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https://www.readbyqxmd.com/read/29336245/the-role-of-colchicine-in-pericardial-syndromes
#1
George Lazaros, Massimo Imazio, Antonio Brucato, Charalambos Vlachopoulos, Emilia Lazarou, Dimitrios Vassilopoulos, Dimitris Tousoulis
BACKGROUND: Colchicine is an old drug originally employed for the treatment of inflammatory disorders such as acute gout and familiar Mediterranean fever. METHODS: In the past few decades, colchicine has been at the forefront of the pharmacotherapy of several cardiac diseases, including acute and recurrent pericarditis, coronary artery disease, prevention of atrial fibrillation and heart failure. In this review, we have summarized the current evidence based medicine and guidelines recommendations in the specific context of pericardial syndromes...
January 15, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29334933/temporary-exclusion-of-ill-children-from-childcare-centres-in-switzerland-practice-problems-and-potential-solutions
#2
Benjamin Sticher, Julia Bielicki, Christoph Berger
BACKGROUND: In childcare centres, temporary exclusion of ill children, if their illness poses a risk of spread of harmful diseases to others, is a central approach to fight disease transmission. However, not all ill children need to be excluded. Previous studies suggested that childcare centre staff have difficulties in deciding whether or not to exclude an ill child, even when official ill-child guidelines are used. We aimed to describe, quantify and analyse these ambiguities and discuss potential solutions...
January 15, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29334532/cost-effectiveness-and-improved-parent-and-provider-satisfaction-with-outpatient-management-of-pediatric-oncology-patients-with-low-risk-fever-and-neutropenia
#3
Abhishek Bavle, Amanda Grimes, Sibo Zhao, Daniel Zinn, Andrea Jackson, Binita Patel, Timothy Porea, Ankhi Dutta, Heidi Russell, Andras Heczey
On the basis of significant evidence for safety, the international pediatric fever and neutropenia committee recommends the identification and management of patients with "low-risk fever and neutropenia" (LRFN), outpatient with oral antibiotics, instead of traditional inpatient management. The aim of our study was to compare the cost-per-patient with these 2 strategies, and to evaluate parent and provider satisfaction with the outpatient management of LRFN. Between March 2016 and February 2017, 17 LRFN patients (median absolute neutrophil count, 90/μL) were managed at a single institution, per new guidelines...
January 12, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29330009/the-almanach-project-preliminary-results-and-potentiality-from-afghanistan
#4
A Bernasconi, F Crabbé, R Rossi, I Qani, A Vanobberghen, M Raab, S Du Mortier
INTRODUCTION: ALMANACH (ALgorithms for the MANagement of Acute CHildhood illnesses) is an electronic version of IMCI (Integrated Management of Childhood Illness) running on tablets. ALMANACH enhances its concept, it integrates well into health staff's daily consultation work and facilitates diagnosis and treatment. ALMANACH informs when to refer a child or to perform a rapid diagnostic test (RDT), recommends the right treatment dosage and synchronizes collected data real time with a Health Management Information System (DHIS2) for epidemiological evaluation and decision making...
December 28, 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29322059/citrus-seed-oils-efficacy-against-larvae-of-aedes-aegypti
#5
Hazrat Bilal, Waseem Akram, Soaib Ali Hassan, Sadrud Din
Background: Dengue fever is a serious public health issue in Pakistan for many years. Globally plants have been reported to contain compounds with insecticidal properties. These properties have been demonstrated more recently on the larval stages of mosquitoes. Therefore, Citrus cultivar seeds were evaluated for larvicidal potential against the primary dengue vector Aedes aegypti. Methods: Extraction of oil was done by a steam distillation method and oils were evaluated according to WHO guidelines for larvicides 2005 for evaluation of insecticidal properties of citrus seed extracts against mosquito larvae...
