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Breast ultrasound

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https://www.readbyqxmd.com/read/29792747/interpretation-time-using-a-concurrent-read-computer-aided-detection-system-for-automated-breast-ultrasound-in-breast-cancer-screening-of-women-with-dense-breast-tissue
#1
Yulei Jiang, Marc F Inciardi, Alexandra V Edwards, John Papaioannou
OBJECTIVE: The purpose of this study was to compare diagnostic accuracy and interpretation time of screening automated breast ultrasound (ABUS) for women with dense breast tissue without and with use of a recently U.S. Food and Drug Administration-approved computer-aided detection (CAD) system for concurrent read. MATERIALS AND METHODS: In a retrospective observer performance study, 18 radiologists interpreted a cancer-enriched set (i.e., cancer prevalence higher than in the original screening cohort) of 185 screening ABUS studies (52 with and 133 without breast cancer)...
May 24, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29791029/development-of-a-3d-ultrasound-guidance-system-for-permanent-breast-seed-implantation
#2
Justin Michael, Daniel Morton, Deidre Batchelar, Michelle Hilts, Juanita Crook, Aaron Fenster
PURPOSE: Permanent breast seed implantation (PBSI) is a promising radiotherapy technique for early-stage breast cancer, completed in a single visit by permanently implanting 103 Pd seeds using needles inserted through a template and guided by 2D ultrasound (US). However, operator dependence has been highlighted as a limitation of this procedure. Consequently, we propose and have developed an intraoperative guidance system using 3D US and an instrumented mechanical arm to provide intraoperative 3D imaging and needle template tracking...
May 23, 2018: Medical Physics
https://www.readbyqxmd.com/read/29790803/ultrasound-guided-delivery-of-thymidine-kinase-nitroreductase-dual-therapeutic-genes-by-pegylated-plga-pie-nanoparticles-for-enhanced-triple-negative-breast-cancer-therapy
#3
Rammohan Devulapally, Taehwa Lee, Aarohi Barghava-Shah, Thillai V Sekar, Kira Foygel, Sunitha V Bachawal, Jürgen K Willmann, Ramasamy Paulmurugan
AIM: Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype. Since no targeted therapy is available, gene-directed enzyme prodrug therapy (GDEPT) could be an attractive strategy for treating TNBC. MATERIALS & METHODS:  Polyethylene glycol (PEG)ylated-poly(lactic-co-glycolic acid)/polyethyleneimine nanoparticles (PLGA/PEI NPs) were synthesized and complexed with TK-NTR fusion gene. Ultrasound (US) and microbubble (MB) mediated sonoporation was used for efficient delivery of the TK-NTR-DNA-NP complex to TNBC tumor in vivo for cancer therapy...
May 2018: Nanomedicine
https://www.readbyqxmd.com/read/29789777/a-normalized-shear-deformation-indicator-for-ultrasound-strain-elastography-in-breast-tissues-an-in-vivo-feasibility-study
#4
Jingfeng Jiang, Bo Peng
The shear deformation under loads contains useful information for distinguishing benign breast lesions from malignant ones. In this study, we proposed a normalized shear deformation indicator (NSDI) that was derived from the concept of principal strains. Since the NSDI requires both high-quality axial and lateral (parallel and perpendicular to the beam, resp.) displacement estimates, a strategy combining high-quality speckle tracking with signal "denoising" was employed. Both techniques were previously published by our group...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29789520/t1-weighted-dynamic-contrast-enhanced-magnetic-resonance-imaging-dce-mri-to-distinguish-between-concurrent-cholesterol-granuloma-and-invasive-ductal-carcinoma-of-the-breast-a-case-report
#5
Cheng-Chuan Hu, Tsun-Hou Chang, Hsian-He Hsu, Yi-Jen Pen, Jyh-Cherng Yu
BACKGROUND Cholesterol granuloma is a benign condition that can be misdiagnosed as breast cancer on mammographic and ultrasound imaging. A case of concomitant cholesterol granuloma with invasive ductal carcinoma of the left breast was imaged with ultrasound elastography and magnetic resonance imaging (MRI) methods, including T1-weighted dynamic contrast-enhanced MRI (DCE-MRI), before biopsy and histopathology. CASE REPORT A 52-year-old woman, with a previous history of intraduct papillomas in both breasts, underwent six-monthly follow-up breast imaging...
