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https://www.readbyqxmd.com/read/28645064/heroin-and-saccharin-demand-and-preference-in-rats
#1
Lindsay P Schwartz, Jung S Kim, Alan Silberberg, David N Kearns
BACKGROUND: Several recent studies have investigated the choice between heroin and a non-drug alternative reinforcer in rats. A common finding in these studies is that there are large individual differences in preference, with some rats preferring heroin and some preferring the non-drug alternative. The primary goal of the present study was to determine whether individual differences in how heroin or saccharin is valued, based on demand analysis, predicts choice. METHODS: Rats lever-pressed for heroin infusions and saccharin reinforcers on fixed-ratio schedules...
June 13, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28644678/professional-athletes-return-to-play-and-performance-after-operative-repair-of-an-achilles-tendon-rupture
#2
David P Trofa, J Chance Miller, Eugene S Jang, Denzel R Woode, Justin K Greisberg, J Turner Vosseller
BACKGROUND: Most Achilles tendon ruptures are sports related. However, few studies have examined and compared the effect of surgical repair for complete ruptures on return to play (RTP), play time, and performance across multiple sports. PURPOSE: To examine RTP and performance among professional athletes after Achilles tendon repair and compare pre- versus postoperative functional outcomes of professional athletes from different major leagues in the United States...
June 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28643230/crosstalk-between-m2-macrophages-and-glioma-stem-cells
#3
Leora M Nusblat, Molly J Carroll, Charles M Roth
PURPOSE: Given its extremely poor prognosis, there is a pressing need for an improved understanding of the biology of glioblastoma multiforme (GBM), including the roles of tumor subpopulations that may contribute to their growth rate and therapy resistance. The most malignant phenotypes of GBM have been ascribed to the presence of subpopulations of cancer stem cells (CSCs), which are resistant to chemotherapeutic drugs and ionizing radiation and which promote invasiveness and metastasis...
June 22, 2017: Cellular Oncology (Dordrecht)
https://www.readbyqxmd.com/read/28642002/development-of-geriatric-mental-health-learning-objectives-for-medical-students-a-response-to-the-institute-of-medicine-2012-report
#4
Susan W Lehmann, William B Brooks, Dennis Popeo, Kirsten M Wilkins, Mary C Blazek
America is aging as the population of older adults increases. The shortage of geriatric mental health specialists means that most geriatric mental healthcare will be provided by physicians who do not have specialty training in geriatrics. The Institute of Medicine Report of 2012 highlighted the urgent need for development of national competencies and curricula in geriatric mental health for all clinicians. Virtually all physicians can expect to treat older patients with mental health symptoms, yet currently there are no widely accepted learning objectives in geriatric mental health specific for medical students...
May 12, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28641798/hiv-1-associated-atherosclerosis-unraveling-the-missing-link
#5
REVIEW
Alison Kearns, Jennifer Gordon, Tricia H Burdo, Xuebin Qin
Cardiovascular disease, including atherosclerosis and atherosclerosis-associated complications, is an increasing cause of morbidity and mortality in human immunodeficiency virus (HIV) patients in the post-antiretroviral therapy era. HIV alone accelerates atherosclerosis. Antiretroviral therapy; HIV-associated comorbidities, such as dyslipidemia, drug abuse, and opportunistic infections; and lifestyle are risk factors for HIV-associated atherosclerosis. However, our current understanding of HIV-associated atherogenesis is very limited and has largely been obtained from clinical observation...
June 27, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28640889/contrasting-academic-and-lay-press-print-coverage-of-the-2013-2016-ebola-virus-disease-outbreak
#6
Mark D Kieh, Elim M Cho, Ian A Myles
Under a traditional paradigm, only those with the expected background knowledge consume academic literature. The lay press, as well as government and non-government agencies, play a complementary role of extracting findings of high interest or importance and translating them for general viewing. The need for accurate reporting and public advising is paramount when attempting to tackle epidemic outbreaks through behavior change. Yet, public trust in media outlets is at a historic low. The Crisis and Emergency Risk Communication (CERC) model for media reporting on public health emergencies was established in 2005 and has subsequently been used to analyze media reporting on outbreaks of influenza and measles as well as smoking habits and medication compliance...
2017: PloS One
https://www.readbyqxmd.com/read/28640772/the-effect-of-a-carbohydrate-mouth-rinse-on-upper-body-muscular-strength-and-endurance
#7
James E Dunkin, Shaun M Phillips
Dunkin, JE and Phillips, SM. The effect of a carbohydrate mouth rinse on upper-body muscular strength and endurance. J Strength Cond Res 31(7): 1948-1953, 2017-Carbohydrate (CHO) mouth rinsing rapidly increases corticomotor output and maximal muscle force production, which could enhance muscular strength and endurance during resistance exercise. However, previous research has found no effect of CHO rinsing on muscular strength or endurance. The current study altered the CHO rinse composition and frequency and the muscular endurance test to further investigate the effects of a CHO mouth rinse on upper-body muscular strength and endurance...
