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https://www.readbyqxmd.com/read/28716165/frontal-assessment-battery-in-parkinson-s-disease-validity-and-morphological-correlates
#1
Ondrej Bezdicek, Filip Růžička, Adela Fendrych Mazancova, Jan Roth, Pavel Dušek, Karsten Mueller, Evžen Růžička, Robert Jech
OBJECTIVES: Executive dysfunction is a common feature in Parkinson's disease (PD). However, there is a lack of brief validated instruments for executive dysfunction in PD. METHODS: The aim of the present study was to assess the relation of Frontal Assessment Battery (FAB) scores to age and education, to verify the utility of FAB in the evaluation of executive dysfunction in PD and to differentiate between controls (n=41), PD patients with normal cognition (PD-NC; n=41; Hoehn and Yahr stages 2-3) and PD with mild cognitive impairment (PD-MCI; n=32; Hoehn and Yahr stages 2-3)...
July 18, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28715675/resting-state-brain-networks-in-patients-with-parkinson-s-disease-and-impulse-control-disorders
#2
Alessandro Tessitore, Gabriella Santangelo, Rosa De Micco, Alfonso Giordano, Simona Raimo, Marianna Amboni, Fabrizio Esposito, Paolo Barone, Gioacchino Tedeschi, Carmine Vitale
INTRODUCTION: To investigate intrinsic neural networks connectivity changes in Parkinson's disease (PD) patients with and without impulse control disorders (ICD). METHODS: Fifteen patients with PD with ICD (ICD+), 15 patients with PD without ICD (ICD-) and 24 age and sex-matched healthy controls (HC) were enrolled in the study. To identify patients with and without ICD and/or punding, we used the Minnesota Impulsive Disorders Interview (MIDI) and a clinical interview based on diagnostic criteria for each symptom...
June 24, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28713925/the-atrophy-of-white-and-gray-matter-volume-in-patients-with-comitant-strabismus-evidence-from-a-voxel-based-morphometry-study
#3
Jun Ouyang, Lu Yang, Xin Huang, Yu-Lin Zhong, Pei-Hong Hu, Ying Zhang, Chong-Gang Pei, Yi Shao
To compare the difference in white matter volume (WMV) and gray matter volume (GMV) between the comitant strabismus (CS) patients and health controls by voxel-based morphometry (VBM) and the relationship with behavioral performance. A total of 20 patients with comitant strabismus (10 males and 10 females), and 20 healthy subjects (10 males and 10 females) with matched age, sex status underwent magnetic resonance examination. The authors analyzed the original 3D T1 brain images using the VBM module. The comitant strabismus groups were compared with the control groups for the GMW and WMV of the entire brain...
July 15, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28706481/adverse-effects-of-the-apolipoprotein-e-%C3%AE%C2%B54-allele-on-episodic-memory-task-switching-and-gray-matter-volume-in-healthy-young-adults
#4
Jianfei Nao, Hongzan Sun, Qiushi Wang, Shuang Ma, Shuo Zhang, Xiaoyu Dong, Ying Ma, Xiaoming Wang, Dongming Zheng
Many studies have shown that healthy elderly subjects and patients with Alzheimer's disease (AD) who carry the apolipoprotein E (ApoE) ε4 allele have worse cognitive function and more severe brain atrophy than non-carriers. However, it remains unclear whether this ApoE polymorphism leads to changes of cognition and brain morphology in healthy young adults. In this study, we used an established model to measure verbal episodic memory and core executive function (EF) components (response inhibition, working memory and task switching) in 32 ApoE ε4 carriers and 40 non-carriers between 20 years and 40 years of age...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28697581/altered-gray-matter-volume-and-functional-connectivity-of-the-motor-network-in%C3%A2-young%C3%A2-divers
#5
Xia Liu, Liansheng Liu, Fen Hou, Zhifeng Zhou, Qingying Wu, Hengguo Li
BACKGROUND: Motor learning and professional sports training can induce plastic changes in brain structures that are associated with distinct training demands. OBJECTIVE: To testify the hypothesis of that regional gray matter structures in the motor-related cortex and its functional connectivity (FC) are altered in young divers. METHODS: We undertook T1-voxel-based morphometry (VBM) structural and resting-state functional magnetic resonance imaging in groups of diving athletes (DAs) and demographically-matched healthy controls...
