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Negative pressure wound therapy

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https://www.readbyqxmd.com/read/28817237/dysregulation-of-wound-healing-mechanisms-in-diabetes-and-the-importance-of-negative-pressure-wound-therapy-npwt
#1
Mogher Khamaisi, Sarit Balanson
Diabetes is a serious disease with severe side effects and comorbidities. Diabetic foot with its chronic non-healing ulcers, or diabetic food ulcers (DFU) as they are commonly called, can be devastating, even leading to amputation. Many therapies exist to assist and improve wound healing. One exciting discovery is the use of negative pressure wound therapy (NPWT) as an adjunct to standard treatment. Few studies have substantively explored the molecular mechanisms of NPWT and why we see improved wound healing, a concept that demands more research...
August 17, 2017: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/28816717/comparison-of-negative-pressure-wound-therapy-and-conventional-therapy-for-cranial-bone-exposed-wounds-in-rabbits
#2
Lin Chen, Guorui Li, Sha Liu, Xianjie Ma, Xueyong Li, Yingjun Su, Shuzhong Guo
BACKGROUND: Bone-exposed wounds with intact or defected periosteum are difficult to heal. To provide relevant experimental evidence for guidance of clinical therapy, we established a rabbit model to compare the efficacies of negative pressure wound therapy (NPWT) and conventional guaze dressing therapy on the healing of cranial bone-exposed wounds. METHODS: Full-thickness excisional circular wounds of 2.0 cm in diameter with exposed bones covered with or without periosteum were created at the parietal regions in 88 rabbits that were further randomly divided into the following treatment groups: periosteum-intact wounds treated with conventional vaseline gauze dressings (P + Control group), periosteum-intact wounds treated with NPWT (P + NPWT group), periosteum-lacking wounds treated with conventional vaseline gauze dressings (P-Control group), and periosteum-lacking wounds treated with NPWT (P-NPWT group)...
August 14, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28807639/a-survey-of-caesarean-section-surgical-site-infections-with-pico%C3%A2-single-use-negative-pressure-wound-therapy-system-in-high-risk-patients-in-england-and-ireland
#3
R J Searle, D Myers
This article reports audit data from the introduction of the PICO™ System for caesarean section patients with high body mass index (BMI) in four hospitals in the UK and Ireland. PICO was used on closed surgical incisions following caesarean section in 399 patients with BMI ≥35kg/m(2). Thirty-six out of 399 patients (9.0%) developed signs of surgical site infection (SSI), a rate lower than a previously reported incidence of 19.3% in a similar population. The readmission incidence was 0.8%. Therefore the use of PICO on closed surgical incisions may be associated with low incidence of SSI and readmission in this high-risk group...
August 11, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28801082/-how-to-videos-improve-residents-performance-of-essential-perioperative-electronic-medical-records-and-clinical-tasks
#4
Veronica Zoghbi, Robert C Caskey, Kristoffel R Dumon, Jacqueline M Soegaard Ballester, Ari D Brooks, Jon B Morris, Daniel T Dempsey
OBJECTIVE: The ability to use electronic medical records (EMR) is an essential skill for surgical residents. However, frustration and anxiety surrounding EMR tasks may detract from clinical performance. We created a series of brief, 1-3 minutes "how to" videos demonstrating 7 key perioperative EMR tasks: booking OR cases, placing preprocedure orders, ordering negative-pressure wound dressing supplies, updating day-of-surgery history and physical notes, writing brief operative notes, discharging patients from the postanesthesia care unit, and checking vital signs...
August 8, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28797553/negative-pressure-wound-therapy
#5
REVIEW
Bryden J Stanley
Open wounds are regularly addressed in veterinary medicine and can be challenging to manage, especially when there is significant loss of full-thickness skin. Traditional wound dressings are being replaced by modern synthetic materials, biologic wound dressings, and mechanical technologies to augment healing. Negative pressure wound therapy (NPWT) is one of the most successful mechanical adjuncts to wound healing. Experience with NPWT in veterinary medicine is not as extensive as in human medicine but reports have been positive...
August 7, 2017: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/28795891/experience-using-closed-incision-negative-pressure-wound-therapy-in-sternotomy-patients
#6
B Philip, P McCluskey, J Hinchion
OBJECTIVE: Postoperative delayed wound healing, surgical site infections (SSIs), and other wound complications are associated with increased morbidity and health-care costs. In cardiothoracic surgery, wound complications can have life-threatening consequences. In recent years, negative pressure wound therapy (NPWT) has been applied over closed surgical incisions to help reduce tension and protect from external contamination. We report our initial experiences using a closed incision negative pressure therapy (ciNPT) over clean, closed sternotomy incisions at an Irish tertiary referral centre...
