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https://www.readbyqxmd.com/read/28936049/prevalence-and-risk-factors-of-dry-eye-symptoms-in-a-saudi-arabian-population
#1
Abdulaziz A Alshamrani, Abdulwahab S Almousa, Abdulrahman A Almulhim, Abdullah A Alafaleq, Mohammed B Alosaimi, Abdulrahman M Alqahtani, Ammar M Almulhem, Mohammed A Alshamrani, Ahmad H Alhallafi, Ismail Z Alqahtani, Abdullah A Alshehri
BACKGROUND: The information about dry eye epidemiology in Saudi Arabia is few in literature. PURPOSE: To estimate the prevalence and identify determinants of dry eye symptoms (DES) in Al-Ahsa, Saudi Arabia. METHODS: Using a multi-stage proportionate sampling technique, Saudis of both genders from 6 urban and 4 rural Primary Health Care centers in Al-Ahsa were enrolled. They were interviewed to gather data on sociodemography, symptoms of dry eye, factors potentially related to dry eye, and chronic comorbidities...
April 2017: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/28901394/overexpression-of-atp5b-promotes-cell-proliferation-in-asthma
#2
Jianhong Zuo, Mingsheng Lei, Meilin Wen, Yikun Chen, Zhigang Liu
Asthma is a complicated systemic disease of the airways, which is characterized by variable symptoms, including bronchial hyper‑responsive-ness, inflammation and airflow obstruction. The prevalence of asthma has increased 2‑3‑fold over recent decades in developed countries; however, the molecular mechanism of asthma remains unclear. In the current study, the expression of recombinant protein Dermatophagoides farinaeI (Derf I) was induced by isopropyl β‑D‑1‑thiogalactoside (IPTG) and purified using Ni‑NTA...
August 31, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28901306/bronchial-artery-chemoembolization-combined-with-radioactive-iodine-125-seed-implantation-in-the-treatment-of-advanced-nonsmall-cell-lung-cancer
#3
Yaoyong Chen, Yuwei Li, Yuming Jia, Kaijian Lei, Xinfeng Zhang, Yueyong Cao, Jun Zhu
OBJECTIVE: The aim of this study was to investigate the short-term efficacy and safety of bronchial artery chemoembolization (BACE) combined with radioactive iodine-125 seed implantation in the treatment of nonsmall cell lung cancer (NSCLC). MATERIALS AND METHODS: Sixty-two Stage III-IV NSCLC patients were divided into Groups A and B. Thirty cases were treated with BACE combined with radioactive iodine-125 seed implantation in the Group A and 32 cases were treated with BACE alone in the Group B until disease progression...
2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28900554/primary-epithelioid-angiosarcoma-of-lung-radiologic-and-clinicopathologic-correlation
#4
Fung Him Ng, San Ming Yu, Ophelia Ka Heng Wai, James Chi Sang Chan
Primary pulmonary angiosarcoma is extremely rare. It is often characterized by a clinically indolent course and delayed diagnosis. To date, there have been <20 cases reported. By far, little article correlates the clinical presentation, the imaging findings with the pathology. The authors present a case of middle-aged gentleman with primary pulmonary epithelioid angiosacroma which we initially thought as tuberculosis (TB) infection. A 60-year-old gentleman, with a history of 6 months on and off blood stained sputum, was admitted for an episode of massive hemoptysis...
2017: Journal of Clinical Imaging Science
https://www.readbyqxmd.com/read/28886716/intralobar-pulmonary-sequestration-displayed-as-localized-emphysema-on-computed-tomography-image
#5
Weibo Qi, Junjie Zhao, Guping Shi, Fan Yang
BACKGROUND: Pulmonary sequestration is a relatively rare condition in which a systemic artery supplies blood to an abnormal lung tissue and the normal connection with the bronchial tree is absent. It can be displayed as various signs on the computed tomography image, but emphysema is extremely rare. CASE PRESENTATION: We describe the case of a 35-year-old man with intralobar pulmonary sequestration that appeared as localized emphysema on the computed tomography image...
September 8, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28865478/extracellular-histones-are-clinically-relevant-mediators-in-the-pathogenesis-of-acute-respiratory-distress-syndrome
#6
Xin Lv, Tao Wen, Jiong Song, Dong Xie, Liang Wu, Xuemei Jiang, Ping Jiang, Zongmei Wen
BACKGROUND: Extracellular histones were recently identified as an inflammatory mediator involved in the pathogenesis of various organ injuries. This study aimed to examine extracellular histone levels and their clinical implications in acute respiratory distress syndrome (ARDS) patients and to explore histone-mediated effects through ex-vivo investigations. METHODS: Extracellular histones, cytokine profiles and clinical data from 96 ARDS patients and 30 healthy volunteers were obtained...
