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Ting Chen

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https://www.readbyqxmd.com/read/28230456/off-label-prescribing-for-children-with-migraines-in-u-s-ambulatory-care-settings
#1
L Leanne Lai, Leroy Koh, Jane Ai-Chen Ho, Alexander Ting, Augustine Obi
BACKGROUND: Migraines, Which Affect About 10% Of School-Age Children In The United States, Can Significantly Impair Quality Of Life. Despite Potential Disability, Many Children Do Not Receive Treatment Or Prophylaxis, Since Medications Specifically Approved For Children Are Significantly Less Than For Adults. There Is Also Controversy Surrounding The Apparent Widespread Practice Of Prescribing Off-Label Medications For Children With Migraines. However, Little Research Has Been Done To Identify Physician-Prescribing Patterns Of Migraine Medication For Children...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28228591/the-swi-snf-chromatin-regulator-brg1-modulates-the-transcriptional-regulatory-activity-of-the-ebv-dna-polymerase-processivity-factor-bmrf1
#2
Mei-Tzu Su, Ya-Ting Wang, Yen-Ju Chen, Su-Fang Lin, Ching-Hwa Tsai, Mei-Ru Chen
During lytic phase of Epstein-Barr virus (EBV), binding of the transactivator Zta to the origin of lytic replication (oriLyt) and the BHLF1 transcript, forming a stable RNA-DNA hybrid, are required to initiate viral DNA replication. EBV-encoded viral DNA replication proteins form complexes to amplify viral DNA. BMRF1, the viral DNA polymerase accessory factor, is essential for lytic DNA replication and also known as a transcriptional regulator of the expression of BHLF1 and BALF2 (ssDNA-binding protein). In order to determine systematically how BMRF1 regulates viral transcription, a BMRF1 knockout bacmid was generated to analyze viral gene expression using a viral DNA microarray...
February 22, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28228322/anti-tumour-research-of-recombinant-bcg-using-bzlf1-and-hgm-csf-fusion-genes
#3
Qing-Jie Xue, Yun-Qing Li, Chun-Qing Yang, Ting Chen, Xiu-Zhen Li, Baohua Cheng, Chun-Mei Wang
The random primer Oligo(dT)15 was used in RT-PCR to obtain cDNA from the human granulocyte macrophage colony stimulating factor (hGM-CSF) gene and the Epstein-Barr virus (EBV) gene BZLF1. Then, the sequence splicing overlap extension method was used to obtain a GCBF fusion gene containing a linker sequence that encoded the polypeptide (Gly4Ser)3. The GCBF fusion gene was inserted into pMV261, which was then transformed into competent E. coli DH5 alpha cells, and positive cells were selected based on kanamycin resistance on LB plates...
February 19, 2017: Vaccine
https://www.readbyqxmd.com/read/28225073/high-mutation-rates-explain-low-population-genetic-divergence-at-copy-number-variable-loci-in-homo-sapiens
#4
Xin-Sheng Hu, Francis C Yeh, Yang Hu, Li-Ting Deng, Richard A Ennos, Xiaoyang Chen
Copy-number-variable (CNV) loci differ from single nucleotide polymorphic (SNP) sites in size, mutation rate, and mechanisms of maintenance in natural populations. It is therefore hypothesized that population genetic divergence at CNV loci will differ from that found at SNP sites. Here, we test this hypothesis by analysing 856 CNV loci from the genomes of 1184 healthy individuals from 11 HapMap populations with a wide range of ancestry. The results show that population genetic divergence at the CNV loci is generally more than three times lower than at genome-wide SNP sites...
February 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28224728/%C3%AE-2-dependent-endocytosis-of-n-cadherin-is-regulated-by-%C3%AE-catenin-to-facilitate-neurite-outgrowth
#5
Yi-Ting Chen, Chin-Yin Tai
Circuit formation in the brain requires neurite outgrowth throughout development to establish synaptic contacts with target cells. Active endocytosis of several adhesion molecules facilitates the dynamic exchange of these molecules at the surface and promotes neurite outgrowth in developing neurons. The endocytosis of N-cadherin, a calcium-dependent adhesion molecule, has been implicated in the regulation of neurite outgrowth, but the mechanism remains unclear. Here, we identified that a fraction of N-cadherin internalizes through clathrin-mediated endocytosis (CME)...
