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Sharon Cox

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https://www.readbyqxmd.com/read/29776861/acceptability-and-functionality-of-the-kettle-strap-an-attempt-to-decrease-kettle-related-burns-in-children
#1
Obakeng Makhubalo, Dorothy Schulman, Heinz Rode, Sharon Cox
BACKGROUND: Extensive hot water burns (HWB) are common at Red Cross War Memorial Children's Hospital (RCWMCH). The majority are caused by kettle scalds. These burn injuries usually affect toddlers living in poor socio-economic circumstances. The majority of these injuries are preventable. AIM: This trial aims to demonstrate the acceptability and functionality of the Kettle Strap as a kettle safety device. The feedback will be used for a public awareness program marketed by the Child Accident Prevention Foundation of Southern Africa and ChildSafe as part of their mandate to reduce kettle related thermal injuries...
May 15, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29771274/identification-of-chronic-obstructive-pulmonary-disease-axes-that-predict-all-cause-mortality-the-copdgene-study
#2
Gregory L Kinney, Stephanie A Santorico, Kendra A Young, Michael H Cho, Peter J Castaldi, Raul San José Estépar, James C Ross, Jennifer G Dy, Barry J Make, Elizabeth A Regan, David A Lynch, Douglas C Everett, Sharon M Lutz, Edwin K Silverman, George R Washko, James D Crapo, John E Hokanson
Chronic Obstructive Pulmonary Disease (COPD) is a syndrome caused by damage to the lungs resulting in decreased pulmonary function and reduced structural integrity. Pulmonary function testing (PFT) is currently used to diagnose and stratify COPD into severity groups and chest computed tomography (CT) imaging is often used to assess structural changes in the lungs. We hypothesized that the combination of PFT and CT phenotypes would provide a more powerful tool for assessing underlying morphologic differences associated with pulmonary function in COPD than PFT alone...
May 16, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29769202/predictors-of-length-of-hospital-stay-after-complete-repair-for-tetralogy-of-fallot-a-prospective-cohort-study
#3
Laura Mercer-Rosa, Okan U Elci, Grace DeCost, Stacy Woyciechowski, Sharon M Edman, Chitra Ravishankar, Christopher E Mascio, Steven M Kawut, Elizabeth Goldmuntz
BACKGROUND: We sought to identify patient and surgical factors associated with time to hospital discharge in patients undergoing complete repair for tetralogy of Fallot. METHODS AND RESULTS: We performed a prospective cohort study of patients with tetralogy of Fallot admitted for complete repair between May 1, 2012 and June 2, 2017 at Children's Hospital of Philadelphia with detailed demographic, clinical, and operative characteristics. The primary outcome was time to hospital discharge...
May 16, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29762230/outcomes-after-infections-in-adolescents-and-young-adults-with-continuous-flow-left-ventricular-assist-devices
#4
Sharon Chen, Ryan S Cantor, Scott Auerbach, Kurt Schumacher, Christopher S Almond, Pirooz Eghtesady, Juan Alejos, Bibhuti B Das, Borah J Hong, Robert Jaquiss, James K Kirklin, Aamir Jeewa
Infections in adult ventricular assist device patients increase subsequent mortality and stroke risk. Less is known about outcomes after infections in younger patients, where diabetes and obesity, risk factors associated with poor outcomes, are less prevalent. The purpose of this study was to examine outcomes after infections in adolescents and young adults with continuous-flow left ventricular assist devices (VAD) bridged to transplant. From Pediatric Interagency Registry for Mechanically Assisted Circulatory Support and Interagency Registry for Mechanical Circulatory Support registries, we identified patients aged 12-29 years with continuous-flow VADs implanted as bridged to transplant from September 2012 to March 2016...
May 11, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29761251/correlation-of-99mtc-sucralfate-scan-and-endoscopic-grading-in-caustic-oesophageal-injury
#5
Babalwa B Nondela, Sharon G Cox, Anita Brink, Alastair J W Millar, Alp Numanoglu
PURPOSE: To determine a correlation between the 99mTc sucralfate scan and the endoscopy findings in children with caustic oesophageal injury. METHODS: This is an observational analytic study of children who had both 99mTc sucralfate scan and endoscopy after caustic substance ingestion at our institution in a period between January 2009 and September 2016. The oesophageal injury was classified into low grade and high grade according to the degree of adhesion on 99mTc sucralfate scan and modification of Zargar endoscopic grading...
