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Minimally invasive preparation

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https://www.readbyqxmd.com/read/29667041/perception-versus-reality-elucidating-motivation-and-expectations-of-current-fellowship-council-minimally-invasive-surgery-fellows
#1
Jeffrey R Watkins, Aurora D Pryor, Michael S Truitt, D Rohan Jeyarajah
BACKGROUND: The aim of our study is to determine minimally invasive trainee motivation and expectations for their respective fellowship. Minimally Invasive Surgery (MIS) is one of the largest non-ACGME post-residency training pathways though little is known concerning the process of residents choosing MIS as a fellowship focus. As general surgery evolves, it is important to understand resident motivation in order to better prepare them for a surgical career. METHODS: A survey invitation was sent to current trainees in the Minimally Invasive and related pathways through the Fellowship Council...
April 17, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29660407/application-of-water-soluble-polyvinyl-alcohol-based-film-patches-on-laser-microporated-skin-facilitates-intradermal-macromolecule-and-nanoparticle-delivery
#2
Laura Engelke, Gerhard Winter, Julia Engert
The intradermal delivery of biologics has long been recognized as attractive approach for cutaneous immunotherapy, particularly vaccination. Although intradermal (i.d.) or subcutaneous (s.c.) injection provide reproducible dosing and good cost- and delivery efficiency, the major objective to avoid sharps and the need for enhanced storage stability have renewed the interest in alternative needle-free delivery strategies. This study presents a new concept for the delivery of macromolecules and nanoparticles to viable skin layers with a high density of professional antigen-presenting cells (APCs)...
April 13, 2018: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/29649332/development-of-novel-est-ssr-markers-for-ploidy-identification-based-on-de-novo-transcriptome-assembly-for-misgurnus-anguillicaudatus
#3
Bing Feng, Soojin V Yi, Manman Zhang, Xiaoyun Zhou
The co-existence of several ploidy types in natural populations makes the cyprinid loach Misgurnus anguillicaudatus an exciting model system to study the genetic and phenotypic consequences of ploidy variations. A first step in such effort is to identify the specific ploidy of an individual. Currently popular methods of karyotyping via cytological preparation or flow cytometry require a large amount of tissue (such as blood) samples, which can be damaging or fatal to the fishes. Here, we developed novel microsatellite markers (SSR markers) from M...
2018: PloS One
https://www.readbyqxmd.com/read/29648413/joint-consensus-on-abdominal-robotic-surgery-and-anaesthesia-from-a-task-force-of-the-siaarti-and-sic
#4
Antonio Corcione, Pierluigi Angelini, Lapo Bencini, Elisabetta Bertellini, Felice Borghi, Claudio Buccelli, Giuseppe Coletta, Clelia Esposito, Vincenzo Graziano, Fabio Guarracino, Domenico Marchi, Pasquale Misitano, Anna M Mori, Mariano Paternoster, Vincenzo Pennestrì, Vittorio Perrone, Luigi Pugliese, Stefano Romagnoli, Luigia Scudeller, Francesco Corcione
BACKGROUND: Minimally invasive surgical procedures have revolutionized the world of surgery in the past decades. While laparoscopy, the first minimally invasive surgical technique to be developed, is widely used and has been addressed by several guidelines and recommendations, the implementation of robotic-assisted surgery is still hindered by the lack of consensus documents that support healthcare professionals in the management of this novel surgical procedure. Here we summarize the available evidence and provide expert opinion aimed at improving the implementation and resolution of issues derived from robotic abdominal surgery procedures...
April 12, 2018: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29629197/enhanced-recovery-after-thoracic-surgery-patient-information-and-care-plans
#5
REVIEW
Majed Refai, Marco Andolfi, Paolo Gentili, Gilda Pelusi, Francesca Manzotti, Armando Sabbatini
Many studies have confirmed that the implementation of enhanced recovery after surgery (ERAS) protocols has the advantages of reducing the potential complications after thoracic surgery and the length of hospital stay. The ERAS program involves a multidisciplinary team, aimed at integrating evidence-based knowledge into clinical practice in order to reduce the patient's stress response to the surgical procedure and improve the response to stress, guaranteeing a combination of better outcomes and cost savings...
