keyword
https://read.qxmd.com/read/38614279/stereotactic-radiation-for-ultra-central-non-small-cell-lung-cancer-a-safety-and-efficacy-trial-sunset
#1
JOURNAL ARTICLE
E Giuliani Meredith, Edith Filion, Sergio Faria, Vijayananda Kundapur, Toni Vu Thi Trinh Thuc, Benjamin H Lok, Srinivas Raman, Houda Bahig, Joanna M Laba, Pencilla Lang, Alexander V Louie, Andrew Hope, George B Rodrigues, Andrea Bezjak, Marie-Pierre Campeau, Marie Duclos, Scott Bratman, Anand Swaminath, Rohan Salunkhe, Andrew Warner, David A Palma
INTRODUCTION: The use of stereotactic body radiotherapy (SBRT) for tumors in close proximity to the central mediastinal structures has been associated with a high risk of toxicity. This study (BLINDED FOR REVIEW) aimed to determine the maximally tolerated dose (MTD) of SBRT for ultra-central (UC) non-small cell lung carcinoma (NSCLC), using a time-to-event continual reassessment methodology (TITE-CRM). METHODS: Patients with T1-3N0M0 (≤ 6 cm) NSCLC were eligible...
April 11, 2024: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/38584038/azithromycin-reduces-bronchial-wall-thickening-in-infants-with-cystic-fibrosis
#2
JOURNAL ARTICLE
Yuxin Chen, Jean-Paul Charbonnier, Eleni-Rosalina Andrinopoulou, Peter D Sly, Stephen M Stick, Harm A W M Tiddens
BACKGROUND: COMBAT-CF showed that children aged 0-3 years treated with azithromycin did clinically better than placebo but there was no effect on CT-scores. We reanalysed CTs using an automatic bronchus-artery (BA) analysis. METHOD: Inspiratory and expiratory CTs at 12 and 36 months were analysed. BA-analysis measures BA-diameters: bronchial outer wall (Bout ), bronchial inner wall (Bin ), artery (A), and bronchial wall thickness (Bwt ) and computes BA-ratios: Bout /A and Bin /A for bronchial widening, Bwt /A and Bwa /Boa (bronchial wall area/bronchial outer area) for bronchial wall thickening...
April 6, 2024: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://read.qxmd.com/read/38580193/salvage-lung-retransplantation-en-bloc-double-lung-with-bronchial-artery-revascularization-for-bronchial-dehiscence-related-to-short-telomeres
#3
James J Yun, Shinya Unai, Marie M Budev, Bala Anandamurthy, Francisco Almeida, Jason Turowski, Ken R McCurry, Gosta Pettersson
No abstract text is available yet for this article.
April 3, 2024: Journal of Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/38579540/bronchial-arterial-chemoembolization-with-drug-eluting-beads-plus-sequential-chemotherapy-for-the-treatment-of-stage-iii-and-iv-lung-squamous-cell-carcinoma
#4
JOURNAL ARTICLE
Linqiang Lai, Fenfen Xu, Dengke Zhang, Jie Chen, Xihui Ying, Li Chen, Jiahao Wu, Jingjing Song, Weiwen Li, Jiansong Ji, Jianfei Tu
PURPOSE: This retrospective study aimed to investigate the effectiveness and safety of bronchial arterial chemoembolization with drug-eluting beads (DEB-BACE) plus chemotherapy versus chemotherapy alone in patients with stage III and IV lung squamous cell carcinoma (LSCC) who are not appropriate candidates for radiochemotherapy. MATERIALS AND METHODS: In this retrospective analysis, we screened all adult patients undergoing either DEB-BACE plus chemotherapy or chemotherapy alone for stage III or IV LCSS at authors' center from January 2018 to August 2021...
March 1, 2024: European Journal of Radiology
https://read.qxmd.com/read/38567592/effect-of-hyperbaric-oxygen-in-hepatopulmonary-syndrome-an-innovative-experimental-study
#5
JOURNAL ARTICLE
M Altinkaynak, G Simsek, Y Unlu, A Arslan, S S Erdem, A Kartal, M A Eryilmaz
OBJECTIVE: This study aimed to analyze the effect of hyperbaric oxygen treatment (HBOT) in hepatopulmonary syndrome (HPS). MATERIALS AND METHODS: Five-month-old female Wistar-Albino rats were randomly divided into three groups: Group I, the control group; Group II, the cirrhosis group; and Group III, the cirrhosis group + HBOT group. Rats were exposed to HBO sessions (2.4 atm./60 min) for 20 days. Animals were sacrificed 24 hours after the last HBO session...
