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Splenic lymph nodes

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https://www.readbyqxmd.com/read/28733739/variation-and-treatment-of-vessels-in-laparoscopic-right-hemicolectomy
#1
Kai Ye, Jianan Lin, Yafeng Sun, Yiyang Wu, Jianhua Xu, Songbing He
BACKGROUND: With the introduction of complete mesocolic excision (CME) and the application of laparoscopic technique, surgery for colon cancer has become more standardized and the curative effect has improved [1]. The key points in laparoscopic right hemicolectomy are high ligation of main vessels and root dissection of lymph nodes. The wide range of variations in vascular architecture and intraoperative bleeding are common causes of prolonged surgical time, wound hemorrhage, and even transfer to the opening operation...
July 21, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28709626/subtotal-colectomy-versus-left-hemicolectomy-for-the-elective-treatment-of-splenic-flexure-colonic-neoplasia
#2
Marc Beisani, Francesc Vallribera, Albert García, Laura Mora, Sebastiano Biondo, Jaime Lopez-Borao, Ramon Farrés, Júlia Gil, Eloy Espin
BACKGROUND: Optimal elective surgical treatment for splenic flexure neoplasm (SFN) is unclear. Subtotal colectomy (STC) and left hemicolectomy (LHC) are the two more common strategies used. METHODS: Observational multicentric study comparing postoperative morbidity, mortality and long-term survival on patients with SFN electively operated by STC versus LHC between 2003 and 2014. RESULTS: After revision of the databases, 144 patients were included (STC group, n = 68; LHC group, n = 76)...
July 8, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28699131/-pancreas-compressionless-gastrectomy-a-novel-laparoscopic-approach-for-suprapancreatic-lymph-node-dissection
#3
Masahiro Tsujiura, Naoki Hiki, Manabu Ohashi, Souya Nunobe, Koshi Kumagai, Satoshi Ida, Yasuhiro Okumura, Takeshi Sano, Toshiharu Yamaguchi
BACKGROUND: In radical operations for gastric cancer, a balance between the quality of lymph node dissection and safety of surgery must be ensured. During suprapancreatic lymphadenectomy in laparoscopic gastrectomy (LG), an adequate operative field should be safely and effectively established to reduce pancreas-related complications. We present a novel approach that avoids direct compression of the pancreas in LG and describe the surgical outcomes of this method. METHODS: We historically compressed the pancreas during suprapancreatic lymph node dissection in LG to obtain an adequate operative field but have since modified our operative technique...
July 11, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28684599/il-23-restoration-of-th17-effector-function-is-independent-of-il-6-and-tgf-%C3%AE-in-a-mouse-model-of-alcohol-and-burn-injury
#4
Xiaoling Li, Abigail R Cannon, Adam M Hammer, Niya L Morris, Mashkoor A Choudhry
T cells play a critical role in host defense against intestinal bacteria. We have shown that ethanol combined with burn injury suppresses Peyer's patch (PP) Th17 cytokines 1 d after injury. We assessed the mechanism of suppressed Th17 effector functions. Mice were gavaged with ethanol 4 h before burn injury and euthanized 1, 3, and 7 d after injury. Mesenteric lymph nodes (MLNs), PPs, and spleen Th1 and Th17 cytokines were assessed. A significant decrease in IL-17, IL-22, IL-2, and IFN-γ were observed in all 3 lymphoid organs 1 and 3 d after injury...
July 6, 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/28678754/impact-of-splenic-hilar-lymph-node-metastasis-on-prognosis-in-patients-with-advanced-gastric-cancer
#5
Taeil Son, In Gyu Kwon, Joong Ho Lee, Youn Young Choi, Hyoung-Il Kim, Jae-Ho Cheong, Sung Hoon Noh, Woo Jin Hyung
BACKGROUND: Impact of splenic hilar LN dissection during total gastrectomy for proximal advanced gastric cancer is controversial. The objective of this study was to assess the impact on prognosis of splenic hilar lymph node(LN) metastasis compared to that of metastasis to other regional LN groups. STUDY DESIGN: Patients who underwent total gastrectomy with D2 LN dissection from 2000 to 2010 were reviewed retrospectively. The clinicopathologic characteristics and long-term results of patients with splenic hilar LN metastasis were compared to those of patients with only metastasis to other extraperigastric LNs (stations #8a, #9, #11, or #12a)...
