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https://www.readbyqxmd.com/read/29330136/white-matter-volume-loss-in-amyotrophic-lateral-sclerosis-a-meta-analysis-of-voxel-based-morphometry-studies
#1
REVIEW
Guangxiang Chen, Baiwan Zhou, Hongyan Zhu, Weihong Kuang, Feng Bi, Hua Ai, Zhongwei Gu, Xiaoqi Huang, Su Lui, Qiyong Gong
Structural neuroimaging studies of white matter (WM) volume in amyotrophic lateral sclerosis (ALS) using voxel-based morphometry (VBM) have yielded inconsistent findings. This study aimed to perform a quantitative voxel-based meta-analysis using effect-size signed differential mapping (ES-SDM) to establish a statistical consensus between published studies for WM volume alterations in ALS. The pooled meta-analysis revealed significant WM volume losses in the bilateral supplementary motor areas (SMAs), bilateral precentral gyri (PGs), left middle cerebellar peduncle and right cerebellum in patients with ALS, involving the corticospinal tract (CST), interhemispheric fibers, subcortical arcuate fibers, projection fibers to the striatum and cortico-ponto-cerebellar tract...
January 9, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29329055/altered-brain-structure-in-women-with-premenstrual-syndrome
#2
Peng Liu, Ying Wei, Yingying Fan, Ru Li, Yanfei Liu, Geliang Wang, Yichen Wei, Yong Pang, Demao Deng, Wei Qin
BACKGROUND: Functional brain abnormalities have been noted in premenstrual syndrome (PMS). However, the brain structural alterations related to PMS remain unclear. This study aimed to identify possible abnormalities in gray matter (GM) volumes and structural covariance patterns among PMS patients. METHODS: Structural magnetic resonance imaging data were obtained from 20 PMS patients and 20 healthy controls. Voxel-based morphometry (VBM) analysis was applied to examine GM volumes changes between the two groups...
January 3, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29322264/cerebral-gray-matter-volume-in-patients-with-chronic-migraine-correlations-with-clinical-features
#3
Gianluca Coppola, Barbara Petolicchio, Antonio Di Renzo, Emanuele Tinelli, Cherubino Di Lorenzo, Vincenzo Parisi, Mariano Serrao, Valentina Calistri, Stefano Tardioli, Gaia Cartocci, Anna Ambrosini, Francesca Caramia, Vittorio Di Piero, Francesco Pierelli
BACKGROUND: To date, few MRI studies have been performed in patients affected by chronic migraine (CM), especially in those without medication overuse. Here, we performed magnetic resonance imaging (MRI) voxel-based morphometry (VBM) analyses to investigate the gray matter (GM) volume of the whole brain in patients affected by CM. Our aim was to investigate whether fluctuations in the GM volumes were related to the clinical features of CM. METHODS: Twenty untreated patients with CM without a past medical history of medication overuse underwent 3-Tesla MRI scans and were compared to a group of 20 healthy controls (HCs)...
December 8, 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/29321625/cerebellar-grey-matter-modifications-in-lower-limb-amputees-not-using-prosthesis
#4
Antonella Di Vita, Maddalena Boccia, Liana Palermo, Federico Nemmi, Marco Traballesi, Stefano Brunelli, Roberto De Giorgi, Gaspare Galati, Cecilia Guariglia
Plastic brain changes following peripheral deafferentation, in particular those following limb amputations, are well-documented, with significant reduction of grey matter (GM) in the sensory-motor cerebral areas representing the amputated limb. However, few studies have investigated the role played by the use of a prosthesis in these structural brain modifications. Here we hypothesized that using a functional prosthesis that allows individuals to perform actions may reduce grey matter reduction. We investigated the brain structural reorganization following lower limb amputation by using a Voxel Based Morphometry (VBM) analysis of structural magnetic resonance imaging (MRI) in 8 right-handed individuals with lower limb amputation (LLA) fitted with prostheses (LLAwp), compared to 6 LLA who had never used a prosthesis (LLAnp)...
