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Splenic segmentation

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https://www.readbyqxmd.com/read/29888657/oral-administration-of-bifidobacterium-bifidum-tmc3115-to-neonatal-mice-may-alleviate-ige-mediated-allergic-risk-in-adulthood
#1
R Y Cheng, J R Yao, Q Wan, J W Guo, F F Pu, L Shi, W Hu, Y H Yang, L Li, M Li, F He
This study aimed to demonstrate whether exposure to bifidobacteria during early life influences immunity and alleviates the risk of immunoglobulin E (IgE)-mediated allergies in adulthood. BALB/c neonatal mice (n=54) were administered with a lyophilised cell preparation of Bifidobacterium bifidum TMC3115 (TMC3115) for 3 weeks. Following the intervention, the mice were immunised with intraperitoneal ovalbumin (OVA). The morphology and function of the intestinal epithelium were determined using histopathological examinations...
June 11, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/29781346/distribution-characteristics-of-cells-in-splenomegaly-due-to-hepatitis-b-related-cirrhotic-portal-hypertension-and-their-clinical-importance
#2
Xiaoyu Han, Yunfu Lv, Yejuan Li, Jie Deng, Qingan Qiu, Ning Liu, Shuya Zhao, Caixian Liao
Objectives To investigate peripheral cytopenia in patients with splenomegaly due to hepatitis B-related cirrhotic portal hypertension (HBRCPH) by comparing blood cell counts from enlarged spleens with peripheral blood. Methods This prospective study involved patients undergoing splenectomy at the Nangfang Hospital from June 2013 to December 2015. Blood cell counts from peripheral blood were compared with those from splenic blood taken during splenectomies. Results Clinical data were available from 30 patients...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29741690/severe-multisystem-involvement-of-chronic-granulomatous-disease-in-a-pediatric-patient
#3
Zuhal Bayramoglu, Ibrahim Adaletli, Emine Caliskan, Manolya Acar, Selda Hancerli Torun, Ayper Somer
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder identified by recurrent pyogenic and fungal infections infections secondary to defective nicotinamide adenine dinucleotide phosphate oxidase enzyme. In the present study, we demonstrated a case with a history of multiple segmental lung resections because of invasive bronchopulmonary aspergillosis, multifocal hepatic and splenic granulomas, bilateral adnexal calcific foci presumed to be related with old granulomatous infection and finally gastric outlet obstruction secondary to the involvement of the stomach wall thickening with granulomatous tissue...
May 7, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29679240/a-case-of-tension-faecopneumothorax-after-delayed-diagnosis-of-traumatic-diaphragmatic-hernia
#4
Tien Yew Chern, Allan Kwok, Soni Putnis
BACKGROUND: Traumatic diaphragmatic injuries from blunt or penetrating trauma are difficult to detect in the acute setting and, if missed, can result in significant morbidity and mortality in the future. We present a case demonstrating the natural progression of this resulting in faecopneumothorax, which is a rare but serious presentation. CASE PRESENTATION: A 22-year-old young man presented with left upper quadrant and chest pain, nausea, vomiting, and intermittent obstipation with a background of previous lower chest wall stabbings...
April 20, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/29619907/severe-atherosclerosis-in-donor-liver-vasculature-an-illustrative-case-report-and-review-of-the-literatur
#5
Ayokunle S Olowofela, Oscar K Serrano, Raja Kandaswamy
As the scarcity of transplantable organs continues to increase, juxtaposed with an aging donor population, transplant surgeons are increasingly confronted with marginal organ offers. The presence of atherosclerosis in the donor allograft has been shown to compromise the vascular integrity and predispose to vascular complications in the transplanted liver. Here, we present a case of 54-year-old brain-dead donor who was discovered to have a severely diseased aorta during organ recovery. Pathologic evaluation revealed severe atherosclerosis with calcifications...
