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Anatomical segmentation

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https://www.readbyqxmd.com/read/28527188/optimum-pure-intrusion-of-a-mandibular-canine-with-the-segmented-arch-in-lingual-orthodontics
#1
Abhishek M Thote, Krishna Sharma, Rashmi V Uddanwadiker, Sunita Shrivastava
BACKGROUND: Approximately 50% patients with a deep bite possess anatomically extruded mandibular canines. OBJECTIVE: The objective of this study was to specify an optimum toe (Θ) of the vertical segment of a cantilever from the distal aspect to achieve pure intrusion of a mandibular canine with the segmented arch in lingual orthodontics (LiO). METHODS: The geometrical model of a mandibular canine was developed to compute the required values of Θ (positive values - toe-in, negative values - toe-out)...
2017: Bio-medical Materials and Engineering
https://www.readbyqxmd.com/read/28526212/3d-deeply-supervised-network-for-automated-segmentation-of-volumetric-medical-images
#2
Qi Dou, Lequan Yu, Hao Chen, Yueming Jin, Xin Yang, Jing Qin, Pheng-Ann Heng
While deep convolutional neural networks (CNNs) have achieved remarkable success in 2D medical image segmentation, it is still a difficult task for CNNs to segment important organs or structures from 3D medical images owing to several mutually affected challenges, including the complicated anatomical environments in volumetric images, optimization difficulties of 3D networks and inadequacy of training samples. In this paper, we present a novel and efficient 3D fully convolutional network equipped with a 3D deep supervision mechanism to comprehensively address these challenges; we call it 3D DSN...
May 8, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28523339/medial-meniscal-extrusion-a-validation-study-comparing-different-methods-of-assessment
#3
Luke D Jones, Stephen J Mellon, Neil Kruger, Andrew P Monk, Andrew J Price, David J Beard
PURPOSE: Longitudinal cohort studies of knee OA aetiology use MRI to assess meniscal extrusion within the same knee at sequential time points. A validated method of assessment is required to ensure that extrusion is measured at the same location within the knee at each time point. Absolute perpendicular extrusion from the tibial edge can be assessed using the reference standard of segmentation of the tibia and medial meniscus. This is labour intensive and unsuitable for large cohorts...
April 21, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28522735/d3-receptors-regulate-excitability-in-a-unique-class-of-prefrontal-pyramidal-cell
#4
Rebecca L Clarkson, Alayna T Liptak, Steven M Gee, Vikaas S Sohal, Kevin J Bender
The D3 dopamine receptor, a member of the Gi-coupled D2-family of dopamine receptors, is expressed throughout limbic circuits affected in neuropsychiatric disorders, including prefrontal cortex. These receptors are important for prefrontal executive function, as pharmacological and genetic manipulations that affect prefrontal D3 receptors alter anxiety, social interaction, and reversal learning. And yet, the mechanisms by which D3 receptors regulate prefrontal circuits, and whether D3 receptors regulate specific prefrontal subnetworks, remain unknown...
May 17, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28521360/exposure-of-the-external-carotid-artery-through-the-posterior-triangle-of-the-neck-a-novel-approach-to-facilitate-bypass-procedures-to-the-posterior-cerebral-circulation
#5
Ali Tayebi Meybodi, Michael T Lawton, Pooneh Mokhtari, Olivia Kola, Ivan H El-Sayed, Arnau Benet
BACKGROUND: The external carotid artery (ECA) is the main high-flow donor for extracranial-intracranial revascularization procedures. However, anatomic restraints limit the availability of ECA in posterior exposures of the craniocervical junction aimed for bypass to distal vertebral artery segments. OBJECTIVE: To examine the feasibility and safety of exposure of the ECA through the posterior triangle of the neck. METHODS: A preliminary feasibility study on the posterior neck exposure of the ECA was performed in 1 cadaveric head (2 sides) followed by a morphometric study on 9 cadaveric heads (18 sides)...
