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https://www.readbyqxmd.com/read/28433440/spatial-compounding-technique-to-obtain-rotation-elastogram-a-feasibility-study
#1
AliArshad Kothawala, Sowmiya Chandramoorthi, N Ravi Kiran Reddy, Arun Kumar Thittai
The perception of stiffness and slipperiness of a breast mass on palpation is used by physicians to assess the level of suspicion of a lesion as being malignant or benign. However, most current ultrasound elastography imaging methods provide only stiffness-related information. There is no existing approach that provides information about the local rigid body rotation undergone by only a loosely bonded, asymmetrically oriented lesion subjected to a small quasi-static compression. The inherent poor lateral resolution in ultrasound imaging poses a limitation in estimating the local rigid body rotation...
April 19, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28433436/subharmonic-aided-pressure-estimation-for-monitoring-interstitial-fluid-pressure-in-tumors-calibration-and-treatment-with-paclitaxel-in-breast-cancer-xenografts
#2
Valgerdur G Halldorsdottir, Jaydev K Dave, Andrew Marshall, Anya I Forsberg, Traci B Fox, John R Eisenbrey, Priscilla Machado, Ji-Bin Liu, Daniel A Merton, Flemming Forsberg
Interstitial fluid pressure (IFP) in rats with breast cancer xenografts was non-invasively estimated using subharmonic-aided pressure estimation (SHAPE) versus an invasive pressure monitor. Moreover, monitoring of IFP changes after chemotherapy was assessed. Eighty-nine rats (calibration n = 25, treatment n = 64) were injected with 5 × 10(6) breast cancer cells (MDA-MB-231). Radiofrequency signals were acquired (39 rats successfully imaged) with a Sonix RP scanner (BK Ultrasound, Richmond, BC, Canada) using a linear array (L9-4, transmit/receive: 8/4 MHz) after administration of Definity (Lantheus Medical Imaging, North Billerica, MA, USA; 180 μL/kg) and compared with readings from an invasive pressure monitor (Stryker, Berkshire, UK)...
April 19, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28428649/role-of-magnetic-resonance-imaging-in-the-planning-of-breast-cancer-treatment-strategies-comparison-with-conventional-imaging-techniques
#3
Luciana Karla Lira França, Almir Galvão Vieira Bitencourt, Hugo Lamartine Souza Paiva, Caroline Baptista Silva, Nara Pacheco Pereira, Jociana Paludo, Luciana Graziano, Camila Souza Guatelli, Juliana Alves de Souza, Elvira Ferreira Marques
OBJECTIVE: To assess the role of magnetic resonance imaging (MRI) in the planning of breast cancer treatment strategies. MATERIALS AND METHODS: The study included 160 women diagnosed with breast cancer, who underwent breast MRI for preoperative staging. Using Pearson's correlation coefficient (r), we compared the size of the primary tumor, as determined by MRI, by conventional imaging (mammography and ultrasound), and in the pathological examination (gold standard)...
March 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28427743/microbubble-detection-and-ultrasound-guided-vacuum-assisted-biopsy-of-axillary-lymph-nodes-in-patients-with-breast-cancer
#4
P Britton, P Willsher, K Taylor, F Kilburn-Toppin, E Provenzano, P Forouhi, J Benson, A Agrawal, J R Forman, M G Wallis
AIMS: To assess the feasibility of undertaking microbubble-guided vacuum-assisted biopsy (VAB) of the sentinel lymph node (SLN) and determine its sensitivity in detecting metastases. Patient experience and the impact of VAB on subsequent axillary surgery were also evaluated. MATERIALS AND METHODS: Patients with a normal axillary ultrasound or benign core biopsy planned for surgical SLN biopsy were recruited. Part 1 of the study was used to establish the technique of ultrasound microbubble contrast to detect the SLN...
April 17, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28427629/development-of-a-novel-folate-modified-nanobubbles-with-improved-targeting-ability-to-tumor-cells
#5
Sujuan Duan, Lu Guo, Dandan Shi, Mengmeng Shang, Dong Meng, Jie Li
Conjugation of folate (FOL) to nanobubbles could enhance the selective targeting to tumors expressing high levels of folate receptor (FR). To further improve the selective targeting ability of FOL-modified nanobubbles, a novel FOL-targeted nanobubble ((FOL)2-NB) with increasing FOL content (accomplished by linking two FOL molecules per DSPE-PEG2000 chain) was synthesized, through the methods of mechanical shaking and low-speed centrifugation based on lipid-stabilized perfluoropropane. The bubble size and distribution range were measured by dynamic light scattering (DLS)...
