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https://www.readbyqxmd.com/read/28628271/surgical-treatment-of-trans-sphincteric-anal-fistulas-with-the-fat-graft-technique-a-minimally-invasive-procedure
#1
N Stroumza, G Fuzco, J Laporte, R Nail Barthelemy, S Houry, M Atlan
AIM: Anal fistulas are common pathologies with a significant social impact; however their treatment is often complex and the recurrence rate can be significant. Some surgical treatments for fistula are also associated with the risk of sphincter injury. In this technical note, we aim to evaluate the feasibility and efficacy of the Fat GRAFT technique (Fat Grafting in Anal Fistula Treatment) in the treatment of recurrent anal fistulas. METHOD: All patients presenting with recurrent trans-sphincteric anal fistulas over an 18-month period were included...
June 19, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28615491/enhanced-osteointegration-of-poly-methylmethacrylate-bone-cements-by-incorporating-strontium-containing-borate-bioactive-glass
#2
Xu Cui, Chengcheng Huang, Meng Zhang, Changshun Ruan, Songlin Peng, Li Li, Wenlong Liu, Ting Wang, Bing Li, Wenhai Huang, Mohamed N Rahaman, William W Lu, Haobo Pan
Although poly(methylmethacrylate) (PMMA) cements are widely used in orthopaedics, they have numerous drawbacks. This study aimed to improve their bioactivity and osseointegration by incorporating strontium-containing borate bioactive glass (SrBG) as the reinforcement phase and bioactive filler of PMMA cement. The prepared SrBG/PMMA composite cements showed significantly decreased polymerization temperature when compared with PMMA and retained properties of appropriate setting time and high mechanical strength...
June 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28606448/platelet-transfusion-in-thrombocytopenic-cancer-patients-sometimes-justified-but-likely-insidious
#3
REVIEW
Thierry Burnouf, Mohamed Elemary, Julia Radosevic, Jerard Seghatchian, Hadi Goubran
The transfusion of platelet concentrates prepared from allogeneic single or pooled donations is a standard procedure in transfusion medicine to stop or prevent bleeding in cancer patients with thrombocytopenia undergoing surgery, chemotherapy and/or radiotherapy. While platelet transfusion may appear reasonable in many instances, greater scientific and medical attention should however be given to the possibly insidious impact of transfused platelets on the outcome of cancers. Indeed platelets and the microvesicles they release possess all the biological ingredients capable of supporting tumor growth, protecting circulating tumor cells, and to contributing to metastatic invasion...
May 26, 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/28603651/endobronchial-ultrasound-guided-transbronchial-needle-aspiration-ebus-tbna-from-morphology-to-molecular-testing
#4
REVIEW
Luisella Righi, Francesca Franzi, Francesca Montarolo, Gaia Gatti, Massimo Bongiovanni, Fausto Sessa, Stefano La Rosa
In recent years, endobronchial ultrasound-guided TBNA (EBUS-TBNA) has emerged as an innovative technique for diagnosis and staging of lung cancer and has been successfully introduced into daily clinical practice with several advantages including minimally invasive approach, safe, cost-effective, real time image guidance, broad sampling capability, and rapid on-site evaluation (ROSE). Both cytological and histological approach could be useful to have material for diagnosis, immunohistochemical and molecular analyses which may be very important for targeted therapy with successful rate ranging from 89% to 98%...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28599179/a-needle-type-glucose-biosensor-based-on-pani-nanofibers-and-pu-e-pu-membrane-for-long-term-invasive-continuous-monitoring
#5
Lu Fang, Bo Liang, Guang Yang, Yichuan Hu, Qin Zhu, Xuesong Ye
A minimally invasive glucose biosensor capable of continuous monitoring of subcutaneous glucose has been developed in this study. This sensor was prepared using electropolymerized conductive polymer polyaniline (PANI) nanofibers as an enzyme immobilization material and polyurethane (PU)/epoxy-enhanced polyurethane (E-PU) bilayer coating as a protective membrane. The sensor showed almost the same sensitivity (63nA/mM) and linearity (0-20mM with the correlation coefficient r(2) of 0.9997) in both PBS and bovine serum tests...
