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Mercury poisoning

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https://www.readbyqxmd.com/read/27920011/the-interwoven-history-of-mercury-poisoning-in-ontario-and-japan
#1
Adam Mosa, Jacalyn Duffin
No abstract text is available yet for this article.
December 5, 2016: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/27916058/-advances-in-diagnosis-and-treatment-of-patients-with-mercury-poisoning-associated-glomerulonephropathy
#2
A B Qin, F D Zhou, M H Zhao
No abstract text is available yet for this article.
December 1, 2016: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/27872646/mercury-vapour-long-lasting-exposure-lymphocyte-muscarinic-receptors-as-neurochemical-markers-of-accidental-intoxication
#3
E Roda, A Giampreti, S Vecchio, P Apostoli, T Coccini
Introduction. Chronic poisoning may result in home setting after mercury (Hg) vapours inhalation from damaged devices. We report a chronic, nonoccupational Hg poisoning due to 10-year indoor exposure to mercury spillage. Case Report. A 72-year-old man with polyneuropathy of suspected toxic origin. At hospitalization, toxicological clinical evaluations confirmed the altered neurological picture documented across the last decade. Periodic blood and urine Hg levels (BHg, UHg) monitoring were performed from admission (t0), until 1 year later (t2), paralleled by blood neurochemical markers assessment, that is, lymphocytes muscarinic receptors (l-MRs)...
2016: Case Reports in Medicine
https://www.readbyqxmd.com/read/27858849/mercury-poisoning-caused-by-chinese-folk-prescription-cfp-a-case-report-and-analysis-of-both-cfp-and-quackery
#4
Tingting Mo, Si Sun, Yongyi Wang, Dong Luo, Bin Peng, Yinyin Xia
BACKGROUND: Though as a heavy metal, mercury has a long history in the culture of traditional Chinese medicine (TCM). Also until now, we can still find evidence of mercury in some Chinese folk prescriptions (CFP)s in China. CASE: We report a case of a 35-year-old rural woman, who took almost 35 g of Hg2O orally to treat her itchy skin followed a folk prescription of an unlicensed practitioners engaging in quackery (UPEQ), which lead to dark red bloody stool and mucus, nausea, and numbness...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27853236/regulation-of-sirt1-nrf2-tnf-%C3%AE-signaling-pathway-by-luteolin-is-critical-to-attenuate-acute-mercuric-chloride-exposure-induced-hepatotoxicity
#5
Daqian Yang, Xiao Tan, Zhanjun Lv, Biying Liu, Ruiqi Baiyun, Jingjing Lu, Zhigang Zhang
Inorganic mercury, though a key component of pediatric vaccines, is an environmental toxicant threatening human health via accumulating oxidative stress in part. Luteolin has been of great interest because of its antiinflammatory, anticarcinogenic and antioxidative effects. Here we hypothesized that luteolin would attenuate hepatotoxicity induced by acute inorganic mercury exposure. Kunming mice were treated with luteolin (100 mg/kg) 24 h after administration of 4 mg/kg mercuric chloride (HgCl2). The results showed that luteolin ameliorated HgCl2 induced anemia and hepatotoxicity, regulating radical oxygen species (ROS) production and hepatocyte viability in vitro and oxidative stress and apoptosis in vivo...
November 17, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27837412/skin-bleaching-and-dermatologic-health-of-african-and-afro-caribbean-populations-in-the-us-new-directions-for-methodologically-rigorous-multidisciplinary-and-culturally-sensitive-research
#6
Emma K T Benn, Andrew Alexis, Nihal Mohamed, Yan-Hong Wang, Ikhlas A Khan, Bian Liu
Skin-bleaching practices, such as using skin creams and soaps to achieve a lighter skin tone, are common throughout the world and are triggered by cosmetic reasons that oftentimes have deep historical, economic, sociocultural, and psychosocial roots. Exposure to chemicals in the bleaching products, notably, mercury (Hg), hydroquinone, and steroids, has been associated with a variety of adverse health effects, such as Hg poisoning and exogenous ochronosis. In New York City (NYC), skin care product use has been identified as an important route of Hg exposure, especially among Caribbean-born blacks and Dominicans...
December 2016: Dermatology and Therapy
https://www.readbyqxmd.com/read/27833648/alternative-drugs-go-global-possible-lead-and-or-mercury-intoxication-from-imported-natural-health-products-and-a-need-for-scientifically-evaluated-poisoning-monitoring-from-environmental-exposures
#7
Lygia Therese Budnik, Xaver Baur, Volker Harth, Axel Hahn
BACKGROUND: With increases in globalization, cultural remedies from Chinese, Ayurvedic, Arab and other traditions have become more available to international consumers, offering unfamiliar "Natural Health Products" (NHP), used as alternative medicine or supplementary medicine. Contamination with toxic ingredients including lead, mercury, arsenic, and other toxic elements has been documented in several of these products from various parts of the globe, particularly from some parts of Asia and the Orient...
