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https://www.readbyqxmd.com/read/28231435/impact-of-a-competition-with-two-consecutive-matches-in-a-day-on-physical-performance-in-young-tennis-players
#1
Cesar Gallo-Salazar, Juan Del Coso, David Barbado, Alejandro Lopez-Valenciano, Francisco Javier Santos-Rosa, David Sanz-Rivas, Manuel Moya, Jaime Fernandez-Fernandez
The purpose of this study was to analyze the effects of playing two tennis matches on the same day on physical performance in young tennis players. Twelve well-trained young tennis players took part in a simulated tennis competition consisting of two tennis matches on the same day (morning and afternoon sessions). Before and the day after the competition, physical performance was measured using a battery of countermovement jumps (CMJ), a 10-m sprint, the 5-0-5 agility test, hip, grip and shoulder maximal isometric strength, shoulder range of motion (ROM) and a serve velocity test...
February 23, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28225947/health-workers-cohort-study-methods-and-study-design
#2
Edgar Denova-Gutiérrez, Yvonne N Flores, Katia Gallegos-Carrillo, Paula Ramírez-Palacios, Berenice Rivera-Paredez, Paloma Muñoz-Aguirre, Rafael Velázquez-Cruz, Leticia Torres-Ibarra, Joacim Meneses-León, Pablo Méndez-Hernández, Rubí Hernández-López, Eduardo Salazar-Martínez, Juan O Talavera, Juan Tamayo, Susana Castañón, Ignacio Osuna-Ramírez, Leith León-Maldonado, Mario Flores, Nayeli Macías, Daniela Antúnez, Gerardo Huitrón-Bravo, Jorge Salmerón
Objective: To examine different health outcomes that are associated with specific lifestyle and genetic factors. Materials and methods: From March 2004 to April 2006, a sample of employees from three different health and academic institutions, as well as their family members, were enrolled in the study after providing informed consent. At baseline and follow-up (2010-2013), participants completed a self-administered questionnaire, a physical examination, and provided blood samples...
November 2016: Salud Pública de México
https://www.readbyqxmd.com/read/28225543/cuba-s-aging-and-alzheimer-longitudinal-study
#3
Juan de Jesús Llibre-Rodríguez, Adolfo Valhuerdi-Cepero, Ana M López-Medina, Lisseth Noriega-Fernández, Rutbeskia Porto-Álvarez, Milagros A Guerra-Hernández, Rodolfo I Bosch-Bayard, Tania Zayas-Llerena, Elaine Hernandez-Ulloa, Ana L Rodríguez-Blanco, Enrique Salazar-Pérez, Juan C Llibre-Guerra, Jorge J Llibre-Guerra, Beatriz Marcheco-Teruel
Aging and Alzheimer is a prospective, longitudinal cohort study involving 2944 adults aged ≥65 years from selected areas in Cuba's Havana and Matanzas Provinces. This door-to-door study, which began in 2003, includes periodic assessments of the cohort based on an interview; physical exam; anthropometric measurements; and diagnosis of dementia and its subtypes, other mental disorders, and other chronic non-communicable diseases and their risk factors. Information was gathered on sociodemographic characteristics; disability, dependency and frailty; use of health services; and characteristics of care and caregiver burden...
January 2017: MEDICC Review
https://www.readbyqxmd.com/read/28223768/contact-dermatitis-due-to-lubricant-oils-in-a-brass-musician
#4
Elisa Haroun-Díaz, Rita Rodrigues-Barata, Javier Cuesta-Herranz, Luis Conde-Salazar
No abstract text is available yet for this article.
February 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28222903/modified-mrna-vaccines-protect-against-zika-virus-infection
#5
Justin M Richner, Sunny Himansu, Kimberly A Dowd, Scott L Butler, Vanessa Salazar, Julie M Fox, Justin G Julander, William W Tang, Sujan Shresta, Theodore C Pierson, Giuseppe Ciaramella, Michael S Diamond
The emergence of ZIKV infection has prompted a global effort to develop safe and effective vaccines. We engineered a lipid nanoparticle (LNP) encapsulated modified mRNA vaccine encoding wild-type or variant ZIKV structural genes and tested immunogenicity and protection in mice. Two doses of modified mRNA LNPs encoding prM-E genes that produced virus-like particles resulted in high neutralizing antibody titers (∼1/100,000) that protected against ZIKV infection and conferred sterilizing immunity. To offset a theoretical concern of ZIKV vaccines inducing antibodies that cross-react with the related dengue virus (DENV), we designed modified prM-E RNA encoding mutations destroying the conserved fusion-loop epitope in the E protein...