February 22, 2017: Traffic
https://www.readbyqxmd.com/read/28224250/abscisic-acid-sucrose-and-auxin-coordinately-regulate-berry-ripening-process-of-the-fujiminori-grape
#6
Haifeng Jia, Zhenqiang Xie, Chen Wang, Lingfei Shangguan, Ning Qian, Mengjie Cui, Zhongjie Liu, Ting Zheng, Mengqi Wang, Jinggui Fang
The aim of this study was to examine the effect of abscisic acid (ABA), sucrose, and auxin on grape fruit development and to assess the mechanism of these three factors on the grape fruit ripening process. Different concentrations of ABA, sucrose, and auxin were used to treat the grape fruit, and the ripening-related indices, such as physiological and molecular level parameters, were analyzed. The activity of BG protein activity was analyzed during the fruit development. Sucrose, ABA, and auxin influenced the grape fruit sugar accumulation in different ways, as well as the volatile compounds, anthocyanin content, and fruit firmness...
February 21, 2017: Functional & Integrative Genomics
https://www.readbyqxmd.com/read/28223797/fabrication-and-in-vitro-in-vivo-evaluation-of-amorphous-andrographolide-nanosuspensions-stabilized-by-d-%C3%AE-tocopheryl-polyethylene-glycol-1000-succinate-sodium-lauryl-sulfate
#7
Hongzhi Qiao, Lihua Chen, Tianqi Rui, Jingxian Wang, Ting Chen, Tingming Fu, Junsong Li, Liuqing Di
Andrographolide (ADG) is a diterpenoid isolated from Andrographis paniculata with a wide spectrum of biological activities, including anti-inflammatory, anticancer and hepatoprotective effects. However, its poor water solubility and efflux by P-glycoprotein have resulted in lower bioavailability. In this study, ADG nanosuspensions (ADG-NS) were prepared using a wet media milling technique followed by freeze drying. d-α-Tocopheryl polyethylene glycol 1000 succinate (TPGS), a surfactant that inhibits P-glycoprotein function, and sodium lauryl sulfate were used as surface stabilizers...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28223775/a-comparison-of-three-different-corneal-marking-methods-used-to-determine-cyclotorsion-in-the-horizontal-meridian
#8
Hung-Yuan Lin, Yi-Ting Fang, Ya-Jung Chuang, Justin N Karlin, Hsin-Yang Chen, Szu-Yuan Lin, Pi-Jung Lin, Ming Chen
During toric intraocular lens (IOL) implantation, surgeons must take particular care to ensure that inaccurate preoperative measurement and intraoperative misalignment do not cause unexpected postoperative residual astigmatism. This retrospective, comparative case series study aimed to analyze the rotational deviation, or cyclotorsion, of three corneal marking methods: VERION digital marker (VDM; reference), horizontal slit beam marking (HSBM), and subjective direct visual marking (SDVM) on the table (using a bevel knife tip)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28223732/effects-of-sex-and-generation-on-hepatitis-b-viral-load-in-families-with-hepatocellular-carcinoma
#9
Ai-Ru Hsieh, Cathy Sj Fann, Chau-Ting Yeh, Hung-Chun Lin, Shy-Yi Wan, Yi-Cheng Chen, Chia-Lin Hsu, Jennifer Tai, Shi-Ming Lin, Dar-In Tai
AIM: To explore factors associated with persistent hepatitis B virus (HBV) infection in a cohort of hepatocellular carcinoma (HCC)-affected families and then investigate factors that correlate with individual viral load among hepatitis B surface antigen (HBsAg)-positive relatives. METHODS: We evaluated non-genetic factors associated with HBV replication in relatives of patients with HCC. Relatives of 355 HCC cases were interviewed using a structured questionnaire...
February 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28223085/self-perception-of-weight-status-and-its-association-with-weight-related-knowledge-attitudes-and-behaviors-among-chinese%C3%A2-children-in-guangzhou
#10
Li Cai, Ting Zhang, Jun Ma, Lu Ma, Jin Jing, Yajun Chen
BACKGROUND: How weight perception influences weight-related knowledge, attitudes, and behaviors in Chinese children is unknown. We investigated self-perception of body weight and its correlates, and analyzed the relationship between weight perception and weight-related knowledge, attitudes, and behaviors in children in Guangzhou, China. METHODS: We assessed self-reported weight perception, weight-related knowledge, attitudes, and behaviors in 3752 children aged 7-12 years...
