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https://www.readbyqxmd.com/read/29342321/contributions-of-material-properties-and-structure-to-increased-bone-fragility-for-a-given-bone-mass-in-the-ucd-t2dm-rat-model-of-type-2-diabetes
#1
Claire Acevedo, Meghan Sylvia, Eric Schaible, James L Graham, Kimber L Stanhope, Lionel N Metz, Bernd Gludovatz, Ann V Schwartz, Robert O Ritchie, Tamara N Alliston, Peter J Havel, Aaron J Fields
Adults with type 2 diabetes (T2D) have a higher fracture risk for a given bone quantity, but the mechanisms remain unclear. Using a rat model of polygenic obese T2D, we demonstrate that diabetes significantly reduces whole-bone strength for a given bone mass (micro-CT-derived BMC), and we quantify the roles of T2D-induced deficits in material properties versus bone structure, i.e., geometry and microarchitecture. Lumbar vertebrae and ulnae were harvested from 6-month-old lean Sprague-Dawley rats, obese Sprague-Dawley rats, and diabetic obese UCD-T2DM rats (diabetic for 69 ± 7 days; blood glucose >200 mg/dl)...
January 17, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29332662/a-survivorship-study-of-838-total-elbow-replacements-a-report-from-the-norwegian-arthroplasty-register-1994-2016
#2
Yngvar Krukhaug, Geir Hallan, Eva Dybvik, Stein A Lie, Ove N Furnes
BACKGROUND: The aim of this study was to present the long-term survivorship (20 years) of total elbow arthroplasty (TEA) for a relatively large population and to compare different prosthesis brands and patient subgroups. METHODS: Between 1994 and 2017, a total of 838 primary TEAs were reported to the Norwegian Arthroplasty Register. Implant survival was calculated using the Kaplan-Meier method. Risk differences were examined using Cox regression analyses and exact Cox regression for rare events...
February 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29331298/spatiotemporal-characterization-of-microdamage-accumulation-in-rat-ulnae-in-response-to-uniaxial-compressive-fatigue-loading
#3
Xuhui Zhang, Xiyu Liu, Zedong Yan, Jing Cai, Fei Kang, Shuai Shan, Pan Wang, Mingming Zhai, X Edward Guo, Erping Luo, Da Jing
Repetitive fatigue loading can induce microdamage accumulation in bone matrix, which results in impaired mechanical properties and increased fracture susceptibility. However, the spatial distribution and time-variant process of microdamage accumulation in fatigue-loaded skeleton, especially for linear microcracks which are known to initiate bone remodeling, remain not fully understood. In this study, the time-varying process of the morphology and distribution of microcracks in rat ulnae subjected to uniaxial compressive fatigue loading was investigated...
January 10, 2018: Bone
https://www.readbyqxmd.com/read/29327558/-modified-osteotomy-of-olecranon-for-the-management-of-inter-condylar-fracture-of-the-humerus
#4
Zheng-Feng Mei, Wen-Tao Lei, Dong-Hui Huang, Qi-Hui Zhao, Hang-Bo Qu, Lian-Zhi Ni
OBJECTIVE: To explore the surgical method and clinical outcome of modified osteotomy of olecranon for the treatment of inter-condylar fracture of humerus. METHODS: From May 2007 to December 2012, 32 patients of intercondylar fracture of humerus were treated surgically through the approach of modified osteotomy of olecranon. The patients were 21 males and 11 females with a mean age of 46.3 years (ranged 18 to 65 years). Nineteen fractures occurred on the right extremity and 13 on the left extremity...
