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https://www.readbyqxmd.com/read/28816187/comparison-of-film-thickness-of-two-commercial-brands-of-glass-lonomer-cement-and-one-dual-cured-composite-an-in-vitro-study
#1
Rajat R Khajuria, Rishav Singh, Pranamee Barua, Nausheen Hajira, Naveen Gupta, Rohit R Thakkar
AIM: The present study is undertaken to examine the film thickness of three most commonly used luting cements and to determine their usage as a luting agent. MATERIALS AND METHODS: This study was carried out strictly according to the guidelines of American Dental Association (ADS) specification no. 8. Two glass slabs of 5 cm in length and 2 cm in width were used. One glass slab was kept over the other glass slab and the space between the two glass slabs was measured using metallurgical microscope at the power of 10*...
August 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28806850/the-global-initiative-for-children-s-surgery-optimal-resources-for-improving-care
#2
Laura F Goodman, Etienne St-Louis, Yasmine Yousef, Maija Cheung, Benno Ure, Doruk Ozgediz, Emmanuel Adoyi Ameh, Stephen Bickler, Dan Poenaru, Keith Oldham, Diana Farmer, Kokila Lakhoo
No abstract text is available yet for this article.
August 14, 2017: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28790108/cyclophilin-a-maintains-glioma-initiating-cell-stemness-by-regulating-wnt-%C3%AE-catenin-signaling
#3
Guangzhi Wang, Jia Shen, Jiahang Sun, Zhenfeng Jiang, Jiabing Fan, Hongjun Wang, Shan Yu, Yu Long, Yi Liu, HOngbo Bao, Kelvin X Zhang, Ke Han, Min-Wei Zhu, Yongri Zheng, Zhiguo Lin, Chuanlu Jiang, Mian Guo
PURPOSE: Glioma-initiating cells (GICs) are glioma stem-like cells that contribute to glioblastoma (GBM) development, recurrence, and resistance to chemotherapy and radiotherapy. They have recently become the focus of novel treatment strategies. Cyclophilin A (CypA) is a cytosolic protein that belongs to the peptidyl-prolyl isomerase (PPIase) family and the major intracellular target of the immunosuppressive drug cyclosporin A (CsA). In this study, we investigate the functions of CypA and its mechanism of action in GICs' development...
August 8, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28789518/theranostic-iron-oxide-gold-ion-nanoprobes-for-mr-imaging-and-noninvasive-rf-hyperthermia
#4
Sajid Fazal, Bindhu Paul-Prasanth, Shantikumar V Nair, Deepthy Menon
This work focuses on the development of a nanoparticulate system that can be used for magnetic resonance (MR) imaging and E-field noninvasive radiofrequency (RF) hyperthermia. For this purpose, an amine-functional gold ion complex (GIC), [Au(III)(diethylenetriamine)Cl]Cl2, which generates heat upon RF exposure, was conjugated to carboxyl-functional poly(acrylic acid)-capped iron-oxide nanoparticles (IO-PAA NPs) to form IO-GIC NPs of size ∼100 nm. The multimodal superparamagnetic IO-GIC NPs produced T2-contrast on MR imaging and unlike IO-PAA NPs generated heat on RF exposure...
August 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28783130/shear-bond-strength-and-remineralisation-effect-of-a-casein-phosphopeptide-amorphous-calcium-phosphate-modified-glass-ionomer-cement-on-artificial-caries-affected-dentine
#5
Irene Shuping Zhao, May Lei Mei, Zhuo Long Zhou, Michael Francis Burrow, Edward Chin-Man Lo, Chun-Hung Chu
This study investigated the effect of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP)-modified glass ionomer cement (GIC) on shear bond strength (SBS) and remineralisation of artificial "caries-affected" dentine. Human dentine slices were demineralised and allocated to three groups: group 1, conventional GIC; group 2, CPP-ACP-modified GIC; and group 3, resin-modified GIC. The SBS was measured using a universal testing machine (n = 16 per group). Remaining samples (n = 8 per group) were subjected to pH-cycling for 28 days...
