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Mercury toxicity

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https://www.readbyqxmd.com/read/28527323/revealing-the-ability-of-a-novel-polysaccharide-bioflocculant-in-bioremediation-of-heavy-metals-sensed-in-a-vibrio-bioluminescence-reporter-assay
#1
Arya Sajayan, G Seghal Kiran, S Priyadharshini, Navya Poulose, Joseph Selvin
A bioflocculant-producing bacterial strain, designated MSI021, was isolated from the marine sponge Dendrilla nigra and demonstrated 94% flocculation activity in a kaolin clay suspension. MSI021 was identified as Bacillus cereus based on phylogenetic affiliation and biochemical characteristics. The purified extra-cellular bioflocculant was chemically elucidated as a polysaccharide molecule. The polysaccharide bioflocculant was stable under both acidic and alkaline conditions (pH 2.0-10.0) and temperatures up to 100 °C...
May 17, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28527002/design-and-development-of-amperometric-biosensor-for-the-detection-of-lead-and-mercury-ions-in-water-matrix-a-permeability-approach
#2
Manju Bhargavi Gumpu, Uma Maheswari Krishnan, John Bosco Balaguru Rayappan
Intake of water contaminated with lead (Pb(2+)) and mercury (Hg(2+)) ions leads to various toxic effects and health issues. In this context, an amperometric urease inhibition-based biosensor was developed to detect Pb(2+) and Hg(2+) ions in water matrix. The modified Pt/CeO2/urease electrode was fabricated by immobilizing CeO2 nanoparticles and urease using a semi-permeable adsorption layer of nafion. With urea as a substrate, urease catalytic activity was examined through cyclic voltammetry. Further, maximum amperometric inhibitive response of the modified Pt/CeO2/urease electrode was observed in the presence of Pb(2+) and Hg(2+) ions due to the urease inhibition at specific potentials of -0...
May 20, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28526320/mercury-exposure-induces-cytoskeleton-disruption-and-loss-of-renal-function-through-epigenetic-modulation-of-mmp9-expression
#3
Hafizurrahman Khan, Radha Dutt Singh, Ratnakar Tiwari, Siddhartha Gangopadhyay, Somendu Kumar Roy, Dhirendra Singh, Vikas Srivastava
Mercury is one of the major heavy metal pollutants occurring in elemental, inorganic and organic forms. Due to ban on most inorganic mercury containing products, human exposure to mercury generally occurs as methylmercury (MeHg) by consumption of contaminated fish and other sea food. Animal and epidemiological studies indicate that MeHg affects neural and renal function. Our study is focused on nephrotoxic potential of MeHg. In this study, we have shown for the first time how MeHg could epigenetically modulate matrix metalloproteinase 9(MMP9) to promote nephrotoxicity using an animal model of sub chronic MeHg exposure...
May 16, 2017: Toxicology
https://www.readbyqxmd.com/read/28507557/exogenous-glutathione-enhances-mercury-tolerance-by-inhibiting-mercury-entry-into-plant-cells
#4
Yeon-Ok Kim, Hyeun-Jong Bae, Eunjin Cho, Hunseung Kang
Despite the increasing understanding of the crucial roles of glutathione (GSH) in cellular defense against heavy metal stress as well as oxidative stress, little is known about the functional role of exogenous GSH in mercury (Hg) tolerance in plants. Here, we provide compelling evidence that GSH contributes to Hg tolerance in diverse plants. Exogenous GSH did not mitigate the toxicity of cadmium (Cd), copper (Cu), or zinc (Zn), whereas application of exogenous GSH significantly promoted Hg tolerance during seed germination and seedling growth of Arabidopsis thaliana, tobacco, and pepper...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28500894/mercury-induced-oxidative-stress-dna-damage-and-activation-of-antioxidative-system-and-hsp70-induction-in-duckweed-lemna-minor
#5
Tingting Zhang, Qianqian Lu, Chunlei Su, Yaru Yang, Dan Hu, Qinsong Xu
Mercury uptake and its effects on physiology, biochemistry and genomic stability were investigated in Lemna minor after 2 and 6d of exposure to 0-30μM Hg. The accumulation of Hg increased in a concentration- and duration-dependent manner, and was positively correlated with the leaf damage. Oxidative stress after Hg exposure was evidenced in L. minor by a significant decrease in photosynthetic pigments, an increase in malondialdehyde and lipoxygenase activities (total enzyme activity and isoenzymes activity)...
