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https://www.readbyqxmd.com/read/29466975/the-impact-of-alcohol-among-injury-patients-in-moshi-tanzania-a-nested-case-crossover-study
#1
Catherine A Staton, Joao Ricardo Nickenig Vissoci, Nicole Toomey, Jihad Abdelgadir, Patricia Chou, Michael Haglund, Blandina T Mmbaga, Mark Mvungi, Monica Swahn
BACKGROUND: Globally, alcohol is responsible for 3.3 million deaths annually and contributes to 5.9% of the overall global burden of disease. In Sub-Saharan Africa, alcohol is the leading avoidable risk factor accounting for a substantial portion of death and disability. This project aimed to determine the proportion of injuries related to alcohol and the increased risk of injury due to alcohol among injury patients seeking care at the emergency department (ED) of Kilimanjaro Christian Medical Centre (KCMC) in Moshi, Tanzania...
February 21, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29466949/the-association-between-pre-pregnancy-body-mass-index-and-risk-of-preeclampsia-a-registry-based-study-from-tanzania
#2
Dorah Mrema, Rolv Terje Lie, Truls Østbye, Michael Johnson Mahande, Anne Kjersti Daltveit
BACKGROUND: Preeclampsia is among the leading causes of maternal mortality and morbidity worldwide, occurs in 2-8% of all pregnancies, and is estimated to account for at least 9 % of maternal deaths in Africa. Studies from developed countries show that high pre pregnancy body mass index (BMI) increases the risk of preeclampsia. We examined the association between pre pregnancy BMI and the risk of preeclampsia in Tanzania, a low income country. METHODS: Data from the Kilimanjaro Christian Medical Center (KCMC) Medical Birth Registry recorded between July 2000 and May 2013 were used...
February 21, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29464424/prevalence-and-risk-factors-for-ctx-m-gram-negative-bacteria-in-hospitalized-patients-at-a-tertiary-care-hospital-in-kilimanjaro-tanzania
#3
Tolbert Sonda, Happiness Kumburu, Marco van Zwetselaar, Michael Alifrangis, Blandina T Mmbaga, Ole Lund, Frank M Aarestrup, Gibson Kibiki
Emergence and spread of extended spectrum beta-lactamase (ESBL)-producing gram-negative bacteria, mainly due to CTX-M, is a major global public health problem. Patients infected with ESBL-producing gram-negative bacteria have an increased risk of treatment failure and death. We investigated the prevalence and risk factors for CTX-M gram-negative bacteria isolated from clinical specimens of patients hospitalized at a tertiary care hospital in Kilimanjaro, Tanzania. Isolated gram-negative bacteria from inpatients admitted at Kilimanjaro Christian Medical Centre (KCMC) between August 2013 and August 2015 were fully genome sequenced...
May 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29220120/efavirenz-is-related-to-neuropsychiatric-symptoms-among-adults-but-not-among-adolescents-living-with-human-immunodeficiency-virus-in-kilimanjaro-tanzania
#4
Marion Sumari-de Boer, Arnt Schellekens, Ashanti Duinmaijer, Julieth M Lalashowi, Happiness J Swai, Quirijn de Mast, Andre van der Ven, Grace Kinabo
OBJECTIVES: To explore the relationship between Efavirenz (EFV) and neuropsychiatric symptoms among adults and adolescents living with human immunodeficiency virus (HIV) in Kilimanjaro, Tanzania. METHODS: Cross-sectional study among HIV-infected adults (age 18-65) and adolescents (age 12-17) on antiretroviral treatment attending Kilimanjaro Christian Medical Centre, Moshi, Tanzania. Neuropsychiatric symptoms were measured using the Hospital Anxiety and Depression Scale (HADS), the Symptom Checklist 90 (SCL-90) and the Mini-International Neuropsychiatric Interview (MINI)...
