Emilio Pedrotti, Mattia Passilongo, Adriano Fasolo, Mario Nubile, Graziella Parisi, Rodolfo Mastropasqua, Sara Ficial, Marina Bertolin, Enzo Di Iorio, Diego Ponzin, Giorgio Marchini
PURPOSE: To correlate clinical, impression cytologic, and in vivo confocal microscopy findings on the corneal surface after cultured limbal stem cell transplantation. DESIGN: Prospective, interventional, noncomparative, masked case series. PARTICIPANTS: Thirteen patients with limbal stem cell deficiency after unilateral (9 eyes) or bilateral (2 eyes) chemical burn, liquid nitrogen injury (1 eye), or herpes simplex virus infection (1 eye). METHODS: Limbal cells were harvested from healthy or less affected eyes, cultured on 3T3 cells and fibrin glue, and transplanted to the patient's injured eye...
August 2015: Ophthalmology