keyword
https://read.qxmd.com/read/38718634/all-printed-wearable-biosensor-based-on-mwcnt-iron-oxide-nanocomposite-ink-for-physiological-level-detection-of-glucose-in-human-sweat
#1
JOURNAL ARTICLE
Chandradas Shamili, Adarsh Sivan Pillai, S Saisree, Achu Chandran, Manoj Raama Varma, Surendran Kuzhichalil Peethambharan
Wearable sensors for sweat glucose monitoring are gaining massive interest as a patient-friendly and non-invasive way to manage diabetes. The present work offers an alternative on-body method employing an all-printed flexible electrochemical sensor to quantify the amount of glucose in human sweat. The working electrode of the glucose sensor was printed using a custom-formulated ink containing multi-walled carbon nanotube (MWCNT), poly (3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOPT: PSS), and iron (II, III) oxide (Fe3 O4 ) nanoparticles...
May 4, 2024: Biosensors & Bioelectronics
https://read.qxmd.com/read/38713050/-erratum-in-point-of-care-blood-glucose-testing-post-market-performance-assessment-of-the-accu-chek-inform-ii-hospital-use-glucose-meter-doi-10-26442-00403660-2023-12-202522
#2
JOURNAL ARTICLE
E E Petryaykina, N A Mayanskiy, E S Demina, I V Karamysheva, K A Gorst, A V Timofeev
In the article "Point-of-care blood glucose testing: post-market performance assessment of the Accu-Chek Inform II hospital-use glucose meter," published in the Terapevticheskii Arkhiv journal, Vol. 95, No.12, 2023 (DOI: 10.26442/00403660.2023.12.202522), errors were made: the term "measurements at the place of treatment" was changed, as well as the section "Conflict of interest." At the request of the authors' team, errors in the conflict of interest and the wording of the term have been corrected, and the section "Information about the authors" has been updated...
April 16, 2024: Terapevticheskiĭ Arkhiv
https://read.qxmd.com/read/38712890/nutrition-support-carbohydrate-feeding-and-insulin-sensitivity-in-the-critically-ill-patient-a-complex-relationship
#3
JOURNAL ARTICLE
Ra'eesa Doola, Claire Dupuis, Jean-Charles Preiser
PURPOSE OF REVIEW: This review aims to summarize recent studies that highlight the complex relationship between nutrition, carbohydrate, insulin provision and glycaemic control in the critically ill patient population. RECENT FINDINGS: Results of observational studies concur to support early hypoglycaemia and persisting hyperglycaemia as life-threatening events. In contrast, interventional studies indicate that early macronutrient restriction appears to reduce the benefits related to insulin therapy...
May 8, 2024: Current Opinion in Clinical Nutrition and Metabolic Care
https://read.qxmd.com/read/38692264/commissioning-of-the-first-hospital-based-pet-radiopharmaceutical-cyclotron-in-greece-personnel-dose-assessment
#4
JOURNAL ARTICLE
S P Ioannidou, M Katsouli, E Doika
The role of positron emission tomography (PET) imaging with 2-fluoro-2-deoxy-D-glucose (FDG) is well established in the diagnosis and management of cancer patients. As the demand for PET imaging continues to rise, many hospitals are installing on-site self-shielded mini cyclotrons to produce their own radiopharmaceuticals, including FDG. In May 2021, the Dose-on-Demand Biomarker Generator (BG-75) was installed at the Metaxa Cancer Hospital in Greece, making it the first hospital-based PET radiopharmaceutical cyclotron in the country...
May 1, 2024: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://read.qxmd.com/read/38690155/differences-in-glucose-readings-between-the-continuous-glucose-monitoring-calibration-free-interstitial-sensors-versus-capillary-blood-glucose-monitoring-by-glucometer-an-analysis-of-two-cases
#5
JOURNAL ARTICLE
Phaik Ling Quah, Sally Mun Hua Chai, Kok Hian Tan
AIM: To assess the differences in glucose readings between the continuous glucose monitoring calibration-free interstitial sensors versus capillary blood glucose monitoring by glucometer. STUDY DESIGN: Two healthy non-pregnant volunteers participated in the study, and wore simultaneously both the calibration-free Freestyle Libre and the Dexcom G6 sensor. Glucose values were recorded before and after meals during breakfast, lunch, and dinner on three separate days by either scanning the Freestyle Libre CGM sensor with a smartphone, or obtaining glucose readings real-time through the Dexcom G6 CLARITY mobile application...
