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https://www.readbyqxmd.com/read/28513731/ag-au-nanoprism-metal-organic-framework-based-paper-for-extending-the-glucose-sensing-range-in-human-serum-and-urine
#1
Pin-Hsuan Huang, Chia Ping Hong, Jian Fan Zhu, Tzu-Ting Chen, Chu-Ting Chan, Yu-Chien Ko, Tien-Li Lin, Zheng-Bang Pan, Ning-Kuei Sun, Ying-Chu Wang, Jong-Jheng Luo, Tzu-Chieh Lin, Chia-Cheng Kang, Jing-Jong Shyue, Mei-Lin Ho
In this work, we present a Ag@Au nanoprism-metal-organic framework-paper based glucose sensor for rapid, sensitive, single-use and quantitative glucose determination in human serum. To achieve painless measurement of glucose with a non-invasive detection methodology, this biosensor was further tested in human urine. In this approach, a new hybrid-Ag@Au nanoprism loaded in close proximity to micrometer sized coordination polymers as phosphorescent luminophores significantly enhanced the emission intensity due to metal-enhanced phosphorescence and worked as reaction sites to support more dissolved oxygen...
May 17, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28501411/short-communication-associations-between-blood-glucose-concentration-onset-of-hyperketonemia-and-milk-production-in-early-lactation-dairy-cows
#2
J Ruoff, S Borchardt, W Heuwieser
The objectives of this study were to describe the associations between hypoglycemia and the onset of hyperketonemia (HYK) within the first 6 wk of lactation, to evaluate the effects of body condition score at calving on glucose concentration, and to study the effects of hypoglycemia on milk production. A total of 621 dairy cows from 6 commercial dairy farms in Germany were enrolled between 1 and 4 d in milk (DIM). Cows were tested twice weekly using an electronic handheld meter for glucose and β-hydroxybutyrate (BHB), respectively, for a period of 42 d...
May 10, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28495347/a-web-based-clinical-decision-support-system-for-gestational-diabetes-automatic-diet-prescription-and-detection-of-insulin-needs
#3
Estefanía Caballero-Ruiz, Gema García-Sáez, Mercedes Rigla, María Villaplana, Belen Pons, M Elena Hernando
BACKGROUND: The growth of diabetes prevalence is causing an increasing demand in health care services which affects the clinicians' workload as medical resources do not grow at the same rate as the diabetic population. Decision support tools can help clinicians with the inspection of monitoring data, providing a preliminary analysis to ease their interpretation and reduce the evaluation time per patient. This paper presents Sinedie, a clinical decision support system designed to manage the treatment of patients with gestational diabetes...
June 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28459160/introduction-of-a-novel-smartphone-coupled-blood-glucose-monitoring-system
#4
Nina Jendrike, Annette Baumstark, Chieh-Hsiao Chen, Delia Rittmeyer, Cornelia Haug, Guido Freckmann
The novel system for self-monitoring of blood glucose (SMBG) PixoTest couples SMBG to a smartphone and does not require a separate glucose meter. The integrated system includes all components necessary for a glucose measurement, and owing to a colorimetric measurement principle, a smartphone camera can capture color changes and a software app calculates the corresponding glucose value. In the presented study, the system was evaluated in terms of system accuracy as described in ISO 15197:2013. It was shown to fulfill system accuracy requirements with 97-99% of results from three different reagent system lots within the accuracy limits and 100% of results within zone A of the consensus error grid...
April 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28459033/patient-and-health-care-professional-satisfaction-with-a-new-simple-high-accuracy-blood-glucose-meter-with-color-range-indicator
#5
Laurence B Katz, Mike Grady, Lorna Stewart, Hilary Cameron, Pamela A Anderson, Anish Desai
BACKGROUND: Accurate self-monitoring of blood glucose (BG) is a key component of effective self-management of glycemic control. METHODS: The OneTouch Select Plus Simple™ (OTSPS) BG monitoring system (BGMS) was evaluated for accuracy in a clinical setting. RESULTS: OTSPS was accurate over a wide glucose range and met lay user and system accuracy BG standards described in ISO 15197:2013. Patients also used OTSPS for a 1-week trial period and reported their level of satisfaction with meter features...
