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bovine colostrum

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https://www.readbyqxmd.com/read/28161185/the-bovine-colostrum-microbiome-and-its-association-with-clinical-mastitis
#1
Svetlana F Lima, Andre G V Teixeira, Fabio S Lima, Erika K Ganda, Catherine H Higgins, Georgios Oikonomou, Rodrigo C Bicalho
In an effort to characterize colostrum microbial diversity and its potential associations with early-lactation clinical mastitis, we used high-throughput sequencing of the 16S rRNA gene to investigate the bovine colostrum microbiome. A prospective observational study was conducted that included 70 Holstein cows; colostrum samples were collected from all 4 mammary gland quarters. Colostrum samples were categorized according to whether the quarter was diagnosed (CMC) or not diagnosed (NCMC) with clinical mastitis during the first 30 d postpartum...
February 1, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28145111/a-comparative-glycomics-of-fat-globule-membrane-glycoconjugates-from-buffalo-bubalus-bubalis-milk-colostrum
#2
Brijesha Nagaraja, Shin-Ichiro Nishimura, Aparna H Sosalegowda
The health-promoting effects of Milk Fat Globule Membrane (MFGM) glycoconjugates has attracted curiosity especially with regard to the challenges encountered to unravel the glycan complexities of MFGM glycoproteins and glycosphingolipids. In this context, we characterized glycans present in buffalo milk and colostrum fat globule membranes by MALDI-TOF MS analysis by adopting chemoselective glycoblotting technique. Unlike human and bovine MFGM glycoproteins, the variations were obvious with respect to their number, size, heterogeneity and abundance among the samples analyzed...
February 1, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28109583/detection-of-recombinant-human-lactoferrin-and-lysozyme-produced-in-a-bitransgenic-cow
#3
Germán G Kaiser, Nicolás C Mucci, Vega González, Lourdes Sánchez, José A Parrón, María D Pérez, Miguel Calvo, Juan F Aller, Federico A Hozbor, Adrián A Mutto
Lactoferrin and lysozyme are 2 glycoproteins with great antimicrobial activity, being part of the nonspecific defensive system of human milk, though their use in commercial products is difficult because human milk is a limited source. Therefore, many investigations have been carried out to produce those proteins in biological systems, such as bacteria, yeasts, or plants. Mammals seem to be more suitable as expression systems for human proteins, however, especially for those that are glycosylated. In the present study, we developed a bicistronic commercial vector containing a goat β-casein promoter and an internal ribosome entry site fragment between the human lactoferrin and human lysozyme genes to allow the introduction of both genes into bovine adult fibroblasts in a single transfection...
March 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28088405/evaluation-of-factors-associated-with-immunoglobulin-g-fat-protein-and-lactose-concentrations-in-bovine-colostrum-and-colostrum-management-practices-in-grassland-based-dairy-systems-in-northern-ireland
#4
A Dunn, A Ashfield, B Earley, M Welsh, A Gordon, S J Morrison
The objectives of this study were to investigate colostrum feeding practices and colostrum quality on commercial grassland-based dairy farms, and to identify factors associated with colostrum quality that could help inform the development of colostrum management protocols. Over 1 yr, background information associated with dairy calvings and colostrum management practices were recorded on 21 commercial dairy farms. Colostrum samples (n = 1,239) were analyzed for fat, protein, lactose, and IgG concentration. A subset was analyzed for somatic cell count and total viable bacteria count...
March 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28072925/impact-of-low-and-high-doses-of-marbofloxacin-on-the-selection-of-resistant-enterobacteriaceae-in-the-commensal-gut-flora-of-young-cattle-discussion-of-data-from-2-study-populations
#5
Guillaume Lhermie, Véronique Dupouy, Farid El Garch, Nadine Ravinet, Pierre-Louis Toutain, Alain Bousquet-Mélou, Henri Seegers, Sébastien Assié
In the context of requested decrease of antimicrobial use in veterinary medicine, our objective was to assess the impact of two doses of marbofloxacin administered on young bulls (YBs) and veal calves (VCs) treated for bovine respiratory disease, on the total population of Enterobacteriaceae in gut flora and on the emergence of resistant Enterobacteriaceae. In two independent experiments, 48 YBs from 6 commercial farms and 33 VCs previously colostrum deprived and exposed to cefquinome were randomly assigned to one of the three groups LOW, HIGH, and Control...
