keyword
MENU ▼
Read by QxMD icon Read
search

Chronic prostatitis

keyword
https://www.readbyqxmd.com/read/28809079/changes-in-the-use-of-erythropoiesis-stimulating-agents-esas-and-red-blood-cell-transfusion-in-patients-with-cancer-amidst-regulatory-and-reimbursement-changes
#1
Prasad L Gawade, Jesse A Berlin, David H Henry, Dianne Tomita, Barry D Brooks, Janet Franklin, Brian D Bradbury, Cathy W Critchlow
PURPOSE: Evaluate changes in use of erythropoiesis-stimulating agents (ESAs) and red blood cell transfusion in cancer patients receiving myelosuppressive chemotherapy following regulatory and reimbursement actions. METHODS: Calendar year patient cohorts (2005-2013) with breast, colorectal, lung, multiple myeloma, non-Hodgkin lymphoma, ovarian, or prostate cancer and receiving myelosuppressive chemotherapy were identified within the Marketscan database. Incidence of ESA treatment and transfusion were estimated in each year, as was median number of ESA administrations...
August 14, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28801952/positioning-telling-and-performing-a-male-illness-chronic-prostatitis-chronic-pelvic-pain-syndrome
#2
Nicholas Wood, Annum Qureshi, Fahim Mughal
OBJECTIVES: There is a paucity of illness accounts of men with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), despite a significant level of prevalence and burden of disease. This qualitative study thus elicited twelve accounts from men suffering with CP/CPPS. METHODS: Narrative analysis was employed, focusing primarily on narrative content. RESULTS: Three major narrative themes were identified: (1) Medical stories: Blame and shame; (2) The Erratic nature of CP/CPPS; and (3) Ongoing struggles for coping and cures and the Search for meaning...
August 11, 2017: British Journal of Health Psychology
https://www.readbyqxmd.com/read/28800293/rotating-shift-work-associated-with-obesity-in-men-from-northeastern-ontario
#3
Anne Grundy, Michelle Cotterchio, Victoria A Kirsh, Victoria Nadalin, Nancy Lightfoot, Nancy Kreiger
INTRODUCTION: While some studies have suggested associations between shift work and obesity, few have been population-based or considered multiple shift schedules. Since obesity is linked with several chronic health conditions, understanding which types of shift work influence obesity is important and additional work with more detailed exposure assessment of shift work is warranted. METHODS: Using multivariate polytomous logistic regression, we investigated the associations between shift work (evening/night, rotating and other shift schedules) and overweight and obesity as measured by body mass index cross-sectionally among 1561 men...
August 2017: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/28798031/repeated-lu-177-psma-617-radioligand-therapy-using-treatment-activities-up-to-9-3-gbq
#4
Hendrik Rathke, Frederik L Giesel, Paul Flechsig, Klaus Kopka, Walter Mier, Markus Hohenfellner, Uwe Haberkorn, Clemens Kratochwil
Current treatment protocols for (177)Lu-PSMA-617 therapies were cautiously derived from dosimetry data, but their practical appropriateness have not yet been proven clinically. We retrospectively report our clinical observations using four different treatment activities. Methods: Forty patients with advanced prostate cancer and positive uptake in PSMA-imaging were treated in fractions of 4 GBq / 80 nmol, 6 GBq / 120 nmol, 7.4 GBq / 150 nmol or 9.3 GBq / 150 nmol (177)Lu-activity / precursor-amount (n = 10, respectively) every 2 months...
August 10, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28797714/profiling-the-urinary-microbiome-in-men-with-positive-versus-negative-biopsies-for-prostate-cancer
#5
Eva Shrestha, James R White, Shu-Han Yu, Ibrahim Kulac, Onur Ertunc, Angelo M De Marzo, Srinivasan Yegnasubramanian, Leslie A Mangold, Alan W Partin, Karen S Sfanos
PURPOSE: Studies demonstrating bacterial DNA and cultivable bacteria in urine samples have challenged the clinical dogma that urine is sterile. Furthermore, studies now indicate that dysbiosis of the urinary microbiome is associated with pathological conditions. We propose that the urinary microbiome may influence chronic inflammation observed in the prostate, leading to prostate cancer development and progression. We therefore aimed to profile the urinary microbiome in men with positive versus negative biopsies for prostate cancer...
