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Frank detterbeck

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https://www.readbyqxmd.com/read/27890561/role-of-adjuvant-therapy-for-node-negative-lung-cancer-invading-the-chest-wall
#1
Sarah J Gao, Christopher D Corso, Justin D Blasberg, Frank C Detterbeck, Daniel J Boffa, Roy H Decker, Anthony W Kim
INTRODUCTION: The present study investigated the effect of adjuvant chemotherapy and radiation on survival among patients undergoing chest wall resection for T3N0 non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: Patients with T3N0 NSCLC who underwent chest wall resection were identified in the National Cancer Data Base in 2004 to 2012. The cohort was divided into patients who had received adjuvant chemotherapy, radiation therapy, chemoradiation therapy, or no adjuvant treatment...
October 17, 2016: Clinical Lung Cancer
https://www.readbyqxmd.com/read/27876674/brief-report-a-survey-of-thymic-carcinoma-management-patterns-among-international-thymic-malignancy-interest-group-itmig-physicians-with-consensus-from-the-thymic-carcinoma-working-group
#2
Annemarie Shepherd, Gregory Riely, Frank Detterbeck, Charles B Simone, Usman Ahmad, James Huang, Robert Korst, Arun Rajan, Andreas Rimner
INTRODUCTION: Thymic carcinomas are rare epithelial malignancies with limited data to guide management. METHODS: In order to identify areas of agreement and variability in current clinical practice, a 16-question electronic survey was given to members of the International Thymic Malignancy Interest Group (ITMIG). Areas of controversy were discussed with the Thymic Carcinoma Working Group and consensus was achieved, as described. RESULTS: One hundred ITMIG members responded...
November 19, 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27780786/the-8-th-edition-lung-cancer-stage-classification
#3
REVIEW
Frank C Detterbeck, Daniel J Boffa, Anthony W Kim, Lynn T Tanoue
Stage classification provides a nomenclature about the anatomic extent of a cancer; a consistent language provides the ability to communicate about a specific patient and about cohorts of patients in clinical studies. This paper summarizes the 8(th) edition of lung cancer stage classification, which is the worldwide standard as of January 1, 2017. This revision is based on a large global database, a sophisticated analysis, extensive internal validation as well as multiple assessments confirming generalizability...
October 22, 2016: Chest
https://www.readbyqxmd.com/read/27735079/dataset-for-reporting-of-thymic-epithelial-tumours-recommendations-from-the-international-collaboration-on-cancer-reporting-iccr
#4
Andrew G Nicholson, Frank Detterbeck, Alexander Marx, Anja C Roden, Alberto M Marchevsky, Kiyoshi Mukai, Gang Chen, Mirella Marino, Michael A den Bakker, Woo-Ick Yang, Meagan Judge, Lynn Hirschowitz
AIMS: The International Collaboration on Cancer Reporting (ICCR) is a not-for-profit organisation formed by the Royal Colleges of Pathologists of Australasia and the United Kingdom, the College of American Pathologists, the Canadian Association of Pathologists-Association Canadienne des Pathologists (CAP-ACP) in association with the Canadian Partnership Against Cancer (CPAC), and the European Society of Pathology (ESP). Its goal is to produce standardised, internationally agreed, evidence-based datasets for use throughout the world...
October 13, 2016: Histopathology
https://www.readbyqxmd.com/read/27720827/timing-of-surgery-after-neoadjuvant-chemoradiation-in-locally-advanced-non-small-cell-lung-cancer
#5
Sarah J Gao, Christopher D Corso, Elyn H Wang, Justin D Blasberg, Frank C Detterbeck, Daniel J Boffa, Roy H Decker, Anthony W Kim
INTRODUCTION: A subset of patients with potentially resectable clinical stage IIIA non-small cell lung cancer (NSCLC) are managed with trimodality therapy. However, little data exist to guide the timing of surgery after neoadjuvant therapy. This study examined whether the time interval between neoadjuvant chemoradiation (NCRT) and surgical resection impacts overall survival. METHODS: Clinical stage IIIA disease (T1-3 N2) NSCLC patients who underwent neoadjuvant chemoradiation therapy were identified in the National Cancer Data Base (NCDB) between 2004-2012 and categorized based on the interval between chemoradiation and surgery (0 to ≤3, 3 to ≤6, 6 to ≤9, and 9 to ≤12 weeks)...