April 28, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28587738/important-non-technical-skills-in-video-assisted-thoracoscopic-surgery-lobectomy-team-perspectives
#6
Kirsten Gjeraa, Anna S Mundt, Lene Spanager, Henrik J Hansen, Lars Konge, René H Petersen, Doris Østergaard
BACKGROUND: Safety in the operating room is dependent on the team's non-technical skills. The importance of non-technical skills appears to be different for minimally invasive surgery as compared with open surgery. The aim of this study was to identify which non-technical skills are perceived by team members to be most important for patient safety, in the setting of video-assisted thoracoscopic surgery (VATS) lobectomy. METHODS: This was an explorative, semistructured interview-based study with 21 participants from all four thoracic surgery centers in Denmark that perform VATS lobectomy...
July 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28584674/injectable-hydrogels-for-cartilage-and-bone-tissue-engineering
#7
REVIEW
Mei Liu, Xin Zeng, Chao Ma, Huan Yi, Zeeshan Ali, Xianbo Mou, Song Li, Yan Deng, Nongyue He
Tissue engineering has become a promising strategy for repairing damaged cartilage and bone tissue. Among the scaffolds for tissue-engineering applications, injectable hydrogels have demonstrated great potential for use as three-dimensional cell culture scaffolds in cartilage and bone tissue engineering, owing to their high water content, similarity to the natural extracellular matrix (ECM), porous framework for cell transplantation and proliferation, minimal invasive properties, and ability to match irregular defects...
2017: Bone Research
https://www.readbyqxmd.com/read/28583902/ph-responsive-self-healing-injectable-hydrogel-based-on-n-carboxyethyl-chitosan-for-hepatocellular-carcinoma-therapy
#8
Jin Qu, Xin Zhao, Peter X Ma, Baolin Guo
Injectable hydrogels with pH-responsiveness and self-healing ability have great potential for anti-cancer drug delivery. Herein, we developed a series of polysaccharide-based self-healing hydrogels with pH-sensitivity as drug delivery vehicles for hepatocellular carcinoma therapy. The hydrogels were prepared by using N-carboxyethyl chitosan (CEC) synthesized via Michael reaction in aqueous solution and dibenzaldehyde-terminated poly(ethylene glycol) (PEGDA). Doxorubicin (Dox), as a model of water-soluble small molecule anti-cancer drug was encapsulated into the hydrogel in situ...
June 2, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28581195/minimal-preparation-ct-a-literature-review-of-a-minimally-invasive-imaging-technique-for-colorectal-cancer-in-a-frail-aged-population
#9
REVIEW
Andrew D Csillag, Anna R Quirk, Michael V Chan, Lloyd J Ridley
Colorectal cancer (CRC) is a common malignancy with increased incidence in the elderly. When CRC is suspected, patients are typically evaluated with optical colonoscopy (OC) or CT Colonography (CTC). Unfortunately, in the frail and elderly patient, these investigations can be difficult to perform and are often not tolerated. Minimal preparation computed tomography (MPCT) is a CT technique to evaluate the colon. Although protocols vary, typically, no preparation is required apart from administration of oral contrast for faecal tagging...
June 5, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/28580716/preparation-and-characterization-of-injectable-pmma-strontium-substituted-bioactive-glass-bone-cement-composites
#10
I Goñi, R Rodríguez, I García-Arnáez, J Parra, M Gurruchaga
In most minimally-invasive procedures used to address severe pain arising from compression fractures of the vertebral bodies, such as percutaneous vertebroplasty (PVP), a poly(methyl methacrylate) (PMMA) bone cement is used. Shortcomings of this type of cement, such as high exotherm temperature and lack of bioactivity, are well known. We prepared different formulations of a composite bone cement, whose solid constituents consisted of PMMA beads and particles of a bioactive glass (BG), where 0-20%(w/w) of the calcium component was substituted by strontium...
