Paul J Young, Carol L Hodgson, Diane Mackle, Anne M Mather, Richard Beasley, Rinaldo Bellomo, Stephen Bernard, Kathy Brickell, Adam M Deane, Glenn Eastwood, Simon Finfer, Alisa M Higgins, Anna Hunt, Cassie Lawrence, Natalie J Linke, Edward Litton, Christine F McDonald, James Moore, Alistair D Nichol, Shaanti Olatunji, Rachael L Parke, Sandra Peake, Paul Secombe, Ian M Seppelt, Anne Turner, Tony Trapani, Andrew Udy, Jessica Kasza
BACKGROUND: The effect of conservative vs. liberal oxygen therapy on outcomes of intensive care unit (ICU) patients with hypoxic ischaemic encephalopathy (HIE) is uncertain and will be evaluated in the Low Oxygen Intervention for Cardiac Arrest injury Limitation (LOGICAL) trial. OBJECTIVE: The objective of this study was to summarise the protocol and statistical analysis plans for the LOGICAL trial. DESIGN SETTING AND PARTICIPANTS: LOGICAL is a randomised clinical trial in adults in the ICU who are comatose with suspected HIE (i...
September 2023: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine