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Urinary tract infection in children

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https://www.readbyqxmd.com/read/28438954/urinary-tract-infection-in-children
#1
Alexandra Hudson, Rodrigo L P Romao, Dawn MacLellan
No abstract text is available yet for this article.
April 24, 2017: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/28436231/the-utility-of-real-time-quantitative-polymerase-chain-reaction-genotype-detection-in-the-diagnosis-of-urinary-tract-infections-in-children
#2
Jon R Felt, Chelsey Yurkovich, Danielle M Garshott, Deepak Kamat, Ahmad Farooqi, Andrew M Fribley, Michael U Callaghan, Katherine Hebert
Urinary tract infections (UTIs) are the most common serious bacterial infection in children with significant morbidity with delayed diagnosis. Polymerase chain reaction (PCR) is very accurate in detecting bacteria and widely available, but has never been evaluated to detect UTIs in children. To assess the utility of PCR as a rapid diagnostic tool, we conducted a prospective cohort study of 193 urine samples from children younger than 36 months undergoing evaluation for UTI in the emergency department over a 10-month period...
April 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28434632/obesity-and-lower-urinary-tract-dysfunction-in-children-and-adolescents-further-research-into-new-relationships
#3
L G A Fraga, A Sampaio, N Boa-Sorte, M L Veiga, A A Nascimento Martinelli Braga, U Barroso
INTRODUCTION: Lower urinary tract dysfunction (LUTD) involves faults in the filling and emptying phases of bladder function in toilet-trained children with no previous infection or any other obvious pathology. Lower urinary tract dysfunction is associated with conditions such as vesicoureteral reflux, recurrent urinary infection, behavioral alterations and decreased quality of life. The literature suggests an association between LUTD and obesity; however, the association between each individual symptom and obesity has yet to be evaluated...
April 2, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28432830/prevalence-and-risk-factors-of-symptomatic-urinary-tract-infection-after-endoscopic-incision-for-the-treatment-of-ureterocele-in-children
#4
Kimihiko Moriya, Michiko Nakamura, Yoko Nishimura, Yukiko Kanno, Takeya Kitta, Masafumi Kon, Nobuo Shinohara
OBJECTIVE: To clarify the impact of endoscopic incision for ureterocele as an initial procedure, retrospective chart review was performed focusing on the prevalence and risk factors of symptomatic urinary tract infection after endoscopic incision. MATERIALS AND METHODS: Among children with ureterocele who were managed between September 1994 and April 2016, patients who were observed conservatively without additional surgical management after endoscopic incision were included in this study...
April 22, 2017: BJU International
https://www.readbyqxmd.com/read/28427379/novel-mutation-identified-in-severe-early-onset-tumor-necrosis-factor-receptor-associated-periodic-syndrome-a-case-report
#5
Suhas M Radhakrishna, Amy Grimm, Lori Broderick
BACKGROUND: Tumor Necrosis Factor Receptor-Associated Periodic Syndrome (TRAPS) is the second most common heritable autoinflammatory disease, typically presenting in pre-school aged children with fever episodes lasting 1-3 weeks. Systemic symptoms can include rash, myalgia, ocular inflammation, and serositis. CASE PRESENTATION: Here we report an unusual presentation of TRAPS in a 7 month old girl who presented with only persistent fever. She was initially diagnosed with incomplete Kawasaki Disease and received IVIG and infliximab; however, her fevers quickly recurred...
April 20, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28420322/epidemiology-of-paediatric-renal-stone-disease-a-22-year-single-centre-experience-in-the-uk
#6
Naomi Issler, Stephanie Dufek, Robert Kleta, Detlef Bockenhauer, Naima Smeulders, William Van't Hoff
BACKGROUND: Whilst still rare, the incidence of paediatric stone disease is increasing in developed countries and it is important to evaluate the aetiology. We set up a dedicated renal stone service for children combining medical and surgical expertise in 1993 and now have a large case series of children to investigate the epidemiology. METHODS: A retrospective hospital note review of children presenting with kidney stones during the last 22 years (1993-2015) was conducted...