July 7, 2017: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/28696183/visual-system-involvement-in-patients-with-newly-diagnosed-parkinson-disease
#6
Alessandro Arrigo, Alessandro Calamuneri, Demetrio Milardi, Enricomaria Mormina, Laura Rania, Elisa Postorino, Silvia Marino, Giuseppe Di Lorenzo, Giuseppe Pio Anastasi, Maria Felice Ghilardi, Pasquale Aragona, Angelo Quartarone, Michele Gaeta
Purpose To assess intracranial visual system changes of newly diagnosed Parkinson disease in drug-naïve patients. Materials and Methods Twenty patients with newly diagnosed Parkinson disease and 20 age-matched control subjects were recruited. Magnetic resonance (MR) imaging (T1-weighted and diffusion-weighted imaging) was performed with a 3-T MR imager. White matter changes were assessed by exploring a white matter diffusion profile by means of diffusion-tensor imaging-based parameters and constrained spherical deconvolution-based connectivity analysis and by means of white matter voxel-based morphometry (VBM)...
July 11, 2017: Radiology
https://www.readbyqxmd.com/read/28690225/-grey-matter-concentration-revealed-by-voxel-based-morphometry-in-individuals-with-cognitive-vulnerability-to-depression
#7
Shuwen Yuan, Hui Lei, Shuqiao Yao, Xiaocui Zhang
To explore the grey matter concentration in individuals with cognitive vulnerability to depression.
 Methods: Thirty individuals with cognitive vulnerability to depression and thirty age- and gender-matched healthy controls were enrolled in this study, and they were subjected to magnetic resonance imaging (MRI) examination. The grey matter concentration differences were compared between the two groups by using voxel-based morphometry (VBM) following MRI.
 Results: Individuals with cognitive vulnerability to depression showed significantly lower grey matter density in bilateral insular, left cerebellum, right supplementary motor area, and left precentral gyrus than those in the healthy controls, while the healthy controls showed significantly lower grey density in the right inferior frontal gyrus, right middle frontal gyrus, and left cuneus than those in the individuals with cognitive vulnerability to depression...
June 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28677058/structural-changes-in-parkinson-s-disease-voxel-based-morphometry-and-diffusion-tensor-imaging-analyses-based-on-123-i-mibg-uptake
#8
Kazufumi Kikuchi, Akio Hiwatashi, Osamu Togao, Koji Yamashita, Ryo Somehara, Ryotaro Kamei, Shingo Baba, Hiroo Yamaguchi, Jun-Ichi Kira, Hiroshi Honda
OBJECTIVE: Patients with Parkinson's disease (PD) may exhibit symptoms of sympathetic dysfunction that can be measured using (123)I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy. We investigated the relationship between microstructural brain changes and (123)I-MIBG uptake in patients with PD using voxel-based morphometry (VBM) and diffusion tensor imaging (DTI) analyses. METHODS: This retrospective study included 24 patients with PD who underwent 3 T magnetic resonance imaging and (123)I-MIBG scintigraphy...
July 4, 2017: European Radiology
https://www.readbyqxmd.com/read/28668411/functional-and-structural-changes-in-gray-matter-of-parkinson-s-disease-patients-with-mild-cognitive-impairment
#9
Boyu Chen, Shanshan Wang, Wenge Sun, Xiuli Shang, Hu Liu, Guohao Liu, Jie Gao, Guoguang Fan
BACKGROUND AND PURPOSE: Cognitive impairment is a common non-motor complication of Parkinson's disease (PD). To investigate cognitive-related changes of gray matter (GM) structure and function in PD using voxel-based morphometry (VBM) and resting state functional connectivity (RSFC). MATERIALS AND METHODS: Resting state functional magnetic resonance imaging (rs-fMRI) and 3D-T1-weighted MRI scans were obtained from 21 PD patients with mild cognitive impairment (PD-MCI), 11 PD patients with normal cognitive function (PD-NC), and 21 healthy controls (HC)...
August 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28667881/grey-matter-density-changes-of-structures-involved-in-posttraumatic-stress-disorder-ptsd-after-recovery-following-eye-movement-desensitization-and-reprocessing-emdr-therapy
#10
Sarah Boukezzi, Myriam El Khoury-Malhame, Guillaume Auzias, Emmanuelle Reynaud, Pierre-François Rousseau, Emmanuel Richard, Xavier Zendjidjian, Jacques Roques, Nathalie Castelli, Nadia Correard, Valérie Guyon, Caroline Gellato, Jean-Claude Samuelian, Aida Cancel, Magali Comte, Marianne Latinus, Eric Guedj, Stéphanie Khalfa
Recovery of stress-induced structural alterations in Posttraumatic Stress Disorder (PTSD) remains largely unexplored. This study aimed to determine whether symptoms improvement is associated with grey matter (GM) density changes of brain structures involved in PTSD. Two groups of PTSD patients were involved in this study. The first group was treated with Eye Movement Desensitization and Reprocessing (EMDR) therapy and recovered from their symptoms (recovery group) (n = 11); Patients were scanned prior to therapy (T1), one week (T2) and five months after the end of therapy (T3)...
