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Mercury toxicity

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https://www.readbyqxmd.com/read/28209268/inorganic-mercury-prevents-the-differentiation-of-sh-sy5y-cells-amyloid-precursor-protein-microtubule-associated-proteins-and-ros-as-potential-targets
#1
Miguel Chin Chan, Elizabeth Bautista, Isabel Alvarado-Cruz, Betzabet Quintanilla-Vega, José Segovia
Exposure to mercury (Hg) occurs through different pathways and forms including methylmecury (MeHg) from seafood and rice, ethylmercury (EtHg), and elemental Hg (Hg(0)) from dental amalgams and artisanal gold mining. Once in the brain all these forms are transformed to inorganic Hg (I-Hg), where it bioaccumulates and remains for long periods. Hg is a well-known neurotoxicant, with its most damaging effects reported during brain development, when cellular key events, such as cell differentiation take place. A considerable number of studies report an impairment of neuronal differentiation due to MeHg exposure, however the effects of I-Hg, an important form of Hg found in brain, have received less attention...
February 6, 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/28208276/single-drop-solution-electrode-discharge-induced-cold-vapor-generation-coupling-to-matrix-solid-phase-dispersion-a-robust-approach-for-sensitive-quantification-of-total-mercury-distribution-in-fish
#2
Qian Chen, Yao Lin, Yunfei Tian, Li Wu, Lu Yang, Xiandeng Hou, Chengbin Zheng
Sensitive quantification of mercury distribution in fish is challenging because of insufficient sensitivities of conventional analytical methods, the limited mass of organs (tens of micrograms to several milligrams), and dilution of analyte concentration from sample digestion. In this work, a simple and robust approach coupling multiwall carbon nanotubes assisted matrix solid-phase dispersion (MWCNTs-MSPD) to single-drop solution electrode glow discharge-induced cold vapor generation (SD-SEGD-CVG) was developed for the sensitive determination of mercury in limited amount of sample...
February 7, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28205137/erratum-to-effect-of-probiotic-bacillus-coagulans-and-lactobacillus-plantarum-on-alleviation-of-mercury-toxicity-in-rat
#3
Majid Majlesi, Seyed Shahram Shekarforoush, Hamid Reza Ghaisari, Saeid Nazifi, Javad Sajedianfard, Mohammad Hadi Eskandari
No abstract text is available yet for this article.
February 15, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/28190573/stable-sulfur-isotopes-identify-habitat-specific-foraging-and-mercury-exposure-in-a-highly-mobile-fish-community
#4
Meghan K Carr, Timothy D Jardine, Lorne E Doig, Paul D Jones, Lalita Bharadwaj, Brett Tendler, John Chételat, Pete Cott, Karl-Erich Lindenschmidt
Tracking the uptake and transfer of toxic chemicals, such as mercury (Hg), in aquatic systems is challenging when many top predators are highly mobile and may therefore be exposed to chemicals in areas other than their location of capture, confounding interpretation of bioaccumulation trends. Here we show how the application of a less commonly used ecological tracer, stable sulfur isotope ratios ((34)S/(32)S, or δ(34)S), in a large river-delta-lake complex in northern Canada allows differentiation of resident from migrant fishes, beyond what was possible with more conventional (13)C/(12)C and (15)N/(14)N measurements...
February 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28185733/evaluating-the-potential-health-risk-of-toxic-trace-elements-in-vegetables-accounting-for-variations-in-soil-factors
#5
Yang Yang, Weiping Chen, Meie Wang, Yanling Li, Chi Peng
Vegetable crop consumption is one of the main sources of dietary exposure to toxic trace elements (TEs). A paired survey of soil and vegetable samples was conducted in 589 agricultural sites in the Youxian prefecture, southern China, to investigate the effect of soil factors on the accumulation of arsenic, cadmium, mercury, and lead in different vegetables. A site-specific model was developed to estimate the health risk from vegetable consumption. The TE concentration varied in different plant species, and rape can be cultivated in contaminated areas for its potential use in restricting the transfer of TE from soil to edible plant parts...
