keyword
MENU ▼
Read by QxMD icon Read
search

VBM

keyword
https://www.readbyqxmd.com/read/28072384/impact-of-cerebellar-atrophy-on-cortical-gray-matter-and-cerebellar-peduncles-as-assessed-by-voxel-based-morphometry-and-high-angular-resolution-diffusion-imaging
#1
Michael Dayan, G Olivito, M Molinari, Mara Cercignani, Marco Bozzali, M Leggio
In recent years the cerebellum has been attributed amore important role in higher-level functions than previously believed. We examined a cohort of patients suffering from cerebellar atrophy resulting in ataxia, with two main objectives: first to investigate which regions of the cerebrum were affected by the cerebellar degeneration, and second to assess whether diffusion magnetic resonance imaging (dMRI) metrics within the medial (MCP) and superior cerebellar peduncle (SCP) - namely fractional anisotropy (FA) and radial diffusivity (RD) - could be used as a biomarker in patients with this condition...
October 2016: Functional Neurology
https://www.readbyqxmd.com/read/28070745/considering-total-intracranial-volume-and-other-nuisance-variables-in-brain-voxel-based-morphometry-in-idiopathic-pd
#2
Samuel Crowley, Haiqing Huang, Jared Tanner, Qing Zho, Nadine A Schwab, Loren Hizel, Daniel Ramon, Babette Brumback, Mingzhou Ding, Catherine C Price
Voxel-based morphometry (VBM) studies of Parkinson's disease (PD), have yielded mixed results, possibly due to several studies not accounting for common nuisance variables (age, sex, and total intracranial volume [TICV]). TICV is particularly important because there is evidence for larger TICV in PD. We explored the influence of these covariates on VBM by 1) comparing PD patients and controls before adding covariates, after adding age and sex, and after adding age, sex and TICV, and 2) by comparing controls split into large and small TICV before and after controlling for TICV, with age and sex accounted for in both analyses...
January 9, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28069530/structural-changes-in-functionally-illiterate-adults-after-intensive-training
#3
Melanie Boltzmann, Bahram Mohammadi, Amir Samii, Thomas F Münte, Jascha Rüsseler
About 7.5 million adults in Germany cannot read and write properly despite attending school for several years. They are considered to be functional illiterates. Since the ability to read and write is crucial for being employed and socially accepted, we developed a literacy training to overcome these deficits. In this study, we investigate the structural changes induced by the training. A group of 20 functional illiterates and 20 adult normal readers participated in the study. Group differences as well as intervention-related changes in gray (voxel-based morphometry, VBM) and white matter (tract-based spatial statistics, TBSS, applied to fractional anisotropy, FA, obtained with diffusion tensor imaging, DTI) were assessed in functional illiterates and normal reading controls...
January 6, 2017: Neuroscience
https://www.readbyqxmd.com/read/28060866/patterns-of-gray-matter-abnormalities-in-idiopathic-generalized-epilepsy-a-meta-analysis-of-voxel-based-morphology-studies
#4
Guo Bin, Tianfu Wang, Hongwu Zeng, Xiaoming He, Feng Li, Jian Zhang, Bingsheng Huang
OBJECTIVE: We aimed to identify the consistent regions of gray matter volume (GMV) abnormalities in idiopathic generalized epilepsy (IGE), and to study the difference of GMV abnormalities among IGE subsyndromes by applying activation likelihood estimation (ALE) meta-analysis. METHODS: A systematic review of VBM studies on GMV of patients with absence epilepsy (AE), juvenile myoclonic epilepsy (JME), IGE and controls indexed in PubMed and ScienceDirect from January 1999 to June 2016 was conducted...
2017: PloS One
https://www.readbyqxmd.com/read/28057431/advanced-structural-neuroimaging-in-progressive-supranuclear-palsy-where-do-we-stand
#5
REVIEW
Albert Stezin, Abhishek Lenka, Ketan Jhunjhunwala, Jitender Saini, Pramod K Pal
Progressive supranuclear palsy (PSP) is a progressive neurological disorder characterized by presence of supranuclear gaze palsy, early postural instability, parkinsonism and cognitive impairment. Advanced structural neuroimaging studies have demonstrated variable areas of grey and white matter involvement in PSP. Grey matter (GM) involvement is predominantly reported in the midbrain, subcortical structures such as thalamus and basal ganglia, and cerebellum. Most white matter (WM) tracts are also reported to be damaged in PSP...