August 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28795884/results-of-directly-applied-activated-carbon-cloth-in-chronic-wounds-a-preliminary-study
#7
H S Scheer, M Kaiser, U Zingg
OBJECTIVE: Activated carbon (AC) has been used in wound therapy as an active substance inside dressings. Applying AC directly on a wound is a new concept. The aim of this study was to analyse the outcomes of chronic wounds which were managed with directly applied activated carbon knitted cloth (ACC, Zorflex) in Swiss patients. METHOD: A retrospective analysis of the records of all patients with chronic wounds treated with ACC between 1 October 2013 and 31 December 2015 in an outpatient wound clinic...
August 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28792822/topical-oxygenation-therapy-in-wound-care-are-patients-getting-enough
#8
Sharon Hunt
Wound management is a major burden on today's healthcare provider, both clinically with regard to available resources and financially. Most importantly, it has a significant impact on the patient's quality of life and experience. Within the field of wound care these pressures, alongside an ageing population, multiple comorbidities, disease processes and negative lifestyle choices, increase incidences of reduced skin integrity and challenging wounds. In an attempt to meet these challenges alternative, innovative therapies are being explored to support the wound healing process...
August 10, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28792821/negative-pressure-wound-therapy-and-nurse-education
#9
Amy Cray
BACKGROUND: there can be serious consequences for patients if negative pressure wound therapy (NPWT) is performed incorrectly and patient safety must be paramount. The existing literature was found to mainly concentrate on the use of the technology from the patient perspective. This article examines the opinions of nurses who apply the therapy. METHOD: five staff nurses from different areas with differing experience levels were interviewed in a semi-structured manner...
August 10, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28790274/-prevention-and-treatment-of-mediastinitis-following-cardiac-surgery
#10
Kojiro Furukawa, Shigeki Morita
Mediastinitis after cardiac surgery occurs about 1% of the time and is associated with adverse effects on both short- and long-term outcomes. Therefore, prevention of mediastinitis is very important. However, when this complication occurs, a radical cure should be performed using a safe and reliable method. Many pre-, intra-, and post-operative risk factors have been reported. Perioperative management based on an understanding of the pathological condition that causes this complication is an effective prevention strategy...
July 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28781059/debridement-techniques-and-non-negative-pressure-wound-therapy-wound-management
#11
REVIEW
Elizabeth Thompson
The importance of initial wound classification and daily reevaluation of wound stage cannot be understated. Products available to enhance healing are categorized based on the stage of wound healing to which they exert their effects. After patient stability has been verified, thorough debridement is critical in order to create an environment conducive for healing. The wound environment of acute and chronic wounds differs greatly, often requiring different management approaches.
August 4, 2017: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/28777906/can-amputation-be-prevented-in-diabetic-foot-interdisciplinary-approach-to-diabetic-foot-a-case-report
#12
Ali Erdal Gunes, Maide Cimsit
Diabetic foot ulcers may result in loss of an extremity and may even lead to mortality. The use of comprehensive foot care programs which include early screening and evaluation of problems, foot care education, preventive therapy and referral to specialists has been shown to reduce amputation rates by 49-85 [percent]. A 51-year-old woman with Type 2 diabetes under surveillance for nine months was referred from the emergency department. She presented with an entirely inflamed right foot with ulcer covering two-thirds proximal of the foot for 30 days' duration...
March 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777123/improvised-skin-graft-for-a-large-superficial-hematoma-a-case-study
#13
Nicole Kindel
BACKGROUND: Management of a hematoma is challenging when its size is substantial. CASE: This case report describes the successful surgical treatment of a large, superficial hematoma with an improvised skin graft and negative pressure wound therapy. CONCLUSIONS: We have found that using the patient's own skin for a skin graft may provide adequate wound coverage and decrease healing time. This method also eliminates the need for creating a donor site...
August 2, 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28763910/-influence-of-different-inner-dressings-in-negative-pressure-wound-therapy-on-escharectomy-wound-of-full-thickness-burn-rabbits
#14
J H Lin, J Chen, D J Xue, W X Huang, G L Su
Objective: To explore the influence of different inner dressings in negative-pressure wound therapy (NPWT) on escharectomy wound of full-thickness burn rabbits. Methods: Eighteen Japanese white rabbits were inflicted with full-thickness burn on unilateral back. They were divided into polymer dressing group (PD), biological dressing group (BD), and silver biological dressing group (SBD), according to the random number table, with 6 rabbits in each group. On 3 days post burn, the wounds were performed with escharectomy, and then wounds of rabbits in group PD were covered with polyurethane foam...
July 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28759428/negative-pressure-wound-therapy-for-patients-with-complex-abdominal-wounds
#15
Ahmet Bilgi, Fazilet Zumrut Biber Muftuler, Levent Akman, Emin Ilker Medine, Pinar Tonbaklar Bilgi, Ozge Kozgus Guldu, Sevki Goksun Gokulu, Volkan Tekin, Mustafa Cosan Terek
BACKGROUND: Research on treatment alternatives that improve wound healing is an ever-evolving area in medicine, and a wound healing agent that carries minimal pain, discomfort, and scarring for patients with burn wounds, venous and decubitis ulcers, traumatic wounds, and many others is needed. The phases of wound healing include homeostasis, inflammation, migration, proliferation, and maturation. Adeps suillus (axonge) is known as a therapeutic agent for skin diseases and mainly consists of triglycerides...