January 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29327549/-characteristics-and-treatments-of-the-essex-lopresti-injury
#5
Ming-Liang Li, Jian-Shui Mao, Chong-Bin Zhou, Ji-Wei Wang, Zhi-Jun Ye
OBJECTIVE: To summarize experiences of operative treatment for Essex-Lopresti injury, and analyze the effect of the compare repair of interosseous membrane of forearm(IOM)on the forearm function. METHODS: Twenty-four patients of Essex-Lopresti injury were treated from January 2005 to December 2013, 16 patients(group A) with radius and/or ulna fractures were treated with open reduction and internal fixation of radius or ulna and repair of forearm bone membrane at the same time, and then treated with open reduction and internal fixation of head of radius, as well as lower ulnar joint fixation or repair of wrist triangle fiber complex...
January 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29326760/both-bone-forearm-fractures-in-children-with-minimum-four-years-of-growth-remaining-can-cast-achieve-a-good-outcome-at-skeletal-maturity
#6
D Hadizie, I Munajat
Introduction: Both-bone forearm fractures in children can be treated non-operatively with a cast. Most previous studies have shown favourable outcome; however, information on the functional outcome after skeletal maturity is still scanty. Therefore, this study was conducted to determine the functional outcome after skeletal maturity in fractures with at least four years of growth remaining. Materials and Methods: This retrospective study was conducted from March 2012 until March 2013. Age at the time of fracture was taken as until 10 years for females and until 12 years old for males with at least four years of growth remaining...
November 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/29319350/biomechanical-evaluation-of-standard-versus-extended-proximal-fixation-olecranon-plates-for-fixation-of-olecranon-fractures
#7
Allison L Boden, Charles A Daly, Poonam P Dalwadi, Stephanie A Boden, William C Hutton, Raghuveer C Muppavarapu, Michael B Gottschalk
BACKGROUND: Small olecranon fractures present a significant challenge for fixation, which has resulted in development of plates with proximal extension. Olecranon-specific plates with proximal extensions are widely thought to offer superior fixation of small proximal fragments but have distinct disadvantages: larger dissection, increased hardware prominence, and the increased possibility of impingement. Previous biomechanical studies of olecranon fracture fixation have compared methods of fracture fixation, but to date there have been no studies defining olecranon plate fixation strength for standard versus extended olecranon plates...
January 1, 2018: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/29310414/left-extensive-infection-in-the-forearm-caused-by-whitlow-infected-by-mycobacterium-tuberculosis-a-case-report
#8
Tao Wang, Gang Zhao, Yong-Jun Rui, Zheng-Feng Lu, Jing-Yi Mi
INTRODUCTION: Whitlow is a common disease in clinic, characterized by pain and swelling of finger. However, few articles had reported on extensive infection in the forearm caused by whitlow infected by mycobacterium tuberculosis (MTB). PATIENT CONCERNS: A 70-year-old Chinese female complained of fester in back of left hand for 5 days. She had a history of recurrent whitlow for 14 months and pulmonary tuberculosis (TB). She received treatment in another hospital due to whitlow on July 2016...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29307065/metals-in-bones-of-the-middle-aged-inhabitants-of-sardinia-island-italy-to-assess-nutrition-and-environmental-exposure
#9
Beatrice Bocca, Giovanni Forte, Valentina Giuffra, Rita Maria Serra, Yolande Asara, Cristiano Farace, Marco Milanese, Eugenia Tognotti, Andrea Montella, Pasquale Bandiera, Roberto Madeddu
Metals in bones of 72 subjects lived between the twelfth and eighteenth century AC and collected in four Sardinian (Italian insular region) burial sites (Alghero, Bisarcio, Geridu, and Sassari) were determined and used as biomarkers to evaluate diet and potential social-environmental differences. Concentrations of Ba, Ca, Cd, Cu, Hg, Pb, Sr, and Zn were quantified in different types of compact bone (femur, fibula, humerus, radius, tibia, ulna) by sector field inductively coupled plasma mass spectrometry previous acidic digestion and differences among the various burial sites, centuries, types of bone, gender, and age were explored by univariate and multivariate analyses...
