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https://www.readbyqxmd.com/read/28070851/development-of-a-sustained-antiplaque-and-antimicrobial-chewing-gum-of-a-decapeptide
#1
Abeer M Al-Ghananeem, Kai P Leung, Jabar Faraj, Patrick P DeLuca
The objective of this paper was to design a chewing gum formulation delivery system in situations where typical dental hygiene practice is not practical. Thus, an analog of decapeptide KSL (KSL-W), known to possess antimicrobial and antiplaque activity, was incorporated into a chewing gum formulation containing cetylpyridinium chloride (CPC). The effect of the excipients, xylitol, and peppermint oil on active ingredients in vitro release was also assessed. Gum formulations were prepared with different excipient parameters, including heating xylitol and gum base at 65 or 85°C, using ground and unground xylitol, and the addition of 1...
January 9, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28042937/trigeminal-receptor-study-of-high-intensity-cooling-agents
#2
Sonya Johnson, Minmin Tian, Gloria Sheldon, Eric Dowd
Compounds capable of providing trigeminal effects are important to the flavor industry. Cooling agents activate a class of transient receptor potential (TRP) channels. The objective of this study was to evaluate the effect of 18 cooling agents by high-throughput screening through TRPM-8 and TRPA-1 channels. These coolants were further evaluated by a sensory analysis panel in a sucrose solution testing for a perceived activity. The results reveal that WS-5 activates both TRPA-1 and TRPM-8 receptor channels; WS-3 actives primarily TRPM-8, whereas FEMA-4557 activates the TRPA-1 channel...
January 11, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28039245/chewing-gum-for-the-treatment-of-postoperative-nausea-and-vomiting-a-pilot-randomized-controlled-trial
#3
J N Darvall, M Handscombe, K Leslie
BACKGROUND: A novel treatment, chewing gum, may be non-inferior to ondansetron in inhibiting postoperative nausea and vomiting (PONV) in female patients after laparoscopic or breast surgery. In this pilot study, we tested the feasibility of a large randomized controlled trial. METHODS: We randomized 94 female patients undergoing laparoscopic or breast surgery to ondansetron 4 mg i.v. or chewing gum if PONV was experienced in the postanaesthesia care unit (PACU)...
January 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28009052/non-pharmacological-interventions-for-alleviating-pain-during-orthodontic-treatment
#4
REVIEW
Padhraig S Fleming, Hardus Strydom, Christos Katsaros, Lci MacDonald, Michele Curatolo, Piotr Fudalej, Nikolaos Pandis
BACKGROUND: Pain is prevalent during orthodontics, particularly during the early stages of treatment. To ensure patient comfort and compliance during treatment, the prevention or management of pain is of major importance. While pharmacological means are the first line of treatment for alleviation of orthodontic pain, a range of non-pharmacological approaches have been proposed recently as viable alternatives. OBJECTIVES: To assess the effects of non-pharmacological interventions to alleviate pain associated with orthodontic treatment...
December 23, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27939912/effects-of-mastication-on-human-somatosensory-processing-a-study-using-somatosensory-evoked-potentials
#5
Hiroki Nakata, Mai Aoki, Kiwako Sakamoto
The aim of the present study was to investigate the effects of mastication on somatosensory processing using somatosensory-evoked potentials (SEPs). Fourteen healthy subjects received a median nerve stimulation at the right wrist under two conditions: Mastication and Control. SEPs were recorded in five sessions for approximately seven minutes: Pre, Post 1, 2, 3, and 4. Subjects were asked to chew gum for five minutes after one session in Mastication. Control included the same five sessions. The amplitudes and latencies of P14, N20, P25, N35, P45, and N60 components at C3', frontal N30 component at Fz, and P100 and N140 components at Pz were analyzed...
December 7, 2016: Neuroscience Research
https://www.readbyqxmd.com/read/27932815/chewing-gum-added-to-fresh-breath-kit
#6
(no author information available yet)
No abstract text is available yet for this article.
December 9, 2016: British Dental Journal
https://www.readbyqxmd.com/read/27928114/thorough-mastication-prior-to-swallowing-increases-postprandial-satiety-and-the-thermic-effect-of-a-meal-in-young-women
#7
Naho Komai, Naoko Motokubota, Maki Suzuki, Ikuyo Hayashi, Toshio Moritani, Narumi Nagai
There is evidence to support that mastication may contribute to the prevention of weight gain via reduction of appetite sensations and subsequent energy intake. However, the metabolic effect of mastication after consumption of a daily meal, composed of the staple food (rice), soup, main and side dishes, is limited. Therefore, the effect of thorough mastication on greater satiety and the thermic effect of a meal (TEM) was investigated in young women. In study 1, energy expenditure (EE) derived from masticatory muscle activity for 20 min was measured while chewing hard, tasteless, non-caloric gum in seven subjects...
