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https://www.readbyqxmd.com/read/28239912/verrucae-planae-within-previous-xenograft-sites-of-burn-wounds
#1
Olivia Chen, Michelle Vernali Pearlstein, Dean S Morrell, Sarah B Corley
Burn injuries are known to compromise host immune defenses through disruption of mucocutaneous barriers and suppression of cell-mediated immune responses, which may render patients with burn injuries susceptible to viral infections in the days to years after an initial insult. We report a case of verrucae planae developing as a secondary condition confined to former xenograft sites in a child, appearing more than 3.5 years after initial second-degree burn injuries. Only a few reports have previously described the development of verrucae in former burn sites, with most reporting latency to onset of verrucae appearance of months rather than years...
February 27, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28239827/quantitative-difference-of-acute-intraoperative-expansion-in-various-body-regions
#2
E Raposio, N Bertozzi
OBJECTIVE: To investigate the efficacy of intraoperative sustained limited expansion (ISLE) by examining the ex vivo biomechanical properties of acutely expanded skin flaps. MATERIALS AND METHODS: Fourteen fresh male cadavers were tested. On both sides of each cadaver, a 4 × 10 cm, the laterally based flap was raised at the external auditory canal of the scalp and a 15 × 8 cm, the proximately based flap was raised at the lateral arm, anterior thorax, and lateral thigh...
February 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28239579/neck-trauma-ent-prospects
#3
Kavita Sachdeva, Aparaajita Upadhyay
Neck trauma is a very important surgical emergency faced by ENT surgeons in day to day practice. They are potentially life threatening conditions due to the presence of many vital structures in this area. Timely presentation to the referral centre and proper multidisciplinary approach towards management plays a pivotal role in the healing pattern of the wound and prevention of serious complication like shock, sepsis, laryngeal stenosis or fistula formation. A retrospective study was done in ENT Department, NSCB Medical College, Jabalpur, Madhya Pradesh, India during the period of 2014-2016...
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28239573/role-of-buccal-pad-of-fat-in-reconstruction-of-the-buccal-mucosa-defects
#4
A Sagayaraj, N Divya Jyothi, S M Azeem Mohiyuddin, Ravindra P Deo, B Vageesh Padiyar
Carcinoma buccal mucosa is the most common oral cavity cancer in India. Following excision of these lesions the defects can be reconstructed using various reconstructive techniques. Buccal pad of fat has been successfully used in the reconstruction of small palatal defects and in the closure of the oro antral fistula. This study aims at evaluating the role of buccal pad of fat in reconstruction of defects following excision of the small to medium premalignant lesions and T1-T2 malignant lesions of buccal mucosa...
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28239571/comparison-of-elective-minimally-invasive-with-conventional-surgical-tracheostomy-in-adults
#5
Rajiv Ranganath Sanji, Chandrakiran Channegowda, Sanjay B Patil
Minimally invasive techniques were used for tracheostomy including small horizontal skin incision, limited soft tissue dissection and no suturing. A Retrospective analysis of case sheets of patients who underwent elective tracheostomy by the first and second authors at M S Ramaiah Hospitals in Bangalore between 1st May 2010 and 1st May 2015 was done to compare the result of elective conventional open surgical tracheostomy using midline vertical skin incision with minimally invasive tracheostomy using a short horizontal incision...
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28239493/a-review-on-polymeric-hydrogel-membranes-for-wound-dressing-applications-pva-based-hydrogel-dressings
#6
REVIEW
Elbadawy A Kamoun, El-Refaie S Kenawy, Xin Chen
This review presents the past and current efforts with a brief description on the featured properties of hydrogel membranes fabricated from biopolymers and synthetic ones for wound dressing applications. Many endeavors have been exerted during past ten years for developing new artificial polymeric membranes, which fulfill the demanded conditions for the treatment of skin wounds. This review mainly focuses on representing specifications of ideal polymeric wound dressing membranes, such as crosslinked hydrogels compatible with wound dressing purposes...
May 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/28239398/a-pilot-randomized-controlled-study-of-nanocrystalline-silver-manuka-honey-and-conventional-dressing-in-healing-diabetic-foot-ulcer
#7
Ka-Kit Tsang, Enid Wai-Yung Kwong, Tony Shing-Shun To, Joanne Wai-Yee Chung, Thomas Kwok-Shing Wong
Nanocrystalline silver (nAg) and Manuka honey (MH) dressing have increasing popularity for treating diabetic foot ulcer (DFU). This study was an open-label randomized controlled trial with three parallel groups' design in examining the preliminary effectiveness of nAg against MH and conventional dressing in healing DFU in terms of ulcer healing, ulcer infection, and inflammation. 31 participants (11 in the nAg group, 10 in the MH group, and 10 in the convention group) diagnosed with type 2 diabetes were enrolled...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28238941/theoretical-and-practical-aspects-of-using-fetal-fibroblasts-for-skin-regeneration
#8
REVIEW
Meirong Li, Yali Zhao, Haojie Hao, Weidong Han, Xiaobing Fu
Cutaneous wounding in late-gestational fetal or postnatal humans results in scar formation without any skin appendages. Early or mid- gestational skin healing in humans is characterized by the absence of scaring in a process resembling regeneration. Tremendous cellular and molecular mechanisms contribute to this distinction, and fibroblasts play critical roles in scar or scarless wound healing. This review discussed the different repair mechanisms involved in wound healing of fibroblasts at different developmental stages and further confirmed that fetal fibroblast transplantation resulted in reduced scar healing in vivo...
