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JOURNAL ARTICLE
B D Aparicio-Huacarpuma, Fermin Fidel Herrera Aragon, Leonardo Villegas-Lelovsky, C M Soncco, D G Pacheco-Salazar, Jorge Andres Guerra, Paulo C De Morais, S W Da Silva, Jose A H Coaquira
In this study, copper thin films were deposited through thermal evaporation, with film thickness controlled by modulating the Z-position. The grain size (< D >) exhibited a power law relationship (< D >∝ ωn ) with n approximately 0.41 for as-fabricated copper films. Resistivity ranged from 3.3 to 4.6 µΩ·cm, aligning with expectations for crystallites sized between 20 and 26 nm. Cuprite (Cu2 O) thin films were produced via thermal annealing, revealing crystallite sizes from ∼9 nm to ∼24 nm as film thickness increased...
May 6, 2024: Nanotechnology
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JOURNAL ARTICLE
Winston Dunn, Yanming Li, Ashwani K Singal, Douglas A Simonetto, Luis A Díaz, Francisco Idalsoaga, Gustavo Ayares, Jorge Arnold, María Ayala-Valverde, Diego Perez, Jaime Gomez, Rodrigo Escarate, Eduardo Fuentes-López, Carolina Ramirez-Cadiz, Dalia Morales-Arraez, Wei Zhang, Steve Qian, Joseph C Ahn, Seth Buryska, Heer Mehta, Nicholas Dunn, Muhammad Waleed, Horia Stefanescu, Andreea Bumbu, Adelina Horhat, Bashar Attar, Rohit Agrawal, Joaquín Cabezas, Victor Echavaría, Berta Cuyàs, Maria Poca, German Soriano, Shiv K Sarin, Rakhi Maiwall, Prasun K Jalal, Fátima Higuera-de-la-Tijera, Anand V Kulkarni, P Nagaraja Rao, Patricia Guerra-Salazar, Lubomir Skladaný, Natália Kubánek, Veronica Prado, Ana Clemente-Sanchez, Diego Rincon, Tehseen Haider, Kristina R Chacko, Gustavo A Romero, Florencia D Pollarsky, Juan C Restrepo, Luis G Toro, Pamela Yaquich, Manuel Mendizabal, Maria L Garrido, Sebastián Marciano, Melisa Dirchwolf, Victor Vargas, César Jiménez, David Hudson, Guadalupe García-Tsao, Guillermo Ortiz, Juan G Abraldes, Patrick S Kamath, Marco Arrese, Vijay H Shah, Ramon Bataller, Juan P Arab
BACKGROUND AIMS: Alcohol-associated hepatitis (AH) poses significant short-term mortality. Existing prognostic models lack precision for 90-day mortality. Utilizing artificial intelligence (AI) in a global cohort, we sought to derive and validate an enhanced prognostic model. APPROACH AND RESULTS: The Global AlcHep initiative, a retrospective study across 23 centers in 12 countries, enrolled AH patients per NIAAA criteria. Centers were partitioned into derivation (11 centers, 860 patients) and validation cohorts (12 centers, 859 patients)...
April 12, 2024: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
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JOURNAL ARTICLE
Adriana Pedreanez, Jorge Robalino, Diego Tene, Patricio Salazar
Advanced glycation end products (AGEs) are a diverse group of compounds that are formed as a result of the non-enzymatic reaction between a reducing sugar such as glucose and the free NH2 groups of an amino acid in a protein or other biomolecule. The chemical reaction, by which these products are generated, is known as the Maillard reaction and occurs as a part of the body's normal metabolism. Such a reaction is enhanced during diabetes due to hyperglycemia, but it can also occur during the preparation, processing, and preservation of certain foods...
January 1, 2024: Endocrine Regulations
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JOURNAL ARTICLE
Pablo Luna-Villouta, Luis Valenzuela Contreras, Cristian Martínez Salazar, Jorge Flández Valderrama, Carlos Matus-Castillo, Carol Flores-Rivera, Marcelo Paredes-Arias, Rodrigo Vargas-Vitoria
Junior tennis players travel a lot to play tennis tournaments; this causes them to spend a lot of time away from their homes and disrupts their training, which could reduce their performance and increase the risk of injury. The purpose of this study was to analyze the changes in physical performance and body composition after a six-week international tour in young Chilean female tennis players. Thirty young female tennis players (15.4 ± 0.6) participated in this study. Body weight, skinfolds, and perimeters were measured...
