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https://www.readbyqxmd.com/read/28717615/outcomes-of-prolotherapy-for-intra-tendinous-achilles-tears-a-case-series
#1
Otto Chan, Ben Havard, Sarah Morton, Mel Pritchard, Nicola Maffulli, Tom Crisp, Nat Padhiar, Jeremy David Perry, John King, Dylan Morrissey
BACKGROUND: The intra-tendinous tear is a new pathology that is defined as a discontinuity of fibres situated entirely within the tendon. Prolotherapy involves injecting an irritant, such as hyperosmolar dextrose, to stimulate a tissue healing response and ultimately reduce pain. METHODS: 43 consecutive patients diagnosed with an intra-tendinous tear were included (27 males: 16 females, mean (SD) age 41 (11.3). Patients were injected with 0.4ml-1.5ml (mean 0.8ml) of 50% dextrose and 0...
January 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28717612/intratendinous-tears-of-the-achilles-tendon-a-new-pathology-analysis-of-a-large-4-year-cohort
#2
Otto Chan, Sarah Morton, Mel Pritchard, Tina Parkes, Peter Malliaras, Tom Crisp, Nat Padhiar, Nicola Maffulli, John King, Dylan Morrissey
BACKGROUND: Achillodynia is common and includes Achilles tendinopathy, partial Achilles tears and Achilles tendon ruptures. However, we believe an additional pathology should be considered for Achillodynia differentials - the intratendinous tear (ITT). METHODS: Examinations of 740 achillodynic patients in one specialist centre were reviewed. ITTs were defined as a clearly visualised echopoor area situated centrally and extending to, but not through the tendon periphery, with pain on palpation and no clinical findings consistent with Achilles rupture...
January 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28705956/rapid-recovery-gene-downregulation-during-excess-light-stress-and-recovery-in-arabidopsis
#3
Peter Alexander Crisp, Diep Ganguly, Aaron B Smith, Kevin D Murray, Gonzalo M Estavillo, Iain R Searle, Ethan Ford, Ozren Bogdanović, Ryan Lister, Justin O Borevitz, Steven R Eichten, Barry J Pogson
Stress recovery may prove to be a promising approach to increase plant performance, and theoretically, mRNA instability may facilitate faster recovery. Transcriptome (RNA-seq, qPCR, sRNA-seq, PARE) and methylome profiling during repeated excess-light stress and recovery was performed at intervals as short as three minutes. We demonstrate that 87% of the stress-upregulated mRNAs analysed exhibit very rapid recovery. For instance, HSP101 abundance declined two-fold every 5.1 minutes. We term this phenomenon Rapid Recovery Gene Downregulation (RRGD), whereby mRNA abundance rapidly decreases promoting transcriptome resetting...
July 13, 2017: Plant Cell
https://www.readbyqxmd.com/read/28694151/liposomal-bupivacaine-decreases-pain-following-retropubic-sling-placement-a-randomized-placebo-controlled-trial
#4
Donna Mazloomdoost, Rachel N Pauls, Erin N Hennen, Jennifer Y Yeung, Benjamin C Smith, Steven D Kleeman, Catrina C Crisp
BACKGROUND: Midurethral slings are commonly used to treat stress urinary incontinence. Pain control, however, may be a concern. Liposomal bupivacaine is a local anesthetic with slow release over 72 hours, demonstrated to lower pain scores and decrease narcotic use postoperatively. OBJECTIVES: The objectives were to examine the impact of liposomal bupivacaine on pain scores and narcotic consumption following retropubic midurethral sling placement. STUDY DESIGN: This randomized, placebo-controlled trial enrolled women undergoing retropubic midurethral slings with or without concomitant anterior or urethrocele repair...
July 7, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28689457/survey-on-acrylamide-in-roasted-coffee-and-barley-and-in-potato-crisps-sold-in-italy-by-a-lc-ms-ms-method
#5
Terenzio Bertuzzi, Silvia Rastelli, Annalisa Mulazzi, Amedeo Pietri
A survey on the occurrence of acrylamide (AA) in roasted coffee, barley and potato crisps was carried out using an intra-lab validated LC-MS/MS method. Over the years 2015-2016, 66 samples of coffee, 22 of roasted barley and 22 of potato crisps were collected from retail outlets in Italy. AA was detected in almost all samples. In roasted coffee, the level exceeded 450 µg kg(-1), the limit recommended by the European Commission (EC), in 36.4% of the samples. In roasted barley, mean contamination was slightly lower than in coffee and no sample exceeded the EC limit of 2000 µg kg(-1)...
