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Stephanie Lemos Martins Sicuro, Marilisa Carneiro Leão Gabardo, Carla Castiglia Gonzaga, Nathaly Dias Morais, Flares Baratto-Filho, Gisele Maria Correr Nolasco, Denise Piotto Leonardi
INTRODUCTION: Different materials have been used for intervening in root perforations. These materials are often in contact with resin cements used for cementation of intraradicular retainers. The aim of this study was to evaluate the bond strength of self-adhesive resin cement to different materials used to treat root perforations (mineral trioxide aggregate [MTA], Portland cement [PORT], and glass ionomer cement [GIC]). METHODS: Four discs (10 × 1 mm) of each material (the MTA, PORT, and GIC groups) were embedded into polyvinyl chloride tubes using acrylic resin, ground, and polished until a flat surface was exposed...
October 18, 2016: Journal of Endodontics
Noha Samir Kabil, Amira Saad Badran, Mariem Osama Wassel
BACKGROUND: Antibacterial restorations can increase the success rate of minimum invasive dentistry especially in young permanent molars with deep carious lesions as an attempt to preserve maximum dental structure and avoid pulp exposure. Further research is warranted to evaluate different antibacterial agents. OBJECTIVES: This study aimed to evaluate the efficacy of adding chlorhexidine gluconate (CHX) or aqueous miswak (Salvadora persica) extract on the clinical performance and in vivo antibacterial activity of conventional anhydrous glass ionomer cement (GIC)...
October 21, 2016: International Journal of Paediatric Dentistry
Andrej M Kielbassa, Georg Glockner, Michael Wolgin, Karl Glockner
BACKGROUND: With the Minamata Convention the use of mercury will be phased down, and this undoubtedly will have an effect on dental treatment regimens and economic resources. Composite resin restorations are considered viable alternatives to amalgam fillings; however, these will not be covered completely by health insurance systems in many countries. Recently, a high-viscosity glass-ionomer cement (hvGIC) processed with a resinous coating (RC) has been introduced, and has been marketed as a restorative material in load-bearing Class I cavities (and in Class II cavities with limited size), thus serving as a possible alternative to amalgam fillings...
2016: Quintessence International
L Arendt-Nielsen, G-L Jiang, R DeGryse, C C Turkel
OBJECTIVES: OnabotulinumtoxinA (onabotA) attenuates peripheral nociceptive transduction and consequently neuronal firing. The aim of this mechanistic study was to evaluate the effect of intra-articular (IA) onabotA in patients with painful knee osteoarthritis (OA). METHOD: We conducted a double-blind, randomized, placebo-controlled, 12-week trial using a single ultrasound-guided IA injection of onabotA (200 U). Patients (N = 121) were randomized to receive onabotA (n = 61) or placebo (n = 60)...
October 13, 2016: Scandinavian Journal of Rheumatology
Maryam Moshaverinia, Ali Borzabadi-Farahani, Abdi Sameni, Alireza Moshaverinia, Sahar Ansari
Present study evaluated effects of addition of Nanoparticles fluorapatite (Nano-FA) on microhardness and fluoride release of a Glass Ionomer Cement (GIC, Fuji IX GP Fast). Forty-eight specimens prepared, divided equally into 4 groups (2 with Nano-FA); after 24 h and one week Vickers microhardness (HV) was measured. Nano-FA specimens were made from addition of nano-FA to Fuji IX powder (glass powder/Nano-FA ratio=20:1 wt/wt, 3.6:1 P/L ratio). At 24 h, mean (95% CI) HV for GIC and Nano-FA GIC were 40.59 (39.51-41...
2016: Dental Materials Journal
Hatice Yagmurdur, Figen Leblebici
BACKGROUND AND OBJECTIVES: This study's main aim was to observe the effects of a fibre-enriched nutrition solution on requisite feeding volume, which is directly proportional to energy intake in mechanically ventilated patients with enteral nutrition. METHODS AND STUDY DESIGN: Some 120 patients who required mechanical ventilation and enteral nutrition with a nasogastric tube were studied. Upon ICU admission, the patient's age, gender, weight, height, comorbidities, diagnosis and APACHE II score were recorded...
December 2016: Asia Pacific Journal of Clinical Nutrition
Sanja Jurišić, Gordan Jurišić, Hrvoje Jurić
AIM: The objective of present study was to examine influence of adhesives and methods of enamel pretreatment on the shear bond strength (SBS) of orthodontic brackets. The adhesives used were resin-reinforced glass ionomer cements-GIC (Fuji Ortho LC) and composite resin (Transbond XT). MATERIAL AND METHODS: The experimental sample consisted of 80 extracted human first premolars. The sample was divided into four equal groups, and the metal brackets were bonded with different enamel pretreatments by using two adhesives: group A-10% polyacrylic acid; Fuji Ortho LC, group B-37% phosphoric acid; Fuji Ortho LC, group C-self etching primer; Transbond XT, group D-37% phosphoric acid, primer; Transbond XT...