June 19, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28667375/different-patterns-of-gray-matter-density-in-early-and-middle-late-onset-parkinson-s-disease-a-voxel-based-morphometry-study
#11
Min Xuan, Xiaojun Guan, Peiyu Huang, Zhujing Shen, Quanquan Gu, Xinfeng Yu, Xiaojun Xu, Wei Luo, Minming Zhang
Early-onset Parkinson's disease (EOPD) has a clinical course and characteristics distinct from middle-late-onset Parkinson's disease (M-LOPD). Although many studies have investigated these differences, the neural mechanisms of these characteristics remain unclear. This study aimed to investigate the morphological differences, and their related clinical significance, between EOPD and M-LOPD patients. We recruited two groups of patients, 28 EOPD patients and 37 M-LOPD patients, and two age- and sex-matched control groups (23 controls in each group)...
June 30, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28659776/cholinergic-potentiation-and-audiovisual-repetition-imitation-therapy-improve-speech-production-and-communication-deficits-in-a-person-with-crossed-aphasia-by-inducing-structural-plasticity-in-white-matter-tracts
#12
Marcelo L Berthier, Irene De-Torres, José Paredes-Pacheco, Núria Roé-Vellvé, Karl Thurnhofer-Hemsi, María J Torres-Prioris, Francisco Alfaro, Ignacio Moreno-Torres, Diana López-Barroso, Guadalupe Dávila
Donepezil (DP), a cognitive-enhancing drug targeting the cholinergic system, combined with massed sentence repetition training augmented and speeded up recovery of speech production deficits in patients with chronic conduction aphasia and extensive left hemisphere infarctions (Berthier et al., 2014). Nevertheless, a still unsettled question is whether such improvements correlate with restorative structural changes in gray matter and white matter pathways mediating speech production. In the present study, we used pharmacological magnetic resonance imaging to study treatment-induced brain changes in gray matter and white matter tracts in a right-handed male with chronic conduction aphasia and a right subcortical lesion (crossed aphasia)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28657751/quantifying-van-der-waals-interactions-in-layered-transition-metal-dichalcogenides-from-pressure-enhanced-valence-band-splitting
#13
Penghong Ci, Yabin Chen, Jun Kang, Ryuji Suzuki, Hwan Sung Choe, Joonki Suh, Changhyun Ko, Taegyun Park, Ke Shen, Yoshihiro Iwasa, Sefaattin Tongay, Joel W Ager, Lin-Wang Wang, Junqiao Wu
van der Waals (vdW) forces, despite being relatively weak, hold the layers together in transition metal dichalcogenides (TMDs) and play a key role in their band structure evolution, hence profoundly affecting their physical properties. In this work, we experimentally probe the vdW interactions in MoS2 and other TMDs by measuring the valence band maximum (VBM) splitting (Δ) at K point as a function of pressure in a diamond anvil cell. As high pressure increases interlayer wave function coupling, the VBM splitting is enhanced in 2H-stacked MoS2 multilayers but, due to its specific geometry, not in 3R-stacked multilayers, hence allowing the interlayer contribution to be separated out of the total VBM splitting, as well as predicting a negative pressure (2...
July 3, 2017: Nano Letters
https://www.readbyqxmd.com/read/28656618/sulfur-doped-graphene-oxide-quantum-dots-as-photocatalysts-for-hydrogen-generation-in-the-aqueous-phase
#14
Tung-Kung Wu, Jacek Gliniak, Jia-Hoa Lin, Yi-Ting Chen, Chuen-Ru Li, Efat Jokar, Chin-Hao Chang, Chun-Sheng Peng, Jui-Nien Lin, Wan-Hsiang Lien, Hui-Min Tsai
Sulfur-doped graphene oxide quantum dots (S-GO QDs) have been synthesized and investigated for efficient photocatalytic hydrogen generation application. The UV-vis, FT-IR, and photoluminescent spectra of the synthesized S-GO QDs exhibit three absorption bands at 333, 395, and 524 nm, characteristic of C=S and C-S stretching vibration signals at 1075 cm-1 and 690 cm-1, and two excitation wavelength independent emission signals with maxima at 451 and 520 nm, respectively, confirming the successful doping of S atom into the GO QDs...
