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Mercury toxicity

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https://www.readbyqxmd.com/read/28645012/associations-between-toxic-and-essential-trace-elements-in-maternal-blood-and-fetal-congenital-heart-defects
#1
Yanqiu Ou, Michael S Bloom, Zhiqiang Nie, Fengzhen Han, Jinzhuang Mai, Jimei Chen, Shao Lin, Xiaoqing Liu, Jian Zhuang
Prenatal exposure to toxic trace elements, including heavy metals, is an important public health concern. Few studies have assessed if individual and multiple trace elements simultaneously affect cardiac development. The current study evaluated the association between maternal blood lead (Pb), cadmium (Cd), chromium (Cr), copper (Cu), mercury (Hg), and selenium (Se) levels and congenital heart defects (CHDs) in offspring. This hospital-based case-control study included 112 case and 107 control infants. Maternal peripheral blood draw was made during gestational weeks 17-40 and used to determine trace element levels by inductively coupled plasma mass spectrometry...
June 20, 2017: Environment International
https://www.readbyqxmd.com/read/28643849/prevalence-of-exposure-of-heavy-metals-and-their-impact-on-health-consequences
#2
Kanwal Rehman, Fiza Fatima, Iqra Waheed, Muhammad Sajid Hamid Akash
Even in the current era of growing technology, the concentration of heavy metals present in drinking water is still not within the recommended limits as set by the regulatory authorities in different countries of the world. Drinking water contaminated with heavy metals namely; arsenic, cadmium, nickel, chromium, mercury, chromium, zinc and lead is becoming a major health concern for public and health care professionals. Occupational exposure to heavy metals is known to occur by the utilization of these metals in various industrial processes and/or contents including color pigments and alloys...
June 23, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28641884/oxidative-stress-profiles-in-brain-point-out-a-higher-susceptibility-of-fish-to-waterborne-divalent-mercury-compared-to-dietary-organic-mercury
#3
Olívia Cardoso, Sónia Puga, Fátima Brandão, João Canário, Nelson J O'Driscoll, Maria Ana Santos, Mário Pacheco, Patrícia Pereira
This study examines, for the first time, the neurotoxicity of Hg(II) and MeHg in fish (Diplodus sargus) in a time-course comparative perspective and considering realistic exposure levels and routes. Both forms followed an identical time-variation pattern of accumulation in the brain, but dietary MeHg was more efficiently transported to the brain. MeHg was substantially eliminated from the brain in 28days of depuration, which did not occur for Hg(II). Moreover, Hg(II) displayed a high neurotoxicity potential, as unveiled by the poor activation of brain antioxidant defenses and recurrent oxidative damage (as protein oxidation), while the opposite was recorded upon MeHg exposure...
June 19, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28622806/graphitic-carbon-nitride-supported-platinum-nanocomposites-for-rapid-and-sensitive-colorimetric-detection-of-mercury-ions
#4
Yi-Wei Wang, Lixing Wang, Fengping An, Hui Xu, Zejin Yin, Shurong Tang, Huang-Hao Yang, Hongbo Song
In this study, graphitic carbon nitride supported platinum nanocomposites (g-C3N4/PtNPs) have been synthesized for the first time by an ultrasonic-assisted chemical reduction method. By using g-C3N4 as the stabilizer, Pt ions could be reduced to PtNPs by NaBH4 and uniformly deposited on the surface of g-C3N4. The resulting g-C3N4/PtNPs exhibited enhanced catalytic activity for the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) compared to that of g-C3N4 or PtNPs alone. After interaction with Hg(2+), the catalytic activity of g-C3N4/PtNPs was effectively inhibited due to the formation of HgPt amalgam...
August 8, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28620728/contents-of-heavy-metals-in-chinese-edible-herbs-evidence-from-a-case-study-of-epimedii-folium
#5
Xiao-Hua Yang, Hua-Feng Zhang, Li-Li Niu, Ying Wang, Jiang-Hua Lai
Toxic heavy metal contamination in Chinese edible herbs has raised a worldwide concern. In this study, heavy metals in Epimedii Folium, an edible medicinal plant in China, were quantitatively analyzed. Variations of heavy metals in different species, in various organs (i.e., leaves, stems, and roots), in wild-growing and cultivated plants, and in 35 market samples of Epimedii Folium, were systematically investigated. In all of Epimedium samples, Hg (mercury) was not detectable (0.00 μg/g). Four species, Epimedium pubescens, Epimedium sagittatum, Epimedium brevicornu, and Epimedium wushanense, were found to contain Cu (copper) and Pb (lead)...