May 10, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28498799/dietary-luteolin-attenuates-chronic-liver-injury-induced-by-mercuric-chloride-via-the-nrf2-nf-%C3%AE%C2%BAb-p53-signaling-pathway-in-rats
#6
Haili Zhang, Xiao Tan, Daqian Yang, Jingjing Lu, Biying Liu, Ruiqi Baiyun, Zhigang Zhang
Mercury exposure is a common cause of metal poisoning which is biotransformed to highly toxic metabolites thus eliciting biochemical alterations and oxidative stress. Luteolin, a phenolic compound found in many natural products, has multiple biological functions. Our study was aimed to explore the biological effects of luteolin in a liver injury model induced in rats by mercuric chloride (HgCl2). Criteria for injury included liver enzyme, glutathione and malondialdehyde levels, histopathology, TUNEL assay, hepatocyte viability and reactive oxygen species levels...
April 21, 2017: Oncotarget
https://www.readbyqxmd.com/read/28498787/spatial-and-temporal-variability-of-atmospheric-mercury-concentrations-emitted-from-a-coal-fired-power-plant-in-mexico
#7
Gilberto Fuentes, Bravo A Humberto, Sosa E Rodolfo, Rosas A Sergio, Magaña R Víctor, Caetano D Ernesto, Vázquez C Gustavo
Atmospheric mercury in the environment as a result of the consumption of fossil fuels, such as coal used in electricity generation, has gained increased attention worldwide because of its toxicity, atmospheric persistence, and bioaccumulation. Determining or predicting the concentration of this pollutant in ambient air is essential for determining sensitive areas requiring health protection. This study investigated the spatiotemporal variability of gaseous elemental mercury (GEM) concentrations and its dry deposition surrounding the Presidente Plutarco Elías Calles, (CETEPEC) coal-fired power plant, located on Mexico's Pacific coast...
May 12, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/28498344/mercury-in-children-current-state-on-exposure-through-human-biomonitoring-studies
#8
REVIEW
Flavia Ruggieri, Costanza Majorani, Francesco Domanico, Alessandro Alimonti
Mercury (Hg) in children has multiple exposure sources and the toxicity of Hg compounds depends on exposure routes, dose, timing of exposure, and developmental stage (be it prenatal or postnatal). Over the last decades, Hg was widely recognized as a threat to the children's health and there have been acknowledgements at the international level of the need of a global policy intervention-like the Minamata treaty-aimed at reducing or preventing Hg exposure and protecting the child health. National human biomonitoring (HBM) data has demonstrated that low levels of exposure of Hg are still an important health concern for children, which no one country can solve alone...
May 12, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28498320/chronic-kidney-disease-and-exposure-to-nephrotoxic-metals
#9
REVIEW
Sarah E Orr, Christy C Bridges
Chronic kidney disease (CKD) is a common progressive disease that is typically characterized by the permanent loss of functional nephrons. As injured nephrons become sclerotic and die, the remaining healthy nephrons undergo numerous structural, molecular, and functional changes in an attempt to compensate for the loss of diseased nephrons. These compensatory changes enable the kidney to maintain fluid and solute homeostasis until approximately 75% of nephrons are lost. As CKD continues to progress, glomerular filtration rate decreases, and remaining nephrons are unable to effectively eliminate metabolic wastes and environmental toxicants from the body...
May 12, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28494418/zingiber-officinale-and-6-gingerol-alleviate-liver-and-kidney-dysfunctions-and-oxidative-stress-induced-by-mercuric-chloride-in-male-rats-a-protective-approach
#10
Deepmala Joshi, Sunil Kumar Srivastav, Sateesh Belemkar, Vaibhav A Dixit
Mercury toxicity is an emerging problem in the world as its concentration is rising continuously due to increased industrial, medicinal and domestic uses. Exposure to mercury represents a serious challenge to humans and other living biomes. The aim of the present study was to assess the protective effect of natural products as Zingiber officinale extract and its active compound (6-gingerol) against mercuric chloride-induced hepatorenal toxicity and oxidative stress in male rats. Male Sprague-Dawley rats (150±10g, n=6 per group) were administered HgCl2 (12μmol/kg, ip; once only) the treatment of Zingiber officinale Rosc...