February 6, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28183061/trace-elements-in-oceanic-pelagic-communities-in-the-western-indian-ocean
#6
Nathalie Bodin, Dora Lesperance, Rona Albert, Stephanie Hollanda, Philippe Michaud, Maxime Degroote, Carine Churlaud, Paco Bustamante
The mineral composition of target and non-target pelagic fish caught by purse-seiners and longliners in the western-central Indian Ocean was determined. From the 10 essential elements analysed, selenium and zinc showed the highest concentrations in swordfish and blue marlin while Indian mackerel appeared as a good source of copper, iron and chrome. All catch had levels of lead and cadmium, two toxic elements, below the maximum sanitary limits. Although some concerns were raised regarding mercury concentrations in the largest species (wahoo, swordfish and blue marlin), molar ratios of mercury and selenium indicate that all oceanic pelagic fish from the western-central Indian Ocean are safe for human consumption...
January 21, 2017: Chemosphere
https://www.readbyqxmd.com/read/28178594/the-effects-of-fluoride-based-fire-fighting-foams-on-soil-microbiota-activity-and-plant-growth-during-natural-attenuation-of-perfluorinated-compounds
#7
Renato Nallin Montagnolli, Paulo Renato Matos Lopes, Jaqueline Matos Cruz, Elis Marina Turini Claro, Gabriela Mercuri Quiterio, Ederio Dino Bidoia
The use of fluoride based foams increases the effectiveness of fire-fighting operations, but they are also accompanied by major drawbacks regarding environmental safety of perfluorinated compounds (PFCs). The main concern with PFCs release is due to their well-known persistence and bioaccumulative potential, as they have been detected in many environmental samples. There is a significant knowledge gap on PFC toxicity to plants, even though such data could be useful towards bioremediation procedures. It is consensus that a realistic assessment of fire-fighting foam toxicity should cover as many test organisms as possible, however, few studies combine the performance of ecotoxicological tests with a detailed study of microbial communities in soil contaminated with firefighting foams...
January 30, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28164814/environmental-justice-and-underserved-communities
#8
REVIEW
Vincent Morelli, Carol Ziegler, Omotayo Fawibe
Underserved communities suffer from environmental inequities. Gases lead to hypoxia and respiratory compromise, ozone to increased respiratory illnesses and decreased mental acuity, and mercury to prenatal cognitive disabilities and antisocial behaviors. Lead toxicity is associated with developmental delays. Cadmium is linked with cancer. The smaller sizes of air pollution particulate matter are pathogenic and are associated with cardiovascular and pulmonary disease and nervous system disorders. Bisphenol A is being studied for possible links to cancer and pregnancy risks...
March 2017: Primary Care
https://www.readbyqxmd.com/read/28157152/toward-an-assessment-of-the-global-inventory-of-present-day-mercury-releases-to-freshwater-environments
#9
David Kocman, Simon J Wilson, Helen M Amos, Kevin H Telmer, Frits Steenhuisen, Elsie M Sunderland, Robert P Mason, Peter Outridge, Milena Horvat
Aquatic ecosystems are an essential component of the biogeochemical cycle of mercury (Hg), as inorganic Hg can be converted to toxic methylmercury (MeHg) in these environments and reemissions of elemental Hg rival anthropogenic Hg releases on a global scale. Quantification of effluent Hg releases to aquatic systems globally has focused on discharges to the global oceans, rather than contributions to freshwater systems that affect local exposures and risks associated with MeHg. Here we produce a first-estimate of sector-specific, spatially resolved global aquatic Hg discharges to freshwater systems...
February 1, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28146278/detection-and-manipulation-of-the-stress-response-protein-metallothionein
#10
Sadikshya Bhandari, Clare Melchiorre, Kristen Dostie, Debby Laukens, Lindsey Devisscher, Ariel Louwrier, Amy Thees, Michael A Lynes
Metallothioneins (MTs) are small molecular weight stress response proteins that play a central role as reservoir of essential divalent heavy metal cations such as zinc and copper, and also can diminish the effects of toxic heavy metals such as mercury and cadmium. Historically, MT has been considered to be an intracellular protein with roles to play in the management of heavy metals, as a regulator of cellular redox potential, and as a buffer of free radicals. Our recent studies have highlighted immunomodulatory role of MT in inflammatory diseases and also in the progression of metastatic cell movement...
