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https://www.readbyqxmd.com/read/28812023/use-of-a-polyethylene-bag-to-reduce-perioperative-regional-and-whole-body-heat-losses-in-low-birth-weight-neonates
#1
Pierre Tourneux, Estelle Durand, Amandine Pelletier, Laurent Ghyselen, Véronique Bach, Jean-Pierre Libert
In the delivery room, wrapping a low-birth-weight neonate (defined as ≤2.499 g) in a polyethylene bag reduces the risk of hypothermia. However, extended use of the bag (e.g., during neonatal surgery) might conceivably increase the risk of thermal stress and thus body overheating. Here, we assessed the efficacy of a polyethylene bag in infants assigned to wrap (W) or nonwrap (NW, control) groups during placement of a percutaneous vena cava catheter by applying a new mathematical model that calculates heat exchanges for covered and uncovered body segments...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28811165/dicyanomethylene-substituted-benzothiazole-squaraines-the-efficiency-of-photodynamic-therapy-in-vitro-and-in-vivo
#2
Yongbiao Wei, Xiaoxiao Hu, Luyao Shen, Bing Jin, Xiangjun Liu, Weihong Tan, Dihua Shangguan
The lack of ideal photosensitizers limits the clinicalapplication of photodynamic therapy (PDT). Here we report the PDT efficiency of dicyanomethylene substituted benzothiazole squaraine derivatives. This class of squaraine derivatives possess strong absorption and long excitation and emission wavelengths (ex/em, 685/720nm). They show negligible dark toxicity, but can generate singlet oxygen under irradiation resulting in the apoptosis and necrosis of cells (phototoxicity). Changing the side chains of these compounds greatly influences their albumin-binding rate, cellular uptake and their phototoxicity...
August 9, 2017: EBioMedicine
https://www.readbyqxmd.com/read/28808382/allium-sativum-constituents-exhibit-anti-tubercular-activity-in-vitro-and-in-raw-264-7-mouse-macrophage-cells-infected-with-mycobacterium-tuberculosis-h37rv
#3
Swapna S Nair, Sujay S Gaikwad, Savita P Kulkarni, Alka Pravin Mukne
BACKGROUND: Long duration of treatment, side-effects of currently used anti-tubercular drugs and emergence of drug-resistant forms of Mycobacterium tuberculosis (MTB) warrants the need to develop new drugs to tackle the scourge of tuberculosis (TB). Garlic is an edible plant reported to have anti-tubercular activity. However, previous researches on anti-tubercular effect of garlic were focused mostly on preliminary in vitro screening. OBJECTIVE: To identify constituents responsible for anti-tubercular activity of thiosulfinate-derivative rich extract of garlic (GE) and to evaluate activity of the most active constituent in RAW 264...
July 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28805680/broadband-ultra-deep-sub-diffraction-limit-optical-focusing-by-metallic-graded-index-mgrin-lenses
#4
Yechuan Zhu, Weizheng Yuan, Hao Sun, Yiting Yu
The development of techniques for efficiently confining energy in the visible and infrared spectral regions to the deep subwavelength spatial scale with dimensions as small as a few nanometers would have great significance for scientific research and engineering practices. Such an ability to manipulate light is impossible for conventional dielectric lenses due to the diffraction limit. Here, we propose a metallic graded-index (MGRIN) lens formed by an array of coupled metallic waveguides with identical nanoscale widths embedded by index-varying dielectrics to enable the optical nanofocusing...
August 12, 2017: Nanomaterials
https://www.readbyqxmd.com/read/28802090/assessment-of-the-dynamics-of-human-glymphatic-system-by-near-infrared-spectroscopy-nirs
#5
Teemu Myllylä, Markus Harju, Vesa Korhonen, Alexander Bykov, Vesa Kiviniemi, Igor Meglinski
Fluctuations in brain water content has attracted increasing interest, particularly as regards studies of the glymphatic system, which is connected with the complex organisation of dural lymphatic vessels, responsible for cleaning tissue. Disturbances of glymphatic circulation are associated with several brain disorders, including dementia. This paper introduces an approach to non-invasive measurement of water dynamics in the human brain utilizing near-infrared spectroscopy (NIRS). We demonstrate the possibility to sense dynamic variations of water content between the skull and grey matter, for instance, in the subarachnoid space...
