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https://www.readbyqxmd.com/read/29663140/poorly-differentiated-ductal-adenocarcinoma-of-the-pancreas-with-rapid-progression-in-a-young-man
#1
Koji Tezuka, Tomoharu Ishiyama, Akiko Takeshita, Hidekazu Matsumoto, Akira Jingu, Jiro Kikuchi, Hideyuki Yamaya, Rintaro Ohe, Tetsuya Ishizawa
Pancreatic cancer in young adults is very rare. We report a case of young-onset poorly differentiated pancreatic ductal adenocarcinoma with rapid progression and poor prognosis in a 31-year-old Japanese man with no obvious family history of malignancy. Preoperative examinations revealed a mass lesion in the body of the pancreas, accompanied by a slightly dilated main pancreatic duct distal to the mass lesion. Pancreatic cancer with acute pancreatitis was suspected because of an elevation of serum pancreatic enzyme and tumor marker, along with imaging findings...
April 16, 2018: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/29656597/splenic-artery-as-a-simple-landmark-indicating-difficulty-during-laparoscopic-distal-pancreatectomy
#2
Yoshiya Ishikawa, Daisuke Ban, Shuichi Watanabe, Keiichi Akahoshi, Hiroaki Ono, Yusuke Mitsunori, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe
INTRODUCTION: The use of laparoscopic distal pancreatectomy (LDP) is increasing worldwide. It is important for surgeons to predict preoperatively the difficulty and risks of a surgery. However, very few reports have evaluated the impact of patient or tumor factors on the difficulty of LDP. We aimed to determine the predictors of technical difficulties when performing LDP. METHODS: This study included 34 patients who underwent LDP. Patient information was obtained retrospectively and included age, gender, BMI, primary disease, previous abdominal surgery, previous pancreatitis, tumor size, tumor proximity to the splenic arterial origin, type of splenic artery (SpA), operative time, blood loss, postoperative pancreatic fistula, and length of hospital stay...
April 15, 2018: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/29650928/-conversion-surgery-after-etoposide-cisplatin-ep-therapy-for-huge-pancreatic-neuroendocrine-carcinoma-a-case-report
#3
Akiko Nakazawa, Tetsuya Mitsui, Yoichi Miyata, Riki Ninomiya, Masahiko Komagome, Akira Maki, Fumiaki Ozawa, Yoshifumi Beck
Neuroendocrine carcinoma(NEC)is known as rapid tumor growth, high grade malignancy and poor prognosis. We report a case of huge pancreatic NEC successfully performed conversion surgery after EP therapy. A 70-year-old female, was presented to our hospital with appetite loss. CT scan revealed huge tumor, 15 cm in diameter, locating at the pancreas with possible involvement to liver, stomach, common hepatic artery, left gastric artery and gastroduodenal artery. Peritoneal dissemination and para-aortic lymph node metastasis were also suspected...
March 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29650321/a-novel-pipeline-for-adrenal-tumour-segmentation
#4
Hasan Koyuncu, Rahime Ceylan, Hasan Erdogan, Mesut Sivri
BACKGROUND AND OBJECTIVE: Adrenal tumours occur on adrenal glands surrounded by organs and osteoid. These tumours can be categorized as either functional, non-functional, malign, or benign. Depending on their appearance in the abdomen, adrenal tumours can arise from one adrenal gland (unilateral) or from both adrenal glands (bilateral) and can connect with other organs, including the liver, spleen, pancreas, etc. This connection phenomenon constitutes the most important handicap against adrenal tumour segmentation...
June 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29650056/pancreatoduodenectomy-with-or-without-prophylactic-falciform-ligament-wrap-around-the-gastroduodenal-artery-stump-for-prevention-of-pancreatectomy-hemorrhage
#5
Benjamin Müssle, Leonie Zühlke, Ann Wierick, Dorothée Sturm, Xina Grählert, Marius Distler, Nuh N Rahbari, Jürgen Weitz, Thilo Welsch
BACKGROUND: The purpose of this study is to evaluate whether wrapping of the pedicled falciform ligamentum flap around the gastroduodenal artery (GDA) stump/hepatic artery can significantly decrease the incidence of erosion hemorrhage after pancreatoduodenectomy (PD). METHODS/DESIGN: This is a randomized controlled multicenter trial involving 400 patients undergoing PD. Patients will be randomized into two groups. The intervention group consists of 200 patients with a prophylactic wrapping of the GDA stump using the pedicled falciform ligament...