June 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28670989/-sudden-cardiac-death-due-to-sarcoidosis-case-report
#6
István Sejben, Zoltán Som, Gábor Cserni
Sarcoidosis is a systemic granulomatous disease of unknown aetiology, which is characterized by bilateral hilar lymphadenopathy and pulmonary disease. Clinically detected cardiac involvement occurs in 5% of sarcoid patients, although cardiac manifestations are discovered in 25% of the cases at autopsy. Sarcoid heart disease frequently causes atrioventricular block. The authors present the case of a 44-year-old man with bradycardia. On admission, second degree Mobitz II, then third degree atrioventricular block was diagnosed...
July 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28670241/beh%C3%A3-et-s-disease-with-multiple-splenic-abscesses-in-a-child
#7
Kyung In Lim, Dong Hwa Yang, Eell Ryoo
We report the case of a 5-year-old male patient with multiple aseptic splenic abscesses associated with Behçet's disease. The patient visited Gachon University Gil Hospital with fever, abdominal pain, and acute watery and bloody diarrhea, and reported a 2-year history of chronic abdominal pain and intermittent watery diarrhea. He was treated with antibiotics at a local clinic for fever and cervical lymph node swelling. Additionally, he had recurrent stomatitis. A colonoscopy showed multiple well-demarcated ulcerations throughout the colon, and abdominal computed tomography showed multiple splenic abscesses...
July 2017: Intestinal Research
https://www.readbyqxmd.com/read/28653001/follicular-dendritic-cell-sarcoma-of-the-liver-with-metachronous-small-bowel-and-splenic-metastases-a-case-report-and-literature-review
#8
Ken Min Chin, Woon Yang Ho, Kiat Hon Tony Lim, Yaw Fui Alexander Chung, Ser Yee Lee
Follicular dendritic cell sarcoma (FDCS) of the liver is an extremely rare disease, accounting for a mere 0.4% of all soft tissue sarcomas. FDCS most commonly involves lymph nodes but also affects extranodal sites such as the gastrointestinal system, oral cavity, liver, spleen and pancreas, albeit less commonly. It is widely considered a low-to-intermediate grade malignancy. We report a case of FDCS with metachronous involvement of the liver, small intestines and spleen, its imaging, histological findings and its management...
June 2017: Hepatobiliary Surgery and Nutrition
https://www.readbyqxmd.com/read/28643309/-comparison-of-clinicopathological-features-and-prognosis-between-left-sided-colon-cancer-and-right-sided-colon-cancer
#9
Xianhua Gao, Guanyu Yu, Peng Liu, Liqiang Hao, Lianjie Liu, Wei Zhang
OBJECTIVE: To compare the clinicopathological features and prognosis between left-sided colon cancer (LC) and right-sided colon cancer (RC). METHODS: Clinicopathological and follow-up data of 2 174 colon carcinoma cases undergoing resection at Shanghai Changhai Hospital of The Second Military Medical University from January 2000 to December 2010 were retrospectively analyzed. Patients with transverse colon cancer, overlapping position, unknown location, recurrent cancer, multiple primary cancer, concomitant malignant tumors, preoperative chemotherapy, local resection, incomplete clinical data and missed follow up were excluded...
June 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28642818/nivolumab-as-salvage-treatment-in-a-patient-with-hiv-related-relapsed-refractory-hodgkin-lymphoma-and-liver-failure-with-encephalopathy
#10
Jose D Sandoval-Sus, Francis Mogollon-Duffo, Ankita Patel, Nathan Visweshwar, Damian A Laber, Richard Kim, Michael V Jagal
BACKGROUND: We report the first case to our knowledge of a patient with relapsed/refractory classical hodgkin lymphoma and liver failure with encephalopathy along with human immunodeficiency virus/acquired immunodeficiency syndrome infection, successfully treated with nivolumab without major side effects and encouraging prolonged disease control. CASE PRESENTATION: In December 2015, at the time of the patient's progression from his Hodgkin lymphoma after fourth line treatment, he developed persistent fevers, abdominal distension, jaundice and worsening of his liver function tests...