August 12, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28801267/primum-non-nocere-the-effects-of-sodium-hypochlorite-on-dentin-as-used-in-endodontics
#6
Li-Sha Gu, Xue-Qing Huang, Brandon Griffin, Brian R Bergeron, David H Pashley, Li-Na Niu, Franklin R Tay
The medical literature is replete with the maxim 'primum non nocere', cautioning health care providers to avoid doing any harm to human subjects in their delivery of medical care. Sodium hypochlorite (NaOCl) is a well-established irrigant for root canal treatment because of its antimicrobial and organic tissue remnant dissolution capability. However, little is known about the deleterious effect of this strong oxidizing agent on the integrity of human mineralized dentin. Iatrogenically-induced loss of dentin integrity may precipitate post-treatment root fracture and has potential medico-legal complications...
August 8, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28801216/a-novel-process-for-separation-of-hazardous-poly-vinyl-chloride-from-mixed-plastic-wastes-by-froth-flotation
#7
Jianchao Wang, Hui Wang, Chongqing Wang, Lingling Zhang, Tao Wang, Long Zheng
A novel method, calcium hypochlorite (CHC) treatment, was proposed for separation of hazardous poly(vinyl chloride) (PVC) plastic from mixed plastic wastes (MPWs) by froth flotation. Flotation behavior of single plastic indicates that PVC can be separated from poly(ethylene terephthalate) (PET), poly(acrylonitrile-co-butadiene-co-styrene) (ABS), polystyrene (PS), polycarbonate (PC) and poly(methyl methacrylate) (PMMA) by froth flotation combined with CHC treatment. Mechanism of CHC treatment was examined by contact angle measurement, scanning electron microscopy, Fourier transform infrared and X-ray photoelectron spectroscopy...
August 8, 2017: Waste Management
https://www.readbyqxmd.com/read/28800445/enzyme-sensitive-gemcitabine-conjugated-albumin-nanoparticles-as-a-versatile-theranostic-nanoplatform-for-pancreatic-cancer-treatment
#8
Haijie Han, Jinhui Wang, Tingting Chen, Lichen Yin, Qiao Jin, Jian Ji
Development of gemcitabine (GEM) nanocarriers as theranostic agents for pancreatic cancer chemotherapy has received extensive attention in recent years. A novel enzyme-sensitive albumin-based GEM delivery nanoplatform was developed in this research by simple conjugation of GEM to human serum albumin (HSA) via cathepsin B cleavable peptide GFLG and then complexing with near-infrared (NIR) dye IR780, forming a HSA-GEM/IR780 complex. The successful preparation of HSA-GEM/IR780 complex was confirmed by Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry (MALDI-TOF-MS), UV-vis-NIR absorption spectra and fluorescent emission spectra...
July 17, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28795811/dispersion-of-multi-walled-carbon-nanotubes-by-polymers-with-carbazole-pendants
#9
Caizhen Liang, Bin Wang, Jianjun Chen, Qiwen Yong, Yuewen Huang, Bing Liao
The block copolymers poly(4-(N-carbazolyl)methyl styrene-bl-poly (ethylene glycol) methyl ether methacrylate) (PCMSm-b-PAPEGn) and homopolymer PCMS30 synthesized by RAFT polymerization were used to disperse multi-walled carbon nanotubes (MWCNTs). To probe the adsorption and dispersion ability of polymers, characterization analysis of MWCNT dispersions was evaluated by Fourier transform infrared, X-ray photoelectron spectroscopic, transmission electron microscopy, ultraviolet-visible spectroscopic and thermogravimetric analysis...
August 10, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28792958/can-remote-infrared-cameras-be-used-to-differentiate-small-sympatric-mammal-species-a-case-study-of-the-black-tailed-dusky-antechinus-antechinus-arktos-and-co-occurring-small-mammals-in-southeast-queensland-australia
#10
Emma L Gray, Todd E Dennis, Andrew M Baker
The black-tailed dusky antechinus (Antechinus arktos) is an endangered, small carnivorous marsupial endemic to Australia, which occurs at low population density along with abundant sympatric populations of other small mammals: Antechinus stuartii, Rattus fuscipes and Melomys cervinipes. Using A. arktos as a model species, we aimed to evaluate the effectiveness of infrared digital camera traps for detecting and differentiating small mammals and to comment on the broad applicability of this methodology. We also sought to understand how the detection probabilities of our target species varied over time and characterize their activity patterns...