February 1, 2017: Current Protocols in Toxicology
https://www.readbyqxmd.com/read/28139322/the-local-impact-of-a-coal-fired-power-plant-on-inorganic-mercury-and-methyl-mercury-distribution-in-rice-oryza-sativa-l
#11
Xiaohang Xu, Bo Meng, Chao Zhang, Xinbin Feng, Chunhao Gu, Jianyang Guo, Kevin Bishop, Zhidong Xu, Sensen Zhang, Guangle Qiu
Emission from coal-fired power plants is one of the major anthropogenic sources of mercury (Hg) in the environment, because emitted Hg can be quickly deposited nearby the source, attention is paid to the effects of coal-burning facilities on levels of toxic methyl-mercury (MeHg) in biota near such sources. Since rice is an agricultural crop that can bio-accumulate MeHg, the potential effects of a large Hg-emitting coal-fired power plant in Hunan Province, China on both inorganic Hg (Hg(II)) and MeHg distributions in rice was investigated...
January 27, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28121142/stable-covalent-organic-frameworks-for-exceptional-mercury-removal-from-aqueous-solutions
#12
Ning Huang, Lipeng Zhai, Hong Xu, Donglin Jiang
The pre-designable porous structures found in covalent organic frameworks (COFs) render them attractive as a molecular platform for addressing environmental issues such as removal of toxic heavy metal ions from water. However, a rational structural design of COFs in this aspect has not been explored. Here we report the rational design of stable COFs for Hg(II) removal through elaborate structural design and control over skeleton, pore size, and pore walls. The resulting framework is stable under strong acid and base conditions, possesses high surface area, has large mesopores, and contains dense sulfide functional termini on the pore walls...
February 7, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28118383/methylmercury-causes-blood-brain-barrier-damage-in-rats-via-upregulation-of-vascular-endothelial-growth-factor-expression
#13
Tetsuya Takahashi, Masatake Fujimura, Misaki Koyama, Masato Kanazawa, Fusako Usuki, Masatoyo Nishizawa, Takayoshi Shimohata
Clinical manifestations of methylmercury (MeHg) intoxication include cerebellar ataxia, concentric constriction of visual fields, and sensory and auditory disturbances. The symptoms depend on the site of MeHg damage, such as the cerebellum and occipital lobes. However, the underlying mechanism of MeHg-induced tissue vulnerability remains to be elucidated. In the present study, we used a rat model of subacute MeHg intoxication to investigate possible MeHg-induced blood-brain barrier (BBB) damage. The model was established by exposing the rats to 20-ppm MeHg for up to 4 weeks; the rats exhibited severe cerebellar pathological changes, although there were no significant differences in mercury content among the different brain regions...
2017: PloS One
https://www.readbyqxmd.com/read/28115105/highly-selective-and-quantitative-colorimetric-detection-of-mercury-ii-ions-by-carrageenan-functionalized-ag-agcl-nanoparticles
#14
Kannan Badri Narayanan, Sung Soo Han
The natural algal polysaccharide carrageenan was used for the greener synthesis of silver/silver chloride nanoparticles (Carr-Ag/AgCl NPs) without any toxic chemicals. We report the robust, highly selective, and sensitive colorimetric sensing of Hg(2+) ions using Carr-Ag/AgCl NPs without any further surface modification. The dark-brown color of a solution of Carr-Ag/AgCl NPs turned to white in a concentration-dependent manner with the addition of Hg(2+) ions, confirming the interaction of Carr-Ag/AgCl NPs with Hg(2+) ions...
March 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28112087/tackling-the-climate-targets-set-by-the-paris-agreement-cop-21-green-leadership-empowers-public-hospitals-to-overcome-obstacles-and-challenges-in-a-resource-constrained-environment
#15
E Weimann, B Patel
The healthcare sector itself contributes to climate change, the creation of hazardous waste, use of toxic metals such as mercury, and water and air pollution. To mitigate the effect of healthcare provision on the deteriorating environment and avoid creating further challenges for already burdened health systems, Global Green Hospitals was formed as a global network. Groote Schuur Hospital (GSH), as the leading academic hospital in Africa, joined the network in 2014. Since then, several projects have been initiated to reduce the amount of general waste, energy consumption and food waste, and create an environmentally friendlier and more sustainable hospital in a resource-constrained public healthcare setting...