2016: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/27925100/strategies-for-thirst-relief-integrative-literature-review
#8
Aline Korki Arrabal Garcia, Lígia Fahl Fonseca, Patricia Aroni, Cristina Maria Galvão
Objective: to analyze the strategies used to relieve the thirst of hospitalized patients. Method: an integrative review, for which the databases PubMed, LILACS, CINAHL and the group of references organized by the Group for Study and Research of Thirst were selected for the search of primary studies, with the keywords: thirst, ice, cold, intervention, nursing care, artificial saliva. Results: the review sample was composed of ten primary studies...
November 2016: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/27889628/effect-of-betel-nut-chewing-on-the-otolithic-reflex-system
#9
Chuan-Yi Lin, Yi-Ho Young
OBJECTIVE: This study investigated the effect of betel nut chewing on the otolithic reflex system. METHODS: Seventeen healthy volunteers without any experience of chewing betel nut (fresh chewers) and 17 habitual chewers underwent vital sign measurements, ocular vestibular-evoked myogenic potential (oVEMP), and cervical VEMP (cVEMP) tests prior to the study. Each subject then chewed two pieces of betel nut for 2min (dosing). The same paradigm was repeated immediately, 10min, and 20min after chewing...
January 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/27885554/short-term-effects-of-a-green-coffee-extract-garcinia-c-ambogia-and-l-carnitine-containing-chewing-gum-on-snack-intake-and-appetite-regulation
#10
Cecilia Bobillo, Graham Finlayson, Ana Martínez, Daniela Fischman, Analisa Beneitez, Alejandro J Ferrero, Belisario E Fernández, Marcos A Mayer
INTRODUCTION: Different studies have assessed the influence of chewing gum to aid control of appetite and reduce food intake. PURPOSE: The aims of the present study were to evaluate the effects of chewing gum on satiety, food hedonics and snack intake and to explore the potential effects of the combination of Garcinia c ambogia, green coffee extract and L-carnitine on satiety, when administered in a gum format. METHODS: This was a prospective study in which 57 subjects randomly received three kinds of treatments, in a crossover design: (1) active gum; (2) placebo gum; and (3) no gum...
November 24, 2016: European Journal of Nutrition
https://www.readbyqxmd.com/read/27875017/gum-chewing-combined-with-oral-intake-of-a-semi-liquid-diet-in-the-postoperative-care-of-patients-after-gynecologic-laparoscopic-surgery
#11
Yuping Pan, Li Chen, Xiaorong Zhong, Suwen Feng
AIM AND OBJECTIVES: To evaluate the effects of gum chewing combined with a semi-liquid diet on patients after gynecologic laparoscopic surgery. BACKGROUND: Previous studies suggested that chewing gum before traditional postoperative care promotes the postoperative recovery of bowel motility and function after open and laparoscopic surgery. However, gum chewing combined with a semi-liquid diet has not been reported in postoperative care of patients following gynecologic laparoscopic surgery...
November 22, 2016: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27834107/a-critical-review-of-the-literature-to-conduct-a-toxicity-assessment-for-oral-exposure-to-methyl-salicylate
#12
Tracy Greene, Sarah Rogers, Allison Franzen, Robinan Gentry
Methyl salicylate is the predominant constituent of oil of wintergreen and is used as a pesticide, a denaturant, an external analgesic, a fragrance ingredient, and a flavoring agent in products such as chewing gum, baked goods, syrups, candy, beverages, ice cream, and tobacco products; and it occurs naturally in some vegetables and berries. Methyl salicylate is of interest to the tobacco industry as oil of wintergreen is used as a flavorant in tobacco products. The purpose of this investigation was to conduct a critical review of the available literature for oral exposure to methyl salicylate, incorporating an analysis of the quality of the studies available and the current understanding of the mode of action...
November 11, 2016: Critical Reviews in Toxicology
https://www.readbyqxmd.com/read/27831763/thyroid-patient-salivary-radioiodine-transit-and-dysfunction-assessment-using-chewing-gums
#13
Demetrios Okkalides
Radiation-induced salivary gland dysfunction is the most frequent side-effect of I-131 thyroid therapy. Here, a novel saliva sampling method with ordinary chewing gums administered to the patients at appropriate time intervals post-treatment (TIPT) was used to relate this effect to chewing gum saliva activity (CGSA) content. Saliva samples were acquired after the oral administration of prescribed I-131 activity (radioactivity administered [RA]) to 19 differentiated thyroid cancer (DTC) and 16 hyperthyroidism patients of the radioisotope unit (RIU) during 2014 and 2015...
November 2016: Cancer Biotherapy & Radiopharmaceuticals
https://www.readbyqxmd.com/read/27829457/combined-effect-of-new-complete-dentures-and-simple-dietary-advice-on-nutritional-status-in-edentulous-patients-study-protocol-for-a-randomized-controlled-trial
#14
Yuriko Komagamine, Manabu Kanazawa, Maiko Iwaki, Ayami Jo, Hiroyuki Suzuki, Noriko Amagai, Shunsuke Minakuchi
BACKGROUND: Individuals who are edentulous have a lower intake of fruit, vegetables, fiber, and protein compared with their dentate counterparts because tooth loss is accompanied by a decrease in ability to chew. Whether or not a combination of prosthetic rehabilitation and simple dietary advice produces improvement in dietary intake among edentulous persons is unclear. We aim to investigate the effect of a simultaneous combination of simple dietary advice delivered by dentists and provision of new complete dentures on dietary intake in edentulous individuals who request new dentures...
