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Joseph A Gil, Gregory R Waryasz, Walter Klyce, Alan H Daniels
Neurogenic heterotopic ossification (NHO) involves deposition of bone in extraskeletal tissue in the setting of a neurological disorder, and its pathophysiology is incompletely understood. NHO can lead to significant disability and functional impairment. NHO initially manifests as pain and joint stiffness. Early diagnosis requires appropriate suspicion and imaging studies to detect the uncalcified collagen matrix that forms in the early stages of NHO. If diagnosis is made in the early phase of NHO, progression may be halted with bisphosphonates, indomethacin or radiation therapy...
December 2015: Rhode Island Medical Journal
Stephen D Klyce, Marguerite B McDonald, Marco U Morales
PURPOSE: To explore the use of microperimetry in the evaluation of macular dysfunction in patients with cataract, to aid in proper intraocular lens selection (multifocal vs monofocal), and to set expectations for postoperative visual function. METHODS: One randomly chosen eye of 10 patients diagnosed as having mild (1+) to moderate (3+) cataract was evaluated before and 1 week after cataract surgery with the MAIA microperimeter (Centervue S.p.A, Padova, Italy). Corrected distance visual acuity, dilated and undilated biomicroscopy and indirect fundus examinations, intraocular pressure measurement, and a MAIA microperimeter test to measure macular sensitivity and fixation pattern were also performed...
October 2015: Journal of Refractive Surgery
Daniel W Klyce, Charles H Bombardier, Trevor J Davis, Narineh Hartoonian, Jeanne M Hoffman, Jesse R Fann, Claire Z Kalpakjian
OBJECTIVE: To examine whether grief is a psychometrically sound construct that is distinct from depression in individuals who have recently sustained a spinal cord injury (SCI). DESIGN: Cross-sectional survey. SETTING: Inpatient rehabilitation units at 3 geographically diverse, university-affiliated medical centers. PARTICIPANTS: Patients with SCI (N=206) were recruited (163 men [79.1%]). Most patients were non-Hispanic whites (n=175 [85...
August 2015: Archives of Physical Medicine and Rehabilitation
Anastasios John Kanellopoulos, George Asimellis
PURPOSE: To investigate repeatability of steep and flat keratometry measurements, as well as astigmatism axis in cohorts with normal range and regular astigmatic such as: eyes following laser-assisted in situ keratomileusis (LASIK) and normal population, as well as cohorts of high and irregular astigmatism such as keratoconic eyes, and keratoconic eyes following corneal collagen cross-linking, employing a novel corneal reflection topography device. METHODS: Steep and flat keratometry and astigmatism axis measurement repeatability was investigated employing a novel multicolored-spot reflection topographer (Cassini) in four study groups, namely a post myopic LASIK-treated Group A, a keratoconus Group B, a post-CXL keratoconus Group C, and a control Group D of routine healthy patients...
2015: Clinical Ophthalmology
Susanne Goebels, Timo Eppig, Stefan Wagenpfeil, Alan Cayless, Berthold Seitz, Achim Langenbucher
PURPOSE: To derive limits of metric keratoconus indices for classification into keratoconus stages. DESIGN: Validity and reliability analysis of diagnostic tools. METHODS: A total of 126 patients from the keratoconus center of Homburg/Saar were evaluated with respect to Amsler criteria, using Pentacam (Keratoconus Index [KI], Topographic Keratoconus Classification [TKC]), Topographic Modeling System (Smolek/Klyce, Klyce/Maeda), and Ocular Response Analyzer (Keratoconus Match Probability [KMP], Keratoconus Match Index [KMI])...
April 2015: American Journal of Ophthalmology
J Bradley Randleman, Jihan Akhtar, Michael J Lynn, Renato Ambrósio, William J Dupps, Ronald R Krueger, Stephen D Klyce
PURPOSE: To compare objective and subjective metrics from regular and high-resolution Scheimpflug devices (Pentacam) to determine their equivalence and interchangeability for refractive surgery screening. SETTING: Emory Vision at Emory University, Atlanta, Georgia, USA. DESIGN: Retrospective comparative case series. METHODS: Eyes of consecutive screened refractive surgery patients were evaluated with high-resolution and regular Scheimpflug devices...
