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https://www.readbyqxmd.com/read/29231323/-analysis-on-mechanism-of-acupuncture-with-three-needles-at-hegu-li-4-and-its-clinical-application
#1
Lizhi Zhang, Nenggui Xu
Inverted horse acupuncture (acupuncture with three needles) at Hegu (LI 4) is different from triple needling, a traditional needling method. Based on DONG's warming yang and tonifying qi by simultaneous acu-puncture at Linggu (Extra) and Dabai (Extra), we palpate points along the large intestine meridian of hand-yangming, and Linggu (Extra), Hegu (LI 4), and Dabai (Extra) are pricked perpendicularly to smooth triple energizer directly. Thus, functions of zangfu organs are holistically adjusted and clinical effect is better...
January 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29230162/a-novel-de-novo-fzd2-mutation-in-a-patient-with-autosomal-dominant-omodysplasia
#2
Seval Türkmen, Malte Spielmann, Nilay Güneş, Alexej Knaus, Ricarda Flöttmann, Stefan Mundlos, Beyhan Tüysüz
We described a heterozygous de novo mutation (G434V) in the frizzled class receptor 2 (FZD2) gene in a patient with distinct facial features including hypertelorism, bilateral cleft lip/palate, short nose with a broad nasal bridge, microretrognathia, and bilateral shortness of the upper limbs, first metacarpal bones, and middle phalanges of the 5th digits. The findings of our patient were compared to an autosomal dominant omodysplasia (OMOD2) family with FZD2 mutation reported in the literature. OMOD2 is a rare skeletal dysplasia and characterized by facial dysmorphism and shortness of the upper extremities and first metacarpal bones...
November 2017: Molecular Syndromology
https://www.readbyqxmd.com/read/29228959/micro-structural-bone-changes-in-early-rheumatoid-arthritis-persist-over-1-year%C3%A2-despite-use-of-disease-modifying-anti-rheumatic-drug-therapy
#3
Lynne M Feehan, Linda L Li, Heather A McKay
BACKGROUND: We used High Resolution - peripheral Quantitative CT (HR-pQCT) imaging to examine peri-articular bone quality in early rheumatoid arthritis (RA) and explore whether bone quality improved over 12-months in individuals receiving care consistent with practice guidelines. METHODS: A 1-year longitudinal cohort study (Baseline and 12-months) evaluating individuals with early RA compared to age/sex-matched peers. Personal demographic and health and lifestyle information were collected for all...
December 11, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29210097/radiography-of-the-distal-extremity-of-the-manus-in-the-donkey-foal-normal-images-and-quantitative-characterization-from-birth-to-2%C3%A2-years-of-age-a-pilot-study
#4
B Van Thielen, I Willekens, A Van der Schicht, P Pestieau, F Verhelle, P Goossens, R Decoster, O Jacqmot, P Delperdange, V Busoni, G De Mol, N Buls, S Provyn, M Kichouh, J de Mey, R Murray
This study describes a radiographic survey of the anatomical development of the distal extremity of the manus in the donkey from 0 to 2 years of age. The right distal limb of 10 donkey foals, born in the spring of 2012, underwent radiographs every month for the first 6 months of age and every 3 months during the following 18 months. Latero-medial radiographs with and without barium marker at the coronary band and dorso-palmar radiographs with both front feet in weight bearing were obtained. The distal physis of the third metacarpal bone and the proximal physis of the proximal phalanx (phalanx proximalis) were closed at the mean age of 18...
December 6, 2017: Anatomia, Histologia, Embryologia
https://www.readbyqxmd.com/read/29202562/intrarticular-injections-of-hyaluronic-acid-for-trapezio-metacarpal-osteoarthritis-a-systematic-review
#5
R Papalia, L A Diaz, G Torre, E Albo, A Tecame, S Sterzi, F Bressi, V Denaro
Osteoarthritis (OA) of the base of the thumb, also known as Trapezio-Metacarpal (TM) OA, is a disabling condition, which mainly affects women and manual workers. When TM OA is not adequately treated, patients develop deformity and loss of function of the thumb. The surgical approach is a widespread strategy to treat this condition, but there is still no consensus on the most effective procedure. Therefore, several conservative strategies are commonly used, such as nonsteroidal anti-inflammatory drugs (NSAIDs) administration, thumb strengthening exercise, splinting, steroid (CS) and hyaluronic acid (HA) intrarticular injections...
