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https://www.readbyqxmd.com/read/29786595/-genetically-determined-abnormal-electrical-activity-of-the-brain-and-the-heart
#1
Iwona Mańka-Gaca, Beata Łabuz-Roszak, Agnieszka Machowska-Majchrzak
Mutations leading to disorders within ion (mainly potassium and sodium) channels, have different degrees of expression in the brain and in the heart, which can cause simultaneous occurrence of disorders in both organs. This is manifested by the occurrence of epileptic seizures and cardiac electrical disturbances, further exacerbated by stimulation of autonomic structures within the central nervous system. In all patients with unclear paroxysmal disorders, and in those with unexplained sudden cardiac death, consideration should be given to the possibility of occurrence of genetically determined disorders in the ion channels...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29784241/fracture-probability-assessed-using-frax-%C3%A2-in-elderly-women-with-benign-paroxysmal-positional-vertigo
#2
Takafumi Nakada, Masaaki Teranishi, Yukio Ueda, Michihiko Sone
OBJECTIVE: Patients with benign paroxysmal positional vertigo (BPPV) can have vitamin D deficiency, which is a cause of abnormal bone turnover. Several studies have established a relationship between osteoporosis and BPPV. The World Health Organization Fracture Risk Assessment Tool, widely known as FRAX® (http://www.shef.ac.uk/FRAX), is a computer-based algorithm for assessing fracture risk. No direct comparison has been made between the FRAX scores of patients with BPPV and controls...
May 18, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29781518/an-interesting-case-of-wide-qrs-tachycardia-with-right-bundle-branch-block-morphology-what-is-the-mechanism
#3
Krishna Kumar Mohanan Nair, Narayanan Namboodiri, Hiren Kevadiya, Ajitkumar Valaparambil
A 30 year old gentleman with no structural heart disease has been evaluated for paroxysmal palpitation with documented regular wide QRS tachycardia that has not responded to IV adenosine. Surface electrocardiogram has not shown any pre-excitation. He has been taken for an EP study after informed consent. Diagnostic catheters were placed at coronary sinus (CS), His bundle region and right ventricle (RV). During catheter manipulation a regular wide QRS tachycardia with right bundle branch block morphology (RBBB) with a tachycardia cycle length (TCL) of 400 ms and normal QRS axis similar to the clinical tachycardia got induced (Fig:1)...
May 21, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29779325/-comparison-of-hemolytic-characteristics-among-paroxysmal-nocturnal-hemoglobinuria-autoimmune-hemolytic-anemia-and-hereditary-spherocytosis
#4
W W Li, J Shi, Z D Huang, N Nie, Y Q Shao, X X Li, M L Ge, J Zhang, J B Huang, P Jin, M Wang, Y Z Zheng
Objective: To determine the valuable hemolytic characteristics in differential diagnosis of paroxysmal nocturnal hemoglobinuria (PNH), autoimmune hemolytic anemia (AIHA) and hereditary spherocytosis (HS). Method: The clinical and hemolytic characteristics of 108 PNH patients, 127 AIHA patients and 172 HS patients diagnosed from January 1998 to April 2017 were compared. Results: ①Reticulocyte percentage (Ret%) of PNH patients [6.70% (0.14%-22.82%)] was significantly lower than that of AIHA [14.00%(0.10%-55...
April 14, 2018: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
https://www.readbyqxmd.com/read/29777080/paroxysmal-dyskinesia-in-the-bichon-frise
#5
Mark Lowrie, Artur S P Varejão
No abstract text is available yet for this article.
