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https://www.readbyqxmd.com/read/29761993/-design-and-implementation-of-real-time-continuous-glucose-monitoring-instrument
#1
Yonghong Huang, Hongying Liu, Senfu Tian, Ziru Jia, Zi Wang, Xitian Pi
Real-time continuous glucose monitoring can help diabetics to control blood sugar levels within the normal range. However, in the process of practical monitoring, the output of real-time continuous glucose monitoring system is susceptible to glucose sensor and environment noise, which will influence the measurement accuracy of the system. Aiming at this problem, a dual-calibration algorithm for the moving-window double-layer filtering algorithm combined with real-time self-compensation calibration algorithm is proposed in this paper, which can realize the signal drift compensation for current data...
December 1, 2017: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
https://www.readbyqxmd.com/read/29761957/-the-research-of-near-infrared-blood-glucose-measurement-using-particle-swarm-optimization-and-artificial-neural-network
#2
Juan Dai, Zhong Ji, Yubao Du
Existing near-infrared non-invasive blood glucose detection modelings mostly detect multi-spectral signals with different wavelength, which is not conducive to the popularization of non-invasive glucose meter at home and does not consider the physiological glucose dynamics of individuals. In order to solve these problems, this study presented a non-invasive blood glucose detection model combining particle swarm optimization (PSO) and artificial neural network (ANN) by using the 1 550 nm near-infrared absorbance as the independent variable and the concentration of blood glucose as the dependent variable, named as PSO-2ANN...
August 1, 2017: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
https://www.readbyqxmd.com/read/29757683/electrochemical-enzyme-biosensors-revisited-old-solutions-for-new-problems
#3
Tiago Monteiro, Maria Gabriela Almeida
Worldwide legislation is driving the development of novel and highly efficient analytical tools for assessing the composition of every material that interacts with Consumers or Nature. The biosensor technology is one of the most active R&D domains of Analytical Sciences focused on the challenge of taking analytical chemistry to the field. Electrochemical biosensors based on redox enzymes, in particular, are highly appealing due to their usual quick response, high selectivity and sensitivity, low cost and portable dimensions...
May 14, 2018: Critical Reviews in Analytical Chemistry
https://www.readbyqxmd.com/read/29737214/the-real-world-of-blood-glucose-point-of-care-testing-poct-system-running-in-china-teaching-hospital
#4
Feng-Fei Li, Yun Xie, Bing-Yin Shi, Min Niu, Hui Guo, Yan Cao, Bing-Li Liu, Reng-Na Yan, Xiao-Fei Su, Jin-Dan Wu, Dan-Feng Zhang, Li-Ming Chen, Jian-Hua Ma
BACKGROUND:  The blood glucose point-of-care testing (POCT) system is important in the decision-making process involving patients suspected of having hypoglycemia. To investigate the real world of the POCT system being used in teaching hospitals in China. METHODS: The survey was conducted by Hisend Research Group from May 2015 to July 2015 in four teaching hospitals in China. The survey questions were referred to the ISO 15197:2013 standard requirements for the use of the POCT system in a hospital setting...
May 9, 2018: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/29726429/development-of-a-protocol-for-automated-glucose-measurement-transmission-used-in-clinical-decision-support-systems-based-on-the-continua-design-guidelines
#5
Markus Meyer, Klaus Donsa, Thomas Truskaller, Matthias Frohner, Birgit Pohn, Alexander Felfernig, Frank Sinner, Thomas Pieber
BACKGROUND: A fast and accurate data transmission from glucose meter to clinical decision support systems (CDSSs) is crucial for the management of type 2 diabetes mellitus since almost all therapeutic interventions are derived from glucose measurements. OBJECTIVES: Aim was to develop a prototype of an automated glucose measurement transmission protocol based on the Continua Design Guidelines and to embed the protocol into a CDSS used by healthcare professionals...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29708637/consistency-of-cybernetic-variables-with-gene-expression-profiles-a-more-rigorous-test
#6
Frank DeVilbiss, Aravinda Mandli, Doraiswami Ramkrishna
Diauxic growth of E. coli is driven by a host of internal, complex regulatory actions. In this classic scenario of cellular control, the cell employs a rational algorithm to modulate its metabolism in a competitive fashion. Cybernetic models of metabolism, whose development now spans three decades, were first formulated to describe regulation of cells in complex, multi-substrate environments. They modeled this scenario using the hypothesis that the formation of the enzymatic machinery is regulated to maximize a return on investment...
April 30, 2018: Biotechnology Progress
https://www.readbyqxmd.com/read/29664784/assessing-glucose-meter-accuracy-the-details-matter
#7
Yafen Liang, Mark J Rice
No abstract text is available yet for this article.
May 2018: Anesthesiology
https://www.readbyqxmd.com/read/29624072/enhanced-patient-satisfaction-with-cellular-enabled-glucose-meters-in-pregnancy
#8
Alyson R Pierick, Sarah A Wernimont, Emily A Boevers, Avery M Whitis, Benjamin E Deonovic, Diedre K Fleener, Craig H Syrop, Janet I Andrews
No abstract text is available yet for this article.