February 2015: Journal of Cataract and Refractive Surgery
Bence Lajos Kolozsvári, Goran Petrovski, Péter Gogolák, Éva Rajnavölgyi, Flóra Tóth, András Berta, Mariann Fodor
PURPOSE: To study the association between different types of mediators in the tear fluid and topographic indices characterizing the severity of keratoconus (KC). METHODS: In this study, nonstimulated tear fluid samples were collected from 14 eyes of 11 patients with KC. The following indices were measured by corneal topography: maximum K value, average K value, Klyce/Maeda keratoconus index (KCI), Smolek/Klyce keratoconus severity index, opposite sector index, center/surround index, keratoconus prediction index and standard deviation of corneal power...
2014: Ophthalmic Research
Isaac C Ramos, Rosane Correa, Frederico P Guerra, William Trattler, Michael W Belin, Stephen D Klyce, Bruno M Fontes, Paulo Schor, Michael K Smolek, Daniel G Dawson, Maria Regina Chalita, Jorge O Cazal, Milton Ruiz, J Bradley Randleman, Renato Ambrósio
PURPOSE: To evaluate the variability of subjective corneal topography map classification between different experienced examiners and the impact of changing from an absolute to a normative scale on the classifications. METHODS: Preoperative axial curvature maps using Scheimpflug imaging obtained with the Pentacam HR (Oculus Optikgeräte, Wetzlar, Germany) and clinical parameters were sent to 11 corneal topography specialists for subjective classification according to the Ectasia Risk Scoring System...
November 2013: Journal of Refractive Surgery
Elena Zemova, Timo Eppig, Berthold Seitz, Sergey Toropygin, Stefan Arnold, Achim Langenbucher, Stefan Gräber, Nóra Szentmáry
PURPOSE: To determine the interaction between corneal topographic and tomographic parameters and dry eye syndrome (DES) in keratoconus (KC) patients. METHODS: Seventy-seven eyes of 49 patients with KC (age 34.4 ± 11.6 years) were enrolled in this study. In these 77 eyes we recorded surface regularity index (SRI), surface asymmetry index (SAI) and Klyce/Maeda KC index (KCI) using the Topographic Modeling System (TMS-5, Tomey, Tennenlohe, Germany), Index of Surface Variance (ISV), Index of Vertical Asymmetry (IVA), KC Index (KI), Center KC Index (CKI), Index of Height Asymmetry (IHA) and Index of Height Decentration (IHD) using Pentacam (Pentacam HR, Oculus, Germany)...
January 2014: Current Eye Research
Stephen D Klyce
No abstract text is available yet for this article.
March 2013: Investigative Ophthalmology & Visual Science
George O Waring, Stephen D Klyce
No abstract text is available yet for this article.
2011: International Ophthalmology Clinics
Samantha L Backhaus, Summer L Ibarra, Daniel Klyce, Lance E Trexler, James F Malec
OBJECTIVE: To determine whether training in coping strategies will improve psychologic functioning and self-efficacy in survivors of brain injury (BI) and caregivers. DESIGN: Randomized controlled pilot study with measurements at baseline, postintervention, and 3-month follow-up. SETTING: Postacute rehabilitation clinic. PARTICIPANTS: Survivors of BI (n=20) and caregivers (n=20). INTERVENTIONS: The Brain Injury Coping Skills Group is a 12-session, manualized, cognitive-behavioral treatment (CBT) group providing psychoeducation, support, and coping skills training...