September 2, 2017: Respiratory Research
https://www.readbyqxmd.com/read/28855497/a-49-year-old-man-with-subacute-respiratory-failure-and-interstitial-lung-opacities
#7
Anastasiia A Rudkovskaia, Ying-Chun Lo, Virginia Brady, Jose Costa, Wassim H Fares
BACKGROUND Pulmonary arterial hypertension (PAH) results from proliferative vasculopathy involving all layers of the blood vessel. Similar findings may be present in pulmonary hypertension (PH) associated with microscopic tumor embolism, which are thought to be related to the phenomenon of pulmonary tumor thrombotic microangiopathy (PTTM). PTTM is associated with the activation of the coagulation system at the surface of the tumor emboli, resulting in stenosis or occlusion of the vessel. CASE REPORT A 49-year-old man with stage IV gastro-esophageal junction adenocarcinoma presented with complaints of cough and shortness of breath...
August 31, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28851689/the-second-generation-pgi2-analogue-treprostinil-fails-to-chemoprevent-tumors-in-a-murine-lung-adenocarcinoma-model
#8
Lori D Dwyer-Nield, Gregory A Hickey, Micah Friedman, Kevin Choo, Debbie G McArthur, Meredith A Tennis, Melissa L New, Mark Geraci, Robert L Keith
Prostacyclin (prostaglandin I2, PGI2) over-production in FVB/N mice prevents the formation of carcinogen and tobacco smoke induced adenomas, and administration of the oral prostacyclin analog iloprost to wild type mice also prevented carcinogen-induced mouse lung adenoma formation. Former smokers taking oral iloprost showed improved bronchial dysplasia histology compared to placebo. Next generation oral prostacyclin analogues, like treprostinil, were developed for treatment of pulmonary arterial hypertension (PAH)...
August 29, 2017: Cancer Prevention Research
https://www.readbyqxmd.com/read/28828101/diagnosis-of-bronchial-artery-aneurysm-by-computed-tomography-a-case-report
#9
So Hyeon Bak, Heon Han
Bronchial artery aneurysm is a rare vascular abnormality, with an incidence of <1% based on diagnosis by selective bronchial angiography. It is manifested in various forms, ranging from an incidental finding on radiologic examination to life-threatening hemorrhage resulting from aneurysm rupture. We report a case of a 60-year-old man with a mediastinal bronchial artery aneurysm which was incidentally detected on chest computed tomography.
September 2017: Radiology case reports
https://www.readbyqxmd.com/read/28807204/anti-inflammatory-effect-of-dexmedetomidine-combined-with-hypothermia-on-acute-respiratory-distress-syndrome-in-rats
#10
Xianfeng Chen, Lili Li, Juntao Hu, Chi Zhang, Yiping Pan, Diansheng Tian, Zhanhong Tang
BACKGROUND: To investigate the protective effect of combination of dexmedetomidine and hypothermia on lipopolysaccharide (LPS) induced acute respiratory distress syndrome in rats. METHODS: Fifty male Wistar rats were randomly divided into five groups, with 10 rats in each group. The acute respiratory distress syndrome model was reproduced by LPS injected into the right external jugular vein (L group); only saline was injected into the right external jugular vein for control group (C group)...
August 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28806284/is-extracorporeal-cardiopulmonary-resuscitation-practical-in-severe-chest-trauma-a-systematic-review-in-single-center-of-developing-country
#11
Up Huh, Seunghwan Song, Sung Woon Chung, Sang-Pil Kim, Chung Won Lee, Hyo Young Ahn, Miju Bae, Seon Hee Kim
BACKGROUND: We report our experience with extracorporeal cardiopulmonary resuscitation (ECPR) in patients with rupture of heart and major vessels caused by severe chest trauma. METHODS: From April 2015 to May 2016, 10 patients with suspected injuries to the heart and major vessels following focused assessment with sonography in trauma or computed tomography were selected from patients admitted at a level I trauma centre presenting with cardiac tamponade and tension haemothorax due to severe chest trauma...
August 12, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28805775/-the-features-of-diagnosis-and-treatment-of-traumatic-and-non-traumatic-pulmonary-bleeding
#12
Sh N Danielyan, M M Abakumov, E A Tarabrin, L S Kokov, A M Gasanov, A P Wilk, A A Saprin
AIM: To analyze an efficacy of differentiated approach for pulmonary bleeding of different etiology and severity. MATERIAL AND METHODS: The study included 134 cases of pulmonary bleeding for the period 2006-2015 including 53 patients with traumatic and 81 with non-traumatic etiology. Men/women ratio was 2.7:1, mean age was 43 years. Comparative retrospective analysis of X-ray and CT data in diagnosis of bleeding source was performed. Bronchoscopy was used to confirm these data...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28797271/successful-long-term-extracorporeal-membrane-oxygenation-for-invasive-pulmonary-aspergillosis-a-case-report
#13
Hiroyuki Tanaka, Kei Nishiyama, Nobuaki Shime
BACKGROUND: Extracorporeal membrane oxygenation is an established life-saving procedure for severe acute respiratory failure due to various causes. In general, the duration of extracorporeal membrane oxygenation ranges from 1 to 2 weeks, with withdrawal recommended if no improvement is noted. We report a successful case of long-term extracorporeal membrane oxygenation management for respiratory failure due to invasive pulmonary Aspergillus infection. CASE PRESENTATION: A 64-year-old Asian man with no previous underlying medical conditions was transferred to our hospital for fever and dyspnea...
