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bovine colostrum

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https://www.readbyqxmd.com/read/28702050/circulating-micrornas-in-serum-from-cattle-challenged-with-bovine-viral-diarrhea-virus
#1
Tasia M Taxis, Fernando V Bauermann, Julia F Ridpath, Eduardo Casas
Bovine viral diarrhea virus (BVDV) is an RNA virus that is often associated with respiratory disease in cattle. MicroRNAs have been proposed as indicators of exposure to respiratory pathogens. The objective of this study was to identify microRNAs in cattle that had been challenged with a non-cytopathic field strain of BVDV. Five colostrum deprived neonate Holstein calves were inoculated with BVDV (challenged) and 4 were mock challenged (control). Serum from all calves was collected at four different times: prior to challenge (day 0) and at 4, 9, and 16 days post-challenge...
2017: Frontiers in Genetics
https://www.readbyqxmd.com/read/28691242/bovine-colostrum-enriched-with-lyophilized-bovine-colostrum-stimulates-intestinal-epithelium-renewal-of-holstein-calves-in-the-first-days-of-life
#2
L Kindlein, D B Moretti, P Pauletti, A R Bagaldo, A P O Rodrigues, R Machado-Neto
Consumption of a second meal of colostrum with high quality could contribute to the intestinal epithelium development, especially if there is poor supply of colostrum just after birth. The effect of a second colostrum meal was evaluated on histomorphometry of the intestinal mucosa of newborn Holstein calves fed with high- and low-quality first colostrum. Seventy-two calves were fed with a first colostrum meal with high (HFM, close to 100 mg/ml) or low (LFM, close to 30 mg/ml) IgG concentration. At 12 hr of life, three treatments of second colostrum feeding were applied to the calves either fed high or low first colostrum: calves fed with low (LOW-close to 30 mg/ml) or high (HIGH-close to 100 mg/ml) IgG concentration; and colostrum enriched with lyophilized bovine colostrum with high IgG concentration (ENRICHED-higher than 120 mg/ml), resulting in six groups...
July 10, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28678850/herd-level-animal-management-factors-associated-with-the-occurrence-of-bovine-neonatal-pancytopenia-in-calves-in-a-multi-country-study
#3
Carola Sauter-Louis, Bryony A Jones, Jörg Henning, Alexander Stoll, Mirjam Nielen, Gerdien Van Schaik, Anja Smolenaars, Matthijs Schouten, Ingrid den Uijl, Christine Fourichon, Raphael Guatteo, Aurélien Madouasse, Simon Nusinovici, Piet Deprez, Sarne De Vliegher, Jozef Laureyns, Richard Booth, Jacqueline M Cardwell, Dirk U Pfeiffer
Since 2007, mortality associated with a previously unreported haemorrhagic disease has been observed in young calves in several European countries. The syndrome, which has been named 'bovine neonatal pancytopenia' (BNP), is characterised by thrombocytopenia, leukocytopenia and a panmyelophthisis. A herd-level case-control study was conducted in four BNP affected countries (Belgium, France, Germany and the Netherlands) to identify herd management risk factors for BNP occurrence. Data were collected using structured face-to-face and telephone interviews of farm managers and their local veterinarians...
2017: PloS One
https://www.readbyqxmd.com/read/28658720/enteral-lactoferrin-supplementation-for-prevention-of-sepsis-and-necrotizing-enterocolitis-in-preterm-infants
#4
REVIEW
Mohan Pammi, Gautham Suresh
BACKGROUND: Lactoferrin, a normal component of human colostrum and milk, can enhance host defenses and may be effective for prevention of sepsis and necrotizing enterocolitis (NEC) in preterm neonates. OBJECTIVES: Primary objective 1. To assess the safety and effectiveness of lactoferrin supplementation to enteral feeds for prevention of sepsis and NEC in preterm neonates Secondary objectives 1. To determine the effects of lactoferrin supplementation to enteral feeds to prevent neonatal sepsis and/or NEC on duration of positive-pressure ventilation, development of chronic lung disease (CLD) or periventricular leukomalacia (PVL), length of hospital stay to discharge among survivors, and adverse neurological outcomes at two years of age or later2...
