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https://www.readbyqxmd.com/read/27859979/diabetes-conflict-outstrips-the-positive-impact-of-self-efficacy-on-youth-adherence-and-glycemic-control-in-type-1-diabetes
#1
Amy E Noser, Lindsay Huffhines, Mark A Clements, Susana R Patton
OBJECTIVE: To examine whether self-efficacy buffers the deleterious consequences of diabetes-specific family conflict on self-monitoring blood glucose (SMBG) and glycated hemoglobin (HbA1c) in youth with type 1 diabetes mellitus (T1DM). METHODS: A total of 129 youth with T1DM (aged 10-16 years) completed measures of diabetes-specific family conflict and self-efficacy for diabetes management, and their blood glucose meter data and HbA1c were extracted from the electronic medical record...
November 17, 2016: Pediatric Diabetes
https://www.readbyqxmd.com/read/27834578/serum-adiponectin-levels-and-cardiorespiratory-fitness-in-non-overweight-and-overweight-portuguese-adolescents-the-labmed-physical-activity-study
#2
César Agostinis-Sobrinho, Carla Moreira, Sandra Abreu, Luis Lopes, José Oliveira-Santos, Jostein Steene-Johannessen, Jorge Mota, Rute Santos
PURPOSE: This study examined the independent associations between cardiorespiratory fitness and circulating adiponectin concentration in adolescents, controlling for several potential covariates. METHODS: This is a cross-sectional study in Portuguese adolescents. A sample of 529 (267 girls) aged 12-18 years were included and categorized as overweight and non-overweight. Cardiorespiratory fitness was assessed by 20 meters shuttle run test. We measured serum adiponectin, high-sensitivity C-reactive protein, fasting glucose, insulin and HDL-cholesterol...
November 11, 2016: Pediatric Exercise Science
https://www.readbyqxmd.com/read/27808326/one-pot-bioinspired-synthesis-of-all-inclusive-protein-protein-nanoflowers-for-point-of-care-bioassay-detection-of-e-coli-o157-h7-from-milk
#3
Ranfeng Ye, Chengzhou Zhu, Yang Song, Junhua Song, Shaofang Fu, Qian Lu, Xu Yang, Mei-Jun Zhu, Dan Du, He Li, Yuehe Lin
Protein-protein conjugates play a vital role in bioassays with their inherent functions of biological recognition and signal amplification. Herein, a one-pot green method for synthesis of all-inclusive protein-protein nanoflowers has been developed. The protein-protein nanoflowers integrate both essential functions of biological recognition and signal amplification, and they were used as ideal signal labels for the sensitive point-of-care detection of Escherichia coli O157:H7. Especially noteworthy, the prepared Con A-invertase-CaHPO4 hybrid nanoflowers simultaneously loaded sufficient invertase and enhanced the activity of the immobilized invertase, which fits well with the requirements of signal labels for bioassays...
December 7, 2016: Nanoscale
https://www.readbyqxmd.com/read/27758706/self-monitoring-of-blood-glucose-among-patients-with-type-2-diabetes-mellitus-in-eastern-nigeria-need-for-multi-strategic-interventions
#4
Ejiofor T Ugwu, Casmir Jg Orjioke, Ekenechukwu E Young
BACKGROUND: Self monitoring of blood glucose (SMBG) is a useful adjunct to lifestyle modification and medications for optimal management of type 2 diabetes mellitus (DM). This study was aimed at evaluating the practice, cost and associations of SMBG in subjects with type 2 DM in Enugu, Nigeria. METHODS: In a cross-sectional survey conducted at the diabetes clinic in three hospitals, 366 type 2 diabetic subjects aged 18-65 years were consecutively interviewed. Socio-demographic and clinical information were documented and glycated hemoglobin was performed for all the participants...