June 16, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28614596/efficient-mercury-capture-using-functionalized-porous-organic-polymer
#6
Briana Aguila, Qi Sun, Jason A Perman, Lyndsey D Earl, Carter W Abney, Radwan Elzein, Rudy Schlaf, Shengqian Ma
The primary challenge in materials design and synthesis is achieving the balance between performance and economy for real-world application. This issue is addressed by creating a thiol functionalized porous organic polymer (POP) using simple free radical polymerization techniques to prepare a cost-effective material with a high density of chelating sites designed for mercury capture and therefore environmental remediation. The resulting POP is able to remove aqueous and airborne mercury with uptake capacities of 1216 and 630 mg g(-1) , respectively...
June 14, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28600984/impaired-cross-talk-between-the-thioredoxin-and-glutathione-systems-is-related-to-ask-1-mediated-apoptosis-in-neuronal-cells-exposed-to-mercury
#7
Vasco Branco, Lucia Coppo, Susana Solá, Jun Lu, Cecília M P Rodrigues, Arne Holmgren, Cristina Carvalho
Mercury (Hg) compounds target both cysteine (Cys) and selenocysteine (Sec) residues in peptides and proteins. Thus, the components of the two major cellular antioxidant systems - glutathione (GSH) and thioredoxin (Trx) systems - are likely targets for mercurials. Hg exposure results in GSH depletion and Trx and thioredoxin reductase (TrxR) are prime targets for mercury. These systems have a wide-range of common functions and interaction between their components has been reported. However, toxic effects over both systems are normally treated as isolated events...
June 1, 2017: Redox Biology
https://www.readbyqxmd.com/read/28599206/mercury-flow-through-an-asian-rice-based-food-web
#8
Kasun S Abeysinghe, Guangle Qiu, Eben Goodale, Christopher W N Anderson, Kevin Bishop, David C Evers, Morgan W Goodale, Holger Hintelmann, Shengjie Liu, Christos Mammides, Rui-Chang Quan, Jin Wang, Pianpian Wu, Xiao-Hang Xu, Xiao-Dong Yang, Xinbin Feng
Mercury (Hg) is a globally-distributed pollutant, toxic to humans and animals. Emissions are particularly high in Asia, and the source of exposure for humans there may also be different from other regions, including rice as well as fish consumption, particularly in contaminated areas. Yet the threats Asian wildlife face in rice-based ecosystems are as yet unclear. We sought to understand how Hg flows through rice-based food webs in historic mining and non-mining regions of Guizhou, China. We measured total Hg (THg) and methylmercury (MeHg) in soil, rice, 38 animal species (27 for MeHg) spanning multiple trophic levels, and examined the relationship between stable isotopes and Hg concentrations...
June 6, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28597086/influence-of-a-former-mining-area-in-the-heavy-metals-concentrations-in-blood-of-free-living-mediterranean-pond-turtles-mauremys-leprosa
#9
E Martínez-López, P Gómez-Ramírez, S Espín, M P Aldeguer, A J García-Fernández
The objective of this study was to assess metal exposure in the Mediterranean Pond Turtle (Mauremys leprosa) inhabiting a watercourse in an ancient mining district polluted by different metals ("Rambla de Las Moreras", southeastern Spain) and included in the Ramsar Convention. For this purpose, mercury (Hg), lead (Pb), copper (Cu), zinc (Zn) and cadmium (Cd) were analysed in blood samples from 42 M. leprosa healthy adults (27 males and 13 females). The highest median concentrations were found for Zn, followed by Cu, Pb, Hg and Cd (366, 33, 9, 0...
June 9, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28595786/increased-risk-for-an-atypical-autism-diagnosis-following-thimerosal-containing-vaccine-exposure-in-the-united-states-a-prospective-longitudinal-case-control-study-in-the-vaccine-safety-datalink
#10
David A Geier, Janet K Kern, Mark R Geier
BACKGROUND: Thimerosal is an organic-mercury (Hg)-containing compound (49.55% Hg by weight) historically added to many multi-dose vials of vaccine as a preservative and still added to some vaccines today. Concerns about the toxic effects from Thimerosal-containing childhood vaccines and the risk of an atypical autism diagnosis were evaluated in this study. METHODS: A hypothesis-testing, prospective longitudinal, case-control study assessed exposure to Hg from Thimerosal-containing hepatitis B vaccines (TM-HepB) among cases diagnosed with atypical autism (n=164) and controls (n=15,216)...