July 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28412952/rayleigh-maximum-likelihood-bilateral-filter-for-ultrasound-image-enhancement
#6
Haiyan Li, Jun Wu, Aimin Miao, Pengfei Yu, Jianhua Chen, Yufeng Zhang
BACKGROUND: Ultrasound imaging plays an important role in computer diagnosis since it is non-invasive and cost-effective. However, ultrasound images are inevitably contaminated by noise and speckle during acquisition. Noise and speckle directly impact the physician to interpret the images and decrease the accuracy in clinical diagnosis. Denoising method is an important component to enhance the quality of ultrasound images; however, several limitations discourage the results because current denoising methods can remove noise while ignoring the statistical characteristics of speckle and thus undermining the effectiveness of despeckling, or vice versa...
April 17, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28412736/tumor-biology-clinicopathological-characteristics-and-prognosis-of-screen-detected-t1-invasive-non-palpable-breast-cancer-in-asymptomatic-chinese-women-2001-2014
#7
Bo Pan, Ru Yao, Yi-Dong Zhou, Qing-Li Zhu, Jie Shi, Qian-Qian Xu, Chang-Jun Wang, Shan-Shan You, Feng Mao, Yan Lin, Song-Jie Shen, Zhi-Yong Liang, Yu-Xin Jiang, Qiang Sun
BACKGROUND: Mammography screening usually detects low-risk breast cancer in the western world. However, little is known about the ultrasound and mammography screen-detected T1 invasive non-palpable breast cancer (NPBC) in asymptomatic Chinese women. RESULTS: With the increase of tumor size (T1a, b, c), lymph node positivity (8.7%, 18.3%, 26.0%, p = 0.018), pN (p = 0.028) and TNM stage (p = 0.035) increased accordingly. Tumor size (T1a, b, c) was correlated with high Ki-67 index (defined as ≥ 14%, 37...
February 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/28411680/mr-imaging-future-imaging-techniques
#8
REVIEW
Lilian C Wang
Breast MR imaging is the most sensitive modality for breast cancer detection. This high sensitivity has led to widespread adoption of this technique, particularly in screening women at elevated risk for breast cancer. Despite its high sensitivity, standard breast MR imaging protocols are limited by moderate specificity and relative higher cost, longer examination time, longer interpretation time, and lower availability compared with mammography and ultrasound. As such, new techniques in MR imaging, including abbreviated breast MR imaging, pharmacokinetic modeling, and diffusion-weighted imaging, are active areas of research...
May 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/28411677/breast-density-legislation-and-clinical-evidence
#9
REVIEW
Regina J Hooley
Breast density inform legislation is widely accepted in the United States and has fueled research regarding the clinical significance of dense breast tissue present on mammography and the value of supplemental screening. This article reviews the origins and current status of breast density inform laws and strategies for optimal breast density determination. Clinical evidence that dense breast tissue is associated with increased breast cancer risk is presented, together with a review of relative risk compared with other risk factors...
May 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/28410763/correlation-between-upper-limb-volume-and-arterial-and-venous-blood-flow-velocity-in-lymphedema-secondary-to-breast-cancer-treatment
#10
Monique Silva Rezende, Ana Luiza Marsengo, Amanda Apolinário, Vânia Tie Koga Ferreira, Elaine Caldeira de Oliveira Guirro
OBJECTIVE: The purpose of this study was to correlate upper limb volume and arterial and venous blood flow velocity in breast cancer survivors. METHODS: A cross-sectional study was conducted on 30 women with lymphedema and a mean age of 55.60 years (standard deviation = 8.12). For the assessment of upper limb volume, perimetry was performed with measures at 6 points on the limb, which were mathematically calculated as volume. The blood flow velocity of the axillary and brachial arteries and veins were assessed by Doppler ultrasound with a probe at 4 MHz...