October 14, 2016: Current Diabetes Reviews
https://www.readbyqxmd.com/read/27749114/successful-performance-of-laboratory-investigations-with-blood-glucose-meters-employing-a-dynamic-electrochemistry-based-correction-algorithm-is-dependent-on-careful-sample-handling
#5
Filiz Demircik, David Klonoff, Petra B Musholt, Sanja Ramljak, Andreas Pfützner
BACKGROUND: Devices employing electrochemistry-based correction algorithms (EBCAs) are optimized for patient use and require special handling procedures when tested in the laboratory. This study investigated the impact of sample handling on the results of an accuracy and hematocrit interference test performed with BG*Star, iBG*Star; OneTouch Verio Pro and Accu-Chek Aviva versus YSI Stat 2300. METHODS: Venous heparinized whole blood was manipulated to contain three different blood glucose concentrations (64-74, 147-163, and 313-335 mg/dL) and three different hematocrit levels (30%, 45%, and 60%)...
October 2016: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/27739331/large-scale-performance-evaluation-of-accu-chek-inform-ii-point-of-care-glucose-meters
#6
Tae-Dong Jeong, Eun-Jung Cho, Dae-Hyun Ko, Woochang Lee, Sail Chun, Ki-Sook Hong, Won-Ki Min
BACKGROUND: The aim of this study was to report the experience of large-scale performance evaluation of 238 Accu-Chek Inform II point-of-care (POC) glucose meters in a single medical setting. METHODS: The repeatability of 238 POC devices, the within-site imprecision of 12 devices, and the linearity of 49 devices were evaluated using glucose control solutions. The glucose results of 24 POC devices and central laboratory were compared using patient samples. RESULTS: Mean concentration of control solutions was 2...
December 2016: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/27697848/comparative-accuracy-of-17-point-of-care-glucose-meters
#7
Laya Ekhlaspour, Debbie Mondesir, Norman Lautsch, Courtney Balliro, Mallory Hillard, Kendra Magyar, Laura Goergen Radocchia, Aryan Esmaeili, Manasi Sinha, Steven J Russell
BACKGROUND: The accuracy of point-of-care blood glucose (BG) meters is important for the detection of dysglycemia, calculation of insulin doses, and the calibration of continuous glucose monitors. The objective of this study was to compare the accuracy of commercially available glucose meters in a challenging laboratory study using samples with a wide range of reference BG and hemoglobin values. METHODS: Fresh, discarded blood samples from a hospital STAT laboratory were either used without modification, spiked with a glucose solution, or incubated at 37°C to produce 347 samples with an even distribution across reference BG levels from 20 to 440 mg/dl and hemoglobin values from 9 to 16 g/dl...
October 3, 2016: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/27690486/psychology-technology-and-diabetes-management
#8
Linda A Gonder-Frederick, Jaclyn A Shepard, Jesse H Grabman, Lee M Ritterband
Use of technology in diabetes management is rapidly advancing and has the potential to help individuals with diabetes achieve optimal glycemic control. Over the past 40 years, several devices have been developed and refined, including the blood glucose meter, insulin pump, and continuous glucose monitor. When used in tandem, the insulin pump and continuous glucose monitor have prompted the Artificial Pancreas initiative, aimed at developing control system for fully automating glucose monitoring and insulin delivery...
October 2016: American Psychologist
https://www.readbyqxmd.com/read/27683538/emerging-and-disruptive-technologies
#9
Larry J Kricka
Several emerging or disruptive technologies can be identified that might, at some point in the future, displace established laboratory medicine technologies and practices. These include increased automation in the form of robots, 3-D printing, technology convergence (e.g., plug-in glucose meters for smart phones), new point-of-care technologies (e.g., contact lenses with sensors, digital and wireless enabled pregnancy tests) and testing locations (e.g., Retail Health Clinics, new at-home testing formats), new types of specimens (e...