July 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28639839/biocompatible-agarose-chitosan-coated-silver-nanoparticle-composite-for-soft-tissue-engineering-applications
#8
Nupur Kumar, Dayananda Desagani, Girish Chandran, Narendra Nath Ghosh, Ganesh Karthikeyan, Sachin Waigaonkar, Anasuya Ganguly
With increasing gap in the demand and supply of vital organs for transplantation there is a pressing need to bridge the gap with substitutes. One way to make substitutes is by tissue engineering which involves combining several types of synthetic or biomaterials, cells and growth factors cross-linked together to synthesize a functional scaffold for repair or replacement of non-functional organs. Nanoparticle based composites are gaining importance in tissue engineering due to their ability to enhance cell attachment and proliferation...
June 22, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28639823/our-own-action-kinematics-predict-the-perceived-affective-states-of-others
#9
Rosanna Edey, Daniel Yon, Jennifer Cook, Iroise Dumontheil, Clare Press
Our movement kinematics provide useful cues about our affective states. Given that our experiences furnish models that help us to interpret our environment, and that a rich source of action experience comes from our own movements, in the present study, we examined whether we use models of our own action kinematics to make judgments about the affective states of others. For example, relative to one's typical kinematics, anger is associated with fast movements. Therefore, the extent to which we perceive anger in others may be determined by the degree to which their movements are faster than our own typical movements...
July 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/28639205/roger-j-r-levesque-adolescents-privacy-and-the-law-a-developmental-science-perspective-new-york-ny-oxford-university-press-2016-232-pp-isbn-9780190460792
#10
https://www.readbyqxmd.com/read/28638880/efficiency-of-borage-seeds-oil-against-gamma-irradiation-induced-hepatotoxicity-in-male-rats-possible-antioxidant-activity
#11
Hala A H Khattab, Inas Z A Abdallah, Fatimah M Yousef, Etimad A Huwait
BACKGROUND: Borage (Borago officinal L.) is an annual herbaceous plant of great interest because its oil contains a high percentage of γ-linolenic acid (GLA). The present work was carried out to detect fatty acids composition of the oil extracted from borage seeds (BO) and its potential effectiveness against γ-irradiation- induced hepatotoxicity in male rats. MATERIALS AND METHODS: GC-MS analysis of fatty acids methyl esters of BO was performed to identify fatty acids composition...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28638200/brain-gamma-aminobutyric-acid-gaba-concentration-of-the-prefrontal-lobe-in-unmedicated-patients-with-obsessive-compulsive-disorder-a-research-of-magnetic-resonance-spectroscopy
#12
Zongfeng Zhang, Qing Fan, Yanle Bai, Zhen Wang, Haiyin Zhang, Zeping Xiao
BACKGROUND: In recent years, a large number of neuroimaging studies found that the Cortico-Striato- Thalamo-Cortical circuit (CSTC), including the prefrontal lobe, a significant part of CSTC, has disturbance metabolically in patients with Obsessive-Compulsive Disorder (OCD). AIM: Explore the correlation between the neuro-metabolic features and clinical characteristics of OCD patients using magnetic resonance spectroscopy technology. METHODS: 88 patients with OCD who were not received medication and outpatient treatment for 8 weeks and 76 health controls were enrolled, there was no significant difference in gender, age or education level between the two groups...
October 25, 2016: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28637471/enhanced-humoural-and-cellular-immune-responses-to-influenza-h7n9-antigen-ha1-2-fused-with-flagellin-in-chickens
#13
Li Song, Dan Xiong, Maozhi Hu, Xilong Kang, Zhiming Pan, Xinan Jiao
BACKGROUND: Sudden increases in the number of human A (H7N9) cases reported during December and January have been observed in previous years. Most reported infection cases are due to prior exposure to live poultry or potentially contaminated environments. Low pathogenicity of influenza A (H7N9) virus in avian species complicates timely discovery of infected birds. Therefore, there is a pressing need to develop safe and effective anti-H7N9 vaccines for poultry to reduce the risk of human infection and prevent the emergence of novel mutated strains...
June 21, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28637395/book-review-bioethics-a-philosophical-introduction-holland-s-2017-bioethics-a-philosophical-introduction-cambridge-uk-polity-press-273-pp-27-36-paper-isbn-978-0-7456-9059-5
#14
Heidi Matisonn
No abstract text is available yet for this article.