April 4, 2018: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/29555782/oncolytic-reovirus-inhibits-immunosuppressive-activity-of-myeloid-derived-suppressor-cells-in-a-tlr3-dependent-manner
#6
Yuki Katayama, Masashi Tachibana, Nozomi Kurisu, Yukako Oya, Yuichi Terasawa, Hiroshi Goda, Kouji Kobiyama, Ken J Ishii, Shizuo Akira, Hiroyuki Mizuguchi, Fuminori Sakurai
Oncolytic reovirus, which possesses 10 segments of dsRNA genome, mediates antitumor effects via not only virus replication in a tumor cell-specific manner, but also activation of antitumor immunity; however, the mechanism(s) of reovirus-induced activation of antitumor immunity have not been fully elucidated. Recent studies have demonstrated that overcoming an immunosuppressive environment in tumor-bearing hosts is important to achieve efficient activation of antitumor immunity. Among the various types of cells involved in immunosuppression, it has been revealed that myeloid-derived suppressor cells (MDSCs) are significantly increased in tumor-bearing hosts and play crucial roles in the immunosuppression in tumor-bearing hosts...
April 15, 2018: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/29535095/case-of-segmental-arterial-mediolysis
#7
Maneka M Britto, Matthew Lukies, Charles Milne, Timothy Joseph, James C Lee
Segmental arterial mediolysis (SAM) is a rare, non-inflammatory, vascular condition that predominantly affects medium-sized to large-sized abdominal arteries and can present with haemorrhage into the abdominal cavity. We report the case of a patient with SAM of the coeliac, splenic, renal and gastroduodenal arteries in whom endovascular coil embolisation was successfully used to treat a bleeding gastroduodenal artery pseudoaneurysm.
March 13, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29521825/lymphatic-drainage-of-the-splenic-flexure-defined-by-intraoperative-scintigraphic-mapping
#8
Carolyn E Vasey, Siraj Rajaratnam, Gregory O'Grady, Mike Hulme-Moir
BACKGROUND: The optimal surgical management of splenic flexure cancer is debated, partly because of an incomplete understanding of the lymphatic drainage of this region. OBJECTIVE: This study aimed to evaluate the normal lymphatic drainage of the human splenic flexure using laparoscopic scintigraphic mapping. DESIGN: This was a clinical trial. SETTINGS: The study was conducted at a single tertiary care center. PATIENTS: Thirty consecutive patients undergoing elective colorectal resections without splenic flexure pathology were recruited...
April 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29462751/primary-splenic-malignant-lymphoma-mimicking-metastasis-of-rectosigmoid-cancer-a-case-report
#9
Masaki Wakasugi, Yumiko Yasuhara, Yujiro Nakahara, Takashi Matsumoto, Hiroyoshi Takemoto, Ko Takachi, Kiyonori Nishioka, Kyotaro Yoshida, Satoshi Oshima
INTRODUCTION: Primary splenic malignant lymphoma is quite a rare disease, and its preoperative diagnosis is difficult. CASE PRESENTATION: An 80-year-old man was diagnosed with advanced rectosigmoid cancer with liver and splenic metastases, for which he underwent single-incision laparoscopic high anterior resection for the primary rectosigmoid cancer. After chemotherapy, he underwent laparoscopy-assisted splenectomy and open partial hepatectomy of segment 3 and segment 5/6 of the liver...
2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29446669/segmental-arterial-mediolysis-abdominal-imaging-of-and-disease-course-in-111-patients
#10
Sailen G Naidu, Christine O Menias, Rahmi Oklu, Robert S Hines, Kinan Alhalabi, Gerges Makar, Fadi E Shamoun, Stanislav Henkin, Robert D McBane
OBJECTIVE: The purpose of this study is to identify the imaging characteristics of segmental arterial mediolysis (SAM) at presentation and establish the longitudinal course of disease. MATERIALS AND METHODS: We retrospectively identified patients with SAM at a single institution from 2000 through 2015. Diagnosis was based on published guidelines with multidisciplinary consensus. Imaging studies obtained at initial evaluation were reviewed to evaluate imaging findings and vascular territory distribution...
