling the hard-won data. This paper takes advantage of the free access to long-term recordings of remote sensing data (27 years, Landsat TM/ETM+) to assess a set of environmental models for estimating environmental predictability...
2017: PloS One
https://www.readbyqxmd.com/read/29121605/nano-rod-ca-decorated-sludge-derived-carbon-for-removal-of-phosphorus
#10
Lingjun Kong, Meina Han, Kaimin Shih, Minhua Su, Zenghui Diao, Jianyou Long, Diyun Chen, Li'an Hou, Yan Peng
Recovering phosphorus (P) from waste streams takes the unique advantage in simultaneously addressing the crisis of eutrophication and the shortage of P resource. A novel calcium decorated sludge carbon (Ca-SC) was developed from dyeing industry wastewater treatment sludge by decorating calcium (Ca) to effectively adsorb phosphorus from solution. The X-ray diffraction (XRD) and Fourier transform infrared (FTIR) techniques were used to characterize the Ca-SCs, followed by isotherm and kinetic sorption experiments...
November 6, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29119947/visible-to-near-infrared-photodetectors-based-on-mos2-vertical-schottky-junctions
#11
Fan Gong, Hehai Fang, Peng Wang, Meng Su, Qing Li, Johnny C Ho, Xiaoshuang Chen, Wei Lu, Lei Liao, Jun Wang, Weida Hu
Over the past few years, two-dimensional (2D) nanomaterials, such as MoS2, have been widely considered as the promising channel materials for next-generation high-performance phototransistors. However, their device performances still mostly suffer from slow photoresponse (e.g. with the time constant in the order of milliseconds) due to the relatively long channel length and the substantial surface defect induced carrier trapping, as well as the insufficient detectivity owing to the relatively large dark current...
November 9, 2017: Nanotechnology
https://www.readbyqxmd.com/read/29118388/near-infrared-light-decreases-synaptic-vulnerability-to-amyloid-beta-oligomers
#12
Michele M Comerota, Balaji Krishnan, Giulio Taglialatela
Synaptic dysfunction due to the disrupting binding of amyloid beta (Aβ) and tau oligomers is one of the earliest impairments in Alzheimer's Disease (AD), driving initial cognitive deficits and clinical manifestation. Consequently, there is ample consensus that preventing early synaptic dysfunction would be an effective therapeutic strategy for AD. With this goal in mind, we investigated the effect of a treatment of mice with near infrared (NIR) light on synaptic vulnerability to Aβ oligomers. We found that Aβ oligomer binding to CNS synaptosomes isolated from wild type (wt) mice treated with NIR light was significantly reduced and the resulting suppression of long term potentiation (LTP) by Aβ oligomers was prevented...
November 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29116536/spatial-temporal-variations-in-surface-ozone-over-ushuaia-and-the-antarctic-region-observations-from-in-situ-measurements-satellite-data-and-global-models
#13
Mohd Shahrul Mohd Nadzir, Matthew J Ashfold, Md Firoz Khan, Andrew D Robinson, Conor Bolas, Mohd Talib Latif, Benjamin M Wallis, Mohammed Iqbal Mead, Haris Hafizal Abdul Hamid, Neil R P Harris, Zamzam Tuah Ahmad Ramly, Goh Thian Lai, Ju Neng Liew, Fatimah Ahamad, Royston Uning, Azizan Abu Samah, Khairul Nizam Maulud, Wayan Suparta, Siti Khalijah Zainudin, Muhammad Ikram Abdul Wahab, Mazrura Sahani, Moritz Müller, Foong Swee Yeok, Nasaruddin Abdul Rahman, Aazani Mujahid, Kenobi Isima Morris, Nicholas Dal Sasso
The Antarctic continent is known to be an unpopulated region due to its extreme weather and climate conditions. However, the air quality over this continent can be affected by long-lived anthropogenic pollutants from the mainland. The Argentinian region of Ushuaia is often the main source area of accumulated hazardous gases over the Antarctic Peninsula. The main objective of this study is to report the first in situ observations yet known of surface ozone (O3) over Ushuaia, the Drake Passage, and Coastal Antarctic Peninsula (CAP) on board the RV Australis during the Malaysian Antarctic Scientific Expedition Cruise 2016 (MASEC'16)...
November 8, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29116136/iodide-capped-pbs-cds-core-shell-quantum-dots-for-efficient-long-wavelength-near-infrared-light-emitting-diodes
#14
Xuyong Yang, Fuqiang Ren, Yue Wang, Tao Ding, Handong Sun, Dongling Ma, Xia Wei Sun
PbS based quantum dots (QDs) have been studied in great detail for potential applications in electroluminescent devices operating at wavelengths important for telecommunications (1.3-1.6 μm). Despite the recent advances in field of quantum dot light-emitting diode (QLED), further improvements in near-infrared (NIR) emitting device performance are still necessary for the widespread use and commercialization of NIR emitting QLED technology. Here, we report a high-performance 1.51-μm emitting QLED with inverted organic-inorganic hybrid device architecture and PbS/CdS core-shell structured quantum dots as emitter...