March 2024: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/38548347/high-temporal-resolution-kinetic-modeling-of-lung-tumors-with-dual-blood-input-function-using-total-body-dynamic-pet
#6
JOURNAL ARTICLE
Yiran Wang, Yasser G Abdelhafez, Benjamin A Spencer, Rashmi Verma, Mamta Parikh, Nicholas Stollenwerk, Lorenzo Nardo, Terry Jones, Ramsey D Badawi, Simon R Cherry, Guobao Wang
The lungs are supplied by both the pulmonary arteries carrying deoxygenated blood originating from the right ventricle and the bronchial arteries carrying oxygenated blood downstream from the left ventricle. However, this effect of dual blood supply has never been investigated using PET, partially because the temporal resolution of conventional dynamic PET scans is limited. The advent of PET scanners with a long axial field of view, such as the uEXPLORER total-body PET/CT system, permits dynamic imaging with high temporal resolution (HTR)...
March 28, 2024: Journal of Nuclear Medicine
https://read.qxmd.com/read/38542162/differential-mitochondrial-oxidative-stress-and-inflammatory-responses-to-sars-cov-2-spike-protein-receptor-binding-domain-in-human-lung-microvascular-coronary-artery-endothelial-and-bronchial-epithelial-cells
#7
JOURNAL ARTICLE
Gabrielė Kulkovienė, Deimantė Narauskaitė, Agilė Tunaitytė, Augusta Volkevičiūtė, Zbigniev Balion, Olena Kutakh, Dovydas Gečys, Milda Kairytė, Martyna Uldukytė, Edgaras Stankevičius, Aistė Jekabsone
Recent evidence indicates that the SARS-CoV-2 spike protein affects mitochondria with a cell type-dependent outcome. We elucidate the effect of the SARS-CoV-2 receptor binding domain (RBD) on the mitochondrial network and cristae morphology, oxygen consumption, mitoROS production, and inflammatory cytokine expression in cultured human lung microvascular (HLMVECs), coronary artery endothelial (HCAECs), and bronchial epithelial cells (HBECs). Live Mito Orange staining, STED microscopy, and Fiji MiNa analysis were used for mitochondrial cristae and network morphometry; an Agilent XFp analyser for mitochondrial/glycolytic activity; MitoSOX fluorescence for mitochondrial ROS; and qRT-PCR plus Luminex for cytokines...
March 10, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38537623/successful-postnatal-tracheobronchoplasty-for-unilateral-congenital-high-airway-obstruction-syndrome-chaos-due-to-mainstem-bronchial-atresia
#8
Timothy M Crombleholme, Jennifer D Smith, Reenu Eapen, Maythem Al-Kubaisi, Kevin Magee
INTRODUCTION: Unilateral congenital high airway obstruction syndrome (CHAOS) is caused by a complete obstruction of a mainstem bronchus with resulting hyperinflation and accelerated growth of one lung, severe mediastinal shift and hydrops. Spontaneous perforation of the atresia has been observed in CHAOS which allows hydrops to resolve but hyperinflation, mediastinal shift and a critical airway obstruction persists as the perforation is usually pinhole-sized. CASE PRESENTATION: We present a case of unilateral CHAOS presenting at 26 2/7 weeks' with observed-to-expected total lung volume (O/E TLV) of 203% with spontaneous perforation occurring at 28 weeks' with resolution of hydrops but persistence of hyperinflation and mediastinal shift with an O/E TLV of 60...
March 27, 2024: Fetal Diagnosis and Therapy
https://read.qxmd.com/read/38533350/bronchial-artery-embolization-for-the-treatment-of-delayed-massive-hemoptysis-due-to-a-retained-bullet
#9
Atif Saleem Siddiqui
Bronchial artery embolization is a feasible option for treating hemoptysis caused by foreign objects in patients who are not candidates for surgery.
March 2024: Respirology Case Reports
https://read.qxmd.com/read/38527273/a-65-year-old-man-with-refractory-hemoptysis-associated-with-chronic-progressive-pulmonary-aspergillosis-who-failed-to-respond-to-combined-endobronchial-occlusion-and-bronchial-artery-embolization-a-case-report-and-literature-review
#10
REVIEW
Ryotaro Yoneoka, Kenichiro Takeda, Hajime Kasai, Toshihiko Sugiura, Kohei Shikano, Mitsuhiro Abe, Takuji Suzuki
BACKGROUND Hemoptysis due to airway hemorrhage is treated with hemostatic agents, bronchial artery embolization (BAE), or surgical resection. We present the case of a 65-year-old man with refractory hemoptysis associated with chronic progressive pulmonary aspergillosis (CPPA) who failed to respond to combined endobronchial occlusion (EBO) with endobronchial Watanabe spigot (EWS) and BAE. CASE REPORT A 63-year-old man was diagnosed with CPPA in the right upper lung and presented to our hospital 2 years later for hemoptysis at age 65...