February 17, 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/28223011/extracorporeal-membrane-oxygenation-support-in-neonates-a-single-medical-center-experience-in-taiwan
#11
Chi-Man Kuok, Po-Nien Tsao, Chien-Yi Chen, Hung-Chieh Chou, Wu-Shiun Hsieh, Shu-Chien Huang, Yih-Sharng Chen, En-Ting Wu
BACKGROUND: Extracorporeal membrane oxygenation (ECMO) was used in neonates with severe cardiopulmonary failure who failed to respond to conventional therapy. We started to apply neck venoarterial ECMO (VA-ECMO) in neonatal patients from 2000. In this study, we have focused on neonates who received ECMO support and described the current status of ECMO in neonates for both cardiac and pulmonary support and the risk factors associated with their outcomes. METHODS: Data were retrieved from our ECMO database for the neonates (age < 28 days) who received neck VA-ECMO support from January 2005 to June 2015...
January 17, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/28222497/correction-lapatinib-inhibits-cip2a-pp2a-p-akt-signaling-and-induces-apoptosis-in-triple-negative-breast-cancer-cells
#12
Chun-Yu Liu, Ming-Hung Hu, Chia-Jung Hsu, Chun-Teng Huang, Duen-Shian Wang, Wen-Chun Tsai, Yi-Ting Chen, Chia-Han Lee, Pei-Yi Chu, Chia-Chi Hsu, Ming-Huang Chen, Chung-Wai Shiau, Ling-Ming Tseng, Kuen-Feng Chen
No abstract text is available yet for this article.
February 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/28221901/prevalence-and-persistence-of-listeria-monocytogenes-in-ready-to-eat-tilapia-sashimi-processing-plants
#13
Bang-Yuan Chen, Chung-Yi Wang, Chia-Lan Wang, Yang-Chi Fan, I-Ting Weng, Chung-Hsi Chou
A 2-year study was performed at two ready-to-eat tilapia sashimi processing plants (A and B) to identify possible routes of contamination with Listeria monocytogenes during processing. Samples were collected from the aquaculture environments, transportation tanks, processing plants, and final products. Seventy-nine L. monocytogenes isolates were found in the processing environments and final products; 3.96% (50 of 1,264 samples) and 3.86% (29 of 752 samples) of the samples from plants A and B, respectively, were positive for L...
November 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28221381/enhanced-photocatalytic-activities-of-single-crystalline-znga2o4-nanoprisms-by-the-coexposed-111-and-110-facets
#14
Tingting Zheng, Yuguo Xia, Xiuling Jiao, Ting Wang, Dairong Chen
Facet-control has been a fascinating method for preparation of highly active photocatalysts. Herein, we report the hydrothermal preparation of single-crystalline ZnGa2O4 nanoprisms with the {111} and {110} facets coexposed. Studies of their photocatalytic performance have revealed that the as-formed nanoprisms exhibit significantly enhanced photocatalytic activities compared with ZnGa2O4 nanocubes with only the {100} facets exposed and nanosheets with the {110} facets exposed for H2 evolution and contaminant degradation...
February 21, 2017: Nanoscale
https://www.readbyqxmd.com/read/28220881/use-of-selective-serotonin-reuptake-inhibitors-in-the-first-trimester-and-risk-of-cardiovascular-related-malformations-a-meta-analysis-of-cohort-studies
#15
Tie-Ning Zhang, Shan-Yan Gao, Zi-Qi Shen, Da Li, Cai-Xia Liu, Hai-Chen Lv, Yuan Zhang, Ting-Ting Gong, Xin Xu, Chao Ji, Qi-Jun Wu
The relationship between selective serotonin-reuptake inhibitors (SSRIs) use during first trimester and cardiovascular-related malformations of infants is still uncertain. Therefore, we conducted this systematic review and meta-analysis to assess the aforementioned association. A systematic literature review identified studies for cohort studies about SSRIs use and cardiovascular-related malformations in PubMed and Web of Science. We summarized relative risk (RRs) and 95% confidence intervals (CIs) of cardiovascular-related malformations using random-effects model, and heterogeneity and publication-bias analyses were conducted...