April 12, 2018: Trials
https://www.readbyqxmd.com/read/29649954/anatomical-considerations-and-open-surgery-to-treat-juxtarenal-abdominal-aortic-aneurysms
#6
Georgiana Samoila, Ian Michael Williams
INTRODUCTION: Historically, the open approach to the abdominal aorta has been transperitoneal (TP). In comparison, a retroperitoneal (RP) incision exposes the lateral wall of the suprarenal aorta for clamp application and midline structures such as the duodenum and pancreas are not encountered. Proximal clamp position for open repair of juxtarenal abdominal aortic aneurysm (JR-AAA) is suprarenal, supra-superior mesenteric, or supraceliac. While RP and TP approaches have previously been compared for physiological reasons, there are currently no randomized controlled trials comparing these methods from an anatomical perspective...
January 1, 2018: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29628495/pancreaticoduodenectomy-with-preservation-of-collateral-circulation-or-revascularization-for-biliary-pancreatic-cancer-with-celiac-axis-occlusion-a-report-of-2-cases
#7
Kazuaki Shibuya, Hirofumi Kamachi, Tatsuya Orimo, Akihisa Nagatsu, Shingo Shimada, Kenji Wakayama, Hideki Yokoo, Toshiya Kamiyama, Akinobu Taketomi
BACKGROUND In cases of celiac axis occlusion requiring pancreaticoduodenectomy for malignancy, both oncologic curability and control of hepatic arterial flow must be considered, but the operative strategy is undeveloped. CASE REPORT Case 1: A 74-year-old man was diagnosed with hilar cholangiocarcinoma with celiac axis stenosis. The collateral from the superior mesenteric artery ran through the pancreas head but no invasion was observed in preoperative imaging. Hepatopancreatoduodenectomy with preservation of a collateral was performed...
April 9, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29625745/evaluation-of-a-single-pass-with-biphasic-intravenous-contrast-medium-injection-ct-protocol-for-the-assessment-of-complications-post-simultaneous-pancreas-kidney-transplant
#8
D Y-F Chung, E M Anderson
AIM: To evaluate the use of a single-pass with biphasic intravenous contrast medium injection computed tomography (CT) protocol to provide diagnostic quality CT studies for the assessment of complications post-simultaneous pancreas-kidney transplant (SPK). MATERIALS AND METHODS: This was an audit of practice and the need for informed consent was waived. The protocol was used in consecutive patients undergoing CT to exclude intra-abdominal sepsis post-SPK between June and December 2015...
April 3, 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29620617/pancreas-transplantation-from-pediatric-donors-a-single-center-experience
#9
Mario Spaggiari, Caterina Di Bella, Pierpaolo Di Cocco, Maya Campara, Kelly Galen, Federico Gheza, Jose Oberholzer, Enrico Benedetti, Ivo Tzvetanov
BACKGROUND: Pancreas allografts from pediatric donors are considered less suitable due to the increased risk of surgical complications and reduced islet cell mass that may compromise function. METHODS: All pancreatic transplants, procured from donors <18 years old, between January 2007 and March 2017, were included in the analysis. The grafts were subdivided into 3 groups by donor's weight: <30kg, 30-60kg, >60kg. Analysis of patient and graft survival was done between the groups, and subsequently between the pediatric cohort and the adult-donor control group...
April 3, 2018: Transplantation
https://www.readbyqxmd.com/read/29616107/awareness-of-hepatic-arterial-variants-is-required-in-surgical-oncology-decision-making-strategy-case-report-and-review-of-literature
#10
Robert Sitarz, Monika Berbecka, Jerzy Mielko, Karol Rawicz-Pruszyński, Grzegorz Staśkiewicz, Ryszard Maciejewski, Wojciech Polkowski
Surgery for the treatment of pancreatic cancer remains the gold standard, however, the identification of the vascular supply of the pancreas and the nearby organs remains a crucial difficulties in a curative resection. During pancreatic head resection for carcinoma dissection of regional arterial vasculature is mandatory. Normal coeliac and hepatic arterial anatomy occurs in ~50-70% of patients and multiple variations have been described. Knowledge of multiple arterial anomalies is essential in hepato-pancreatico-billary surgery to avoid unnecessary complications...
