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Migraine tests

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https://www.readbyqxmd.com/read/28731365/chemical-composition-and-antimigraine-activity-of-essential-oil-of-angelicae-dahuricae-radix
#1
Jingbo Sun, He Li, Jinghui Sun, Huimin Liu, Jianguang Chen, Chunmei Wang
The aim of this study was to explore the chemical composition and the effect of essential oil of Angelicae dahuricae radix on a nitroglycerin (NTG)-induced rat model of migraine. The CO2 supercritical fluid extraction method was optimized for the extraction of essential oil of A. dahuricae radix (EOAD) and its chemical composition was determined. The migraine model was established by subcutaneous injection of NTG (10 mg/kg) 1 h after the last administration of EOAD. The therapeutic effect of EOAD and its underlying mechanism were assessed by monitoring behavioral changes, levels of nitric oxide (NO) in serum and brain tissues, plasma levels of calcitonin gene-related peptide (CGRP) and endothelin (ET), and ET/NO ratio...
July 21, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28730563/functional-connectivity-and-cognitive-impairment-in-migraine-with-and-without-aura
#2
Viviana Lo Buono, Lilla Bonanno, Francesco Corallo, Laura Rosa Pisani, Riccardo Lo Presti, Rosario Grugno, Giuseppe Di Lorenzo, Placido Bramanti, Silvia Marino
BACKGROUND: Several fMRI studies in migraine assessed resting state functional connectivity in different networks suggesting that this neurological condition was associated with brain functional alteration. The aim of present study was to explore the association between cognitive functions and cerebral functional connectivity, in default mode network, in migraine patients without and with aura, during interictal episodic attack. METHODS: Twenty-eight migraine patients (14 without and 14 with aura) and 14 matched normal controls, were consecutively recruited...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28730399/optical-coherence-tomography-angiography-findings-in-susac-s-syndrome-a-case-report
#3
Rodolfo Mastropasqua, Lisa Toto, Alfonso Senatore, Alessandro D'Uffizi, Piergiorgio Neri, Cesare Mariotti, Marica Tina Maccarone, Luca Di Antonio
PURPOSE: To report clinical features of Susac's syndrome (SS) using optical coherence tomography angiography (OCTA). METHODS: Case report. RESULTS: A 25-year-old Caucasian female with a history of non-pulsatile migraine, tinnitus, and verbal apraxia complaining of peripheral scotoma in left eye due to branch retinal arteriole occlusion (BRAO) was diagnosed as having SS after audiometric test, brain magnetic resonance imaging, and multimodal retinal imaging...
July 20, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28729175/brain-targeting-efficiency-of-antimigrain-drug-loaded-mucoadhesive-intranasal-nanoemulsion
#4
Ebtsam M Abdou, Soha M Kandil, Hala M F El Miniawy
Zolmitriptan (ZT) is a well-tolerated drug in migraine treatment suffering from low bioavailability due to low amount of the drug that reaches the brain after oral and nasal delivery. Development of new nasal mucoadhesive nanoemulsion formulation for zolmitriptan may success in delivering the drug directly from the nose to the brain to achieve rapid onset of action and high drug concentration in the brain which is required for treatment of acute migraine. ZT mucoadhesive nanoemulsion were prepared and characterized for drug content, zeta potential, particle size, morphology, residence time and permeation through the nasal mucosa...
July 17, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28727225/intact-blood-brain-barrier-during-spontaneous-attacks-of-migraine-without-aura-a-3t-dce-mri-study
#5
F M Amin, A Hougaard, S P Cramer, C E Christensen, F Wolfram, H B W Larsson, M Ashina
BACKGROUND AND PURPOSE: The integrity of the blood-brain barrier (BBB) has been questioned in migraine, but BBB permeability has never been investigated during spontaneous migraine attacks. In the present study, BBB permeability during spontaneous attacks of migraine without aura was investigated compared to an interictal state. METHODS: Seventy-four patients suffering from migraine without aura were recruited to participate in this cross-sectional dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) study...