June 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28521347/sequential-extradural-release-of-the-v3-vertebral-artery-to-facilitate-intradural-v4-vertebral-artery-reanastomosis-feasibility-of-a-novel-revascularization-technique
#6
Ali Tayebi Meybodi, Michael T Lawton, Arnau Benet
BACKGROUND: Revascularization of the intradural vertebral artery (VA) usually involves V3-V4 bypass using an interposition graft. The interposition of a graft increases surgical time, adds risks, and requires 2 suture lines. OBJECTIVE: To assess the feasibility of an excision-reanastomosis of V4 by sequentially releasing V3. METHODS: Twenty specimens were prepared for surgical simulation of a far-lateral approach. The third and fourth segments of the VA were exposed through the far-lateral approach bilaterally...
June 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28520651/laparoscopic-management-of-hepatocellular-carcinoma-a-critical-reappraisal
#7
David Fuks, Luca Aldrighetti, Long R Jiao, Go Wakabayashi, Paolo Limongelli
Following the introduction of the first laparoscopic liver resection, after ∼25 years, a critical reappraisal seems to be warranted. Liver resection represents the first choice for curing early hepatocellular carcinoma (HCC) allowing a curative chance also in selected patients with intermediate stage tumors. The criteria for liver resectability by laparoscopy remains the same for open surgery, which is oncological criteria (absence of extrahepatic tumor location; completely resectable R0 resection), anatomic (resectability of involved segment with its own blood surely and biliary drainage; absence of vascular invasion of portal or hepatic veins) and technical (possibility to leave in place a residual volume ≥40%)...
May 17, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28512057/normative-morphometric-data-for-cerebral-cortical-areas-over-the-lifetime-of-the-adult-human-brain
#8
Olivier Potvin, Louis Dieumegarde, Simon Duchesne
Proper normative data of anatomical measurements of cortical regions, allowing to quantify brain abnormalities, are lacking. We developed norms for regional cortical surface areas, thicknesses, and volumes based on cross-sectional MRI scans from 2713 healthy individuals aged 18 to 94 years using 23 samples provided by 21 independent research groups. The segmentation was conducted using FreeSurfer, a widely used and freely available automated segmentation software. Models predicting regional cortical estimates of each hemisphere were produced using age, sex, estimated total intracranial volume (eTIV), scanner manufacturer, magnetic field strength, and interactions as predictors...
May 13, 2017: NeuroImage
https://www.readbyqxmd.com/read/28510777/anatomical-characterization-of-the-nasolacrimal-canal-based-on-computed-tomography-in-children-with-complex-congenital-nasolacrimal-duct-obstruction
#9
Chengyue Zhang, Gang Yu, Yanhui Cui, Qian Wu, Wenbin Wei
PURPOSE: To characterize anatomical variations of the nasolacrimal canal in patients with complex congenital nasolacrimal duct obstruction. METHODS: Retrospective case series of 25 children with congenital nasolacrimal duct obstruction. All children had failed probings and were examined by computed tomography. An analysis of imaging data is presented. RESULTS: Anomalous development of the nasolacrimal canal was confirmed on computed tomography...
May 15, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28510720/effects-of-a-3d-segmental-prosthetic-system-for-tricuspid-valve-annulus-remodelling-on-the-right-coronary-artery-a-human-cadaveric-coronary-angiography-study
#10
Mohsen Riki-Marishani, Arash Gholoobi, Ghasem Sazegar, Mathias H Aazami, Aria Hedjazi, Maryam Sajjadian, Mahmoud Ebrahimi, Ahmad Aghaii-Zade Torabi
OBJECTIVES: A prosthetic system to repair secondary tricuspid valve regurgitation was developed. The conceptual engineering of the current device is based on 3D segmental remodelling of the tricuspid valve annulus in lieu of reductive annuloplasty. This study was designed to investigate the operational safety of the current prosthetic system with regard to the anatomical integrity of the right coronary artery (RCA) in fresh cadaveric human hearts. METHODS: During the study period, from January to April 2016, the current prosthetic system was implanted on the tricuspid valve annulus in fresh cadaveric human hearts that met the study's inclusion criteria...