February 16, 2017: Cell
https://www.readbyqxmd.com/read/28222581/a-comparison-of-the-physiological-demands-imposed-by-competing-in-a-half-marathon-vs-a-marathon
#6
Juan Del Coso, Juan J Salinero, Beatriz Lara, Javier Abián-Vicén, César Gallo-Salazar, Francisco Areces
BACKGROUND: While there is widespread scientific information about the physiological challenges imposed on elite endurance runners during competitions, the information regarding the amateur population is scarce. The aim of this study was to compare the physical and physiological load imposed by competing in a real half-marathon vs a marathon race. METHODS: From a larger group of participants, we selected 22 experienced runners who were matched in pairs (11 marathoners and 11 half-marathoners) for age and anthropometric data...
February 21, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28222119/revised-hammersmith-scale-for-spinal-muscular-atrophy-a-sma-specific-clinical-outcome-assessment-tool
#7
Danielle Ramsey, Mariacristina Scoto, Anna Mayhew, Marion Main, Elena S Mazzone, Jacqueline Montes, Roberto de Sanctis, Sally Dunaway Young, Rachel Salazar, Allan M Glanzman, Amy Pasternak, Janet Quigley, Elizabeth Mirek, Tina Duong, Richard Gee, Matthew Civitello, Gihan Tennekoon, Marika Pane, Maria Carmela Pera, Kate Bushby, John Day, Basil T Darras, Darryl De Vivo, Richard Finkel, Eugenio Mercuri, Francesco Muntoni
Recent translational research developments in Spinal Muscular Atrophy (SMA), outcome measure design and demands from regulatory authorities require that clinical outcome assessments are 'fit for purpose'. An international collaboration (SMA REACH UK, Italian SMA Network and PNCRN USA) undertook an iterative process to address discontinuity in the recorded performance of the Hammersmith Functional Motor Scale Expanded and developed a revised functional scale using Rasch analysis, traditional psychometric techniques and the application of clinical sensibility via expert panels...
2017: PloS One
https://www.readbyqxmd.com/read/28217156/extra-axial-giant-falcine-ependymoma-with-ultra-rapid-growth-in-child-uncommon-entity-with-literature-review
#8
Guru Dutta Satyarthee, Luis Rafael Moscote-Salazar
Ependymoma tends to occur commonly along either on ventricular surfaces of the brain or central canal of the spinal cord. Rarely, ependymoma can develop in the cerebral cortex without attachment to the ventricular structures. However, such occurrence in the purely extra-axial compartment in the falcine region mimicking falcine meningioma is exceedingly rare. The detailed search of primary falcine ependymoma (PEFE) in Medline and PubMed yielded only five isolated case reports. All cases occurred in patient older than 17 years of age; however, our case was a 9-year-old girl...
October 2016: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/28216189/rotavirus-immunization-global-coverage-and-local-barriers-for-implementation
#9
Andrea Lo Vecchio, Ilaria Liguoro, Jorge Amil Dias, James A Berkley, Chris Boey, Mitchell B Cohen, Sylvia Cruchet, Eduardo Salazar-Lindo, Samir Podder, Bhupinder Sandhu, Philip M Sherman, Toshiaki Shimizu, Alfredo Guarino
BACKGROUND: Rotavirus (RV) is a major agent of gastroenteritis and an important cause of child death worldwide. Immunization (RVI) has been available since 2006, and the Federation of International Societies of Gastroenterology Hepatology and Nutrition (FISPGHAN) identified RVI as a top priority for the control of diarrheal illness. A FISPGHAN working group on acute diarrhea aimed at estimating the current RVI coverage worldwide and identifying barriers to implementation at local level...
February 16, 2017: Vaccine
https://www.readbyqxmd.com/read/28215981/vacuolar-control-of-subcellular-cation-distribution-is-a-key-parameter-in-the-adaptation-of-debaryomyces-hansenii-to-high-salt-concentrations
#10
R Herrera, A Salazar, L Ramos-Moreno, C Ruiz-Roldan, J Ramos
Debaryomyces hansenii is a halotolerant and Na(+)-includer yeast that can be isolated from different food and low-water activity products. It has also been defined as a marine-occurring yeast but key aspects for this salt tolerant behavior are far from being understood. Here, we searched for clues helping to elucidate the basis of this ability. Our results on growth, Rb(+) transport, total K(+) and Na(+) content and vacuolar fragmentation are compatible with a yeast species adapted to cope with salt stress...
