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https://www.readbyqxmd.com/read/28588629/in-vitro-and-in-vivo-activity-of-artemisia-sieberi-against-trichomonas-gallinae
#1
M R Youssefi, M Abouhosseini Tabari, A A Moghadamnia
In Iranian folk medicine Artemisia sieberi has been used for treatment of parasite infections in human and animals. The present study was designed to evaluate the in vitro and in vivo effects of A. sieberi essential oil (EO) against Trichomonas gallinae. Trichomonas gallinae were recovered by wet mount method from infected native pigeons. The in vitro assays were accomplished in multi-well plates containing metronidazole (MTZ) as a standard antitrichomonal and EO in final concentrations of 2.5, 5, 10, 20, 50, and 100 μg/ml of culture medium containing 10(4) parasites...
2017: Iranian journal of veterinary research
https://www.readbyqxmd.com/read/28507464/chemical-composition-and-biological-activities-of-salvia-officinalis-essential-oil-from-tunisia
#2
Med Raâfet Ben Khedher, Saoussen Ben Khedher, Ikbal Chaieb, Slim Tounsi, Mohamed Hammami
The aim of this study is to evaluate the chemical composition, antioxidant, antimicrobial, insecticidal and allelopathic activities of Tunisia Salvia officinalis essential oil (SoEO). The SoEO was characterized by the presence of 49 components with camphor (25.14 %), α-thujone (18.83 %), 1,8-cineole (14.14 %), viridiflorol (7.98 %), β-thujone (4.46 %) and β-caryophyllene (3.30 %) as the major components, determined by gas chromatography-mass spectrometry. The level of antioxidant activity, determined by complementary tests, namely 2,2-diphenyl-1-picrylhydrazyl radical-scavenging (IC50= 6...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28488391/essential-oil-variability-in-natural-populations-of-artemisia-campestris-l-and-artemisia-herba-alba-asso-and-incidence-on-antiacetylcholinesterase-and-antioxidant-activities
#3
Faten Younsi, Sameh Mehdi, Oumayma Aissi, Najoua Rahali, Rym Jaouadi, Mohamed Boussaid, Chokri Messaoud
The intraspecific variability of Artemisia herba-alba and A. campestris essential oils and the evaluation of their antioxidant and antiacetylcholinesterase activities were determined. Artemisia herba-alba essential oil was found rich in camphor (19.61%), α-thujone (19.40%), β-thujone (9.44%), chrysanthenone (9.26%), and trans-sabinyl acetate (8.43%). The major compounds of A. campestris essential oil were germacrene D (16.38%), β-pinene (16.33%), and limonene (9.17%). Significant variation in the essential oil composition was observed among populations of each species...
May 10, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28477412/salvia-officinalis-l-essential-oils-from-spain-determination-of-composition-antioxidant-capacity-antienzymatic-and-antimicrobial-bioactivities
#4
Ana-Belen Cutillas, Alejandro Carrasco, Ramiro Martinez-Gutierrez, Virginia Tomas, Jose Tudela
Four essential oils (EOs) from Salvia officinalis L. cultivated in Spain (Murcia Province) were analyzed by gas chromatography coupled with mass spectrometry (GC/MS) to determine their relative and absolute compositions. The main components were α-thujone (22.8 - 41.7%), camphor (10.7 - 19.8%), 1,8-cineole (4.7 - 15.6%), and β-thujone (6.1 - 15.6%). Enantioselective gas chromatography identified (-)-α-thujone and (+)-camphor as the main enantiomers in all the analyzed EOs. Furthermore, when the EOs were tested to determine their antioxidant activity against free radicals and as ferric reducing and ferrous chelating agents, all were seen to have moderate activity due to the compounds they contained, such as linalool or terpinene...
May 6, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28472675/toxic-essential-oils-part-v-behaviour-modulating-and-toxic-properties-of-thujones-and-thujone-containing-essential-oils-of-salvia-officinalis-l-artemisia-absinthium-l-thuja-occidentalis-l-and-tanacetum-vulgare-l
#5
Niko S Radulović, Marija S Genčić, Nikola M Stojanović, Pavle J Randjelović, Zorica Z Stojanović-Radić, Nenad I Stojiljković
Neurotoxic thujones (α- and β-diastereoisomers) are common constituents of plant essential oils. In this study, we employed a statistical approach to determine the contribution of thujones to the overall observed behaviour-modulating and toxic effects of essential oils (Salvia officinalis L., Artemisia absinthium L., Thuja occidentalis L. and Tanacetum vulgare L.) containing these monoterpene ketones. The data from three in vivo neuropharmacological tests on rats (open field, light-dark, and diazepam-induced sleep), and toxicity assays (brine shrimp, and antimicrobial activity against a panel of microorganisms), together with the data from detailed chemical analyses, were subjected to a multivariate statistical treatment to reveal the possible correlation(s) between the content of essential-oil constituents and the observed effects...