May 14, 2018: Pediatric Surgery International
https://www.readbyqxmd.com/read/29757402/adherence-to-healthful-dietary-patterns-is-associated-with-lower-risk-of-hearing-loss-in-women
#6
Sharon G Curhan, Molin Wang, Roland D Eavey, Meir J Stampfer, Gary C Curhan
Background: Specific nutrients have been associated with hearing status, but associations between healthful dietary patterns and risk of hearing loss have not been prospectively evaluated. Objective: We sought to prospectively examine the relations between adherence to the Alternate Mediterranean diet (AMED), the Dietary Approaches to Stop Hypertension (DASH), and the Alternative Healthy Eating Index-2010 (AHEI-2010), and risk of hearing loss. Methods: We conducted a longitudinal cohort study (1991-2013) of 81,818 women in the Nurses' Health Study II, aged 27-44 y at baseline...
May 11, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29754125/projected-real-world-effectiveness-of-using-aggressive-low-density-lipoprotein-cholesterol-targets-among-elderly-statin-users-following-acute-coronary-syndromes-in-canada
#7
David A Alter, Jack V Tu, Maria Koh, Cynthia A Jackevicius, Peter C Austin, Mohammad R Rezai, R Sacha Bhatia, Sharon Johnston, Jacob A Udell, Dennis T Ko
BACKGROUND: The extent to which outcome benefits may be achieved through the implementation of aggressive low-density lipoprotein (LDL) cholesterol targets in real world settings remains unknown, especially among elderly statin users following acute coronary syndromes. METHODS AND RESULTS: A population-based cohort study consisting of 19 544 post-acute coronary syndrome statin-users aged ≥66 years between January 1, 2017 and March 31, 2014 was used to project the number of adverse outcome events (acute myocardial infarction or death from any cause) that could be prevented if all post-acute coronary syndrome elderly statin users were treated to 1 of 2 LDL cholesterol target levels (≤50 and ≤70 mg/dL)...
May 12, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29743156/evaluating-the-impact-of-a-web-based-risk-assessment-system-caresage-and-tailored-interventions-on-health-care-utilization-protocol-for-a-randomized-controlled-trial
#8
Ramya Sita Palacholla, Nils C Fischer, Stephen Agboola, Mariana Nikolova-Simons, Sharon Odametey, Sara Bersche Golas, Jorn Op den Buijs, Linda Schertzer, Joseph Kvedar, Kamal Jethwani
BACKGROUND: Soaring health care costs and a rapidly aging population, with multiple comorbidities, necessitates the development of innovative strategies to deliver high-quality, value-based care. OBJECTIVE: The goal of this study is to evaluate the impact of a risk assessment system (CareSage) and targeted interventions on health care utilization. METHODS: This is a two-arm randomized controlled trial recruiting 370 participants from a pool of high-risk patients receiving care at a home health agency...
May 9, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29728148/an-evidence-based-co-occurring-disorder-intervention-in-va-homeless-programs-outcomes-from-a-hybrid-iii-trial
#9
David A Smelson, Matthew Chinman, Gordon Hannah, Thomas Byrne, Sharon McCarthy
BACKGROUND: Evidence-based treatment for co-occurring disorders is needed within programs that serve homeless Veterans to assist with increasing engagement in care and to prevent future housing loss. A specialized co-occurring disorders treatment engagement intervention called Maintaining Independence and Sobriety Through Systems Integration, Outreach and Networking - Veterans Edition (MISSION-Vet) was implemented within the Housing and Urban Development - Veterans Affairs Supportive Housing (HUD-VASH) Programs with and without an implementation strategy called Getting To Outcomes (GTO)...
May 5, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29689595/potentially-inappropriate-medication-use-in-older-patients-with-breast-and-colorectal-cancer
#10
Meghan S Karuturi, Holly M Holmes, Xiudong Lei, Michael Johnson, Carlos H Barcenas, Scott B Cantor, Gary E Gallick, Robert C Bast, Sharon H Giordano
BACKGROUND: The objective of this study was to determine patient characteristics associated with potentially inappropriate medication (PIM) use and its impact on outcomes for patients with breast or colorectal cancer receiving adjuvant chemotherapy. METHODS: The Surveillance, Epidemiology, and End Results database, linked to Medicare claims, was used. The cohort included patients who were 66 years old or older and were diagnosed with stage II or III breast or colorectal cancer between July 1, 2007, and December 31, 2009...