2017: PloS One
https://www.readbyqxmd.com/read/28792746/superacid-surfactant-exchange-enabling-nondestructive-dispersion-of-full-length-carbon-nanotubes-in-water
#11
Peng Wang, Mijin Kim, Zhiwei Peng, Chuan-Fu Sun, Jasper Mok, Anna Lieberman, YuHuang Wang
Attaining aqueous solutions of individual, long single-walled carbon nanotubes is a critical first step for harnessing the extraordinary properties of these materials. However, the widely used ultrasonication-ultracentrifugation approach and its variants inadvertently cut the nanotubes into short pieces. The process is also time-consuming and difficult to scale. Here we present an unexpectedly simple solution to this decade-old challenge by directly neutralizing a nanotube-chlorosulfonic acid solution in the presence of sodium deoxycholate...
August 16, 2017: ACS Nano
https://www.readbyqxmd.com/read/28783593/amplification-of-near-infrared-fluorescence-in-semiconducting-polymer-nanoprobe-for-grasping-the-behaviors-of-systemically-administered-endothelial-cells-in-ischemia-treatment
#12
Duo Mao, Jie Liu, Shenglu Ji, Ting Wang, Yu Hu, Donghui Zheng, Renqiang Yang, Deling Kong, Dan Ding
To date, there have been few studies on using fluorescent cell trackers for non-invasively monitoring the in vivo fate of systemically administered cells. This is because only a relatively small number of cells can reach the disease site post systemic infusion, and thus achieving ideal in vivo cell tracking requires that the fluorescent cell trackers should hold combined merits of ultrahigh near-infrared (NIR) fluorescence, negligible interference on cell behavior and function, excellent retention within cells, as well as accurate long-term cell tracking ability...
August 2, 2017: Biomaterials
https://www.readbyqxmd.com/read/28783494/degradation-of-polyvinyl-alcohol-pva-by-uv-chlorine-oxidation-radical-roles-influencing-factors-and-degradation-pathway
#13
Bei Ye, Yue Li, Zhuo Chen, Qian-Yuan Wu, Wen-Long Wang, Ting Wang, Hong-Ying Hu
Polyvinyl alcohol (PVA) is widely used in industry but is difficult to degrade. In this study, the synergistic effect of UV irradiation and chlorination on degradation of PVA was investigated. UV irradiation or chlorination alone did not degrade PVA. By contrast, UV/chlorine oxidation showed good efficiency for PVA degradation via generation of active free radicals, such as OH and Cl. The relative importance of these two free radicals in the oxidation process was evaluated, and it was shown that OH contributed more to PVA degradation than Cl did...
May 30, 2017: Water Research
https://www.readbyqxmd.com/read/28783182/the-effect-of-hydrate-promoters-on-gas-uptake
#14
Chun-Gang Xu, Yi-Song Yu, Ya-Long Ding, Jing Cai, Xiao-Sen Li
Gas hydrate technology is considered as a promising technology in the fields of gas storage and transportation, gas separation and purification, seawater desalination, and phase-change thermal energy storage. However, to date, the technology is still not commercially used mainly due to the low gas hydrate formation rate and the low gas uptake. In this study, the effect of hydrate promoters on gas uptake was systematically studied and analyzed based on hydrate-based CH4 storage and CO2 capture from CO2/H2 gas mixture experiments...
August 16, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28782566/small-monomeric-and-highly-stable-near-infrared-fluorescent-markers-derived-from-the-thermophilic-phycobiliprotein-apcf2
#15
Wen-Long Ding, Dan Miao, Ya-Nan Hou, Su-Ping Jiang, Bao-Qin Zhao, Ming Zhou, Hugo Scheer, Kai-Hong Zhao
Biliproteins have extended the spectral range of fluorescent proteins into the region of maximal transmission of most tissues and are favorable for multiplexing, but their application presents considerable challenges. Their fluorescence derives from open-chain tetrapyrrole chromophores which often require the introduction of dedicated reductases and lyases. In addition, their fluorescence yield generally decreases with increasing wavelengths and depends strongly on the state of the binding protein. We report fluorescent biliproteins, termed BDFPs, that are derived from the phycobilisome core subunit, ApcF2: this subunit is induced in the thermophilic cyanobacterium, Chroococcidiopsis thermalis, by far-red light and binds phycocyanobilin non-covalently...