February 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29178236/prevalence-predictors-and-challenges-of-gestational-diabetes-mellitus-screening-among-pregnant-women-in-northern-tanzania
#5
H I Njete, B John, P Mlay, M J Mahande, S E Msuya
OBJECTIVES: To determine the prevalence and predictors of gestational diabetes mellitus (GDM) as well as acceptability of returning for glucose tolerance testing among pregnant women in Moshi municipality, northern Tanzania. METHODS: Cross-sectional study from October 2015 to April 2016 among women with gestation age of 24-28 weeks of pregnancy attending at Kilimanjaro Christian Medical Centre (KCMC) referral hospital, Majengo and Pasua Health Centres. Women were interviewed and requested to return the next day (window within a month, depending on gestational age) for fasting plasma glucose (FPG) testing, followed immediately by a 75 g oral glucose tolerance test (OGTT)...
February 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28813528/maternal-and-fetal-risk-factors-for-stillbirth-in-northern-tanzania-a-registry-based-retrospective-cohort-study
#6
Francisca S Chuwa, Amasha H Mwanamsangu, Benjamin G Brown, Sia E Msuya, Elizabeth E Senkoro, Oresta P Mnali, Festo Mazuguni, Michael J Mahande
BACKGROUND: Stillbirth is a major cause of perinatal mortality and occurs disproportionately in developing countries including Tanzania. However, there is scant information regarding the predictors of this condition in Tanzania. This study aimed to determine maternal and fetal risk factors for stilbirth in northen Tanzania. METHODOLOGY: A retrospective cohort study was performed using maternally-linked data from the Kilimanjaro Christian Medical Centre birth registry...
2017: PloS One
https://www.readbyqxmd.com/read/28797181/hiv-resistance-and-prevention-of-mother-to-child-transmission-regimen-in-hiv-infected-infants-in-northern-tanzania
#7
Dorothy E Dow, Werner Schimana, Balthazar M Nyombi, Blandina T Mmbaga, Aisa M Shayo, John A Bartlett, Charles G Massambu, Emmanuel G Kifaro, Elizabeth L Turner, Todd DeMarco, Fangping Cai, Coleen K Cunningham, Ann M Buchanan
Prevention of mother-to-child transmission (PMTCT) guidelines recommend that all HIV-infected pregnant women receive antiretroviral therapy (Option B) and HIV-infected infants should initiate therapy with a protease inhibitor-based regimen; however, implementation of these guidelines has lagged in many resource-limited settings. Tanzania only recently implemented these guidelines with little country-specific data to inform whether HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) resistance was present among infected infants under the Option A guidelines...
November 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28545428/prevalence-severity-and-early-outcomes-of-hypoxic-ischemic-encephalopathy-among-newborns-at-a-tertiary-hospital-in-northern-tanzania
#8
Irene N Simiyu, Deborah N Mchaile, Kahindo Katsongeri, Rune N Philemon, Sia E Msuya
BACKGROUND: Hypoxic Ischemic Encephalopathy (HIE) remains a problem of great concern worldwide especially in developing countries. The occurrence of a neurological syndrome can be an indicator of insult to the brain. We aimed to determine the prevalence, HIE proportions, neurological signs and early outcomes of newborns that developed birth asphyxia at KCMC Tanzania. METHODS: A prospective study was conducted at KCMC from November 2014 to April 2015 among newborns with birth asphyxia...
May 25, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28503327/the-characteristics-of-traumatic-spinal-cord-injuries-at-a-referral-hospital-in-northern-tanzania
#9
Sakina Mehboob Rashid, Mubashir Alavi Jusabani, Faiton Ndesanjo Mandari, Marieke Cornelia Johanna Dekker
STUDY DESIGN: Retrospective study. OBJECTIVES: To describe the epidemiology of traumatic spinal cord injury (TSCI) in Northern Tanzania. SETTING: Main referral hospital for Northern Tanzania. METHODS: A retrospective review of 125 TSCI cases admitted to Kilimanjaro Christian Medical Centre (KCMC) over a period of 5 years. RESULTS: We included 125 patients in the sample size, with a male majority of 107 (85...