November 9, 2016: Trials
https://www.readbyqxmd.com/read/27824974/association-between-masticatory-function-and-oral-health-related-quality-of-life-in-partial-maxillectomy-patients
#15
Mohamed Moustafa Said, Takafumi Otomaru, Yiliyaer Aimaijiang, Na Li, Hisashi Taniguchi
PURPOSE: The aim of this study was to investigate associations between objectively and subjectively measured masticatory function and oral health-related quality of life (OHRQoL) in partial maxillectomy patients wearing dentomaxillary prostheses. MATERIALS AND METHODS: A sample of 32 consecutively treated patients who had undergone a partial maxillectomy were enrolled. Masticatory function was assessed using two objective measures and one subjective measure. The objective measures were masticatory performance (MP), which was estimated by measuring the glucose extracted from gummy jelly, and food mixing ability (a*), which was assessed using color-changeable chewing gum...
November 2016: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/27798677/a-facile-method-for-separating-and-enriching-nano-and-submicron-particles-from-titanium-dioxide-found-in-food-and-pharmaceutical-products
#16
James J Faust, Kyle Doudrick, Yu Yang, David G Capco, Paul Westerhoff
Recent studies indicate the presence of nano-scale titanium dioxide (TiO2) as an additive in human foodstuffs, but a practical protocol to isolate and separate nano-fractions from soluble foodstuffs as a source of material remains elusive. As such, we developed a method for separating the nano and submicron fractions found in commercial-grade TiO2 (E171) and E171 extracted from soluble foodstuffs and pharmaceutical products (e.g., chewing gum, pain reliever, and allergy medicine). Primary particle analysis of commercial-grade E171 indicated that 54% of particles were nano-sized (i...
2016: PloS One
https://www.readbyqxmd.com/read/27794077/assessing-dna-recovery-from-chewing-gum
#17
Alison M Eychner, Kelly M Schott, Kelly M Elkins
The purpose of this study was to evaluate which DNA extraction method yields the highest quantity of DNA from chewing gum. In this study, several popular extraction methods were tested, including Chelex-100, phenol-chloroform-isoamyl alcohol (PCIA), DNA IQ, PrepFiler, and QIAamp Investigator, and the quantity of DNA recovered from chewing gum was determined using real-time polymerase chain reaction with Quantifiler. Chewed gum control samples were submitted by anonymous healthy adult donors, and discarded environmental chewing gum samples simulating forensic evidence were collected from outside public areas (e...
October 28, 2016: Medicine, Science, and the Law
https://www.readbyqxmd.com/read/27790569/association-between-chewing-side-preference-and-dental-caries-among-deciduous-mixed-and-permanent-dentition
#18
Ullal Anand Nayak, Reena Sharma, Nilotpol Kashyap, Deepesh Prajapati, Damodar Kappadi, Saakshe Wadhwa, Shina Gandotra, Poonam Yadav
INTRODUCTION: Chewing Side Preference (CSP) is said to occur when mastication is recognized exclusively/consistently or predominantly on the same side of the jaw. It can be assessed by using the direct method - visual observation and indirect methods by electric programs, such as cinematography, kinetography and computerized electromyography. AIM: The present study was aimed at evaluating the prevalence of CSP in deciduous, mixed and permanent dentitions and relating its association with dental caries...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27760896/gustatory-salivation-is-associated-with-body-mass-index-daytime-sleepiness-and-snoring-in-healthy-young-adults
#19
Satoshi Izumi, Guang Hong, Koh Iwasaki, Masayuki Izumi, Yusuke Matsuyama, Mirei Chiba, Takashi Toda, Tada-Aki Kudo
The taste detection system for oral fatty acid may be related to obesity. In addition, sleep is intrinsically and closely related to food intake and metabolism. However, the association of gustatory salivation with body mass index (BMI), daytime sleepiness, or sleep habits is largely unknown. Therefore, we evaluated the relationship between gustatory salivation and BMI, Epworth sleepiness scale (ESS, a daytime sleepiness scale) or sleep habits among 26 healthy young individuals (20 males and 6 females; mean age: 26...
2016: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/27752163/-effect-of-gum-chewing-on-bowel-function-recovery-in-patients-after-radical-cystectomy-with-urinary-diversion
#20
Y Wang, Y S Meng, Y Fan, C Chen, W Yu, H Hao, W K Han, J R Hao, J Jin, L Q Zhou
OBJECTIVE: To determine whether chewing gum during the postoperative period facilitates the recovery of bowel function in patients after radical cystectomy with ileum urinary diversion. METHODS: In the study, 60 patients who underwent radical cystectomy followed by ileum urinary diversions during Nov. 2014 and Nov. 2015 in Department of Urology of Peking University First Hospital were randomized into three groups: gum chewing group, placebo group treated with the abdomen physical therapy machine and control group treated with ordinary method...
October 18, 2016: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
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