Aya Khaled, Esraa Ahmed, Mohamed Mamdouh, Hager Saad, Aya Mohamed, Marina Sobhy, Diletta Piatti, Miral Sabry, Muhammed A Saad, Omar M Sabry, Giovanni Caprioli
Hypertension is a serious concern as it is one of the causes of kideny failure and pulmonary fibrosis. An important therapeutic strategy for treating chronic hypertension is to inhibit the angiotensin converting enzyme (ACE). ACE inhibition reduces kidney damage, pulmonary artery pressure, and high blood pressure. Due to their high efficacy and low risk of side effects, natural renin-angiotensin system inhibitors have drawn increasing attention over the past decades. Alkaloids, amino acids, anthocyanidins, flavonoids, glucosinolates, isoflavonoids, phenolic acids, polyphenolics, and triterpenoids are among the bioactive metabolites pocessing an impressive ACE inhibitory activity...
December 2023: Phytotherapy Research: PTR