December 2015: Acta Stomatologica Croatica
T De Caluwé, C W J Vercruysse, H A Declercq, D Schaubroeck, R M H Verbeeck, L C Martens
OBJECTIVE: Bioactive glasses (BAG) form, in contrast to formerly used implant materials, a stable bond with tissues, especially bone, when implanted. Nowadays BAGs are often mixed with a cement/composite that hardens in situ to broaden its applications in dentistry or orthopedics. The bioactivity and biocompatibility of possible BAG candidates for BAG-cement/composite development were evaluated. METHODS: Two fluoride containing BAGs were tested: a Na(+)-containing (45S5F), based on the first commercial BAG, and a Na(+)-free BAG (CF9), with a higher Ca(2+) and PO4(3-) content...
September 26, 2016: Dental Materials: Official Publication of the Academy of Dental Materials
Babita Niranjan, Nandihalli Devendrappa Shashikiran, Shilpy Singla, Ruchi Thakur, Aashutosh Dubey, Satish Maran
INTRODUCTION: A major objective in restorative dentistry is the control of marginal leakage, which may occur because of dimensional changes or lack of adaptation of restorative material to the cavity preparation. Numerous techniques have been advocated to overcome polymerization shrinkage in composite restorations. AIM AND OBJECTIVES: This study investigated microleakage of three different bases under composite resin in sandwich technique using dye penetration and dentin surface interface using scanning electron microscope (SEM)...
October 2016: Journal of the Indian Society of Pedodontics and Preventive Dentistry
Hanan Alzraikat, Nessrin A Taha, Deema Qasrawi, Michael F Burrow
The shear bond strength (SBS) of TheraCal LC to resin composite was evaluated in comparison to Mineral trioxide aggregate (ProRoot MTA) and conventional glass ionomer cement (GIC) using two adhesive systems. A hole was prepared in 90 acrylic blocks (6 mm diameter, 2 mm deep) then filled with TheraCal LC, MTA or Fuji IX (n=30/group). Each group was bonded with either an etch and rinse or 1-step self-etch adhesive. Filtek Z250 composite was bonded to each capping material. Bond strength was tested in a universal testing machine, and data were analyzed using 2-way ANOVA and Duncan's Multiple range test (p<0...
September 29, 2016: Dental Materials Journal
Joe Mathew, Byju P Kurian, Biju Philip, Sunil Mohammed, Preetha Menon, Rajan S Raj
INTRODUCTION: Superior adhesive strength in luting agents is of paramount significance in fixed partial denture success. In this in vitro study five cements were tested for retentive qualities, using both lathe-cut and hand-prepared specimens. MATERIALS AND METHODS: A total of 104 freshly extracted tooth specimens were prepared. Seventy of them were lathe-cut and 30 specimens were hand-prepared to simulate clinical conditions. Five different cements were tested, which included a compomer, a composite, a zinc phosphate, and 2 glass-ionomer luting cements...
2016: Journal of Contemporary Dental Practice
Hongxing Ye, Mantao Chen, Fei Cao, Hongguang Huang, Renya Zhan, Xiujue Zheng
BACKGROUND: Glioblastoma is refractory to conventional treatment, which is combined of surgery, chemotherapy and radiotherapy. Recent studies have shown that glioma initiating cells (GICs) contribute to tumorigenesis and radioresistance. Recently, other studies showed that the GICs use the autophagy as the major pathway to survive. Chloroquine, an anti-malarial chemical, is an autophagic inhibitor which blocks autophagosome fusion with lysosome and slows down lysosomal acidification. The aim of this study was to explore the mechanisms of chloroquine on the radiosensitivity of GICs...
2016: BMC Neurology
Fabio Lugoboni, Antonio Mirijello, Chiara Resentera, Lorenzo Zamboni, Marco Faccini, Rebecca Casari, Anthony Cossari, Gessica Musi, Giorgia Bissoli, Antonio Gasbarrini, Gianluca Quaglio, Giovanni Addolorato
OBJECTIVES: To evaluate prevalence and severity of constipation and quality of life (QoL) in a cohort of opioid-addicted patients treated with opioid substitution treatments. RESEARCH DESIGN AND METHODS: Multicenter observational study. A total of 1057 heroin-dependent patients treated with methadone or buprenorphine were enrolled. Constipation was assessed by Wexner Constipation Scoring System, QoL by General Health Questionnaire (GHQ-12). RESULTS: 38...