June 28, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28656145/reduction-of-interhemispheric-functional-brain-connectivity-in-early-blindness-a-resting-state-fmri-study
#15
Fen Hou, Xia Liu, Zhifeng Zhou, Jingyi Zhou, Hengguo Li
OBJECTIVE: The purpose of this study was to investigate the resting-state interhemispheric functional connectivity in early blindness by using voxel-mirrored homotopic connectivity (VMHC). MATERIALS AND METHODS: Sixteen early blind patients (EB group) and sixteen age- and gender-matched sighted control volunteers (SC group) were recruited in this study. We used VMHC to identify brain areas with significant differences in functional connectivity between different groups and used voxel-based morphometry (VBM) to calculate the individual gray matter volume (GMV)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28645750/the-effect-of-future-time-perspective-on-delay-discounting-is-mediated-by-the-gray-matter-volume-of-vmpfc
#16
Yiqun Guo, Zhiyi Chen, Tingyong Feng
Although several previous studies have shown that individuals' attitude towards time could affect their intertemporal preference, little is known about the neural basis of the relation between time perspective (TP) and delay discounting. In the present study, we quantified the gray matter (GM) cortical volume using voxel-based morphometry (VBM) methods to investigate the effect of TP on delay discounting (DD) across two independent samples. For group 1 (102 healthy college students; 46 male; 20.40 ± 1.87 years), behavioral results showed that only Future TP was a significant predictor of DD, and higher scores on Future TP were related to lower discounting rates...
June 21, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28612183/impairments-in-walking-ability-dexterity-and-cognitive-function-in-multiple-sclerosis-are-associated-with-different-regional-cerebellar-gray-matter-loss
#17
Matthias Grothe, Martin Lotze, Sönke Langner, Alexander Dressel
Both histological and neuroimaging studies highlight the role of the cerebellum in multiple sclerosis (MS). There is at least some evidence for associations of cerebellar gray matter (GM) loss with motor and cognitive ability. We therefore correlated motor and cognitive ability scores (the multiple sclerosis functional composite MSFC) with regional cerebellar GM volumes. We used voxel-based morphometry (VBM) to assess the regional GM volume loss in a cohort of 45 MS patients. For the regression analysis, we used the clinical subscores of the multiple sclerosis functional composite (25-ft walk test (T25FW), nine-hole peg test (9HPT), paced auditory serial addition task (PASAT))...
June 13, 2017: Cerebellum
https://www.readbyqxmd.com/read/28608601/brain-structural-properties-predict-psychologically-mediated-hypoalgesia-in-an-8-week-sham-acupuncture-treatment-for-migraine
#18
Jixin Liu, Junya Mu, Qianqian Liu, Wanghuan Dun, Ming Zhang, Jie Tian
Neuroimaging studies described brain structural changes that comprise the mechanisms underlying individual differences in migraine development and maintenance. However, whether such interindividual variability in migraine was observed in a pretreatment scan is a predisposition for subsequent hypoalgesia to placebo treatment that remains largely unclear. Using T1-weighted imaging, we investigated this issue in 50 healthy controls (HC) and 196 patients with migraine without aura (MO). An 8-week double-blinded, randomized, placebo-controlled acupuncture was used, and we only focused on the data from the sham acupuncture group...
June 13, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28608049/unsatisfied-relatedness-not-competence-or-autonomy-increases-trait-anger-through-the-right-amygdala
#19
Yinan Wang, Feng Kong, Xiangzhen Kong, Yuanfang Zhao, Danhua Lin, Jia Liu
Anger is a common negative emotion in social life. Behavioral research suggests that unsatisfied relatedness, autonomy, and competence are related to anger. However, it remains unclear whether these unsatisfied needs all contribute to anger or just a particular unsatisfied need is the main source of anger. In addition, little is known about the neural substrate between unsatisfied needs and anger. To address these two questions, we used voxel-based morphometry (VBM) to explore the neural substrate underlying the relation between unsatisfied needs and trait anger...
June 12, 2017: Cognitive, Affective & Behavioral Neuroscience
https://www.readbyqxmd.com/read/28606629/neural-substrates-underlying-balanced-time-perspective-a-combined-voxel-based-morphometry-and-resting-state-functional-connectivity-study
#20
Yiqun Guo, Zhiyi Chen, Tingyong Feng
Balanced time perspective (BTP), which is defined as a mental ability to switch flexibly among different time perspectives Zimbardo and Boyd (1999), has been suggested to be a central component of positive psychology Boniwell and Zimbardo (2004). BTP reflects individual's cognitive flexibility towards different time frames, which leads to many positive outcomes, including positive mood, subjective wellbeing, emotional intelligence, fluid intelligence, and executive control. However, the neural basis of BTP is still unclear...
June 9, 2017: Behavioural Brain Research
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