Read by QxMD icon Read

Methanol poisoning

Dong-Mei Liu, Shu Zhou, Jie-Min Chen, Shu-Ya Peng, Wen-Tao Xia
UNLABELLED: Objective. To explore the potential effects of methanol and its metabolite, formic acid, on rat retina function. Methods. Sprague-Dawley rats were divided into 3- and 7-day groups and a control. Experimental groups were given methanol and the control group were provided saline by gavage. Retinal function of each group was assessed by electroretinogram. Concentrations of methanol and formic acid were detected by GC/HS and HPLC, respectively. Results. The a and b amplitudes of methanol treated groups decreased and latent periods delayed in scotopic and photopic ERG recordings...
2016: Journal of Ophthalmology
Xiaotao Yuan, Xin Wang, Xiangye Liu, Hongxin Ge, Guoheng Yin, Chenlong Dong, Fuqiang Huang
One-dimensional nanocrystals favoring efficient charge transfer have attracted enormous attentions, and conductive nanobelts of black titania with a unique band structure and high electrical conductivity would be interestingly used in electrocatalysis. Here, Pd nanodots supported by two kinds of black titania, the oxygen-deficient titania (TiO2-x) and nitrogen-doped titania (TiO2-x:N), were synthesized as efficient composite catalysts for oxygen-reduction reaction (ORR). These composite catalysts show improved catalytic activity with lower overpotential and higher limited current, compared to the Pd nanodots supported on the white titania (Pd/TiO2)...
October 4, 2016: ACS Applied Materials & Interfaces
Lukas Bündgens, Frank Tacke, Christian Trautwein, Alexander Koch
Poisoning with impaired mental state is a frequent cause for hospital admission. The initial management includes assessment of vital functions and airway management followed by focussed diagnostics. Poison Emergency Centers can provide valuable assistance in acute intoxications. Clinically important agents causing mental state alterations include opiates, benzodiazepines, tricyclic antidepressants, alcohol, methanol and ethylene glycol, carbon monoxide and salicylates. Most important therapeutic measures comprise supportive care, decontamination or elimination...
September 2016: Deutsche Medizinische Wochenschrift
Maryam Naseri, Lida Fotouhi, Ali Ehsani, Hamid Mohammad Shiri
In this work, we presented facile route for fabrication of poly ortho aminophenol (POAP) POAP and POAP/ZnO nanocomposite on the surface of the working electrode. The fractal dimension of nanocomposite films in the presence of counter ions was investigated. Surface morphology of the composite film was studied by surface microscopy techniques (SEM). The presence of ZnO in the films was confirmed by EDS analysis. The results indicate that a strong interaction exist at the interface of POAP and nano-ZnO. Different electrochemical methods including galvanostatic charge discharge experiments and cyclic voltammetry have been applied to study the system performance...
December 15, 2016: Journal of Colloid and Interface Science
Daniela Pelclová, Sergey Zakharov
UNLABELLED: Methanol mass poisoning occurs across the world quite frequently, but the complete clinical and laboratory data of the patients are only rarely available. Approximately 138 cases of poisoning were documented in the Czech Republic, 107 patients were hospitalized. Another 31 persons died out of hospital. About 60 % of the hospitalized patients survived intoxication without consequences, one half of the remaining 40 % died and the other half survived with the CNS and/or sight impaired...
2016: Vnitr̆ní Lékar̆ství
V K P Paliwal, R Uniyal, A Azim, Z Neyaz, S N M Muzaffar, A K Baronia
No abstract text is available yet for this article.
September 2016: Anaesthesia and Intensive Care
Paulius Ciegis, Andrejus Zevzikovas, Augusta Zevzikoviene, Palma Nenortiene, Daiva Kazlauskiene
The increasing drug consumption in Lithuania and all over the world makes us think about the negative consequences - the risk of toxicity. Fast and accurate identification of material that caused the poisoning reduces the probability in death cases and makes easier to determine the main cause of death. The results have shown that the most appropriate systems of solvents for qualitative analysis by TLC method of the mixture consisting of alprazolam, codeine and paracetanol are: system "D" (trichloromethane : acetone : conc...
