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https://www.readbyqxmd.com/read/28812489/evaluating-outcomes-in-health-and-social-care-dickinson-helen-evaluating-outcomes-in-health-and-social-care-144pp-%C3%A2-12-99-janine-o-flynn-policy-press-9781447329763-1447329767-formula-see-text
#1
(no author information available yet)
One of a series of five books on interagency partnership in public health and social care, this book focuses on evaluation. It guides the reader through the outcomes evaluation process beginning with an explanation of what evaluation and outcomes are and why they matter.
August 16, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28812488/fast-facts-parkinson-s-disease-fourth-edition-chaudhuri-k-ray-fung-victor-sc-fast-facts-parkinson-s-disease-fourth-edition-168p-%C3%A2-15-health-press-9781908541932-1908541938-formula-see-text
#2
(no author information available yet)
Although small, this book is easy to read, well-structured and contains a vast amount of information on Parkinson's disease and its associated syndromes.
August 16, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28812050/caveats-in-the-established-understanding-of-cmt1a
#3
Jun Li
Charcot-Marie-Tooth disease type-1A (CMT1A) is one of the most common types of inherited peripheral nerve diseases. It is caused by the trisomy of chromosome 17p12 (c17p12), a large DNA segment of 1.4 Mb containing PMP22 plus eight other genes. The size of c17p12 is formidable for any cloning technique to manipulate, and thus precludes production of models in vitro and in vivo that can precisely recapitulate the genetic alterations in humans with CMT1A. This limitation and other factors have led to several assumptions, which have yet been carefully scrutinized, serving as key principles in our understanding of the disease...
August 2017: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/28811021/quantitative-analysis-of-major-and-trace-elements-in-nh4hf2-modified-silicate-rock-powders-by-laser-ablation-inductively-coupled-plasma-mass-spectrometry
#4
Wen Zhang, Zhaochu Hu, Yongsheng Liu, Wenwu Yang, Haihong Chen, Shenghong Hu, Hongyan Xiao
In this paper, we described a NH4HF2 digestion method as sample preparation for the rapid determination of major and trace elements in silicate rocks using laser ablation-inductively coupled plasma mass spectrometry (LA-ICP-MS). Sample powders digested by NH4HF2 at 230 °C for 3 h form ultrafine powders with a typical grain size d80 < 8.5 μm, and various silicate rocks have a consistent grain morphology and size, allowing us to produce pressed powder pellets that have excellent cohesion and homogeneity suitable for laser ablation micro-analysis without the addition of binder...
August 29, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28810913/selinexor-kpt-330-demonstrates-anti-tumor-efficacy-in-preclinical-models-of-triple-negative-breast-cancer
#5
Natalia Paez Arango, Erkan Yuca, Ming Zhao, Kurt W Evans, Stephen Scott, Charissa Kim, Ana Maria Gonzalez-Angulo, Filip Janku, Naoto T Ueno, Debu Tripathy, Argun Akcakanat, Aung Naing, Funda Meric-Bernstam
BACKGROUND: Selinexor (KPT-330) is an oral agent that has been shown to inhibit the nuclear exporter XPO1. Given the pressing need for novel therapies for triple-negative breast cancer (TNBC), we sought to determine the antitumor effects of selinexor in vitro and in vivo. METHODS: Twenty-six breast cancer cell lines of different breast cancer subtypes were treated with selinexor in vitro. Cell proliferation assays were used to measure the half-maximal inhibitory concentration (IC50) and to test the effects in combination with chemotherapy...
August 15, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28810817/struggles-over-antibiotics-physicians-stance-taking-toward-a-nonconforming-policy-in-an-intensive-care-unit
#6
Letizia Caronia, Marzia Saglietti
One of the most pressing contemporary health care challenges consists in rethinking antibiotic use to contrast the increase of multidrug resistant bacteria. Drawing on an ethnographic fieldwork in an Intensive Care Unit that adopts a nonconforming policy of antibiotic stewardship, this article analyzes doctor-doctor interaction concerning infectious disease diagnosis and antibiotic treatment. By analyzing examples of medical decision-making from a corpus of video-recorded morning briefings, we focus on physicians' stance-taking toward the ward's nonconforming policy and illustrate how it is contingently situated along a continuum from strong commitment to overt resistance...
August 1, 2017: Qualitative Health Research
https://www.readbyqxmd.com/read/28809700/cognitive-cost-of-using-augmented-reality-displays
#7
James Baumeister, Seung Youb Ssin, Neven A M ElSayed, Jillian Dorrian, David P Webb, James A Walsh, Timothy M Simon, Andrew Irlitti, Ross T Smith, Mark Kohler, Bruce H Thomas
This paper presents the results of two cognitive load studies comparing three augmented reality display technologies: spatial augmented reality, the optical see-through Microsoft HoloLens, and the video see-through Samsung Gear VR. In particular, the two experiments focused on isolating the cognitive load cost of receiving instructions for a button-pressing procedural task. The studies employed a self-assessment cognitive load methodology, as well as an additional dual-task cognitive load methodology. The results showed that spatial augmented reality led to increased performance and reduced cognitive load...