June 28, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28653977/exploitation-of-spr-to-investigate-the-importance-of-glycan-chains-in-the-interaction-between-lactoferrin-and-bacteria
#5
Noelle O'Riordan, Michelle Kilcoyne, Lokesh Joshi, Rita M Hickey
Bovine lactoferrin (LF) has been shown to prevent adhesion to and invasion of mammalian cell lines by pathogenic bacteria, with evidence for direct bacterial binding by the milk glycoprotein. However, the glycosylation pattern of LF changes over the lactation cycle. In this study, we aim to investigate the effect that this variation has on the milk glycoprotein's ability to interact with pathogens. Surface plasmon resonance technology was employed to compare the binding of LF from colostrum (early lactation) and mature milk (late lactation) to a panel of pathogenic bacteria (Staphylococcus aureus, Escherichia coli, Cronobacter sakazakii, Streptococcus pneumoniae, Pseudomonas aeruginosa, Listeria monocytogenes and Salmonella typhimurium)...
June 27, 2017: Sensors
https://www.readbyqxmd.com/read/28653384/in-this-issue-july-2017-rhdv-vaccine-protects-against-both-strains-of-virus-%C3%A2-%C3%A2-%C3%A2-olfactory-neuroblastoma-in-a-malamute-%C3%A2-%C3%A2-%C3%A2-coincidental-conditions-affecting-dysphagia-in-a-miniature-poodle-%C3%A2-%C3%A2-%C3%A2-support-for-storing-high-quality-bovine-colostrum-%C3%A2-%C3%A2-%C3%A2-sarcoptic
#6
EDITORIAL
https://www.readbyqxmd.com/read/28652648/role-of-ph-in-the-recovery-of-bovine-milk-oligosaccharides-from-colostrum-whey-permeate-by-nanofiltration
#7
Joshua L Cohen, Daniela Barile, Yan Liu, Juliana M L N de Moura Bell
Milk oligosaccharides are associated with improved health outcomes in infants. Nanofiltration (NF) is used for isolation of bovine milk oligosaccharides (BMO). The study aim was to improve the recovery of BMO from lactose-hydrolyzed colostrum whey permeate. The retention factors of carbohydrates at various pH and transmembrane pressures were determined for a nanofiltration membrane, which was used at pilot scale to purify BMO. Carbohydrates were quantified by liquid chromatography and characterized using nano-LC-Chip-QToF mass spectrometry...
March 2017: International Dairy Journal
https://www.readbyqxmd.com/read/28637804/bioactive-immune-components-of-anti-diarrheagenic-enterotoxigenic-e-coli-etec-hyperimmune-bovine-colostrum-products
#8
Khandra T Sears, Sharon M Tennant, Mardi K Reymann, Raphael Simon, Nicky Konstantopoulos, William C Blackwelder, Eileen M Barry, Marcela F Pasetti
Diarrhea is a common illness among travelers to resource-limited countries, the most prevalent attributable agent being enterotoxigenic Escherichia coli (ETEC). There are presently no vaccines licensed specifically for the prevention of ETEC-induced traveler's diarrhea (TD), and this has propelled investigation of alternative preventive methods. Colostrum, the first milk expressed after birthing, is rich in immunoglobulins and innate immune components for protection of newborns against infectious agents. Hyperimmune bovine colostrum (HBC) produced by immunization of cows during gestation (and containing high levels of specific antibodies) is a practical and effective prophylactic tool against gastrointestinal illnesses...
June 21, 2017: Clinical and Vaccine Immunology: CVI
https://www.readbyqxmd.com/read/28623367/bovine-antibodies-targeting-primary-and-recurrent-clostridium-difficile-disease-are-a-potent-antibiotic-alternative
#9
Melanie L Hutton, Bliss A Cunningham, Kate E Mackin, Shelley A Lyon, Meagan L James, Julian I Rood, Dena Lyras
The increased incidence of antibiotic resistant 'superbugs' has amplified the use of broad spectrum antibiotics worldwide. An unintended consequence of antimicrobial treatment is disruption of the gastrointestinal microbiota, resulting in susceptibility to opportunistic pathogens, such as Clostridium difficile. Paradoxically, treatment of C. difficile infections (CDI) also involves antibiotic use, leaving patients susceptible to re-infection. This serious health threat has led to an urgent call for the development of new therapeutics to reduce or replace the use of antibiotics to treat bacterial infections...