May 23, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29788010/metaplastic-breast-cancer-masquerading-as-liposarcoma-of-the-breast-a-case-report-following-oncoplastic-treatment
#6
Maiar Elghobashy, Naren Basu, Robert Warner, John Dickson, Abeer M Shaaban
Mammary liposarcoma is among the rarest of breast tumours. Here we report the presentation, macroscopic, microscopic, and immunohistochemical features of an extremely rare case of metaplastic carcinoma with extensive pleomorphic liposarcomatous differentiation. A 47-year-old woman presented with bilateral grade III breast ptosis and a 3 × 4 cm mass in the lower outer quadrant of the left breast. Mammography and ultrasound confirmed a well-defined mass. A core biopsy performed was diagnosed as pleomorphic liposarcoma...
May 22, 2018: Pathobiology: Journal of Immunopathology, Molecular and Cellular Biology
https://www.readbyqxmd.com/read/29787513/real-time-ultrasound-assisted-gluteal-fat-grafting
#7
Alvaro Luiz Cansancao, Alexandra Condé-Green, Rafael A Vidigal, Ricardo Luis Rodriguez, Richard A D'Amico
BACKGROUND: Outcomes in primary breast augmentation depend on careful preoperative planning and clear communication between patient and surgeon. Three-dimensional imaging with computer simulation is an evolving technology with the potential to enhance the preoperative consultation for patients considering primary breast augmentation. The purpose of this study was to prospectively evaluate the impact of three-dimensional imaging with computer simulation on patient-reported and objective, mammometric outcomes in women undergoing primary breast augmentation...
May 16, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29785158/obtaining-adequate-surgical-margin-status-in-breast-conservation-therapy-intraoperative-ultrasound-guided-resection-versus-specimen-mammography
#8
Maria Mihaela Pop, Silviu Cristian, Orsolya Hanko-Bauer, Dana Valentina Ghiga, Rares Georgescu
Background and aim: The purpose of breast-conserving surgery (BCS) for women with cancer is to perform an oncological radical procedure with disease-free margins at the final histological assessment and with the best aesthetic result possible. Intraoperative resected specimen ultrasound and intraoperative resected specimen mammography may reduce the rates of positive margins and reexcision among patients undergoing conserving therapy. Our objective is to compare the two methods with the histopathological results for a preset cut off and asses which parameters can influence the positive margin status...
2018: Clujul Medical (1957)
https://www.readbyqxmd.com/read/29784436/a-3-d-region-growing-motion-tracking-method-for-ultrasound-elasticity-imaging
#9
Yuqi Wang, Jingfeng Jiang, Timothy J Hall
A 3-D region-growing motion-tracking (RGMT) method for ultrasound elasticity imaging is described. This 3-D RGMT method first estimates the displacements at a sparse subset of points, called seeds; uses an objective measure to determine, among those seeds, which displacement estimates to trust; and then performs RGMT in three dimensions to estimate displacements for the remaining points in the field. During the growing process in three dimensions, the displacement estimate at one grid point is employed to guide the displacement estimation of its neighboring points using a 3-D small search region...
May 18, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29781232/predictors-of-outcomes-in-managing-breast-abscesses-a-large-retrospective-single-center-analysis
#10
Miriam David, Priyanka Handa, Maria Castaldi
We have retrospectively examined a wide range of clinical characteristics, sonographic features, microbiology, and antibiotic regimens in patients with breast abscesses to seek predictive features related to outcome. Because consensus for optimal treatment of breast abscesses has moved toward minimally invasive management using single or repeated needle aspiration (ASP) coupled with adjuvant antibiotics, we assessed whether any factors correlate with the need for repeat procedures by analyzing the number of ASPs and/or surgical incision and drainage (I&D) per abscess...