April 12, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28409843/reproducibility-of-quantitative-high-throughput-bi-rads-features-extracted-from-ultrasound-images-of-breast-cancer
#11
Yuzhou Hu, Mengyun Qiao, Yi Guo, Yuanyuan Wang, Jinhua Yu, Jiawei Li, Cai Chang
PURPOSE: Digital Breast Imaging Reporting and Data System (BI-RADS) features extracted from ultrasound images are essential in computer-aided diagnosis, prediction, and prognosis of breast cancer. This study focuses on the reproducibility of quantitative high-throughput BI-RADS features in the presence of variations due to different segmentation results, various ultrasound machine models, and multiple ultrasound machine settings. METHODS: Data set 1 consists of 399 patients with invasive breast cancer and is used as the training set to measure the reproducibility of features, while data set 2 consists of 138 other patients and is a validation set used to evaluate the diagnosis performances of the final reproducible features...
April 13, 2017: Medical Physics
https://www.readbyqxmd.com/read/28409837/clinical-accuracy-of-preoperative-breast-mri-for-breast-cancer
#12
Jennifer Tseng, Alexandra Kyrillos, Erik Liederbach, Georgia G Spear, Jacob Ecanow, Chi-Hsiung Wang, Tom Czechura, Olga Kantor, Megan Miller, David J Winchester, Catherine E Pesce, Sarah Rabbitt, Katharine Yao
BACKGROUND: It is unclear if breast magnetic resonance imaging (MRI) is more accurate than mammography (MGM) and ultrasound (U/S) in aggregate for patients with invasive cancer. METHODS: We compared concordance of combined tumor size and tumor foci between MRI and MGM and U/S combined to pathological tumor size and foci as the gold standard from 2009 to 2015. Tumor size was nonconcordant if it differed from the pathologic size by ≥33% and tumor foci was nonconcordant if >1 foci were seen...
April 13, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28409065/malignant-clear-cell-hidradenoma-of-the-breast
#13
Isaac Chambers, Ahmad K Rahal, Pavan S Reddy, K James Kallail
A 58-year-old female had a mass in the right breast palpable beneath the areola. A mammogram revealed a 1.5-centimeter soft tissue density that was confirmed with a subsequent ultrasound. The patient underwent a core needle biopsy which was initially reported as a moderately differentiated invasive ductal carcinoma. Immunohistochemical analysis revealed negative staining for estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor (HER2), mammaglobin, and gross cystic disease fluid protein 15 (GCDFP-15)...
March 1, 2017: Curēus
https://www.readbyqxmd.com/read/28403815/gamma-probe-and-ultrasound-guided-fine-needle-aspiration-cytology-of-the-sentinel-node-gulf-trial-overview-of-the-literature-pilot-and-study-protocol
#14
Charlotte M C Oude Ophuis, Lisa Linetta B Koppert, Cécile de Monyé, Carolien H M van Deurzen, Senada Koljenović, Alexander C J van Akkooi, Cornelis Kees Verhoef, Dirk J Grünhagen
BACKGROUND: Sentinel node (SN) biopsy (SNB) detects clinically occult metastases of breast cancer and melanoma in 20-30%. Wound infections, seroma and lymph edema occur in up to 10%. Targeted ultrasound (US) of the SN, (with fine needle aspiration cytology (FNAC) if appropriate) has been investigated as a minimally invasive alternative, but reported sensitivity rates are too low to replace SNB. Our hypothesis is that the use of a handheld gamma probe concomitant with US may improve sensitivity...
April 12, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28401902/a-priori-prediction-of-neoadjuvant-chemotherapy-response-and-survival-in-breast-cancer-patients-using-quantitative-ultrasound
#15
Hadi Tadayyon, Lakshmanan Sannachi, Mehrdad J Gangeh, Christina Kim, Sonal Ghandi, Maureen Trudeau, Kathleen Pritchard, William T Tran, Elzbieta Slodkowska, Ali Sadeghi-Naini, Gregory J Czarnota
Quantitative ultrasound (QUS) can probe tissue structure and analyze tumour characteristics. Using a 6-MHz ultrasound system, radiofrequency data were acquired from 56 locally advanced breast cancer patients prior to their neoadjuvant chemotherapy (NAC) and QUS texture features were computed from regions of interest in tumour cores and their margins as potential predictive and prognostic indicators. Breast tumour molecular features were also collected and used for analysis. A multiparametric QUS model was constructed, which demonstrated a response prediction accuracy of 88% and ability to predict patient 5-year survival rates (p = 0...
