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https://www.readbyqxmd.com/read/27921157/assessment-of-pisotriquetral-misalignment-with-magnetic-resonance-imaging-is-it-associated-with-trauma
#1
Hee-Dong Chae, Hye Jin Yoo, Sung Hwan Hong, Ja-Young Choi, Heung Sik Kang
OBJECTIVE: Our objective was to determine whether there is an association between pisotriquetral (PT) malalignment and acute distal radius fracture by using magnetic resonance imaging (MRI). METHODS: We evaluated 138 patients who underwent 3-T MRI of the wrists. Group A comprised 85 patients with acute distal radius fracture, and group B comprised 53 patients without trauma. PT interval and angle and pisiform excursion were measured on oblique axial and sagittal multiplanar reformats...
December 5, 2016: European Radiology
https://www.readbyqxmd.com/read/27890427/internal-and-external-generalizability-of-temporal-dose-response-relationships-for-xerostomia-following-imrt-for-head-and-neck-cancer
#2
Maria Thor, Adepitan A Owosho, Haley D Clark, Jung Hun Oh, Nadeem Riaz, Allan Hovan, Jillian Tsai, Steven D Thomas, Sae Hee K Yom, Jonn S Wu, Joseph M Huryn, Vitali Moiseenko, Nancy Y Lee, Cherry L Estilo, Joseph O Deasy
BACKGROUND AND PURPOSE: To study internal and external generalizability of temporal dose-response relationships for xerostomia after intensity-modulated radiotherapy (IMRT) for head and neck cancer, and to investigate potential amendments of the QUANTEC guidelines. MATERIAL AND METHODS: Objective xerostomia was assessed in 121 patients (nCohort1=55; nCohort2=66) treated to 70Gy@2Gy in 2006-2015. Univariate and multivariate analyses (UVA, MVA with 1000 bootstrap populations) were conducted in Cohort1, and generalizability of the best-performing MVA model was investigated in Cohort2 (performance: AUC, p-values, and Hosmer-Lemeshow p-values (pHL))...
November 24, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27863036/newborn-hearing-screening-in-prematurity-fate-of-screening-failures-and-auditory-maturation
#3
Hyung Chae Yang, Chung Man Sung, Dong Joo Shin, Yong Beom Cho, Chul Ho Jang, Hyong-Ho Cho
OBJECTIVES: The purpose of this study was to identify delayed auditory maturation and the fate of premature infants who failed the newborn hearing screening (NHS) in neonatal intensive care unit. MATERIALS AND METHODS: A total of 1,375 neonates underwent NHS using the transient evoked otoacoustic emission (TEOAE) in a tertiary hospital between 2007 and 2010 according to the Joint Committee on Infant Hearing Guidelines. In addition, a structured telephone survey was given to caregivers of infants who were lost to follow-up NHS...
November 12, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27861391/effect-of-age-and-sex-on-retinal-layer-thickness-and-volume-in-normal-eyes
#4
Jae Yon Won, Sung Eun Kim, Young-Hoon Park
The aim of the study was to evaluate the effect of sex and age on the thickness of the retinal layer in normal eyes using spectral-domain optical coherence tomography (SD-OCT).Fifty healthy subjects between the ages of 20 and 80 had their retinal layers measured using SD-OCT at Seoul St. Mary's Hospital. Mean thickness and volume were measured for 9 retinal layers in the fovea, the pericentral ring, and the peripheral ring. The differences of sex- and age-related thickness and volume in each retinal layer were analyzed...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27773851/intradermal-grass-pollen-immunotherapy-increases-th2-and-ige-responses-and-worsens-respiratory-allergic-symptoms
#5
Anna Slovick, Abdel Douiri, Rachel Muir, Andrea Guerra, Konstantinos Tsioulos, Evie Hay, Emily P S Lam, Joanna Kelly, Janet L Peacock, Sun Ying, Mohamed H Shamji, David J Cousins, Stephen R Durham, Stephen J Till
BACKGROUND: Repeated low-dose grass pollen intradermal allergen injection suppresses allergen-induced cutaneous late-phase responses comparably with conventional subcutaneous and sublingual immunotherapy. OBJECTIVE: We sought to evaluate the efficacy and safety of grass pollen intradermal immunotherapy in the treatment of allergic rhinitis. METHODS: We randomly assigned 93 adults with grass pollen-induced allergic rhinitis to receive 7 preseasonal intradermal allergen injections (containing 7 ng of Phl p 5 major allergen) or a histamine control...