August 2016: EJIFCC
https://www.readbyqxmd.com/read/27660634/tityus-serrulatus-envenoming-in-non-obese-diabetic-mice-a-risk-factor-for-severity
#10
Guilherme Honda de Oliveira, Felipe Augusto Cerni, Iara Aimê Cardoso, Eliane Candiani Arantes, Manuela Berto Pucca
BACKGROUND: In Brazil, accidents with venomous animals are considered a public health problem. Tityus serrulatus (Ts), popularly known as the yellow scorpion, is most frequently responsible for the severe accidents in the country. Ts envenoming can cause several signs and symptoms classified according to their clinical manifestations as mild, moderate or severe. Furthermore, the victims usually present biochemical alterations, including hyperglycemia. Nevertheless, Ts envenoming and its induced hyperglycemia were never studied or documented in a patient with diabetes mellitus (DM)...
2016: Journal of Venomous Animals and Toxins Including Tropical Diseases
https://www.readbyqxmd.com/read/27645817/critical-care-glucose-point-of-care-testing
#11
S N Narla, M Jones, K L Hermayer, Y Zhu
Maintaining blood glucose concentration within an acceptable range is a goal for patients with diabetes mellitus. Point-of-care glucose meters initially designed for home self-monitoring in patients with diabetes have been widely used in the hospital settings because of ease of use and quick reporting of blood glucose information. They are not only utilized for the general inpatient population but also for critically ill patients. Many factors affect the accuracy of point-of-care glucose testing, particularly in critical care settings...
2016: Advances in Clinical Chemistry
https://www.readbyqxmd.com/read/27630249/regulation-catches-up-to-reality-nonadjunctive-use-of-continuous-glucose-monitoring-data
#12
Steven V Edelman
The FDA recently conducted an Advisory Panel meeting to evaluate the safety, efficacy, and benefits of granting a nonadjunctive label claim for the DEXCOM G5 Mobile continuous glucose monitoring (CGM) system. If approved, this claim will allow users to make day-to-day treatment decisions, including insulin dosing directly from the glucose values and rate of changes arrows generated by the CGM device, without the requirement of a confirmatory measurement with a self-monitoring blood glucose (SMBG) meter. Sporadic SMBG testing gives limited data, while CGM gives a value every 5 minutes and has alerts, alarms, trending information and allows caregivers to follow the user in real time 24/7...
September 13, 2016: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/27625706/brazilian-multicenter-study-for-the-evaluation-of-patients-satisfaction-of-blood-glucose-self-monitoring-with-bgstar-%C3%A2-blood-glucose-meter-in-insulinized-patients-with-diabetes-mellitus-type-1-and-2
#13
Miguel Nasser Hissa
BACKGROUND: Diabetes mellitus (DM) is considered a global epidemic, and patient self-management education and support are critical in preventing and reducing the risk of complications. Self-monitoring of blood glucose (SMBG) is essential for care of individuals with DM, helping patients to achieve and maintain target blood glucose levels. The purpose of this study is to compare the satisfaction of insulinized DM patients on SMBG with use of investigational blood glucose meter (BGM) versus their routine device...
2016: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/27611472/magnetic-bead-liposome-hybrids-enable-sensitive-and-portable-detection-of-dna-methyltransferase-activity-using-personal-glucose-meter
#14
Youna Zhang, Qingwang Xue, Jifeng Liu, Huaisheng Wang
DNA methyltransferase (MTase) plays a critical role in maintaining genome methylation patterns, which has a close relationship to cancer and bacterial diseases. This encouraged the need to develop highly sensitive, simple, and robust assays for DNA MTase detection and inhibitor screening. Herein, a simple, sensitive, and specific DNA MTase activity assay was developed based on magnetic beads-liposome hybrids combined with personal glucose meter (PGM) for quantitative detection of DNA MTase and inhibitor screening...
August 30, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27605594/use-of-color-range-indicator-technology-on-point-of-care-meters-may-ease-self-management-of-blood-glucose
#15
Marc C Torjman
The study by Grady et al is timely and exciting striving toward better understanding of relevant human factors in the design of their glucose meter displays. Their investigation focused on meaningful device optimization objectives that could be important to improving diabetes self-management. Grady et al are to be complimented for their development of a PC-based computer simulator to further our understanding of how patients interpret their glucose meter readings. What is interesting is that important, and hopefully more appropriate decisions, can be made daily or hourly when a meter is capable of displaying the most relevant information in a manner that will prompt the user toward more favorable glucose management decisions...