January 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29320524/patients-with-primary-biliary-cholangitis-and-fatigue-present-with-depressive-symptoms-and-selected-cognitive-deficits-but-with-normal-attention-performance-and-brain-structure
#5
Roman Zenouzi, Janina von der Gablentz, Marcus Heldmann, Martin Göttlich, Christina Weiler-Normann, Marcial Sebode, Hanno Ehlken, Johannes Hartl, Anja Fellbrich, Susanne Siemonsen, Christoph Schramm, Thomas F Münte, Ansgar W Lohse
BACKGROUND: In primary biliary cholangitis (PBC) fatigue is a major clinical challenge of unknown etiology. By demonstrating that fatigue in PBC is associated with an impaired cognitive performance, previous studies have pointed out the possibility of brain abnormalities underlying fatigue in PBC. Whether structural brain changes are present in PBC patients with fatigue, however, is unclear. To evaluate the role of structural brain abnormalities in PBC patients severely affected from fatigue we, therefore, performed a case-control cerebral magnetic resonance imaging (cMRI) study and correlated changes of white and grey brain matter with the cognitive and attention performance...
2018: PloS One
https://www.readbyqxmd.com/read/29315984/default-mode-network-modifications-in-fabry-disease-a-resting-state-fmri-study-with-structural-correlations
#6
Sirio Cocozza, Giuseppe Pontillo, Mario Quarantelli, Francesco Saccà, Eleonora Riccio, Teresa Costabile, Gaia Olivo, Vincenzo Brescia Morra, Antonio Pisani, Arturo Brunetti, Enrico Tedeschi
Aim of the study was to evaluate the presence of Default Mode Network (DMN) modifications in Fabry Disease (FD), and their possible correlations with structural alterations and neuropsychological scores. Thirty-two FD patients with a genetically confirmed diagnosis of classical FD (12 males, mean age 43.3 ± 12.2) were enrolled, along with 35 healthy controls (HC) of comparable age and sex (14 males, mean age 42.1 ± 14.5). Resting-State fMRI data were analyzed using a seed-based approach, with six different seeds sampling the main hubs of the DMN...
January 9, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29302917/meta-analysis-of-voxel-based-morphometry-studies-of-gray-matter-abnormalities-in-patients-with-mesial-temporal-lobe-epilepsy-and-unilateral-hippocampal-sclerosis
#7
Liyun Zheng, Guo Bin, Hongwu Zeng, Dongfang Zou, Junling Gao, Jian Zhang, Bingsheng Huang
We aimed to perform a meta-analysis to systematically determine the most consistent regions of gray matter volume (GMV) abnormality in patients of unilateral mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS), and to reveal the difference of GMV abnormality between the patients with left-sided and right-sided MTLE-HS. A comprehensive and systematic search was performed in PubMed for voxel-based morphometry (VBM) studies of MTLE-HS. A total of 12 MTLE-HS studies, including 9 left-sided MTLE-HS (LMTLE-HS) and 8 right-sided MTLE-HS (RMTLE-HS) studies were included...
January 4, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29278717/heart-rate-variability-associated-with-grey-matter-volumes-in-striatal-and-limbic-structures-of-the-central-autonomic-network
#8
Luqing Wei, Hong Chen, Guo-Rong Wu
Previous neuroimaging studies have highlighted the functional neural correlates of cardiac vagal activity, providing convergent evidence that the cardiac vagal function is controlled by a number of brain regions in the central autonomic network (CAN). However, it remains largely unknown whether the underlying anatomicalbasis of those identified regions are associated with individual difference in vagal function. To address the above issue, this study used a large sample of healthy subjects (n=185) and voxel-based morphometry (VBM) analysis to verify brain morphometry associated with vagal control and the associations varied as a function of gender and age...
December 23, 2017: Brain Research
https://www.readbyqxmd.com/read/29275588/-impairments-of-gray-matter-in-mri-negative-epileptic-patients-with-different-seizure-types
#9
W Quan, Q Xu, F Yang, G H Chen, Z X Lin, Q R Zhang, J H Xiao, G M Lu, Z Q Zhang
Objective: To investigate the damage of gray matter structure in MRI-negative epilepsy patients with different symptoms by voxel-based morphometry (VBM). Methods: From June, 2009 to October, 2016, ninety MRI-negative epilepsy patients and thirty-five healthy volunteers underwent the 3T magnetic resonance imaging scan in Nanjing General Hospital. The patients were divided into three groups, including idiopathic generalized tonic-clonic seizure (I-GTCS), secondarily generalized tonic-clonic seizure (S-GTCS), and partial seizure (PS) according to different symptoms...
December 5, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29274735/neuroanatomical-heterogeneity-of-schizophrenia-revealed-by-semi-supervised-machine-learning-methods
#10
Nicolas Honnorat, Aoyan Dong, Eva Meisenzahl-Lechner, Nikolaos Koutsouleris, Christos Davatzikos
Schizophrenia is associated with heterogeneous clinical symptoms and neuroanatomical alterations. In this work, we aim to disentangle the patterns of neuroanatomical alterations underlying a heterogeneous population of patients using a semi-supervised clustering method. We apply this strategy to a cohort of patients with schizophrenia of varying extends of disease duration, and we describe the neuroanatomical, demographic and clinical characteristics of the subtypes discovered. METHODS: We analyze the neuroanatomical heterogeneity of 157 patients diagnosed with Schizophrenia, relative to a control population of 169 subjects, using a machine learning method called CHIMERA...