April 24, 2018: Cancer
https://www.readbyqxmd.com/read/29683846/medication-non-adherence-multi-tablet-regimens-and-food-insecurity-are-key-experiences-in-the-pathway-to-incomplete-hiv-suppression
#11
Celline C Almeida-Brasil, Erica E M Moodie, Taylor Mclinden, Anne-Marie Hamelin, Sharon L Walmsley, Sean B Rourke, Alexander Wong, Marina B Klein, Joseph Cox
OBJECTIVE: To identify potential pathways by which a variety of factors act to lead to unsuppressed viral load. DESIGN: A prospective cohort of HIV-HCV co-infected adults receiving care from 18 HIV clinics across Canada was followed every 6 months between November 2012 and October 2015. Participants with at least two visits while receiving combined antiretroviral treatment (cART) were included. METHODS: A path analysis was conducted on the basis of ordered sequences of multivariate logistic regressions using generalized estimating equations...
April 19, 2018: AIDS
https://www.readbyqxmd.com/read/29674250/aspects-of-alcohol-use-disorder-affecting-social-cognition-as-assessed-using-the-mini-social-and-emotional-assessment-mini-sea
#12
Sharon Cox, Maxime Bertoux, John J D Turner, Antony Moss, Kirsty Locker, Kevin Riggs
BACKGROUND: Alcohol Use Disorder (AUD) is associated with problems with processing complex social scenarios. Little is known about the relationship between distinct AUD-related factors (e.g., years of problematic drinking), aspects of cognitive function and dysfunction in individuals diagnosed with AUD, and the relative impact these may have on social cognition. AIMS: To explore differences in social cognition between a group of participants diagnosed with AUD and controls, using a clinical measure, the Mini Social and Emotional Assessment (mini-SEA)...
April 10, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29672210/prognostic-utility-of-stress-testing-and-cardiac-biomarkers-in-menopausal-women-at-low-to-intermediate-risk-for-coronary-artery-disease-smart-study-5-year-outcome
#13
Sahar S Abdelmoneim, Caroline A Ball, Francesca Mantovani, Mary E Hagen, Susan Eifert-Rain, Susan Wilansky, Ramon Castello, Patricia A Pellikka, Patricia J M Best, Sharon L Mulvagh
BACKGROUND: In women with low to intermediate risk of coronary artery disease (CAD), prognostic detection strategies have been controversial. We present the follow-up data of the SMART trial in peri/postmenopausal women at low to intermediate risk of CAD. OBJECTIVES: To determine the value of contrast stress echocardiography (CSE), stress electrocardiogram (sECG), and serum biomarkers for prediction of cardiovascular events (CE) in peri/postmenopausal women at low to intermediate risk of CAD...
April 19, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29664674/associations-between-neighborhood-walkability-and-incident-and-ongoing-asthma-in-children
#14
Elinor Simons, Sharon D Dell, Rahim Moineddin, Teresa To
RATIONALE: Childhood asthma has shown variable associations with children's physical activity. Neighborhood walkability captures community features that promote walking and is protective against some chronic conditions, such as obesity and diabetes. OBJECTIVES: We evaluated associations between home neighborhood walkability and incident and ongoing childhood asthma. METHODS: This population-based cohort study used prospectively-collected administrative healthcare data for the province of Ontario housed at the Institute for Clinical Evaluative Sciences...
April 17, 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29604042/higher-carbohydrate-intake-is-associated-with-increased-risk-of-all-cause-and-disease-specific-mortality-in-head-and-neck-cancer-patients-results-from-a-prospective-cohort-study
#15
Anna E Arthur, Amy M Goss, Wendy Demark-Wahnefried, Alison M Mondul, Kevin R Fontaine, Yi Tang Chen, William R Carroll, Sharon A Spencer, Laura Q Rogers, Laura S Rozek, Gregory T Wolf, Barbara A Gower
No studies have evaluated associations between carbohydrate intake and head and neck squamous cell carcinoma (HNSCC) prognosis. We prospectively examined associations between pre- and post-treatment carbohydrate intake and recurrence, all-cause mortality, and HNSCC- specific mortality in a cohort of 414 newly diagnosed HNSCC patients. All participants completed pre- and post-treatment Food Frequency Questionnaires (FFQs) and epidemiologic surveys. Recurrence and mortality events were collected annually. Multivariable Cox Proportional Hazards models tested associations between carbohydrate intake (categorized into low, medium and high intake) and time to recurrence and mortality, adjusting for relevant covariates...