March 13, 2024: American Journal of Case Reports
https://read.qxmd.com/read/38505050/prevalence-of-pulmonary-artery-dilation-in-non-cystic-fibrosis-bronchiectasis-a-computed-tomography-analysis-from-a-cohort-of-the-us-bronchiectasis-and-nontuberculous-mycobacteria-research-registry
#11
JOURNAL ARTICLE
Elham Karamooz, Anupama G Brixey, Chara E Rydzak, Steven L Primack, Sheila Markwardt, Alan F Barker
Although pulmonary artery (PA) dilation is independently associated with significant morbidity and mortality in patients with pulmonary diseases irrespective of diagnosed pulmonary hypertension, its relationship with nontuberculous mycobacteria (NTM) is unknown. The Bronchiectasis and NTM Research Registry is a multicenter registry created to foster research in non-cystic fibrosis (CF) bronchiectasis and NTM lung disease. The majority of patients with non-CF bronchiectasis at Oregon Health & Science University have NTM infections...
February 29, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38497130/value-of-multiplanar-reconstruction-in-multi-slice-computed-tomography-for-the-detection-of-foreign-body-in-the-pulmonary-artery-a-case-report
#12
JOURNAL ARTICLE
Qinxiang Mao, Zheng Lv, Qiuli Han, Wei Zhang
Multi-slice computed tomography (MSCT) is the primary method for the detection and visualization of foreign bodies in the pulmonary artery because it provides high sensitivity and accuracy. It is very difficult to diagnose a patient with a non-iatrogenic pulmonary artery foreign body who does not have a history of a penetrating trauma. This case report describes a 36-year-old male that presented with coughing and haemoptysis. Based on conventional coronal and cross-sectional CT, the foreign body was misdiagnosed as pulmonary tuberculosis and pulmonary artery thrombosis...
March 2024: Journal of International Medical Research
https://read.qxmd.com/read/38495527/3d-polarization-interference-holographic-histology-for-wavelet-based-differentiation-of-the-polycrystalline-component-of-biological-tissues-with-different-necrotic-states-forensic-applications
#13
JOURNAL ARTICLE
Alexander Ushenko, Alexander Dubolazov, Jun Zheng, Alexandra Litvinenko, Mykhaylo Gorsky, Yuriy Ushenko, Iryna Soltys, Olexander Salega, Zhebo Chen, Oleh Wanchuliak
SIGNIFICANCE: The interference-holographic method of phase scanning of fields of scattered laser radiation is proposed. The effectiveness of this method for the selection of variously dispersed components is demonstrated. This method made it possible to obtain polarization maps of biological tissues at a high level of depolarized background. The scale-selective analysis of such maps was used to determine necrotic changes in the optically anisotropic architectonics of biological tissues...
May 2024: Journal of Biomedical Optics
https://read.qxmd.com/read/38495261/intra-arterial-peptide-receptor-radionuclide-therapy-for-the-treatment-of-hepatic-neuroendocrine-tumor-metastases-hope-or-hype
#14
REVIEW
Michael V Khanjyan, Nicholas Fidelman
Peptide receptor radionuclide therapy (PRRT) confers significant progression-free survival advantage for patients with small bowel grade 1 and 2 well-differentiated neuroendocrine tumors (WD NET). PRRT may also be clinically beneficial for patients with NET of pancreatic, bronchial, and other sites of origin; patients with paragangliomas; as well as for patients with well-differentiated grade 3 NET. Direct intra-arterial (IA) administration of PRRT into the hepatic artery for patients with NET liver metastases may result in higher radiopharmaceutical dose and longer dwell time in the liver tumors while relatively sparing non-tumor liver tissue and other organs such as the kidneys and bone marrow when compared with intravenous (IV) administration...
February 2024: Seminars in Interventional Radiology
https://read.qxmd.com/read/38471708/rupture-of-a-bronchial-artery-pseudoaneurysm-after-radiotherapy
#15
JOURNAL ARTICLE
Nozomu Tsurumaki, Manabu Suzuki, Shinyu Izumi, Masayuki Hojo
No abstract text is available yet for this article.