May 8, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28480508/cultivation-of-solanum-tuberosum-in-a-former-mining-district-for-a-safe-human-consumption-integrating-simulated-digestion
#11
M J Sierra, R López-Nicolás, C A González-Bermúdez, C Frontela-Saseta, R Millán
BACKGROUND: Potato (Solanum tuberosum) is a global crop and by far the most important non-cereal crop in the world. Therefore, it is necessary to assure its safe consumption. This is especially relevant in the case of its cultivation in abandoned mining areas, where the population tends to return to agriculture. In the present work, the objective is to evaluate the contribution to the diet of nutrients and contaminants of potato grown in soils from the Almadén area (mining district) by studying the intestinal absorption (in vitro) of the tuber taking into account the preparation methods for its consumption...
May 8, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28471730/a-vegetable-launaea-taraxacifolia-mitigated-mercuric-chloride-alteration-of-the-microanatomy-of-rat-brain
#12
Olatunde Owoeye, Ganiyu O Arinola
Mercuric chloride is an environmental pollutant that affects the nervous systems of mammals. Oxidative damage is one of the mechanisms of its toxicity, and antioxidants should mitigate this effect. A vegetable with antioxidant activity is Launaea taraxacifolia, whose ethanolic extract (EELT) was investigated in this experiment to determine its effect against mercuric chloride (MC) intoxication in rat brain. Thirty male Wistar rats were randomly assigned into five groups (n = 6) as follows: control; propylene glycol; EELT (400 mg/kg bwt) for 19 days; MC (HgCl2) (4 mg/bwt) for 5 days from day 15 of the experiment; EELT+ MC, EELT (400 mg/kg bwt) for 14 days + MC (4 mg/bwt) for 5 days from day 15 of the experiment...
November 2, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28470495/removal-of-heavy-metal-ions-from-wastewaters-using-dendrimer-functionalized-multi-walled-carbon-nanotubes
#13
Daniela Iannazzo, Alessandro Pistone, Ida Ziccarelli, Claudia Espro, Signorino Galvagno, Salvatore V Giofré, Roberto Romeo, Nicola Cicero, Giuseppe D Bua, Giuseppe Lanza, Laura Legnani, Maria A Chiacchio
Dendrimer-functionalized multi-walled carbon nanotubes (MWCNT) for heavy metal ion removal from wastewaters were developed. Triazole dendrimers (TD) were built directly onto the carbon nanotube surface by successive click chemistry reactions affording the zero- and first-generation dendrimer-functionalized MWCNT (MWCNT-TD1 and MWCNT-TD2). The Moedritzer-Irani reaction carried out on the amino groups present on the MWCNT-TD2 sample gave the corresponding α-aminophosphonate nanosystem MWCNT-TD2P. Both MWCNT-TD2 and MWCNT-TD2P nanosystems have been characterized by physical, chemical, and morphological analyses...
May 3, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28451726/toxicity-of-inorganic-mercury-to-native-australian-grass-grown-in-three-different-soils
#14
Khandaker Rayhan Mahbub, Mohammed Kader, Kannan Krishnan, Maurizio Labbate, Ravi Naidu, Mallavarapu Megharaj
In this study, three native Australian grasses namely Iseilema membranaceum (Barcoo), Dichanthium sericeum (Queensland Blue) and Sporobolus africanus (Tussock) were grown in three different soils spiked with different concentrations of inorganic mercury and the root elongation was monitored up to 28 days following the germination. Results showed that mercury at certain concentrations significantly inhibited the root growth of all three tested native grasses grown in three soils, however, the toxicity was less in the soil with high organic carbon content and acidic pH...
June 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28448157/protein-changes-in-lepidium-sativum-l-exposed-to-hg-during-soil-phytoremediation
#15
Beata Smolinska, Agnieszka Szczodrowska, Joanna Leszczynska
Due to soil pollution by mercury the investigations have been provided to find the best technique of soil reclamation. In this study we examined Lepidium sativum L. as a plant useful for Hg phytoextraction. The simultaneous application of compost and thiosulphate was explored as a possible method of process enhancement. The investigations of plant protein changes during assisted Hg phytoextraction were also provided. The results of the study show that combined use of compost and thiosulphate significantly increased both the total Hg accumulation and its translocation to aerial plant tissues...