April 1, 2018: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29607521/non-invasive-wearable-sensor-for-indirect-glucometry
#9
Gleb Zilberstein, Roman Zilberstein, Uriel Maor, Pier Giorgio Righetti
A non-invasive mini-sensor for blood glucose concentration assessment has been developed. The monitoring is performed by gently pressing a wrist or fingertip onto the chemochromic mixture coating a thin glass or polymer film positioned on the back panel of a smart watch with PPG/HRM (photoplethysmographic/heart rate monitoring sensor). The various chemochromic components measure the absolute values of the following metabolites present in the sweat: acetone, acetone beta-hydroxybutirate, aceto acetate, water, carbon dioxide, lactate anion, pyruvic acid, Na and K salts...
April 2, 2018: Electrophoresis
https://www.readbyqxmd.com/read/29603806/glucose-concentrations-after-insulin-induced-hypoglycemia-and-glycemic-variability-in-healthy-and-diabetic-cats
#10
Eric Zini, Elena Salesov, Perrine Dupont, Laura Moretto, Barbara Contiero, Thomas A Lutz, Claudia E Reusch
BACKGROUND: Little information is available about posthypoglycemic hyperglycemia (PHH) in diabetic cats, and a causal link between hypoglycemia and subsequent hyperglycemia is not clear. Fluctuations in blood glucose concentrations might only represent high glycemic variability. HYPOTHESIS: Insulin induces PHH in healthy cats, and PHH is associated with poorly regulated diabetes and increased glycemic variability in diabetic cats. ANIMALS: Six healthy cats, 133 diabetic cats...
March 30, 2018: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29594599/detection-of-glutathione-based-on-mno-2-nanosheet-gated-mesoporous-silica-nanoparticles-and-target-induced-release-of-glucose-measured-with-a-portable-glucose-meter
#11
Qingqing Tan, Ruirui Zhang, Rongmei Kong, Weisu Kong, Wenzhi Zhao, Fengli Qu
The authors describe a novel method for the determination of glutathione (GSH). Detection is based on target induced release of glucose from MnO2 nanosheet-gated aminated mesoporous silica nanoparticles (MSNs). In detail, glucose is loaded into the pores of MSNs. Negatively charged MnO2 nanosheets are assembled on the MSNs through electrostatic interactions. The nanosheets are reduced by GSH, and this results in the release of glucose which is quantified by using a commercial electrochemical glucose meter. GSH can be quantified by this method in the 100 nM to 10 μM concentration range, with a 34 nM limit of detection...
December 8, 2017: Mikrochimica Acta
https://www.readbyqxmd.com/read/29587254/evaluation-of-the-freestyle%C3%A2-libre-flash-glucose-monitoring-system-in-children-and-adolescents-with-type-1-diabetes
#12
Guy G Massa, Inge Gys, Anniek Op 't Eyndt, Esmiralda Bevilacqua, Anne Wijnands, Peter Declercq, Renate Zeevaert
BACKGROUND/AIMS: The FreeStyle® Libre Flash Glucose Monitoring System (FGM, Abbott) measures glucose concentrations in the interstitial fluid for up to 14 days. It has been approved for use in children aged > 4 years in January 2016. Experience in children is still limited. We evaluated the accuracy and usability of the FGM in children with type 1 diabetes mellitus (DM). METHODS: 67 children with type 1 DM (35 girls), aged 4-18 years, were included. Subjects wore a sensor on the back of their upper arm...
2018: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/29587193/development-of-cu-nanoflowers-modified-the-flexible-needle-type-microelectrode-and-its-application-in-continuous-monitoring-glucose-in-vivo
#13
Yuxin Fang, Shenjun Wang, Yangyang Liu, Zhifang Xu, Kuo Zhang, Yi Guo
A minimally invasive glucose microbiosensor based the flexibly integrated electrode for continuous monitoring glucose in vivo has been developed in this study. This was achieved by coating needle-type microelectrode with Cu nanoflowers, nafion, glucose oxidase (GOD) and polyurethane (PU) membranes, successfully prepared with layer-by-layer deposition. The Cu nanomaterials provided a large specific surface area and electrocatalytic activity for glucose detection. The PU layers as mass-transport limiting membranes significantly enhanced the linearity and stability of sensors...
March 13, 2018: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29575134/glucose-alert-system-improves-health-professional-responses-to-adverse-glycaemia-and-reduces-the-number-of-hyperglycaemic-episodes-in-non-critical-care-inpatients
#14
M Kyi, P R Wraight, L M Rowan, K A Marley, P G Colman, S Fourlanos
AIM: To investigate the effect of a novel glucose alert system, comprising the Melbourne Glucose Alert Pathway and glucose-alert-capable networked blood glucose meters, on nursing and hospital medical officer responses to adverse glycaemia. METHODS: A prospective, pre- and post-observational study was undertaken in non-critical care wards of a tertiary hospital over 4 months (n=148 or 660 patient-days). The intervention consisted of two components designed to promote a consistent staff response to blood glucose measurements: (1) a clinical escalation pathway, the Melbourne Glucose Alert Pathway, and (2) networked blood glucose meters, which provide a visual alert for out-of-range blood glucose measurement...