July 10, 2017: Food Additives & Contaminants. Part B, Surveillance
https://www.readbyqxmd.com/read/28688916/venom-proteome-of-the-yellow-lipped-sea-krait-laticauda-colubrina-from-bali-insights-into-subvenomic-diversity-venom-antigenicity-and-cross-neutralization-by-antivenom
#6
Choo Hock Tan, Kin Ying Wong, Kae Yi Tan, Nget Hong Tan
The venom proteome of Laticauda colubrina (Bali, Indonesia) was elucidated by nano-ESI-LCMS/MS of the venom reverse-phase HPLC fractions. Altogether 31 distinct forms of proteins were identified and clustered into three toxin families: three-finger toxin (3FTX, 66.12% of total venom proteins), phospholipase A2 (PLA2, 33.26%) and cysteine-rich secretory protein (CRiSP, 0.05%). The 3FTX were α-neurotoxins (five long neurotoxins, LNTX, 48.87%; two short neurotoxins, SNTX, 16.70%) and a trace amount of two cytotoxins (CTX, 0...
July 5, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28688515/the-triple-impact-of-nursing
#7
EDITORIAL
Lord Crisp, Mary Watkins
No abstract text is available yet for this article.
May 11, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28671034/acrylamide-in-commercial-foods-and-intake-by-infants-in-estonia
#8
Andres Elias, Mati Roasto, Mari Reinik, Keiu Nelis, Eha Nurk, Terje Elias
Acrylamide is formed when certain foods with low moisture are prepared at above 120 ºC, especially those foods containing asparagine and reducing sugars such as glucose and fructose. Acrylamide is a probable carcinogen, and from animal evidence the margins of exposure indicate a concern for neoplastic effects. On a body weight basis infants´ acrylamide intakes are often higher than those of adults. The aim of the study was to determine acrylamide levels in different commercially-available foods and to assess dietary acrylamide intakes by infants...
July 10, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/28657993/outcomes-and-characteristics-of-patients-undergoing-surgical-management-for-mesh-related-complications
#9
Donna Mazloomdoost, Rachel N Pauls, Steven D Kleeman, Catrina C Crisp
OBJECTIVE: The aims of this study were to describe the characteristics of women presenting with mesh-related complications and evaluate postoperative quality of life, sexual functioning, and patient-perceived outcomes. METHODS: This institutional review board-approved study included a retrospective chart review and a cross-sectional follow-up with validated questionnaires. Demographics and medical histories were collected from charts of women treated for mesh-related complaints between 2010 and 2014...
June 27, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28657649/application-of-pretreatment-methods-on-agricultural-products-prior-to-frying-a-review
#10
REVIEW
Ayobami Olayemi Oladejo, Haile Ma, Wenjuan Qu, Cunshan Zhou, Bengang Wu, Uzoejinwa Benjamin Bernard, Daniel I Onwude, Xue Yang
Frying is one of the methods of processing foods, which imparts flavour, taste, colour and crispness in the fried foods. In spite an increase in the demand for fried foods by consumers all over the world, the danger posed by consuming too much fat is still a challenge. Many researchers have come up with many ideas on how to reduce the oil uptake and improve the nutritional and organoleptic qualities of foods during frying. Several pretreatments techniques applied to food materials prior to frying have been investigated by researchers in a bid to reduce the oil uptake and improve the quality parameters of fried foods...
June 28, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28657478/promoting-beliefs-in-the-inalienability-of-human-rights-by-attributing-uniquely-human-emotions-through-multiple-categorization
#11
Flavia Albarello, Richard Crisp, Monica Rubini
The combination of multiple categorization (i.e., the use of multiple criteria to define others) and human identity-the superordinate group of human beings-has recently been highlighted as a method to reduce implicit (i.e., attribution of secondary emotions) and explicit (i.e., attribution of human rights) dehumanization towards Blacks. In two studies aimed to replicate such evidence the mediating role of secondary emotions in explaining the impact of multiple and human categorization in reducing dehumanization was assessed...
June 28, 2017: Journal of Social Psychology
https://www.readbyqxmd.com/read/28645994/improvement-of-patient-wait-times-in-an-outpatient-pharmacy
#12
James P Amerine, Tippu Khan, Brett Crisp
No abstract text is available yet for this article.
July 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28645593/the-healthcare-landscape-are-doctors-agents-of-change-or-impediments-to-change
#13
Russell J Andrews, Nigel Crisp
No abstract text is available yet for this article.
June 20, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28632740/soft-bilateral-filtering-volumetric-shadows-using-cube-shadow-maps
#14
Hatam H Ali, Mohd Shahrizal Sunar, Hoshang Kolivand
Volumetric shadows often increase the realism of rendered scenes in computer graphics. Typical volumetric shadows techniques do not provide a smooth transition effect in real-time with conservation on crispness of boundaries. This research presents a new technique for generating high quality volumetric shadows by sampling and interpolation. Contrary to conventional ray marching method, which requires extensive time, this proposed technique adopts downsampling in calculating ray marching. Furthermore, light scattering is computed in High Dynamic Range buffer to generate tone mapping...