January 10, 2017: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/28007592/colostrum-proinflammatory-cytokines-as-biomarkers-of-bovine-immune-response-to-bovine-tuberculosis-btb
#6
Eduardo Sánchez-Soto, Rosa Ponce-Ramos, Rodolfo Hernández-Gutiérrez, Abel Gutiérrez-Ortega, Angel H Álvarez, Moisés Martínez-Velázquez, Angel E Absalón, Pablo Ortiz-Lazareno, Alberto Limón-Flores, Ciro Estrada-Chávez, Sara E Herrera-Rodríguez
Bovine colostrum contains compounds, which provide passive immune protection from mother to newborn calves. Little is known about cytokine levels and their role in bovine colostrum. Moreover, the capacity of bovine colostrum cells to mount specific immune responses after natural exposure to bovine tuberculosis (bTB) antigens in dairy herds has not been studied, thus far. The purpose of this study was to identify biomarkers for bTB infection measurable in bovine colostrum. The present study reveals that isolated-immune colostrum cells can mount a specific immune response against bTB antigens, by measuring the novo IFN-γ release in cell culture...
December 19, 2016: Microbial Pathogenesis
https://www.readbyqxmd.com/read/27988130/rapid-assessment-of-bovine-colostrum-quality-how-reliable-are-transmission-infrared-spectroscopy-and-digital-and-optical-refractometers
#7
I Elsohaby, J T McClure, M Cameron, L C Heider, G P Keefe
The objectives of this study were to evaluate the performance of the transmission infrared (IR) spectroscopic method and digital and optical Brix refractometers for measurement of colostral IgG concentration and assessment of colostrum quality of dairy cows. Colostrum samples (n = 258) were collected from Holstein cows on 30 commercial dairy farms in Nova Scotia and Newfoundland, Canada. Colostral IgG concentrations of 255 samples were measured by the reference radial immunodiffusion (RID) assay and IR spectroscopy...
February 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/27889851/effect-of-cow-colostrum-on-the-performance-and-survival-rate-of-local-newborn-piglets-in-benin-republic
#8
Aristide Mahoutin Agbokounou, Gbênangnon Serge Ahounou, Issaka Youssao Abdou Karim, Guy Apollinaire Mensah, Bénoît Koutinhouin, Jean-Luc Hornick
The effect of bovine colostrum, including its thermally labile compounds, on the survival and growth performance of local breed piglets reared by their mother, in Benin, was evaluated over a 49-day trial. Three groups of 16 piglets, stemming from two primiparous sows belonging to a unique traditional farm, were respectively fed for the first 48 h of life with either bovine colostrum heated to 85 °C for 30 min, or thawed bovine colostrum, or colostrum from the mother. Thereafter, the animals that received bovine colostrum turned back to their mother...
February 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/27863544/effect-of-a-post-weaning-diet-supplemented-with-functional-feed-additives-on-ileal-transcriptome-activity-and-serum-cytokines-in-piglets-challenged-with-lipopolysaccharide
#9
N Bissonnette, X R Jiang, J J Matte, F Guay, G Talbot, V Bontempo, J Gong, Q Wang, M Lessard
This study evaluated the potential of a weanling diet supplemented with trace minerals, vitamins, prebiotics, essential oils, antioxidants and bovine colostrum (BC) to modulate the inflammatory response of low-weight (LW) and high-weight (HW) piglets challenged with lipopolysaccharide (LPS). At weaning (20±1 d), litters from 32 sows were assigned to four groups: control diet (CTL), CTL plus dietary supplements (DS) or the antibiotic chlortetracycline (ATB), or DS plus BC in place of plasma proteins in the weanling diet (DS+BC)...
December 2016: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/27862411/natural-and-artificial-hyperimmune-solutions-impact-on-health-in-puppies
#10
H Mila, A Grellet, C Mariani, A Feugier, B Guard, J Suchodolski, J Steiner, S Chastant-Maillard
Colostrum and milk are complex mammary secretions providing the puppy with many nutritional and immunological factors, which play a crucial role for its correct development and survival. In the case of colostrum and/or milk intake deficiency, puppies are at increased risk of infectious diseases. This work reviews the various nutritional hyperimmune supplementations proposed to provide a passive immune protection and to positively impact puppies' health. Some strategies rely on canine immunoglobulins: canine colostrum banking and canine serum/plasma supplementation...