August 7, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28797620/extended-follow-up-of-patients-treated-with-bendamustine-for-lymphoid-malignancies
#6
Mara Penne, Maryam Sarraf Yazdy, Kruti Sheth Nair, Bruce D Cheson
INTRODUCTION: Bendamustine, typically in combination with rituximab, is an effective treatment for chronic lymphocytic leukemia (CLL) and B-cell non-Hodgkin lymphoma. Despite its acceptable short-term toxicity profile, long-term toxicities are less well established. This study investigated the long-term adverse effects of bendamustine and responses to subsequent treatments. PATIENTS AND METHODS: Charts of 194 patients were retrospectively reviewed; 54% had received prior treatment (76% attained complete response [CR] or partial response [PR])...
June 30, 2017: Clinical Lymphoma, Myeloma & Leukemia
https://www.readbyqxmd.com/read/28793363/falls-a-fear-of-falling-and-related-factors-in-older-adults-with-complex-chronic-disease
#7
JuHee Lee, MoonKi Choi, Chang Oh Kim
AIM AND OBJECTIVES: To identify factors influencing falls and the fear of falling among older adults with chronic diseases in Korea. BACKGROUND: The fear of falling and falls in older adults are significant health problems towards which healthcare providers should direct their attention. Further investigation is needed to improve nursing practice specifically decreasing risk of falls and the fear of falling in Korea. DESIGN: Descriptive, cross-sectional survey...
August 9, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28789948/burden-of-multiple-chronic-conditions-among-urologic-cancer-patients
#8
Tullika Garg, Amanda J Young, Korey A Kost, John F Danella, Sharon Larson, Matthew E Nielsen, H Lester Kirchner
PURPOSE: To describe age, multiple chronic condition (MCC) profiles, and health system contact in urologic cancer patients. MATERIALS & METHODS: Using Geisinger Health System electronic health records, we identified adult primary care patients and a subset with at least one urology encounter between 2001-2015. Agency for Healthcare Research and Quality Chronic Condition Indicator and Clinical Classifications Software tools were applied to International Classification of Diseases, Ninth Revision (ICD-9) codes to identify chronic conditions...
August 5, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28770549/therapy-related-longitudinal-brain-perfusion-changes-in-patients-with-chronic-pelvic-pain-syndrome
#9
Christian Weisstanner, Livio Mordasini, George N Thalmann, Rajeev K Verma, Christian Rummel, Andrea Federspiel, Thomas M Kessler, Roland Wiest
BACKGROUND: The imaging method most frequently employed to identify brain areas involved in neuronal processing of nociception and brain pain perception is blood oxygenation level-dependent (BOLD) magnetic resonance imaging (MRI). Arterial spin labelling (ASL), in contrast, offers advantages when slow varying changes in brain function are investigated. Chronic pelvic pain syndrome (CPPS) is a disorder of, mostly, young males that leads to altered pain perceptions in structures related to the pelvis...
August 3, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28768262/clinical-evaluation-of-urine-prostatic-exosomal-protein-in-the-diagnosis-of-chronic-prostatitis
#10
Xiaojun Li, Ting Jiang, Feng Liu, Xuefeng Shao, Ye Xu, Weixin Sheng, Wei Sun
OBJECTIVE: To evaluate the clinical potential of urine prostatic exosomal protein (PSEP) as a diagnostic biomarker of chronic prostatitis (CP). Materials andmethods: Using an enzyme-linked immunosorbent assay kit, urine PSEP levels were detected in 103 control cases as well as 283 cases of CP, with 82 cases fulfilling the definition of the USA National Institutes of Health category II (NIH-II), 108 cases of NIH-IIIa and 93 cases of NIH-IIIb. The values of age, body mass index, prostate volume, serum prostatic specific antigen (PSA) urine PSEP levels, and seminal parameters were analyzed...