December 4, 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29198886/remaining-localsubclinical-joint-inflammation-is-associated-with-deteriorated-metacarpeal-head-bone-microarchitecture-in-rheumatoid-arthritis-patients-low-disease-activity
#6
Shuing Kong, Hervé Locrelle, Adamah Amouzougan, Delphine Denarie, Philippe Collet, Béatrice Pallot Prades, Thierry Thomas, Hubert Marotte
OBJECTIVES: Bone alterations at the subchondral level during rheumatoid arthritis (RA) remain under investigation. It remains unknown whether subchondral bone damage might still occur in RA patients in clinical remission, which could then infer suggesting that even minor subclinical inflammatory changes in the joint can induce local bone loss. METHODS: Thirty-two RA patients treated with biological disease-modifying anti-rheumatic drugs (bDMARDs) with low disease activity since at least 6 months and having erosion on the second or third metacarpeal head were enrolled in this pilot cross-sectional study...
November 30, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/29198076/early-diagnosis-of-osteoporosis-using-radiogrammetry-and-texture-analysis-from-hand-and-wrist-radiographs-in-indian-population
#7
A S Areeckal, N Jayasheelan, J Kamath, S Zawadynski, M Kocher, S David S
We propose an automated low cost tool for early diagnosis of onset of osteoporosis using cortical radiogrammetry and cancellous texture analysis from hand and wrist radiographs. The trained classifier model gives a good performance accuracy in classifying between healthy and low bone mass subjects. INTRODUCTION: We propose a low cost automated diagnostic tool for early diagnosis of reduction in bone mass using cortical radiogrammetry and cancellous texture analysis of hand and wrist radiographs...
December 3, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/29193820/osteology-and-radiological-anatomy-of-the-thoracic-limbs-of-temminck-s-ground-pangolin-smutsia-temminckii
#8
Christine Steyn, John T Soley, Martina R Crole
Temminck's ground pangolin is the only pangolin present in South Africa. It is a myrmecophagous mammal with a bipedal gait. The thoracic limbs are used to break open ant nests, dig for food and expand previously occupied burrows. This study describes the osteology and radiological anatomy of the thoracic limbs of this threatened species. Thoracic limbs from four Temminck's ground pangolins, which succumbed from electrocution or natural causes, were digitally radiographed in situ. The individual bones were then cleaned, described and digitally radiographed...
November 28, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29171977/ultrasonographic-measurements-of-the-metacarpophalangeal-and-talar-cartilage-thicknesses-a-reliability-study-in-healthy-subjects
#9
Şule Şahin Onat, Ayşe Merve Ata, Simão Serrano, Shaw-Gang Shyu, João Constantino, Süha Yalçın, Cengiz Açıkel, Murat Kara, Levent Özçakar
BACKGROUND: Assessment of the joint cartilage using ultrasound (US) imaging is important. OBJECTIVE: Our aim was to investigate the reliabilities of ultrasonographic measurements for talus dome (TCT) and metacarpal cartilage thicknesses (MCT). METHODS: Twenty healthy volunteers were recruited in the study. Every day, five physiatrists measured eight joint cartilage thicknesses. They repeated all the measurements in five consecutive days. RESULTS: Intra-observer intraclass correlation coefficient (ICC) values were "excellent" for all MCTs, except for the 3rd left MCT on the 1st day, 4th left MCT on the 1st day and 4th right MCT on the 3rd day which were "good"...