June 5, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28571262/evaluation-of-microleakage-with-total-etch-self-etch-and-universal-adhesive-systems-in-class-v-restorations-an-in-vitro-study
#11
Anjali Gupta, Pradeep Tavane, Pankaj Kumar Gupta, Bellam Tejolatha, Ashik Ali Lakhani, Ram Tiwari, Shruti Kashyap, Gaurav Garg
INTRODUCTION: Adhesive dentistry is overwhelmingly evolving with respect to the dental surgeon's and patient's perspective. Embracing the concept of minimally invasive dentistry which follows minimum intervention performed to produce good adhesion and tooth coloured restoration, in turn makes the newer generation bonding agents more acceptable and appropriate withstanding the demand for stable restoration. AIM: To study and compare the extent of microleakage between tooth and restoration interface in class V composite resin restorations applying one Total Etch (Adper(TM) single bond), two Self Etch (Adper(TM) SE Plus, Adper(TM) Easy One) and Universal bonding agents using dye penetration method...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28567382/where-do-i-see-minimally-invasive-endoscopy-in-2020-clock-is-ticking
#12
REVIEW
Rami Eliakim
Since it was introduced 17 years ago, capsule endoscopy has become an important diagnostic tool for the small bowel. Three generations of the original small bowel capsule have been developed since (PillCam SB3, Medtronic, USA), and four competitors were introduced for the small bowel. A non-video patency capsule (Agile patency capsule, Medtronic, USA) was also developed, in order to confirm patency and thus avoid retention in the GI tract. Moreover, capsules viewing other organs of the body (esophagus, colon) as well as three different magnetic guided capsules that visualize the stomach as good as optical endoscopy (OE) have been developed...
May 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28544808/the-first-transepidermal-transplantation-of-non-cultured-epidermal-suspension-using-a-dermarolling-system-in-vitiligo-a-sequential-histological-and-clinical-study
#13
L Benzekri, Y Gauthier
The current methods for melanocyte delivery to depigmented skin are invasive and often require sophisticated approaches. Here we describe a promising simple and minimally invasive technique based on the dermarolling system. The technique involves preparation of a keratinocyte/melanocyte suspension prepared by trypsinization from a non-lesioned part of a patient's scalp skin and transepidermal delivery using a dermaroller equipped with 0.2 mm needles. Dermarolling leads to epidermal microinjuries without, however, causing pain or inflammation...
May 19, 2017: Pigment Cell & Melanoma Research
https://www.readbyqxmd.com/read/28540810/minimally-invasive-local-ablative-therapies-in-combination-with-radioiodine-therapy-in-benign-thyroid-disease-preparation-feasibility-and-efficiency-preliminary-results
#14
Alexander Mader, Oscar Maximilian Mader, Daniel Gröner, Yücel Korkusuz, Shadi Ahmad, Frank Grünwald, W Tilman Kranert, Christian Happel
PURPOSE: Initial studies of combinations of radioiodine therapy (RIT) and local ablative procedures for the treatment of thyroid nodules have shown promising results. The goal of this study was to evaluate the effectiveness of RIT combined with radiofrequency ablation (RFA) in patients with goitres and to determine which ablative procedure is the most suitable for a combined therapy. METHODS: Thirty patients with goitres were divided into two subgroups. A test group of 15 patients received combined therapy (RIT + RFA) and a control group of 15 patients received RIT mono therapy...
May 5, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28516050/towards-mri-temperature-mapping-in-real-time-the-proton-resonance-frequency-method-with-undersampled-radial-mri-and-nonlinear-inverse-reconstruction
#15
Zhongshuai Zhang, Thomas Michaelis, Jens Frahm
BACKGROUND: Optimal control of minimally invasive interventions by hyperthermia requires dynamic temperature mapping at high temporal resolution. METHODS: Based on the temperature-dependent shift of the proton resonance frequency (PRF), this work developed a method for real-time MRI thermometry which relies on highly undersampled radial FLASH MRI sequences with iterative image reconstruction by regularized nonlinear inversion (NLINV). As a first step, the method was validated with use of a temperature phantom and ex vivo organs (swine kidney) subjected to heating by warm water or a pulsed laser source...