April 18, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28420014/-febrile-urinary-tract-infections-when-are-they-an-emergency
#7
Evi Comploj, Armin Pycha
Urinary tract infections should be suspected in every febrile infant until proven otherwise. While older children and adolescents mostly present with classical features such as dysuria, flank pain and/or abdominal pain, secondary enuresis or pollakiuria, diagnosing infants or newborns, who are incapable of describing or pinpointing pain, can be much more challenging. As such, an infection with gradual and subtle onset may result in fulminant disease and emergency situations. In children with urinary tract infections and known mechanical or functional obstructions of the urinary tract, adequate drainage of the infected urinary tract may be necessary (e...
February 2017: Aktuelle Urologie
https://www.readbyqxmd.com/read/28413305/solitary-functioning-kidney-in-high-anorectal-malformation
#8
Kanishka Das, Srinivas Raju Rajkiran
AIM: A solitary functioning renal unit in high anorectal malformation may harbor anomalies in the upper/lower urinary tract that further compromise renal function and accelerate hyperfiltration injury. We aimed to analyze the clinical course, management, and outcome of children with a solitary renal unit and high anorectal malformation. MATERIALS AND METHODS: A cohort of solitary renal units in anorectal malformation managed between 2000 and 2015 with a defined protocol at a pediatric nephro-urology clinic are included in the study...
April 2017: Journal of Indian Association of Pediatric Surgeons
https://www.readbyqxmd.com/read/28412102/the-method-of-urine-sampling-is-not-a-valid-predictor-for-vesicoureteral-reflux-in-children-after-febrile-urinary-tract-infections
#9
Bernhard Haid, Judith Roesch, Christa Strasser, Josef Oswald
INTRODUCTION: The likelihood of detecting vesicoureteral reflux (VUR) after febrile urinary tract infections (UTI) in children logically should correlate with the correct diagnosis of the UTI. Beneath the unspecific symptoms of fever urine analysis is the main diagnostic criterion for the exact diagnosis of febrile UTIs in children. Use of inadequate urine sampling techniques during diagnosis may lead to impaired accuracy in UTI diagnosis. This could lead to the assumption that children, having diagnosed their UTI by the use of possibly inadequate urine sampling techniques should not be evaluated as consequently compared to those, where the diagnosis relied on sterile urine sampling techniques...
March 16, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28408336/hospital-acquired-urinary-tract-infections-in-neonatal-icu-patients-is-voiding-cystourethrogram-necessary
#10
Aeen M Asghar, Traci Leong, Christopher S Cooper, Angela M Arlen
OBJECTIVES: To evaluate the radiographic findings of neonatal intensive care unit (NICU) patients diagnosed with hospital-acquired urinary tract infection (UTI). METHODS: Children with no preexisting genitourinary anomalies undergoing a voiding cystourethrogram (VCUG) for culture-documented urinary tract infection (UTI) during NICU admission were identified. Demographics, microbiology results and imaging findings were evaluated. RESULTS: One hundred and forty-seven NICU patients underwent VCUG during the study period...
April 10, 2017: Urology
https://www.readbyqxmd.com/read/28407997/the-diagnosis-of-urinary-tract-infection-in-young-children-duty-study-clinical-rule-economic-evaluation
#11
MULTICENTER STUDY
William Hollingworth, John Busby, Christopher C Butler, Kathryn O'Brien, Jonathan A C Sterne, Kerenza Hood, Paul Little, Michael Lawton, Kate Birnie, Emma Thomas-Jones, Kim Harman, Alastair D Hay
OBJECTIVE: To estimate the cost-effectiveness of a two-step clinical rule using symptoms, signs and dipstick testing to guide the diagnosis and antibiotic treatment of urinary tract infection (UTI) in acutely unwell young children presenting to primary care. METHODS: Decision analytic model synthesising data from a multicentre, prospective cohort study (DUTY) and the wider literature to estimate the short-term and lifetime costs and healthcare outcomes (symptomatic days, recurrent UTI, quality adjusted life years) of eight diagnostic strategies...