July 20, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28723686/population-based-study-on-the-epidemiology-of-m%C3%A3-ni%C3%A3-re-s-disease
#6
Saskia G Bruderer, Daniel Bodmer, Nadja A Stohler, Susan S Jick, Christoph R Meier
BACKGROUND AND OBJECTIVE: Ménière's disease (MD) is a disorder of the inner ear typically showing recurrent acute episodes of vertigo, hearing loss, and tinnitus. Epidemiologic studies on MD are scarce. We assessed the incidence rates (IRs) of MD and describe the characteristics of MD cases, comparing them to control patients without recorded evidence of MD. STUDY DESIGN: We conducted a retrospective population-based follow-up study and a nested case-control analysis using data from the UK-based Clinical Practice Research Datalink...
July 20, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28690531/stem-cells-in-the-treatment-of-refractory-chronic-migraines
#7
Alexander Mauskop, Kenneth O Rothaus
BACKGROUND: Autologous adipose-derived stromal vascular fraction (SVF), which is rich in mesenchymal stromal cells, has been reported to be effective for the treatment of trigeminal neuropathic pain and chronic migraine and tension-type headaches. It is possible that stem cell activity targets neurogenic inflammation, which is a well-documented aspect of migraine pathogenesis. METHODS: Adult patients with severe migraine-related disability as measured by the Migraine Disability Assessment (MIDAS) score who failed botulinum toxin injections and at least 3 prophylactic drugs were included in this study...
May 2017: Case Reports in Neurology
https://www.readbyqxmd.com/read/28682840/functional-balance-deterioration-on-daily-activities-in-patients-with-migraine-a-controlled-study
#8
Gabriela F Carvalho, Lidiane L Florencio, Carina F Pinheiro, Fabiola Dach, Marcelo E Bigal, Débora Bevilaqua-Grossi
OBJECTIVE: This study aimed to assess functional activities in different subgroups of patients with migraine. DESIGN: One-hundred forty subjects were uniformly divided into the following four groups: headache-free controls, migraine with aura, without aura, and chronic migraine. Subjects performed the tests walk across, tandem walk, sit to stand, and step up and over at the Balance Master system (Neurocom). RESULTS: All migraine groups had slower velocity and shorter step length at the walk across test (P < 0...
July 7, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28677996/headache-in-pediatric-and-adolescent-patients-with-chronic-kidney-disease-with-and-without-hemodialysis-a-comparative-cohort-study
#9
Miriam Davidovits, Tal Eidlitz Markus
Background Several studies have reported dialysis-related headache in adults. We investigated headache and its characteristics in pediatric and adolescent patients with chronic kidney disease and patients treated with dialysis, and compared characteristics of patients with and without headache in the entire cohort and separately among dialysis and among chronic kidney disease patients. Methods Patients and their parents who attended a nephrology clinic and hemodialysis unit were interviewed regarding the existence of headache and its characteristics...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28666316/two-year-test-retest-reliability-in-high-school-athletes-using-the-four-and-two-factor-impact-composite-structures-the-effects-of-learning-disorders-and-headache-migraine-treatment-history
#10
Benjamin L Brett, Gary S Solomon, Jennifer Hill, Philip Schatz
Objective: This study examined the test-retest reliability of the four- and two-factor structures (i.e., Memory and Speed) of ImPACT over a 2-year interval across multiple groups with premorbid conditions, including those with a history of special education or learning disorders (LD; n = 114), treatment history for headache/migraine (n = 81), and a control group (n = 792). Methods: Nine hundred and eighty seven high school athletes completed baseline testing using online ImPACT across a 2-year interval...