December 26, 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28057397/neural-alterations-in-adhd-children-as-indicated-by-voxel-based-cortical-thickness-and-morphometry-analysis
#6
Uttam Kumar, Amit Arya, Vivek Agarwal
PURPOSE: Neuroimaging studies provide vital information related to the neurobiology of ADHD, but there still exists a wide gap in relevant information. The present study aimed to elucidate the neuroanatomical alteration in Attention deficit hyperactivity disorder (ADHD) children/adolescents. METHODS: Voxel-based cortical thickness (VBCT) and voxel-based morphometry (VBM) was performed to examine neuroanatomic distinctions in 18 children/adolescents aged 7.5-13years diagnosed with DSM-IV TR as ADHD (non-medicated)...
January 2, 2017: Brain & Development
https://www.readbyqxmd.com/read/28054057/second-order-nonlinear-optical-properties-of-bulk-gec-polytypes-g-gec-and-corresponding-nanotubes-first-principles-calculations
#7
Lei Hu, Dongshan Wei
Very recently, researchers have found that low-dimensional materials display more intriguing second-order nonlinear optical (NLO) phenomena and possess larger second-order NLO susceptibilities than the corresponding bulk forms. Here, we perform a systematic first-principles study of the second-order NLO properties and linear electro-optical coefficients of GeC bulk polytypes, g-GeC and corresponding nanotubes. Remarkably, the second-order NLO susceptibility χ((2)) of g-GeC and corresponding nanotubes can be comparable with that of the archetypical NLO semiconductor GaAs...
January 5, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28048182/su-g-iep1-14-the-relationship-between-voxel-based-morphometry-and-fiber-tract-abnormalities-by-correlation-analysis-in-patients-with-neurodegerative-disease
#8
R Juh, T Suh, J Han, C Kim, C Oh
PURPOSE: We evaluated the relationship between white matter (WM) tract disintegration and gray matter (GM) atrophy in patients with Alzheimer's disease (AD), mild cognitive impairment (MCI) and controls, using diffusion tensor imaging (DTI) and an optimized voxel-based analysis. METHODS: Two hundred thirty one individuals (61 controls, 116 MCI and 54 AD) were included. Voxel-based WM tract statistics was used to obtain whole-brain maps of WM bundles for FA. Voxel-based morphometry (VBM) was conducted to detect regions of gray matter (GM) atrophy in the AD, MCI group relative to the control group...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047588/su-f-i-20-volumetric-reduction-of-the-corpus-callosum-in-alzheimer-s-disease-and-mild-cognitive-impairment
#9
R Juh, T Suh, J Han, C Kim, C Oh
PURPOSE: This study investigated correlations between regional corpus callosum (CC) atrophy and cognitive measurements in AD subjects at mild disease stages with volumetry. Our aims were to replicate ROI-based findings of reduced volumes of the CC in mild cognitive impairment (MCI) patients relative to AD and to investigate, on a voxel-by-voxel basis, the presence of significant correlations between CC atrophy and cognitive test scores in AD subjects. METHODS: We used the VBM and cross-sectional ROI-based volumetry approach to conduct a detailed assessment of CC volumetric reductions in a probable AD patient (n=40) in comparison to MCI (n=40) and Subjective memory impairment (SMI) (n=12) matched for age...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045130/sex-related-difference-in-human-white-matter-volumes-studied-inspection-of-the-corpus-callosum-and-other-white-matter-by-vbm
#10
Akihiko Shiino, Yen-Wei Chen, Kenji Tanigaki, Atsushi Yamada, Piers Vigers, Toshiyuki Watanabe, Ikuo Tooyama, Ichiro Akiguchi
It has been contended that any observed difference of the corpus callosum (CC) size between men and women is not sex-related but brain-size-related. A recent report, however, showed that the midsagittal CC area was significantly larger in women in 37 brain-size-matched pairs of normal young adults. Since this constituted strong evidence of sexual dimorphism and was obtained from publicly available data in OASIS, we examined volume differences within the CC and in other white matter using voxel-based morphometry (VBM)...