August 11, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28790291/-management-of-fluid-and-nutrition-after-lung-resection-to-prevent-complications
#14
Yukio Sato
It is necessary to understand the biological response and characteristic points for the appropriate management in the fluid and nutrition after lung resection. The characteristic points in the management of lung resection are the decrease of pulmonary vascular bed and the existence of bronchial stump. Due to the decrease of pulmonary vascular bed, the pressures of pulmonary artery and pulmonary microvasculature tend to rise, which could cause pulmonary edema. Therefore, the amount of fluid infusion should be less compared to ordinal management in the management after lung resection, especially pneumonectomy...
July 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28790290/-postoperative-intrathoracic-hemorrhage-perioperative-prevention-and-management
#15
Yoshimasa Maniwa
Postoperative intrathoracic hemorrhage is sometimes diagnosed in the thoracic cavity, while the patient is in the recovery room after undergoing thoracic surgery such as lung resection with thoracotomy or mediastinal surgery with a median sternotomy. The information from the chest tube is important to identify this kind of postoperative complication. When the condition becomes severe, the patient may develop hemorrhagic shock due to hemothorax and re-exploration to assess for bleeding and hemostasis may be required...
July 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28776532/etiology-and-outcome-of-moderate-to-massive-hemoptysis-experience-from-a-tertiary-care-center-of-north-india
#16
Ashish Bhalla, Ashok Kumar Pannu, Vikas Suri
BACKGROUND: The aim of this study was to evaluate the etiology of hemoptysis in patients presenting to emergency department of Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. METHOD: Prospectively 110 patients presenting to the emergency department with history of hemoptysis were screened for a period of one and half years. Out of these, 64 patients having true hemoptysis were enrolled in the study. The patients were clinically evaluated with detailed history...
July 2017: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28748188/arterial-stiffness-in-symptomatic-smokers-with-normal-lung-function
#17
Nicola Scichilone, Antonino Tuttolomondo, Carlo Maida, Alida Benfante, Jessica Peluso, Anna Cirrincione, Valerio Vassallo, Antonio Pinto
Chronic obstructive pulmonary disease (COPD) is associated with cardiovascular morbidity and mortality. Arterial stiffness and endothelial dysfunction index are validated surrogate cardiovascular markers and are increased in subjects with COPD. We tested whether increased arterial stiffness and endothelial dysfunction occur in symptomatic smokers with no evidence of bronchial obstruction. Clinical and lung functional assessments were conducted in smoker subjects with chronic respiratory symptoms and in COPD patients...
July 2017: ERJ Open Research
https://www.readbyqxmd.com/read/28744084/singular-observation-of-a-desirable-change-after-bronchial-artery-embolization-for-hemoptysis-in-intracavitary-aspergilloma
#18
B P K Prasad, Brijesh Ray
Aspergillomas are fungal balls developing in pre-existing lung cavities, which are most commonly secondary to tuberculosis. Aspergillomas can cause hemoptysis due to erosion of the blood vessels in cavity walls, which can often be recurrent, massive, and life-threatening. Bronchial artery embolization is considered to be the treatment of choice for short-term control of hemoptysis, and lobectomy as the definitive treatment for aspergilloma. We present a unique observation in two cases of aspergilloma where the fungal balls disappeared radiologically after bronchial artery embolization performed for massive hemoptysis...
April 2017: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/28734439/coronary-sinus-orifice-atresia-after-the-fontan-completion-unique-repair-technique
#19
Shinya Yokoyama, Takeo Yonekura, Noboru Nishiwaki, Shigeki Taniguchi
We report a successful unroofing of the coronary sinus via a unique technique. Our patient was diagnosed with single ventricle morphology. Pulmonary artery banding and bidirectional cavopulmonary shunt were performed at 1 and 6 months old, respectively. Ordinary univentricular repair strategy was performed; extracardiac total cavopulmonary connection was achieved at 18 months old. Catheterization performed 1 year after the Fontan procedure revealed the coronary sinus orifice atresia, diffuse coronary artery stenosis, and sinusoid formation of the coronary system...
August 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28732541/endobronchial-embolization-for-life-threatening-hemoptysis-with-endobronchial-watanabe-spigot
#20
Sze Shyang Kho, Swee Kim Chan, Mei Ching Yong, Siew Teck Tie
BACKGROUND: Massive hemoptysis is a common encounter in respiratory medicine. Bronchoscopy plays an important role in localizing the origin of bleeding, as well as endoscopic treatment of centrally located lesions. Endobronchial embolization is a novel technique enabling the management of hemoptysis arising even from peripheral lesions, via occlusion of the culprit bronchus, thereby securing the airway. Endobronchial Watanabe Spigot had been advocate in the treatment of bronchopleural fistula and the use of this novel technique had since then been expanded into the management of massive hemoptysis...
July 21, 2017: BMC Research Notes
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