July 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/28588813/severe-dermatitis-might-be-caused-by-a-cross-reaction-between-nickel-and-palladium-and-dental-amalgam-resolved-following-removal-of-dental-restorations
#11
Yoshiro Fujii
This report demonstrates a case of atopic dermatitis that was unresponsive to topical steroid therapy. This clinical report highlights the fact that metals used in dental treatment, such as mercury, as well as cross-reactions between nickel and palladium, may cause systemic hypersensitivity or toxicity.
June 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28582722/adsorption-of-mercury-ions-from-wastewater-by-a-hyperbranched-and-multi-functionalized-dendrimer-modified-mixed-oxides-nanoparticles
#12
M Arshadi, F Mousavinia, A Khalafi-Nezhad, H Firouzabadi, A Abbaspourrad
In this paper, a novel heterogeneous nanodendrimer with generation of G2.0 was prepared by individual grafting of diethylenetriamine, triazine and l-cysteine methyl ester on the modified aluminum-silicate mixed oxides as a potent adsorbent of Hg(II) ions from aqueous media. The prepared nanodendrimer was characterized by nuclear magnetic resonance spectrum ((1)H NMR and (13)C NMR), Fourier transform infrared spectroscopy (FT-IR), Diffuse reflectance UV-Vis spectroscopy (DR UV-Vis), zeta potential (ζ), inductively coupled plasma atomic emission spectroscopy (ICP-AES), transmission electron microscopy (TEM), scanning electron microscopy (SEM), nitrogen adsorption experiments at -196°C and elemental analysis...
May 19, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28580426/methylmercury-uptake-and-degradation-by-methanotrophs
#13
Xia Lu, Wenyu Gu, Linduo Zhao, Muhammad Farhan Ul Haque, Alan A DiSpirito, Jeremy D Semrau, Baohua Gu
Methylmercury (CH3Hg(+)) is a potent neurotoxin produced by certain anaerobic microorganisms in natural environments. Although numerous studies have characterized the basis of mercury (Hg) methylation, no studies have examined CH3Hg(+) degradation by methanotrophs, despite their ubiquitous presence in the environment. We report that some methanotrophs, such as Methylosinus trichosporium OB3b, can take up and degrade CH3Hg(+) rapidly, whereas others, such as Methylococcus capsulatus Bath, can take up but not degrade CH3Hg(+)...
May 2017: Science Advances
https://www.readbyqxmd.com/read/28577385/mercury-levels-of-yellowfin-tuna-thunnus-albacares-are-associated-with-capture-location
#14
Sascha C T Nicklisch, Lindsay T Bonito, Stuart Sandin, Amro Hamdoun
Mercury is a toxic compound to which humans are exposed by consumption of fish. Current fish consumption advisories focus on minimizing the risk posed by the species that are most likely to have high levels of mercury. Less accounted for is the variation within species, and the potential role of the geographic origin of a fish in determining its mercury level. Here we surveyed the mercury levels in 117 yellowfin tuna caught from 12 different locations worldwide. Our results indicated significant variation in yellowfin tuna methylmercury load, with levels that ranged from 0...
May 31, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28570991/from-antarctica-to-the-subtropics-contrasted-geographical-concentrations-of-selenium-mercury-and-persistent-organic-pollutants-in-skua-chicks-catharacta-spp
#15
Alice Carravieri, Yves Cherel, Maud Brault-Favrou, Carine Churlaud, Laurent Peluhet, Pierre Labadie, Hélène Budzinski, Olivier Chastel, Paco Bustamante
Seabirds integrate bioaccumulative contaminants via food intake and have revealed geographical trends of contamination in a variety of ecosystems. Pre-fledging seabird chicks are particularly interesting as bioindicators of chemical contamination, because concentrations in their tissues reflect primarily dietary sources from the local environment. Here we measured 14 trace elements and 18 persistent organic pollutants (POPs) in blood of chicks of skuas that breed in four sites encompassing a large latitudinal range within the southern Indian Ocean, from Antarctica (Adélie Land, south polar skua Catharacta maccormicki), through subantarctic areas (Crozet and Kerguelen Islands, brown skua C...