March 11, 2024: Sports
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JOURNAL ARTICLE
Taylor S Koerner, Thomas Cunningham, Mayme E Marshall, Lauren S Talley, Megan Childress, Rami M Kharouf, Wen Li, Jorge D Salazar, Antonio F Corno
BACKGROUND: Asymmetry of the aortic valve leaflets has been known since Leonardo Da Vinci, but the relationship between size and shape and origin of the coronary arteries has never been examined. Our aim was to evaluate this anatomy in a population of pediatric patients using a cross-sectional study design. METHODS: Consecutive pediatric patients with trans-esophageal echocardiography (TEE), with or without trans-thoracic echocardiography (TTE), were included in our study...
December 26, 2023: Translational Pediatrics
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JOURNAL ARTICLE
Iván Darío Velez, Alexander Uribe, Jovany Barajas, Sandra Uribe, Sandra Ángel, Juan David Suaza-Vasco, Maria Camila Mejia Torres, María Patricia Arbeláez, Eduardo Santacruz-Sanmartin, Lorena Duque, Luis Martínez, Tania Posada, Ana Cristina Patiño, Sandra Milena Gonzalez, Ana Lucía Velez, Jennifer Ramírez, Marlene Salazar, Sandra Gómez, Jorge E Osorio, Inaki Iturbe-Ormaetxe, Yi Dong, Frederico C Muzzi, Edwige Rances, Petrina H Johnson, Ruth Smithyman, Bruno Col, Benjamin R Green, Tibor Frossard, Jack Brown-Kenyon, D Albert Joubert, Nelson Grisales, Scott A Ritchie, Jai A Denton, Jeremie R L Gilles, Katherine L Anders, Simon C Kutcher, Peter A Ryan, Scott L O'Neill
BACKGROUND: The wMel strain of Wolbachia has been successfully introduced into Aedes aegypti mosquitoes and has been shown to reduce the transmission of dengue and other Aedes-borne viruses. Here we report the entomological results from phased, large-scale releases of Wolbachia infected Ae. aegypti mosquitoes throughout three contiguous cities located in the Aburrá Valley, Colombia. METHODOLOGY/PRINCIPAL FINDINGS: Local wMel Wolbachia-infected Ae. aegypti mosquitoes were generated and then released in an initial release pilot area in 2015-2016, which resulted in the establishment of Wolbachia in the local mosquito populations...
November 2023: PLoS Neglected Tropical Diseases
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JOURNAL ARTICLE
Andrea Perinot, Francesca Scuratti, Alberto D Scaccabarozzi, Karolina Tran, Jorge Mario Salazar-Rios, Maria Antonietta Loi, Giovanni Salvatore, Simone Fabiano, Mario Caironi
The integration of organic electronic circuits into real-life applications compels the fulfillment of a range of requirements, among which the ideal operation at a low voltage with reduced power consumption is paramount. Moreover, these performance factors should be achieved via solution-based fabrication schemes in order to comply with the promise of cost- and energy-efficient manufacturing offered by an organic, printed electronic technology. Here, we propose a solution-based route for the fabrication of low-voltage organic transistors, encompassing ideal device operation at voltages below 5 V and exhibiting n-type unipolarization...
November 21, 2023: ACS Applied Materials & Interfaces
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Emma Karina Martínez-Cárdenas, Adrian Torres-Parlange, Jorge Sotelo-Carbajal, René Edivaldo Hernández-Zamora, Arnold García-Ledezma, Quitzia Libertad Torres-Salazar
INTRODUCTION AND IMPORTANCE: The thoracic outlet syndrome is characterized by compression of the brachial plexus or subclavian vessels due to anatomical alterations of the thoracic cavity. Vascular presentation is rare and includes thromboembolism and edema in the upper limb, and the diagnosis is often elusive due to its rarity. In this case, we describe a vascular thoracic outlet syndrome presentation whose diagnosis through angiography was achieved after a mechanical thrombectomy. CASE PRESENTATION: We report a 43-year-old female patient with pain in the right upper limb, accompanied by edema and mild violet discoloration, without risk factors for hypercoagulability, with D-dimer levels within normal values...