February 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28220480/quality-and-stability-of-extemporaneous-pyridoxal-phosphate-preparations-used-in-the-treatment-of-paediatric-epilepsy
#16
Abeer H A Mohamed-Ahmed, Matthew P Wilson, Maedelyn Albuera, Ting Chen, Philippa B Mills, Emma J Footitt, Peter T Clayton, Catherine Tuleu
OBJECTIVES: To assess the pyridoxal 5'-phosphate (PLP) content and stability of extemporaneous PLP liquids prepared from dietary supplements used for the treatment of vitamin B6 -dependent epilepsy. METHODS: Pyridoxal 5'-phosphate liquids were prepared in accordance with the guidelines given to patients from marketed 50 mg PLP dietary capsules and tablets. The PLP content and its stability were evaluated under conditions resembling the clinical setting using reverse phase HPLC and mass spectrometry...
February 21, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28219681/the-developmental-relationship-between-central-dopaminergic-level-and-response-inhibition-from-late-childhood-to-young-adulthood
#17
Ting Zhang, Qin Zhang, Cuicui Wang, Antao Chen
Dopamine (DA) is known to modulate response inhibition (RI). In contrast to the abundant adult studies, only few developmental studies have focused on this topic. Moreover, the mechanism underlying the modulation of RI by the DA system from childhood to adulthood remains unclear. We aimed to assess whether the relationship between DA and RI during late childhood and young adulthood is similar. Accordingly, DA function was measured using the spontaneous eye blink rate (EBR), whereas RI ability was tested using the Go/Nogo task...
February 17, 2017: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/28218703/phenolic-acid-profiling-antioxidant-and-anti-inflammatory-activities-and-mirna-regulation-in-the-polyphenols-of-16-blueberry-samples-from-china
#18
Xianming Su, Jian Zhang, Hongqing Wang, Jing Xu, Jiuming He, Liying Liu, Ting Zhang, Ruoyun Chen, Jie Kang
To investigate the anti-atherosclerosis related mechanism of blueberries, the phenolic acids (PAs) content, antioxidant and anti-inflammatory activities, as well as the microRNA (miRNA) regulation of polyphenol fractions in blueberry samples from China were studied. Sixteen batches of blueberries including 14 commercialized cultivars (Reka, Patriot, Brigitta, Bluecrop, Berkeley, Duke, Darrow, Northland, Northblue, Northcountry, Bluesource, Southgood, O'Neal, and Misty) were used in this study. Seven PAs in the polyphenol fractions from 16 blueberry samples in China were quantified by high performance liquid chromatography/tandem mass spectrometry (HPLC/MS²)...
February 18, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28218577/prognostic-role-of-plasma-epstein-barr-virus-dna-load-for-nasopharyngeal-carcinoma-a-meta-analysis
#19
Ting-Bo Liu, Zhi-Hong Zheng, Jie Pan, Li-Li Pan, Li-Hong Chen
PURPOSE: Predicting prognosis and treatment outcomes for patients with for nasopharyngeal carcinoma (NPC) has been difficult due to the heterogeneous nature of the disease This study aimed to evaluate pretreatment copy number of plasma Epstein-Barr virus (EBV) DNA as an outcome marker for survival in NPC. METHODS: MEDLINE, CENTRAL and Embase databases were searched until April 7, 2015. Included studies were randomized controlled trials, two-arm prospective studies, or retrospective studies in patients with newly diagnosed NPC...
February 19, 2017: Clinical and Investigative Medicine. Médecine Clinique et Experimentale
https://www.readbyqxmd.com/read/28216639/discrete-element-model-for-suppression-of-coffee-ring-effect
#20
Ting Xu, Miu Ling Lam, Ting-Hsuan Chen
When a sessile droplet evaporates, coffee-ring effect drives the suspended particulate matters to the droplet edge, eventually forming a ring-shaped deposition. Because it causes a non-uniform distribution of solid contents, which is undesired in many applications, attempts have been made to eliminate the coffee-ring effect. Recent reports indicated that the coffee-ring effect can be suppressed by a mixture of spherical and non-spherical particles with enhanced particle-particle interaction at air-water interface...
February 20, 2017: Scientific Reports
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