February 12, 2017: Fungal Genetics and Biology: FG & B
https://www.readbyqxmd.com/read/28215098/the-concerns-of-spanish-patients-with-inflammatory-bowel-disease-as-measured-by-the-rfipc-questionnaire
#11
Edel Berroa de la Rosa, Natalia Mora Cuadrado, Luis Fernández Salazar
BACKGROUND AND OBJECTIVES: Concerns impact the quality of life for patients with inflammatory bowel disease (IBD). We attempted to identify the concerns of IBD patients in our practice, and to assess the applicability of the Rating Form of IBD Patients Concerns (RFIPC) questionnaire to Spanish patients. PATIENTS AND METHODS: One hundred and thirty-one patients seen in our practice filled out the Spanish version of RFIPC. The questionnaire's reliability, validity, and discriminating power were analyzed...
February 20, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28214276/-in-vitro-antifungal-activity-of-azoles-and-amphotericin-b-against-malassezia-furfur-by-the-clsi-m27-a3-microdilution-and-etest-%C3%A2-methods
#12
Juan Camilo Galvis-Marín, María Ximena Rodríguez-Bocanegra, Adriana Del Pilar Pulido-Villamarín, Rubiela Castañeda-Salazar, Adriana Marcela Celis-Ramírez, Melva Yomary Linares-Linares
BACKGROUND: Malassezia furfur is a human skin commensal yeast that can cause skin and opportunistic systemic infections. Given its lipid dependant status, the reference methods established by the Clinical and Laboratory Standards Institute (CLSI) to evaluate antifungal susceptibility in yeasts are not applicable. AIMS: To evaluate the in vitro susceptibility of M. furfur isolates from infections in humans to antifungals of clinical use. METHODS: The susceptibility profile to amphotericin B, itraconazole, ketoconazole and voriconazole of 20 isolates of M...
February 14, 2017: Revista Iberoamericana de Micología
https://www.readbyqxmd.com/read/28211453/mechanism-of-partial-agonism-in-ampa-type-glutamate-receptors
#13
Hector Salazar, Clarissa Eibl, Miriam Chebli, Andrew Plested
Neurotransmitters trigger synaptic currents by activating ligand-gated ion channel receptors. Whereas most neurotransmitters are efficacious agonists, molecules that activate receptors more weakly-partial agonists-also exist. Whether these partial agonists have weak activity because they stabilize less active forms, sustain active states for a lesser fraction of the time or both, remains an open question. Here we describe the crystal structure of an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor (AMPAR) ligand binding domain (LBD) tetramer in complex with the partial agonist 5-fluorowillardiine (FW)...
February 17, 2017: Nature Communications
https://www.readbyqxmd.com/read/28202751/superiority-in-rhesus-macaques-of-targeting-hiv-1-env-gp140-to-cd40-versus-lox-1-in-combination-with-replication-competent-nyvac-kc-for-induction-of-env-specific-antibody-and-t-cell-responses
#14
Gerard Zurawski, Xiaoying Shen, Sandra Zurawski, Georgia D Tomaras, David C Montefiori, Mario Roederer, Guido Ferrari, Christine Lacabaratz, Peter Klucar, Zhiqing Wang, Kathryn E Foulds, Shing-Fen Kao, Xuesong Yu, Alicia Sato, Nicole L Yates, Celia LaBranche, Sherry Stanfield-Oakley, Karen Kibler, Bertram Jacobs, Andres Salazar, Steve Self, Jimmy Fulp, Raphael Gottardo, Lindsey Galmin, Deborah Weiss, Anthony Cristillo, Giuseppe Pantaleo, Yves Levy
We compared the HIV-1-specific immune responses generated by targeting HIV-1 envelope protein (Env gp140) to either CD40 or LOX-1, two endocytic receptors on dendritic cells (DCs), in Rhesus macaques primed with a poxvirus vector (NYVAC-KC) expressing Env gp140. The DC-targeting vaccines, humanized recombinant monoclonal antibodies fused to Env gp140, were administered as a boost with poly ICLC adjuvant either alone or co-administered with the NYVAC-KC vector. All the DC-targeting vaccine administrations with poly ICLC increased the low-level serum anti-Env IgG responses elicited by NYVAC-KC priming significantly more (up to P =0...
February 15, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28194645/expression-of-a-novel-ciliary-protein-iiig9-during-the-differentiation-and-maturation-of-ependymal-cells
#15
M Cifuentes, V Baeza, P M Arrabal, R Visser, J M Grondona, N Saldivia, F Martínez, F Nualart, K Salazar
IIIG9 is the regulatory subunit 32 of protein phosphatase 1 (PPP1R32), a key phosphatase in the regulation of ciliary movement. IIIG9 localization is restricted to cilia in the trachea, fallopian tube, and testicle, suggesting its involvement in the polarization of ciliary epithelium. In the adult brain, IIIG9 mRNA has only been detected in ciliated ependymal cells that cover the ventricular walls. In this work, we prepared a polyclonal antibody against rat IIIG9 and used this antibody to show for the first time the ciliary localization of this protein in adult ependymal cells...