October 20, 2016: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27763856/relevance-of-allergenic-sensitization-to-cynodon-dactylon-and-phragmites-communis-cross-reactivity-with-pooideae-grasses
#6
M A López-Matas, R Moya, V Cardona, A Valero, P Gaig, A Malet, M Viñas, A García-Moral, M Labrador, E Alcoceba, M Ibero, J Carnés
BACKGROUND AND OBJECTIVES: The homologous group of sweet grasses belongs to the Pooideae subfamily, but grass pollen species from other subfamilies can also cause allergy, such as Cynodon dactylon (Chloridoideae) and Phragmites communis (Arundinoideae). C dactylon and P communis have not been included in the sweet grasses homologous group because of their low cross-reactivity with other grasses. The aims of this study were to investigate the profile of sensitization to C dactylon and P communis in patients sensitized to grasses and to analyze cross-reactivity between these 2 species and temperate grasses...
2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27753449/cross-sectional-study-on-allergic-sensitization-of-austrian-adolescents-using-molecule-based-ige-profiling
#7
Teresa Stemeseder, Eva Klinglmayr, Stephanie Moser, Lisa Lueftenegger, Roland Lang, Martin Himly, Gertie J Oostingh, Joerg Zumbach, Arne C Bathke, Thomas Hawranek, Gabriele Gadermaier
BACKGROUND: Allergen specific IgE antibodies are a hallmark of type I allergy. The aim of this cross-sectional study was to analyze the sensitization profiles of an Austrian adolescent population utilizing molecule-based IgE diagnosis. METHODS: Serum samples of 501 non-selected pupils from Salzburg, Austria, were tested in ImmunoCAP ISAC(®) for IgE reactivity to 112 single allergens. Sensitization profiles were assessed and statistically coordinated with reported allergies...
October 18, 2016: Allergy
https://www.readbyqxmd.com/read/27746888/primary-hepatic-lymphoma-a-retrospective-multicenter-rare-cancer-network-study
#8
Gamze Ugurluer, Robert C Miller, Yexiong Li, Juliette Thariat, Pirus Ghadjar, Ulrike Schick, Mahmut Ozsahin
Primary hepatic lymphoma (PHL) is a rare malignancy. We aimed to assess the clinical profile, outcome and prognostic factors in PHL through the Rare Cancer Network (RCN). A retrospective analysis of 41 patients was performed. Median age was 62 years (range, 23-86 years) with a male-to-female ratio of 1.9:1.0. Abdominal pain or discomfort was the most common presenting symptom. Regarding B-symptoms, 19.5% of patients had fever, 17.1% weight loss, and 9.8% night sweats. The most common radiological presentation was multiple lesions...
September 5, 2016: Rare Tumors
https://www.readbyqxmd.com/read/27718314/the-assessment-of-data-sources-for-influenza-virologic-surveillance-in-new-york-state
#9
Kay L Escuyer, Christine L Waters, Donna L Gowie, Angie M Maxted, Gregory M Farrell, Meghan E Fuschino, Kirsten St George
BACKGROUND: Following the 2013 USA release of the Influenza Virologic Surveillance Right Size Roadmap, the New York State Department of Health (NYSDOH) embarked on an evaluation of data sources for influenza virologic surveillance. OBJECTIVE: To assess NYS data sources, additional to data generated by the state public health laboratory (PHL), which could enhance influenza surveillance at the state and national level. METHODS: Potential sources of laboratory test data for influenza were analyzed for quantity and quality...
October 8, 2016: Influenza and Other Respiratory Viruses
https://www.readbyqxmd.com/read/27639783/nitration-of-pollen-aeroallergens-by-nitrate-ion-in-conditions-simulating-the-liquid-water-phase-of-atmospheric-particles
#10
Alessandra Ghiani, Maurizio Bruschi, Sandra Citterio, Ezio Bolzacchini, Luca Ferrero, Giorgia Sangiorgi, Riccardo Asero, Maria Grazia Perrone
Pollen aeroallergens are present in atmospheric particulate matter (PM) where they can be found in coarse biological particles such as pollen grains (aerodynamic diameter dae>10μm), as well as fragments in the finest respirable particles (PM2.5; dae<2.5μm). Nitration of tyrosine residues in pollen allergenic proteins can occur in polluted air, and inhalation and deposition of these nitrated proteins in the human respiratory tract may lead to adverse health effects by enhancing the allergic response in population...