July 29, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28767087/novel-methylselenoesters-as-antiproliferative-agents
#11
Nuria Díaz-Argelich, Ignacio Encío, Daniel Plano, Aristi P Fernandes, Juan Antonio Palop, Carmen Sanmartín
Selenium (Se) compounds are potential therapeutic agents in cancer. Importantly, the biological effects of Se compounds are exerted by their metabolites, with methylselenol (CH₃SeH) being one of the key executors. In this study, we developed a new series of methylselenoesters with different scaffolds aiming to modulate the release of CH₃SeH. The fifteen compounds follow Lipinski's Rule of Five and with exception of compounds 1 and 14, present better drug-likeness values than the positive control methylseleninic acid...
August 2, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28762547/correlation-of-inflammatory-mediators-in-prostatic-secretion-with-chronic-prostatitis-and-chronic-pelvic-pain-syndrome
#12
T R Huang, W Li, B Peng
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common clinical syndrome, and the mechanisms underlying the relationship between CP/CPPS and ED are still unclear. This study aimed to investigate the differential expression of 40 inflammatory mediators in patients with CP/CPPS and to demonstrate whether these mediators related to the severity of erectile function. Eighty cases of patients with CP/CPPS were selected, including 40 cases of IIIA and 40 cases of IIIB, with 20 cases of healthy men as controls...
August 1, 2017: Andrologia
https://www.readbyqxmd.com/read/28754796/a-prospective-study-of-chronic-inflammation-in-benign-prostate-tissue-and-risk-of-prostate-cancer-linked-pcpt-and-select-cohorts
#13
Elizabeth A Platz, Ibrahim Kulac, John R Barber, Charles G Drake, Corinne E Joshu, William G Nelson, M Scott Lucia, Eric A Klein, Scott M Lippman, Howard L Parnes, Ian M Thompson, Phyllis J Goodman, Catherine M Tangen, Angelo M De Marzo
BACKGROUND: We leveraged two trials to test the hypothesis of an inflammation-prostate cancer link prospectively in men without indication for biopsy. METHODS: Prostate Cancer Prevention Trial (PCPT) participants who had an end-of-study biopsy performed per protocol that was negative for cancer and who subsequently enrolled in the Selenium and Vitamin E Cancer Prevention Trial (SELECT) were eligible. We selected all 100 cases and sampled 200 frequency-matched controls and used PCPT end-of-study biopsies as "baseline"...
July 28, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28753805/the-urinary-tract-microbiome-in-health-and-disease
#14
REVIEW
Isabel M Aragón, Bernardo Herrera-Imbroda, María I Queipo-Ortuño, Elisabeth Castillo, Julia Sequeira-García Del Moral, Jaime Gómez-Millán, Gozde Yucel, María F Lara
CONTEXT: The urinary tract, previously considered a sterile body niche, has emerged as the host of an array of bacteria in healthy individuals, revolutionizing the urology research field. OBJECTIVE: To review the literature on microbiome implications in the urinary tract and the usefulness of probiotics/prebiotics and diet as treatment for urologic disorders. EVIDENCE ACQUISITION: A systematic review was conducted using PubMed and Medline from inception until July 2016...
November 14, 2016: European Urology Focus
https://www.readbyqxmd.com/read/28751992/prostatic-like-syndrome-in-a-woman-with-chronic-lymphocytic-leukemia-sequential-kinase-inhibitor-therapy
#15
Diego Velasco-Rodríguez, Miguel Piris-Villaespesa, Carmen Soteras, Ana Vallés, José Antonio García-Marco, José Antonio García-Vela
Chronic lymphocytic leukemia (CLL) is an incurable lymphoproliferative disorder with a heterogeneous genetic and clinical course. Two kinase inhibitors, ibrutinib and idelalisib, have demonstrated achievement of complete and durable remissions in relapse/refractory genetically unselected CLL patients. We present a case of relapsed CLL with extensive disease and hourglass deformity of urinary bladder as a result of the compression of two extraperitoneal paravesical soft tissue bulky masses, with excellent response to sequential kinase inhibitor therapy...