August 7, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28774841/antibacterial-glass-ionomer-cement-restorative-materials-a-critical-review-on-the-current-status-of-extended-release-formulations
#6
REVIEW
Tahereh Mohammadi Hafshejani, Ali Zamanian, Jayarama Reddy Venugopal, Zahra Rezvani, Farshid Sefat, Mohammad Reza Saeb, Henri Vahabi, Payam Zarrintaj, Masoud Mozafari
Glass-ionomer cements (GICs) have been widely used for over forty years, because of their desirable properties in dentistry. The most important advantages of the GICs are associated with their ability to release long-term antimicrobial agents. However, GICs used as restorative materials have still lots of challenges due to their secondary caries and low mechanical properties. Recent studies showed that the fluoride-releasing activity of conventional GICs is inadequate for effectual antibacterial conservation in many cases...
July 31, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28772386/influence-of-porous-spherical-shaped-hydroxyapatite-on-mechanical-strength-and-bioactive-function-of-conventional-glass-ionomer-cement
#7
Szu-Yu Chiu, Yukari Shinonaga, Yoko Abe, Kyoko Harada, Kenji Arita
Glass-ionomer-cement (GIC) is helpful in Minimal Intervention Dentistry because it releases fluoride ions and is highly biocompatible. The aim of this study is to investigate the mechanisms by which hydroxyapatite (HAp) improves the mechanical strength and bioactive functioning of GIC when these materials are combined to make apatite ionomer cement (AIC). A conventional GIC powder was mixed with porous, spherical-HAp particles (HApS), crystalline HAp (HAp200) or one of two types of cellulose. The micro-compressive strengths of the additive particles were measured, and various specimens were evaluated with regard to their compressive strengths (CS), fluoride release concentrations (fluoride electrode) and multi-element release concentrations...
January 3, 2017: Materials
https://www.readbyqxmd.com/read/28762350/comparative-evaluation-of-microleakage-between-bulk-esthetic-materials-versus-resin-modified-glass-ionomer-to-restore-class-ii-cavities-in-primary-molars
#8
Vellore Kannan Gopinath
AIM: The aim of the study was to assess the microleakage of one high-viscosity conventional glass ionomer cement (GIC) and a bulk-fill composite resin, in comparison to a resin-modified GIC in Class II restorations in primary molars. MATERIALS AND METHOD: Standardized Class II slot cavity preparations were prepared in exfoliating primary molars. Teeth were restored using one of the three materials tested (n = 10): SonicFill bulk-fill composite resin (SF), EQUIA Fil conventional reinforced GIC (EQF), and Vitremer resin-reinforced GIC (VT)...
July 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28759777/color-stability-of-dental-restorative-materials-submitted-to-cold-temperatures-for-forensic-purposes
#9
Roberto Cesar Biancalana, Sergio Augusto Freitas Vincenti, Ricardo Henrique Alves da Silva, Fernanda Carvalho Panzeri Pires-de-Souza
In the post-mortem examination of the dental arches of accident victims in cold locations, dental restorative materials can be found. Cold temperatures can be capable of causing color changes of aesthetic materials, such as composite resin (CR) and glass ionomer cement (GIC). The aim of this study was to evaluate the effect of the cold action on the color stability of CR and GIC restorations, in order to discriminate them and enable the adequate comparison between antemortem and post-mortem data. Sixty bovine teeth (30 CR and 30 GIC) were prepared (6 × 6 × 2 mm) and separated into groups (n = 10)...
July 25, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28754720/tert-promoter-hypermethylation-in-gastrointestinal-cancer-a-potential-stool-biomarker
#10
Li Liu, Cheng Liu, Omid Fotouhi, Yidong Fan, Kun Wang, Chuanyou Xia, Benkang Shi, Guangyong Zhang, Kexin Wang, Feng Kong, Catharina Larsson, Sanyuan Hu, Dawei Xu
BACKGROUND: There is a high demand for noninvasive screening tools for gastrointestinal cancer (GIC) detection, and GIC-specific markers are required for such purposes. It is established that induction of the telomerase reverse transcriptase gene (TERT) coupled with telomerase activation is essential for cancer development/progression and aberrant TERT promoter methylation of specific 5'-C-phosphate-G-3' (CpGs) has been linked to TERT induction in oncogenesis. Here we analyzed TERT promoter methylation in fecal samples from GIC patients and healthy adults and determined its value as a stool biomarker for GIC detection...