December 15, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27614266/major-grass-pollen-allergens-and-components-detected-in-a-southern-chinese-cohort-of-patients-with-allergic-rhinitis-and-or-asthma
#11
Wenting Luo, Huimin Huang, Peiyan Zheng, Nili Wei, Jiaying Luo, Baoqing Sun, Guangqiao Zeng
There is so far a paucity of data about allergen component-resolved diagnosis, and the prevalence of grass pollen allergen components in China, in contrast to those from western countries. Even in this country, allergies to grass pollen allergen components in the vast south are inadequately described. This study aimed to determine the major sensitizing grass pollens in Guangzhou, the largest city in Guangdong province of southern China. Included in this study were 258 patients having allergic rhinitis with or without asthma and 88 healthy controls...
October 2016: Molecular Immunology
https://www.readbyqxmd.com/read/27605018/liposomes-containing-gadodiamide-preparation-physicochemical-characterization-and-in-vitro-cytotoxic-evaluation
#12
Ana Luiza Chaves Maia, Christian Fernandes, Cynthia Nara Pereira de Oliveira, Claudia Salviano Teixeira, Mariana Silva Oliveira, Daniel Cristian Soares, Gilson Andrade Ramaldes
The aim of this study was develop, characterize and assess the cytotoxic activity of pH-sensitive (pHL-Gd), stealth pH-sensitive (SpHL-Gd), and conventional (convL-Gd) liposomes containing gadodiamide (Gd-DTPA-BMA). Formulations were prepared by reverse-phase evaporation method and their physicochemical properties were evaluated by means of particle size, zeta potential, and Gd-DTPA- BMA entrapment. SpHL-Gd was considered the most promising liposome, since it combines stealth and fusogenic characteristics that can contribute for higher therapeutic efficiency...
September 6, 2016: Current Drug Delivery
https://www.readbyqxmd.com/read/27588729/the-clinical-relevance-of-birch-pollen-profilin-cross-reactivity-in-sensitized-patients
#13
Florian Wölbing, Julia Kunz, Wolfgang Eberhard Kempf, Cornelia Grimmel, Jörg Fischer, Tilo Biedermann
BACKGROUND: Overlapping seasons and cross reactivity, especially to grass pollen profilin, can hamper the diagnosis of birch pollen allergy. To identify the primary sensitizing allergen and the clinical relevance of cross sensitization, we correlated sensitization profiles with in vitro and in vivo tests, symptom scores and pollen counts. METHODS: 433 patients with positive skin prick test (SPT) to birch pollen were analyzed regarding IgE to major birch and grass pollen allergens Bet v 1 and Phl p 1/p 5 and the profilins Bet v 2 and Phl p 12...
September 2, 2016: Allergy
https://www.readbyqxmd.com/read/27553435/prognostic-factors-from-a-randomized-phase-iii-trial-of-paclitaxel-and-carboplatin-versus-paclitaxel-and-cisplatin-in-metastatic-or-recurrent-cervical-cancer-japan-clinical-oncology-group-jcog-trial-jcog0505-s1
#14
Shin Nishio, Ryo Kitagawa, Taro Shibata, Hiroyuki Yoshikawa, Ikuo Konishi, Kimio Ushijima, Toshiharu Kamura
PURPOSE: The Japan Clinical Oncology Group (JCOG) trial JCOG0505 demonstrated the statistically significant non-inferiority of paclitaxel plus carboplatin (TC) to paclitaxel plus cisplatin (TP) in terms of overall survival (OS) in metastatic or recurrent cervical cancer. In that trial, patients were randomly assigned, adjusting for institution and known prognostic factors. The objective of this ancillary study was to evaluate the appropriateness of the adjustment factors used to have randomly assigned treatments and to investigate new potentially useful prognostic factors of paclitaxel plus platinum for future randomized trials in metastatic or recurrent cervical cancer...
October 2016: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/27445696/allergy-enhances-neurogenesis-and-modulates-microglial-activation-in-the-hippocampus
#15
Barbara Klein, Heike Mrowetz, Josef Thalhamer, Sandra Scheiblhofer, Richard Weiss, Ludwig Aigner
Allergies and their characteristic TH2-polarized inflammatory reactions affect a substantial part of the population. Since there is increasing evidence that the immune system modulates plasticity and function of the central nervous system (CNS), we investigated the effects of allergic lung inflammation on the hippocampus-a region of cellular plasticity in the adult brain. The focus of the present study was on microglia, the resident immune cells of the CNS, and on hippocampal neurogenesis, i.e., the generation of new neurons...