May 1, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28395994/thujone-inhibits-the-function-of-%C3%AE-7-nicotinic-acetylcholine-receptors-and-impairs-nicotine-induced-memory-enhancement-in-one-trial-passive-avoidance-paradigm
#6
Ahmed Sultan, Keun-Hang Susan Yang, Dmitro Isaev, Eslam El Nebrisi, Nurulain Syed, Nadia Khan, Christopher F Howarth, Bassem Sadek, Murat Oz
Effects of thujone, a major ingredient of absinthe, wormwood oil and some herbal medicines, were tested on the function of α7 subunit of the human nicotinic acetylcholine (α7 nACh) receptor expressed in Xenopus oocytes using the two-electrode voltage-clamp technique. Thujone reversibly inhibited ACh (100μM)-induced currents with an IC50 value of 24.7μM. The effect of thujone was not dependent on the membrane potential and did not involve Ca(2+)-dependent Cl(-) channels expressed endogenously in oocytes...
June 1, 2017: Toxicology
https://www.readbyqxmd.com/read/28381767/volatile-components-of-the-essential-oil-of-artemisia-montana-and-their-sedative-effects
#7
Kento Kunihiro, Takao Myoda, Noriaki Tajima, Kotaro Gotoh, Tai Kaneshima, Takao Someya, Kazuki Toeda, Takane Fujimori, Makoto Nishizawa
The sedative effects of volatile components in the essential oil of Artemisia montana ("Yomogi") were investigated and measured using gas chromatography-mass spectrometry (GC-MS). Major components identified included 1,8-cineol, camphor, borneol, α-piperitone, and caryophyllene oxide. Among them, 1,8-cineol exhibited the highest flavor dilution (FD) value in an aroma extract dilution analysis (AEDA), followed by borneol, o-cymene, β-thujone, and bornyl acetate. The sedative effects of yomogi oil aroma were evaluated by sensory testing, analysis of salivary α-amylase activity, and measurement of relative fluctuation of oxygenated hemoglobin concentration in the brain using near-infrared spectroscopy (NIRS)...
April 4, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28378196/eco-friendly-control-of-the-poultry-red-mite-dermanyssus-gallinae-dermanyssidae-using-the-%C3%AE-thujone-rich-essential-oil-of-artemisia-sieberi-asteraceae-toxic-and-repellent-potential
#8
Mohaddeseh Abouhosseini Tabari, Mohammad Reza Youssefi, Giovanni Benelli
The poultry red mite, Dermanyssus gallinae, represents a key threat for the poultry industry worldwide. The control of D. gallinae is mainly achieved by continuous applications of acaricides. However, the fast-growing development of resistance, and the strict laws concerning chemicals admitted for treatments on food animals, highlighted the importance of alternative control tools. Here, we explored the potential of Artemisia sieberi essential oil against D. gallinae. In this study, the A. sieberi essential oil was analyzed using GC and GC-MS...
May 2017: Parasitology Research
https://www.readbyqxmd.com/read/28346993/artemisia-sieberi-besser-essential-oil-and-treatment-of-fungal-infections
#9
REVIEW
Mohaddese Mahboubi
A. sieberi essential oil has been used for treatment of hardly curable infectious ulcers in Middle East Medicine and has been famous due to its wormicide effects. In this review, we evaluated the potency of A. sieberi essential oil in treatment of fungal infections. We searched in PubMed Central, Science direct, Wiley, Springer, SID, and accessible books, reports, thesis. There is a lot of mixed information on chemical compositions of A. sieberi essential oil, but most articles reported α, β-thujones as the main components of essential oils...
May 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28314999/genetic-diversity-and-metabolic-profile-of-salvia-officinalis-populations-implications-for-advanced-breeding-strategies
#10
Eirini Sarrou, Ioannis Ganopoulos, Aliki Xanthopoulou, Domenico Masuero, Stefan Martens, Panagiotis Madesis, Athanasios Mavromatis, Paschalina Chatzopoulou
As a result of this work, we were able to characterize seven indigenous to Greece Salvia officinalis populations using genetic and metabolomic tools. These tools can be used to select the most promising genotypes, capable to design future breeding programs for high valuable varieties. An initial investigation was carried out to compare the genetic and metabolic diversity in S. officinalis grown in Greece and to discern the relationship between the two sets of data. Analysis of inter-simple sequence repeats (ISSR) revealed significant genetic differences among seven sage populations, which were grouped into three main clusters according to an UPGMA ISSR data-based dendrogram and Principle Coordinate Analysis...