May 16, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28509581/dexamethasone-distribution-characteristic-following-controllable-continuous-sub-tenon-drug-delivery-in-rabbit
#11
Xuetao Huang, Manqiang Peng, Yezhen Yang, Yiqin Duan, Kuanshu Li, Shaogang Liu, Changhua Ye, Ding Lin
Drug delivery systems are required to be safe, minimally invasive and effectively delivery drug to the target tissues. But delivery drugs to the eye has not yet satisfied this need. Here, we focused on examining the distribution of dexamethasone (DEX) in ocular and plasmic samples following controllable continuous sub-Tenon drug delivery (CCSDD) of dexamethasone disodium phosphate (DEXP) in rabbit, and to compare that with two traditional routes: subconjunctival injection and intravenous injection. The DEX concentration was analyzed by Shimadzu LC-MS 2010 system...
November 2017: Drug Delivery
https://www.readbyqxmd.com/read/28509425/methods-of-fixation-of-intraocular-lenses-according-to-the-anatomical-structures-in-trauma-eyes
#12
REVIEW
Miltiadis Fiorentzis, Anja Viestenz, Jens Heichel, Berthold Seitz, Thomas Hammer, Arne Viestenz
Ocular trauma can lead to severe visual impairment and morbidity, depending on the anatomical structures affected. The main causes of ocular trauma include foreign bodies, impact by an object, falls, and chemicals. Most ocular traumas occur in children or young male adults. A meticulous slit lamp examination is crucial for assessing all anatomical structures. Trauma to the crystalline lens can result in dislocation, an intralenticular foreign body, cataract, fragmentation, and capsular breach. An intraocular lens (IOL) can endure subluxation or luxation under the conjunctiva, into the anterior chamber or the vitreous, or can be extruded...
May 16, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28508917/dowel-pinning-for-metacarpal-and-metatarsal-fractures-in-dogs
#13
Matthias Kornmayer, Ulrike Matis
OBJECTIVE: To evaluate a dowel pinning technique for metacarpal and metatarsal fractures in dogs. MATERIAL AND METHODS: Medical records of 13 dogs with complete clinical and radiographic follow-up examinations after a median observation time of 5 months were evaluated retrospectively. Assessment included fracture data, number of stabilized bones versus number of fractured bones and parameters of internal fixation including postoperative axial alignment and position of implants assessed on serial radiographs...
May 16, 2017: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/28508146/laparoscopic-parenchymal-sparing-liver-resections-using-the-intrahepatic-glissonian-approach
#14
Marcel Autran C Machado, R Surjan, T Basseres, F Makdissi
BACKGROUND: One of the main criticisms of laparoscopic liver resection is that it is difficult, or not possible, to perform liver-sparing resections. Our aim was to present short videos where the intrahepatic Glissonian approach was used to perform anatomical liver segmental resections, instead of a larger operation, to avoid unnecessary sacrifice of the liver parenchyma. METHODS: We selected six types of anatomical liver resections to exemplify the use of the intrahepatic Glissonian approach to perform segment-oriented liver resections...
May 15, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28504987/secondary-reconstruction-of-maxillofacial-trauma
#15
Jaime Castro-Núñez, Joseph E Van Sickels
PURPOSE OF REVIEW: Craniomaxillofacial trauma is one of the most complex clinical conditions in contemporary maxillofacial surgery. Vital structures and possible functional and esthetic sequelae are important considerations following this type of trauma and intervention. Despite the best efforts of the primary surgery, there are a group of patients that will have poor outcomes requiring secondary reconstruction to restore form and function. The purpose of this study is to review current concepts on secondary reconstruction to the maxillofacial complex...
