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Mercury poisoning

Haomiao Xu, Yongpeng Ma, Wenjun Huang, Jian Mei, Songjian Zhao, Zan Qu, Naiqiang Yan
Mercury temperature-programmed desorption (Hg-TPD) method was employed to clarify mercury species over Mn-based oxides. The elemental mercury (Hg(0)) removal mechanism over MnOx was ascribed to chemical-adsorption. HgO was the primary mercury chemical compound adsorbed on the surface of MnOx. Rare earth element (Ce), main group element (Sn) and transition metal elements (Zr and Fe) were chosen for the modification of MnOx. Hg-TPD results indicated that the binding strength of mercury on these binary oxides followed the order of Sn-MnOx<Ce-MnOx∼MnOx<Fe-MnOx<Zr-MnOx...
September 14, 2016: Journal of Hazardous Materials
F Alby-Laurent, N Honoré-Goldman, A Cavau, N Bellon, S Allali, V Abadie
INTRODUCTION: Exposure to metallic mercury can cause severe accidental intoxications in children, whose clinical symptoms can vary depending on the route of administration, the dose, as well as the time and duration of the exposure. It has become unusual in France, yet it must be considered when taking a patient's medical history in cases of multisystemic involvement without a clear explanation. CLINICAL CASE: We report the case of a 12-year-old patient hospitalized because of a cough, poor general condition, chills, night sweats, psychomotor retardation, and skin lesions that had been developing for several weeks...
September 27, 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
Kleonikos A Tsakiris
Saint Ioannis Lampadistis is a Cypriot saint of the Greek Orthodox Church, widely venerated in his island of origin. He lived during the 11th century and was blinded by ingesting contaminated fish in the mountainous area of Galata, withdrew from civil life when he was 18, and died at the age of 22. The reason for his blindness remains unknown, though it is widely attributed to an unknown poison related to the copper mines of the region. As fish is the end reservoir of organic mercury, it is quite possible that his blindness was the result of heavy metal toxicity...
September 29, 2016: Journal of Medical Biography
P D Pigatto, A Ronchi, V Falabella, G Guzzi
No abstract text is available yet for this article.
October 2016: International Journal of Occupational and Environmental Medicine
Mathias B Forrester
Elemental and organic mercury are extremely toxic. All mercury exposures reported to Texas poison centers during 2000-2013 were identified. The cases were divided into multiple- and single-person exposure groups and compared, including identification of statistically significant differences (SSDs). There were 6,521 single-person exposures and 214 multiple-person incidents involving 734 total persons; 45% and 27% of the multiple- and single-person exposures, respectively, involved patients aged 6-19 years (SSD)...
September 16, 2016: Archives of Environmental & Occupational Health
Shigeru Yoshida, Shinsaku Matsumoto, Takuya Kanchika, Teruki Hagiwara, Takeshi Minami
Functions of the nervous system are supported by the flow of cerebrospinal fluid (CSF), which is driven by the ciliary beating of ventricular ependymal cells. The aim of the present study was to examine whether methylmercury (MeHg), a substance with potent neurotoxicity in humans, affects the ciliary movement. The effects of another organic mercury compound, ethylmercury (EtHg), were also assessed for comparison. Toxicity of MeHg or EtHg was evaluated by measuring alterations in the ciliary beat frequency of ependymal cells lining the third ventricle of mouse brain slices...
September 13, 2016: Neurotoxicology
Olivier Boucher, Gina Muckle, Pierre Ayotte, Eric Dewailly, Sandra W Jacobson, Joseph L Jacobson
BACKGROUND: Motor deficits have frequently been reported in methylmercury (MeHg) poisoning in adults. However, whether exposure to neurotoxic contaminants from environmental sources early in life is associated with neuromotor impairments has received relatively little attention. This study examines the relation of developmental exposure to MeHg, polychlorinated biphenyls (PCBs), and lead to motor function in school-age Inuit children exposed through their traditional diet. METHODS: In a prospective study in Nunavik, children (mean age=11...