December 20, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/29274430/divergent-brain-changes-in-two-audiogenic-rat-strains-a-voxel-based-morphometry-and-diffusion-tensor-imaging-comparison-of-the-genetically-epilepsy-prone-rat-gepr-3-and-the-wistar-audiogenic-rat-war
#11
Yichien Lee, Olga C Rodriguez, Chris Albanese, Victor Rodrigues Santos, José Antônio Cortes de Oliveira, Ana Luiza Ferreira Donatti, Artur Fernandes, Norberto Garcia-Cairasco, Prosper N'Gouemo, Patrick A Forcelli
Acoustically evoked seizures (e.g., audiogenic seizures or AGS) are common in models of inherited epilepsy and occur in a variety of species including rat, mouse, and hamster. Two models that have been particularly well studied are the genetically epilepsy prone rat (GEPR-3) and the Wistar Audiogenic Rat (WAR) strains. Acute and repeated AGS, as well as comorbid conditions, displays a close phenotypic overlap in these models. Whether these similarities arise from convergent or divergent structural changes in the brain remains unknown...
December 20, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/29249960/behavioral-and-neuroimaging-evidence-for-facial-emotion-recognition-in-elderly-korean-adults-with-mild-cognitive-impairment-alzheimer-s-disease-and-frontotemporal-dementia
#12
Soowon Park, Taehoon Kim, Seong A Shin, Yu Kyeong Kim, Bo Kyung Sohn, Hyeon-Ju Park, Jung-Hae Youn, Jun-Young Lee
Background: Facial emotion recognition (FER) is impaired in individuals with frontotemporal dementia (FTD) and Alzheimer's disease (AD) when compared to healthy older adults. Since deficits in emotion recognition are closely related to caregiver burden or social interactions, researchers have fundamental interest in FER performance in patients with dementia. Purpose: The purpose of this study was to identify the performance profiles of six facial emotions (i.e., fear, anger, disgust, sadness, surprise, and happiness) and neutral faces measured among Korean healthy control (HCs), and those with mild cognitive impairment (MCI), AD, and FTD...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29247760/common-variation-in-znf804a-rs1344706-is-not-associated-with-brain-morphometry-in-schizophrenia-or-healthy-participants
#13
Yann Quidé, Natalie Matosin, Joshua R Atkins, Chantel Fitzsimmons, Murray J Cairns, Vaughan J Carr, Melissa J Green
BACKGROUND: The single nucleotide polymorphism (SNP) rs1344706 [A>C] within intron 2 of the zinc finger protein 804A gene (ZNF804A) is associated with schizophrenia at the genome-wide level, but its function in relation to the development of psychotic disorders, including its influence on brain morphology remains unclear. METHODS: Using both univariate (voxel-based morphometry, VBM; cortical thickness) and multivariate (source-based morphometry, SBM) approaches, we examined the effects of variation of the rs1344706 polymorphism on grey matter integrity in 214 Caucasian schizophrenia cases and 94 Caucasian healthy individuals selected from the Australian Schizophrenia Research Bank...
December 13, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29244889/elderly-patients-with-ongoing-migraine-show-reduced-gray-matter-volume-in-second-somatosensory-cortex
#14
Sébastien Celle, Christelle Créac'h, Claire Boutet, Frédéric Roche, Florian Chouchou, Jean-Claude Barthélémy, Roland Peyron
AIMS: To identify structural changes in gray matter in suspected migraine generators (the hypothalamus and/or brainstem nuclei) and pain pathways and to evaluate whether structural changes in migraine are definitive or resolve with age. METHODS: Voxel-based morphometry (VBM) was used to assess differences in gray matter between 39 healthy controls (HC), 25 episodic migraine (EM) subjects, and 37 subjects with a history of migraine (HM). In addition, morphometric changes were specifically investigated in suspected migraine generators and/or pain pathways...