June 28, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28665211/effects-of-omega-3-fatty-acids-on-the-frequency-severity-and-duration-of-migraine-attacks-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#11
Leila Maghsoumi-Norouzabad, Anahita Mansoori, Reza Abed, Farideh Shishehbor
The present systematic review with meta-analysis of randomized controlled trials (RCTs) aimed to analyze the effectiveness of omega-3 fatty acids on the frequency, severity, and duration of migraine. This systematic review was performed by searching several databases for controlled clinical trials. Of the 13 trials, five, two, and three RCTs met the eligibility criteria to evaluate the efficacy of omega-3 on the frequency, duration, and severity of migraine attacks, respectively. The Jadad scale was used to evaluate the risk of bias analysis...
June 30, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/28660561/hormonal-effect-on-the-relationship-between-migraine-and-female-sexual-dysfunction
#12
Vasfiye Burcu Dogan, Hediye Dagdeviren, Ahmet Dirican, Ayten Ceyhan Dirican, Nurhan Kaya Tutar, Vidan Ayse Yayla, Hüseyin Cengiz
It is not a well-established finding in migraine that female sexual dysfunction (FSD) emerging as a natural course of disease, as a result of accompanying depression/anxiety, or an underlying endocrinological abnormality. Our aim is evaluating the relationship among frequency and severity of migraine, FSD, depression, anxiety, and related hormones in migrainous women. We examined 80 migrainous female and 62 controls cross sectionally. Beck Depression and Anxiety Inventories, Female Sexual Dysfunction Inventory, Migraine Disability Assessment Test, and hormonal analysis were done...
June 28, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28659861/the-effect-of-systemic-nitroglycerin-administration-on-the-kynurenine-pathway-in-the-rat
#13
Gábor Nagy-Grócz, Klaudia F Laborc, Gábor Veres, Attila Bajtai, Zsuzsanna Bohár, Dénes Zádori, Annamária Fejes-Szabó, Eleonóra Spekker, László Vécsei, Árpád Párdutz
The primary headache disorders include migraine, which is one of the most frequent neurological disorders, which influences more than 14% of the whole population. Despite the research efforts, its exact pathomechanism is not fully revealed, but evidence points to the role of glutamate and its receptors. Kynurenic acid is an endogenous glutamate receptor antagonist produced by the kynurenine pathway (KP). Tryptophan 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) convert l-tryptophan to N-formyl-l-kynurenine, to be further transformed to l-kynurenine...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28653369/recognition-of-chronic-migraine-by-medicine-trainees-a-cross-sectional-survey
#14
Priyanka Yadav, Alec L Bradley, Jonathan H Smith
OBJECTIVE: Chronic migraine is a diagnosis that can be abstracted through the clinical history, although some providers may struggle in properly applying diagnostic criteria. We aimed to learn how well medicine trainees would be able to recognize the diagnostic criteria for chronic migraine and apply that medical knowledge to case vignettes illustrating different symptom interpretation strategies of the identical information. METHODS: An electronic, anonymous and multiple-choice response questionairre assessing selected trainee characteristics, headache case vignettes, and chronic migraine diagnostic criteria was distributed to all regional medicine program directors and coordinators in Kentucky and surrounding states...