2017: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/28484993/hip-fracture-pattern-at-a-major-tanzanian-referral-hospital-focus-on-fragility-hip-fractures
#10
Munyaradzi Tsabasvi, Sonya Davey, Rogers Temu
This study examined hip fractures during a 5-year period at Kilimanjaro Christian Medical Center (KCMC). There was a general increase in proportions of fragility hip fractures during this period. PURPOSE: Fragility hip fractures are expected to increase in low-resource countries. This study examined hip fractures in the osteoporotic age group during a 5-year period at the Kilimanjaro Christian Medical Center (KCMC), which is located in Moshi, Tanzania. METHODS: We conducted a retrospective study of all hip fracture patients above the age of 50 who were admitted to KCMC between January 1, 2011 and December 31, 2015...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/27347296/an-examination-of-inpatient-medical-record-keeping-in-the-orthopaedic-department-of-kilimanjaro-christian-medical-centre-kcmc-moshi-tanzania
#11
Alexander Conor Hollis, Samuel Robert Ebbs
INTRODUCTION: There is a lack of published evidence examining the quality of patient notes in African healthcare settings. We aim to examine the completeness of the orthopaedic inpatient notes and begin development of a formal audit framework in a large Tanzanian Hospital. METHODS: A retrospective review of 155 orthopaedic inpatient notes at Kilimanjaro Christian Medical Centre (KCMC) was conducted spanning 3 months. Notes were reviewed using an agreed data collection pro forma considering 3 main outcomes; i) quantity of complete entries, ii) percentage completeness of individual sections, iii) documentation of follow-up...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27268015/effect-of-interpregnancy-interval-on-adverse-pregnancy-outcomes-in-northern-tanzania-a-registry-based-retrospective-cohort-study
#12
Michael J Mahande, Joseph Obure
BACKGROUND: Both short and long interpregnancy intervals have been associated with an increased risk of adverse pregnancy outcomes. There is limited information about the impact of interpregnancy interval on pregnancy (IPI) outcomes in Tanzania. The objective of this study was to assess the effect of IPI on adverse pregnancy outcomes. METHODS: We performed a retrospective cohort study using maternally-linked data from Kilimanjaro Christian Medical Centre (KCMC) birth registry...
June 7, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27195602/providing-safe-and-effective-preventative-antiretroviral-prophylaxis-to-hiv-exposed-newborns-via-a-novel-drug-delivery-system-in-tanzania
#13
Alexander P Dahinten, Dorothy E Dow, Coleen K Cunningham, Levina J Msuya, Blandina T Mmbaga, Robert A Malkin
BACKGROUND: In developing countries, antiretroviral therapy provides life-saving treatment to HIV-positive women and their children before, during and after birth. However, supply chain challenges such as long distances, medication shortages and nonfacility deliveries often compromise consistent access to prophylactic treatment for at-risk infants. A proposed intervention to address these challenges, often referred to as the "Pratt Pouch," allows for liquid-formulation medications, such as nevirapine (NVP), to be repackaged into single-dose pouches...
September 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/26874788/prevalence-of-parasitic-infections-and-associations-with-pregnancy-complications-and-outcomes-in-northern-tanzania-a-registry-based-cross-sectional-study
#14
Aneth Mkunde Mahande, Michael Johnson Mahande
BACKGROUND: Parasitic infection(s) during pregnancy have been associated with increased risk of pregnancy complications and adverse outcomes in low resource settings. However, little is known about their influence on pregnancy outcomes. This study aimed to determine the prevalence of parasitic infections and their association with pregnancy complications and adverse outcomes. METHODS: A retrospective cross-sectional study was conducted using maternally-linked data from Kilimanjaro Christian Medical Center (KCMC) medical birth registry...
February 13, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/26446879/frequency-risk-factors-and-feto-maternal-outcomes-of-abruptio-placentae-in-northern-tanzania-a-registry-based-retrospective-cohort-study
#15
Godwin S Macheku, Rune Nathaniel Philemon, Olola Oneko, Pendo S Mlay, Gileard Masenga, Joseph Obure, Michael Johnson Mahande
BACKGROUND: Abruptio placentae remains a major cause of maternal and perinatal morbidity and mortality in developing countries. Little is known about the burden of abruptio placentae in Tanzania. This study aimed to determine frequency, risk factors for abruptio placentae and subsequent feto-maternal outcomes in women with abruptio placentae. METHODS: We designed a retrospective cohort study using maternally-linked data from Kilimanjaro Christian Medical Centre (KCMC) medical birth registry...