April 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/28407828/-clinical-features-of-invasive-candidiasis-and-risk-factors-for-candida-bloodstream-infection-in-children-a-multicenter-study-in-urumqi-china
#12
Ai Bi Bai Ai Er Ken, Zhi-Hua Ma, Dai-Qin Xiong, Pei-Ru Xu
OBJECTIVE: To investigate the clinical features of invasive candidiasis in children and the risk factors for Candida bloodstream infection. METHODS: A retrospective study was performed on 134 children with invasive candidiasis and hospitalized in 5 tertiary hospitals in Urumqi, China, between January 2010 and December 2015. The Candida species distribution was investigated. The clinical data were compared between the patients with and without Candida bloodstream infection...
April 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28398936/endogenous-glucocorticoid-response-to-single-dose-dexamethasone-for-croup-in-children-a-pharmacodynamic-study
#13
Natasha Gill, Natalie Sirizzotti, David Johnson, Gary Joubert, Andrew S Kucey, Alvin Tieu, Brad L Urquhart, Melanie Columbus, Rodrick Lim, Michael Rieder, Shruti Mehrotra, Emily D Hartjes, Naveen Poonai
OBJECTIVES: Dexamethasone is associated with adrenal insufficiency in adults and children with chronic disease. This association has not been studied after single-dose oral dexamethasone, the standard of care for children with croup. We hypothesized that single-dose oral dexamethasone in children with croup is associated with a transient decrease in endogenous glucocorticoids. METHODS: We conducted a prospective, 2-arm, pharmacodynamic study of single-dose oral dexamethasone 0...
April 11, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28393507/-nephrectomies-in-poor-or-non-functioning-kidneys-is-it-the-right-thing-to-do
#14
B Estors, A E Hernández, E Calleja, M D Rodrigo, J Lumbreras, C Marhuenda
AIM OF THE STUDY: To review our management and outcomes of nephrectomies performed in patients with non-functioning kidneys. METHODS: Retrospective analysis of the patients who underwent nephrectomy surgery in our hospital between 2010 and 2014. Data was collected from the patient charts paying special attention to the clinical resolution of the symptoms that motivated surgery. MAIN RESULTS: A total of 18 nephrectomies were performed. Median age was of 6,5 years (range: 11 months to 15 years)...
July 10, 2016: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/28390079/pitfalls-of-diagnosing-urinary-tract-infection-in-infants-and-young-children
#15
Yasuhito Yamasaki, Osamu Uemura, Takuhito Nagai, Satoshi Yamakawa, Yoshiko Hibi, Masaki Yamamoto, Masaru Nakano, Katsuaki Kasahara, Zhang Bo
BACKGROUND: The objective of this study was to examine the sensitivity and specificity of pyuria-based diagnosis of urinary tract infection (UTI) in urine collected by transurethral catheterization, and the reliability of diagnosis of pyuria in urine collected in a perineal bag. The gold standard for UTI diagnosis was the presence of significant colony counts of a single organism in urine obtained in a sterile manner. METHODS: We enrolled 301 patients who underwent medical examination in our hospital for possible UTI between January 2005 and December 2009...
April 8, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28385450/predictors-of-upper-tract-damage-in-pediatric-neurogenic-bladder
#16
Raghu Prakash, Archana Puri, Rama Anand, Ajay K Jain, Brahmanand Lal, Vaibhav Garg
INTRODUCTION: Upper tract damage (UTD) is a life-threatening complication of neurogenic bladder (NB). Early identification of risk factors for UTD and institution of remedial measures may probably prevent UTD. The aim was to study the predictors of UTD in children 2 years or older with NB. METHOD: This cross-sectional, observational study over 2 years included 30 children. UTD was defined as serum creatinine of >1 mg/dL or society of fetal urology grade III-IV hydronephrosis or hydroureteronephrosis on ultrasonography or renal scars on (99)(m)technetium dimercaptosuccinic scan or subnormal glomerular filtration rate (GFR) for age...