May 2016: Acta Poloniae Pharmaceutica
P F Zabrodskii, V V Maslyakov, M S Gromov
It was established in experiments on noninbred albino rats that the acute intoxication with methanol (1.0 LD50) decreased cellular and humoral immune responses, Th2-lymphocyte activity (to a greater extent as compared to the function of Th1 cells), reduced the blood concentration of immunoregulatory (IFN-g, IL-2, IL-4) and proinflammatory (TNF, IL-1b, IL-6) cytokines on the average by 36.5% (p < 0.05), and did not affect the content of anti-inflammatory cytokines (IL-10, IL-13). Methanol antidote 4-methylpyrazole (non-competitive inhibitor of alcohol dehydrogenase) administered upon acute intoxication with methanol at a dose of 1...
2016: Eksperimental'naia i Klinicheskaia Farmakologiia
Yunus Yildiz, Esma Erken, Handan Pamuk, Hakan Sert, Fatih Sen
Herein, monodisperse platinum (0) nanocatalyst assembled on reduced graphene oxide (Pt(0)@RGO) was easily and reproducibly prepared by the double solvent reduction method at room temperature. Pt(0)@RGO was characterized by X-ray diffraction (XRD), X-ray photoelectron microscopy (XPS) and transmission electron microscopy (TEM) measurements that verify the formation of monodisperse Pt (0) nanoparticles on RGO. The catalytic and electrocatalytic performances of Pt(0) @ RGO in terms of activity, isolability and reusability were investigated for both methanol oxidation and the dehydrocoupling of dimethylamine-borane (DMAB) in which Pt(0)@RGO was found to be highly active and reusable heterogeneous catalyst even at room temperature...
June 2016: Journal of Nanoscience and Nanotechnology
Moonhee Jang, Wonkyung Yang, Sujin Jeong, Sohyung Park, Jihyun Kim
Paramethoxyamphetamine (PMA) is a phenethylamine derivative that is structurally related to 3,4-methylenedioxymethamphetamine (MDMA), but has higher toxicity than MDMA. Here, we report a fatal intoxication case involving PMA. A 36-year-old man was found dead in a hotel room. Toxicological analysis revealed that PMA concentrations were 0.57 and 0.59mg/L in peripheral and heart blood, respectively. Ketamine and diazepam were also detected in his blood. Based on toxicological results and autopsy findings, the cause of death was determined to be acute fatal intoxication with PMA...
September 2016: Forensic Science International
Mary-Margaret A Fill, Donna L Seger, John R Dunn, William Schaffner, Timothy F Jones
In January 2016, the Tennessee Poison Center and Tennessee Department of Health learned of the deaths of two adolescents, and the nonfatal intoxication of two other adolescents, after ingestion of a mixture of racing fuel (approximately 100% methanol) and a carbonated soft drink. The Tennessee Department of Health reviewed medical records and police reports to learn more about the racing fuel source, assess ongoing risk, and guide prevention efforts. These are the first reported deaths in the United States associated with ingestion of this racing fuel mixture...
2016: MMWR. Morbidity and Mortality Weekly Report
Baran Eren, Robert S Weatherup, Nikos Liakakos, Gabor A Somorjai, Miquel Salmeron
Ambient-pressure X-ray photoelectron spectroscopy (APXPS) and high-pressure scanning tunneling microscopy (HPSTM) were used to study the structure and chemistry of model Cu(100) and Cu(111) catalyst surfaces in the adsorption and dissociation of CO2. It was found that the (100) face is more active in dissociating CO2 than the (111) face. Atomic oxygen formed after the dissociation of CO2 poisons the surface by blocking further adsorption of CO2. This "self-poisoning" mechanism explains the need to mix CO into the industrial feed for methanol production from CO2, as it scavenges the chemisorbed O...
July 6, 2016: Journal of the American Chemical Society
Morten Rostrup, Jeffrey K Edwards, Mohamed Abukalish, Masoud Ezzabi, David Some, Helga Ritter, Tom Menge, Ahmed Abdelrahman, Rebecca Rootwelt, Bart Janssens, Kyrre Lind, Raido Paasma, Knut Erik Hovda
[This corrects the article DOI: 10.1371/journal.pone.0152676.].
2016: PloS One
Guangliang Hong, Lufeng Hu, Yahui Tang, Tao Zhang, Xiaowen Kang, Guangju Zhao, Zhongqiu Lu
UNLABELLED: Paraquat (PQ) has caused deaths of numerous people around the world. In order to assess the lethal plasma concentration, the patients who acquired acute PQ intoxication were analyzed by plasma concentration monitoring. The plasma PQ concentrations were determined by high performance liquid chromatography (HPLC) which used 5-bromopyrimidine as internal standard and trichloroacetic acid-methanol (1:9) as protein precipitant. The liver, kidney and coagulation function were determined by automatic biochemical analyzer...