2016: Journal of Occupational Medicine and Toxicology
https://www.readbyqxmd.com/read/27780711/mercury-and-protein-thiols-stimulation-of-mitochondrial-f1fo-atpase-and-inhibition-of-respiration
#8
Salvatore Nesci, Fabiana Trombetti, Maurizio Pirini, Vittoria Ventrella, Alessandra Pagliarani
In spite of the known widespread toxicity of mercury, its impact on mitochondrial bioenergetics is a still poorly explored topic. Even if many studies have dealt with mercury poisoning of mitochondrial respiration, as far as we are aware Hg(2+) effects on individual complexes are not so clear. In the present study changes in swine heart mitochondrial respiration and F1FO-ATPase (F-ATPase) activity promoted by micromolar Hg(2+) concentrations were investigated. Hg(2+) was found to inhibit the respiration of NADH-energized mitochondria, whereas it was ineffective when the substrate was succinate...
October 22, 2016: Chemico-biological Interactions
https://www.readbyqxmd.com/read/27744257/stabilization-of-mercury-over-mn-based-oxides-speciation-and-reactivity-by-temperature-programmed-desorption-analysis
#9
Haomiao Xu, Yongpeng Ma, Wenjun Huang, Jian Mei, Songjian Zhao, Zan Qu, Naiqiang Yan
Mercury temperature-programmed desorption (Hg-TPD) method was employed to clarify mercury species over Mn-based oxides. The elemental mercury (Hg(0)) removal mechanism over MnOx was ascribed to chemical-adsorption. HgO was the primary mercury chemical compound adsorbed on the surface of MnOx. Rare earth element (Ce), main group element (Sn) and transition metal elements (Zr and Fe) were chosen for the modification of MnOx. Hg-TPD results indicated that the binding strength of mercury on these binary oxides followed the order of Sn-MnOx<Ce-MnOx∼MnOx<Fe-MnOx<Zr-MnOx...
September 14, 2016: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/27692553/-accidental-mercury-poisoning-in-a-12-year-old-girl
#10
F Alby-Laurent, N Honoré-Goldman, A Cavau, N Bellon, S Allali, V Abadie
INTRODUCTION: Exposure to metallic mercury can cause severe accidental intoxications in children, whose clinical symptoms can vary depending on the route of administration, the dose, as well as the time and duration of the exposure. It has become unusual in France, yet it must be considered when taking a patient's medical history in cases of multisystemic involvement without a clear explanation. CLINICAL CASE: We report the case of a 12-year-old patient hospitalized because of a cough, poor general condition, chills, night sweats, psychomotor retardation, and skin lesions that had been developing for several weeks...
September 27, 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/27686425/saint-ioannis-lampadistis-the-first-possible-case-of-blindness-due-to-organic-mercury-poisoning-in-history
#11
Kleonikos A Tsakiris
Saint Ioannis Lampadistis is a Cypriot saint of the Greek Orthodox Church, widely venerated in his island of origin. He lived during the 11th century and was blinded by ingesting contaminated fish in the mountainous area of Galata, withdrew from civil life when he was 18, and died at the age of 22. The reason for his blindness remains unknown, though it is widely attributed to an unknown poison related to the copper mines of the region. As fish is the end reservoir of organic mercury, it is quite possible that his blindness was the result of heavy metal toxicity...
September 29, 2016: Journal of Medical Biography
https://www.readbyqxmd.com/read/27651086/mercury-poisoning-in-operational-settings-among-gilders
#12
P D Pigatto, A Ronchi, V Falabella, G Guzzi
No abstract text is available yet for this article.
October 2016: International Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/27636885/comparison-of-single-and-multiple-person-mercury-exposures
#13
Mathias B Forrester
Elemental and organic mercury are extremely toxic. All mercury exposures reported to Texas poison centers during 2000-2013 were identified. The cases were divided into multiple- and single-person exposure groups and compared, including identification of statistically significant differences (SSDs). There were 6,521 single-person exposures and 214 multiple-person incidents involving 734 total persons; 45% and 27% of the multiple- and single-person exposures, respectively, involved patients aged 6-19 years (SSD)...
September 16, 2016: Archives of Environmental & Occupational Health
https://www.readbyqxmd.com/read/27620881/the-organic-mercury-compounds-methylmercury-and-ethylmercury-inhibited-ciliary-movement-of-ventricular-ependymal-cells-in-the-mouse-brain-around-the-concentrations-reported-for-human-poisoning
#14
Shigeru Yoshida, Shinsaku Matsumoto, Takuya Kanchika, Teruki Hagiwara, Takeshi Minami
Functions of the nervous system are supported by the flow of cerebrospinal fluid (CSF), which is driven by the ciliary beating of ventricular ependymal cells. The aim of the present study was to examine whether methylmercury (MeHg), a substance with potent neurotoxicity in humans, affects the ciliary movement. The effects of another organic mercury compound, ethylmercury (EtHg), were also assessed for comparison. Toxicity of MeHg or EtHg was evaluated by measuring alterations in the ciliary beat frequency of ependymal cells lining the third ventricle of mouse brain slices...