March 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29600867/minimally-invasive-ceramic-restorations-a-step-by-step-clinical-approach
#6
Carlos Marcelo Archangelo, José Carlos Romanini, Karen Cristina Archangelo, Isis Almela Endo Hoshino, Rodolfo Bruniera Anchieta
Minimally invasive treatments are a dominant trend in dentistry. Due to the evolution of adhesive materials and ceramics, minimalistic ceramic restorations have been proposed as alternative treatment options to avoid unnecessary tooth reduction. The aim of this article is to show a clinical protocol for the correct diagnosis, treatment planning, and execution of minimally invasive ceramic veneers. Requiring only slight tooth preparation, this conservative technique is well-suited for restoration of teeth that need color and shape modification...
April 2018: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/29589456/-laparoscopy-at-the-pediatric-surgery-department-for-a-five-year-period
#7
D Starý, J Tůma, R Doušek, R Macháček, J Škvařil, L Plánka
INTRODUCTION: Laparoscopy in small children was developed only after the adoption and verification of basic principles in adult patients and is mostly concentrated in specialized facilities due to the possible complications and necessity of follow-up specialized anesthesiological and post-operative care. In the 1990s, the Clinic of Paediatric Surgery, Orthopaedics and Traumatology at University Hospital Brno was one of the first in the Czech Republic to begin operating on children laparoscopically...
2018: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/29587193/development-of-cu-nanoflowers-modified-the-flexible-needle-type-microelectrode-and-its-application-in-continuous-monitoring-glucose-in-vivo
#8
Yuxin Fang, Shenjun Wang, Yangyang Liu, Zhifang Xu, Kuo Zhang, Yi Guo
A minimally invasive glucose microbiosensor based the flexibly integrated electrode for continuous monitoring glucose in vivo has been developed in this study. This was achieved by coating needle-type microelectrode with Cu nanoflowers, nafion, glucose oxidase (GOD) and polyurethane (PU) membranes, successfully prepared with layer-by-layer deposition. The Cu nanomaterials provided a large specific surface area and electrocatalytic activity for glucose detection. The PU layers as mass-transport limiting membranes significantly enhanced the linearity and stability of sensors...
March 13, 2018: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29575752/rapid-on-site-evaluation-using-telecytology-a-major-cancer-center-experience
#9
Oscar Lin, Dorota Rudomina, Rusmir Feratovic, S Joseph Sirintrapun
BACKGROUND: Rapid on-site evaluation (ROSE) with cytology preparations plays a critical role in minimally invasive procedures. The time spent by a pathologist performing ROSE is unpredictable and could be used for more cost-effective activities. The solution encountered by several institutions to address this issue is the use of telecytology (TC). This study analyzes the experience of using telecytology for ROSE in a major cancer center over a period of over 2 years. METHODS: A retrospective analysis of all remote TC evaluations for adequacy on fine needle aspiration (FNA) and touch preparations (TP) of core biopsies (CB) performed at a major cancer center was performed...
March 25, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29575423/cytological-preparations-for-molecular-analysis-a-review-of-technical-procedures-advantages-and-limitations-for-referring-samples-for-testing
#10
REVIEW
G da Cunha Santos, M A Saieg, G Troncone, P Zeppa
Minimally invasive procedures such as endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) must yield not only good quality and quantity of material for morphological assessment, but also an adequate sample for analysis of molecular markers to guide patients to appropriate targeted therapies. In this context, cytopathologists worldwide should be familiar with minimum requirements for refereeing cytological samples for testing. The present manuscript is a review with comprehensive description of the content of the workshop entitled Cytological preparations for molecular analysis: pre-analytical issues for EBUS TBNA, presented at the 40th European Congress of Cytopathology in Liverpool, UK...