March 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28457032/prevalence-of-cardiovascular-risk-factors-among-diabetic-population-and-awareness-of-diabetes-among-diabetic-patients-a-population-based-himalayan-study
#6
Jatinder Mokta, Kiran Mokta, Asha Ranjan, Mehak Garg
BACKGROUND: To determine the prevalence of modifiable cardiovascular risk factors among adults with diabetes in the remote Himalayan areas, at elevation range from 350 meters (1,148ft) to 6900 meters (22,966ft) above sea level, in the Indian state of Himachal Pradesh. MATERIAL AND METHODS: Study was conducted in 21 rural areas of Himachal Pradesh situated at 2200 to 10,000 feet altitude. Non-pregnant diabetic adults (>18years) were surveyed, through 32 diabetic camps...
February 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28451316/quantitative-self-powered-electrochromic-biosensors
#7
Miguel Aller Pellitero, Anton Guimerà, Maria Kitsara, Rosa Villa, Camille Rubio, Boris Lakard, Marie-Laure Doche, Jean-Yves Hihn, F Javier Del Campo
Self-powered sensors are analytical devices able to generate their own energy, either from the sample itself or from their surroundings. The conventional approaches rely heavily on silicon-based electronics, which results in increased complexity and cost, and prevents the broader use of these smart systems. Here we show that electrochromic materials can overcome the existing limitations by simplifying device construction and avoiding the need for silicon-based electronics entirely. Electrochromic displays can be built into compact self-powered electrochemical sensors that give quantitative information readable by the naked eye, simply controlling the current path inside them through a combination of specially arranged materials...
March 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28445812/portable-aptamer-biosensor-of-platelet-derived-growth-factor-bb-using-a-personal-glucose-meter-with-triply-amplified
#8
Lu Hong, Fu Zhou, Dongmin Shi, Xiaojun Zhang, Guangfeng Wang
Sensitive and rapid detection of platelet-derived growth factor BB (PDGF-BB), a cancer-related protein, could help early diagnosis, treatment, and prognosis of cancers. Although some methods have been developed to detect PDGF-BB, few can provide quantitative results using an affordable and portable device that is suitable for home use or field application. In this work, we report the first use of a portable kind of personal glucose meter (PGM) combining a catalytic and molecular beacon (CAMB) system with a cation exchange reaction (CX reaction) for ultrasensitive PDGF-BB assay...
September 15, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28443343/impact-on-diabetes-self-management-and-glycemic-control-of-a-new-color-based-smbg-meter
#9
Oliver Schnell, Gerd Klausmann, Bettina Gutschek, Rosa Maria Garcia-Verdugo, Michael Hummel
BACKGROUND: Self-monitoring of blood glucose (SMBG) is a key pillar of personal diabetes management. The objective of this observational study was to analyze diabetes self-management (DSM) and glycemic outcomes before and during system implementation in real-life settings of a blood glucose meter system with a color-coded display of glucose levels, which helps identify out-of-range levels. METHODS: A total of 193 insulin-treated diabetes patients (11% T1DM; 55% male, age 60 ± 4 years, mean diabetes duration 14 ± 9 years, HbA1c 8...
April 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28429065/rapid-electrochemical-quantification-of-salmonella-pullorum-and-salmonella-gallinarum-based-on-glucose-oxidase-and-antibody-modified-silica-nanoparticles
#10
Yiheng Luo, Wenchao Dou, Guangying Zhao
In this article, a facile and sensitive electrochemical method for quantification of Salmonella Pullorum and Salmonella Gallinarum (S. Pullorum and S. Gallinarum) was established by monitoring glucose consumption with a personal glucose meter (PGM). Antibody-functionalized magnetic nanoparticles (IgG-MNPs) were used to capture and enrich S. Pullorum and S. Gallinarum, and IgG-MNPs-S. Pullorum and IgG-MNPs-S. Gallinarum complexes were magnetically separated from a sample using a permanent magnet. The trace tag was prepared by loading polyclonal antibodies and high-content glucose oxidase on amino-functionalized silica nanoparticles (IgG-SiNPs-GOx)...