November 15, 2016: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/27775665/the-inhibition-effect-of-cell-dna-oxidative-damage-and-ldl-oxidation-by-bovine-colostrums
#11
Chih-Wei Chen, Chi-Yue Chang, Shu-Hua Chiang
In the present study, we investigated the effect of bovine colostrums on inhibition of DNA oxidative damage and low density lipoprotein (LDL) oxidation in vitro. Results showed that whey and skimmed milk exhibited not only higher inhibitory activities of oxidative damage of deoxyribose but also an inhibitory effect on the breakdown of supercoiled DNA into open circular DNA and linear DNA. The quantities of 8-OH-2'-dG formed under whey, caseins and skimmed milk treatment were 0.24, 0.24 and 1.24 μg/mL, respectively...
October 21, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27744721/the-risks-of-using-allogeneic-cell-lines-for-vaccine-production-the-example-of-bovine-neonatal-pancytopenia
#12
Lindert Benedictus, Charlotte R Bell
Bovine neonatal pancytopenia (BNP) is a hemorrhagic disease that emerged in calves across Europe in 2007. Its occurrence is attributed to immunization of the calf's mother with a vaccine produced using an allogeneic cell line. Vaccine-induced alloantibodies specific for major-histocompatibility class I antigens are transferred from the mother to the calf via colostrum, leading to profound depletion of peripheral blood and bone marrow cells that is often fatal. Areas covered: Pubmed and Web of Science were used to search for literature relevant to BNP and the use of allogeneic vaccine cell lines...
January 2017: Expert Review of Vaccines
https://www.readbyqxmd.com/read/27727715/bovine-colostrum-plus-corticosteroids-in-treatment-of-severe-alcoholic-hepatitis-a-prospective-proof-of-concept-trial
#13
Sandeep S Sidhu, Omesh Goyal, Harsh Kishore
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27693017/standardized-bovine-colostrum-derivative-impedes-development-of-type-1-diabetes-in-rodents
#14
Ivana Nikolic, Ivana Stojanovic, Milica Vujicic, Paolo Fagone, Katia Mangano, Stanislava Stosic-Grujicic, Ferdinando Nicoletti, Tamara Saksida
Bovine colostrum is a rich source of nutrients and immunologically active components that play a role in conveying passive immunity to the offspring, protection and maturation of new-born's gastrointestinal tract. Colostrum has exerted positive effects in diseases affecting gastrointestinal tract, as well as type 2 diabetes (T2D). However, health-promoting effects in type 1 diabetes have not been reported. The aim of this study was to investigate therapeutic value of oral administration of standardized bovine colostrum derivative (SBCD) in three models of type 1 diabetes (T1D): spontaneously developed T1D in NOD mice and BB-DP rats, and in chemically induced T1D in C57BL/6 mice with multiple low doses of streptozotocin (MLDS)...
February 2017: Immunobiology
https://www.readbyqxmd.com/read/27690059/lactoferrin-from-milk-nutraceutical-and-pharmacological-properties
#15
Francesco Giansanti, Gloria Panella, Loris Leboffe, Giovanni Antonini
Lactoferrin is an iron-binding protein present in large quantities in colostrum and in breast milk, in external secretions and in polymorphonuclear leukocytes. Lactoferrin's main function is non-immune protection. Among several protective activities shown by lactoferrin, those displayed by orally administered lactoferrin are: (i) antimicrobial activity, which has been presumed due to iron deprivation, but more recently attributed also to a specific interaction with the bacterial cell wall and extended to viruses and parasites; (ii) immunomodulatory activity, with a direct effect on the development of the immune system in the newborn, together with a specific antinflammatory effects; (iii) a more recently discovered anticancer activity...
2016: Pharmaceuticals
https://www.readbyqxmd.com/read/27660754/porcine-milk-oligosaccharides-and-sialic-acid-concentrations-vary-throughout-lactation
#16
Austin T Mudd, Jaime Salcedo, Lindsey S Alexander, Stacey K Johnson, Caitlyn M Getty, Maciej Chichlowski, Brian M Berg, Daniela Barile, Ryan N Dilger
BACKGROUND: Milk oligosaccharides (OSs) are bioactive components known to influence neonatal development. These compounds have specific physiological functions acting as prebiotics, immune system modulators, and enhancing intestine and brain development. OBJECTIVES: The pig is a commonly used model for studying human nutrition, and there is interest in quantifying OS composition of porcine milk across lactation compared with human milk. In this study, we hypothesized that OS and sialic acid (SA) composition of porcine milk would be influenced by stage of lactation...