July 28, 2017: Oncologist
https://www.readbyqxmd.com/read/28753997/effects-of-chlorhexidine-encapsulated-mesoporous-silica-nanoparticles-on-the-anti-biofilm-and-mechanical-properties-of-glass-ionomer-cement
#11
Huiyi Yan, Hongye Yang, Kang Li, Jian Yu, Cui Huang
One of the primary causes for the failure of glass ionomer cement (GIC) is secondary caries. To enhance the anti-microbial performance of GIC without affecting its mechanical properties, chlorhexidine (CHX) was encapsulated in expanded-pore mesoporous silica nanoparticles (pMSN) to synthesize CHX@pMSN. CHX@pMSN was added at three mass fractions (1%, 5%, and 10% (w/w)) to GIC powder as the experimental groups. Pure GIC was set as the control group. The mechanical and anti-biofilm properties of GIC from each group were tested...
July 21, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28752870/endothelium-induced-three-dimensional-invasion-of-heterogeneous-glioma-initiating-cells-in-a-microfluidic-coculture-platform
#12
Yuta Chonan, Sotaro Taki, Oltea Sampetrean, Hideyuki Saya, Ryo Sudo
Glioblastoma (GBM) is a highly invasive primary brain tumor that displays cellular heterogeneity, which is composed of glioma initiating cells (GICs) and their differentiated progeny. GICs play an important role in driving aggressive invasion. In particular, the interaction between GICs and blood vessels is critical because blood vessels are known to serve as routes for the invasion of GICs. However, the effect of endothelial cells on the three-dimensional (3D) invasion process of GICs as well as the spatial relationship between GICs and their differentiated progeny remains unclear...
July 28, 2017: Integrative Biology: Quantitative Biosciences From Nano to Macro
https://www.readbyqxmd.com/read/28741172/glass-ionomer-cement-inhibits-secondary-caries-in-an-in-vitro-biofilm-model
#13
Norbert Krämer, Miriam Schmidt, Susanne Lücker, Eugen Domann, Roland Frankenberger
OBJECTIVES: The objective of this study was to investigate the effect of different glass ionomer cements on secondary caries inhibition in a fully automated in vitro biofilm model. MATERIALS AND METHODS: One hundred and twenty-four extracted third molars received class V cavities and were filled with one conventional (Ketac Molar/KM), and two resin-modified glass ionomer cements (Photac Fil/PF, Ketac N100/KN, 3M Espe). A bonded resin composite (Single Bond Plus/Filtek Supreme XTE) served as control...
July 24, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28735355/a-systematic-review-of-dental-disease-management-in-cancer-patients
#14
Catherine H L Hong, Shijia Hu, Thijs Haverman, Monique Stokman, Joel J Napeñas, Jacolien Bos-den Braber, Erich Gerber, Margot Geuke, Emmanouil Vardas, Tuomas Waltimo, Siri Beier Jensen, Deborah P Saunders
INTRODUCTION: This systematic review aims to update on the prevalence of odontogenic-related infections and the efficacy of dental strategies in preventing dental-related complications in cancer patients since the 2010 systematic review. REVIEW METHOD: A literature search was conducted in the databases MEDLINE/PubMed and EMBASE for articles published between 1 January 2009 and 30 June 2016. Each study was assessed by 2 reviewers and the body of evidence for each intervention was assigned an evidence level...
July 22, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28722671/can-polysaccharide-k-improve-therapeutic-efficacy-and-safety-in-gastrointestinal-cancer-a-systematic-review-and-network-meta-analysis
#15
Yan Ma, Xiaofen Wu, Jingwen Yu, Jinyan Zhu, Xia Pen, Xianjun Meng
OBJECTIVE: To assess the comparative efficacy and safety of polysaccharide K (PSK), with or without chemotherapy, for patients with gastrointestinal cancer (GIC) through a systematic review and network meta-analysis. MATERIALS AND METHODS: We performed a network meta-analysis to identify evidence from randomized controlled trials. We searched PubMed, Embase and the Cochrane Library for publications up to May 2017. The prespecified primary efficacy outcomes were 1-7 year overall survival (OS), while the secondary efficacy outcomes were 1-7 year disease-free survival (DFS); we performed subgroup analyses and meta-regressions according to the cancer type (colorectal, esophagus and gastric cancer) and treatment arms (with or without chemotherapy)...