January 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28035997/contribution-of-gray-and-white-matter-abnormalities-to-cognitive-impairment-in-multiple-sclerosis
#11
Xiaofei Zhang, Fangfang Zhang, Dehui Huang, Lei Wu, Lin Ma, Hua Liu, Yujun Zhao, Shengyuan Yu, Jiong Shi
Patients with multiple sclerosis (MS) commonly exhibit cognitive impairments (CI). However, the neural mechanisms underlying CI remain unclear. The current study applied diffusion tensor imaging (DTI) and voxel-based morphometric (VBM) magnetic resonance imaging (MRI) techniques to evaluate differences in white matter (WM) integrity and gray matter (GM) volume between MS patients with CI and MS patients with cognitive preservation (CP). Neuropsychological assessment and MRI were obtained from 39 relapsing-remitting MS (RRMS) patients and 29 healthy controls (HCs)...
December 27, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28028808/structural-gray-matter-alterations-in-chronic-migraine-implications-for-a-progressive-disease
#12
Lars Neeb, Kaili Bastian, Kersten Villringer, Heike Israel, Uwe Reuter, Jochen B Fiebach
OBJECTIVE: To identify possible gray matter alterations in patients with chronic migraine using voxel-based morphometry (VBM). BACKGROUND: VBM studies demonstrate structural alterations of gray matter (GM) in episodic migraine (EM) patients. Some of these alterations correlate with disease duration and headache frequency. We assessed GM alterations in chronic migraine (CM) and EM to evaluate the concept of migraine as a progressive disorder of the brain. METHODS: Individually age and sex-matched subjects with CM or EM (both without aura) and healthy controls (n = 21 per group) underwent magnetic resonance imaging-based VBM...
December 28, 2016: Headache
https://www.readbyqxmd.com/read/28018194/cross-sectional-and-longitudinal-relationships-between-depressive-symptoms-and-brain-atrophy-in-ms-patients
#13
Heiner Stuke, Katrin Hanken, Jochen Hirsch, Jan Klein, Fabian Wittig, Andreas Kastrup, Helmut Hildebrandt
Introduction: Depressive symptoms are a frequent and distressing phenomenon in Multiple Sclerosis (MS) patients. Cross-sectional research links these symptoms to reduced brain gray matter volumes in parts of the prefrontal and temporal lobe as well as subcortical structures like the hippocampus, nucleus caudatus and globus pallidus. Nevertheless, prospective relationships between regional gray matter volume and the course of depressive symptoms are poorly understood. Methods: Forty-four patients with relapsing-remitting or secondary progressive MS participated in a prospective study with two assessments of depressive symptoms and high-resolution MRI with an inter-test-interval of 17 months...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28008201/active-brain-changes-after-initiating-fingolimod-therapy-in-multiple-sclerosis-patients-using-individual-voxel-based-analyses-for-diffusion-tensor-imaging
#14
Joe Senda, Hirohisa Watanabe, Kuniyuki Endo, Keizo Yasui, Yasuhiro Hawsegawa, Noritaka Yoneyama, Takashi Tsuboi, Kazuhiro Hara, Mizuki Ito, Naoki Atsuta, Bagarinao Epifanio, Masahisa Katsuno, Shinji Naganawa, Gen Sobue
Voxel-based analysis (VBA) of diffusion tensor images (DTI) and voxel-based morphometry (VBM) in patients with multiple sclerosis (MS) can sensitively detect occult tissue damage that underlies pathological changes in the brain. In the present study, both at the start of fingolimod and post-four months clinical remission, we assessed four patients with MS who were evaluated with VBA of DTI, VBM, and fluid-attenuated inversion recovery (FLAIR). DTI images for all four patients showed widespread areas of increased mean diffusivity (MD) and decreased fractional anisotropy (FA) that were beyond the high-intensity signal areas across images...
December 2016: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/28005183/altered-gray-matter-volume-in-stable-chronic-obstructive-pulmonary-disease-with-subclinical-cognitive-impairment-an-exploratory-study
#15
Chunrong Wang, Yanhui Ding, Bixian Shen, Dehong Gao, Jie An, Kewen Peng, Gangqiang Hou, Liqiu Zou, Mei Jiang, Shijun Qiu
Gray matter volume deficits have been identified in cognitively impaired patients with chronic obstructive pulmonary disease (COPD). However, it remains unknown whether the gray matter volume is altered in COPD patients with subclinical cognitive impairment. To determine whether any gray matter abnormalities are present in these patients, neuropsychological tests and structural MRI data were analyzed from 60 patients with COPD and 60 age-, gender-, education-, and handedness-matched normal controls (NCs). The COPD patients had similar Mini-Mental State Examination (MMSE) scores compared with the NCs...