August 2017: Planta
https://www.readbyqxmd.com/read/28276694/artemisia-umbelliformis-lam-and-g%C3%A3-n%C3%A3-pi-liqueur-volatile-profile-as-diagnostic-marker-for-geographic-origin-and-to-predict-liqueur-safety
#11
Lorenzo Boggia, Giuseppe Pignata, Barbara Sgorbini, Maria Laura Colombo, Arianna Marengo, Manuela Casale, Silvana Nicola, Carlo Bicchi, Patrizia Rubiolo
Artemisia umbelliformis, commonly known as "white génépi", is characterized by a volatile fraction rich in α- and β-thujones, two monoterpenoids; under European Union (EU) regulations these are limited to 35 mg/L in Artemisia-based beverages because of their recognized activity on the human central nervous system. This study reports the results of an investigation to define the geographical origin and thujone content of individual plants of A. umbelliformis from different geographical sites, cultivated experimentally at a single site, and to predict the thujone content in the resulting liqueurs through their volatile fraction...
April 5, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27976467/rapid-species-level-identification-of-salvias-by-chemometric-processing-of-ambient-ionisation-mass-spectrometry-derived-chemical-profiles
#12
Justine E Giffen, Ashton D Lesiak, A John Dane, Robert B Cody, Rabi A Musah
INTRODUCTION: The Salvia genus contains numerous economically important plants that have horticultural, culinary and nutraceutical uses. They are often similar in appearance, making species determination difficult. Species identification of dried Salvia products is also challenging since distinguishing plant morphological features are no longer present. OBJECTIVE: The development of a simple high-throughput method of analysis of fresh and dried Salvia leaves that would permit rapid species-level identification and detection of diagnostic biomarkers...
January 2017: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/27913788/safety-assessment-of-achillea-millefolium-as-used-in-cosmetics
#13
Lillian C Becker, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler, James G Marks, Ronald C Shank, Thomas J Slaga, Paul W Snyder, F Alan Andersen
Cosmetic ingredients derived from Achillea millefolium function in cosmetics as skin-conditioning agents-miscellaneous, skin-conditioning agents-humectants, and fragrance ingredients. The Cosmetic Ingredient Review Expert Panel (Panel) reviewed relevant animal and human data to determine their safety in cosmetics and raised concerns about cosmetics containing linalool, thujone, quercetin, hydroquinone, or α-peroxyachifolid. Because final product formulations may contain multiple botanicals, each containing similar constituents of concern, formulators are advised to be aware of these components and to avoid reaching levels that may be hazardous to consumers...
November 2016: International Journal of Toxicology
https://www.readbyqxmd.com/read/27879146/chemical-composition-and-antifungal-activity-of-essential-oils-from-medicinal-plants-of-kazakhstan
#14
Diego A Sampietro, Analía de Los A Gomez, Cristina M Jimenez, Emilio F Lizarraga, Zharkyn A Ibatayev, Yerlan M Suleimen, Cesar A Catalán
The composition of essential oils from leaves of Kazakhstan medicinal plants was analysed by GC-MS. The major compounds identified were 1,8-cineole (34.2%), myrcene (19.1%) and α-pinene (9.4%) in Ajania fruticulosa; 1,8-cineole (21.0%), β-thujone (11.0%), camphor (8.5%), borneol (7.3%) and α-thujone (6.5%), in Achillea nobilis; camphor (47.3%), 1,8-cineole (23.9%), camphene (9.8%) and β-thujone (6.0%) in Artemisia terrae-albae; 1,8-cineole(55.8%) and β-pinene (6.2%) in Hyssopus ambiguus; α-thuyene(46...
June 2017: Natural Product Research
https://www.readbyqxmd.com/read/27770682/activity-of-essential-oil-based-microemulsions-against-staphylococcus-aureus-biofilms-developed-on-stainless-steel-surface-in-different-culture-media-and-growth-conditions
#15
Campana Raffaella, Luca Casettari, Laura Fagioli, Marco Cespi, Giulia Bonacucina, Wally Baffone
Food safety is a fundamental concern for both consumers and the food industry, especially as the numbers of reported cases of food-associated infections continue to increase. Industrial surfaces can provide a suitable substrate for the development and persistence of bacterial organized in biofilms that represent a potential source of food contamination. The negative consumer perception of chemical disinfectants has shifted the attention to natural substances, such as plant extracts. The aim of this study was to investigate the possibility of using the essential oils (EOs) in the fight against S...