April 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28401771/preoperative-magnetic-resonance-imaging-in-patients-with-stage-i-invasive-ductal-breast-cancer-a-prospective-randomized-study
#16
N Brück, I Koskivuo, P Boström, J Saunavaara, R Aaltonen, R Parkkola
BACKGROUND AND AIMS: Preoperative magnetic resonance imaging has become an important complementary imaging technique in patients with breast cancer, providing additional information for preoperative local staging. Magnetic resonance imaging is recommended selectively in lobular breast cancer and in patients with dense breast tissue in the case when mammography and ultrasound fail to fully evaluate the lesion, but the routine use of magnetic resonance imaging in all patients with invasive ductal carcinoma is controversial...
April 1, 2017: Scandinavian Journal of Surgery: SJS
https://www.readbyqxmd.com/read/28397344/a-comparison-of-the-diagnostic-accuracy-of-magnetic-resonance-imaging-to-axillary-ultrasound-in-the-detection-of-axillary-nodal-metastases-in-newly-diagnosed-breast-cancer
#17
Matthew A Assing, Bhavika K Patel, Neel Karamsadkar, Jared Weinfurtner, Omar Usmani, John V Kiluk, Jennifer S Drukteinis
Patients with a diagnosis of invasive breast cancer are increasingly undergoing breast magnetic resonance imaging (MRI) for preoperative staging including evaluation of axillary lymph node metastases (ALNM). This retrospective study aims to evaluate the utility of adding axillary ultrasound (AUS) in the preoperative setting when an MRI is planned or has already been performed. This IRB approved, HIPAA compliant study reviewed a total of 271 patients with a new diagnosis of invasive breast cancer at a single institution, between June 1, 2010 and June 30, 2013...
April 10, 2017: Breast Journal
https://www.readbyqxmd.com/read/28395985/manual-lymphatic-drainage-in-blood-circulation-of-upper-limb-with-lymphedema-after-breast-cancer-surgery
#18
Raquel Michelini Guerero, Lais Mara Siqueira das Neves, Rinaldo Roberto de Jesus Guirro, Elaine Caldeira de Oliveira Guirro
OBJECTIVE: The purpose of this study was to assess blood flow after manual lymphatic drainage (MLD) in women who had received surgery for breast cancer and had post-axillary lymphadenectomy lymphedema. METHODS: Sixteen volunteers (mean age 64 ± 11.44 years) were divided into 2 groups. Those in group 1 received MLD without upper limb elevation, and those in group 2 received MLD with elevation of 30° of the upper limb. Blood flow velocity of the brachial vein and artery were measured using Doppler ultrasound before, immediately after, and 30 minutes after MLD, with and without 30° of upper limb elevation as defined by a random crossover design and an interval (washout) of 7 days...
April 8, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28390169/enhancing-your-acoustics-ultrasound-image-optimization-of-breast-lesions
#19
Bianca Carpentier, Jessica Hayward, Lori Strachowski
A general understanding of ultrasound physics relative to image optimization is essential when performing breast ultrasound examinations and in accurately interpreting images of the breast. Appropriate technique is crucial to achieve accurate lesion characterization and is emphasized in the second edition of the American College of Radiology Breast Imaging Reporting and Data System for ultrasound (2013). This pictorial essay reviews clinically relevant ultrasound physics to best characterize breast lesions for guiding the clinician to the proper diagnosis...
April 8, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28389229/ultrasound-features-of-retroareolar-breast-carcinoma
#20
R Ferre, M Pare, B Mesurolle
PURPOSE: The goal of this study was to report the ultrasound features of retroareolar breast carcinoma (RABC). MATERIALS AND METHODS: The ultrasound examinations of the breast of 53 women with RABC were reviewed. They had a mean age of 67.2 years±13.4 (standard deviation [SD]) (range: 46-85 years). RABC were defined as carcinomas located less than 2cm from the nipple on mammogram. RESULTS: Among the 53 RABC, 42 (42/53; 79%) were invasive ductal carcinomas, 6 (6/53; 11%) were invasive lobular carcinomas, 4 (4/53; 8%) were ductal carcinomas in situ and 1 (1/53; 2%) was intracystic papillary carcinoma...
April 4, 2017: Diagnostic and Interventional Imaging
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