January 6, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29283018/a-practical-clinical-kinematic-model-for-the-upper-limbs
#10
Jonathan J Noble, Nicola Rd Fry, Carly R Bingham, Rebecca H East, Adam P Shortland
A novel clinically practical upper limb model is introduced that has been developed through clinical use in children and adults with neurological conditions to guide surgery to the elbow and wrist. This model has a minimal marker set, minimal virtual markers, and no functional joint centres to minimise the demands on the patient and duration of data collection. The model calculates forearm supination independently from the humerus segment, eliminating any errors introduced by poor modelling of the shoulder joint centre...
December 1, 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/29274395/adherence-to-mediterranean-diet-and-nutritional-status-in-a-sample-of-nonagenarians
#11
Guglielmo Bonaccorsi, Chiara Lorini, Francesca Santomauro, Francesco Sofi, Federica Vannetti, Guido Pasquini, Claudio Macchi
OBJECTIVE: The aim is to describe the adherence to Mediterranean diet in a sample of nonagenarians and to analyse its cross-sectional association with anthropometric and bioelectrical parameters. DESIGN: A cross-sectional design was employed in this study. The adherence to the Mediterranean diet was measured through the Mediterranean Diet Score (MedDietScore). SETTING AND PARTICIPANTS: A representative sample of nonagenarian residents in the eight municipalities belonging to Mugello (Florence, Italy)...
December 20, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/29242786/radius-and-ulna-stress-fractures-in-a-patient-with-neuromyelitis-optica-a-case-report
#12
George J M Hourston, Hadyn K N Kankam, Phillip Johnston
Introduction: Stress fractures are more common in the weight-bearing bones of the lower limb and are particularly prevalent in athletes. Whereas, those of the upper limb are usually reported as unique events in rare circumstances. Case Report: We present a case of a 40-year-old White British female with neuromyelitis optica (NMO) who mobilized in a wheelchair and presented to our center in April 2016 with a week-long history of a hot, swollen, and unstable right forearm...
September 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29241814/a-new-method-to-locate-the-radial-head-safe-zone-on-computed-tomography-axial-views
#13
Y Zhan, C F Luo, Y J Chen
PURPOSE: Direct location of a "safe zone" on a CT axial view is inadequate because the radial head is circular in shape. Previous "safe zone" location methods are not appropriate if the physician is unable to visualize the actual radial head. This study aims to introduce a new method to locate the "safe zone" on CT. METHODS: CT scans were performed on 20 intact cadaveric upper limbs from 20 different corpses in full pronation and supination. The DICOM-format raw data were then re-sliced and analyzed in Mimics 17...
December 11, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29224947/functional-outcomes-of-compression-plating-and-bone-grafting-for-operative-treatment-of-nonunions-about-the-forearm
#14
Deirdre K Regan, Alexander M Crespo, Sanjit R Konda, Kenneth A Egol
PURPOSE: To describe one center's experience with nonunion of one or both bones of the forearm and report on the functional recovery of patients treated for a single- or 2-bone forearm nonunion. METHODS: We performed a retrospective analysis of 23 patients who presented to our institution over an 11-year period and underwent surgical repair of a forearm nonunion (radius, ulna, or both bones). The main outcome measurements included time to union, visual analog scale pain scores, range of motion, Short Musculoskeletal Function Assessment scores, and postoperative complications...
December 7, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29214010/giant-cell-tumour-of-the-distal-radius-ulna-response-to-pre-operative-treatment-with-short-term-denosumab
#15
Catherine L McCarthy, Christopher L M H Gibbons, Kevin M Bradley, A Bass Hassan, Henk Giele, Nicholas A Athanasou
Background: Treatment of giant cell tumour of bone (GCTB) of the distal radius/ulna poses a surgical challenge, as complex reconstructive surgery may be required. This study evaluates the clinical, radiological and pathological findings in five cases of GCTB of the distal forearm where a 3 month course of denosumab was given prior to surgery. Methods: Patients with biopsy proven distal forearm GCTB, treated for 3 months with denosumab, followed by salvage surgery (curettage and cementation) were included...