June 2024: Metabolism open
https://read.qxmd.com/read/38687846/psychometric-validation-of-the-hyperglycaemia-avoidance-scale-uk-has-uk
#6
JOURNAL ARTICLE
Vicky McKechnie, Shaila Khan, Rob Saunders, Stephanie A Amiel, Linda A Gonder-Frederick, Nick Oliver
AIMS: Hyperglycaemia aversion in type 1 diabetes can be associated with severe hypoglycaemia and impaired awareness of hypoglycaemia but is not routinely assessed clinically. This study aimed to undertake the first psychometric validation of the UK version of the Hyperglycaemia Avoidance Scale (HAS-UK). METHODS: The HAS-UK was completed by adults with type 1 diabetes in three separate research studies. Psychometric properties were evaluated, using exploratory factor analysis, internal consistency, and convergent validity...
April 30, 2024: Diabetic Medicine: a Journal of the British Diabetic Association
https://read.qxmd.com/read/38687277/sucrose-powered-liposome-nanosensors-for-urinary-glucometer-based-monitoring-of-cancer
#7
JOURNAL ARTICLE
Dongtao Zhou, Zhibin Zhang, Liqing Pan, Yanyi Wang, Jingjing Yang, Yanfeng Gao, Yujun Song
Timely detection of early-stage cancer holds immense potential in enhancing prognostic outcomes. There is an increasing desire for versatile tools to enable simple, sensitive, and cost-effective cancer detection. By exploiting the extraintestinal metabolic inertness and efficiency renal clearance of sucrose, we designed a liposome nanosensor using sucrose as a messenger to convert tumor-specific esterase activity into glucose meter readout, enabling economical and sensitive uri-nalysis for cancer detection in point-of-care testing (POCT)...
April 30, 2024: Angewandte Chemie
https://read.qxmd.com/read/38669074/proactive-identification-of-patients-with-diabetes-at-risk-of-uncontrolled-outcomes-during-a-diabetes-management-program-conceptualization-and-development-study-using-machine-learning
#8
JOURNAL ARTICLE
Arash Khalilnejad, Ruo-Ting Sun, Tejaswi Kompala, Stefanie Painter, Roberta James, Yajuan Wang
BACKGROUND: The growth in the capabilities of telehealth have made it possible to identify individuals with a higher risk of uncontrolled diabetes and provide them with targeted support and resources to help them manage their condition. Thus, predictive modeling has emerged as a valuable tool for the advancement of diabetes management. OBJECTIVE: This study aimed to conceptualize and develop a novel machine learning (ML) approach to proactively identify participants enrolled in a remote diabetes monitoring program (RDMP) who were at risk of uncontrolled diabetes at 12 months in the program...
April 26, 2024: JMIR Formative Research
https://read.qxmd.com/read/38667445/commutable-blood-materials-from-the-fixed-cell-method-for-performance-evaluation-of-blood-glucose-by-a-glucose-meter
#9
JOURNAL ARTICLE
Napaporn Apiratmateekul, Jintana Nammoonnoy, Gerald J Kost, Wanvisa Treebuphachatsakul
Glucose meters provide a rapid blood glucose status for evidence-based diagnosis, monitoring, and treatment of diabetes mellitus. We aimed to evaluate the commutability of processed blood materials (PBMs) and their use in the performance evaluation of glucose meters. Two PBMs obtained by the fixed-cell method were analyzed for homogeneity, stability, and commutability. The compatibility of ten pairs between mass spectrometry and each glucose meter was categorized as compatible (mean paired difference ≤ 5%) and incompatible (mean paired difference > 5%)...
April 11, 2024: Diagnostics
https://read.qxmd.com/read/38655033/lower-glycemia-levels-in-subjects-with-excessive-erythrocytosis-during-the-oral-glucose-tolerance-test-living-in-conditions-of-severe-hypoxia
#10
JOURNAL ARTICLE
Kely Melina Vilca Coaquira, Rossela Alejandra Rojas Chambilla, Jeancarlo Tejada Flores, Henry Oscar Tintaya Ramos, Mariela Mercedes Quispe Trujillo, Solanyela Anny Quispe Humpiri, Ángel Gabriel Calisaya Huacasi, Yony M Pino Vanegas, Gilberto Félix Peña Vicuña, Alberto Alcibiades Salazar Granara, Ana Lucia Tacuna Calderon, Nancy Monica Garcia Bedoya, Moua Yang, Ivan Hancco Zirena
BACKGROUND: Previous studies showed that residents of higher elevations have lower glucose levels. Our objective in this study is to determine the basal and postprandial glucose levels in apparently healthy permanent residents of the miner population center of La Rinconada located 5100 meters (m) above sea level. METHOD: Forty male permanent residents of the Rinconada miner population center were studied. The oral glucose tolerance test was used to evaluate basal and postprandial glycemia levels at 1, 2, and 3 h...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38621915/-mechanism-of-kuntai-capsules-in-treatment-of-polycystic-ovary-syndrome-rat-models-based-on-age-rage-signal-pathway
#11
JOURNAL ARTICLE
Jin-Ge Huang, Jian Zhang, Rui-Jun Xiang, Yuan-Yuan Wu, Tian-Yu He, Meng-Ni Zhao, Fang Wang
This study aims to investigate the impact of Kuntai Capsules(KTC) on polycystic ovarian syndrome(PCOS) rat models and explore the underlying mechanism. Fifty female SD rats were randomly divided into five groups(10 rats in each group), including control group, model group, low-, medium-, and high-dose KTC group. Except for the control group, the other groups were injected with dehydroepiandrosterone(DHEA) combined with a high-fat diet(HFD) to induce the PCOS rat model for 28 days. 0.315, 0.63, and 1.26 g·kg~(-1)·d~(-1) KTC was dissolved in the same amount of normal saline and given to low-, medium-, and high-dose KTC groups by gavage...