October 2016: Environment International
Yunyun Li, Yuqin Fan, Jiating Zhao, Xiaohan Xu, Hui Jing, Lihai Shang, Yuxi Gao, Bai Li, Yu-Feng Li
Methylmercury is a toxic pollutant and is generated by microbial methylation of elemental or inorganic mercury in the environment. Previous study found decreased hepatic MDA levels and urinary mercury levels in methylmercury poisoned rats after sodium selenite treatment. This study further found increased mercury levels in serum samples from methylmercury poisoned rats after selenium treatment. By using size exclusion chromatography coupled to inductively coupled plasma mass spectrometry, three Hg- binding protein fractions and two Se-binding protein fractions were identified with the molecular weight of approximately 21, 40, and 75 kDa and of 40 and 75 kDa, respectively...
October 2016: Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
Nahury Castellanos-Blanco, Alma Arévalo, Juventino J García
We report a nickel(0)-catalyzed direct transfer hydrogenation (TH) of a variety of alkyl-aryl, diaryl, and aliphatic ketones with ethanol. This protocol implies a reaction in which a primary alcohol serves as a hydrogen atom source and solvent in a one-pot reaction without any added base. The catalytic activity of the nickel complex [(dcype)Ni(COD)] (e) (dcype: 1,2-bis(dicyclohexyl-phosphine)ethane, COD: 1,5-cyclooctadiene), towards transfer hydrogenation (TH) of carbonyl compounds using ethanol as the hydrogen donor was assessed using a broad scope of ketones, giving excellent results (up to 99% yield) compared to other homogeneous phosphine-nickel catalysts...
September 14, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
Matthew J Noble, Stewart L Decker, B Zane Horowitz
CONTEXT: Mercury exposure has been described among small-scale gold mining communities in developing countries, but reports of inhalational mercury toxicity among home gold extractors in the US remain uncommon. OBJECTIVE: We sought to identify inhalational mercury exposures and toxicity among artisanal gold extractors. METHODS: This is an observational case series of a single Poison Center database from 2002-2015. We review all cases of "mercury" or "mercury inhalation" exposures, with detailed description of a recent representative case...
June 24, 2016: Clinical Toxicology
Silvia Queipo Abad, Pablo Rodríguez-González, J Ignacio García Alonso
We have found clear evidence of direct adsorption of mercury in human hair after the occupational exposure to mercury vapour. We have performed both longitudinal analysis of human hair by laser ablation ICP-MS and speciation analysis by gas chromatography ICP-MS in single hair strands of 5 individuals which were occupationally exposed to high levels of mercury vapour and showed acute mercury poisoning symptoms. Hair samples, between 3.5 and 11cm long depending on the individual, were taken ca. three months after exposure...
July 2016: Journal of Trace Elements in Medicine and Biology
Philippe Grandjean
At the time that Paracelsus coined his famous dictum, 'What is there that is not poison? All things are poison and nothing is without poison. Solely the dose determines that a thing is not a poison', embryonic toxicology was a fairly focused discipline that mainly dealt with occupational poisonings and side effects of pharmaceuticals, such as mercury. While Paracelsus paved the way for the modern threshold concept and the no-adverse effect level, modern-day toxicology is now tussling with highly complex issues, such as developmental exposures, genetic predisposition and other sources of hypersusceptibility, multiple causes of underestimated toxicity, and the continuous presence of uncertainty, even in regard to otherwise well-studied mercury compounds...
August 2016: Basic & Clinical Pharmacology & Toxicology
Monia Perugini, Daniela Zezza, Serena Maria Rita Tulini, Maria Cesarina Abete, Gabriella Monaco, Annamaria Conte, Vincenzo Olivieri, Michele Amorena
The risk of Hg poisoning by eating seafood is considered real from the several international agencies that recommended, by fish consumption advisories, to pregnant women and young children to avoid or severely limit the consumption of the fish and shellfish with a high-range mercury levels. The analyses of two common species, European hake and Norway lobster, collected from an area of Central Adriatic Sea, reported high mercury levels in crustaceans. For Norway lobster total mercury exceeded, in six out of ten analysed pools, the recommended 0...
August 15, 2016: Marine Pollution Bulletin
J Dhanapriya, N Gopalakrishnan, V Arun, T Dineshkumar, R Sakthirajan, T Balasubramaniyan, M Haris
Mercury is a toxic heavy metal and occurs in organic and inorganic forms. Inorganic mercury includes elemental mercury and mercury salts. Mercury salts are usually white powder or crystals, and widely used in indigenous medicines and folk remedies in Asia. Inorganic mercury poisoning causes acute kidney injury (AKI) and gastrointestinal manifestations and can be life-threatening. We describe a case with unknown substance poisoning who developed AKI and disseminated intravascular coagulation (DIC). Renal biopsy showed acute tubular necrosis...