2016: Frontiers in Nutrition
https://www.readbyqxmd.com/read/27638265/effect-of-high-pressure-processing-of-bovine-colostrum-on-immunoglobulin-g-concentration-pathogens-viscosity-and-transfer-of-passive-immunity-to-calves
#17
Derek M Foster, Keith P Poulsen, Hannah J Sylvester, Megan E Jacob, Kaitlyn E Casulli, Brian E Farkas
This study aimed to determine the effects of high-pressure processing on the immunoglobulin concentration, microbial load, viscosity, and transfer of passive immunity to calves when applied to bovine colostrum as an alternative to thermal pasteurization. A pilot study using Staphylococcus aureus was conducted to determine which pressure-time treatments are most appropriate for use with bovine colostrum, with the goals of maximizing bacterial inactivation while minimizing IgG content and viscosity changes. Following the pilot study, an inoculation study was conducted in which first-milking colostrum samples from Holstein-Friesian cows were inoculated with known concentrations of various bacteria or viruses and pressure processed at either 300 MPa for up to 60min or at 400MPa for up to 30min...
November 2016: Journal of Dairy Science
https://www.readbyqxmd.com/read/27631207/effects-of-bovine-colostrum-on-recurrent-respiratory-tract-infections-and-diarrhea-in-children
#18
MULTICENTER STUDY
Khaled Saad, Mohamed Gamil M Abo-Elela, Khaled A Abd El-Baseer, Ahmed E Ahmed, Faisal-Alkhateeb Ahmad, Mostafa S K Tawfeek, Amira A El-Houfey, Mohamed Diab AboulKhair, Ahmad M Abdel-Salam, Amir Abo-Elgheit, Heba Qubaisy, Ahmed M Ali, Eman Abdel-Mawgoud
BACKGROUND: Bovine colostrum (BC) has direct antimicrobial and endotoxin-neutralizing effects throughout the alimentary tract, as well as other bioactivities that suppress gut inflammation and promote mucosal integrity and tissue repair under various conditions related to tissue injury. The precise role of BC in respiratory and gastrointestinal (GI) infections in children is not well defined. The aim of this study was to evaluate the efficacy and tolerability of BC administration in preventing recurrent upper respiratory tract infections (URTI) and diarrhea in children...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27614837/survey-of-bovine-colostrum-quality-and-hygiene-on-northern-victorian-dairy-farms
#19
A J Phipps, D S Beggs, A J Murray, P D Mansell, M A Stevenson, M F Pyman
One of the major challenges for dairy producers is to produce, harvest, and store high-quality colostrum and feed it to their replacement heifer calves. Limited published data are available in Australia regarding the relationship between colostrum management, hygiene, and quality. The objectives of this study were to investigate (1) the colostrum storage and handling practices carried out on farm; (2) the immunoglobulin concentration and bacterial composition of colostrum being fed to replacement dairy heifer calves; (3) the percentage of colostrum being fed to replacement dairy heifer calves that meet industry recommendations; and (4) risk factors for bacterial contamination of colostrum...
November 2016: Journal of Dairy Science
https://www.readbyqxmd.com/read/27601209/preferential-expression-of-ighv-and-ighd-encoding-antibodies-with-exceptionally-long-cdr3h-and-a-rapid-global-shift-in-transcriptome-characterizes-development-of-bovine-neonatal-immunity
#20
Yfke Pasman, Daniele Merico, Azad K Kaushik
With an objective to understand natural development of bovine neonatal immunity, we analyzed 18 RNA-seq libraries from peripheral blood lymphocytes of three neonatal calves pre- (day 0) and post-colostrum (7, 14 and 28) uptake as compared to their dams. A significant global shift in neonatal transcriptome occurs within first week post-birth, in contrast to dams, with an upregulation of 717 genes. Global pathway analysis of the transcriptome revealed 110 differentially expressed immune-related genes, such as, complement, MHCII, chemokine receptors, defensins and cytokines, at birth...
February 2017: Developmental and Comparative Immunology
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