February 2024: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://read.qxmd.com/read/38551884/-insulin-treated-diabetes-in-general-practice
#12
JOURNAL ARTICLE
Bruno Guerci
DIABETES TEATED IN GENERAL PRACTICE. Blood glucose monitoring has been an integral part of diabetes treatment for many years, whether for type 1 diabetic patients on multiple daily injections of insulin, insulin pumps or artificial pancreas, and now for patients with type 2 diabetes, even without intnsified insulin therapy. Capillary blood glucose testing with glucose meters, developed in the 80s, has been largely replaced by continuous glucose monitoring with subcutaneous sensors, which since the early 2000s have revolutionized diabetes management, understanding and day-to-day monitoring, for patients and healthcare profressionals alike...
March 2024: La Revue du Praticien
https://read.qxmd.com/read/38534181/outdoor-artificial-light-at-night-and-reproductive-endocrine-and-glucose-homeostasis-and-polycystic-ovary-syndrome-in-women-of-reproductive-age
#13
JOURNAL ARTICLE
Lanlan Fang, Cong Ma, Guosheng Wang, Yongzhen Peng, Hui Zhao, Yuting Chen, Yubo Ma, Guoqi Cai, Yunxia Cao, Faming Pan
BACKGROUND: Artificial light at night, a well-recognized circadian clock disrupter, causes disturbances in endocrine homeostasis. However, the association of artificial light at night with polycystic ovary syndrome (PCOS) is still unknown. This study examines the effects of outdoor artificial light at night on sex hormones, glucose homeostasis markers, and PCOS prevalence in Anhui Province, China. METHODS: We recruited 20633 women of reproductive age from Anhui Medical University Reproductive Medicine Center...
March 22, 2024: Epidemiology
https://read.qxmd.com/read/38503121/a-universal-nucleic-acid-detection-platform-combing-crispr-cas12a-and-strand-displacement-amplification-with-multiple-signal-readout
#14
JOURNAL ARTICLE
Tian Li, Jinjin Wang, Jiaoyuan Fang, Fei Chen, Xinru Wu, Lan Wang, Meng Gao, Liping Zhang, Sanqiang Li
Rapid and sensitive detection of nucleic acids has become crucial in various fields. However, most current nucleic acid detection methods can only be used in specific scenarios, such as RT-qPCR, which relies on fluorometer for signal readout, limiting its application at home or in the field due to its high price. In this paper, a universal nucleic acid detection platform combing CRISPR/Cas12a and strand displacement amplification (CRISPR-SDA) with multiple signal readout was established to adapt to different application scenarios...
March 18, 2024: Talanta
https://read.qxmd.com/read/38502884/enhanced-interstitial-fluid-extraction-and-rapid-analysis-via-vacuum-tube-integrated-microneedle-array-device
#15
JOURNAL ARTICLE
Yuanting Xie, Jinhua He, Wenqing He, Tayyaba Iftikhar, Chuangjie Zhang, Lei Su, Xueji Zhang
Advancing the development of point-of-care testing (POCT) sensors that utilize interstitial fluid (ISF) presents considerable obstacles in terms of rapid sampling and analysis. Herein, an innovative strategy is introduced that involves the use of a 3D-printed, hollow microneedle array patch (MAP), in tandem with a vacuum tube (VT) connected through a hose, to improve ISF extraction efficiency and facilitate expedited analysis. The employment of negative pressure by the VT allows the MAP device to effectively gather ≈18 µL of ISF from the dermis of a live rabbit ear within a concise period of 5 min...