June 2010: Archives of Physical Medicine and Rehabilitation
Lance E Trexler, Laura C Trexler, James F Malec, Daniel Klyce, Devan Parrott
OBJECTIVE: To examine the impact of resource facilitation (RF) on return to work, participation in home and community activities, and depression. PARTICIPANTS: Twenty-two people with acquired brain injury (mean age = 43 years; mean education = 13.3 years). DESIGN: A prospective randomized controlled trial of RF compared with standard care. All participants received standard follow-up services, but participants in the RF group were also assigned a resource facilitator to assist them in returning to work...
November 2010: Journal of Head Trauma Rehabilitation
Paolo Vinciguerra, Elena Albè, Silvia Trazza, Theo Seiler, Daniel Epstein
OBJECTIVES: To report intraoperative and 24-month refractive, topographic, tomographic, and aberrometric outcomes after corneal collagen cross-linking in progressive advanced keratoconus. METHODS: Prospective, nonrandomized single-center clinical study involving 28 eyes. Main outcome measures included uncorrected and best spectacle-corrected visual acuities, sphere and cylinder refraction, topography, tomography, aberrometry, and endothelial cell count evaluated at baseline and follow-up at 1, 3, 6, 12, and 24 months after treatment...
October 2009: Archives of Ophthalmology
Paolo Vinciguerra, Fabrizio I Camesasca, Elena Albè, Silvia Trazza
PURPOSE: To evaluate the 1-year results of corneal collagen cross-linking (CXL) in eyes with postoperative excimer laser refractive surgery corneal ectasia. METHODS: Thirteen eyes of 9 consecutive patients who had undergone excimer laser refractive surgery (photorefractive keratectomy [n = 3], LASIK [n = 10]) with resultant unstable corneal ectasia underwent CXL with photosensitizing riboflavin 0.1% solution and subsequent exposure to ultraviolet radiation. Study eyes underwent complete ophthalmologic examination, endothelial specular microscopy, corneal topography, and aberrometry as well as central pachymetry and Scheimpflug-based topo/tomography preoperatively and at 3-, 6-, and 12-month intervals...
July 2010: Journal of Refractive Surgery
Stephen D Klyce
No abstract text is available yet for this article.
July 2009: British Journal of Ophthalmology
Paolo Vinciguerra, Elena Albè, Silvia Trazza, Pietro Rosetta, Riccardo Vinciguerra, Theo Seiler, Dan Epstein
PURPOSE: To report refractive, topographic, tomographic, and aberrometric outcomes 12 months after corneal cross-linking (CXL) in eyes with progressive advanced keratoconus. DESIGN: Prospective, nonrandomized, single-center clinical study. PARTICIPANTS: Twenty-eight eyes undergoing CXL between April and June 2006. INTERVENTION: Riboflavin-ultraviolet A (UVA)-induced CXL included instillation of 0.1% riboflavin-20% dextrane solution 30 minutes before UVA irradiation and every 5 minutes for an additional 30 minutes during irradiation...
March 2009: Ophthalmology
Michael K Smolek, Stephen D Klyce
PURPOSE: Wavefront data are expressed in micrometers and referenced to the pupil plane, but current methods to map wavefront error lack standardization. Many use normalized or floating scales that may confuse the user by generating ambiguous, noisy, or varying information. An absolute scale that combines consistent clinical information with statistical relevance is needed for wavefront error mapping. The color contours should correspond better to current corneal topography standards to improve clinical interpretation...
November 2007: Ophthalmology
Stephen D Klyce
No abstract text is available yet for this article.
August 2007: British Journal of Ophthalmology
Juan Tabernero, Stephen D Klyce, Edwin J Sarver, Pablo Artal
PURPOSE: When keratorefractive surgery is used to treat a central corneal diameter smaller than the resting pupil, visual symptoms of polyopia, ghosting, blur, haloes, and glare can be experienced. Progress has been made to enlarge the area of surgical treatment to extend beyond the photopic pupil; however, geometric limitations can pose restrictions to extend the treatment beyond the mesopic pupil diameter and can lead to impediments in night vision. The size of the treated area that has achieved good optical performance has been defined as the functional optical zone (FOZ)...
March 2007: Investigative Ophthalmology & Visual Science
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