June 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28596790/high-doses-of-halotolerant-gut-indigenous-lactobacillus-plantarum-reduce-cultivable-lactobacilli-in-newborn-calves-without-increasing-its-species-abundance
#10
Alexander Rodriguez-Palacios, Henry R Staempfli, J Scott Weese
To elucidate the ecological effect of high oral doses of halotolerant (resistant to table salt) indigenous-gut bacteria on other commensals early in life, we conducted a culture-based study to quantify the effect of intestinal Lactobacillus plantarum strain of bovine origin (with remarkable aerobic growth capabilities and inhibitory activity against Escherichia coli O157:H7 and F5) on clinical health and gut lactobacilli/coliforms in newborn calves. In a double-blind placebo-randomized trial twelve colostrum-fed calves, consecutively born at a farm, were fed L...
2017: International Journal of Microbiology
https://www.readbyqxmd.com/read/28566122/necrotizing-enterocolitis-classification-and-two-initial-steps-towards-prevention
#11
Sandra Meinich Juhl
The premature infant suffers from immaturity of all organ systems, one of them being the gastrointestinal tract. When the infant is born, the immature gastrointestinal tract is exposed to milk and simultaneously colonized by high densities of bacteria. The combination of milk, microbiota and an immature gut, leaves the infant vulnerable to developing the dreaded intestinal emergency necrotizing enterocolitis (NEC). NEC is often very aggressive and no cure exists, which means that prevention is an utmost important topic to researchers, physicians, parents - and infants...
June 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/28494925/comparison-of-humoral-and-t-cell-mediated-immune-responses-to-a-single-dose-of-bovela-%C3%A2-live-double-deleted-bvdv-vaccine-or-to-a-field-bvdv-strain
#12
Ratree Platt, Lyle Kesl, Christian Guidarini, Chong Wang, James A Roth
The objective of this study was to determine and compare the humoral and cellular immune responses of calves exposed to a single dose of Bovela(®) bovine viral diarrhea virus (BVDV) live double deleted vaccine or a field strain virus (FSV) of BVDV type 2 (strain 890). Thirty seronegative, colostrum-deprived 5 month-old Holstein steer calves that tested negative for persistent BVDV by ear notch immunohistochemistry and seronegative to BVDV types 1 and 2 were used. Calves were screened by multi-parameter flow cytometry (MP-FCM) 1 week before vaccination to ensure that they were negative for T cell responses to the BVDV types 1 and 2 viruses in the Bovela(®) vaccine...
May 2017: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/28460652/the-microbial-community-of-the-gut-differs-between-piglets-fed-sow-milk-milk-replacer-or-bovine-colostrum
#13
Ann-Sofie R Poulsen, Nadieh de Jonge, Sugiharto Sugiharto, Jeppe L Nielsen, Charlotte Lauridsen, Nuria Canibe
The aim of this study was to characterise the gut microbiota composition of piglets fed bovine colostrum (BC), milk replacer (MR) or sow milk (SM) in the post-weaning period. Piglets (n 36), 23-d old, were randomly allocated to the three diets. Faecal samples were collected at 23, 25, 27 and 30 d of age. Digesta from the stomach, ileum, caecum and mid-colon was collected at 30 d of age. Bacterial DNA from all samples was subjected to amplicon sequencing of the 16S rRNA gene. Bacterial enumerations by culture and SCFA analysis were conducted as well...
May 2, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28414597/bovine-colostral-cells-the-often-forgotten-component-of-colostrum
#14
Diego D Gonzalez, Maria J Dus Santos
No abstract text is available yet for this article.
May 1, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28397754/oral-supplementation-with-bovine-colostrum-decreases-intestinal-permeability-and-stool-concentrations-of-zonulin-in-athletes
#15
Maciej Hałasa, Dominika Maciejewska, Magdalena Baśkiewicz-Hałasa, Bogusław Machaliński, Krzysztof Safranow, Ewa Stachowska
Increased intestinal permeability has been implicated in various pathologies, has various causes, and can develop during vigorous athletic training. Colostrum bovinum is a natural supplement with a wide range of supposed positive health effects, including reduction of intestine permeability. We assessed influence of colostrum supplementation on intestinal permeability related parameters in a group of 16 athletes during peak training for competition. This double-blind placebo-controlled study compared supplementation for 20 days with 500 mg of colostrum bovinum or placebo (whey)...