2017: Clinical Sarcoma Research
https://www.readbyqxmd.com/read/29213017/topographical-anatomy-of-the-pronator-teres-muscle-and-median-nerve-a-study-using-histological-sections-of-human-fetuses
#16
Shinichi Abe, Naomitsu Tomita, Masahito Yamamoto, Minako Sato, Hiroshi Abe, Gen Murakami, Jose Francisco Rodríguez-Vázquez
The median nerve passes through the humeral and ulnar heads of the pronator teres muscle (PT), although variations such as absence of the ulnar head may exist. We observed histological sections of the upper extremity from 24 embryos and fetuses. In the early stage, the PT extended between the radius and the medial epicondyle of the humerus, but no candidate for the ulnar head was found. In mid-term fetuses, the ulnar margin of the PT was attached to the elbow joint capsule. Moreover, in late-stage fetuses, a small deep part of the PT arose from the thick joint capsule of the humero-ulnar joint near the coronoid process of the ulna...
2017: Okajimas Folia Anatomica Japonica
https://www.readbyqxmd.com/read/29201306/analysis-of-radiographic-parameters-of-the-forearm-in-traumatic-radial-head-dislocation
#17
Hui Taek Kim, Le Viet Can, Tae Young Ahn, In Hee Kim
Background: Various deformities can occur in the forearm bones when the traumatically dislocated radial head is untreated for a long period. Without correction of all deformities, reduction of the dislocated radial head is difficult to maintain, and forearm and elbow motion will deteriorate after reduction. We evaluated radiographic parameters of forearms with traumatically dislocated radial heads (and of the normal sides) to understand the resulting deformities and the effectiveness of surgical treatment...
December 2017: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/29200488/a-newly-designed-intramedullary-nail-for-the-treatment-of-diaphyseal-forearm-fractures-in-adults
#18
Ibrahim Azboy, Abdullah Demirtaş, Celil Alemdar, Mehmet Gem, Kadir Uzel, Huseyin Arslan
Background: The treatment of diaphyseal forearm fractures using open reduction and plate fixation is generally accepted as the best choice in many studies. However, periosteal stripping, haematoma evacuation may result in delayed union, nonunion and infection. Refracture after plate removal is another concern. To overcome these problems intramedullary nails (IM) with different designs have been used with various outcomes. However previous IM nails have some shortcomings such is rotational instability and interlocking difficulties...
November 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29195009/ontogeny-of-surface-texture-of-limb-bones-in-modern-aquatic-birds-and-applicability-of-textural-ageing
#19
Junya Watanabe
Despite its importance in various disciplines, a general method to assess ontogenetic ages of skeletal and fossil specimens has been lacking for birds. Although the textural ageing method was formulated to assess relative ontogenetic ages of specimens from inspection of bone surface textures, the exact correspondence of surface textures to ontogenetic stages has not yet been clear. In this study, bone surface textures of six major limb bones (humerus, ulna, carpometacarpus, femur, tibiotarsus, and tarsometatarsus) were described in postnatal ontogenies of four species of modern birds (Calonectris leucomelas, Phalacrocorax capillatus, Larus crassirostris, and Cerorhinca monocerata) from 14-28 individuals of known ontogenetic stages for each species...
December 1, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29193820/osteology-and-radiological-anatomy-of-the-thoracic-limbs-of-temminck-s-ground-pangolin-smutsia-temminckii
#20
Christine Steyn, John T Soley, Martina R Crole
Temminck's ground pangolin is the only pangolin present in South Africa. It is a myrmecophagous mammal with a bipedal gait. The thoracic limbs are used to break open ant nests, dig for food, and expand previously occupied burrows. This study describes the osteology and radiological anatomy of the thoracic limbs of this threatened species. Thoracic limbs from four Temminck's ground pangolins, which succumbed from electrocution or natural causes, were digitally radiographed in situ. The individual bones were then cleaned, described and digitally radiographed...
November 28, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
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