2017: Case Reports in Hematology
https://www.readbyqxmd.com/read/28735516/dnmt1-regulates-il-6-and-tgf-%C3%AE-1-induced-epithelial-mesenchymal-transition-in-prostate-epithelial-cells
#16
Hui Xu, Yanbo Chen, Qi Chen, Huan Xu, Yanxia Wang, Jiao Yu, Juan Zhou, Zhong Wang, Bing Xu
Multiple factors have been considered to play a role in the development of benign prostatic hyperplasia (BPH), including chronic inflammation, hormones, and epithelial-mesenchymal transition (EMT). Inflammation is regarded as one of the potential inducers of EMT. However, the mechanisms, modulating pro-inflammatory factors (IL-6 and TGF-β1) induce EMT features, have not yet been studied in BPH. In this study, we investigated whether DNA methyltransferases1 (DNMT1) could regulate IL-6 and TGF-β1 induce EMT...
May 3, 2017: European Journal of Histochemistry: EJH
https://www.readbyqxmd.com/read/28732370/silibinin-an-old-drug-for-hematological-disorders
#17
REVIEW
Hai Zou, Xing-Xing Zhu, Guo-Bing Zhang, Yuan Ma, Yi Wu, Dong-Sheng Huang
Silibinin (silybin), a non-toxic natural polyphenolic flavonoid, is the principal and the most biologically active component of silymarin. It is efficient in the treatment of acute and chronic liver disorders caused by toxins, drug, alcohol, hepatitis, and gall bladder disorders. Further, in our previous studies, we explored the anti-cancer efficacy in common cancers, such as lung, prostatic, colon, breast, bladder, as well as, hepatocellular carcinoma. Interestingly, silibinin is still not solely limited to the treatment of these diseases...
July 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28725596/utility-of-trigger-point-injection-as-an-adjunct-to-physical-therapy-in-men-with-chronic-prostatitis-chronic-pelvic-pain-syndrome
#18
Nicholas N Tadros, Anup B Shah, Daniel A Shoskes
BACKGROUND: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is often associated with pelvic floor muscle spasm. While pelvic floor physical therapy (PFPT) is effective, some men are unable to resolve their symptoms and have residual trigger points (TPs). TP injection has been used for treatment in several neuromuscular pain syndromes. The objective of this study was to examine the efficacy and side effects of TP injection in men with CP/CPPS and pelvic floor spasm refractory to PT...
June 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28724322/predictors-of-urinary-incontinence-between-abdominal-obesity-and-non-obese-male-adults
#19
Dongmei Li, Yi Xu, Qingbin Nie, Yan Li, Gengsheng Mao
OBJECTIVES: To investigate factors that may be associated with urinary incontinence (UI) in abdominal obese and non-obese adult males. METHODS: Data were analyzed for 2671 men (≥40 years of age) who participated in the National Health and Nutrition Examination Survey (2005-2008). We define abdominal obesity as a waist circumference >102 cm. Men with Incontinence Severity Index ≥3 were defined as having UI. Logistic regression analyses were used to identify factors associated with stress and urge UI...
July 20, 2017: Postgraduate Medicine
https://www.readbyqxmd.com/read/28723662/acetyl-lupeolic-acid-inhibits-akt-signaling-and-induces-apoptosis-in-chemoresistant-prostate-cancer-cells-in-vitro-and-in-vivo
#20
Claudia Schmidt, Cornelia Loos, Lu Jin, Michael Schmiech, Christoph Q Schmidt, Menna El Gaafary, Tatiana Syrovets, Thomas Simmet
The triterpenoid acetyl-lupeolic acid (ac-LA) isolated from the oleogum resin of Boswellia carterii reduced the viability of a panel of cancer cell lines more efficiently than lupeol. There was no detectable intracellular conversion of ac-LA to lupeol and vice versa. In contrast to docetaxel, ac-LA did not induce selection of treatment-resistant cancer cells. By various parameters including DNA fragmentation, ac-LA was shown to induce apoptosis in androgen-independent PC-3 cells, whereas in MDA-MB-231 breast cancer cells, ac-LA led to cell accumulation in the G2/M phase of the cell cycle, but not to apoptosis...
July 8, 2017: Oncotarget
keyword
keyword
83512
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"