May 20, 2018: Breast Journal
https://www.readbyqxmd.com/read/29772934/image-guided-vacuum-assisted-breast-biopsy-in-the-diagnosis-of-breast-microcalcifications
#11
Jun Liu, Linping Huang
Objective The present study was performed to assess the accuracy and clinical value of image-guided vacuum-assisted breast biopsy in the diagnosis of mammography-detected breast microcalcifications. Methods This prospective study involved 100 patients with suspicious mammography-detected microcalcifications who underwent image-guided vacuum-assisted breast biopsies from January 2013 to October 2016. Stereotactic vacuum-assisted breast biopsy (SVAB) was performed in 64 patients, and ultrasound (US)-guided vacuum-assisted breast biopsy (US-VAB) was performed in 36 patients in whom application of SVAB was difficult...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29770535/ultrasound-guided-transversus-thoracic-plane-block-parasternal-block-and-fascial-planes-hydrodissection-for-internal-mammary-post-thoracotomy-pain-syndrome
#12
Emanuele Piraccini, Giulia Biondi, Helen Byrne, Morena Calli, Daniele Bellantonio, Giovanni Musetti, Stefano Maitan
INTRODUCTION: Pectoral Nerves Block (PECS) and Serratus Plane Block (SPB) have been used to treat persistent post-surgical pain after breast and thoracic surgery, however they cannot block the internal mammary region, so a residual pain may occur in that region. Parasternal block (PSB) and Thoracic Transversus Plane Block (TTP) anesthetize the anterior branches of T2-6 intercostal nerves thus they can provide analgesia to the internal mammary region. METHODS: We describe a 60-year-old man suffering from right post thoracotomy pain syndrome with residual pain located in the internal mammary region after a successful treatment with PECS and SPB We performed a PSB and TTP and hydrodissection of fascial planes with triamcinolone and Ropivacaine...
May 16, 2018: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29770313/management-of-the-axilla-in-metaplastic-breast-carcinoma
#13
Brittany L Murphy, Robert T Fazzio, Tanya L Hoskin, Katrina N Glazebrook, Michael G Keeney, Elizabeth B Habermann, Tina J Hieken
Background: Metaplastic breast cancer (MBC), characterized by admixed epithelial, squamous or mesenchymal elements, constitutes <1% of breast cancers and has a poor prognosis but a paradoxically low reported rate of axillary lymph node (LN) involvement. Due to its rarity, data on appropriate axillary management is lacking, prompting this investigation of LN status and outcomes. Methods: We identified 41 MBC patients treated at our institution 2001-2011 who were followed for a median of 66 months...
April 2018: Gland Surgery
https://www.readbyqxmd.com/read/29770285/large-non-enhancing-breast-cancer-on-breast-magnetic-resonance-imaging-a-case-report
#14
Johannes Peters, Wei Che Tsai, Gudrun Peters
A 55-year-old female presented with vague symptoms in the lateral left breast. Digital breast tomosynthesis and breast ultrasound showed no focal lesion, and magnetic resonance imaging (MRI) was subsequently performed. No suspicious enhancement was seen on MRI; in particular, no suspicious lesion was seen in the area of clinical concern. In view of persisting focal mastalgia and vague parenchymal changes in the symptomatic area on repeat targeted ultrasound, a core biopsy was performed. Final pathology after left mastectomy with axillary clearance showed a 42 mm grade 2 invasive ductal carcinoma...
March 15, 2018: Curēus
https://www.readbyqxmd.com/read/29768415/automated-and-real-time-segmentation-of-suspicious-breast-masses-using-convolutional-neural-network
#15
Viksit Kumar, Jeremy M Webb, Adriana Gregory, Max Denis, Duane D Meixner, Mahdi Bayat, Dana H Whaley, Mostafa Fatemi, Azra Alizad
In this work, a computer-aided tool for detection was developed to segment breast masses from clinical ultrasound (US) scans. The underlying Multi U-net algorithm is based on convolutional neural networks. Under the Mayo Clinic Institutional Review Board protocol, a prospective study of the automatic segmentation of suspicious breast masses was performed. The cohort consisted of 258 female patients who were clinically identified with suspicious breast masses and underwent clinical US scan and breast biopsy...