April 27, 2017: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/28439753/abating-mercury-exposure-in-young-children-should-include-thimerosal-free-vaccines
#16
REVIEW
José G Dórea
Pediatric immunization is essential to prevent, control and eradicate children`s infectious diseases. Newborns and infants in less developed countries have a concentrated schedule of Thimerosal-containing vaccines (TCVs); pregnant mothers are also immunized with TCVs. Metabolic changes during early development are demonstrably an important risk factor for ethylmercury (EtHg) effects on neurodevelopment, while exposure to Thimerosal sensitizes susceptible individuals to life-long contact dermatitis. Concerns regarding toxicity of Hg have moved rich nations to withdraw it from medicines and, in particular, Thimerosal from pediatric vaccines; it has been more than 20 years since rich countries started using Thimerosal-free vaccines...
April 24, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28438339/mercury-arsenic-cadmium-and-lead-in-two-commercial-shark-species-sphyrna-lewini-and-caraharinus-porosus-in-trinidad-and-tobago
#17
Azad Mohammed, Terry Mohammed
Sharks are long-lived apex predators which can accumulate toxic metals such as mercury and arsenic. Samples of Sphyrna lewini and Carcharinus porosus were collected from two commercial fish landing sites in Trinidad. Heavy metal concentrations were determined in the muscle, dorsal fin, vertebrae and liver using atomic absorption spectrometric. The provisional tolerable weekly intake (PTWI) and target hazard quotient (THQ) were determined to assess the potential health risks to consumers. Mercury levels ranged between 74-1899μg/kg in S...
April 21, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28427493/hair-mercury-levels-and-their-relationship-with-seafood-consumption-among-preschool-children-in-shanghai
#18
Jin Yan, Zhen Yan Gao, Ju Wang, Chong Huai Yan
Mercury is a global pollutant. Children are vulnerable to environmental toxicants. Seafood consumption is a major source of methylmercury exposure. In order to ascertain children's mercury exposure levels and study their relationship with seafood consumption, we conducted a cross-sectional study among preschool children in Shanghai. According to our data, the geometric mean of the mercury levels in children's hair was 191.9 (95% CI: 181.8, 202.4) μg/kg. These results indicate that high income may be a predictor of elevated mercury levels in children's hair...
March 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28423187/characterization-of-the-binding-capacity-of-mercurial-species-in-lactobacillus-strains
#19
Cristina Alcántara, Carlos Jadán-Piedra, Dinoraz Vélez, Vicenta Devesa, Manuel Zúñiga, Vicente Monedero
BACKGROUND: Metal sequestration by bacteria has been proposed as a strategy to counteract metal contamination in foodstuffs. Lactobacilli can interact with metals, but studies with important foodborne metals such as inorganic [Hg(II)] or organic (CH3 Hg) mercury are lacking. Lactobacilli were evaluated for their potential to bind these contaminants and the nature of the interaction was assessed by the use of metal competitors, chemical and enzymatical treatments and mutants affected in the cell-wall structure...
April 19, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28420130/gaseous-elemental-mercury-and-total-and-leached-mercury-in-building-materials-from-the-former-hg-mining-area-of-abbadia-san-salvatore-central-italy
#20
Orlando Vaselli, Barbara Nisi, Daniele Rappuoli, Jacopo Cabassi, Franco Tassi
Mercury has a strong environmental impact since both its organic and inorganic forms are toxic, and it represents a pollutant of global concern. Liquid Hg is highly volatile and can be released during natural and anthropogenic processes in the hydrosphere, biosphere and atmosphere. In this study, the distribution of Gaseous Elemental Mercury (GEM) and the total and leached mercury concentrations on paint, plaster, roof tiles, concrete, metals, dust and wood structures were determined in the main buildings and structures of the former Hg-mining area of Abbadia San Salvatore (Siena, Central Italy)...
April 15, 2017: International Journal of Environmental Research and Public Health
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