July 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/28722001/enamel-color-changes-following-orthodontic-treatment
#16
REVIEW
Akshaya Pandian, Sukanya Ranganathan, Sridevi Padmanabhan
OBJECTIVE: To evaluate and compare the effect of various orthodontic bonding systems and clean up procedures on quantitative enamel colour change. MATERIALS AND METHODS: A literature search was done to identify the studies that assessed the quantitative enamel colour change associated with the various bonding systems and cleanup procedures. Electronic database (Pub Med, Cochrane and Google Scholar) were searched. First stage screening was performed and the abstracts were selected according to the initial selection criteria...
May 2017: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/28709651/modeling-and-analysis-of-fractional-order-dc-dc-converter
#17
Ahmed G Radwan, Ahmed A Emira, Amr M AbdelAty, Ahmed T Azar
Due to the non-idealities of commercial inductors, the demand for a better model that accurately describe their dynamic response is elevated. So, the fractional order models of Buck, Boost and Buck-Boost DC-DC converters are presented in this paper. The detailed analysis is made for the two most common modes of converter operation: Continuous Conduction Mode (CCM) and Discontinuous Conduction Mode (DCM). Closed form time domain expressions are derived for inductor currents, voltage gain, average current, conduction time and power efficiency where the effect of the fractional order inductor is found to be strongly present...
July 11, 2017: ISA Transactions
https://www.readbyqxmd.com/read/28701639/synthesized-mesoporous-silica-and-calcium-aluminate-cement-fillers-increased-the-fluoride-recharge-and-lactic-acid-neutralizing-ability-of-a-resin-based-pit-and-fissure-sealant
#18
Atikom Surintanasarn, Krisana Siralertmukul, Niyom Thamrongananskul
This study evaluated the effect of different types of filler in a resin-based pit and fissure sealant on fluoride release, recharge, and lactic acid neutralization. Resin-based sealant was incorporated with 5% w/w of the following fillers: calcium aluminate cement (CAC), synthesized mesoporous silica (SI), a CAC and SI mixture (CAC+SI), glass-ionomer powder (GIC), and acetic acid-treated GIC (GICA). Sealant without filler served as control. The samples were immersed in deionized water or a lactic acid solution and the concentration of fluoride in the water, before and after fluoride recharge, and the lactic acid pH change, respectively, were determined...
July 12, 2017: Dental Materials Journal
https://www.readbyqxmd.com/read/28666274/genetic-polymorphisms-in-human-udp-glucuronosyltransferases-1a7-and-the-risk-of-gastrointestinal-carcinomas-a-systematic-review-and-network-meta-analysis
#19
Yingshi Zhang, Jun Hou, Fan Feng, Dandan Li, Qiyu Jiang, Xiaojuan Li, Qingchun Zhao, Bo-An Li
OBJECTIVE: To identify the association between gastrointestinal carcinomas (GIC) risk and UDP-glucuronosyltransferases (UGTs) 1A7 polymorphisms through a systematic review and network meta-analysis. RESULTS: Seventeen studies were eligible, which included 7738 patients and 18 analyses. First, it was found that compared with non-cancer participants, UGT1A7*1 were significantly decreased in cancer patient groups, especially in hepatocellular carcinoma, colorectal carcinoma, and Asian population groups; UGT1A7*2 was significantly increased in hepatocellular carcinoma and Asian population groups; and UGT1A7*3 was significantly increased in hepatocellular carcinoma, colorectal carcinoma, Caucasian, and Asian population groups...
June 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28659432/a-novel-theranostic-strategy-for-mmp-14-expressing-glioblastomas-impacts-survival
#20
Suchismita Mohanty, Zixin Chen, Kai Li, Goreti Ribeiro Morais, Jessica Klockow, Ketan Yerneni, Laura Pisani, Frederick T Chin, Siddhartha Mitra, Samuel Cheshier, Edwin Chang, Sanjiv Sam Gambhir, Jianghong Rao, Paul M Loadman, Robert A Falconer, Heike E Daldrup-Link
Glioblastoma (GBM) has a dismal prognosis. Evidence from preclinical tumor models and human trials indicates the role of GBM initiating cells (GIC) in GBM drug resistance. Here, we propose a new treatment option with tumor enzyme-activatable, combined therapeutic and diagnostic (theranostic) nanoparticles, which caused specific toxicity against GBM tumor cells and GICs. The theranostic cross-linked iron oxide nanoparticles (CLIO) were conjugated to a highly potent vascular disrupting agent (ICT) and secured with a matrix-metalloproteinase (MMP-14) cleavable peptide...
June 28, 2017: Molecular Cancer Therapeutics
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