April 21, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28417082/improving-glucose-tolerance-by-muscle-damaging-exercise
#11
Chien-Te Ho, Machiko Otaka, Chia-Hua Kuo
Tissue damage is regarded as an unwanted medical condition to be avoided. However, introducing tolerable tissue damages has been used as a therapeutic intervention in traditional and complementary medicine to cure discomfort and illness. Eccentric exercise is known to cause significant necrosis and insulin resistance of skeletal muscle. The purpose of this study was to determine the magnitude of muscle damage and blood glucose responses during an oral glucose tolerance test (OGTT) after eccentric training in 21 young participants...
April 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/28394194/the-higher-the-insulin-resistance-the-lower-the-cardiac-output-in-men-with-type-1-diabetes-during-the-maximal-exercise-test
#12
Pawel Niedzwiecki, Dariusz Naskret, Stanislaw Pilacinski, Maciej Pempera, Aleksandra Uruska, Anna Adamska, Dorota Zozulinska-Ziolkiewicz
BACKGROUND: The aim of this study was to assess the hemodynamic parameters analyzed in bioimpedance cardiography during maximal exercise in patients with type 1 diabetes differing in insulin resistance. METHODS: The study group consisted of 40 men with type 1 diabetes. Tissue sensitivity to insulin was assessed on the basis of the glucose disposal rate (GDR) analyzed during hyperinsulinemic-euglycemic clamp. Patients were divided into groups with GDR <4.5 mg/kg/min (G1 group-lower insulin sensitivity) and GDR ≥4...
June 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/28376646/why-the-diabetes-technology-society-surveillance-protocol-for-glucose-meters-needs-to-be-revised
#13
Jan S Krouwer
The Diabetes Technology Society surveillance protocol provides a seal of approval for a glucose meter if a sufficient number of a candidate glucose meter's results meet ISO 15197:2013 limits. The protocol provides clear details about how to conduct this study and analyze the data but has two flaws. There is no specification about the size of glucose meter errors that are outside of ISO limits. A meter that has a result in the E zone of a glucose meter error grid could receive the DTS seal of approval. In addition, the protocol uses the ISO standard, which could be considered a "state of the art" standard instead of an error grid, which is a clinical standard...
April 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28351626/integrated-immunochromatographic-strip-with-glucometer-readout-for-rapid-quantification-of-phosphorylated-proteins
#14
Yuting Zhao, Xiao Chen, Sophie Lin, Dan Du, Yuehe Lin
A new technology to quantify phospho-p53(15) by converting its content to the amount of glucose which is detectable by a glucometer was developed. An immunochromatographic test strip (ITS) was used as a disposable platform, where primary antibody (Ab1)-modified Fe3O4 magnetic nanoparticles (Fe3O4-Ab1) were settled on the test zone to capture both the target phospho-p53(15) and the detection antibody (Ab2)-glucose encapsulating liposome (GEL) conjugate. The measurement was based on the release and subsequent detection of glucose from Ab2-GEL using a glucose meter (GM)...