January 16, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/27770606/simultaneous-formulation-of-terbinafine-and-salvia-monoterpenes-into-chitosan-hydrogel-with-testing-biological-activity-of-corresponding-dialysates-against-c-albicans-yeast
#16
Alexandra Kodadová, Zuzana Vitková, Jarmila Oremusová, Petra Herdová, Anton Ťažký, Peter Mikuš
This work was aimed at a progressive formulation of drugs into chitosan hydrogels. It was taken into consideration that a therapeutic effect of the drugs could be enhanced by a combination of natural compounds with chemical (synthetic) drugs. In this work, sage essential oil (SEO) bicyclic monoterpenes with antiflogistic, antiseptic, and antimycotic properties were combined with terbinafine (TB) having a strong antimycotic activity. Detail optimization of the hydrogel-drugs composition (SEO monoterpenes, TB, chitosan, and polysorbate 80 concentrations), based on permeation experiment and UV absorption/GC-MS analysis of permeated species (eucalyptol, camphor, borneol, thujone, TB) in dialysates, was made...
January 1, 2017: Zeitschrift Für Naturforschung. C, A Journal of Biosciences
https://www.readbyqxmd.com/read/27709180/a-six-step-total-synthesis-of-%C3%AE-thujone-and-d6-%C3%AE-thujone-enabling-facile-access-to-isotopically-labelled-metabolites
#17
Irene Thamm, Johannes Richers, Michael Rychlik, Konrad Tiefenbacher
The short synthesis of α-thujone relies on the functionalization of the readily available dimethylfulvene. Furthermore, the three main metabolites of the natural product were also synthesized. Since d6-acetone can be used as a starting material, the route developed allows for the facile incorporation of isotopic labels which are required for detecting and quantifying trace amounts via GC/MS analysis.
September 22, 2016: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/27525992/chemotypic-variation-in-volatiles-and-herbivory-for-sagebrush
#18
Richard Karban, Patrick Grof-Tisza, James D Blande
Plants that are damaged by herbivores emit complex blends of volatile compounds that often cause neighboring branches to induce resistance. Experimentally clipped sagebrush foliage emits volatiles that neighboring individuals recognize and respond to. These volatiles vary among individuals within a population. Two distinct types are most common with either thujone or camphor as the predominate compound, along with other less common types. Individuals respond more effectively to cues from the same type, suggesting that some of the informative message is contained in the compounds that differentiate the types...
August 2016: Journal of Chemical Ecology
https://www.readbyqxmd.com/read/27451252/a-new-chemical-tool-for-absinthe-producers-quantification-of-%C3%AE-%C3%AE-thujone-and-the-bitter-components-in-artemisia-absinthium
#19
Benoit Bach, Marilyn Cleroux, Mayra Saillen, Patrik Schönenberger, Stephane Burgos, Julien Ducruet, Armelle Vallat
The concentrations of α/β-thujone and the bitter components of Artemisia absinthium were quantified from alcoholic wormwood extracts during four phenological stages of their harvest period. A solid-phase micro-extraction method coupled to gas chromatography-mass spectrometry was used to determine the concentration of the two isomeric forms of thujone. In parallel, the combination of ultra-high pressure liquid chromatography and high resolution mass spectrometry allowed to quantify the compounds absinthin, artemisetin and dihydro-epi-deoxyarteannuin B...
December 15, 2016: Food Chemistry
https://www.readbyqxmd.com/read/27447740/artemisia%C3%A2-arborescens-essential-oil-composition-enantiomeric-distribution-and-antimicrobial-activity-from-different-wild-populations-from-the-mediterranean-area
#20
Mohammed El-Amin Said, Marcello Militello, Sergio Saia, Luca Settanni, Aurora Aleo, Caterina Mammina, Isabelle Bombarda, Pierre Vanloot, Christian Roussel, Nathalie Dupuy
Aerial parts of Artemisia arborescens were collected from different sites of the Mediterranean area (southwestern Algeria and southern Italy) and the chemical composition of their essential oil (EO) extracted by hydrodistillation was studied by both gas chromatography (GC) equipped with an enantioselective capillary column and GC/mass spectrometry (GC/MS). The EOs obtained were tested against several Listeria monocytogenes strains. Using GC and GC/MS, 41 compounds were identified, accounting for 96.0 - 98...
August 2016: Chemistry & Biodiversity
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