December 22, 2016: Neurotoxicity Research
https://www.readbyqxmd.com/read/27994534/influence-of-group-on-individual-subject-maps-in-spm-voxel-based-morphometry
#16
Andrew M Michael, Eli Evans, Gregory J Moore
Voxel based morphometry (VBM) is a widely utilized neuroimaging technique for spatially normalizing brain structural MRI (sMRI) onto a common template. The DARTEL technique of VBM takes into account the spatial intensity distribution of sMRIs to construct a study specific group template. The group template is then used to create final individual normalized tissue maps (FINTM) for each subject in the group. In this study, we investigate the effect of group on FINTM, i.e., we evaluate the variability of a constant subject's FINTM when other subjects in the group are iteratively changed...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27994367/brainstem-dysfunction-in-patients-with-late-onset-lennox-gastaut-syndrome-voxel-based-morphometry-and-tract-based-spatial-statistics-study
#17
Kang Min Park, Yun Jung Hur, Sung Eun Kim
BACKGROUND: There have been a few reports of patients who developed Lennox-Gastaut syndrome (LGS) in the second decades of their life. OBJECTIVES: The aim of this study was to investigate electroclinical presentation in patients with late-onset LGS. In addition, we evaluated structural abnormalities of the brain, which may give some clue about the common pathogenic pathway in LGS. MATERIALS AND METHODS: We enrolled the patients with late-onset LGS...
October 2016: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/27989500/gray-matter-abnormalities-associated-with-fibromyalgia-a-meta-analysis-of-voxel-based-morphometric-studies
#18
HaiCun Shi, CongHu Yuan, ZhenYu Dai, HaiRong Ma, LiQin Sheng
OBJECTIVES: Studies employing voxel-based morphometry (VBM) have reported inconsistent findings on the association of gray matter (GM) abnormalities with fibromyalgia. The aim of the present study is to identify the most prominent and replicable GM areas that involved in fibromyalgia. METHODS: A systematic search of the PubMed database from January 2000 to September 2015 was performed to identify eligible whole-brain VBM studies. Comprehensive meta-analyses to investigate regional GM abnormalities in fibromyalgia were conducted with the Seed-based d Mapping software package...
December 2016: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/27986606/imaging-the-neuroplastic-effects-of-ketamine-with-vbm-and-the-necessity-of-placebo-control
#19
A Höflich, S Ganger, M Tik, A Hahn, G S Kranz, T Vanicek, M Spies, C Kraus, C Windischberger, S Kasper, D Winkler, R Lanzenberger
In the last years a plethora of studies have investigated morphological changes induced by behavioural or pharmacological interventions using structural T1-weighted MRI and voxel-based morphometry (VBM). Ketamine is thought to exert its antidepressant action by restoring neuroplasticity. In order to test for acute impact of a single ketamine infusion on grey matter volume we performed a placebo-controlled, double-blind investigation in healthy volunteers using VBM. 28 healthy individuals underwent two MRI sessions within a timeframe of 2 weeks, each consisting of two structural T1-weighted MRIs within a single session, one before and one 45min after infusion of S-ketamine (bolus of 0...
December 13, 2016: NeuroImage
https://www.readbyqxmd.com/read/27942451/neuroanatomical-correlates-of-prion-disease-progression-a-3t-longitudinal-voxel-based-morphometry-study
#20
Enrico De Vita, Gerard R Ridgway, Mark J White, Marie-Claire Porter, Diana Caine, Peter Rudge, John Collinge, Tarek A Yousry, Hans Rolf Jager, Simon Mead, John S Thornton, Harpreet Hyare
PURPOSE: MRI has become an essential tool for prion disease diagnosis. However there exist only a few serial MRI studies of prion patients, and these mostly used whole brain summary measures or region of interest based approaches. We present here the first longitudinal voxel-based morphometry (VBM) study in prion disease. The aim of this study was to systematically characterise progressive atrophy in patients with prion disease and identify whether atrophy in specific brain structures correlates with clinical assessment...
2017: NeuroImage: Clinical
keyword
keyword
83596
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"