August 3, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28780598/optimization-of-monomethoxy-polyethyleneglycol-modified-oxalate-decarboxylase-by-response-surface-methodology
#16
Han Long, XingHua Cai, Hui Yang, JunBin He, Jia Wu, RiHui Lin
In order to improve the stability of oxalate decarboxylase (Oxdc), response surface methodology (RSM), based on a four-factor three-level Box-Behnken central composite design was used to optimize the reaction conditions of oxalate decarboxylase (Oxdc) modified with monomethoxy polyethyleneglycol (mPEG5000). Four independent variables such as the ratio of mPEG-aldehyde to Oxdc, reaction time, temperature, and reaction pH were investigated in this work. The structure of modified Oxdc was identified by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and Fourier transform infrared (FTIR) spectroscopy, the stability of the modified Oxdc was also investigated...
August 5, 2017: Journal of Biological Physics
https://www.readbyqxmd.com/read/28779887/small-plastic-debris-in-sediments-from-the-central-adriatic-sea-types-occurrence-and-distribution
#17
Michele Mistri, Vanessa Infantini, Marco Scoponi, Tommaso Granata, Letizia Moruzzi, Francesca Massara, Miriam De Donati, Cristina Munari
This is the first survey to investigate the occurrence and extent of microplastic contamination in sediments collected along a coast-open sea 140km-long transect in the Central Adriatic Sea. Plastic debris extracted from 64 samples of sediments were counted, weighted and identified by Fourier-transform infrared spectroscopy (FT-IR). Several types of plastic particles were observed in 100% of the stations. Plastic particles ranged from 1 to 30mm in length. The primary shape types by number were filaments (69...
August 2, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28776488/amino-functionalized-mesoporous-silica-nanoparticles-as-efficient-carriers-for-anticancer-drug-delivery
#18
Yongju He, Liangyu Luo, Shuquan Liang, Mengqiu Long, Hui Xu
Amino-functionalized mesoporous silica nanoparticles (MSN-NH2) were synthesized by a post-grafting method and further studied as carriers for doxorubicin hydrochloride (DOX) delivery. The morphology, structure, and property of MSN-NH2 and DOX-loaded MSN-NH2 (DOX@MSN-NH2) were studied using various techniques, such as transmission electron microscopy, Fourier transformed infrared spectroscopy, N2 adsorption-desorption isotherms, and zeta potentials. The drug loading and release profile as well as the in vitro cell cytotoxicity were detaily investigated...
January 1, 2017: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/28776408/long-term-results-of-a-randomized-controlled-double-blind-study-of-low-level-laser-therapy-before-exercises-in-knee-osteoarthritis-laser-and-exercises-in-knee-osteoarthritis
#19
Patrícia Pereira Alfredo, Jan Magnus Bjordal, Washington Steagall Junior, Rodrigo Álvaro Brandão Lopes Martins, Martin B Stausholm, Raquel Aparecida Casarotto, Amélia Pasqual Marques, Jon Joensen
OBJECTIVES: To assess the long-term effects of low-level laser therapy (LLLT), in combination with strengthening exercises in patients with osteoarthritis of the knee. DESIGN: Follow-up results at three and six months in a previously published randomized, double-blind, placebo-controlled trial. SETTING: Specialist Rehabilitation Services. SUBJECTS: Forty participants of both genders, aged 50-75 years with knee osteoarthritis grade 2-4 on Kellgren-Lawrence scale...
August 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28773956/pentaethylenehexamine-loaded-hierarchically-porous-silica-for-co%C3%A2-adsorption
#20
Changchun Ji, Xin Huang, Lei Li, Fukui Xiao, Ning Zhao, Wei Wei
Recently, amine-functionalized materials as a prospective chemical sorbent for post combustion CO₂ capture have gained great interest. However, the amine grafting for the traditional MCM-41, SBA-15, pore-expanded MCM-41 or SBA-15 supports can cause the pore volume and specific surface area of sorbents to decrease, significantly affecting the CO₂ adsorption-desorption dynamics. To overcome this issue, hierarchical porous silica with interparticle macropores and long-range ordering mesopores was prepared and impregnated with pentaethylenehexamine...
October 15, 2016: Materials
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