April 29, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28346671/in-this-issue-april-2017-first-employment-data-from-a-rural-vet-school-%C3%A2-%C3%A2-%C3%A2-risk-factors-for-neospora-in-beef-herds-%C3%A2-%C3%A2-%C3%A2-luteal-structures-increase-pregnancy-odds-after-ovsynch%C3%A2-%C3%A2-%C3%A2-%C3%A2-anterior-nasal-atresia-in-half-sibling-calves-%C3%A2-%C3%A2-%C3%A2-hand-held-glucose-meter
#15
EDITORIAL
https://www.readbyqxmd.com/read/28346669/evaluation-of-a-point-of-care-electrochemical-meter-to-detect-subclinical-ketosis-and-hypoglycaemia-in-lactating-dairy-cows
#16
A Zakian, M Tehrani-Sharif, M R Mokhber-Dezfouli, M Nouri, P D Constable
OBJECTIVES: To evaluate and validate a hand-held electrochemical meter (Precision Xtra®) as a screening test for subclinical ketosis and hypoglycaemia in lactating dairy cattle. DESIGN: Method comparison study using a convenience sample. PROCEDURE: Blood samples were collected into plain tubes from the coccygeal vessels of 181 Holstein cows at 2-4 weeks of lactation during summer in Iran. Blood β-hydroxybutyrate concentration (BHB) and glucose concentration were immediately measured by the electrochemical meter after applying 20 μL of blood to the reagent strip...
April 2017: Australian Veterinary Journal
https://www.readbyqxmd.com/read/28333238/clustering-of-pcos-like-traits-in-naturally-hyperandrogenic-female-rhesus-monkeys
#17
D H Abbott, B H Rayome, D A Dumesic, K C Lewis, A K Edwards, K Wallen, M E Wilson, S E Appt, J E Levine
STUDY QUESTION: Do naturally occurring, hyperandrogenic (≥1 SD of population mean testosterone, T) female rhesus monkeys exhibit traits typical of women with polycystic ovary syndrome (PCOS)? SUMMARY ANSWER: Hyperandrogenic female monkeys exhibited significantly increased serum levels of androstenedione (A4), 17-hydroxyprogesterone (17-OHP), estradiol (E2), LH, antimullerian hormone (AMH), cortisol, 11-deoxycortisol and corticosterone, as well as increased uterine endometrial thickness and evidence of reduced fertility, all traits associated with PCOS...
April 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28332406/continuous-glucose-monitor-interference-with-commonly-prescribed-medications
#18
Ananda Basu, Michael Q Slama, Wayne T Nicholson, Loralie Langman, Thomas Peyser, Rickey Carter, Rita Basu
BACKGROUND: Reliability of continuous glucose monitors (CGM) is a prerequisite for therapeutic dosing of insulin without the need for confirmatory blood glucose meter measurements. Interference of CGMs with commonly prescribed substances has not been extensively evaluated. METHODS: We sought to undertake a novel pilot study to determine the susceptibility of FDA-approved CGM systems (Medtronic Guardian Sof-Sensor, Dexcom G4 Platinum) to erroneous readings in the presence of common medications...
March 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28328679/results-of-a-multicenter-prospective-pivotal-trial-of-the-first-inline-continuous-glucose-monitor-in-critically-ill-patients
#19
Grant V Bochicchio, Stan Nasraway, Laura Moore, Anthony Furnary, Eden Nohra, Kelly Bochicchio
BACKGROUND: We have previously demonstrated that tight glycemic control (80-120 mg/dL) improves outcome in critically injured patients. However, many centers have gotten away from aggressive glucose control due to the workload and risk of hypoglycemia. The objective of this pivotal trial is to evaluate the first in human continuous inline glucose monitor (OptiScanner) in critically ill patients. METHODS: A multicenter pivotal trial was conducted over a 1-year period (2014-2015) at four major academic centers in 200 critically ill patients...
June 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28326795/digital-health-care-by-in-silico-glycation-of-hba1-blood-cells
#20
James M Minor, Leslie M Rickey, Richard M Bergenstal
BACKGROUND: Diabetes health care relies on the HbA1c (A1c) assay and associated average glucose (AG) to evaluate and control chronic glycemia. However, the A1c assay is plagued with significant noise, lag time, and specificity issues. Current studies support the significant health care advantage of clinical action based on real-time blood glucose (BG) metrics. We seek to improve diabetes management by directly relating such metrics to AG levels as mediated by recently discovered recurrent endocrine cycles...
March 1, 2017: Journal of Diabetes Science and Technology
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