May 2016: Indian Journal of Nephrology
Enmin Ding, Qiuni Zhao, Ying Bai, Ming Xu, Liping Pan, Qingdong Liu, Bosheng Wang, Xianping Song, Jun Wang, Lin Chen, Baoli Zhu
BACKGROUND: Circulating microRNAs (miRNAs) have attracted interests as non-invasive biomarkers of physiological and pathological conditions. Several studies have examined the potential effects of mercury exposure on miRNAs expression profiles of general population environmentally exposed to mercury. The objective is to identify mercury-related miRNAs of female workers occupationally exposed to mercury. METHODS: In this case-control study, we used a microarray assay to detect the miRNA expression profiles in pooled plasma samples between (I) chronic mercury poisoning group; (II) mercury absorbing group and (III) control group in the discovery stage...
May 2016: Journal of Thoracic Disease
Ole Andersen, Jan Aaseth
Most acute and chronic human metal poisonings are due to oral or inhalation exposure. Almost 80% of published animal experiments on chelation in metal poisoning used single or repeated intraperitoneal, intramuscular or intravenous administration of metal and chelator, impeding extrapolation to clinical settings. Intramuscular administration of dimercaptopropanol (BAL) has until now been used in acute arsenic, lead, and mercury poisonings, but repeated BAL administration increased the brain uptake of As, Pb and Hg in experimental animals...
April 9, 2016: Journal of Trace Elements in Medicine and Biology
M Vahabzadeh, M Balali-Mood
Occupational exposure to elemental mercury vapor usually occurs through inhalation during its utilizations. This leads to a variety of adverse health effects. In some Islamic cities, this type of poisoning may occur during gilding of shrines using elemental mercury with gold. Herein, we report on three male patients aged 20-53 years, who were diagnosed with occupational metallic mercury poisoning due to gilding of a shrine. All patients presented with neuro-psychiatric disorders such as anxiety, loss of memory and concentration, and sleep disorders with high urinary mercury concentrations of 326-760 μg/L upon referring, 3-10 days after cessation of elemental mercury exposure...
April 2016: International Journal of Occupational and Environmental Medicine
Singankutti Mudalige Thanuja Nilushi Priyangika, W G S G Karunarathna, Isurujith Liyanage, Methsala Gunawardana, Buddini Dissanayake, Sumeda Udumalgala, Chamith Rosa, Thilina Samarasinghe, Pravin Wijesinghe, Aruna Kulatunga
BACKGROUND: Self-injection of elemental mercury is a rare finding especially in healthy people who are mentally sound. Early detection and removal of mercury from the body by chelation and physical removal of a stored injected site is required to prevent long term toxicity. CASE PRESENTATION: A 15 year old previously healthy girl presented with an acute febrile illness with a generalized maculopapular skin rash for 3 days with a preceding history of self-injection of mercury to both her forearms...
2016: BMC Research Notes
Iman Al-Saleh
Many studies have highlighted the widespread use of skin-lightening creams containing mercury by women during and after pregnancy to remove dark spots. Women, especially pregnant and lactating mothers using these products are at risk of mercury poisoning because sometimes it has no clinical symptoms, particularly during early exposure. Studies have shown that prenatal and postnatal mercury exposure can cause permanent neurological damage in children. Furthermore, mercury can cause women infertility and birth defects...
July 2016: International Journal of Hygiene and Environmental Health
Alexander K Mengele, Simon Kaufhold, Carsten Streb, Sven Rau
A new dyad consisting of a Ru(II) chromophore, a tetrapyridophenazine bridging ligand and a Rh(Cp*)Cl catalytic center, [Ru(tbbpy)2(tpphz)Rh(Cp*)Cl]Cl(PF6)2, acts as durable photocatalyst for hydrogen production from water. Catalytic activity is observed for more than 650 hours. Electrochemical investigations reveal that up to two electrons can be transferred to the catalytic center by a thermodynamically favorable intramolecular process, which has so far not been reported for similar tpphz based supramolecular photocatalysts...
April 21, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
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