July 2016: Journal of Pharmacological and Toxicological Methods
Sean T Hunt, Maria Milina, Ana C Alba-Rubio, Christopher H Hendon, James A Dumesic, Yuriy Román-Leshkov
We demonstrated the self-assembly of transition metal carbide nanoparticles coated with atomically thin noble metal monolayers by carburizing mixtures of noble metal salts and transition metal oxides encapsulated in removable silica templates. This approach allows for control of the final core-shell architecture, including particle size, monolayer coverage, and heterometallic composition. Carbon-supported Ti(0.1)W(0.9)C nanoparticles coated with Pt or bimetallic PtRu monolayers exhibited enhanced resistance to sintering and CO poisoning, achieving an order of magnitude increase in specific activity over commercial catalysts for methanol electrooxidation after 10,000 cycles...
May 20, 2016: Science
Jongsook Rhee, Hyesun Yum, Sungmin Moon, Sanwhan In, Sangki Lee, Joongseok Seo
Rotenone is a neurotoxin derived from Derris roots or yam bean of genus Derris or Lonchocarpus It is known to cause Parkinson-like symptoms and is a potent electron transport inhibitor. Rotenone was detected in postmortem specimens in a fatal case of rotenone poisoning with an organic pesticide by liquid chromatography-tandem mass spectrometry with an information-dependent acquisition and MS-MS library search. The forensic specimens were prepared by solid-phase extraction with a Bond Elut(®) Certify cartridge...
July 2016: Journal of Analytical Toxicology
Jeffrey A Kraut
Methanol intoxication is an uncommon but serious poisoning. Its adverse effects are due primarily to the impact of its major metabolite formic acid and lactic acid resulting from cellular hypoxia. Symptoms including abdominal pain and loss of vision can appear a few hours to a few days after exposure, reflecting the time necessary for accumulation of the toxic byproducts. In addition to a history of exposure, increases in serum osmolal and anion gaps can be clues to its presence. However, increments in both parameters can be absent depending on the nature of the toxic alcohol, time of exposure, and coingestion of ethanol...
July 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
Jilei Liu, Felicia R Lucci, Ming Yang, Sungsik Lee, Matthew D Marcinkowski, Andrew J Therrien, Christopher T Williams, E Charles H Sykes, Maria Flytzani-Stephanopoulos
Platinum catalysts are extensively used in the chemical industry and as electrocatalysts in fuel cells. Pt is notorious for its sensitivity to poisoning by strong CO adsorption. Here we demonstrate that the single-atom alloy (SAA) strategy applied to Pt reduces the binding strength of CO while maintaining catalytic performance. By using surface sensitive studies, we determined the binding strength of CO to different Pt ensembles, and this in turn guided the preparation of PtCu alloy nanoparticles (NPs). The atomic ratio Pt:Cu = 1:125 yielded a SAA which exhibited excellent CO tolerance in H2 activation, the key elementary step for hydrogenation and hydrogen electro-oxidation...
May 25, 2016: Journal of the American Chemical Society
Jin-xiao Zhai, Wei Liu
OBJECTIVE: To determinate triptolide and wilforlide A in biological samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS) method and to verify the method. METHODS: After 0.4 mL blood, urine or 0.4 g hepatic tissues with internal standard were extracted by ethyl acetate, they were separated on a Allure PFP Propyl (100 mm x 2.1 mm, 5 µm) with a mobile phase of methanol-20 mmol/L ammonium acetate using gradient elution. For mass spectrometric detection, electrospray ionization (ESI⁺) in positive mode was elected and the data was collected using multiple-reaction monitoring (MRM)...
December 2015: Fa Yi Xue za Zhi
Vinod Kumar Puthiyapura, Dan J L Brett, Andrea E Russell, Wen-Feng Lin, Christopher Hardacre
Direct alcohol fuel cells (DAFCs) mostly use low molecular weight alcohols such as methanol and ethanol as fuels. However, short-chain alcohol molecules have a relative high membrane crossover rate in DAFCs and a low energy density. Long chain alcohols such as butanol have a higher energy density, as well as a lower membrane crossover rate compared to methanol and ethanol. Although a significant number of studies have been dedicated to low molecular weight alcohols in DAFCs, very few studies are available for longer chain alcohols such as butanol...
May 25, 2016: ACS Applied Materials & Interfaces
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"