May 19, 2018: Veterinary Record
https://www.readbyqxmd.com/read/29776433/bordetella-pertussis-in-children-hospitalized-with-a-respiratory-infection-clinical-characteristics-and-pathogen-detection-in-household-contacts
#6
Juana Del Valle-Mendoza, Wilmer Silva-Caso, Miguel Angel Aguilar-Luis, Cristina Del Valle-Vargas, Erico Cieza-Mora, Johanna Martins-Luna, Ronald Aquino-Ortega, Andrea Silva-Vásquez, Jorge Bazán-Mayra, Pablo Weilg
OBJECTIVE: Describe the prevalence of Bordetella pertussis via PCR in children under 5 years old hospitalized as probable cases of pertussis and report the most common clinical features among them. RESULTS: A positive PCR result for B. pertussis was observed in 20.5% of our samples (18/88), one-third of them were from infants between 2 and 3 months old. The most common symptoms were paroxysms of coughing (88.9%), difficulty breathing (72.2%), cyanosis (77.8%) and fever (50%)...
May 18, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29775848/long-term-outcome-in-children-with-neonatal-seizures-a-tertiary-center-experience-in-cohort-of-168-patients
#7
Biljana Vucetic Tadic, Ruzica Kravljanac, Vlada Sretenovic, Vladislav Vukomanovic
PURPOSE: The purpose of this study was to evaluate long-term outcome and assess predictors of prognosis in children with neonatal seizures (NS). METHOD: This retrospective study includes children with NS treated at our Institute from January the 1st 2005 until December the 31st 2015. The data were collected from medical charts and the electroencephalogram (EEG) database at the Institute. The predictive value was evaluated for following parameters: (1) characteristics of the patients, such as gender, gestational age, birth body weight, Apgar score, artificial ventilation; (2) etiology; (3) characteristics of seizures such as type, time of onset, resistance to treatment; and (4) EEG background activity and paroxysmal discharges...
May 15, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29775029/-multi-canal-benign-paroxysmal-positional-vertigo-combined-anterior-canal
#8
H Q Yan, H Wang
No abstract text is available yet for this article.
February 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29775013/-effects-of-highly-selective-branches-neurotomy-of-vidian-nerve-with-low-temperature-plasma-on-vasoactive-intestinal-peptide-in-nasal-mucosal-cells-of-patients-with-allergic-rhinitis
#9
P He, X J Jin, H Zhao
Objective: The aim of this study is to investigate the effect of highly selective branches neurotomy of vidian nerve with low temperature plasma on the level of vasoactive intestinal peptide in nasal mucosa of patients with allergic rhinitis. Method: Fifty patients with allergic rhinitis were selected as the experimental group. At the same time, 50 normal adults in our hospital were selected as the control group. Highly selective branches neurotomy of vidian nerve with low temperature plasma was performed to observe the changes of vascular intestinal peptide levels in patients with nasal mucosa and the clinical efficacy...
February 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29771692/the-expanding-spectrum-of-paroxysmal-movement-disorders-update-from-clinical-features-to-therapeutics
#10
Eavan M McGovern, Emmanuel Roze, Timothy J Counihan
PURPOSE OF REVIEW: This review will discuss the expanding clinical spectrum of paroxysmal movement disorders and therapeutic options in light of emerging genotypic heterogeneity in these conditions. RECENT FINDINGS: Paroxysmal movement disorders comprise a heterogeneous group of rare neurological conditions characterized by intermittent episodes of abnormal movement associated with various triggers. As the clinical and genotypic spectrum of these disorders evolves, so also has the range of therapeutic options...
May 15, 2018: Current Opinion in Neurology
https://www.readbyqxmd.com/read/29771041/-analysis-of-118-cases-of-benign-paroxysmal-positional-vertigo-after-trauma
#11
H L Xue, C X Li, L X Duan, Y L Jing
Objective: The aim of this study is to retrospective analysis the clinic features of 118 cases of benign paroxysmal positional vertigo after trauma. Method: Analyzes clinic features of injury in 118 cases of benign paroxysmal positional vertigo after trauma, and classified and localized the craniocerebral trauma. The 118 cases were tested with different positioning tests in the sequence of Dix hallpike test and rolling test. Then, proper otolith manual reduction was given. Result: In 118 cases of BPPV after trauma including 35 cases of skull fracture, 6 cases of concussion, 17 cases of scalp hematoma, 28 cases of scalp laceration, 14 cases of mild brain contusion and 18 cases of head combined injury...