2016: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/27394999/acidification-of-prehydrolysis-liquor-and-spent-liquor-of-neutral-sulfite-semichemical-pulping-process
#16
Pedram Fatehi, Weijiue Gao, Yonghui Sun, Mehdi Dashtban
Acidification has been commercialized for producing kraft lignin from black liquor of kraft pulping process. This work intended to evaluate the effectiveness of acidification in extracting lignocelluloses from the spent liquor of neutral sulfite semichemical pulping (NSSC) process and from prehydrolysis liquor (PHL) of kraft-based dissolving pulp production process. The results showed that the NSSC and PHL spent liquors had some lignin-carbohydrate complexes (LCC), and that the square weighted counts of particles with a chord length of 50-150μm in the spent liquors were significantly increased as pH dropped to 1...
October 2016: Bioresource Technology
https://www.readbyqxmd.com/read/27375902/molecular-and-growth-based-drug-susceptibility-testing-of-mycobacterium-tuberculosis-complex-for-ethambutol-resistance-in-the-united-states
#17
Mitchell A Yakrus, Jeffrey Driscoll, Allison McAlister, David Sikes, Denise Hartline, Beverly Metchock, Angela M Starks
Ethambutol (EMB) is used as a part of drug regimens for treatment of tuberculosis (TB). Susceptibility of Mycobacterium tuberculosis complex (MTBC) isolates to EMB can be discerned by DNA sequencing to detect mutations in the embB gene associated with resistance. US Public Health Laboratories (PHL) primarily use growth-based drug susceptibility test (DST) methods to determine EMB resistance. The Centers for Disease Control and Prevention (CDC) provides a service for molecular detection of drug resistance (MDDR) by DNA sequencing and concurrent growth-based DST using agar proportion...
2016: Tuberculosis Research and Treatment
https://www.readbyqxmd.com/read/27374125/relevance-of-allergenic-sensitization-to-cynodon-dactylon-and-phragmites-communis-cross-reactivity-with-the-pooideae-grasses
#18
M A López-Matas, R Moya, V Cardona, A Valero, P Gaig, A Malet, M Viñas, A García-Moral, M Labrador, E Alcoceba, M Ibero, J Carnés
BACKGROUND: Besides the Pooideae sub-family of grasses, there are other sub-families with allergenic members such as Cynodon dactylon (Chloridoideae) or Phragmites communis (Arundinoideae). Pooideae species belong to the same homologous group (sweet grasses). C. dactylon and P. communis are not included in this group because cross-reactivity with other grasses is not significant. OBJECTIVES: The objectives were to investigate the sensitization profile to C. dactylon and P...
April 11, 2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27368165/thylakoid-membrane-model-of-the-chl-a-fluorescence-transient-and-p700-induction-kinetics-in-plant-leaves
#19
N E Belyaeva, A A Bulychev, G Yu Riznichenko, A B Rubin
A new Thylakoid model is presented, which describes in detail the electron/proton transfer reactions between membrane protein complexes including photosystems II and I (PSII, PSI), cytochrome (Cyt) b 6 f, mobile plastoquinone PQ pool in the thylakoid membrane, plastocyanin in lumen and ferredoxin in stroma, reduction of NADP via FNR and cyclic electron transfer. The Thylakoid model parameters were fitted both to Chl fluorescence induction data (FI) and oxido-reductions of P700 (ΔA 810) measured from 20 μs up to 20 s in pea leaves...
July 1, 2016: Photosynthesis Research
https://www.readbyqxmd.com/read/27358726/influence-of-profilin-on-sensitisation-profiles-determined-by-cutaneous-tests-and-ige-to-major-allergens-in-polysensitised-patients
#20
Nieves Segura, Teresa Abos, José A Compaired, Esther Compés, Isabel Guallar, Manuel Morales, Susana Monzón, José Mozota, Pilar Muñoz, Jesús Pola, Macarena Quintana, Beatriz Rojas, Sara San Juan, Felicitas Villa, Cristina Zapata, Lucía Jimeno, Fernando de la Torre
BACKGROUND: Profilin sensitisation is considered a diagnostic confounding factor in areas where patients are exposed to multiple pollens. The aim of this study is to assess pollen sensitisation profiles in adults and children and to evaluate, by means of component-resolved diagnosis (CRD) and skin prick testing (SPT), which pollens may be considered as risk factors of profilin sensitisation in order to establish the best diagnostic approach in polysensitised patients. METHODS: A total of 231 pollen-allergic patients (adults and children) were included, out of the pollen season, from an area with similar levels of pollen exposure...
2016: Clinical and Translational Allergy
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