June 26, 2017: Headache
https://www.readbyqxmd.com/read/28643603/stroke-like-migraine-attacks-after-radiation-therapy-syndrome-case-report-and-review-of-the-literature
#15
Achint K Singh, Bundhit Tantiwongkosi, Anna-Marieta Moise, Wilson B Altmeyer
A 26-year-old female presented with vision loss accompanied by migraine-like headaches. A contrast-enhanced magnetic resonance imaging of the brain was performed which revealed findings suggestive of stroke-like migraine attacks after radiation therapy (SMART) syndrome. SMART syndrome is a delayed complication of brain radiation characterized by neurologic symptoms including migraine-like headaches, seizures, and hemispheric impairment. The purpose of this article is to make the readers aware of this rare complication of brain irradiation...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/28641450/musculoskeletal-dysfunction-in-migraine-patients
#16
Kerstin Luedtke, Wiebke Starke, Arne May
Objective The aim of this project was to evaluate the prevalence and pattern of musculoskeletal dysfunctions in migraine patients using a rigorous methodological approach and validating an international consensus cluster of headache assessment tests. Methods A physiotherapist, blinded towards the diagnosis, examined 138 migraine patients (frequent episodic and chronic), recruited at a specialised headache clinic, and 73 age and gender matched healthy controls following a standardised protocol. Eleven tests, previously identified in an international consensus procedure, were used to evaluate cervical and thoracic musculoskeletal dysfunctions...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28636737/is-there-an-association-between-migraine-and-allergic-rhinitis
#17
Işıl Adadan Güvenç, Mustafa Acar, Nuray Bayar Muluk, Nagehan Erdogmus Kucukcan, Cemal Cingi
We conducted a prospective study to evaluate nasal signs and symptoms and to perform allergen-specific immunoglobulin E (IgE) testing to investigate the relationship between migraine and allergic rhinitis. Our study group consisted of 40 patients diagnosed with migraine-22 men and 18 women, aged 21 to 38 years (mean: 25.7). We compared their findings with a control group of 40 healthy adults-15 men and 25 women, aged 19 to 36 years (mean: 25.1). Allergen-specific IgE measurements were obtained with six groups of allergens: fungi, grass pollens, tree pollens, wild herbs, house dust mite 1, and house dust mite 2...
June 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28628552/a-case-study-of-high-velocity-persistent-geotropic-nystagmus-is-this-bppv
#18
Michael C Schubert, Pamela M Dunlap, Susan L Whitney
BACKGROUND AND PURPOSE: Deciphering the cause for a persistent, direction-changing geotropic nystagmus can be difficult. Migraine and light cupula are two possible causes, though can be confused with benign paroxysmal positional vertigo (BPPV) affecting the horizontal semicircular canal. In migraine, the persistent geotropic nystagmus tends to be slow; in light cupula, the nystagmus has been illustrated to beat in the direction opposite that of prone positioning. CASE DESCRIPTION: Here we describe a patient with initial occurrence then recurrence of a high velocity (≥30 deg/sec), persistent direction-changing geotropic nystagmus and vertigo with an intensity variable based on head position, which was difficult to manage...
July 2017: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/28624934/low-serum-diamine-oxidase-dao-activity-levels-in-patients-with-migraine
#19
Joan Izquierdo-Casas, Oriol Comas-Basté, M Luz Latorre-Moratalla, Marian Lorente-Gascón, Adriana Duelo, M Carmen Vidal-Carou, Luis Soler-Singla
Histamine intolerance is a disorder in the homeostasis of histamine due to a reduced intestinal degradation of this amine, mainly caused by a deficiency in the enzyme diamine oxidase (DAO). Among the several multi-faced symptoms associated with histamine intolerance, headache is one of the most recognized and disabling consequences. The aim of this study was to determine the prevalence of DAO deficiency in patients with a confirmed migraine diagnosis according to the current International Headache Society (IHS) and in non-migraine subjects...
June 17, 2017: Journal of Physiology and Biochemistry
https://www.readbyqxmd.com/read/28605629/analytic-information-processing-style-in-epilepsy-patients
#20
Marzia Buonfiglio, Francesco Di Sabato, Silvia Mandillo, Mariarita Albini, Carlo Di Bonaventura, Annateresa Giallonardo, Giuliano Avanzini
Relevant to the study of epileptogenesis is learning processing, given the pivotal role that neuroplasticity assumes in both mechanisms. Recently, evoked potential analyses showed a link between analytic cognitive style and altered neural excitability in both migraine and healthy subjects, regardless of cognitive impairment or psychological disorders. In this study we evaluated analytic/global and visual/auditory perceptual dimensions of cognitive style in patients with epilepsy. Twenty-five cryptogenic temporal lobe epilepsy (TLE) patients matched with 25 idiopathic generalized epilepsy (IGE) sufferers and 25 healthy volunteers were recruited and participated in three cognitive style tests: "Sternberg-Wagner Self-Assessment Inventory", the C...
June 9, 2017: Epilepsy & Behavior: E&B
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