August 10, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28809699/ar-feels-softer-than-vr-haptic-perception-of-stiffness-in-augmented-versus-virtual-reality
#8
Yoren Gaffary, Benoit Le Gouis, Maud Marchal, Ferran Argelaguet, Bruno Arnaldi, Anatole Lecuyer
Does it feel the same when you touch an object in Augmented Reality (AR) or in Virtual Reality (VR)? In this paper we study and compare the haptic perception of stiffness of a virtual object in two situations: (1) a purely virtual environment versus (2) a real and augmented environment. We have designed an experimental setup based on a Microsoft HoloLens and a haptic force-feedback device, enabling to press a virtual piston, and compare its stiffness successively in either Augmented Reality (the virtual piston is surrounded by several real objects all located inside a cardboard box) or in Virtual Reality (the same virtual piston is displayed in a fully virtual scene composed of the same other objects)...
August 10, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28809466/tuning-phase-composition-of-polymer-nanocomposites-towards-high-energy-density-and-high-discharge-efficiency-by-non-equilibrium-processing
#9
Jianyong Jiang, Xin Zhang, Zhenkang Dan, Jing Ma, Yuanhua Lin, Ming Li, Ce-Wen Nan, Yang Shen
Polymer nanocomposite dielectrics with high energy density and low loss are major enablers for a number of applications in modern electronic and electrical industry. Conventional fabrication of nanocomposites by solution routes involves equilibrium process which is slow and results in structural imperfections, hence high leakage current and compromised reliability of the nanocomposites. We propose and demonstrate that a non-equilibrium process, which synergistically integrates electrospinning, hot-pressing and thermal quenching, is capable of yielding nanocomposites of very high quality...
August 15, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28809182/developing-an-assessment-tool-for-enhancing-interprofessional-education-of-patient-safety
#10
Yang Gong
The increasing recognition of the value of effective interprofessional collaboration has promoted interprofessional education (IPE) among healthcare professionals. The IPE pilot program initiative at UTHealth matriculated students from the disciplines of biomedical informatics, biomedical sciences, dentistry, medicine, nursing and public health. There has been a pressing need for developing an assessment tool in reflecting how IPE participants recognize and understand the other disciplines including clinical informatics in nowadays' practice...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28809162/statistical-signatures-of-a-targeted-search-by-bacteria
#11
Hossein Jashnsaz, Gregory G Anderson, Steve Pressé
Chemoattractant gradients are rarely well-controlled in nature and recent attention has turned to bacterial chemotaxis toward typical bacterial food sources such as food patches or even bacterial prey. In environments with localized food sources reminiscent of a bacterium's natural habitat, striking phenomena -- such as the volcano effect or banding -- have been predicted or expected to emerge from chemotactic models. However, in practice, from limited bacterial trajectory data it is difficult to distinguish targeted searches from an untargeted search strategy for food sources...
August 15, 2017: Physical Biology
https://www.readbyqxmd.com/read/28808982/radial-head-prosthesis-results-overview
#12
E Carità, A Donadelli, L Cugola, P Perazzini
BACKGROUND/PURPOSE: Radial head replacement is frequently used in treatment of radial head fractures or sequela. Impossibility to restore a correct anatomy, acute elbow traumatic instability and failure of osteosynthesis hardware are the most common indications. The authors describe their case studies and results on the implantation of various radial head prostheses. MATERIALS: Between June 2005 and June 2016, 28 radial head prostheses were implanted in the same number of patients with an average follow-up of 49 months (6-104)...
August 14, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/28808011/behavioral-responses-to-annual-temperature-variation-alter-the-dominant-energy-pathway-growth-and-condition-of-a-cold-water-predator
#13
Matthew M Guzzo, Paul J Blanchfield, Michael D Rennie
There is a pressing need to understand how ecosystems will respond to climate change. To date, no long-term empirical studies have confirmed that fish populations exhibit adaptive foraging behavior in response to temperature variation and the potential implications this has on fitness. Here, we use an unparalleled 11-y acoustic telemetry, stable isotope, and mark-recapture dataset to test if a population of lake trout (Salvelinus namaycush), a cold-water stenotherm, adjusted its use of habitat and energy sources in response to annual variations in lake temperatures during the open-water season and how these changes translated to the growth and condition of individual fish...
August 14, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28807618/repeatability-of-the-infant-food-reinforcement-paradigm-implications-of-individual-and-developmental-differences
#14
Kai Ling Kong, Rina D Eiden, Stephanie Anzman-Frasca, Corrin L Stier, Rocco A Paluch, Jessica Mendez, Emily Slominski, Gowthami Gengatharan, Leonard H Epstein
The relative reinforcing value of food versus engagement in other behaviors may be related to the development of obesity, and interventions to reduce FRR may decrease incidences of the development of future cases of obesity. Our laboratory recently developed a paradigm to measure the reinforcing value of food versus an alternative stimulus (i.e., playing with bubbles) in infants using a computerized laboratory task, during which infants press a button to earn reinforcers following a progressive ratio schedule of reinforcement...