March 25, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29560632/-effect-of-different-stimulating-strength-of-electroacupuncture-on-gastrointestinal-motility-and-rhoa-rock-signaling-in-gastric-antral-smooth-muscle-in-diabetic-gastroparesis-rats
#15
Xue-Fen Wu, Xiao-Li Chen, Xue-Na Zheng, Xin Guo, Zhi-Qiang Xie, Li Liu, Xin-Ran Wei, Zeng-Hui Yue
OBJECTIVE: To observe the effect of different strength of electroacupuncture (EA) stimulation on gastrointestinal motility and Ras homolog gene family member (RhoA)/Rho associated coiled-coil forming protein kinase (ROCK) signaling in diabetic gastroparesis (DGP) rats, so as to reveal the underlying mechanisms of EA for improving DGP. METHODS: Sixty SD rats were randomly and equally divided into blank control, DGP model, weak EA, medium EA, and strong EA groups ( n =12 rats in each)...
March 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29556158/calorie-restriction-regime-enhances-physical-performance-of-trained-athletes
#16
Victoria Pons, Joan Riera, Xavier Capó, Miquel Martorell, Antoni Sureda, Josep A Tur, Franchek Drobnic, Antoni Pons
Background: Caloric restriction induces mitochondrial biogenesis and improves physical fitness in rodents. We aimed to provide evidence of how caloric restriction affects the body composition and physical performance of trained athletes and to evaluate the possible impact of an every-other-day feeding diet on nutritional deficiencies of micronutrients and essential fatty acids. Methods: The study was performed with 12 healthy male athletes by carrying out a 33% caloric restriction with respect to their usual diet...
2018: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/29555653/treadmill-exercise-alleviates-diabetic-cardiomyopathy-by-suppressing-plasminogen-activator-inhibitor-expression-and-enhancing-enos-in-streptozotocin-induced-male-diabetic-rats
#17
Wang Chengji, Fan Xianjin
OBJECTIVE: To investigate the biological mechanism of the effect of different intensity exercises on diabetic cardiomyopathy. METHODS: 87 male SPF 6-wks old male S-D rats, after 6 weeks high fat diet, diabetic model was established, randomly selected 43 divided into diabetic control group (DCG, n=10), low intensity group (LIG, n=11), moderate intensity group (MIG, n=11), and high-intensity group (HIG, n=11).The rats in LIG were forced to run on a motorized treadmill, the exercise load consisted of running at a speed of 10 meters/min, MIG were running 15 meters/min, HIG were running 20 meters/min, one hour a day for 6 weeks...
March 19, 2018: Endocrine Connections
https://www.readbyqxmd.com/read/29541282/continuous-monitoring-of-glucose-for-type-1-diabetes-a-health-technology-assessment
#18
(no author information available yet)
Background: Type 1 diabetes is a condition in which the pancreas produces little or no insulin. People with type 1 diabetes must manage their blood glucose levels by monitoring the amount of glucose in their blood and administering appropriate amounts of insulin via injection or an insulin pump. Continuous glucose monitoring may be beneficial compared to self-monitoring of blood glucose using a blood glucose meter. It provides insight into a person's blood glucose levels on a continuous basis, and can identify whether blood glucose levels are trending up or down...
2018: Ontario Health Technology Assessment Series
https://www.readbyqxmd.com/read/29504207/advancing-diabetes-management-in-adolescents-comparative-effectiveness-of-mobile-self-monitoring-blood-glucose-technology-and-family-centered-goal-setting
#19
Tamara S Hannon, Lisa G Yazel-Smith, Amy S Hatton, Jennifer L Stanton, Elizabeth A S Moser, Xiaochun Li, Aaron E Carroll
BACKGROUND: As adolescents gain autonomy, it remains important for parents to be involved with diabetes management to avoid deterioration in glycemic control. Technologies for self-monitoring of blood glucose (SMBG) allow for remote monitoring in real-time by parents. This research compared 3 strategies for improving SMBG and diabetes self-care in the short-term. These strategies were: (1) health information technology (HIT)-enhanced blood glucose meter that shared blood glucose data among patients, their parent, and care providers, and allowed for text messaging; (2) family-centered goal setting; and (3) a combination of (1) and (2)...
June 2018: Pediatric Diabetes
https://www.readbyqxmd.com/read/29498303/design-of-non-invasive-glucose-meter-using-near-infrared-technique
#20
Gameel Saleh, Fatimah Alkaabi, Noor Al-Hajhouj, Fatimah Al-Towailib, Safa Al-Hamza
Diabetics need to keep track of their blood glucose level and measure it regularly to determine their insulin dose intake and to ensure that glucose level is always within the normal range. In this article, a system that enables the measurement of blood glucose level non-invasively is designed. This article uses a near infra-red (NIR) transmittance spectroscopy, without drawing blood, puncturing the skin, or causing pain. It involves a light source and light detector circuits positioned on a certain region of the body...
February 2018: Journal of Medical Engineering & Technology
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