March 12, 2024: BMJ Case Reports
https://read.qxmd.com/read/38455505/massive-hemoptysis-in-pregnancy-due-to-invasive-pulmonary-aspergillosis-with-pulmonary-tuberculosis-co-infection
#16
Nurul Aisyah Abd Rahman, Boon Hau Ng, Nik Nuratiqah Nik Abeed, Muhammad Ishamuddin Ismail, Mohamed Faisal Abdul Hamid, Andrea Ban Yu-Lin
A 37-year-old woman, 25 weeks pregnant, experienced sudden massive hemoptysis. She had a background history of systemic lupus erythematosus (SLE) and past pulmonary tuberculosis (PTB). Emergency intubation was necessary, and bronchoscopy revealed blood pooling in both main bronchi, with active bleeding from the right upper lobe bronchus. Urgent computed tomography (CT) angiography of the bronchial artery identified a bleeding source and was successfully embolized. Antifungal and anti-tuberculous therapy was initiated based on bronchoalveolar lavage results...
March 2024: Respirology Case Reports
https://read.qxmd.com/read/38448872/diagnostic-value-of-bedside-lung-ultrasound-and-12-zone-score-in-the-65-cases-of-neonatal-respiratory-distress-syndrome-and-its-severity
#17
JOURNAL ARTICLE
Peipei Huang, Deng Chen, Xiuxiang Liu, Xiang Zhang, Xiazi Song
OBJECTIVE: To explore the predictive value of bedside lung ultrasound score in the severity of neonatal respiratory distress syndrome (NRDS) and mechanical ventilation and extubation. METHODS: The clinical data of 65 neonates with NRDS and invasive mechanical ventilation diagnosed in the neonatal intensive care unit of our hospital from July 2021 to July 2022 were retrospectively analyzed. 65 neonates were included in the NRDS group, and 40 neonates with other common lung diseases were selected as the other lung disease groups...
March 6, 2024: Biomedical Engineering Online
https://read.qxmd.com/read/38446572/fetal-diagnosis-and-management-of-pulmonary-artery-sling-a%C3%A2-case-series
#18
JOURNAL ARTICLE
Scott Bennett, Lisa K Hornberger, Deborah Fruitman, Timothy J Bradley, Gitanjali P Mansukhani
OBJECTIVE: Pulmonary artery sling is a rare congenital anomaly accounting for 2% of all patients with vascular anomalies that cause airway obstruction. In the normal heart, the left (LPA) and right (RPA) pulmonary arteries arise in the intrapericardial space. However, in the pulmonary artery sling, the LPA trunk arises in the extrapericardial space from the posterior aspect of the mid RPA and courses posterior to the trachea causing tracheal compression and, at times, bronchial compression...
March 6, 2024: Prenatal Diagnosis
https://read.qxmd.com/read/38446026/sinoatrial-nodal-artery-fistula-to-bronchial-arteries-originating-from-the-right-coronary-artery-in-the-setting-of-chronic-bronchiectasis-and-coronary-artery-disease
#19
JOURNAL ARTICLE
Richard Casazza, Bilal Malik, Habib Hymie Chera, Enrico Montagna, Nailun Chang, Asiya Batool, Maryann Ruggierio
We present a 67-year-old male with past medical history of hyperlipidemia, hypertension, and emphysema, and who was a former smoker, with dyspnea on exertion and chest pain.
March 4, 2024: Journal of Invasive Cardiology
https://read.qxmd.com/read/38417388/anomalous-origin-of-the-right-coronary-artery-from-the-pulmonary-artery-in-a-staffordshire-bull-terrier
#20
M Garncarz, W Wtorkowska, M Parzeniecka-Jaworska, M Krzemiński, D Machola, K Sienkiewicz
An asymptomatic 17-month-old, 18.5-kg, male Staffordshire Bull Terrier was referred due to a heart murmur. Examination revealed a grade 3/6 left apical systolic and right apical 3/6 heart murmur. Echocardiography showed volume overload of the left ventricle and mild systolic dysfunction with a left-right flow over the interventricular septal region. Cardiac gated computed tomography revealed anomalous origin of the right coronary artery from the pulmonary artery, an extensive network of collateral blood vessels connected the right and left coronary arteries, with bronchial and left intercostal arteries also connected to the network of collateral blood vessels, markedly enlarged right and left coronary arteries and left coronary sinus...
February 8, 2024: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
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