December 2023: International Journal of Surgery Case Reports
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JOURNAL ARTICLE
Kyle G Mitchell, Julija Dobrila, Blaz Podgorsek, Christopher Greenleaf, Peter Chen, Jorge D Salazar, Damien J LaPar
Aortic arch obstruction is often present with complex concomitant congenital heart defects (CHDs). The use of nonvalved femoral vein homograft (FVH) to reconstruct the aortic arch has distinct surgical advantages, including simplified reconstruction. We present an intraoperative video of a Yasui procedure utilizing FVH for aortic reconstruction in a 12-day-old (2.2 kg) neonate with right ventricular outflow tract obstruction, malalignment ventricular septal defect, aortic valve atresia, aortic arch hypoplasia, atrial septal defect, and ductal dependent systemic circulation...
September 11, 2023: World Journal for Pediatric & Congenital Heart Surgery
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REVIEW
Juan Sebastian Marín, Enrique A Mazenett-Granados, Juan Carlos Salazar-Uribe, Mauricio Sarmiento, John Fredy Suárez, Manuel Rojas, Marlon Munera, Rosalbina Pérez, Claudia Morales, Jorge I Dominguez, Juan-Manuel Anaya
An increase in the incidence of inflammatory arthritis after COVID-19 has been reported. Since many diseases exhibit population-specific causal effect sizes, we aimed to evaluate the incidence trends of inflammatory arthritis, including rheumatoid arthritis (RA), after COVID-19 in a large admixed Colombian population. Data analysis for this retrospective, population-based cohort study was carried out using the COOSALUD EPS registry. The following codes were selected for analyses: M059, seropositive RA, M069, unspecified RA, M060 seronegative RA, and other RA-related diagnoses: M064, M139, M068, M058, M130 and M053...
October 2023: Autoimmunity Reviews
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JOURNAL ARTICLE
Luis Antonio Díaz, Eduardo Fuentes-López, Gustavo Ayares, Francisco Idalsoaga, Jorge Arnold, María Ayala Valverde, Diego Perez, Jaime Gómez, Rodrigo Escarate, Alejandro Villalón, Carolina A Ramírez, Maria Hernandez-Tejero, Wei Zhang, Steve Qian, Douglas A Simonetto, Joseph C Ahn, Seth Buryska, Winston Dunn, Heer Mehta, Rohit Agrawal, Joaquín Cabezas, Inés García-Carrera, Berta Cuyàs, Maria Poca, German Soriano, Shiv K Sarin, Rakhi Maiwall, Prasun K Jalal, Saba Abdulsada, Fátima Higuera-de-la-Tijera, Anand V Kulkarni, P Nagaraja Rao, Patricia Guerra Salazar, Lubomir Skladaný, Natália Bystrianska, Ana Clemente-Sanchez, Clara Villaseca-Gómez, Tehseen Haider, Kristina R Chacko, Gustavo A Romero, Florencia D Pollarsky, Juan Carlos Restrepo, Susana Castro-Sanchez, Luis G Toro, Pamela Yaquich, Manuel Mendizabal, Maria Laura Garrido, Sebastián Marciano, Melisa Dirchwolf, Victor Vargas, César Jiménez, Alexandre Louvet, Guadalupe García-Tsao, Juan Pablo Roblero, Juan G Abraldes, Vijay H Shah, Patrick S Kamath, Marco Arrese, Ashwani K Singal, Ramon Bataller, Juan Pablo Arab
BACKGROUND & AIMS: Model for End-Stage Liver Disease (MELD) score better predicts mortality in alcohol-associated hepatitis (AH) but could underestimate severity in women and malnourished patients. Using a global cohort, we assessed the ability of the MELD 3.0 score to predict short-term mortality in AH. METHODS: This was a retrospective cohort study of patients admitted to hospital with AH from 2009 to 2019. The main outcome was all-cause 30-day mortality. We compared the AUC using DeLong's method and also performed a time-dependent AUC with competing risks analysis...
August 2023: JHEP reports: innovation in hepatology
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JOURNAL ARTICLE
Monica Gandhi, Matthew Hickey, Elizabeth Imbert, Janet Grochowski, Francis Mayorga-Munoz, John D Szumowski, Jon Oskarsson, Mary Shiels, John Sauceda, Jorge Salazar, Samantha Dilworth, Janet Q Nguyen, David V Glidden, Diane V Havlir, Katerina A Christopoulos
BACKGROUND: Intramuscular cabotegravir (CAB) and rilpivirine (RPV) is the only long-acting antiretroviral therapy (LA-ART) regimen approved for people with HIV (PWH). Long-acting ART holds promise for improving outcomes among populations with barriers to adherence but is only approved for PWH who have virologic suppression with use of oral ART before initiating injectables. OBJECTIVE: To examine LA-ART in a population of PWH that includes those with viremia. DESIGN: Observational cohort study...