November 2016: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/27605592/a-comprehensive-performance-evaluation-of-five-blood-glucose-systems-in-the-hypo-eu-and-hyperglycemic-range
#16
Eric Zijlstra, Lutz Heinemann, Annelie Fischer, Christoph Kapitza
BACKGROUND: The objective was to evaluate the performance (in terms of accuracy, precision, and trueness) of 5 CE-certified and commercially available blood glucose (BG) systems (meters plus test strips) using an innovative clinical-experimental study design with a 3-step glucose clamp approach and frequent capillary BG measurements. METHODS: Sixteen subjects with type 1 diabetes participated in this open label, single center trial. BG was clamped at 3 levels for 60 minutes each: 60-100-200 mg/dL...
November 2016: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/27605000/clinical-review-the-misreporting-of-logbook-download-and-verbal-self-measured-blood-glucose-in-adults-and-children-with-type-i-diabetes
#17
Miranda Blackwell, Benjamin J Wheeler
Despite advances in technology, the frequent self-measurement of blood glucose (SMBG) remains fundamental to the management of 1 diabetes mellitus (T1DM). Once measured, SMBG results are routinely reported back to health professionals and other interested parties, either verbally, via a logbook, or electronically downloaded from a pump or meter. The misreporting of SMBG using various techniques represents a classic non-adherence behavior and carries with it both acute and chronic dangers. In addition, while this behavior appears very prevalent, many aspects remain largely unstudied...
September 7, 2016: Acta Diabetologica
https://www.readbyqxmd.com/read/27570855/the-bacterial-contamination-rate-of-glucose-meter-test-strips-in-the-hospital-setting
#18
Khalid A Al-Rubeaan, Amr T M Saeb, Dhekra M AlNaqeb, Hamid M AlQumaidi, Turki A AlMogbel
OBJECTIVES: To assess the rate of bacterial contamination of the multi-use vial and single-use packed glucose meter strips, and to identify the type and frequency of various bacterial contamination in different hospital wards. METHODS: This prospective observational study was conducted by a team from the Strategic Center for Diabetes Research in 7 general hospitals in the Central region of Saudi Arabia during the period from August to September 2014 to assess the bacterial contamination rate of the unused strips...
September 2016: Saudi Medical Journal
https://www.readbyqxmd.com/read/27565231/diagnosis-of-prediabetes-in-cats-glucose-concentration-cut-points-for-impaired-fasting-glucose-and-impaired-glucose-tolerance
#19
M K Reeve-Johnson, J S Rand, D Vankan, S T Anderson, R Marshall, J M Morton
Diabetes is typically diagnosed in cats once clinical signs are evident. Diagnostic criteria for prediabetes in cats have not been defined. The objective of the study was to establish methodology and cut points for fasting and 2-h blood glucose concentrations in healthy client-owned senior cats (≥8 yr) using ear/paw samples and a portable glucose meter calibrated for feline blood. Of the 78 cats, 27 were ideal (body condition score [BCS] 4 or 5 of 9), 31 overweight (BCS 6 or 7), and 20 obese (BCS 8 or 9); 19 were Burmese and 59 non-Burmese...
October 2016: Domestic Animal Endocrinology
https://www.readbyqxmd.com/read/27548574/estimation-of-an-accuracy-index-of-a-diagnostic-biomarker-when-the-reference-biomarker-is-continuous-and-measured-with-error
#20
Mixia Wu, Dianchen Zhang, Aiyi Liu
New biomarkers continue to be developed for the purpose of diagnosis, and their diagnostic performances are typically compared with an existing reference biomarker used for the same purpose. Considerable amounts of research have focused on receiver operating characteristic curves analysis when the reference biomarker is dichotomous. In the situation where the reference biomarker is measured on a continuous scale and dichotomization is not practically appealing, an index was proposed in the literature to measure the accuracy of a continuous biomarker, which is essentially a linear function of the popular Kendall's tau...
August 22, 2016: Journal of Biopharmaceutical Statistics
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