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https://www.readbyqxmd.com/read/28091442/fluoride-release-recharging-ability-and-bond-strength-of-glass-ionomer-cements-to-sound-and-caries-affected-dentin
#1
E Kucukyilmaz, S Savas, F Kavrik, B Yasa, M S Botsali
OBJECTIVES: The aim of this in vitro study was to evaluate the microtensile bond strength (μTBS) of different glass ionomer cements (GICs) on sound/caries-affected dentin and to assess the fluoride release/recharging ability. METHODS: After creating artificial caries lesions, teeth with sound and caries-affected dentin were assigned to be restored with one of the GICs: Ketac N100; GC Equia; GCP Glass Fill, and tested using a microtensile test. Ten of each material were prepared, and fluoride ion-release was measured at 10 different intervals...
February 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28087597/membrane-depolarizing-channel-blockers-induce-selective-glioma-cell-death-by-impairing-nutrient-transport-and-unfolded-protein-amino-acid-responses
#2
Mia Niklasson, Gianluca Maddalo, Zuzana Sramkova, Ercan Mutlu, Shimei Wee, Petra Sekyrova, Linnéa Schmidt, Nicolas Fritz, Ivar Dehnisch, Gregorios Kyriatzis, Michaela Krafcikova, Brittany B Carson, Jennifer Feenstra, Voichita D Marinescu, Anna Segerman, Martin Haraldsson, Anna-Lena Gustavsson, Lars Gj Hammarström, Annika Jenmalm-Jensen, Lene Uhrbom, A F Maarten Altelaar, Sten Linnarsson, Per Uhlén, Lukas Trantirek, C Theresa Vincent, Sven Nelander, Per Øyvind Enger, Michael Andäng
Glioma-initiating cells (GIC) are considered the underlying cause of recurrences of aggressive glioblastomas, replenishing the tumor population and undermining the efficacy of conventional chemotherapy. Here we report the discovery that inhibiting T-type voltage-gated Ca2+ and KCa channels can effectively induce selective cell death of GIC and increase host survival in an orthotopic mouse model of human glioma. At present, the precise cellular pathways affected by the drugs affecting these channels are unknown...
January 13, 2017: Cancer Research
https://www.readbyqxmd.com/read/28081569/gender-incongruence-of-childhood-clinical-utility-and-stakeholder-agreement-with-the-world-health-organization-s-proposed-icd-11-criteria
#3
Titia F Beek, Peggy T Cohen-Kettenis, Walter P Bouman, Annelou L C de Vries, Thomas D Steensma, Gemma L Witcomb, Jon Arcelus, Christina Richards, Griet De Cuypere, Baudewijntje P C Kreukels
The World Health Organization (WHO) is revising the tenth version of the International Classification of Diseases and Related Health Problems (ICD-10). This includes a reconceptualization of the definition and positioning of Gender Incongruence of Childhood (GIC). This study aimed to: 1) collect the views of transgender individuals and professionals regarding the retention of the diagnosis; 2) see if the proposed GIC criteria were acceptable to transgender individuals and health care providers; 3) compare results between two countries with two different healthcare systems to see if these differences influence opinions regarding the GIC diagnosis; and 4) determine whether healthcare providers from high-income countries feel that the proposed criteria are clinically useful and easy to use...
2017: PloS One
https://www.readbyqxmd.com/read/28076496/evaluation-of-dentin-hypersensitivity-treatment-with-glass-ionomer-cements-a-randomized-clinical-trial
#4
Marina de Matos Madruga, Adriana Fernandes da Silva, Wellington Luiz de Oliveira da Rosa, Evandro Piva, Rafael Guerra Lund
A randomized, double-blind, split-mouth clinical trial was performed compared the desensitizing efficacy of the resin-modified glass ionomer cement (GIC) ClinproTM XT (3M ESPE, Minnesota, USA) and the conventional GIC Vidrion R (SS White, Gloucester, UK) in a 6-month follow-up. Subjects were required to have at least two teeth with dentin hypersensitivity. Teeth were divided at random into 2 groups, one group received Clinpro XT and the other conventional GIC Vidrion R. Treatments were assessed by tactile and air blast tests using Visual Analogue Scale (VAS) at baseline, after 20 minutes, and at 7, 15, 21, 30, 90 and 180 days post-treatment...