September 2017: Journal of Arthropod-borne Diseases
https://www.readbyqxmd.com/read/29319894/antibiotic-prescribing-for-endodontic-therapies-a-comparative-survey-between-general-dental-practitioners-gdps-and-final-year-bachelor-of-dental-surgery-bds-students-in-cardiff-uk
#6
A A Al Masan, P M H Dummer, D J J Farnell, M E Vianna
AIM: To evaluate the views of final-year dental surgery (BDS; G1) students at Cardiff University and general dental practitioners (GDPs; G2) within the city of Cardiff, Wales on antibiotic prescribing for endodontic conditions, and investigate the potential differences between the two groups. METHODS: A cross-sectional online questionnaire-based survey of 12 qualitative and quantitative questions was distributed to 76 final-year BDS Cardiff University students and 55 dental practices within Cardiff, UK...
January 10, 2018: International Endodontic Journal
https://www.readbyqxmd.com/read/29319209/effectiveness-of-antibacterial-prophylaxis-during-induction-chemotherapy-in-children-with-acute-lymphoblastic-leukemia
#7
M L Sulis, T M Blonquist, K E Stevenson, S K Hunt, S Kay-Green, U H Athale, L A Clavell, P D Cole, K M Kelly, C Laverdiere, J M Leclerc, B Michon, M A Schorin, J G Welch, D S Neuberg, S E Sallan, L B Silverman
BACKGROUND: Pediatric patients receiving induction chemotherapy for newly diagnosed acute lymphoblastic leukemia (ALL) are at high risk of developing life-threatening infections. We investigated whether uniform antibacterial guidelines, including mandatory antibacterial prophylaxis in afebrile patients during induction, decreases the incidence of microbiologically documented bacteremia. METHODS: Between 2012 and 2015, 230 patients with newly diagnosed ALL (aged 1-21) were enrolled on Dana-Farber Cancer Institute ALL Consortium Protocol 11-001 (DFCI 11-001)...
January 10, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29287595/dealing-with-chronic-non-bacterial-osteomyelitis-a-practical-approach
#8
REVIEW
Andrea Taddio, Giovanna Ferrara, Antonella Insalaco, Manuela Pardeo, Massimo Gregori, Martina Finetti, Serena Pastore, Alberto Tommasini, Alessandro Ventura, Marco Gattorno
BACKGROUND: Chronic Non-Bacterial Osteomyelitis (CNO) is an inflammatory disorder that primarily affects children. Although underestimated, its incidence is rare. For these reasons, no diagnostic and no therapeutic guidelines exist. The manuscript wants to give some suggestions on how to deal with these patients in the every-day clinical practice. MAIN BODY: CNO is characterized by insidious onset of bone pain with local swelling. Systemic symptoms such as fever, skin involvement and arthritis may be sometimes present...
December 29, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/29285572/characteristics-and-diagnoses-of-acute-headache-in-pregnant-women-a-retrospective-cross-sectional-study
#9
Bianca Raffaelli, Eberhard Siebert, Jeannette Körner, Thomas Liman, Uwe Reuter, Lars Neeb
BACKGROUND: Acute headache is one of the most frequent neurological symptoms in pregnant women. The early diagnosis of underlying secondary conditions has a major influence on patient outcome, especially in emergency settings. However, at the time being no well-established guideline for diagnostic evaluation of acute headache during pregnancy exists. In this study, we aimed to characterize acute headache in pregnant women concerning demographic, clinical, and diagnostic features, and to determine predictors of secondary headache...
December 4, 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/29280423/anemia-was-an-uncommon-complication-of-severe-malaria-in-a-high-transmission-rural-area-of-western-uganda
#10
Ross Boyce, Raquel Reyes, Corinna Keeler, Michael Matte, Moses Ntaro, Edgar Mulogo, Mark J Siedner
The clinical epidemiology of severe malaria among patients presenting to peripheral health centers has not been well described. We conducted a prospective, observational cohort study to describe the epidemiology and clinical manifestations of severe malaria in a highland area of declining transmission intensity in Western Uganda. Individuals presenting with a history of fever were screened with a malaria rapid diagnostic test (RDT). We prepared blood smears and conducted clinical and laboratory testing for those with a positive RDT...