October 7, 2015: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/26337194/alcohol-consumption-among-pregnant-women-in-northern-tanzania-2000-2010-a-registry-based-study
#16
Alexander Blaauw Isaksen, Truls Østbye, Blandina Theophil Mmbaga, Anne Kjersti Daltveit
BACKGROUND: Alcohol can be harmful to the development of the foetus. In most developed countries, pregnant women are recommended to abstain from alcohol, however in developing countries, women are less likely to receive these recommendations. With respect to pregnant women in Northern Tanzania, this study aims to 1) describe time trends in level of alcohol consumption, 2) assess socio-demographic predictors of alcohol consumption, and 3) describe associations between alcohol consumption and health-related maternal and foetal outcomes...
2015: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/26161174/prevalence-of-persistent-microalbuminuria-and-associated-factors-among-hiv-infected-children-attending-a-tertiary-hospital-in-northern-tanzania-a-cross-sectional-analytical-study
#17
Ignatus Kissima Mosten, Bernadus Carolus Hamel, Grace Damas Kinabo
INTRODUCTION: Human Immunodeficiency Virus (HIV) infection is a significant cause of paediatric morbidity and mortality especially in Sub-Saharan Africa. It affects the kidney by injuring the glomerular and tubular epithelial cells causing leakage of albumin in urine. Microalbuminuria is known to be an early indicator of kidney injury including HIVAN. The purpose of this study was to identify the prevalence and factors associated with microalbuminuria among HIV infected children receiving care and treatment at Kilimanjaro Christian Medical Centre (KCMC)...
2015: Pan African Medical Journal
https://www.readbyqxmd.com/read/26069217/glaucoma-awareness-and-access-to-healthcare-perceptions-among-glaucoma-patients-in-tanzania
#18
Jeremy A Gilmour-White, Peter Shah, Vinette Cross, William Makupa, Heiko Philippin
OBJECTIVE: To investigate the barriers to access to eye health services for patients with glaucoma in Tanzania with the aim of identifying key areas for improvement and further research. DESIGN: Qualitative investigation using face-to-face semi-structured interviews with patients recruited from the Kilimanjaro Christian Medical Centre (KCMC) outpatient eye clinic. This project is part of the international strategy of the Research into Glaucoma and Ethnicity (ReGAE) programme...
July 2015: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/25745527/risks-precipitants-and-clinical-presentation-of-gastro-oesophageal-reflux-disease-at-the-kilimanjaro-christian-medical-centre-in-tanzania-corrected
#19
Michael Bartholomew Mwandri, Julius Chacha Mwita, Mgaywa Gilbert Mjungu Damas Magafu, Magafu Mgwaya, Kajiru Gad Kilonzo, Sarah Japhet Urasa, Sarah Urasa
INTRODUCTION: Risk factors and precipitants of gastro-oesophageal disease (GERD) differ widely in communities. We conducted an observational study to describe these risks, precipitants and clinical presentation of GERD patients at Kilimanjaro Christian Medical Centre (KCMC) in Tanzania. METHODS: We consecutively recruited 92 GERD patients who were referred for endoscopy at KCMC from March to November 2008. Using structured questionnaire risk factors, precipitants and symptoms of GERD were enquired...
2014: Pan African Medical Journal
https://www.readbyqxmd.com/read/25368739/factors-associated-with-hiv-status-disclosure-to-hiv-infected-children-receiving-care-at-kilimanjaro-christian-medical-centre-in-moshi-tanzania
#20
Livin Peter Mumburi, Bernardus Carolus Hamel, Rune Nathanael Philemon, Gibson Nsokolo Kapanda, Levina January Msuya
INTRODUCTION: With the introduction of antiretroviral drugs HIV-infected children live longer. Disclosure of HIV diagnosis is increasingly an important and inevitable issue. Both healthcare providers and caregivers face challenges of disclosure to children. The objective of the study was to explore factors associated with HIV-status disclosure to HIV-infected children receiving care at Kilimanjaro Christian Medical Centre (KCMC). METHODS: A cross-sectional hospital-based study was conducted from October 2011 to April 2012...
2014: Pan African Medical Journal
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