October 5, 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27687847/hospital-volume-and-outcomes-of-robot-assisted-lobectomies
#6
Lise N Tchouta, Henry S Park, Daniel J Boffa, Justin D Blasberg, Frank C Detterbeck, Anthony W Kim
BACKGROUND: The positive impact of hospital operative volume on outcomes following video-assisted thoracoscopic surgery has been established. The goal of this study was to determine whether or not this volume-outcome relationship translates to robotic-assisted thoracoscopic surgery (RobATS) lobectomy. METHODS: Patients who underwent RobATS lobectomy were identified between 2008 and 2013 in the Healthcare Cost and Utilization Project National Inpatient Sample (HCUP-NIS) database...
September 26, 2016: Chest
https://www.readbyqxmd.com/read/27619638/the-impact-of-chart-on-the-science-of-thymic-malignancies
#7
EDITORIAL
Frank Detterbeck
No abstract text is available yet for this article.
August 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27565401/selective-application-of-lobe-specific-node-dissection
#8
EDITORIAL
Frank C Detterbeck
No abstract text is available yet for this article.
September 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27564681/length-of-stay-from-the-hospital-perspective-practice-of-early-discharge-is-not-associated-with-increased-readmission-risk-after-lung-cancer-surgery
#9
Joshua E Rosen, Michelle C Salazar, Kumar Dharmarajan, Anthony W Kim, Frank C Detterbeck, Daniel J Boffa
OBJECTIVE: To determine if hospitals that routinely discharge patients early after lobectomy have increased readmissions. BACKGROUND: Hospitals are increasingly motivated to reduce length of stay (LOS) after lung cancer surgery, yet it is unclear if a routine of early discharge is associated with increased readmissions. The relationship between hospital discharge practices and readmission rates is therefore of tremendous clinical and financial importance. METHODS: The National Cancer Database was queried for patients undergoing lobectomy for lung cancer from 2004 to 2013 at Commission on Cancer-accredited hospitals, which performed at least 25 lobectomies in a 2-year period...
August 25, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/27458143/the-differential-impact-of-preoperative-comorbidity-on-perioperative-outcomes-following-thoracoscopic-and-open-lobectomies
#10
Oliver K Jawitz, Zuoheng Wang, Daniel J Boffa, Frank C Detterbeck, Justin D Blasberg, Anthony W Kim
OBJECTIVES: Video-assisted thoracoscopic surgery (VATS) lobectomy is quickly becoming the standard of care for many patients with early-stage non-small-cell lung cancer (NSCLC) and benign lung conditions. There is a lack of published data defining the differential impact of preoperative patient comorbidity on outcomes following VATS and OPEN lobectomies, which would be beneficial for procedure selection and clinical decision-making. METHODS: A retrospective analysis of the 2008-2011 Nationwide Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP) database was performed...
July 25, 2016: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/27448762/the-iaslc-lung-cancer-staging-project-methodology-and-validation-used-in-the-development-of-proposals-for-revision-of-the-stage-classification-of-nsclc-in-the-forthcoming-eighth-edition-of-the-tnm-classification-of-lung-cancer
#11
Frank C Detterbeck, Kari Chansky, Patti Groome, Vanessa Bolejack, John Crowley, Lynn Shemanski, Catherine Kennedy, Mark Krasnik, Michael Peake, Ramón Rami-Porta
INTRODUCTION: Stage classification provides a consistent language to describe the anatomic extent of disease and is therefore a critical tool in caring for patients. The Staging and Prognostic Factors Committee of the International Association for the Study of Lung Cancer developed proposals for revision of the classification of lung cancer for the eighth edition of the tumor, node, and metastasis (TNM) classification, which takes effect in 2017. METHODS: An international database of 94,708 patients with lung cancer diagnosed in 1999-2010 was assembled...