March 22, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28371256/infectious-complications-in-children-with-acute-lymphoblastic-leukemia-treated-with-the-taiwan-pediatric-oncology-group-protocol-a-16-year-tertiary-single-institution-experience
#17
Meng-Ju Li, Hsiu-Hao Chang, Yung-Li Yang, Meng-Yao Lu, Pei-Lan Shao, Chun-Min Fu, An-Kuo Chou, Yen-Lin Liu, Kai-Hsin Lin, Li-Min Huang, Dong-Tsamn Lin, Shiann-Tarng Jou
BACKGROUND: Infection is a major complication in pediatric patients with acute lymphoblastic leukemia during chemotherapy. In this study, the infection characteristics were determined and risk factors analyzed based on the Taiwan Pediatric Oncology Group (TPOG) acute lymphoblastic leukemia (ALL) protocol. PROCEDURE: We retrospectively reviewed fever events during chemotherapy in 252 patients treated during two consecutive clinical trials at a single institution between 1997 and 2012...
April 1, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28371243/infection-rates-in-tacrolimus-versus-cyclosporine-treated-pediatric-kidney-transplant-recipients-on-a-rapid-discontinuation-of-prednisone-protocol-1-year-analysis
#18
Sarah J Kizilbash, Michelle N Rheault, Ananta Bangdiwala, Arthur Matas, Srinath Chinnakotla, Blanche M Chavers
AR is lower in pKTx recipients on Tac vs CsA. Data comparing infection outcomes for children treated with these agents are limited. We retrospectively studied infection outcomes in 96 pKTx recipients on a RDP. PS, DCGS, AR, and infection-free survival were assessed using Kaplan-Meier/log-rank tests and proportional hazards models. There were no differences in 1-year PS, DCGS, or AR between Tac and CsA recipients. After adjusting for AR, the hazard of CMV viremia was 4.0 times higher (95%CI: 1.04, 15.5; P = ...
March 31, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28370971/top-down-approach-is-possible-strategy-for-predicting-break-through-futis-and-renal-scars-in-infants
#19
Shina Kawai, Takahiro Kanai, Taiju Hyuga, Shigeru Nakamura, Jun Aoyagi, Takane Ito, Takashi Saito, Jun Odaka, Rieko Furukawa, Toshinori Aihara, Hideo Nakai
BACKGROUND: Several reports have mainly examined whether acute-phase technetium-99m dimercaptosuccinic acid (DMSA) scintigraphy can detect vesicoureteral reflux (VUR) and recommend acute-phase DMSA scintigraphy for initial imaging in children with febrile urinary tract infections (fUTIs). Recently, it has been emphasized the importance of identifying patients who have risks of recurrent fUTIs (r-fUTIs). To clarify the effectiveness of DMSA scintigraphy for predicting r-fUTIs in infants, we investigated the relationship between the defects on DMSA scintigraphy and r- fUTIs...
March 31, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28367708/urine-trem-1-as-a-marker-of-urinary-tract-infection-in-children
#20
Erick Sierra-Diaz, Alejandro Bravo Cuéllar, Pablo Cesar Ortiz Lazareno, Mariana García Gutiérrez, Hernandez Flores Georgina, Roberto Anaya Prado
Objective Triggering receptor expressed on myeloid cells (TREM)-1 is a receptor that is thought to improve recognition of patients with true infection. In this study, we investigated whether Triggering receptor expressed on myeloid cells (TREM-1) is present in urine samples from children with urinary tract infection (UTI) and in samples from healthy children. Methods A total of 128 samples met the inclusion criteria for the study. Urine samples were processed for culture and urinalysis as a regular protocol for patients with UTI...
January 1, 2017: Journal of International Medical Research
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