July 2017: Journal of Empirical Research on Human Research Ethics: JERHRE
https://www.readbyqxmd.com/read/28637360/who-or-what-has-agency-in-the-discussion-of-antimicrobial-resistance-in-uk-news-media-2010-2015-a-transitivity-analysis
#15
Luke Curtis Collins, Rusi Jaspal, Brigitte Nerlich
The increase in infections resistant to the existing antimicrobial medicines has become a topic of concern for health professionals, policy makers and publics across the globe; however, among the public there is a sense that this is an issue beyond their control. Research has shown that the news media can have a significant role to play in the public's understanding of science and medicine. In this article, we respond to a call by research councils in the United Kingdom to study antibiotic or antimicrobial resistance as a social phenomenon by providing a linguistic analysis of reporting on this issue in the UK press...
June 1, 2017: Health (London)
https://www.readbyqxmd.com/read/28637286/structure-seq2-sensitive-and-accurate-genome-wide-profiling-of-rna-structure-in-vivo
#16
Laura E Ritchey, Zhao Su, Yin Tang, David C Tack, Sarah M Assmann, Philip C Bevilacqua
RNA serves many functions in biology such as splicing, temperature sensing, and innate immunity. These functions are often determined by the structure of RNA. There is thus a pressing need to understand RNA structure and how it changes during diverse biological processes both in vivo and genome-wide. Here, we present Structure-seq2, which provides nucleotide-resolution RNA structural information in vivo and genome-wide. This optimized version of our original Structure-seq method increases sensitivity by at least 4-fold and improves data quality by minimizing formation of a deleterious by-product, reducing ligation bias, and improving read coverage...
June 16, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28635320/book-review-a-concise-introduction-to-mental-health-in-canada-a-concise-introduction-to-mental-health-in-canada-second-edition-goldner-elliott-m-jenkins-emily-bilsker-dan-toronto-ontario-canadian-scholars-press-2016-371-pages-book-3731-cdn-79-95-reviewer-rating
#17
https://www.readbyqxmd.com/read/28634886/subcortical-brain-atrophy-in-gulf-war-illness
#18
Peka Christova, Lisa M James, Brian E Engdahl, Scott M Lewis, Adam F Carpenter, Apostolos P Georgopoulos
Gulf War Illness (GWI) is a multisystem disorder that has affected a substantial number of veterans who served in the 1990-1991 Gulf War. The brain is prominently affected, as manifested by the presence of neurological, cognitive and mood symptoms. Although brain dysfunction in GWI has been well documented (EBioMedicine 12:127-32, 2016), abnormalities in brain structure have been debated. Here we report a substantial (~10%) subcortical brain atrophy in GWI comprising mainly the brainstem, cerebellum and thalamus, and, to a lesser extent, basal ganglia, amygdala and diencephalon...
June 20, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28634390/increased-glutamate-in-somatosensory-cortex-in-functional-dyspepsia
#19
Arthur D P Mak, Georg Northoff, David K W Yeung, Winnie C W Chu, Steve C N Hui, Cynthia Cheung, Jessica Ching, Linda Lam, Sing Lee, Justin Wu
Functional Dyspepsia-Post-prandial Distress Syndrome (FD-PDS) was associated with mood-related increases in resting activity and lowered activation threshold in the somatosensory cortex (SSC), insula and perigenual anterior cingulate cortex(pgACC) in functional imaging studies. The underlying cortical neurochemical changes are unknown. We performed proton Magnetic Resonance Spectroscopy (1H-MRS) on 17 consecutive tertiary clinic-recruited psychotropic-naïve Rome III FD-PDS female and 17 age-sex matched healthy controls...
June 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28634107/chronic-pramipexole-treatment-induces-compulsive-behavior-in-rats-with-6-ohda-lesions-of-the-substantia-nigra-and-ventral-tegmental-area
#20
D Dardou, L Reyrolle, C Chassain, F Durif
Dopamine replacement therapy (DRT) reduces motor symptoms in Parkinson's disease (PD), but also induces impulsive-compulsive behavior (ICB) in up to 25% of PD patients. These non-motor side effects of DRT generally follow a gradual transition from impulsive to compulsive-like-i.e. repetitive, compelled, and non-pleasurable-behavior. Here, we investigated the effect of chronic pramipexole (PPX) treatment on the onset of compulsive-like behavior, measured via the post-training signal attenuation (PTSA) procedure, in rats with dopaminergic lesions...
June 17, 2017: Behavioural Brain Research
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