April 8, 2017: Nutrients
https://www.readbyqxmd.com/read/28335407/bovine-colostrum-whey-protein-hydrolysate-inhibits-cell-dna-damage-and-ldl-oxidation-in-vitro
#16
Shu-Hua Chiang, Shiu-Yu Wang, Chi-Yue Chang, Chih-Wei Chen
Whey protein isolated from bovine colostrums collected on the second day postpartum was two-stage hydrolyzed by alcalase and flavourzyme [...].
March 13, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28316968/a-stepwise-pilot-study-of-bovine-colostrum-to-supplement-the-first-enteral-feeding-in-preterm-infants-precolos-study-protocol-and-initial-results
#17
Yanqi Li, Sandra M Juhl, Xuqiang Ye, René L Shen, Elisabeth Omolabake Iyore, Yiheng Dai, Per T Sangild, Gorm O Greisen
STUDY PROTOCOL: The optimal feeding for preterm infants during the first weeks is still debated, especially when mother's own milk is lacking or limited. Intact bovine colostrum (BC) contains high amounts of protein, growth factors, and immuno-regulatory components that may benefit protein intake and gut maturation. We designed a pilot study to investigate the feasibility and tolerability of BC as the first nutrition for preterm infants. The study was designed into three phases (A, B, and C) and recruited infants with birth weights of 1,000-1,800 g (China) or gestational ages (GAs) of 27 + 0 to 32 + 6 weeks (Denmark)...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28290293/comparative-proteomic-analysis-of-milk-derived-exosomes-in-human-and-bovine-colostrum-and-mature-milk-samples-by-itraq-coupled-lc-ms-ms
#18
Mei Yang, Dahe Song, Xueyan Cao, Rina Wu, Biao Liu, Wenhui Ye, Junrui Wu, Xiqing Yue
Exosomes are membranous vesicles found in biological fluids with important functions. However, milk-derived exosome proteins from humans and bovines have not been studied in detail. The advanced iTRAQ proteomic approach was used to analyze milk-derived exosomes in human and bovine colostrum and mature milk samples. A total of 920 milk exosome proteins were identified and quantified. Among these, 575 differentially expressed exosome proteins (P<0.05) were found. Multivariate analysis, gene ontology (GO) annotation and the KEGG pathway were used to interpret the identified proteins...
February 2017: Food Research International
https://www.readbyqxmd.com/read/28290057/intestinal-fatty-acid-binding-protein-and-gut-permeability-responses-to-exercise
#19
RANDOMIZED CONTROLLED TRIAL
Daniel S March, Tania Marchbank, Raymond J Playford, Arwel W Jones, Rhys Thatcher, Glen Davison
PURPOSE: Intestinal cell damage due to physiological stressors (e.g. heat, oxidative, hypoperfusion/ischaemic) may contribute to increased intestinal permeability. The aim of this study was to assess changes in plasma intestinal fatty acid-binding protein (I-FABP) in response to exercise (with bovine colostrum supplementation, Col, positive control) and compare this to intestinal barrier integrity/permeability (5 h urinary lactulose/rhamnose ratio, L/R). METHODS: In a double-blind, placebo-controlled, crossover design, 18 males completed two experimental arms (14 days of 20 g/day supplementation with Col or placebo, Plac)...
May 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28285432/a-low-dose-6-week-bovine-colostrum-supplementation-maintains-performance-and-attenuates-inflammatory-indices-following-a-loughborough-intermittent-shuttle-test-in-soccer-players
#20
Yiannis Kotsis, Anastasia Mikellidi, Cleopatra Aresti, Eleni Persia, Aristomenis Sotiropoulos, Demosthenes B Panagiotakos, Smaragdi Antonopoulou, Tzortzis Nomikos
PURPOSE: The aim of the study was to investigate the effect of a 6-week, low-dose bovine colostrum (BC) supplementation on exercise-induced muscle damage (EIMD) and performance decline in soccer players following the Loughborough Intermittent Shuttle Test (LIST) during a competitive season period. METHODS: In a double-blind, randomized, placebo-controlled design, two groups of soccer players were allocated to a 3.2 g/day of whey protein (WP, N = 8) or BC (N = 10) and performed a pre- and a post-supplementation LIST...
March 11, 2017: European Journal of Nutrition
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