May 12, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/28502377/long-term-follow-up-of-patients-undergoing-autologous-noncultured-melanocyte-keratinocyte-transplantation-for-vitiligo-and-other-leukodermas
#16
Narumol Silpa-Archa, James L Griffith, Richard H Huggins, Marsha D Henderson, Holly A Kerr, Gordon Jacobsen, Sanjeev V Mulekar, Henry W Lim, Iltefat H Hamzavi
BACKGROUND: Persistence of pigmentation after a melanocyte-keratinocyte transplantation procedure (MKTP) is an important consideration for efficacy. OBJECTIVE: We sought to determine long-term repigmentation of MKTP in vitiligo and other leukodermas. METHODS: A retrospective review of electronic medical records was conducted for all MKTPs performed at Henry Ford Hospital between January 2009 and April 2014. Repigmentation was assessed by a 5-point grading scale (poor to excellent) and Vitiligo Area Scoring Index (VASI)...
May 11, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28499992/segmentation-and-quantification-for-angle-closure-glaucoma-assessment-in-anterior-segment-oct
#17
Huazhu Fu, Yanwu Xu, Stephen Lin, Xiaoqin Zhang, Damon Wing Kee Wong, Jiang Liu, Alejandro Frangi, Mani Baskaran, Tin Aung
Angle-closure glaucoma is a major cause of irreversible visual impairment and can be identified by measuring the anterior chamber angle (ACA) of the eye. The ACA can be viewed clearly through Anterior Segment Optical Coherence Tomography (AS-OCT), but the imaging characteristics and the shapes and locations of major ocular structures can vary significantly among different AS-OCT modalities, thus complicating image analysis. To address this problem, we propose a datadriven approach for automatic AS-OCT structure segmentation, measurement and screening...
May 10, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28498910/extra-anatomical-bypass-in-complex-and-recurrent-aortic-coarctation-and-hypoplastic-arch%C3%A2
#18
Eva Maria Delmo Walter, Mariano Francisco Del Maria Javier, Roland Hetzer
OBJECTIVES: Our goal was to report the selection schemes, technical variations and long-term outcome of extra-anatomical bypass to correct complex, recurrent aortic coarctation and hypoplastic aortic arch. METHODS: Between 1989 and 2012, 53 patients (mean age 13.2 ± 4.3, median 11.6, range 9-23 years) with complex aortic coarctation ( n  = 33; long-segment hypoplastic aortic arch in 15), recurrent coarctation ( n  = 20; anastomosic pseudoaneurysm in 10), underwent correction using extra-anatomical bypass, either with ( n  = 18: femoral bypass = 13, left heart bypass = 5) or without ( n  = 35) extracorporeal circulation via a left lateral thoracotomy ( n = 48) and combined median sternotomy and median laparotomy ( n  = 5)...
May 11, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28498264/defining-the-hook-region-anatomy-of-the-guinea-pig-cochlea-for-modeling-of-inner-ear-surgery
#19
Jonathon Lo, Phillip Sale, Sudanthi Wijewickrema, Luke Campbell, Hayden Eastwood, Stephen John O'leary
HYPOTHESIS: The aim of this study was to describe the hook region anatomy of the guinea pig cochlea to identify the optimal surgical approach for cochlear implantation and to determine what anatomical structures are at risk. BACKGROUND: Animal studies investigating hearing loss after cochlear implantation surgery are currently constrained by the lack of a reproducible implantation model. METHODS: Guinea pig cochleae were imaged using thin-sheet laser imaging microscopy...
May 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28497844/echocardiographic-evaluation-of-right-ventricular-systolic-function-the-traditional-and-innovative-approach
#20
Dorota Smolarek, Marcin Gruchała, Wojciech Sobiczewski
Estimation of right ventricular (RV) performance still remains technically challenging due to its anatomical and functional distinctiveness. The current guidelines for the echocardiographic quantification of RV function recommend using multiple indices to describe the RV in a thorough and comprehensive manner, such as RV index of myocardial performance, tricuspid annular plane systolic excursion, fractional area change, Doppler tissue imaging-derived tricuspid lateral annular systolic velocity (S'-wave), three-dimensional RV ejection fraction (3D RVEF), longitudinal strain (RVLS)/strain rate by speckle-tracking echocardiography (STE)...
May 12, 2017: Cardiology Journal
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