September 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27346413/postoperative-radiation-therapy-is-associated-with-longer-overall-survival-in-completely-resected-stage-ii-and-iii-thymoma-an-analysis-of-the-international-thymic-malignancies-interest-group-retrospective-database
#12
Andreas Rimner, Xiaopan Yao, James Huang, Alberto Antonicelli, Usman Ahmad, Robert J Korst, Frank Detterbeck, Daniel R Gomez
OBJECTIVES: The aim of this study was to determine whether postoperative radiation therapy (PORT) is associated with an overall survival (OS) benefit in patients with completely resected Masaoka or Masaoka-Koga stage II and III thymoma. METHODS: All patients with completely resected (R0) stage II or III thymoma were identified in a large database of the International Thymic Malignancy Interest Group. Clinical, pathologic, treatment, and follow-up information were extracted...
October 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27131846/lobectomy-versus-stereotactic-body-radiotherapy-in-healthy-patients-with-stage-i-lung-cancer
#13
Joshua E Rosen, Michelle C Salazar, Zuoheng Wang, James B Yu, Roy H Decker, Anthony W Kim, Frank C Detterbeck, Daniel J Boffa
OBJECTIVES: Stereotactic body radiotherapy is an effective treatment for patients with early-stage non-small cell lung cancer who are not healthy enough to undergo surgery; however, the relative efficacy versus surgery in healthy patients is unknown. The National Cancer Database contains information on patient health and eligibility for surgery, allowing the long-term survival associated with lobectomy and stereotactic body radiotherapy to be compared in healthy patients with clinical stage I disease...
July 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27118714/analyzing-risk-factors-for-morbidity-and-mortality-after-lung-resection-for-lung-cancer-using-the-nsqip-database
#14
Raymond A Jean, Matthew R DeLuzio, Alexander I Kraev, Gongyi Wang, Daniel J Boffa, Frank C Detterbeck, Zuoheng Wang, Anthony W Kim
BACKGROUND: Our goal was to develop a predictive model that identifies how preoperative risk factors and perioperative complications lead to mortality after anatomic pulmonary resections. STUDY DESIGN: This was a retrospective cohort study. The American College of Surgeons NSQIP database was examined for all patients undergoing elective lobectomies for cancer from 2005 through 2012. Fifty-eight pre- and intraoperative risk factors and 13 complications were considered for their impact on perioperative mortality within 30 days of surgery...
June 2016: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/27107787/the-iaslc-lung-cancer-staging-project-proposals-for-coding-t-categories-for-subsolid-nodules-and-assessment-of-tumor-size-in-part-solid-tumors-in-the-forthcoming-eighth-edition-of-the-tnm-classification-of-lung-cancer
#15
REVIEW
William D Travis, Hisao Asamura, Alexander A Bankier, Mary Beth Beasley, Frank Detterbeck, Douglas B Flieder, Jin Mo Goo, Heber MacMahon, David Naidich, Andrew G Nicholson, Charles A Powell, Mathias Prokop, Ramón Rami-Porta, Valerie Rusch, Paul van Schil, Yasushi Yatabe
This article proposes codes for the primary tumor categories of adenocarcinoma in situ (AIS) and minimally invasive adenocarcinoma (MIA) and a uniform way to measure tumor size in part-solid tumors for the eighth edition of the tumor, node, and metastasis classification of lung cancer. In 2011, new entities of AIS, MIA, and lepidic predominant adenocarcinoma were defined, and they were later incorporated into the 2015 World Health Organization classification of lung cancer. To fit these entities into the T component of the staging system, the Tis category is proposed for AIS, with Tis (AIS) specified if it is to be distinguished from squamous cell carcinoma in situ (SCIS), which is to be designated Tis (SCIS)...