January 5, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28065528/a-comprehensive-evaluation-of-the-gastrointestinal-tract-in-iron-deficiency-anemia-with-predefined-hemoglobin-below-9mg-dl-a-prospective-cohort-study
#5
Xavier Bosch, Elisabet Montori, Mar Guerra-García, Jaime Costa-Rodríguez, Mariano H Quintanilla, Paula E Tolosa-Chapasian, Pedro Moreno, Neus Guasch, Alfons López-Soto
BACKGROUND: Anemia is defined as hemoglobin below the cutoff of normal in studies examining the gastrointestinal (GI) tract in iron-deficiency anemia (IDA). Although the risk of GI cancer (GIC) increases as hemoglobin decreases, guidelines do not usually recommend hemoglobin thresholds for IDA investigation. METHODS: To elucidate whether underlying GI disorders explain the different hemoglobin values and clinical outcomes observed initially in IDA patients referred for GI workup, we prospectively investigated the diagnostic yield of a thorough GI examination in consecutive IDA adults with predefined hemoglobin <9g/dL and no extraintestinal bleeding...
December 21, 2016: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28056537/local-and-widely-distributed-eeg-activity-in-schizophrenia-with-prevalence-of-negative-symptoms
#6
Vera A Grin-Yatsenko, Valery A Ponomarev, Marina V Pronina, Yury I Poliakov, Irina V Plotnikova, Juri D Kropotov
We evaluated EEG frequency abnormalities in resting state (eyes closed and eyes open) EEG in a group of chronic schizophrenia patients as compared with healthy subjects. The study included 3 methods of analysis of deviation of EEG characteristics: genuine EEG, current source density (CSD), and group independent component (gIC). All 3 methods have shown that the EEG in schizophrenia patients is characterized by enhanced low-frequency (delta and theta) and high-frequency (beta) activity in comparison with the control group...
January 1, 2017: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
https://www.readbyqxmd.com/read/28043087/long-term-treatment-outcomes-in-immature-permanent-teeth-by-revascularisation-using-mta-and-gic-as-canal-sealing-materials-a-retrospective-study
#7
Chufang Peng, Yuan Yang, Yuming Zhao, He Liu, Zheng Xu, Dianhong Zhao, Man Qin
BACKGROUND: Pulp revascularisation with MTA sealing has been accepted as an alternative treatment for non-vital immature permanent teeth. Successful revascularisation cases with GIC sealing were also reported, but lack of long-term researches. AIM: To evaluate long-term outcomes of revascularisation using MTA and GIC as canal-sealing materials in non-vital immature permanent teeth. DESIGN: Clinical and radiographic data of 60 non-vital immature permanent teeth treated with revascularisation (36...
January 2, 2017: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/28028417/a-twofold-comparison-between-dual-cure-resin-modified-cement-and-glass-ionomer-cement-for-orthodontic-band-cementation
#8
Hanaa El Attar, Omnia Elhiny, Ghada Salem, Ahmed Abdelrahman, Mazen Attia
AIM: To test the solubility of dual cure resin modified resin cement in a food simulating solution and the shear bond strength compared to conventional Glass ionomer cement. MATERIALS AND METHOD: The materials tested were self-adhesive dual cure resin modified cement and Glass Ionomer (GIC). Twenty Teflon moulds were divided into two groups of tens. The first group was injected and packed with the modified resin cement, the second group was packed with GIC. To test the solubility, each mould was weighed before and after being placed in an analytical reagent for 30 days...
December 15, 2016: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28013413/selective-persistence-of-propionibacterium-species-fma5-following-sealing-of-infected-dentinal-matrix
#9
M A Nadkarni, K Angner, N Hunter
The objective of the present study was to test the hypothesis that nutrient deprivation by effective isolation should inactivate causative saccharolytic bacteria occupying carious lesions. Vital maxillary third molar teeth were prepared by removing only the superficial necrotic material, leaving behind infected dentinal matrix, before the cavity was sealed with glass ionomer cement (GIC). Before sealing, lesions were biopsied to provide reference bacterial DNA for microbial analysis. After an interval of 10-12 months, the teeth were extracted and, after careful removal of GIC restoration, the underlying dentine was biopsied again for post-treatment microbial analysis...
December 24, 2016: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/27974212/clonal-variation-in-drug-and-radiation-response-among-glioma-initiating-cells-is-linked-to-proneural-mesenchymal-transition
#10
Anna Segerman, Mia Niklasson, Caroline Haglund, Tobias Bergström, Malin Jarvius, Yuan Xie, Ann Westermark, Demet Sönmez, Annika Hermansson, Marianne Kastemar, Zeinab Naimaie-Ali, Frida Nyberg, Malin Berglund, Magnus Sundström, Göran Hesselager, Lene Uhrbom, Mats Gustafsson, Rolf Larsson, Mårten Fryknäs, Bo Segerman, Bengt Westermark
Intratumoral heterogeneity is a hallmark of glioblastoma multiforme and thought to negatively affect treatment efficacy. Here, we establish libraries of glioma-initiating cell (GIC) clones from patient samples and find extensive molecular and phenotypic variability among clones, including a range of responses to radiation and drugs. This widespread variability was observed as a continuum of multitherapy resistance phenotypes linked to a proneural-mesenchymal shift in the transcriptome. Multitherapy resistance was associated with a semi-stable cell state that was characterized by an altered DNA methylation pattern at promoter regions of mesenchymal master regulators and enhancers...