May 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29768630/what-determines-mortality-in-malignant-pheochromocytoma-report-of-a-case-with-eighteen-year-survival-and-review-of-the-literature
#12
Matheus de Oliveira Andrade, Vinícius Santos da Cunha, Dayana Carla de Oliveira, Olívia Laquis de Moraes, Adriana Lofrano-Porto
Pheochromocytoma (PCC) is a tumor derived from adrenomedullary chromaffin cells. Prognosis of malignant PCC is generally poor due to local recurrence or metastasis. We aim to report a case of malignant PCC with 18-year survival and discuss which factors may be related to mortality and long-term survival in malignant pheochromocytoma. The patient, a 45-year-old man, reported sustained arterial hypertension with paroxysmal episodes of tachycardia, associated with head and neck burning sensation, and hand and foot tremors...
March 2018: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29766449/value-of-an-old-school-approach-safety-and-long-term-success-of-radiofrequency-current-catheter-ablation-of-atrioventricular-nodal-reentrant-tachycardia-in-children-and-young-adolescents
#13
Henrike Siebels, Christian Sohns, Jan-Hendrik Nürnberg, Jürgen Siebels, Klaus Langes, Joachim Hebe
PURPOSE: Radiofrequency current energy (RFC) ablation is still considered as the gold standard for atrioventricular nodal reentrant tachycardia (AVNRT). Success-rates for AVNRT ablation vary irrespective of the ablation technology and strategy. This study aimed to access safety, efficacy, and long-term outcome of RFC catheter ablation for the treatment of AVNRT in children and adolescents aged < 19 years with special focus on modulation versus ablation of the AV nodal slow pathway (SP)...
May 15, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29764303/relief-from-intractable-phantom-pain-by-combining-psilocybin-and-mirror-visual-feedback-mvf
#14
Vilayanur Ramachandran, Chaipat Chunharas, Zeve Marcus, Timothy Furnish, Albert Lin
AL's leg was amputated resulting in phantom-limb pain (PLP). (1) When a volunteer placed her foot on or near the phantom - touching it evoked organized sensations in corresponding locations on AL's phantom. (2) Mirror-visual-feedback (MVF) relieved PLP, as did, "phantom massage". (3) Psilocybin-MVF pairing produced synergistic effects, complete elimination of PLP, and reduction in paroxysmal episodes. (4) Touching the volunteer's leg where AL previously had external fixators, evoked sensation of nails boring through the leg...
May 15, 2018: Neurocase
https://www.readbyqxmd.com/read/29761516/recurrence-rate-of-atrial-fibrillation-after-the-first-clinical-episode-a-prospective-evaluation-using-continuous-cardiac-rhythm-monitoring
#15
Emmanuel N Simantirakis, Panteleimon E Papakonstantinou, Emmanuel Kanoupakis, Gregory I Chlouverakis, Stylianos Tzeis, Panos E Vardas
BACKGROUND: Decision making regarding a patient who has experienced a first clinical episode of atrial fibrillation (AF) is challenging, and the AF recurrences should be a significant consideration. Continuous long-term rhythm monitoring via implantable loop recorders (ILRs) has enabled us to evaluate the AF recurrence profile after the first clinical episode and to investigate clinical parameters associated with the course of the arrhythmia. HYPOTHESIS: Continuous rhythm monitoring via ILRs in AF patients after the first clinical episode is of clinical significance and precisely evaluate the AF recurrence profile...