February 23, 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/28238041/electrospinning-of-bioactive-wound-healing-nets
#9
Heinz C Schröder, Emad Tolba, Bärbel Diehl-Seifert, Xiaohong Wang, Werner E G Müller
The availability of appropriate dressings for treatment of wounds, in particular chronic wounds, is a task that still awaits better solutions than provided by currently applied materials. The method of electrospinning enables the fabrication of novel materials for wound dressings due to the high surface area and porosity of the electrospun meshes and the possibility to include bioactive ingredients. Recent results show that the incorporation of biologically active inorganic polyphosphate microparticles and microspheres and synergistically acting retinoids into electrospun polymer fibers yields biocompatible and antibacterial mats for potential dressings with improved wound-healing properties...
2017: Progress in Molecular and Subcellular Biology
https://www.readbyqxmd.com/read/28237967/heterozygous-vangl2-looptail-mice-reveal-novel-roles-for-the-planar-cell-polarity-pathway-in-adult-lung-homeostasis-and-repair
#10
Thanushiyan Poobalasingam, Laura L Yates, Simone A Walker, Miguel Pereira, Nina Y Gross, Akmol Ali, Maria Kolatsi-Joannou, Marjo-Riitta Jarvelin, Juha Pekkanen, Eugenia Papakrivopoulou, David A Long, Mark Griffiths, Darcy Wagner, Melanie Königshoff, Matthew Hind, Cosetta Minelli, Clare M Lloyd, Charlotte H Dean
Lung diseases impose a huge economic and health burden worldwide. A key aspect of several adult lung diseases, such as Idiopathic pulmonary fibrosis (IPF) and Chronic Obstructive pulmonary Disease (COPD), including emphysema, is aberrant tissue repair, which leads to an accumulation of damage and impaired respiratory function. Currently, there are few effective treatments available for these diseases and their incidence is rising.The Planar Cell Polarity (PCP) pathway is critical for the embryonic development of many organs, including kidney and lung...
February 24, 2017: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/28237760/differentiating-suicide-decedents-who-died-using-firearms-from-those-who-died-using-other-methods
#11
Michael D Anestis, Lauren R Khazem, Joye C Anestis
Studies have documented a link between gun ownership and suicide, but little is known about characteristics of those most likely to use a gun in a suicide attempt rather than alternative methods. We examined which factors differentiate suicide decedents who died using a gun from those who died by other methods. We further examined whether such findings are consistent within the subcomponent of our larger sample comprised entirely of gun owning suicide decedents. Data reflect 267 suicide decedents, with data provided by individuals who identified as having lost someone to suicide (loss survivors)...
February 22, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28237566/preliminary-results-and-learning-curve-of-the-minimally-invasive-chevron-akin-operation-for-hallux-valgus
#12
Charlie R J Jowett, Harvinder S Bedi
Minimally invasive surgery is increasing in popularity. It is relevant in hallux valgus surgery owing to the potential for reduced disruption of the soft tissues and improved wound healing. We present our results and assess the learning curve of the minimally invasive Chevron Akin operation for hallux valgus. A total of 120 consecutive feet underwent minimally invasive Chevron Akin for symptomatic hallux valgus, of which 14 were excluded. They were followed up for a mean of 25 (range 18 to 38) months. The patients were clinically assessed using the American Orthopaedic Foot and Ankle Society score...
February 22, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28237520/smoking-as-a-risk-factor-for-breast-reduction-an-analysis-of-13-503-cases
#13
Jeffery S Hillam, Emily A Borsting, Jimmy H Chim, Seth R Thaller
BACKGROUND: Reduction mammaplasty is one of the most common reconstructive procedures performed by plastic surgeons. Over 100,000 procedures are performed annually. Although important for relieving the painful symptoms associated with macromastia, complication rates of this procedure are not insignificant. They are reported in up to half the cases. Reported risk factors for adverse outcomes include obesity, preoperative wound infection, and advanced American Society of Anesthesiologists status...
January 16, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28237425/aqueous-angiography-in-living-nonhuman-primates-shows-segmental-pulsatile-and-dynamic-angiographic-aqueous-humor-outflow
#14
Alex S Huang, Meng Li, Diya Yang, Huaizhou Wang, Ningli Wang, Robert N Weinreb
PURPOSE: To evaluate the feasibility of safely performing aqueous angiography in intact eyes of living nonhuman primates (NHPs) for evaluating aqueous humor outflow and segmental patterns. DESIGN: Cross-sectional, observational study. SUBJECTS: Six nonhuman primates. METHODS: Aqueous angiography was performed in 6 nonhuman primates. After anesthesia, an anterior chamber (AC) maintainer was placed through a temporal 1-mm side-port wound...