December 13, 2016: Cell Reports
https://www.readbyqxmd.com/read/27965490/comparison-of-the-solubility-of-conventional-luting-cements-with-that-of-the-polyacid-modified-composite-luting-cement-and-resin-modified-glass-lonomer-cement
#11
Reshma Karkera, A P Nirmal Raj, Lijo Isaac, Mohammed Mustafa, R Naveen Reddy, Mathew Thomas
INTRODUCTION: This study was planned to find the solubility of the conventional luting cements in comparison with that of the polyacid-modified composite luting cement and recently introduced resin-modified glass ionomer cement (RMGIC) with exposure to water at early stages of mixing. MATERIALS AND METHODS: An in vitro study of the solubility of the following five commercially available luting cements, viz., glass ionomer cement (GIC) (Fuji I, GC), zinc phosphate (Elite 100, GC), polyacid-modified resin cement (PMCR) (Principle, Dentsply), polycarboxylate cement (PC) (Poly - F, Dentsply), RMGIC (Vitremer, 3M), was conducted...
December 1, 2016: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/27956016/low-cost-gics-reduce-survival-rate-in-occlusal-art-restorations-in-primary-molars-after-one-year-a-rct
#12
Isabel Cristina Olegário, Anna Luisa de Brito Pacheco, Mariana Pinheiro de Araújo, Nathalia de Miranda Ladewig, Clarissa Calil Bonifácio, José Carlos Pettorossi Imparato, Daniela Prócida Raggio
INTRODUCTION: The high costs of the worldwide recommended GICs might be a barrier for the implementation of ART. To overcome this problem, low cost GIC are used even though there is a lack of evidence for the survival rate of restorations. OBJECTIVES: To evaluate the performance of low-cost GICs used on occlusal ART restorations after one year. METHODS: A total of 150 primary molars in 150 children with occlusal caries lesions were selected in 4-8 year-old children...
December 9, 2016: Journal of Dentistry
https://www.readbyqxmd.com/read/27955690/chd7-promotes-proliferation-of-neural-stem-cells-mediated-by-mif
#13
Shigeki Ohta, Tomonori Yaguchi, Hironobu Okuno, Hervé Chneiweiss, Yutaka Kawakami, Hideyuki Okano
Macrophage migration inhibitory factor (MIF) plays an important role in supporting the proliferation and/or survival of murine neural stem/progenitor cells (NSPCs); however, the downstream effectors of this factor remain unknown. Here, we show that MIF increases the expression of Pax6 and Chd7 in NSPCs in vitro. During neural development, the chromatin remodeling factor Chd7 (chromatin helicase-DNA-binding protein 7) is expressed in the ventricular zone of the telencephalon of mouse brain at embryonic day 14...
December 13, 2016: Molecular Brain
https://www.readbyqxmd.com/read/27942546/the-effect-of-lucite-glass-reinforcement-on-the-properties-of-conventional-glass-ionomer-filling-materials
#14
Haleh Kazemi Yazdi, Richard Van Noort, Mona Mansouri
STATEMENT OF THE PROBLEM: The usage of glass ionomer cements (GICs) restorative materials are very limited due to lack of flexural strength and toughness. PURPOSE: The aim of this study was to investigate the effect of using a leucite glass on a range of mechanical and optical properties of commercially available conventional glass ionomer cement. MATERIALS AND METHOD: Ball milled 45μm leucite glass particles were incorporated into commercial conventional GIC, Ketac-Molar Easymix (KMEm)...
December 2016: Journal of Dentistry
https://www.readbyqxmd.com/read/27939657/prevention-of-secondary-caries-using-silver-diamine-fluoride-treatment-and-casein-phosphopeptide-amorphous-calcium-phosphate-modified-glass-ionomer-cement
#15
Irene Shuping Zhao, May Lei Mei, Michael F Burrow, Edward Chin-Man Lo, Chun-Hung Chu
OBJECTIVE: To study the effect of silver diamine fluoride (SDF) treatment and incorporating casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) into a glass-ionomer cement (GIC) to prevent secondary caries. METHOD: A cervical cavity was prepared on 32 premolars for the following restoration groups: group 1, conventional GIC restoration; group 2, SDF (38%) treatment and conventional GIC restoration; group 3, CPP-ACP (3%) modified GIC; and group 4, SDF treatment and CPP-ACP modified GIC...