May 14, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29759785/manual-versus-robotic-catheter-ablation-for-the-treatment-of-atrial-fibrillation-the-man-and-machine-trial
#16
Andreas Rillig, Boris Schmidt, Luigi Di Biase, Tina Lin, Leonie Scholz, Christian H Heeger, Andreas Metzner, Daniel Steven, Peter Wohlmuth, Stephan Willems, Chintan Trivedi, Joseph G Galllinghouse, Andrea Natale, Feifan Ouyang, Karl-Heinz Kuck, Roland Richard Tilz
OBJECTIVES: Circumferential pulmonary vein isolation (CPVI) using irrigated radiofrequency is the most frequently used ablation technique for the treatment of atrial fibrillation worldwide. BACKGROUND: To date, no large randomized multicenter trials have evaluated the efficacy and safety of CPVI using robotic navigation (RN) systems compared with the current gold standard of manual ablation (MN). METHODS: In this prospective, international multicenter noninferiority trial, 258 patients with paroxysmal or persistent atrial fibrillation were randomized for CPVI using either RN (RN group, n = 131) or manual ablation (MN group, n = 127)...
August 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29759705/can-we-identify-the-extra-pulmonary-vein-substrate-in-paroxysmal-atrial-fibrillation-using-incremental-atrial-pacing
#17
EDITORIAL
Amir S Jadidi, Zoraida Moreno-Weidmann, Thomas Arentz
No abstract text is available yet for this article.
September 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29759622/5-year-outcome-of-pulmonary-vein-isolation-by-loss-of-pace-capture-on-the-ablation-line-versus-electrical-circumferential-pulmonary-vein-isolation
#18
Julia Moser, Arian Sultan, Jakob Lüker, Helge Servatius, Tim Salzbrunn, Manuel Altenburg, Benjamin Schäffer, Doreen Schreiber, Ruken Ö Akbulak, Julia Vogler, Boris A Hoffmann, Stephan Willems, Daniel Steven
OBJECTIVES: This study sought to compare long-term arrhythmia-free survival between electrical circumferential pulmonary vein isolation (PVI) and PVI with the endpoint of unexcitability along the ablation line. BACKGROUND: PVI is the standard ablation strategy of paroxysmal atrial fibrillation, although arrhythmia recurrence in long-term follow-up (FU) is high. The endpoint of unexcitability along the ablation line results in decreased arrhythmia recurrence compared to electrical PVI in 1-year FU...
November 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29759532/therapeutic-approaches-to-atrial-fibrillation-ablation-targeting-atrial-fibrosis
#19
REVIEW
Hans Kottkamp, Doreen Schreiber, Fabian Moser, Andreas Rieger
Atrial fibrosis is the fundamental histopathologic finding in atrial fibrillation (AF) patients and an important predictor of ablation failure beyond pulmonary vein isolation. There is wide variation in the extent and localization of left atrial fibrosis in patients with paroxysmal and nonparoxysmal AF. Box isolation of fibrotic areas is an effective rhythm control concept in patients with paroxysmal AF despite durable pulmonary vein isolation, and this strategy has recently been implemented successfully in initial AF ablation procedures in addition to pulmonary vein isolation for patients with nonparoxysmal AF...
July 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29759498/the-extent-of-mechanical-esophageal-deviation-to-avoid-esophageal-heating-during-catheter-ablation-of-atrial-fibrillation
#20
Chandrasekar Palaniswamy, Jacob S Koruth, Alexander J Mittnacht, Marc A Miller, Subbarao Choudry, Rahul Bhardwaj, Dinesh Sharma, Jonathan M Willner, Sujata S Balulad, Elizabeth Verghese, Georgios Syros, Anurag Singh, Srinivas R Dukkipati, Vivek Y Reddy
OBJECTIVES: This study sought to determine the extent of lateral esophageal displacement required during mechanical esophageal deviation (MED) and to eliminate luminal esophageal temperature elevation (LETElev ) during pulmonary vein (PV) isolation. BACKGROUND: MED is a conceptually attractive strategy of minimizing esophageal injury while allowing uninterrupted energy delivery along the posterior left atrium during PV isolation. METHODS: MED was performed using a malleable metal stylet within a plastic tube placed within the esophagus...
October 2017: JACC. Clinical Electrophysiology
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