April 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29563163/anti-htert-sirna-loaded-nanoparticles-block-the-growth-of-anaplastic-thyroid-cancer-xenograft
#11
Giovanni E Lombardo, Valentina Maggisano, Marilena Celano, Donato Cosco, Chiara Mignogna, Federica Baldan, Saverio M Lepore, Lorenzo Allegri, Sonia Moretti, Cosimo Durante, Giuseppe Damante, Massimo Fresta, Diego Russo, Stefania Bulotta, Efisio Puxeddu
The high frequency of hTERT-promoting mutations and the increased expression of hTERT mRNA in anaplastic thyroid cancer (ATC) make TERT a suitable molecular target for the treatment of this lethal neoplasm. In this study, we encapsulated an anti-hTERT oligonucleotide in biocompatible nanoparticles and analyzed the effects of this novel pharmaceutical preparation in preclinical models of ATC. Biocompatible nanoparticles were obtained in an acidified aqueous solution containing chitosan, anti-hTERT oligoRNAs and poloxamer 188 as a stabilizer...
March 21, 2018: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/29558567/operating-list-composition-and-surgical-performance
#12
T W Pike, F Mushtaq, R P Mann, P Chambers, G Hall, J E Tomlinson, R Mir, R M Wilkie, M Mon-Williams, J P A Lodge
BACKGROUND: Recent reviews suggest that the way in which surgeons prepare for a procedure (warm up) can affect performance. Operating lists present a natural experiment to explore this phenomenon. The aim was to use a routinely collected large data set on surgical procedures to understand the relationship between case list order and operative performance. METHOD: Theatre lists involving the 35 procedures performed most frequently by senior surgeons across 38 private hospitals in the UK over 26 months were examined...
March 20, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29555096/cellular-differentiation-bioactive-and-mechanical-properties-of-experimental-light-curing-pulp-protection-materials
#13
Salvatore Sauro, Ashvin Babbar, Borzo Gharibi, Victor Pinheiro Feitosa, Ricardo Marins Carvalho, Lidiany Karla Azevedo Rodrigues, Avijit Banerjee, Timothy Watson
OBJECTIVE: Materials for pulp protection should have therapeutic properties in order to stimulate remineralization and pulp reparative processes. The aim of this study was to evaluate the mechanical properties, biocompatibility, cell differentiation and bioactivity of experimental light-curable resin-based materials containing bioactive micro-fillers. METHODS: Four calcium-phosphosilicate micro-fillers were prepared and incorporated into a resin blend: 1) Bioglass 45S5 (BAG); 2) zinc-doped bioglass (BAG-Zn); 3) βTCP-modified calcium silicate (β-CS); 4) zinc-doped β-CS (β-CS-Zn)...
March 16, 2018: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/29552510/intraoperative-complications-during-vats-lobectomies-from-conversion-to-minimally-invasive-trouble-shooting
#14
Paolo Lucciarini, Florian Augustin, Herbert Thomas Maier, Francesco Zaraca, Thomas Schmid
The aim of this study was to explore intraoperative complications during video-assisted thoracoscopic surgery (VATS) lobectomy. Vascular and bronchial injuries, after a robust learning curve, can be sometimes successfully managed by VATS. During a VATS lobectomy, it is necessary: to be prepared in potentially dangerous situations; to think about strategies to handle intraoperative complications and to share these strategies with your own staff. Herein we present some videos showing cases where vascular injuries led to conversion and others where a minimally-invasive trouble shooting of intraoperative complications was achieved...
2018: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/29548357/patient-engagement-to-enhance-recovery-for-children-undergoing-surgery
#15
Kurt F Heiss, Mehul V Raval
For over 20 years enhanced recovery protocols (ERPs) have been used to decrease the physiologic stress and inflammation of surgery using evidence-based principles. ERPs include optimizing patient preparation, creating less trauma using minimally invasive anesthetic and surgical techniques, and regular audit of outcomes. A critical aspect of ERPs is patient engagement in all phases of care, which facilitates effective team function and focused oversight of patient flow through the system. Counseling extends beyond traditional review of surgical risks and benefits, by creating clear daily patient goals, establishing pain management plans, optimizing nutrition, and defining criteria for discharge...
