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Cardial regeneration

Arianna Malgieri, Eugenia Kantzari, Maria Patrizia Patrizi, Stefano Gambardella
Mesenchymal stem cells (MSCs) are multipotent adult stem cells present in all tissues, as part of the perivascular population. As multipotent cells, MSCs can differentiate into different tissues originating from mesoderm ranging from bone and cartilage, to cardiac muscle. MSCs are an excellent candidate for cell therapy because they are easily accessible, their isolation is straightforward, they can be bio-preserved with minimal loss of potency, and they have shown no adverse reactions to allogeneic versus autologous MSCs transplants...
2010: International Journal of Clinical and Experimental Medicine
Huaqin Wu, Yuanhui Hu, Yuping Zhou, Yuguang Chu
Regeneration myocardium by stem cell transplantartion has become a focus in research areas of cardial vascular disease. This review deals the role of traditional Chinese medicine in stem cell threapy of ischemic heart disease, such as mobilizing bone marrow stem cells, promoting stem cell proliferation, survival, induced them to differentiate into cardiomyocytes, and so on, showing good application prospects.
April 2009: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
I L Erokhina, M G Martynova, O M Moiseeva, O I Emel'ianova
It is known that mast cells (MC) take an active part in regeneration processes in postinfarction heart in adult rats and humans. Behaviour of population of cardial MCs has been studied 20, 60, 75 and 90 days after experimental myocardial infraction induced in 3 week-old and adult rats by ligation of left coronary artery. The density of MC of different degrees of maturity was estimated in atrium and ventricle on paraffin sections stained with Alcian blue - Safranin. Findings were compared with MC density obtained in hearts of intact rats...
2006: Tsitologiia
Frédéric Bibeau, David Azria, Marie-Christine Chateau, Cécile Borrelly, Marc Ychou, François Quenet, Philippe Rouanet
We report a case of a locally advanced cardial adenocarcinoma, occurring in a 48-year-old woman, who underwent concomitant radiotherapy and 5 FU-cis-platin based chemotherapy. Surgical tumor resection was then performed, which incidentally revealed an isolated liver nodule measuring 12 mm. This nodule was histologically characterized by an intense sinusoidal dilatation and a central venular occlusion, similar to that seen in veno-occlusive disease. This lesion was not correlated to any clinical or biological dysfunction and was finally considered as a vascular injury linked to the additive effect of the combined chemotherapy and radiotherapy...
April 2006: Gastroentérologie Clinique et Biologique
V I Shumakov, O P Shevchenko, E N Kazakov, O V Orlova, S V Gureev, L V Makarova
Relationship between levels of C-reactive protein (CRP) and neopterin and changes of left ventricular function was studied in 23 patients with heart failure (mean age 48.5+/-11.5 years) subjected to transplantation of autologous bone marrow cells (TABMC). Cells were administered intracoronary irrespective of coronary revascularization (in 11 patients) or during angioplasty (in 5 patients), intracoronary or intra-cardially during aorto coronary bypass surgery (in 7 patients). Reverse correlation was observed between left ventricular ejection fraction (EF) and stroke volume (SV) and blood plasma levels of CRP and neopterin...
2006: Kardiologiia
V B Grinevich, E I Tkachenko, Iu P Uspenskiĭ
Clinico-statistical evaluation of reparative process in 332 gastric ulcer and 294 duodenal ulcer patients revealed factors of objective value to its course. In order of significance the factors rank as follows: area of ulcer, localization, combination with certain mucosal erosions, total fasting acidity, free fasting hydrochloric acid, basal gastric secretion, cardial function, duodenogastric reflux, sex, age, number of cigarettes smoked daily. When studying treatment effects on regeneration in ulcer patients in is necessary to take into consideration basal clinico-endoscopic parameters...
1993: Terapevticheskiĭ Arkhiv
J Hustin, G Lagneaux, M Donnay, J C Debongnie
The cytologic features of dysplasia and carcinoma of the stomach are still poorly defined. In a series of 90 cases, a precise correlation could be made between smears and histologic data. Cytology was sensitive enough to allow characterization of: (1) active repair/regeneration, associated, in a number of cases, with intestinal metaplasia (slight dysplasia); the cellular atypia is minimal; (2) true dysplasia (formerly moderate and severe); this preneoplastic state is characterized by cellular atypia within clusters; and (3) true carcinomas (intestinal or diffuse type); classic criteria for malignancy are present, with a prominent lack of cell cohesiveness, though distinction from dysplasia may be very difficult...
September 1994: Acta Cytologica
D Slízová
Liver vascular bed of rat is reported to be studied by scanning electron microscopy of corrosive sections. These were prepared with commercially produced methylmetacrylate monomer which was prepolymerized and injected into the prewashed and fixed vascular bed. The injections have been provided through the left cardial ventricle or directly into the liver vessels (hepatic artery, portal vein or hepatis veines). Samples from injected liver were preleved with subsequent corrosion in 40% KOH. The obtained corrosion casts were sectioned using the operational microscope and modified to be observed by scanning electron microscope Tesla BS 300...
1991: Sborník Vědeckých Prací Lékařské Fakulty Karlovy Univerzity V Hradci Králové. Supplementum
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