August 11, 2017: Appetite
https://www.readbyqxmd.com/read/28807525/experimental-and-computational-analysis-of-micromotions-of-an-uncemented-femoral-knee-implant-using-elastic-and-plastic-bone-material-models
#15
Sanaz Berahmani, Dennis Janssen, Nico Verdonschot
It is essential to calculate micromotions at the bone-implant interface of an uncemented femoral total knee replacement (TKR) using a reliable computational model. In the current study, experimental measurements of micromotions were compared with predicted micromotions by Finite Element Analysis (FEA) using two bone material models: linear elastic and post-yield material behavior, while an actual range of interference fit was simulated. The primary aim was to investigate whether a plasticity model is essential in order to calculate realistic micromotions...
July 29, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28806689/fungal-diversity-of-tomme-d-orchies-cheese-during-the-ripening-process-as-revealed-by-a-metagenomic-study
#16
Alexandre Ceugniez, Bernard Taminiau, Françoise Coucheney, Philippe Jacques, Véronique Delcenserie, Georges Daube, Djamel Drider
Tomme d'Orchies is an artisanal pressed and uncooked cheese produced and marketed in the north of France. This study aimed at showing the fungal microbiota evolution of this cheese using a metagenetic based Illumina technology targeting the ITS2 domain of 5.8S fungal rDNAs. To this end, samples were taken from the rind and the core of different cheeses, after 0, 1, 3, 7, 14 and 21days of ripening. The data underpinned the prevalence of Yarrowia lipolytica and Galactomyces geotrichum for both microbiotas. Unusual species including Clavispora lusitaniae, Kazachstania unispora and Cladosporium cladosporioides were also detected, but their origins remain to be ascertained...
July 25, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28805730/effect-of-polymer-matrix-on-the-structure-and-electric-properties-of-piezoelectric-lead-zirconatetitanate-polymer-composites
#17
Rui Li, Jun Zhou, Hujun Liu, Jianzhong Pei
Piezoelectric lead zirconatetitanate (PZT)/polymer composites were prepared by two typical polymer matrixes using the hot-press method. The micromorphology, microstructure, dielectric properties, and piezoelectric properties of the PZT/polymer composites were characterized and investigated. The results showed that when the condition of frequency is 10³ Hz, the dielectric and piezoelectric properties of PZT/poly(vinylidene fluoride) were both better than that of PZT/polyvinyl chloride (PVC). When the volume fraction of PZT was 50%, PZT/PVDF prepared by the hot-press method had better comprehensive electric property...
August 14, 2017: Materials
https://www.readbyqxmd.com/read/28805502/the-fundamentals-of-cross-sector-collaboration-for-social-change-to-promote-population-health
#18
Joanne G de Montigny, Sylvie Desjardins, Louise Bouchard
Cross-sector collaboration is increasingly relied upon to tackle society's pressing and intractable problems. Chief among societal problems are unfavorable structural and social determinants of health. The ability to positively change these health determinants rests on the collaborative processes and structures of governance across diverse sectors in society. The purpose of this article is to present a conceptual framework that sheds light on the basic requirements of cross-sector collaboration for social change to promote the health of populations...
August 1, 2017: Global Health Promotion
https://www.readbyqxmd.com/read/28805429/the-effect-of-scopolamine-on-matching-behavior-and-the-estimation-of-relative-reward-magnitude
#19
Matthew I Leon, Vanessa Rodriguez-Barrera, Aldo Amaya
We investigated the behavioral effects of scopolamine on rats that bar pressed for trains of electrically stimulating pulses under concurrent variable interval schedules of reward. For the first half of the session (30 min) a 1:4 ratio in the programmed number of stimulation trains delivered at each option was in effect. At the start of the second half of the session, an unsignaled reversal in the relative train number (4:1) occurred. We tracked the relative magnitude of reward estimated for each contiguous pair of reinforced visits to competing options...
August 14, 2017: Behavioral Neuroscience
https://www.readbyqxmd.com/read/28805071/a-systematic-review-of-quality-of-life-of-adults-on-the-autism-spectrum
#20
Michael Ayres, Jeremy R Parr, Jacqui Rodgers, David Mason, Leah Avery, Darren Flynn
Autism spectrum disorder is associated with co-existing conditions that may adversely affect an individual's quality of life. No systematic review of quality of life of adults on the autism spectrum has been conducted. Our objectives were as follows: (1) review the evidence about quality of life for adults on the autism spectrum; (2) critically appraise current practice in assessing quality of life of adults on the autism spectrum. We searched bibliographic databases and other literature to identify studies using a direct measure of quality of life of adults on the autism spectrum...
August 1, 2017: Autism: the International Journal of Research and Practice
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