December 21, 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28111002/more-surprises-in-the-global-greenhouse-human-health-impacts-from-recent-toxic-marine-aerosol-formations-due-to-centennial-alterations-of-world-wide-coastal-food-webs
#16
REVIEW
J J Walsh, J M Lenes, R H Weisberg, L Zheng, C Hu, K A Fanning, R Snyder, J Smith
Reductions of zooplankton biomasses and grazing pressures were observed during overfishing-induced trophic cascades and concurrent oil spills at global scales. Recent phytoplankton increments followed, once Fe-, P-, and N-nutrient limitations of commensal diazotrophs and dinoflagellates were also eliminated by respective human desertification, deforestation, and eutrophication during climate changes. Si-limitation of diatoms instead ensued during these last anthropogenic perturbations of agricultural effluents and sewage loadings...
January 19, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28110358/pollution-assessment-of-the-biob%C3%A3-o-river-chile-prioritization-of-substances-of-concern-under-an-ecotoxicological-approach
#17
Álvaro Alonso, Ricardo Figueroa, Pilar Castro-Díez
The water demand for human activities is rapidly increasing in developing countries. Under these circumstances, preserving aquatic ecosystems should be a priority which requires the development of quality criteria. In this study we perform a preliminary prioritization of the risky substances based on reported ecotoxicological studies and guidelines for the Biobío watershed (Central Chile). Our specific aims are (1) reviewing the scientific information on the aquatic pollution of this watershed, (2) determining the presence and concentration of potential toxic substances in water, sediment and effluents, (3) searching for quality criteria developed by other countries for the selected substances and (4) prioritizing the most risky substances by means of deterministic ecotoxicological risk assessment...
January 21, 2017: Environmental Management
https://www.readbyqxmd.com/read/28110010/dietary-exposure-to-toxic-and-essential-trace-elements-by-consumption-of-wild-and-farmed-carp-cyprinus-carpio-and-caspian-kutum-rutilus-frisii-kutum-in-iran
#18
Ali Heshmati, Javad Karami-Momtaz, Amir Nili-Ahmadabadi, Sabah Ghadimi
This study was conducted to determine and compare the concentrations of mercury (Hg), cadmium (Cd), arsenic (As), lead (Pb), nickel (Ni), iron (Fe), zinc (Zn), copper (Cu), manganese (Mn), cobalt (Co), and selenium (Se) in the muscle of wild and farmed carp (Cyprinus carpio) and wild and farmed Caspian kutum (Rutilus frisii kutum) collected from south-western Caspian Sea areas of Iran between December 2014 and March 2015. In addition, risk assessment of consumers to exposure to metals through fish consumption was estimated...
January 5, 2017: Chemosphere
https://www.readbyqxmd.com/read/28108889/hg-and-se-exposure-in-brain-tissues-of-striped-dolphin-stenella-coeruleoalba-and-bottlenose-dolphin-tursiops-truncatus-from-the-tyrrhenian-and-adriatic-seas
#19
Antonio Bellante, Fabio D'Agostino, Anna Traina, Daniela Piazzese, Maria Francesca Milazzo, Mario Sprovieri
In this study we analyzed Hg and Se concentrations in dolphin brain tissues of fifteen specimens of striped dolphin (Stenella coeruleoalba) and eight specimens of bottlenose dolphin (Tursiops truncatus) stranded in the Tyrrhenian and Adriatic Seas, in order to assess the toxicological risks associated with Hg exposure. High Hg concentrations were found in brain tissues of both analyzed specie (1.86-243 mg/kg dw for striped dolphin and 2.1-98.7 mg/kg dw for bottlenose dolphin), exceeding levels associated with marine mammals neurotoxicity...
January 21, 2017: Ecotoxicology
https://www.readbyqxmd.com/read/28106810/genetic-aspects-of-susceptibility-to-mercury-toxicity-an-overview
#20
REVIEW
Virginia Andreoli, Francesca Sprovieri
Human exposure to mercury is still a major public health concern. In this context, children have a higher susceptibility to adverse neurological mercury effects, compared to adults with similar exposures. Moreover, there exists a marked variability of personal response to detrimental mercury action, in particular among population groups with significant mercury exposure. New scientific evidence on genetic backgrounds has raised the issue of whether candidate susceptibility genes can make certain individuals more or less vulnerable to mercury toxicity...
January 18, 2017: International Journal of Environmental Research and Public Health
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