April 2018: Seminars in Pediatric Surgery
https://www.readbyqxmd.com/read/29547001/molecular-pathology-of-lung-cancer-cytology-specimens-a-concise-review
#16
Deepali Jain, Sinchita Roy-Chowdhuri
CONTEXT: - There has been a paradigm shift in the understanding of molecular pathogenesis of lung cancer. A number of oncogenic drivers have been identified in non-small cell lung carcinoma, such as the epidermal growth factor receptor ( EGFR) mutation and anaplastic lymphoma kinase ( ALK) gene rearrangement. Because of the clinical presentation at an advanced stage of disease in non-small cell lung carcinoma patients, the use of minimally invasive techniques is preferred to obtain a tumor sample for diagnosis...
March 16, 2018: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/29527396/how-to-perform-the-wiltse-posterolateral-spinal-approach-technical-note
#17
A Guiroy, A Sícoli, N Gonzalez Masanés, A Morales Ciancio, M Gagliardi, A Falavigna
Background: The paraspinal, posterolateral, or Wiltse approach is an old technique that observes the principles of an MIS procedure. The aim of this study was to provide a step-by-step description from the literature of the Wiltse paraspinal approach and analyze its main advantages and limitations. Methods: Here, we provide a step-by-step description of the Wiltse approach. Utilizing PubMed and Lilacs and the Mesh terms "Wiltse approach," "paraspinal approach," "muscle sparing approach," and "lumbar spine," we identified 10 papers...
2018: Surgical Neurology International
https://www.readbyqxmd.com/read/29527141/reproducible-proteomics-sample-preparation-for-single-ffpe-tissue-slices-using-acid-labile-surfactant-and-direct-trypsinization
#18
Melanie Christine Föll, Matthias Fahrner, Victor Oginga Oria, Markus Kühs, Martin Lothar Biniossek, Martin Werner, Peter Bronsert, Oliver Schilling
Background: Proteomic analyses of clinical specimens often rely on human tissues preserved through formalin-fixation and paraffin embedding (FFPE). Minimal sample consumption is the key to preserve the integrity of pathological archives but also to deal with minimal invasive core biopsies. This has been achieved by using the acid-labile surfactant RapiGest in combination with a direct trypsinization (DTR) strategy. A critical comparison of the DTR protocol with the most commonly used filter aided sample preparation (FASP) protocol is lacking...
2018: Clinical Proteomics
https://www.readbyqxmd.com/read/29516952/expert-consensus-statement-on-computed-tomography-guided-125-i-radioactive-seeds-permanent-interstitial-brachytherapy
#19
REVIEW
Junjie Wang, Shude Chai, Guangjun Zheng, Yuliang Jiang, Zhe Ji, Fuxin Guo, Hongqing Zhuang, Kaixian Zhang
The aim of this study is to develop expert consensus statement for recommendations of patient selection criteria, prescription dose, and procedure of computed tomography (CT)-guided125 I radioactive seeds permanent interstitial brachytherapy. Members of Chinese medical association radiation oncology branch, Chinese medical association radiation therapy professional committee, Chinese cancer society minimally invasive surgery branch seed therapy group, Chinese geriatric cancer society minimally invasive surgery branch, Beijing medical association radiation oncology professional committee, China northern radioactive seeds brachytherapy group formed a committee, which consists of physician members who come from the department of radiation oncology, surgery, intervention, internal medicine, ultrasound, and nuclear medicine...
January 2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29492908/-clinical-research-status-of-laparoscopic-gastric-cancer-surgery-in-china-japan-and-south-korea
#20
Guoxin Li, Xinhua Chen, Jiang Yu, Hao Liu
Laparoscopic surgery has its unique minimally invasive advantages, however, taking the complex and difficult D2 lymph node dissection for advanced gastric cancer into consideration, laparoscopic gastrectomy was only applied in the treatment of early gastric cancer at its preliminary stage. With the development of more than a decade, many multicenter clinical data have confirmed the safety, feasibility and effectiveness of laparoscopic radical gastrectomy for early gastric cancer. Based on high-quality evidence-based medicine evidence, laparoscopic gastrectomy has been recommended as an optional treatment for stage I( gastric cancer by the Japanese Gastric Cancer Treatment Guidelines 2014(ver...
February 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
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