July 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28759427/negative-pressure-wound-therapy-for-patients-with-complex-abdominal-wounds
#16
Zhi Wang, Ming Bai, Xiao Long, Ru Zhao, Xiaojun Wang
The combination of open abdominal wounds and intra-abdominal infections is challenging to treat and often results in critical illness associated with high mortality. OBJECTIVE: The aim of this study is to evaluate the feasibility of using negative pressure wound therapy (NPWT) to manage complex abdominal wounds and summarize relevant treatment experiences. MATERIALS AND METHODS: A retrospective analysis of records from April 2012 to May 2015 identified 13 hospitalized patients with open abdominal wounds complicated by intra-abdominal infections...
July 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28756380/a-case-of-deep-infection-after-instrumentation-in-dorsal-spinal-surgery-the-management-with-antibiotics-and-negative-wound-pressure-without-removal-of-fixation
#17
Mauro Dobran, Fabrizio Mancini, Davide Nasi, Massimo Scerrati
Until today the role of spinal instrumentation in the presence of a wound infection has been widely discussed and recently many authors leave the hardware in place with appropriate antibiotic therapy. This is a case of a 65-year-old woman suffering from degenerative scoliosis and osteoporotic multiple vertebral collapses treated with posterior dorsolumbar stabilisation with screws and rods. Four months later, skin necrosis and infection appeared in the cranial wound with exposure of the rods. A surgical procedure of debridement of the infected tissue and package with a myocutaneous trapezius muscle flap was performed...
July 28, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28742785/an-effective-negative-pressure-wound-therapy-1-compatible-local-antibiotic-delivery-device
#18
Ben C C Rand, Joseph C Wenke
OBJECTIVES: The current clinical standard for local antibiotic depot is polymethylmethacrylate (PMMA) beads. Unfortunately, these are not ideal and negative pressure wound therapy (NPWT) reduces their limited effectiveness. Recently, a chitosan sponge has been shown to be an effective carrier of antibiotics. Since it acts as a delivery vehicle with increased wound contact area instead of an antibiotic depot, it may be more effective. The objectives of this study are to determine if 1) a chitosan sponge would be more effective than PMMA beads as a local antibiotic delivery device and 2) the chitosan sponge remains an effective method of delivery when used in conjunction with NPWT...
July 24, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28734659/comparative-effectiveness-study-between-negative-pressure-wound-therapy-and-conventional-wound-dressing-on-perforator-flap-at-the-chinese-tertiary-referral-teaching-hospital
#19
Regis Ernest Mendame Ehya, Yong Zhao, Xun Zheng, Wanrong Yi, Guy-Armel Bounda, Zonghuan Li, Weidong Xiao, Aixi Yu
BACKGROUND: Perforator flap techniques with conventional wound dressing have being extensively used in the management of soft-tissue defects. However; the flap's survival rate is not always guaranteed and the wound healing time always long. The aim of this study was to investigate the clinical effectiveness use of a freshly transplanted perforator flap in conjunction with Vacuum-assisted closure (VAC) for better clinical outcomes. METHODS: A prospective, randomized, effectiveness study comparing the clinical outcomes of VAC versus traditional wrap and bandages for the treatment of open wounds that required hospital admission and operative debridement using perforator flaps, was carried out from March 1, 2014 to March 31, 2016 at Wuhan University Zhongnan Hospital...
July 12, 2017: Journal of Tissue Viability
https://www.readbyqxmd.com/read/28732537/negative-pressure-wound-therapy-versus-modified-barker-vacuum-pack-as-temporary-abdominal-closure-technique-for-open-abdomen-management-a-four-year-experience
#20
Giulia Montori, Niccolò Allievi, Federico Coccolini, Leonardo Solaini, Luca Campanati, Marco Ceresoli, Paola Fugazzola, Roberto Manfredi, Stefano Magnone, Matteo Tomasoni, Luca Ansaloni
BACKGROUND: We reviewed our experience with patients presenting with trauma and peritonitis who underwent an open abdomen (OA) procedure, and compared outcomes between Negative Pressure Wound Therapy (NPWT) and a modified Barker Vacuum Pack (mBVP) technique. METHODS: In this descriptive study, we retrospectively analyzed data regarding all patients who underwent OA for intra-abdominal sepsis or abdominal trauma at our Centre from January 2012 to December 2015. Demographic data, co-morbidities, indications to surgery, intra-operative details and Björck classification grade were considered...
July 21, 2017: BMC Surgery
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