September 13, 2016: Neurotoxicology
https://www.readbyqxmd.com/read/27575364/altered-fine-motor-function-at-school-age-in-inuit-children-exposed-to-pcbs-methylmercury-and-lead
#15
Olivier Boucher, Gina Muckle, Pierre Ayotte, Eric Dewailly, Sandra W Jacobson, Joseph L Jacobson
BACKGROUND: Motor deficits have frequently been reported in methylmercury (MeHg) poisoning in adults. However, whether exposure to neurotoxic contaminants from environmental sources early in life is associated with neuromotor impairments has received relatively little attention. This study examines the relation of developmental exposure to MeHg, polychlorinated biphenyls (PCBs), and lead to motor function in school-age Inuit children exposed through their traditional diet. METHODS: In a prospective study in Nunavik, children (mean age=11...
October 2016: Environment International
https://www.readbyqxmd.com/read/27542163/elevated-mercury-bound-to-serum-proteins-in-methylmercury-poisoned-rats-after-selenium-treatment
#16
Yunyun Li, Yuqin Fan, Jiating Zhao, Xiaohan Xu, Hui Jing, Lihai Shang, Yuxi Gao, Bai Li, Yu-Feng Li
Methylmercury is a toxic pollutant and is generated by microbial methylation of elemental or inorganic mercury in the environment. Previous study found decreased hepatic MDA levels and urinary mercury levels in methylmercury poisoned rats after sodium selenite treatment. This study further found increased mercury levels in serum samples from methylmercury poisoned rats after selenium treatment. By using size exclusion chromatography coupled to inductively coupled plasma mass spectrometry, three Hg- binding protein fractions and two Se-binding protein fractions were identified with the molecular weight of approximately 21, 40, and 75 kDa and of 40 and 75 kDa, respectively...
October 2016: Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
https://www.readbyqxmd.com/read/27511528/nickel-catalyzed-transfer-hydrogenation-of-ketones-using-ethanol-as-a-solvent-and-a-hydrogen-donor
#17
Nahury Castellanos-Blanco, Alma Arévalo, Juventino J García
We report a nickel(0)-catalyzed direct transfer hydrogenation (TH) of a variety of alkyl-aryl, diaryl, and aliphatic ketones with ethanol. This protocol implies a reaction in which a primary alcohol serves as a hydrogen atom source and solvent in a one-pot reaction without any added base. The catalytic activity of the nickel complex [(dcype)Ni(COD)] (e) (dcype: 1,2-bis(dicyclohexyl-phosphine)ethane, COD: 1,5-cyclooctadiene), towards transfer hydrogenation (TH) of carbonyl compounds using ethanol as the hydrogen donor was assessed using a broad scope of ketones, giving excellent results (up to 99% yield) compared to other homogeneous phosphine-nickel catalysts...
September 14, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/27338817/inhalational-mercury-toxicity-from-artisanal-gold-extraction-reported-to-the-oregon-poison-center-2002-2015
#18
Matthew J Noble, Stewart L Decker, B Zane Horowitz
CONTEXT: Mercury exposure has been described among small-scale gold mining communities in developing countries, but reports of inhalational mercury toxicity among home gold extractors in the US remain uncommon. OBJECTIVE: We sought to identify inhalational mercury exposures and toxicity among artisanal gold extractors. METHODS: This is an observational case series of a single Poison Center database from 2002-2015. We review all cases of "mercury" or "mercury inhalation" exposures, with detailed description of a recent representative case...
June 24, 2016: Clinical Toxicology
https://www.readbyqxmd.com/read/27259347/evidence-of-the-direct-adsorption-of-mercury-in-human-hair-during-occupational-exposure-to-mercury-vapour
#19
Silvia Queipo Abad, Pablo Rodríguez-González, J Ignacio García Alonso
We have found clear evidence of direct adsorption of mercury in human hair after the occupational exposure to mercury vapour. We have performed both longitudinal analysis of human hair by laser ablation ICP-MS and speciation analysis by gas chromatography ICP-MS in single hair strands of 5 individuals which were occupationally exposed to high levels of mercury vapour and showed acute mercury poisoning symptoms. Hair samples, between 3.5 and 11cm long depending on the individual, were taken ca. three months after exposure...
July 2016: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27214290/paracelsus-revisited-the-dose-concept-in-a-complex-world
#20
REVIEW
Philippe Grandjean
At the time that Paracelsus coined his famous dictum, 'What is there that is not poison? All things are poison and nothing is without poison. Solely the dose determines that a thing is not a poison', embryonic toxicology was a fairly focused discipline that mainly dealt with occupational poisonings and side effects of pharmaceuticals, such as mercury. While Paracelsus paved the way for the modern threshold concept and the no-adverse effect level, modern-day toxicology is now tussling with highly complex issues, such as developmental exposures, genetic predisposition and other sources of hypersusceptibility, multiple causes of underestimated toxicity, and the continuous presence of uncertainty, even in regard to otherwise well-studied mercury compounds...
August 2016: Basic & Clinical Pharmacology & Toxicology
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