2018: PloS One
https://www.readbyqxmd.com/read/29766686/multimodal-approach-in-assessment-of-the-response-of-breast-cancer-to-neoadjuvant-chemotherapy
#16
Mikhail Viktorovich Pavlov, Tatyana Igorevna Kalganova, Yekaterina Sergeevna Lyubimtseva, Vladimir Ivanovich Plekhanov, German Yurievich Golubyatnikov, Olga Yevgenyevna Ilyinskaya, Anna Gennadjevna Orlova, Pavel Vladimirovich Subochev, Dmitriy Vladimirovich Safonov, Natalia Mikhailovna Shakhova, Anna Vladimirovna Maslennikova
The ability for noninvasive visualization of functional changes of a tumor's oxygenation and circulatory system offers new advantages for prognosis and monitoring of the treatment efficacy. The results of breast cancer oxygen state study under chemotherapy action obtained by diffuse optical spectroscopy (DOS) in combination with Doppler ultrasonic imaging are presented. Complex use of optical and ultrasound methods gives complementary information about the size of the tumor node, peculiarities of its vascular bed, rate of its blood flow as well as oxygenation, and provide a picture of the tumor response to treatment...
May 2018: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/29764474/acute-blindness-as-a-presenting-sign-of-childhood-endemic-burkitt-s-lymphoma-in-cameroon-a-case-report
#17
Brice N Vofo, Gaelle V F Ngankam, Calypse A Ngwasiri, Jeannine A Atem, Leopold N Aminde
BACKGROUND: Endemic Burkitt's lymphoma is found predominantly in malaria holoendemic zones, typically in the tropical rain forest of Africa. It usually presents as an extra-nodal tumour in children and young adults with predilection for jaws and soft tissues of the abdomen. Clinical features depend on the primary tumour site, extent of the disease and histologic subtype. Acute blindness as a presentation sign is rare. CASE PRESENTATION: A 13 year old African female presented to our facility with a 3 week history of painful abdominal distention, and loss of vision of the left eye...
May 16, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29763773/ultrasound-doppler-as-an-imaging-modality-for-selection-of-murine-4t1-breast-tumors-for-combination-radiofrequency-hyperthermia-and-chemotherapy
#18
Martyna Krzykawska-Serda, Jason Chak-Shing Ho, Matthew J Ware, Justin J Law, Jared M Newton, Lam Nguyen, Mahdi Agha, Steven A Curley, Stuart J Corr
Noninvasive radiofrequency-induced (RF) hyperthermia has been shown to increase the perfusion of chemotherapeutics and nanomaterials through cancer tissue in ectopic and orthotopic murine tumor models. Additionally, mild hyperthermia (37°C-45°C) has previously shown a synergistic anticancer effect when used with standard-of-care chemotherapeutics such as gemcitabine and Abraxane. However, RF hyperthermia treatment schedules remain unoptimized, and the mechanisms of action of hyperthermia and how they change when treating various tumor phenotypes are poorly understood...
May 11, 2018: Translational Oncology
https://www.readbyqxmd.com/read/29758547/ultrasound-assisted-gene-and-photodynamic-synergistic-therapy-with-multifunctional-foxa1-sirna-loaded-porphyrin-microbubbles-for-enhancing-therapeutic-efficacy-for-breast-cancer
#19
Ranran Zhao, Xiaolong Liang, Bo Zhao, Min Chen, Renfa Liu, Sujuan Sun, Xiuli Yue, Shumin Wang
To improve the non-invasive therapeutic efficacy for ER positive breast cancer (ER+ BC), we fabricated a multifunctional FOXA1 loaded porphyrin microbubble to combine photodynamic therapy (PDT) and gene therapy of FOXA1 knockdown (KD) with ultrasound targeted microbubble destruction (UTMD) technology under the guidance of contrast enhanced ultrasound (CEUS). Cationic porphyrin microbubbles (CpMBs) were firstly fabricated from a porphyrin grafted lipid with two cationic amino groups (PGL-NH2) and fluorocarbon inert gas of C3 F8 ...
May 3, 2018: Biomaterials
https://www.readbyqxmd.com/read/29755937/rapid-scanning-wide-field-clutter-elimination-in-epi-optoacoustic-imaging-using-comb-lovit
#20
Tigran Petrosyan, Maria Theodorou, Jeff Bamber, Martin Frenz, Michael Jaeger
Epi-style optoacoustic (OA) imaging provides flexibility by integrating the irradiation optics and ultrasound receiver, yet clutter generated by optical absorption near the probe obscures deep OA sources. Localised vibration tagging (LOVIT) retrieves OA signal from images that are acquired with and without a preceding ultrasonic pushing beam: Radiation force leads to a phase shift of signals coming from the focal area resulting in their visibility in a difference image, whereas clutter from outside the pushing beam is eliminated...
June 2018: Photoacoustics
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