November 17, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/29169630/kinetic-analysis-of-canine-gait-on-the-effect-of-failure-tendon-repair-and-tendon-graft
#10
Yu-Shiuan Cheng, Ramona Reisdorf, Alyssa Vrieze, Steven L Moran, Peter C Amadio, Kai-Nan An, Chunfeng Zhao
Kinetic analysis of canine gait has been extensively studied, including normal and abnormal gait. However, no research has looked into how flexor tendon injury and further treatment would affect the walking pattern comparing to the uninjured state. Therefore, this study was aimed to utilize a portable pressure walkway system, which has been commonly used for pedobarographic and kinetic analysis in the veterinary field, to examine the effect of a failed tendon repair and tendon graft reconstruction on canine digit kinetics during gait...
November 20, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29159938/proximate-cause-anatomical-correlates-and-obstetrical-implication-of-a-supernumerary-lumbar-vertebra-in-humans
#11
Robert G Tague
OBJECTIVES: Three issues are considered on variation in number of presacral vertebrae (PSV) in humans: (1) sexual difference in number of PSV, (2) inactivation of Hoxd-11 gene as etiology for a supernumerary lumbar vertebra, and (3) anatomical correlates of a supernumerary lumbar vertebra, including lumbar-sacral nearthrosis, and pelvic size. MATERIALS AND METHODS: Sample was 407 skeletonized females and 1,318 males from United States; ages at death were 20 to 49 years...
November 21, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/29159677/not-all-sagittal-band-tears-come-with-extensor-instability-a-case-report-with-radiological-and-operative-correlation
#12
Shuo Li, Jeffrey J Brooks, Jubin Jacob, Ahmadreza Ghasemiesfe, Greg B Marrinan
The sagittal bands are a component of the extensor hood. They serve an important role in stabilizing the extensor tendon by forming a "check-rein" to radial-ulnar translation of the tendon over the metacarpal head, and extending the metacarpophalangeal (MCP) joint by virtue of attaching the extensor tendon to the palmar plate. Injury to the sagittal band is thought to cause extensor instability and subluxation to the contralateral side by disruption of this "check-rein" function, although recent evidence from cadaver studies suggests that ulnar sagittal band tear may be spared of extensor instability...
November 20, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/29151144/parosteal-extra-axial-chordoma-of-the-second-metacarpal-bone-a-case-report-with-literature-review
#13
Shinji Tsukamoto, Daniel Vanel, Alberto Righi, Davide Maria Donati, Costantino Errani
Extra-axial chordoma is a chordoma that occurs in non-axial locations. It is a very rare tumor, with 20 cases reported to date; 14 in bone and six in soft tissue. Of the 14 skeletal extra-axial chordomas, ten were intramedullary and four were intracortical. We report the first case of parosteal extra-axial chordoma arising in the second metacarpal bone, expressing brachyury on immunohistochemical analysis, and describe the pathologic and radiologic findings. We suggest that extra-axial chordoma can occur in parosteal bone lesions or the hand, without features of bone distribution or bone-specific sites...
November 18, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/29150383/the-diagnostic-clinical-value-of-thumb-metacarpal-grind-pressure-shear-flexion-and-extension-tests-for-carpometacarpal-osteoarthritis
#14
Yaron Sela, Jodi Seftchick, William L Wang, Mark E Baratz
STUDY DESIGN: Clinical measurement. INTRODUCTION: Common provocative maneuvers to differentiate thumb carpometacarpal (CMC) osteoarthritis from other sources of pain are the grind, metacarpal (MC) flexion, and MC extension tests. A maneuver known as the pressure-shear test is described here. PURPOSE OF THE STUDY: To compare the diagnostic value of the grind, metacarpal flexion, metacarpal extension, and pressure-shear tests for CMC osteoarthritis of the thumb...