April 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29423167/a-rare-case-of-massive-lower-gastrointestinal-bleeding-from-a-ruptured-splenic-artery-aneurysm
#11
Ravi Maharaj, Barry Raghunanan, Wayne Mohammed, Rakesh Rambally, Vandana Devika Sookdeo, Dave Harnanan, Wayne A Warner
Splenic artery aneurysms (SAAs) are an extremely rare cause of asymptomatic massive lower gastrointestinal bleeding with less than a handful of patients surviving such a presentation. A 24-year-old female presented in shock after multiple episodes of massive rectal bleeding. Imaging revealed a heterogeneous mass arising from the tail of the pancreas eroding into the splenic flexure of the colon. Further episodes of bleeding led to an exploratory laparotomy. Intraoperatively, a suspected neoplastic process arising from the tail of the pancreas with contiguous involvement of the splenic flexure of the colon and the greater curvature of the stomach was noted...
February 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29377873/arc-of-riolan-preserving-splenic-flexure-takedown-during-anterior-resection-potentially-critical-to-prevent-acute-anastomotic-ischemia
#12
James Wei Tatt Toh, Ronnie Matthews, Seon-Hahn Kim
INTRODUCTION: The Arc of Riolan is a strategic vessel that provides collateral mesenteric circulation in 10% of individuals. The importance of identifying and preserving the arc of Riolan in reducing the risk of ischemia to the proximal anastomotic segment after high ligation anterior resection was evaluated. TECHNIQUE: The arc of Riolan is a vessel that crosses anterior to the inferior mesenteric vein horizontally below the level of the pancreas. A retrospective review of all recorded videos of laparoscopic and robotic low and ultra-low anterior resections was performed in September to December 2012 and prospective evaluation in April to July 2013...
March 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29361367/management-of-the-colorectal-polyp-referred-for-resection-a-case-matched-comparison-of-advanced-endoscopic-surgery-and-laparoscopic-colectomy
#13
Maysoon Gamaleldin, Cigdem Benlice, Conor P Delaney, Scott Steele, Emre Gorgun
BACKGROUND: Colonoscopy is the gold standard for colorectal screening and surveillance. Advanced endoscopic polypectomy techniques such as endoscopic submucosal dissection (ESD) have been introduced to remove large colorectal polyps. Our aim was to compare the outcomes of patients who underwent ESD with those of who underwent laparoscopic colectomy for benign colorectal polyps. METHODS: Patients with a preoperative diagnosis of benign colorectal polyp who underwent ESD or colectomy between 2011 and 2016 were case matched for age, sex, body mass index, American Society of Anesthesiologists status, polyp size, and location...
March 2018: Surgery
https://www.readbyqxmd.com/read/29320559/characterization-of-the-naive-murine-antibody-repertoire-using-unamplified-high-throughput-sequencing
#14
Trisha A Rettig, Claire Ward, Bailey A Bye, Michael J Pecaut, Stephen K Chapes
Antibody specificity and diversity are generated through the enzymatic splicing of genomic gene segments within each B cell. Antibodies are heterodimers of heavy- and light-chains encoded on separate loci. We studied the antibody repertoire from pooled, splenic tissue of unimmunized, adult female C57BL/6J mice, using high-throughput sequencing (HTS) without amplification of antibody transcripts. We recovered over 90,000 heavy-chain and over 135,000 light-chain immunoglobulin sequences. Individual V-, D-, and J-gene segment usage was uniform among the three mouse pools, particularly in highly abundant gene segments, with low frequency V-gene segments not being detected in all pools...
2018: PloS One
https://www.readbyqxmd.com/read/29313164/treatment-of-nonocclusive-mesenteric-ischemia-with-type-b-aortic-dissection-using-intra-arterial-catheterization-after-trauma-surgery-case-report
#15
Sho Fujiwara, Yuki Sekine, Ryuichi Nishimura, Kazuya Tadasa, Shukichi Miyazaki
BACKGROUND: Nonocclusive mesenteric ischemia (NOMI) is a mesenteric arterial spasm and intestinal ischemia. This disease is a highly lethal disease because diagnosis and decision of appropriate treatments are often difficult. Operations cannot resolve the spasms and may worsen the situation. However, the safety and effectiveness of catheterization for NOMI with aortic dissection (AD) have not yet been elucidated. Here, we report a successful case of early diagnosis and treatment of NOMI with type B AD involving the superior mesenteric artery (SMA) using the intra-arterial infusion of a vasodilator via the SMA...