August 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27103511/lung-cancer-in-the-very-young-treatment-and-survival-in-the-national-cancer-data-base
#16
Brian N Arnold, Daniel C Thomas, Joshua E Rosen, Michelle C Salazar, Justin D Blasberg, Daniel J Boffa, Frank C Detterbeck, Anthony W Kim
INTRODUCTION: Young patients with lung cancer represent a distinct subset of patients with this disease. The National Cancer Data Base includes patients of all ages and contains detailed staging, treatment, and survival information. The objective of this study was to examine treatment patterns and outcomes in young patients with non-small cell lung cancer (NSCLC). METHODS: The National Cancer Data Base was queried for NSCLC cases from 2003 to 2009. Younger patients were defined as those aged 20 to 46 years...
July 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27073262/a-model-for-predicting-prolonged-length-of-stay-in-patients-undergoing-anatomical-lung-resection-a-national-surgical-quality-improvement-program-nsqip-database-study
#17
Matthew R DeLuzio, Hari B Keshava, Zuoheng Wang, Daniel J Boffa, Frank C Detterbeck, Anthony W Kim
OBJECTIVES: There are currently no studies that have specifically delineated the risk factors for a prolonged length of hospitalization in patients undergoing anatomical lung resection. Knowing these risk factors is important in terms of risk stratification and improving outcomes in the high-risk population. The goal of this study was to identify risk factors associated with a prolonged length of stay (≥14 days) in patients undergoing an anatomical lung resection and to further create a model for predicting the probability of a prolonged length of stay in these patients...
August 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27041452/the-natural-history-of-operable-non-small-cell-lung-cancer-in-the-national-cancer-database
#18
Joshua E Rosen, Hari B Keshava, Xiaopan Yao, Anthony W Kim, Frank C Detterbeck, Daniel J Boffa
BACKGROUND: The survival of untreated non-small cell lung cancer (NSCLC), or the natural history, is an important perspective for patients considering resection for NSCLC. The National Cancer Database (NCDB) allows untreated NSCLC patients who were recommended to undergo surgical resection (ie, "operable") to be identified. The survival of untreated NSCLC patients in the NCDB was studied to determine the natural history of operable NSCLC. METHODS: The NCDB was queried for untreated clinical stage I to IIIA NSCLC patients diagnosed between 2003 and 2009...
May 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27032473/comparison-of-outcomes-between-neuroendocrine-thymic-tumours-and-other-subtypes-of-thymic-carcinomas-a-joint-analysis-of-the-european-society-of-thoracic-surgeons-and-the-international-thymic-malignancy-interest-group
#19
Pier Luigi Filosso, Xiaopan Yao, Enrico Ruffini, Usman Ahmad, Alberto Antonicelli, James Huang, Francesco Guerrera, Federico Venuta, Dirk van Raemdonck, William Travis, Marco Lucchi, Andreas Rimner, Pascal Thomas, Walter Weder, Gaetano Rocco, Frank Detterbeck, Robert Korst
OBJECTIVES: The latest World Health Organization (WHO) histological classification divides thymic epithelial tumours in thymomas and thymic carcinomas (TCs), the latter also including the neuroendocrine thymic tumours (NETTs). NETTs and other TC histotypes have been described to have a significantly lower survival than thymomas, but these two groups of tumours have rarely been compared directly. Using the European Society of Thoracic Surgeons and the International Thymic Malignancy Interest Group datasets, we wanted to study this issue...
October 2016: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/27013407/adjuvant-chemotherapy-for-t3-non-small-cell-lung%C3%A2-cancer-with-additional-tumor-nodules-in-the-same-lobe
#20
Michelle C Salazar, Joshua E Rosen, Brian N Arnold, Daniel C Thomas, Anthony W Kim, Frank C Detterbeck, Justin D Blasberg, Daniel J Boffa
INTRODUCTION: Adjuvant chemotherapy after surgical resection of non-small cell lung cancer is associated with a survival advantage in several staging scenarios. T3 tumors associated with a separate tumor nodule in the same lobe (formerly "satellite nodules") have a significant risk for systemic failure, yet the efficacy of adjuvant chemotherapy in this setting is unknown. The survival of patients with T3 tumors and additional tumor nodules in the same lobe treated with and without postoperative chemotherapy was evaluated to understand the role of adjuvant chemotherapy in this setting...
July 2016: Journal of Thoracic Oncology
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