December 6, 2016: Journal of Dentistry
https://www.readbyqxmd.com/read/27935662/antibacterial-activity-of-glass-ionomer-cement-modified-by-zinc-oxide-nanoparticles
#16
Patrícia Petromilli Nordi Sasso Garcia, Mariana Florian Bell Cardia, Renata Serignoli Francisconi, Lívia Nordi Dovigo, Denise Madalena Palomari Spolidório, Alessandra Nara de Souza Rastelli, Ana Carolina Botta
This study evaluated the antibacterial activity of zinc oxide nanoparticles incorporated into self-cured glass ionomer cement (GIC) and light-cured resin-reinforced GIC on Streptococcus mutans biofilm. The GICs, Fuji II (GC America) and Fuji II LC (GC America), were incorporated with nanoparticles at concentrations of 0%, 1%, and 2% by weight, and the biofilm maturation time was one and seven days. Circular specimens of each GIC type were prepared. The antibacterial activity was evaluated by determining the number of colony forming units of S...
December 9, 2016: Microscopy Research and Technique
https://www.readbyqxmd.com/read/27914669/effect-of-different-thermo-light-polymerization-on-flexural-strength-of-two-glass-ionomer-cements-and-a-glass-carbomer%C3%A2-cement
#17
Kristina Gorseta, Ali Borzabadi-Farahani, Alireza Moshaverinia, Domagoj Glavina, Edward Lynch
STATEMENT OF PROBLEM: Whether polymerization lights can be used for heating glass ionomer cements (GICs) or glass carbomer (GCP) to improve their mechanical properties is not well established. PURPOSE: The purpose of this in vitro study was to assess the effect of thermo-light polymerization on the flexural strength (FS) of 2 GICs (Fuji IX GP Fast, Ketac Molar) and a GCP. MATERIAL AND METHODS: Specimens (n=10) were prepared in stainless steel molds (2×2×25 mm), compressed, exposed to 3 polymerization lights (500, 1000, 1200 mW/cm(2)) for 2 cycles of 40 seconds on each side, and stored in petroleum jelly (37°C, 24 hours)...
November 30, 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/27864970/color-stability-of-dental-restorative-materials-submitted-to-heat-sources-for-forensic-purposes
#18
Roberto Cesar Biancalana, Sergio Augusto de Freitas Vicente, Ricardo Henrique Alves da Silva, Fernanda de Carvalho Panzeri Pires-de-Souza
During postmortem examination of the dental arches of carbonized victims, dental restorative materials may be found. The aim of this study was to evaluate the effect of heat source action on the color stability of composite resin (CR) and glass ionomer cement (GIC) restorations, to discriminate between them and compare with antemortem dental data. Sixty bovine teeth (30 CR and 30 GIC) were prepared (6 × 6 × 2 mm) and separated into groups (n = 10). The color readouts were taken by spectrophotometer, before and after heat action (100°C, 200°C, 300°C), in an oven for 15 min...
November 16, 2016: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/27859981/influence-of-acceleration-setting-reaction-by-halogen-light-curing-on-gic-dentin-interface-qualitative-analysis-by-sem
#19
Laysa Yoshioka, Tamara Kerber Tedesco, Ana Flávia Bissoto Calvo, Sabrina Sun Ha Kim, Anna Paula Vieira Ferreira Prado Malagrana, Daniela Prócida Raggio
The aim of this study was to evaluate by scanning electron microscope (SEM) photomicrographs the influence of application of halogen light-curing for fastening the set reaction of high-viscosity glass ionomer cements (GIC) by assessing the material/dentin interface. Twelve human primary canines were assigned in four groups (n = 3) according to the GIC (Fuji IX, GC or Maxxion R, FGM) and application of halogen light-curing (60 sec or control-no external energy). Blocks with approximately 6 mm of height were buildup on previously pre-treated dentin surface in according to the experimental group...
November 17, 2016: Microscopy Research and Technique
https://www.readbyqxmd.com/read/27847749/comparative-assessment-of-antibacterial-activity-of-different-glass-ionomer-cements-on-cariogenic-bacteria
#20
Rahul Gaybarao Naik, Arun Suresh Dodamani, Mahesh Ravindra Khairnar, Harish Chaitram Jadhav, Manjiri Abhay Deshmukh
OBJECTIVES: Glass ionomer cements (GICs), which are biocompatible and adhesive to the tooth surface, are widely used nowadays for tooth restoration. They inhibit the demineralization and promote the remineralization of the tooth structure adjacent to the restoration, as well as interfere with bacterial growth. Hence, the present study was conducted to assess and compare the antimicrobial activity of three commercially available GICs against two cariogenic bacteria. MATERIALS AND METHODS: An agar plate diffusion test was used for evaluating the antimicrobial effect of three different GICs (Fuji IX, Ketac Molar, and d-tech) on Streptococcus mutans (S...
November 2016: Restorative Dentistry & Endodontics
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