November 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29112374/macroscopic-alignment-and-assembly-of-%C3%AF-conjugated-oligopeptides-using-colloidal-microchannels
#15
Bo Li, Lawrence R Valverde, Fengjiao Zhang, Yuecheng Zhou, Songsong Li, Ying Diao, William L Wilson, Charles M Schroeder
One-dimensional (1-D) supramolecular self-assembly offers a powerful strategy to achieve long-range unidirectional ordering of organic semiconducting materials via noncovalent interactions. Using a hierarchical assembly, electronic and optoelectronic materials can be constructed for applications including organic conducting nanowires, organic field-effect transistors (OFETs), and organic light-emitting devices (OLEDs). Despite recent progress, it remains challenging to precisely align and assemble 1-D structures over large areas in a rapid and straightforward manner...
November 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29111675/spectrum-resolved-dual-color-electrochemiluminescence-immunoassay-for-simultaneous-detection-of-two-targets-with-nanocrystals-as-tags
#16
Guizheng Zou, Xiao Tan, Xiaoyan Long, Yupeng He, Wujian Miao
A spectrum-resolved dual-color electrochemiluminescence (ECL) immunoassay was designed and implemented to simultaneously detect carcinoembryonic antigen (CEA) and alpha fetoprotein (AFP) with CdTe (λmax = 776 nm) and CdSe (λmax = 550 nm) nanocrystals (NCs) as ECL tags. The CdTe and CdSe NCs were labeled with respective probe antibodies (Ab2) of CEA and AFP, respectively, and then immobilized onto the working electrode surface via sandwich-type immunoreactions. Both CdTe and CdSe NCs within the NCs-immunocomplexes can be electrochemically reduced and simultaneously give off monochromatic ECL emissions in near-infrared and greenish region, respectively, when (NH4)2S2O8 was used as a cathodic ECL coreactant...
November 7, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29111643/kiwifruit-like-persistent-luminescent-nanoparticles-with-high-performance-and-in-situ-activable-near-infrared-persistent-luminescence-for-long-term-in-vivo-bioimaging
#17
Xia-Hui Lin, Liang Song, Shan Chen, Xiao-Feng Chen, Jing-Jing Wei, Jingying Li, Guoming Huang, Huang-Hao Yang
Persistent luminescence nanoparticles (PLNPs) have great potential for bioimaging because they can eliminate the tissue autofluorescence and improve the signal-to-noise ratio significantly. High-temperature calcination is a necessary process for the PLNPs to achieve high luminescence intensity and long afterglow time. However, high-temperature calcination usually results in uncontrollable morphology and poor homogeneity of PLNPs, which greatly limit their applications. Therefore, there is still a high demand to find a suitable method for synthesizing PLNPs with high luminescence intensity and long afterglow time while maintaining their monodispersed morphology...
November 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29110007/recent-development-of-luminescent-rhenium-i-tricarbonyl-polypyridine-complexes-as-cellular-imaging-reagents-anticancer-drugs-and-antibacterial-agents
#18
Lawrence Cho-Cheung Lee, Kam-Keung Leung, Kenneth Kam-Wing Lo
There has been fast-growing interest in the exploitation of the photophysical and photochemical properties of luminescent transition metal complexes in biological applications, with a focus on both diagnostic and therapeutic aspects. In particular, the design of luminescent rhenium(i) tricarbonyl polypyridine complexes as cellular imaging reagents and anticancer drugs has received considerable attention for a number of reasons. First, most rhenium(i) tricarbonyl polypyridine complexes possess diverse photophysical and photochemical properties through the coordination of functionalized ligands...
November 7, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29109961/the-incorporation-of-strontium-in-a-sodium-alginate-coating-on-titanium-surfaces-for-improved-biological-properties
#19
Ning Yuan, Lili Jia, Zhen Geng, Renfeng Wang, Zhaoyang Li, Xianjin Yang, Zhenduo Cui, Shengli Zhu, Yanqin Liang, Yunde Liu
Orthopedic implant failure is mainly attributed to the poor bonding of the implant to bone tissue. An effective approach to minimize the implant failure would be modifying the surface of the implant. Strontium (Sr) can stimulate the proliferation and differentiation of osteoblasts and reduce the activity of osteoclasts. In this study, a titanium (Ti) surface was successively functionalized by covalently grafting dopamine, sodium alginate (SA), and Sr(2+) via the electrostatic immobilization method. The as-prepared coatings on the Ti surface were characterized by using scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FT-IR), and contact angle...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29109786/-one-pot-fabrication-of-highly-versatile-and-biocompatible-poly-vinyl-alcohol-porphyrin-based-nanotheranostics
#20
Yan Luo, Hao Wu, Caihong Feng, Kai Xiao, Xixiao Yang, Qiangqiang Liu, Tzu-Yin Lin, Hongyong Zhang, Jeffrey H Walton, Yousif Ajena, Yide Hu, Kit S Lam, Yuanpei Li
Nanoparticle-based theranostic agents have emerged as a new paradigm in nanomedicine field for integration of multimodal imaging and therapeutic functions within a single platform. However, the clinical translation of these agents is severely limited by the complexity of fabrication, long-term toxicity of the materials, and unfavorable biodistributions. Here we report an extremely simple and robust approach to develop highly versatile and biocompatible theranostic poly(vinyl alcohol)-porphyrin nanoparticles (PPNs)...
2017: Theranostics
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