March 19, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://read.qxmd.com/read/38486754/age-appropriate-design-of-domestic-intelligent-medical-products-an-example-of-smart-blood-glucose-detector-for-the-elderly-with-ahp-qfd-joint-ke
#16
JOURNAL ARTICLE
Xiaojie Li, Hong Li
BACKGROUND: In response to the rise of intelligent products and the increasing prevalence of urban "empty nesters," we have developed a product specifically tailored for elderly diabetic patients. This product fulfils functional requirements and addresses stylistic preferences, contributing to the age-friendly evolution of home intelligent medical devices, particularly in intelligent blood glucose monitoring. METHODS: Our approach commenced with a comprehensive user experience analysis to ascertain the needs of elderly users regarding home blood glucose meters...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38463197/added-value-of-a-connected-glucose-meter-for-glycorrhachia-assessment
#17
JOURNAL ARTICLE
Laurent Blairon, Marie Tré-Hardy, Sophie Collignon, François Coenen, Ingrid Beukinga, Roberto Cupaiolo
OBJECTIVES: The aim of this study was to demonstrate the performance and added value of rapid glucose determination in cerebrospinal fluid using a connected glucometer. DESIGN AND METHODS: Intra-assay and inter-assay accuracies were calculated using residual clinical samples. Accuracies were measured by comparing the results obtained with the glucometer to those from the central laboratory on a large routine chemistry platform. RESULTS: The intra-assay coefficients of variation were between 6...
March 2024: Practical Laboratory Medicine
https://read.qxmd.com/read/38436046/ensuring-fidelity-key-elements-to-consider-in-disseminating-a-diabetes-telemanagement-program-for-underserved-hispanic-latinos-living-with-type-2-diabetes
#18
JOURNAL ARTICLE
Sabrina Martinez, Christian N Nouryan, Myia S Williams, Vidhi H Patel, Paulina Barbero, Valeria Correa Gomez, Jose Marino, Nicole Goris, Edgardo Cigaran, Dilcia Granville, Lawrence F Murray, Yael T Harris, Alyson Myers, Josephine Guzman, Amgad N Makaryus, Samy I McFarlane, Roman Zeltser, Maria Pena, Cristina Sison, Martin L Lesser, Myriam Kline, Ralph Joseph DiClemente, Renee Pekmezaris
BACKGROUND: The Hispanic/Latino population has greater risk (estimated >50%) of developing type 2 diabetes (T2D) and developing it at a younger age. The American Diabetes Association estimates costs of diagnosed diabetes in 2017 was $327 billion; with medical costs 2.3x higher than patients without diabetes. The purpose of this manuscript is to describe the methodology utilized in a randomized controlled trial aimed at evaluating the efficacy of a diabetes telemanagement (DTM) program for Hispanic/Latino patients with T2D...
2024: Front Clin Diabetes Healthc
https://read.qxmd.com/read/38428072/a-personal-glucose-meter-utilized-strategy-for-portable-and-label-free-detection-of-hydrogen-peroxide
#19
JOURNAL ARTICLE
Sangmo Lee, Hyoyong Kim, Junhyeok Yoon, Yong Ju, Hyun Gyu Park
Rapid and precise detection of hydrogen peroxide (H2 O2 ) holds great significance since it is linked to numerous physiological and inorganic catalytic processes. We herein developed a label-free and washing-free strategy to detect H2 O2 by employing a hand-held personal glucose meter (PGM) as a signal readout device. By focusing on the fact that the reduced redox mediator ([Fe(CN)6 ]4- ) itself is responsible for the final PGM signal, we developed a new PGM-based strategy to detect H2 O2 by utilizing the target H2 O2 -mediated oxidation of [Fe(CN)6 ]4- to [Fe(CN)6 ]3- in the presence of horseradish peroxidase (HRP) and monitoring the reduced PGM signal in response to the target amount...
February 19, 2024: Biosensors & Bioelectronics
https://read.qxmd.com/read/38420553/safety-of-intranasal-insulin-administration-in-patients-undergoing-cardiovascular-surgery-an-open-label-nonrandomized-dose-escalation-study
#20
Yosuke Nakadate, Akiko Kawakami, Takeshi Oguchi, Keisuke Omiya, Hiroyuki Nakajima, Hiroshi Yokomichi, Hiroaki Sato, Thomas Schricker, Takashi Matsukawa
OBJECTIVE: This study aimed to determine the maximum safe dose of intranasal insulin administration during cardiac surgery. METHODS: This open-label, Phase 1, single-center, dose-escalation clinical trial recruited patients scheduled to undergo elective cardiac surgery or major vascular surgery requiring cardiopulmonary bypass between February and September 2021. They were grouped into 5 dose-escalation cohorts and administered 0, 40, 80, 160, and 240 IU insulin (n = 6 in each group) via a metered nasal dispenser after the induction of general anesthesia...
February 2024: JTCVS open
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