May 29, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28570974/photodegradation-of-micropollutants-using-v-uv-uv-c-processes-triclosan-as-a-model-compound
#16
Alfiya Yuval, Friedler Eran, Westphal Janin, Olsson Oliver, Dubowski Yael
Non-potable reuse of treated wastewater is becoming widespread as means to address growing water scarcity. Removal of micropollutants (MPs) from such water often requires advanced oxidation processes using OH radicals. OH can be generated in-situ via water photolysis under vacuum-UV (λ<200nm) irradiation. The aim of this study was to investigate the potential of unmasking V-UV radiation from low pressure Hg lamps (emitting at 185 and 254nm), commonly used in decentralized treatment systems, for enhancing MPs removal efficiency...
May 29, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28555279/mercury-uptake-by-halophytes-in-response-to-a-long-term-contamination-in-coastal-wetland-salt-marshes-northern-adriatic-sea
#17
E Pellegrini, E Petranich, A Acquavita, J Canário, A Emili, S Covelli
Mercury (Hg) distribution in saltmarsh sediments and in three selected halophytes (Limonium narbonense, Sarcocornia fruticosa and Atriplex portulacoides) of a wetland system (Marano and Grado Lagoon, Italy) following a contamination gradient in sediments was investigated. The Hg uptake was evaluated at the root system level by calculating the enrichment factor (EF) and in the aboveground tissues by means of the translocation factor (TF). The related methylmercury (MeHg) concentrations in the halophytes were also investigated with regard to the location of the sites and their degree of contamination...
May 29, 2017: Environmental Geochemistry and Health
https://www.readbyqxmd.com/read/28551139/in-vitro-study-on-antagonism-mechanism-of-glutathione-sodium-selenite-and-mercuric-chloride
#18
Yu Qiao, Xi Huang, Beibei Chen, Man He, Bin Hu
It has been broadly recognized that the antagonism between selenium (Se) and mercury (Hg) can reduce the toxicity of mercury in organism. Glutathione (GSH) can participate in the metabolism of Se and Hg in vivo and promote the formation of low-toxic Hg-Se complexes, which is a vital way of detoxification for Hg. In this paper, the reaction mechanism of GSH-Se(IV) binary system, GSH-Hg(II) binary system and GSH-Se(IV)-Hg(II) ternary system were systematically studied from the aspects of stoichiometry, thermodynamics and kinetics, via hyphenated techniques including high performance liquid chromatography (HPLC)-ultraviolet (UV) detection, HPLC-inductively coupled plasma mass spectrometry (ICP-MS) and HPLC-electrospray ionization mass spectrometry (ESI-MS)...
August 15, 2017: Talanta
https://www.readbyqxmd.com/read/28547667/metalloproteomics-approach-to-analyze-mercury-in-breast-milk-and-hair-samples-of-lactating-women-in-communities-of-the-amazon-basin-brazil
#19
M R Cerbino, José Cavalcante Souza Vieira, C P Braga, G Oliveira, I F Padilha, T M Silva, L F Zara, N J Silva, P M Padilha
Mercury is a potentially toxic element that is present in the environment of the Brazilian Amazon and is responsible for adverse health effects in humans. This study sought to assess possible protein biomarkers of mercury exposure in breast milk samples from lactating women in the Madeira and Negro Rivers in the Brazilian Amazon. The mercury content of hair samples of lactating women was determined, and the proteome of breast milk samples was obtained using two-dimensional electrophoresis after protein precipitation with acetone...
May 25, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28545513/cross-sectional-assessment-of-infants-exposure-to-toxic-metals-through-breast-milk-in-a-prospective-cohort-study-of-mining-communities-in-ghana
#20
David Kwaku Bansa, Adolf Kofi Awua, Rose Boatin, Theodosia Adom, Edward Christian Brown-Appiah, Kennedy Kwame Amewosina, Akusika Diaba, Dominic Datoghe, Wilhelmina Okwabi
BACKGROUND: Although breastfeeding of infants is recommended globally, the fact that maternal toxic metal stores are mobilised into breast milk implies infants, whose mothers live and work in mining communities, are at risk of multiple exposure to mining related toxic metals, such as Lead (Pb), Mercury (Hg), Cadmium (Cd) and Arsenic (As), through breast milk intake, in addition to in utero exposure. METHOD: A total of 114 mother-baby pairs, recruited from two community hospitals servicing mining communities in two different regions in Ghana (57 each), were involved in this study...
May 25, 2017: BMC Public Health
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