2017: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/28620954/propentofylline-phosphodiesterase-and-adenosine-reuptake-inhibitor-modulates-lymphocyte-subsets-and-lymphocyte-activity-after-in-vivo-administration-in-non-immunized-and-srbc-immunized-mice
#11
Marianna Szczypka, Magdalena Lis, Agnieszka Suszko-Pawłowska, Aleksandra Pawlak, Angelika Sysak, Bożena Obmińska-Mrukowicz
OBJECTIVES: The aim of the study was to investigate immunomodulatory effect of in-vivo administered propentofylline on the subsets and activity of murine lymphocytes. METHODS: Propentofylline (3 mg/kg) was administered orally to 8-week-old Balb/c mice, once or six times at 12-h intervals. The lymphocyte subsets, regulatory T cells, IL-5 and TNF levels were determined 12 h and 24 h after a single dose or after the sixth dose of the drug in non-immunized mice. Humoral immune response in sheep red blood cells (SRBC)-immunized mice was determined 4, 7 and 14 days after immunization...
June 16, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28616609/three-dimensional-computed-tomography-simulation-for-laparoscopic-lymph-node-dissection-in-the-treatment-of-proximal-gastric-cancer
#12
REVIEW
Hideki Sunagawa, Takahiro Kinoshita
Application of laparoscopic surgery (LS) has expanded worldwide in the various fields due to the potential advantage of being less invasive than open surgery; however difficulty in recognizing positional relationship of the organs is one of the disadvantages of this kind of surgery. In order to compensate this drawback, preoperative three-dimensional computed tomography (3D-CT) simulation is regarded as promising. In gastric cancer surgery, 3D-CT simulation seems particularly effective in the splenic hilar dissection, because this region is associated with remarkable anatomical variation with complexity...
2017: Translational Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28616599/current-status-and-future-perspectives-of-laparoscopic-radical-surgery-for-advanced-gastric-cancer
#13
REVIEW
Takahiro Kinoshita, Akio Kaito
Laparoscopic radical gastrectomy with lymph node dissection has widely penetrated to East Asian countries, where incidence of gastric cancer occurrence is higher than the rest of the world. Laparoscopic distal gastrectomy for cStageI disease is regarded as one of the option in daily practice in the latest Japanese guidelines; however its applicability to more advanced disease (Stage II/III) is still under debate. Actually, operative techniques of laparoscopic D2 dissection is being matured, but still, necessity of total omentectomy, splenic hilar dissection, management of bulky nodes or large primary tumor, high-level anastomosis in esophageal invasion cases, and extensive peritoneal lavage can be raised as technical limitations...
2017: Translational Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28603942/primary-hepatic-choriocarcinoma-in-an-83-year-old-woman
#14
Akihiko Fukagawa, Naoto Fujita, Kenji Ohira, Hajime Fujimoto, Nobuaki Goto, Akinori Nozawa
We present a case of primary hepatic choriocarcinoma in an 83-year-old Japanese woman with gastric wall and lymph node metastases and a splenic vein tumor thrombus. Multiple irregular hepatic tumors with massive necrosis and hemorrhage were observed during autopsy. Syncytiotrophoblast-like and mononucleated cytotrophoblast-like cell morphology with focal hepatocellular carcinoma (HCC)-like trabecular structures was observed. In immunohistochemical analyses, the tumor cells expressed human chorionic gonadotropin (hCG) and cytokeratins (AE1/AE3, CK7, CK19) but were negative for alpha-fetoprotein (AFP), glypican-3, and vimentin...