July 2023: Annals of Internal Medicine
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JOURNAL ARTICLE
Andrea Salazar-García, Sagrario M Montemayor, Jorge Luis Guzmán-Mar, Bertha A Puente-Urbina, Gilberto F Hurtado-López, Laura Hinojosa-Reyes
Rapid synthesis of carbon-based magnetic materials derived from cobalt and iron metal-organic frameworks (MOFs), ZIF-67, and MIL-100(Fe), by microwave-assisted method, followed by carbonization under a N2 atmosphere is described in this study. The carbon-derived MOFs (CDMs) were evaluated for the removal of the emerging pollutants sulfadiazine (SDZ) and flumequine (FLU) used as veterinary drugs. The study aimed to link the adsorption behavior with their surface properties and elemental composition...
June 6, 2023: Environmental Science and Pollution Research International
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JOURNAL ARTICLE
John A Sauceda, Nadra E Lisha, Natasha Ludwig-Barron, Jorge Salazar, Samantha E Dilworth, Mallory O Johnson, Katerina A Christopoulos, Kimberly A Koester, Richard D Moore, Kenneth H Mayer, Rob J Fredericksen, Michael J Mugavero, Torsten B Neilands
We created a brief version of The Index, a validated patient-reported measure that has potential to quickly identify patients at risk for poor retention. We analyzed Index scores from 2406 patients from 2016-17 in a national cohort of patients in HIV care. Index scores predicted poor retention 12-months after administered.
April 5, 2023: Clinical Infectious Diseases
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REVIEW
Antonio F Corno, Tina O Findley, Jorge D Salazar
BACKGROUND AND OBJECTIVE: Key medical and surgical advances have been made in the longitudinal management of patients with "functionally" single ventricle physiology, with the principles of Fontan circulation applied to other complex congenital heart defects. The purpose of this article is to review all of the innovations, starting from fetal life, that led to a change of strategy for single ventricle. METHODS: Our literature review included all full articles published in English language on the Cochrane, MedLine, and Embase with references to "single ventricle" and "univentricular hearts", including the initial history of the treatments for this congenital heart defects as well as the innovations reported within the last decades...
February 28, 2023: Translational Pediatrics
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EDITORIAL
Antonio F Corno, Taylor S Koerner, Jorge D Salazar
No abstract text is available yet for this article.
January 31, 2023: Translational Pediatrics
#17
RANDOMIZED CONTROLLED TRIAL
Arushi Beri, Sweta Kale Pisulkar, Ashutosh D Bagde, Akansha Bansod, Chinmayee Dahihandekar, Balaji Paikrao
BACKGROUND: Facial mutilation and deformities can be caused by cancer, tumours, injuries, infections, and inherited or acquired deformities and has the potential to degrade one's quality of life by interfering with fundamental tasks like communication, breathing, feeding, and aesthetics. Depending on the type of defect, producing maxillofacial prostheses for the rehabilitation of patients with various defects can be challenging and complex. The prosthesis is used to replace missing or damaged parts of the cranium and face, like the nose, auricle, orbit, and surrounding tissues, as well as missing areas of soft and hard tissue, with the primary goal of increasing the patient's quality of life by rehabilitating oral functions such as speech, swallowing, and mastication...
December 27, 2022: Trials
#18
EDITORIAL
Antonio F Corno, Jorge D Salazar
No abstract text is available yet for this article.
November 2022: Translational Pediatrics
#19
EDITORIAL
Antonio F Corno, Taylor S Koerner, Jorge D Salazar
No abstract text is available yet for this article.
December 8, 2022: World Journal of Pediatrics: WJP
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JOURNAL ARTICLE
Noralvis Fleitas-Salazar, Emilio Lamazares, Seidy Pedroso-Santana, Tomás Kappes, Alain Pérez-Alonso, Ángela Hidalgo, Claudia Altamirano, Oliberto Sánchez, Katherina Fernández, Jorge R Toledo
Effective cytokine treatments often require high- and multiple-dose due to the short half-life of these molecules. Here, porcine interferon-alpha (IFNα) is encapsulated in PLGA-chitosan microparticles (IFNα-MPs) to accomplish both slow drug release and drug protection from degradation. A procedure that combines emulsion and spray-drying techniques yielded almost spherical microspheres with an average diameter of 3.00 ± 1.50 μm. SEM, Microtrac, and Z-potential analyses of three IFNα-MP batches showed similar results, indicating the process is reproducible...
October 21, 2022: Biomater Adv
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