November 14, 2017: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
https://www.readbyqxmd.com/read/29146507/impact-of-osteoarthritis-and-total-joint-arthroplasty-on-the-kinematics-of-the-trapeziometacarpal-joint-a-pilot-study
#15
Priscilla D'Agostino, Benjamin Dourthe, Faes Kerkhof, Evie E Vereecke, Filip Stockmans
PURPOSE: To quantify the effect of osteoarthritis (OA) and total trapeziometacarpal (TMC) joint replacement on thumb kinematics during the primary physiological motions of the thumb. METHODS: We included 4 female patients with stage III TMC OA. A computed tomography-based markerless method was used to quantify the 3-dimensional thumb kinematics in patients before and after TMC joint replacement surgery with the Arpe implant. RESULTS: Trapeziometacarpal OA led to a marked decrease of internal rotation and abduction of the first metacarpal (MC1) during thumb flexion and a decrease of MC1 adduction during thumb adduction...
November 14, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29143334/pk-pd-modeling-of-flunixin-meglumine-in-a-kaolin-induced-inflammation-model-in-piglets
#16
O L Levionnois, T K Fosse, B Ranheim
Flunixin is marketed in several countries for analgesia in adult swine but little is known about its efficacy in piglets. Thirty-two piglets (6-8 days old) were randomized to receive placebo saline (n = 11, group CONTROL) or flunixin meglumine intravenously at 2.2 (n = 11, group MEDIUM) or 4.4 (n = 10, group HIGH) mg/kg, 10 hr after subcutaneous injection of kaolin in the left metacarpal area. A hand-held algometer was used to determine each piglet's mechanical nociceptive threshold (MNT) from both front feet up to 50 hr after treatment (cut-off value of 24...
November 16, 2017: Journal of Veterinary Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29131674/congenital-malformations-resembling-vacterl-association-in-a-golden-retriever
#17
Araceli Gamito-Gómez, Rodrigo Gutierrez-Quintana, Annette Wessmann
A 2 mo old golden retriever presented with malformation of the left thoracic limb and a small circular indentation of the skin in the cranial thoracic spine. Radiographs showed a cleft between the second and fifth metacarpal bones of the left thoracic limb compatible with ectrodactyly and spina bifida affecting T4 and T5 vertebrae. Magnetic resonance imaging of the thoracic spine showed dorsal reposition of the spinal cord and a tract connecting from the dura mater to the skin. No other malformations were detected...
November 13, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29117837/extensor-digitorum-communis-edc-anchor-and-interposition-arthroplasty-for-the-metacarpo-phalangeal-joint-mcpj
#18
Ulrich Mennen
Replacing a destroyed MCPJ has always been a challenge. Few operations have resulted in consistent satisfactory results. Also, anchoring a subluxed EDC tendon from the metacarpal head has produced numerous corrective procedures, again indicating the difficulty to keep the extensor tendon aligned. The EDC anchor and interposition arthroplasty procedure addresses both these challenging problems.
December 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/29114853/the-evolution-of-the-manus-of-early-theropod-dinosaurs-is-characterized-by-high-inter-and-intraspecific-variation
#19
Daniel E Barta, Sterling J Nesbitt, Mark A Norell
The origin of the avian hand, with its reduced and fused carpals and digits, from the five-fingered hands and complex wrists of early dinosaurs represents one of the major transformations of manus morphology among tetrapods. Much attention has been directed to the later part of this transition, from four- to three-fingered taxa. However, earlier anatomical changes may have influenced these later modifications, possibly paving the way for a later frameshift in digit identities. We investigate the five- to four-fingered transition among early dinosaurs, along with changes in carpus morphology...
November 8, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/29108899/kallmann-syndrome-phenotype-and-genotype-of-hypogonadotropic-hypogonadism
#20
M I Stamou, N A Georgopoulos
Isolated Gonadotropin-Releasing Hormone (GnRH) Deficiency (IGD) IGD is a genetically and clinically heterogeneous disorder. Mutations in many different genes are able to explain ~40% of the causes of IGD, with the rest of cases remaining genetically uncharacterized. While most mutations are inherited in X-linked, autosomal dominant, or autosomal recessive pattern, several IGD genes are shown to interact with each other in an oligogenic manner. In addition, while the genes involved in the pathogenesis of IGD act on either neurodevelopmental or neuroendocrine pathways, a subset of genes are involved in both pathways, acting as "overlap genes"...
November 3, 2017: Metabolism: Clinical and Experimental
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