June 11, 2017: Pathology International
https://www.readbyqxmd.com/read/28587972/salvage-photodynamic-therapy-accompanied-by-extended-lymphadenectomy-for-advanced-esophageal-carcinoma-a-case-report
#15
Takahiro Nishida, Shinsuke Takeno, Koji Nakashima, Masato Kariya, Haruhiko Inatsu, Kazuo Kitamura, Atsushi Nanashima
INTRODUCTION: Salvage surgery for locoregional failures after definitive chemoradiotherapy (dCRT) for esophageal cancer is widely practiced, but treatment options complementing it are also needed due to the high morbidity and mortality and low rate of curative resection. PRESENTATION OF CASE: A 58-year-old man with a surgical history of right upper lobectomy for lung cancer was diagnosed as having esophageal squamous cell carcinoma. Computed tomography revealed swelling of the lesser curvature lymph node, and it had invaded the stomach, the body and tail of the pancreas and the left gastric artery, splenic artery and celiac artery...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28587425/bathing-effects-of-east-saline-groundwater-concentrates-on-allergic-atopic-dermatitis-like-skin-lesions-induced-by-2-4-dinitrochlorobenzene-in-hairless-mice
#16
Choong-Gon Kim, Ji-Eun Lee, Da-Geum Jeong, Youn-Ho Lee, Sang-In Park, Dae-Geon Lee, Chang-Hyun Han, Su-Jin Kang, Chang-Hyun Song, Seong-Hun Choi, Young-Joon Lee, Sae-Kwang Ku
In the present study, it was evaluated whether east saline groundwater concentration solution (ESGWc) exerted a favorable inhibitory effect on 2,4-dinitrochlorobenzene (DNCB)-induced allergic/atopic-like dermatitis (AD). AD was induced and boosted by sensitization with DNCB via topical application on the dorsal back skins. Mice with DNCB-induced AD were bathed in 100-, 200- and 400-fold diluted ESGWc. After 6 weeks bathing, changes to body weight, clinical skin severity scores, scratching behavior, serum total immunoglobulin (Ig)E levels, submandibular lymph node and spleen weights, splenic cytokine levels, skin cytokine mRNA expressions, antioxidant defense systems and superoxide anion productions were recorded to determine the effects of bathing on the histopathology of dorsal back skin tissues...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28577727/spleen-preserving-lymphadenectomy-versus-splenectomy-in-laparoscopic-total-gastrectomy-for-advanced-gastric-cancer
#17
Sang-Yong Son, Dong Joon Shin, Young Suk Park, Aung Myint Oo, Do-Hyun Jung, Chang Min Lee, Sang-Hoon Ahn, Do Joong Park, Hyung-Ho Kim
BACKGROUND: To investigate the optimal approach for laparoscopic splenic hilum lymph node dissection in proximal advanced gastric cancer, we compared the operative outcomes between laparoscopic spleen-preserving total gastrectomy (sp-LTG) and laparoscopic total gastrectomy with splenectomy (sr-LTG). METHODS: A retrospective case-cohort study was conducted between February 2006 and December 2012. The operative outcomes, the number of retrieved splenic hilum lymph node, complication, and patients' survivals were analyzed...
June 2017: Surgical Oncology
https://www.readbyqxmd.com/read/28577652/splenic-marginal-zone-lymphoma-a-literature-review-of-diagnostic-and-therapeutic-challenges
#18
Tayse Silva Dos Santos, Renato Sampaio Tavares, Danielle Leão Cordeiro de Farias
Splenic marginal zone lymphoma (SMZL) is a low-grade B-cell non-Hodgkin's lymphoma characterized by massive splenomegaly, moderate lymphocytosis with or without villous lymphocytes, rare involvement of peripheral lymph nodes and indolent clinical course. As a rare disease, with no randomized prospective trials, there is no standard of care for SMZL so far. Splenectomy has been done for many years as an attempt to control disease, but nowadays it has not been encouraged as first line because of new advances in therapy as rituximab, that are as effective with minimal toxicity...
April 2017: Revista Brasileira de Hematologia e Hemoterapia
https://www.readbyqxmd.com/read/28566677/high-grade-transformation-in-a-splenic-marginal-zone-lymphoma-with-a-cerebral-manifestation
#19
Xiaoning Gao, Jie Li, Ji Lin, Daihong Liu, Li Yu, Quanshun Wang
BACKGROUND Splenic marginal zone lymphomas (SMZLs) are generally uncommon, indolent lymphomas that typically affect older adults, but the development of the transformation to high-grade lymphoma may occur in a small proportion of patients and represents a rare event with blastic cell infiltration in the lymph nodes and bone marrow. CASE REPORT Here, we present a young adult patient who was diagnosed with a SMZL and developed a high-grade transformation to diffuse large B cell lymphoma (DLBCL) with central nervous system involvement...
June 1, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28521786/role-of-routine-abdominal-ultrasonography-in-intensified-tuberculosis-case-finding-algorithms-at-hiv-clinics-in-high-tb-burden-settings
#20
Sonam Spalgais, Upasna Agarwal, Rohit Sarin, Devesh Chauhan, Anita Yadav, Anand Jaiswal
BACKGROUND: High proportion of TB in people living with HIV (PLHIV) is undiagnosed. Due to this active TB case finding is recommended for HIV clinics in high TB burden countries. Presently sputum examination and chest radiography are frontline tests recommended for HIV infected TB presumptives. Abdominal TB which occurs frequently in PLHIV may be missed even by existing programmatic intensified case finding protocols. This study evaluated the routine use of ultrasonography (USG) for active case finding of abdominal TB in HIV clinics...
May 18, 2017: BMC Infectious Diseases
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