March 31, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29596144/the-power-of-gratitude
#16
Sharon Cox
No abstract text is available yet for this article.
April 2018: Nursing Management
https://www.readbyqxmd.com/read/29582539/association-between-atherosclerosis-and-handgrip-strength-in-non-hypertensive-populations-in-india-and-japan
#17
Hirotomo Yamanashi, Bharati Kulkarni, Tansy Edwards, Sanjay Kinra, Jun Koyamatsu, Mako Nagayoshi, Yuji Shimizu, Takahiro Maeda, Sharon E Cox
AIM: Although several risk factors contribute to the development of sarcopenia, whether preclinical atherosclerosis contributes to the risk of sarcopenia is not established. The present cross-sectional study aimed to investigate if there is an association between preclinical atherosclerosis and muscle strength among two ethnic populations. METHODS: Participants included individuals aged ≥40 years and enrolled in the third follow-up examination of the Andhra Pradesh Children and Parents Study, India, and in the baseline assessments of the Nagasaki Islands Study, Japan...
March 26, 2018: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/29565998/two-key-cathepsins-tgcpb-and-tgcpl-are-targeted-by-the-vinyl-sulfone-inhibitor-k11777-in-in-vitro-and-in-vivo-models-of-toxoplasmosis
#18
Juan D Chaparro, Timmy Cheng, Uyen Phuong Tran, Rosa M Andrade, Sara B T Brenner, Grace Hwang, Shara Cohn, Ken Hirata, James H McKerrow, Sharon L Reed
Although toxoplasmosis is one of the most common parasitic infections worldwide, therapeutic options remain limited. Cathepsins, proteases that play key roles in the pathogenesis of toxoplasmosis and many other protozoan infections, are important potential therapeutic targets. Because both TgCPB and TgCPL play a role in T. gondii invasion, we evaluated the efficacy of the potent, irreversible vinyl sulfone inhibitor, K11777 (N-methyl-piperazine-Phe-homoPhe-vinylsulfone-phenyl). The inhibitor's toxicity and pharmacokinetic profile have been well-studied because of its in vitro and in vivo activity against a number of parasites...
2018: PloS One
https://www.readbyqxmd.com/read/29564169/comparison-of-perioperative-chemotherapy-with-adjuvant-chemoradiotherapy-for-resectable-gastric-cancer-findings-from-a-population-based-study
#19
Brice Jabo, Matthew J Selleck, John W Morgan, Sharon S Lum, Khaled A Bahjri, Mayada Aljehani, Carlos A Garberoglio, Mark E Reeves, Jukes P Namm, Naveenraj L Solomon, Fabrizio Luca, Crickett Dyke, Maheswari Senthil
Background: Both perioperative chemotherapy (PC) and adjuvant chemoradiotherapy (CRT) improve survival in resectable gastric cancer; however, these treatments have never been formally compared. Our objective was to evaluate treatment trends and compare survival outcomes for gastric cancer patients treated with surgery and either PC or CRT. Methods: We performed a retrospective population-based cohort study between 2007 through 2013 using California Cancer Registry data...
February 2018: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/29563165/risk-factors-for-mycoplasma-genitalium-endometritis-and-incident-infection-a-secondary-data-analysis-of-the-t-cell-response-against-chlamydia-trac-study
#20
Brandie D Taylor, Xiaojing Zheng, Catherine M O'Connell, Harold C Wiesenfeld, Sharon L Hillier, Toni Darville
OBJECTIVE: Assess risk factors for incident and endometrial Mycoplasma genitalium infection and determine if M. genitalium is associated with histological endometritis, an indicator of pelvic inflammatory disease. METHODS: This study was a secondary data analysis within the T cell Response Against Chlamydia (TRAC) Study, a prospective evaluation of 246 women with or at risk for Chlamydia trachomatis from urban outpatient clinics, who were followed quarterly for 12 months...
March 21, 2018: Sexually Transmitted Infections
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