2017: PloS One
https://www.readbyqxmd.com/read/28627906/evidence-of-a-goal-directed-process-in-human-pavlovian-instrumental-transfer
#15
Tina Seabrooke, Mike E Le Pelley, Lee Hogarth, Chris J Mitchell
Cues that signal rewards can motivate reward-seeking behaviors, even for outcomes that are not currently desired. Three experiments examined this phenomenon, using an outcome-selective Pavlovian-instrumental transfer (PIT) design and an outcome devaluation procedure. In Experiment 1, participants learned to perform one response to earn crisps points and another response to earn popcorn points. One outcome was then devalued by adulterating it to make it taste unpleasant. On test, overall response choice was biased toward the outcome that had not been devalued, indicating goal-directed control...
June 19, 2017: Journal of Experimental Psychology. Animal Learning and Cognition
https://www.readbyqxmd.com/read/28624206/crispr-cas9-mediated-genome-editing-corrects-dystrophin-mutation-in-skeletal-muscle-stem-cells-in-a-mouse-model-of-muscle-dystrophy
#16
Pei Zhu, Furen Wu, Jeffrey Mosenson, Hongmei Zhang, Tong-Chuan He, Wen-Shu Wu
Muscle stem cells (MuSCs) hold great therapeutic potential for muscle genetic disorders, such as Duchenne muscular dystrophy (DMD). The CRISP/Cas9-based genome editing is a promising technology for correcting genetic alterations in mutant genes. In this study, we used fibrin-gel culture system to selectively expand MuSCs from crude skeletal muscle cells of mdx mice, a mouse model of DMD. By CRISP/Cas9-based genome editing, we corrected the dystrophin mutation in expanded MuSCs and restored the skeletal muscle dystrophin expression upon transplantation in mdx mice...
June 16, 2017: Molecular Therapy. Nucleic Acids
https://www.readbyqxmd.com/read/28590097/five-year-clinical-evaluation-of-restorations-placed-in-a-low-shrinkage-stress-composite-in-uk-general-dental-practices
#17
F J Trevor Burke, Russell J Crisp, Ali James, Louis Mackenzie, Owen Thompson, A Pal, Peter Sands, William M Palin
This paper evaluates the five year clinical evaluation of restorations formed in a low shrinkage stress resin composite material (3M ESPE Filtek Silorane, Seefeld, Germany) and placed in the general dental practices of five members of the PREP Panel, a group of UK practice-based researchers. Results indicated satisfactory performance of the material under evaluation, other than for marginal staining, which affected 60% of the restorations evaluated after five years, albeit with less than 10% of the circumference of the restorations being affected...
June 2017: European Journal of Prosthodontics and Restorative Dentistry
https://www.readbyqxmd.com/read/28573723/extruded-snacks-from-whole-wheat-supplemented-with-textured-soy-flour-effect-on-instrumental-and-sensory-textural-characteristics
#18
Arturo Rodríguez-Vidal, Héctor Eduardo Martínez-Flores, Eva González Jasso, Gonzalo Velázquez de la Cruz, Aurea K Ramírez-Jiménez, Eduardo Morales-Sánchez
The quality of extruded snacks can be affected not only by processing conditions, but also by some factors like the concentration and type of ingredients incorporated in their formulation and the working conditions used. Although the process conditions have been established with measurable textural properties, sensory qualities have not been correlated with these responses in expanded extruded snacks made with added functional ingredients. Therefore, in this study the effect of adding textured soy flour (TSF) and whole wheat flour (WWF) to refined wheat flour in the production of extruded snacks and expanded with hot air was evaluated...
June 2017: Journal of Texture Studies
https://www.readbyqxmd.com/read/28573702/examining-coping-style-and-the-relationship-between-stress-and-subjective-well-being-in-australia-s-sandwich-generation
#19
Jade E Gillett, Dimity A Crisp
OBJECTIVE: The sandwich generation represents adults, often in midlife, who care for both children and ageing parents/relatives. While the stress they experience has received some attention, little research has investigated the subjective well-being (SWB) of this population. This study examined the relationship between perceived stress and SWB and the moderating effect of coping style. METHODS: Ninety-three participants (80 women), aged 23-63 years, completed an online survey measuring perceived stress, coping strategies, life satisfaction and positive and negative affect...
June 2, 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/28571558/protein-profile-analysis-of-two-australian-snake-venoms-by-one-dimensional-gel-electrophoresis-and-ms-ms-experiments
#20
Dessi Georgieva, Diana Hildebrand, Rodrigo Simas, Monika A Coronado, Marcel Kwiatkowski, Hartmut Schlüter, Raghuvir Arni, Patrick Spencer, Christian Betzel
The Pseudechis colletti and Pseudechis butleri venoms were analyzed by 1-D gel electrophoresis, followed by mass spectrometric analysis of tryptic peptides obtained from the protein bands. Both venoms contain highly potent pharmacologically active components, which were assigned to the following protein families: basic and acidic phospholipases A2 (PLA2s), L-amino acid oxidases (LAAOs), P-III metalloproteinases (P-III SVMPs), 5'-nucleotidases (5'-NTDs), cysteine-rich secretory proteins (CRISPs), venom nerve growth factors (VNGFs) and post-synaptic neurotoxins...
May 31, 2017: Current Medicinal Chemistry
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