January 8, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/29197396/new-laparoscopic-procedure-for-left-sided-pancreatic-cancer-artery-first-approach-laparoscopic-ramps-using-3d-technique
#16
Michihiro Yamamoto, Masazumi Zaima, Hidekazu Yamamoto, Hideki Harada, Junichiro Kawamura, Masahiro Yamada, Tekefumi Yazawa, Junya Kawasoe
BACKGROUND: For left-sided pancreatic ductal adenocarcinoma (PDAC), radical antegrade modular pancreatosplenectomy (RAMPS) is a reasonable surgical approach for tumor-free margin resection and systemic lymph node clearance. In pancreaticoduodenectomy for PDAC, the superior mesenteric artery (SMA)-first approach (or the "artery-first approach") has become the standard procedure. With improvements in laparoscopic instruments and techniques, some surgeons attempted to apply laparoscopic RAMPS (L-RAMPS) for carefully selected patients with left-sided PDAC...
December 2, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29190873/-segmental-portal-hypertension-with-splenic-vein-thrombosis-caused-by-pancreatitis
#17
Luis Franco-Avilés, Federico I Hernández-Rocha, Ulises Mercado, Cristian G Malvido-Torres
BACKGROUND: Splenic vein thrombosis is a complication of pancreatic carcinoma, pancreatitis or pancreatic pseudocyst. It may lead to segmental portal hypertension and bleeding from gastric varices. CLINICAL CASE: A 31 year-old man was diagnosed with pancreatitis of two weeks of evolution and was referred to our hospital in 2013. He had a history of alcohol consumption. Physical examination showed no stigmata of liver cirrhosis. Laboratory analyses revealed hemoglobin 9...
November 2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29078654/unusual-case-of-subxiphoid-uniportal-vats-right-upper-lobectomy-in-a-patient-with-interrupted-inferior-vena-cava-with-azygous-continuation
#18
Firas Emad Abu Akar, Chenlu Yang, Yiming Zhou, Lei Lin, Diego Gonzalez-Rivas, Lei Jiang
Interrupted IVC (also known as Azygos continuation of the inferior vena cava) is a relatively uncommon congenital condition with prevalence 1.5% (0.2-3%) of the general population (Bass et al .). Although it's usually asymptomatic condition, splenic or cardiac abnormalities could be associated (Hardwick et al .). Incidental diagnosis during prenatal ultrasound screening or by routine imaging is the most common scenario. Special attention is required during right side thoracic procedures surgical resections in order to avoid scarifying the azygos vein that could lead to fatal results (Effler et al ...
2017: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/28971378/endoscopic-ultrasound-guided-transmural-drainage-of-walled-off-pancreatic-necrosis-in-patients-with-portal-hypertension-and-intra-abdominal-collaterals
#19
Surinder S Rana, Ravi Sharma, Sobur Uddin Ahmed, Rajesh Gupta
BACKGROUND: Acute necrotizing pancreatitis (ANP) is complicated with segmental portal hypertension (PHT) and formation of venous collaterals. Presence of collaterals in vicinity of endoscopic transmural tract can lead to potentially catastrophic situation. Here, we report safety and outcome of EUS-guided transmural drainage of walled-off pancreatic necrosis (WOPN) in patients with PHT and intra-abdominal collaterals. METHODS: Retrospective analysis of collected database of patients (n=18; age 40...
September 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28740966/portal-vein-thrombosis-as-a-rare-cause-of-abdominal-pain-when-to-consider
#20
Cengiz Tavusbay, Erdinç Kamer, Turan Acar, İbrahim Kokulu, Haldun Kar, Özlem Gür
Extrahepatic portal vein thrombosis (PVT) is a rare condition that is characterized by the presence of thrombus within any segment of the portal vein, including the right and left intrahepatic branches. It may also extend to the splenic or superior mesenteric veins. Portal vein thrombosis may be related to cirrhosis or liver malignancy as well as to local inflammatory conditions in the abdomen and genetic or acquired thrombophilic diseases. Currently, PVT is being increasingly diagnosed due to advances in modern imaging techniques...
2017: Turkish Journal of Surgery
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