May 2018: Oncology Letters
https://www.readbyqxmd.com/read/29605904/three-dimensional-computer-assisted-dissection-of-pancreatic-lymphatic-anatomy-on-human-fetuses-a-step-toward-automatic-image-alignment
#11
T Bardol, G Subsol, M-J Perez, D Genevieve, A Lamouroux, B Antoine, G Captier, M Prudhomme, M M Bertrand
PURPOSE: Pancreatic cancer is the fourth cause of death by cancer worldwide. Lymph node (LN) involvement is known to be the main prognostic factor. However, lymphatic anatomy is complex and only partially characterized. The aim of the study was to study the pancreatic lymphatic system using computer-assisted anatomic dissection (CAAD) technique and also to update CAAD technique by automatizing slice alignment. METHODS: We dissected three human fetuses aged from 18 to 34 WA...
March 31, 2018: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/29594467/pancreatic-neuroendocrine-tumor-review-of-heterogeneous-spectrum-of-ct-appearance
#12
REVIEW
Nam Ju Lee, Ralph H Hruban, Elliot K Fishman
OBJECTIVE: Pancreatic neuroendocrine tumors (PanNETs) are uncommon pancreatic neoplasms and can be a diagnostic challenge with heterogeneous spectrum of CT appearance. We review CT findings of PanNETs and other mimics. CONCLUSION: PanNETs are typically hypervascular and have avid enhancement on arterial and venous phase images. However, dedicated pancreas protocol may be needed due to their sometimes atypical appearance including transient enhancement. Careful evaluation of CT findings will help differentiate PanNETs from their mimics, and can be used to establish the diagnosis of a PanNETs...
March 28, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29582129/evaluating-the-feasibility-of-isolated-pancreatic-perfusion-for-chemotherapy-using-computed-tomography-an-experimental-study-in-pig-models
#13
Satoru Murata, Shiro Onozawa, Daisuke Yasui, Tatsuo Ueda, Fumie Sugihara, Akira Shimizu, Kenichi Suzuki, Mitsuo Satake
PURPOSE: Percutaneous isolated pancreatic perfusion (PIPP) is performed along with interventional radiology techniques to obtain high drug concentration by occluding the arterial inlet and venous outlet of the pancreas. The experimental study aimed to evaluate the contrast distribution in PIPP under different flow rates with or without anterior mesenteric artery (AMA) occlusion. MATERIALS AND METHODS: This study was approved by a local animal experiment ethics committee...
March 26, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29564566/impact-of-continuous-regional-arterial-infusion-in-the-treatment-of-acute-necrotizing-pancreatitis-analysis-of-a-national-administrative-database
#14
Akira Endo, Atsushi Shiraishi, Kiyohide Fushimi, Kiyoshi Murata, Yasuhiro Otomo
BACKGROUND: Although continuous regional arterial infusion (CRAI) of protease inhibitors and broad antibiotics has been suggested as one of the therapeutic option for patients with acute necrotic pancreatitis (ANP), the effectiveness has not been well-corroborated in clinical studies. METHODS: We conducted a retrospective cohort study using a Japanese national administrative database. Severe acute pancreatitis patients with a poorly enhanced pancreas region (i.e...
March 21, 2018: Journal of Gastroenterology
https://www.readbyqxmd.com/read/29561447/situs-inversus-totalis-with-solid-pseudopapillary-pancreatic-tumor-a-case-report-and-review-of-literature
#15
Deng Xiang, Jiannan He, Zimeng Fan, Fangfang Xiong, Gang Liu, Sufen Chen, Wu Wen, Jianfeng Li, Junhua Ai, Renhua Wan, Gongxian Wang, Jun Shi
RATIONALE: Situs inversus totalis (SIT) is a rare anatomical variation of the internal organs, and solid pseudopapillary tumor of the pancreas (SPTP) is a rare tissue type of pancreatic tumors, classified as benign or low-grade malignancy. However, to our knowledge, a patient with SIT and SPTP is extremely rare and has never been reported. PATIENT CONCERNS: We retrospectively analyzed a case of SIT with SPTP in a 45-year-old woman. The main complaints were abdominal pain and sensation of heaviness for 2 weeks...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29560005/pancreaticoduodenectomy-for-an-ampullary-region-carcinoma-occurred-in-annular-pancreas-coexistent-with-replaced-common-hepatic-artery
#16
Ryuji Komine, Atsushi Shimizu, Kazuhiko Mori, Keisuke Minamimura, Toru Hirata, Takashi Kobayashi, Nobuo Toda, Masaya Mori
Introduction: Annular pancreas is a rare congenital abnormality characterized by a ring of pancreatic tissue surrounding the descending portion of the duodenum. Annular pancreas coexisting with replaced common hepatic artery which is also a rare anatomical variation has not been reported previously. Case Presentation: A 53-year-old man visited our hospital complaining of epigastric pain. Based on radiological examinations, he was diagnosed as having pancreatitis, annular pancreas, and hepatomesenteric trunk...