December 26, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29279320/uk-role-4-military-infectious-diseases-and-tropical-medicine-cases-in-2005-2013
#11
Daniel S Burns, M R Riley, A Mason, M S Bailey
INTRODUCTION: Infectious diseases are a frequent cause of morbidity among British troops. The aim of this paper is to describe the spectrum of infectious diseases seen when UK service personnel are evacuated for definitive care to the Role 4 Medical Treatment Facility based at Birmingham Heartlands Hospital. METHOD: A retrospective analysis of all military patients presenting with infectious diseases and treated at Birmingham Heartlands Hospital between 14 April 2005 and 31 December 2013 was undertaken...
December 25, 2017: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29273539/effectiveness-of-who-s-pragmatic-screening-algorithm-for-child-contacts-of-tuberculosis-cases-in-resource-constrained-settings-a-prospective-cohort-study-in-uganda
#12
Leonardo Martinez, Ye Shen, Andreas Handel, Srijita Chakraburty, Catherine M Stein, LaShaunda L Malone, W Henry Boom, Frederick D Quinn, Moses L Joloba, Christopher C Whalen, Sarah Zalwango
BACKGROUND: Tuberculosis is a leading cause of global childhood mortality; however, interventions to detect undiagnosed tuberculosis in children are underused. Child contact tracing has been widely recommended but poorly implemented in resource-constrained settings. WHO has proposed a pragmatic screening approach for managing child contacts. We assessed the effectiveness of this screening approach and alternative symptom-based algorithms in identifying secondary tuberculosis in a prospectively followed cohort of Ugandan child contacts...
December 19, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/29237494/adherence-to-the-integrated-management-of-childhood-illness-guidelines-in-namibia-kenya-tanzania-and-uganda-evidence-from-the-national-service-provision-assessment-surveys
#13
Carsten Krüger, Monika Heinzel-Gutenbrunner, Mohammed Ali
BACKGROUND: Integrated Management of Childhood Illness (IMCI) is regarded as a standard public health approach to lowering child mortality in developing countries. However, little is known about how health workers adhere to the guidelines at the national level in sub-Saharan African countries. METHODS: Data from the Service Provision Assessment surveys of Namibia (NA) (survey year: 2009), Kenya (KE) (2010), Tanzania (TZ) (2006) and Uganda (UG) (2007) were analysed for adherence to the IMCI guidelines by health workers...
December 13, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29227420/us-state-public-health-departments-special-pathogen-planning
#14
Jocelyn J Herstein, Paul D Biddinger, Shawn G Gibbs, Aurora B Le, Katelyn C Jelden, Angela L Hewlett, John J Lowe
CONTEXT: US state public health departments played key roles in planning for and responding to confirmed and suspected cases of Ebola virus disease (EVD) during the 2014-2016 outbreak, including designating select hospitals as high-level isolation units (HLIUs) for EVD treatment in conjunction with the Centers for Disease Control and Prevention. OBJECTIVE: To identify existing guidelines and perspectives of state health departments pertaining to the management and transport of patients with EVD and other highly hazardous communicable diseases (HHCDs)...
December 7, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/29225757/dengue-fever-in-a-south-asian-metropolis-a-report-on-219-cases
#15
Shiv Sekhar Chatterjee, Ankush Sharma, Shilpee Choudhury, Sushil Kumar Chumber, Ras Bage, Nittin Parkhe, Uma Khanduri
Background and Objectives: Yearly epidemics of Dengue fever occur post-monsoon in India's capital, Delhi. A prospective observational study was conducted during the outbreak months to understand the epidemiology and outcome of this infection and its economic impact. Materials and Methods: Febrile hospitalized (n=219) patients with dengue fever diagnosed by a combination of MAC-ELISA, GAC-ELISA and NS1Antigen-ELISA were enrolled. Epidemiologic (including economic) parameters, clinical, radiological and laboratory manifestations were noted and patients followed up over the period of hospital stay...