February 22, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28236918/morbidity-and-mortality-after-emergency-lower-extremity-embolectomy
#15
Sergio Casillas-Berumen, Lili Sadri, Alik Farber, Mohammad H Eslami, Jeffrey A Kalish, Denis Rybin, Gheorghe Doros, Jeffrey J Siracuse
OBJECTIVE: Emergency lower extremity embolectomy is a common vascular surgical procedure that has poorly defined outcomes. Our goal was to define the perioperative morbidity for emergency embolectomy and develop a risk prediction model for perioperative mortality. METHODS: The American College of Surgeons National Surgical Quality Improvement database was queried to identify patients undergoing emergency unilateral and lower extremity embolectomy. Patients with previous critical limb ischemia, bilateral embolectomy, nonemergency indication, and those undergoing concurrent bypass were excluded...
March 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28236912/the-application-of-the-society-for-vascular-surgery-wound-ischemia-and-foot-infection-wifi-classification-to-stratify-amputation-risk
#16
EDITORIAL
Joseph L Mills
No abstract text is available yet for this article.
March 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28236701/an-alternative-poldip3-transcript-promotes-hepatocellular-carcinoma-progression
#17
Xiao-Ning Liu, Ji-Hang Yuan, Tian-Tian Wang, Wei Pan, Shu-Han Sun
Alternative splicing plays critical roles in many pathophysiological processes and splicing dysregulation is a hallmark of cancer. The different isoforms may have significantly different effects on cancers. POLDIP3 is a target of ribosomal protein S6 kinase 1, and regulates DNA replication and mRNA translation. In this study, we measured the expression of an alternative POLDIP3 transcript (POLDIP3-β), which lacks exon 3 and 29 amine acids, in clinical hepatocellular carcinoma (HCC) tissues. The roles of POLDIP3-β on HCC cell proliferation, apoptosis, and migration were assessed by Glo cell viability assays, Ethynyl deoxyuridine incorporation assays, colony formation assays, TUNEL assays, Annexin V-propidium iodide staining and flow cytometry, transwell assays, wound healing assays, and in vivo xenograft growth...
February 22, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28236536/-streptococcus-milleri-an-unusual-cause-of-skull-extensive-osteomyelitis-in-an-immunocompetent-patient
#18
C Duquenne, E Dernis, A Zehrouni, A Bizon, M Duquenne
INTRODUCTION: Streptococcus milleri (Streptococcus anginosus, intermedius and constellatus) are commensal organisms, which can become pathogenic and cause infection with frequent abscess formation, local or metastatic extension. Osteomyelitis of the skull has been rarely reported in this type of infection. CASE REPORT: Skull osteomyelitis due to Streptococcus milleri is reported in a 61-year-old immunocompetent man without any medical history, occurring 10 months after a head injury without any wound or complication at initial presentation...
February 21, 2017: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/28236453/anti-inflammatory-ent-kaurenoic-acids-and-their-glycosides-from-gochnatia-decora
#19
Mi Zhang, Chenxing Zhao, Weifeng Dai, Jing He, Shiyun Jiao, Baocai Li
Nineteen ent-kaurane diterpenes were isolated and identified from the barks of Gochnatia decora (Kurz) A. L. Cabrera (Compositae), which has been used as an ethnic medicine for treating cough, asthma and wounds in southwestern China. Among them, six compounds are previously undescribed ent-kaurenoic acids, and a known compound, 7β,15β-dihydroxy-ent-kaur-16-en-19-oic acid, was obtained for the first time from nature. Based on its traditional effects in Chinese folk, the potential anti-inflammatory activities of its methanol extracts (ME) and isolated diterpenes were evaluated by the tests of the xylene-induced ear swelling in mice, lipopolysaccharide (LPS)-induced nitric oxide (NO) production in mouse macrophage cellular RAW 264...
February 21, 2017: Phytochemistry
https://www.readbyqxmd.com/read/28236403/phytochemistry-pharmacology-and-therapeutic-uses-of-black-seed-nigella-sativa
#20
REVIEW
Wesam Kooti, Zahra Hasanzadeh-Noohi, Naim Sharafi-Ahvazi, Majid Asadi-Samani, Damoon Ashtary-Larky
Black seed (Nigella sativa) is an annual flowering plant from Ranunculaceae family, native to southwest Asia. This plant has many food and medicinal uses. The use of its seeds and oil is common for treatment of many diseases, including rheumatoid arthritis, asthma, inflammatory diseases, diabetes and digestive diseases. The purpose of this study was to provide a comprehensive review on the scientific reports that have been published about N. sativa. The facts and statistics presented in this review article were gathered from the journals accessible in creditable databases such as Science Direct, Medline, PubMed, Scopus, EBSCO, EMBASE, SID and IranMedex...
October 2016: Chinese Journal of Natural Medicines
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