April 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28513319/effect-of-surface-functionalizations-of-multi-walled-carbon-nanotubes-on-neoplastic-transformation-potential-in-primary-human-lung-epithelial-cells
#16
Todd A Stueckle, Donna C Davidson, Ray Derk, Peng Wang, Sherri Friend, Diane Schwegler-Berry, Peng Zheng, Nianqiang Wu, Vince Castranova, Yon Rojanasakul, Liying Wang
Functionalized multi-walled carbon nanotube (fMWCNT) development has been intensified to improve their surface activity for numerous applications, and potentially reduce toxic effects. Although MWCNT exposures are associated with lung tumorigenesis in vivo, adverse responses associated with exposure to different fMWCNTs in human lung epithelium are presently unknown. This study hypothesized that different plasma-coating functional groups determine MWCNT neoplastic transformation potential. Using our established model, human primary small airway epithelial cells (pSAECs) were continuously exposed for 8 and 12 weeks at 0...
June 2, 2017: Nanotoxicology
https://www.readbyqxmd.com/read/28507426/performance-of-high-school-students-in-a-laparoscopic-training-program
#17
Scott Furer, Sarah Alam, James Rosser
BACKGROUND AND OBJECTIVES: We hypothesized that high school students can be subjected to the same laparoscopic surgical training curriculum used by surgeons and successfully complete it. The goal of this study was to evaluate the appropriateness of early training in minimally invasive surgical techniques. METHODS: Thirteen high school students, ages 15-18, participated in the validated Top Gun Surgeon Laparoscopic Skills and Suturing program. The students performed 3 preparatory drills 10 times each...
April 2017: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/28486354/minimally-invasive-approach-based-on-pterygoid-and-short-implants-for-rehabilitation-of-an-extremely-atrophic-maxilla-case-report
#18
Alessandro Cucchi, Elisabetta Vignudelli, Simonetta Franco, Giuseppe Corinaldesi
INTRODUCTION: Extremely atrophic maxillae can be considered the most important indication for three-dimensional maxillary reconstruction. Different bone-augmentation techniques have been suggested to accomplish this. This article illustrates a minimally invasive approach to rehabilitation of the extremely atrophic maxilla. MATERIAL AND METHODS: A 63-year-old male patient was referred for restoration of his totally edentulous maxilla with a fixed full-arch implant-prosthetic rehabilitation...
May 8, 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28464571/-expert-consensus-of-laparoscopic-pancreaticoduodenectomy-postscript-of-operation-process-and-main-steps
#19
(no author information available yet)
Laparoscopic pancreaticoduodenectomy (LPD) is a minimally invasive approach for Whipple by total or assistant laparoscopic techniques. The results of feasibility, safety, short and long outcomes have slowly been gaining acceptance over the past decade. Aim to further adapt to the development trend, improve the safety and oncologic outcomes, promote the standardized development of LPD in China, four pancreas surgery groups in China wrote this LPD consensus. The consensus includes seven sections: operator request, indications and contraindications, preoperative preparation and anesthesia, equipment and instruments, positioning of patient and trocars, abdominal pressure, indications of conversion to laparotomy, postoperative observation and treatment...
May 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28456557/no-post-no-core-approach-to-restore-severely-damaged-posterior-teeth-an-up-to-10-year-retrospective-study-of-documented-endocrown-cases
#20
Marcia M Belleflamme, Sabine O Geerts, Marie M Louwette, Charlotte F Grenade, Alain J Vanheusden, Amélie K Mainjot
OBJECTIVES: The objectives of the present study were to (1) retrospectively evaluate documented cases of ceramic and composite endocrowns performed using immediate dentin sealing (IDS); (2) correlate failures with clinical parameters such as tooth preparation characteristics and occlusal parameters. METHODS: 99 documented cases of endocrowns were evaluated after a mean observation period of 44.7±34.6months. A classification of restorations was established in function of the level of damage of residual tooth tissues after preparation, from 1 to 3...
April 27, 2017: Journal of Dentistry
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