February 13, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28193176/telemonitoring-and-or-self-monitoring-of-blood-pressure-in-hypertension-tasminh4-protocol-for-a-randomised-controlled-trial
#16
Marloes Franssen, Andrew Farmer, Sabrina Grant, Sheila Greenfield, Carl Heneghan, Richard Hobbs, James Hodgkinson, Susan Jowett, Jonathan Mant, Una Martin, Siobhan Milner, Mark Monahan, Emma Ogburn, Rafael Perera-Salazar, Claire Schwartz, Ly-Mee Yu, Richard J McManus
BACKGROUND: Self-monitoring of hypertension is associated with lower systolic blood pressure (SBP). However, evidence for the use of self-monitoring to titrate antihypertensive medication by physicians is equivocal. Furthermore, there is some evidence for the efficacy of telemonitoring in the management of hypertension but it is not clear what this adds over and above self-monitoring. This trial aims to evaluate whether GP led antihypertensive titration using self-monitoring results in lower SBP compared to usual care and whether telemonitoring adds anything to self-monitoring alone...
February 13, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28187651/a-new-species-and-the-shallowest-record-of-i-flabegraviera-i-salazar-vallejo-2012-annelida-flabelligeridae-from-antarctica
#17
Naoto Jimi, Megumu Tsujimoto, Kentaro Watanabe, Keiichi Kakui, Hiroshi Kajihara
A new species of polychaete, Flabegraviera fujiae sp. nov., is described and the first report of F. mundata (Gravier, 1906) from the shallow water around Syowa Station, Antarctica, is presented. Flabegraviera fujiae sp. nov. resembles F. profunda Salazar-Vallejo, 2012 but is discriminated from the latter by having eyes and an exposed cephalic cage. The specimen of F. mundata was collected from a depth of 8 m, providing the shallowest record of this species to date.
January 19, 2017: Zootaxa
https://www.readbyqxmd.com/read/28187630/sternaspidae-annelida-sedentaria-from-vietnam-with-description-of-three-new-species-and-clarification-of-some-morphological-features
#18
Anna E Zhadan, Alexander B Tzetlin, Sergio I Salazar-Vallejo
Five sternaspid species were found near Vietnam shores: Sternaspis britayevi sp. nov., S. costata von Marenzeller, 1879, S. nana sp. nov., S. papillosa sp. nov., and S. spinosa Sluiter 1882. Sternaspis britayevi is described from the shallow water in Vietnam inhabiting soft bottoms; it resembles S. spinosa described from Java and S. thorsoni Sendall & Salazar-Vallejo, 2013 described from the Persian Gulf, but differs in having a medially projected and markedly ribbed fan of the ventro-caudal shield and nearly parallel, distally widened and rounded branchial plates...
January 25, 2017: Zootaxa
https://www.readbyqxmd.com/read/28181308/administration-of-exogenous-hormones-in-ovulatory-and-embryonic-response-in-pelibuey-sheep
#19
A García-Salas, C Cortez-Romero, J Salazar-Ortiz, J Arroyo-Ledezma, V M Ruíz-Vera, H Vaquera-Huerta, J Gallegos-Sánchez
The objective of this study was to evaluate the effect of two sources of commercial porcine pituitary-derived follicle-stimulating hormone (pFSH) and pFSH-porcine Luteinizing Hormone (pLH), including equine chorionic gonadotropin (eCG), in ovulatory and embryonic response in Pelibuey sheep. Twenty-four Pelibuey sheep were used and were assigned randomly to four treatments (n = 6): (T1; 200 mg pFSH-Folltropin(®) ); (T2; 200 mg pFSH + 300 UI eCG-Folligon(®) ); (T3; 250 UI pFSH/pLH-Pluset(®) ) and (T4; 250 UI pFSH/pLH + 300 UI eCG)...
February 8, 2017: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/28180996/predicting-the-potential-role-of-non-human-hosts-in-zika-virus-maintenance
#20
Constantino González-Salazar, Christopher R Stephens, Víctor Sánchez-Cordero
Arboviruses are often maintained in complex cycles involving vertebrates such as mammals or birds and blood-feeding mosquitoes. However, the role of wildlife hosts in their emergence or re-emergence in human populations has received little attention. The recent emergence of Zika virus in America, and previous occurrences of chikungunya and dengue, forces us to confront a potential new disease-emergence phenomenon. Using a spatial data mining framework to identify potential biotic interactions, based on the degree of co-occurrence between different species, we identified those mammal species with the highest potential for establishing mammal-vector interactions, considering as principal vector Aedes aegypti...
February 8, 2017: EcoHealth
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