2018: Case Reports in Medicine
https://www.readbyqxmd.com/read/29558711/pancreas-sparing-and-superior-mesenteric-artery-first-approach-in-duodenal-adenocarcinoma-of-the-fourth-portion-of-duodenum-a-case-report
#17
Marie-Julie Lardinois, Nicolas Meurisse
INTRODUCTION: Peroperative assessment of resectability in pancreas-sparing duodenectomy for distal duodenal (D3-D4) adenocarcinoma is challenging for surgeons. PRESENTATION OF CASE: We report a 68-year-old man with biopsy-proven adenocarcinoma of the fourth portion of duodenum which had been diagnosed with upper endoscopy and CT. A pancreas-sparing duodenectomy with loco-regional lymph node resection using the superior mesenteric artery first approach was performed...
March 9, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29552341/irreversible-electroporation-of-locally-advanced-solid-pseudopapillary-carcinoma-of-the-pancreas-a-case-report
#18
Luciano Tarantino, Aurelio Nasto, Giuseppina Busto, Vincenzo Iovino, Raffaele Fristachi, Sara Bortone
Introduction: Solid pseudopapillary Carcinoma (SPC) is a rare pancreatic Tumor with variable, usually low, malignancy potential. Howewer, several SPC are associated with aggressive behavior, local vascular infiltration, organ invasion, distant metastasis, and can be unresectable. Irreversible Electroporation (IRE) is an emerging non-thermal ablation technique for the treatment of locally advanced pancreatic carcinoma. We report the results of four year disease-free follow-up in a case of locally advanced unresectable SPC treated with IRE...
April 2018: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/29534407/-application-of-preset-adaptive-statistical-iterative-reconstruction-v-in-dual-enhanced-abdominal-ct
#19
Y R Chai, J J Xing, J B Gao, P J Lü, P Hou, J Liu
Objective: To analyze the effect of preset adaptive statistical iterative reconstruction-V (ASIR-V) on image quality and radiation dose in dual-enhanced abdominal CT and to investigate the optimal ASIR-V in clinic use. Methods: From February 13 to April 30 in 2017, one hundred and eighty patients who received up abdominal CT scan in the First Affiliated Hospital of Zhengzhou University were collected prospectively. All patients underwent arterial phase (AP) and portal venous phase (PVP) enhanced abdominal CT(120 kVp, noise index 10) and were randomly divided into 6 groups according to random number table (A-F, 30 cases in each group)...
March 6, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29527509/diabetic-muscle-infarction-in-end-stage-renal-disease-a-scoping-review-on-epidemiology-diagnosis-and-treatment
#20
REVIEW
Tuck Yean Yong, Kareeann Sok Fun Khow
Diabetic muscle infarction (DMI) refers to spontaneous ischemic necrosis of skeletal muscle among people with diabetes mellitus, unrelated to arterial occlusion. People with DMI may have coexisting end-stage renal disease (ESRD) but little is known about its epidemiology and clinical outcomes in this setting. This scoping review seeks to investigate the characteristics, clinical features, diagnostic evaluation, management and outcomes of DMI among people with ESRD. Electronic database (PubMed/MEDLINE, CINAHL, SCOPUS and EMBASE) searches were conducted for ("diabetic muscle infarction" or "diabetic myonecrosis") and ("chronic kidney disease" or "renal impairment" or "dialysis" or "renal replacement therapy" or "kidney transplant") from January 1980 to June 2017...
March 6, 2018: World Journal of Nephrology
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