September 7, 2016: Expert Opinion on Pharmacotherapy
Babita Sangwan, Rahul Rishi, Mukut Seal, Kanav Jain, Pranjali Dutt, Pratim Talukdar
AIMS: The aim of the present study is to compare and assess the fracture resistance of root canal treated teeth with different restorative materials. MATERIALS AND METHODS: The present in vitro study was carried out on seventy-five freshly extracted, noncarious, single-canal human lower-first premolars with similar anatomic characteristics. Teeth were randomly assigned to five groups with 15 teeth being present in each group. Group I is control group (no alteration done), group II is restored with silver amalgam after endodontic therapy, group III is restored with posterior composite after end-odontic therapy, group IV is restored with posterior glass ionomer cement (GIC) after endodontic therapy, and group V is restored with miracle mix after endodontic therapy...
2016: Journal of Contemporary Dental Practice
Elizabeth Harford-Wright, Nicolas Bidère, Julie Gavard
Glioblastoma multiforme (GBM) is a highly aggressive tumour of the central nervous system and is associated with an extremely poor prognosis. Within GBM exists a subpopulation of cells, glioblastoma-initiating cells (GIC), which possess the characteristics of progenitor cells, have the ability to initiate tumour growth and resist to current treatment strategies. We aimed at identifying novel specific inhibitors of GIC expansion through use of a large-scale chemical screen of approved small molecules. Here, we report the identification of the natural compound β-escin as a selective inhibitor of GIC viability...
September 1, 2016: Oncotarget
Stuart G Dashper, Deanne V Catmull, Sze-Wei Liu, Helen Myroforidis, Ilya Zalizniak, Joseph E A Palamara, N Laila Huq, Eric C Reynolds
Glass ionomer cements (GIC) are dental restorative materials that are suitable for modification to help prevent dental plaque (biofilm) formation. The aim of this study was to determine the effects of incorporating casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) into a GIC on the colonisation and establishment of Streptococcus mutans biofilms and the effects of aqueous CPP-ACP on established S mutans biofilms. S. mutans biofilms were either established in flow cells before a single ten min exposure to 1% w/v CPP-ACP treatment or cultured in static wells or flow cells with either GIC or GIC containing 3% w/w CPP-ACP as the substratum...
2016: PloS One
Sudhanshu Saxena, Sonia Tiwari
AIM: The aim of this study was to compare constituents of glass powder, fluoride release, and antimicrobial properties of new atraumatic restorative treatment material with zirconia fillers and conventional glass ionomer cement (GIC) type IX. MATERIALS AND METHODS: Thisin vitro study comparing Zirconomer and Fuji IX was executed in three parts: (1) energy dispersive X-ray microanalysis of glass powders (2) analysis of fluoride release at 1(st), 3(rd), 7(th), 15(th), and 30(th) day, and (3) antimicrobial activity against Streptococcus mutans, Lactobacillus casei, and Candida albicans at 48 hours...
July 2016: Journal of International Society of Preventive & Community Dentistry
Cristina Riccadonna, Céline Yacoub Maroun, Romain Vuillefroy de Silly, Margaux Boehler, Marta Calvo Tardón, Simone Jueliger, Pietro Taverna, Leticia Barba, Eliana Marinari, Serena Pellegatta, Esen Yonca Bassoy, Denis Martinvalet, Pierre-Yves Dietrich, Paul R Walker
Malignant gliomas are aggressive brain tumours with very poor prognosis. The majority of glioma cells are differentiated (glioma-differentiated cells: GDCs), whereas the smaller population (glioma-initiating cells, GICs) is undifferentiated and resistant to conventional therapies. Therefore, to better target this pool of heterogeneous cells, a combination of diverse therapeutic approaches is envisaged. Here we investigated whether the immunosensitising properties of the hypomethylating agent decitabine can be extended to GICs...
2016: PloS One
Estelle Willems, Arnaud Lombard, Matthias Dedobbeleer, Nicolas Goffart, Bernard Rogister
The main obstacle for the cure of glioblastoma (GBM) is systematic tumor recurrence after treatment. More than 90 % of GBM tumors are indeed recurrent within 5 years after diagnosis and treatment. We urgently need new therapies to specifically address these deadly relapses. A major advance in the understanding of GBM recurrence is the identification of GBM-Initiating Cells (GIC), characterized by their abilities for self-renewal, multilineage differentiation, and proliferation. It appears that these features of GIC could be modulated by the mitotic kinase Aurora A (AurA)...
August 29, 2016: Targeted Oncology
L S Türkün, Ö Kanik
OBJECTIVE: The aim of this study was to evaluate the long-term clinical performance of two encapsulated glass ionomer cements (GICs) (EquiaFil and Riva SC) covered with two different coatings (Equia Coat and Fuji Varnish) over six years using modified US Public Health Service (USPHS) criteria. METHODS: Fifty-four patients having class I and II restorations/caries were included in the study. A total of 256 restorations were made with EquiaFil and Riva SC. Equia Coat or Fuji Varnish was used randomly on the surface of the restorations...
August 29, 2016: Operative Dentistry
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