December 15, 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29244231/differences-in-regional-grey-matter-volumes-in-currently-ill-patients-with-anorexia-nervosa
#15
Andrea Phillipou, Susan Lee Rossell, Caroline Gurvich, David Jonathan Castle, Larry Allen Abel, Richard Grant Nibbs, Matthew Edward Hughes
Neurobiological findings in anorexia nervosa (AN) are inconsistent, including differences in regional grey matter volumes. Methodological limitations often contribute to the inconsistencies reported. The aim of this study was to improve on these methodologies by utilising voxel based morphometry (VBM) analysis with the use of diffeomorphic anatomic registration through an exponentiated lie algebra algorithm (DARTEL), in a relatively large group of individuals with AN. Twenty-six individuals with AN and 27 healthy controls underwent a T1-weighted magnetic resonance imaging (MRI) scan...
December 15, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29241650/regional-gray-matter-volume-mediates-the-relationship-between-maternal-emotional-warmth-and-gratitude
#16
Junyi Yang, Dongtao Wei, Kangcheng Wang, Zili Yi, Jiang Qiu
Researchers have examined how parenting behavior influences individuals' brain structure and behavioral development, primarily among people who have experienced maltreatment. However, information relating to the anatomical structure associated with the parenting behavior in young healthy individuals who have not experienced maltreatment is scant. Gratitude is an important aspect of human sociality. Both the extent to which parenting behavior influences gratitude and the neural basis of the relationship between parenting behavior and gratitude are unclear...
December 11, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/29239055/brain-structural-alterations-associated-with-dysfunctional-cognitive-control-of-pain-in-patients-with-low-back-pain
#17
O Chehadi, A C Rusu, K Konietzny, E Schulz, O Köster, T Schmidt-Wilcke, M I Hasenbring
BACKGROUND: Recent evidence has shown that chronic back pain (CBP) can lead to functional alterations in the circuitry underlying the cognitive control of pain. Thought suppression (TS) is a common type of cognitive control of pain. Previous research has shown that TS has paradoxical effects that may increase the awareness of pain. Pain-related TS may also increase individuals' attention to pain, which may also increase pain sensation, but thus far, the relationship between pain-related TS and structural brain alterations is unknown...
December 14, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29234959/olfactory-cortex-and-olfactory-bulb-volume-alterations-in-patients-with-post-infectious-olfactory-loss
#18
Linyin Yao, Xiaoli Yi, Jayant Marian Pinto, Xiandao Yuan, Yichen Guo, Yifan Liu, Yongxiang Wei
Upper respiratory tract infection (URI) is one of the most common etiology of olfactory loss. Previous studies demonstrated that both olfactory bulb (OB) volume and sulcus (OS) depth decreased in patients with post-infectious olfactory loss (PIOL) compared to normal controls. The aim of our study was to observe alterations of central olfactory pathways in patients with PIOL. T1 weighted magnetic resonance images were acquired in 19 PIOL patients and 19 age- and sex-matched control subjects on a 3 T scanner...
December 13, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29234958/the-relationship-between-putamen-sma-functional-connectivity-and-sensorimotor-abnormality-in-esrd-patients
#19
Dun Ding, Peng Li, Xue-Ying Ma, Wang-Huan Dun, Shi-Feng Yang, Shao-Hui Ma, Hong-Juan Liu, Ming Zhang
The basal ganglia (BG) are composed of several nuclei involved in neural processing associated with integration of sensory and motor information. Recent neuroimaging studies implicated its key role in control of voluntary motor function. As the sensorimotor abnormality is common among the end-stage renal disease (ESRD) population, in the current study, we aimed to investigate the abnormal structure and functional connectivity patterns of BG in ESRD patients. Twenty-nine ESRD and twenty-nine age and gender-matched healthy controls (HC) were enrolled to compare the volume of the subsets in the BG (e...
December 12, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29232849/in-vitro-investigation-of-wear-of-cad-cam-polymeric-materials-against-primary-teeth
#20
Jae-Won Choi, Eun-Ju Song, Jong-Hyun Shin, Tae-Sung Jeong, Jung-Bo Huh
The aim of the study was to evaluate the effects of polymeric computer-aided design/computer-aided manufacturing CAD/CAM materials on antagonistic primary tooth wear. Five CAD/CAM polymeric materials were examined: Vipi Block Monocolor (VBM), Yamahachi polymethylmethacrylate (PMMA) (YAP), Mazic Duro (MZD), Vita Enamic (ENA), and Pekkton (PEK). All of the specimens were tested in a thermomechanical loading machine with the primary canine as the antagonist (50 N, 1.2 × 10⁵ cycles, 1.7 Hz, 5/55 °C). The wear losses of the antagonist tooth and the restorative materials were calculated using reverse modelling software and an electronic scale...
December 9, 2017: Materials
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