June 2017: Iranian Journal of Microbiology
https://www.readbyqxmd.com/read/29207706/detection-of-blactx-m-extended-spectrum-beta-lactamase-producing-salmonella-enterica-serotype-typhi-in-a-tertiary-care-centre
#16
Aishwarya Ramachandran, Mariappan Shanthi, Uma Sekar
Introduction: Infections caused by Salmonella are an important public health threat in tropical and subtropical countries. Due to the emergence of resistance to ampicillin, chloramphenicol and trimethoprim/sulfamethoxazole (multidrug resistant salmonellae) in the late 1980s, fluoroquinolones and extended spectrum cephalosporins became the drugs of choice. Resistance to cefotaxime and ceftriaxone due to the production of Extended Spectrum Beta-Lactamase (ESBL) and reduced susceptibility to ciprofloxacin have emerged resulting in treatment failure...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29198381/during-the-emergency-department-evaluation-of-a-well-appearing-neonate-with-fever-should-empiric-acyclovir-be-initiated
#17
Eric Bruno, David Pillus, David Cheng, Gary Vilke, Nicholas Pokrajac
BACKGROUND: Herpes simplex virus (HSV) infection represents significant morbidity and mortality in the neonatal period. Although clear guidelines exist on the evaluation and management of the otherwise well-appearing febrile neonate pertaining to occult serious bacterial infections, there is no standardized approach regarding when to initiate testing and treatment for HSV infection. It is vital we establish a unified guideline based on available clinical research to aid in our decision to evaluate and initiate therapy for this disease...
November 29, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29196200/incidental-thrombotic-thrombocytopenic-purpura-during-acute-ischemic-stroke-and-thrombolytic-treatment
#18
İbrahim Acır, Hacı Ali Erdoğan, Vildan Yayla, Nilay Taşdemir, Murat Çabalar
BACKGROUND: Intravenous tissue plasminogen activator (IV tPA) was shown to be an effective treatment for acute ischemic stroke (AIS). According to stroke guidelines, there is no need to wait for the complete blood count (CBC) and coagulation test results before application of IV alteplase if there is no suspected coagulation disorder. In this study, a patient with AIS and thrombotic thrombocytopenic purpura (TTP) symptoms during thrombolytic treatment was presented. CASE: A 33-year-old male patient was admitted at the 2...
November 28, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29196066/cough-due-to-tb-and-other-chronic-infections-chest-guideline-and-expert-panel-report
#19
Stephen K Field, Patricio Escalante, Dina A Fisher, Belinda Ireland, Richard S Irwin
BACKGROUND: Cough is common in pulmonary TB and other chronic respiratory infections. Identifying features that predict whether pulmonary TB is the cause would help target appropriate individuals for rapid and cost-effective screening, potentially limiting disease progression and preventing transmission to others. METHODS: A systematic literature search for individual studies to answer eight key questions (KQs) was conducted according to established Chest Organization methods by using the following databases: MEDLINE via PubMed, Embase, Scopus, and the Cochrane Database of Systematic Reviews from January 1, 1984, to April 2014...
November 28, 2017: Chest
https://www.readbyqxmd.com/read/29188069/simultaneous-isolation-of-chryseobacterium-gleum-from-bloodstream-and-respiratory-tract-first-case-report-from-india
#20
Vidhi Jain, Nayani Amrin Fatema Afzal Hussain, Tasneem Siddiqui, Chinmoy Sahu, Malay Ghar, Kashi Nath Prasad
Introduction. Species of the genus Chryseobacterium are emerging healthcare-associated pathogens, often colonizing the hospital environment. There are no clear guidelines available for antimicrobial susceptibility of this organism. In this report we present the first case, to our knowledge, of simultaneous central-line-associated bloodstream infection (CLABSI) and ventilator-associated pneumonia (VAP) due to Chryseobacterium gleum from India. Case presentation. A 62 years old man with a history of a road traffic accident 1 month previously was referred to our center for further management...
October 2017: JMM Case Reports
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