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https://www.readbyqxmd.com/read/29223059/a-highly-selective-fluorescence-sensing-platform-for-nanomolar-hg-ii-detection-based-on-cytosine-derived-quantum-dot
#1
Liang Luo, Ting Song, Haoqiang Wang, Qunhui Yuan, Shenghai Zhou
Inspired by low toxicity and good biocompatibility of biomass derived quantum dot (QD), we herein developed a cytosine derived quantum dot, namely cyt-dot, via a one-step hydrothermal synthesis. The as-prepared cyt-dot emits blue fluorescence (FL) containing abundant oxygen (20.6at.%) and nitrogen (24.1at.%) contents. The cyt-dot based sensing platform shows exclusive selectivity for Hg(II) while being insensitive towards Fe(III) and Ag(I), which are important interference that usually cannot be ruled out. The detection limit for Hg(II) is of 11nM, which is very close to the guideline value of 10nM allowed by the U...
November 22, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29223038/polymer-matrix-of-fiber-reinforced-composites-changes-in-the-semi-interpenetrating-polymer-network-during-the-shelf-life
#2
Aftab A Khan, Abdulaziz A Al-Kheraif, Abdullah M Al-Shehri, Eija Säilynoja, Pekka K Vallittu
This laboratory study was aimed to characterize semi-interpenetrating polymer network (semi-IPN) of fiber-reinforced composite (FRC) prepregs that had been stored for up to two years before curing. Resin impregnated prepregs of everStick C&B (StickTech-GC, Turku, Finland) glass FRC were stored at 4°C for various lengths of time, i.e., two-weeks, 6-months and 2-years. Five samples from each time group were prepared with a light initiated free radical polymerization method, which were embedded to its long axis in self-curing acrylic...
November 26, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29222983/the-action-is-in-the-task-set-not-in-the-action
#3
Maria M Robinson, John Clevenger, David E Irwin
In 7 experiments we contrasted two accounts for novel sources of attentional bias. According to the action-based account, executing a motor response towards an object causes people to allocate attention preferentially towards properties of that object in a subsequent task even when properties of the acted-on object are task irrelevant. This remarkable view entails that motor processing is in itself sufficient to affect later attentional processing, in the absence of stimulus evaluation and motor preparation...
December 6, 2017: Cognitive Psychology
https://www.readbyqxmd.com/read/29222981/fabrication-of-biocompatible-and-efficient-antimicrobial-porous-polymer-surfaces-by-the-breath-figures-approach
#4
Nelson Vargas-Alfredo, Enrique Martínez-Campos, Ana Santos-Coquillat, Ane Dorronsoro, Aitziber L Cortajarena, Adolfo Del Campo, Juan Rodríguez-Hernández
We designed and fabricated highly efficient and selective antibacterial substrates, i.e. surface non-cytotoxic against mammalian cells but exhibiting strong antibacterial activity. For that purpose, microporous substrates (pore sizes in the range of 3-5 μm) were fabricated using the Breath Figures approach (BFs). These substrates have additionally a defined chemical composition in the pore cavity (herein either a poly(acrylic acid) or the antimicrobial peptide Nisin) while the composition of the rest of the surface is identical to the polymer matrix...
November 20, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29222654/determination-of-total-phthalate-in-cosmetics-using-a-simple-three-phase-sample-preparation-method
#5
Laping Liu, Zhengmeng Wang, Sihan Zhao, Jiahui Duan, Hu Tao, Wenji Wang, Shuhui Liu
A simple sample preparation method requiring minimal organic solvents is proposed for the determination of the total phthalate content in cosmetics by high-performance liquid chromatography-tandem mass spectrometry. The hydrolysis of phthalates and purification of interfering substances were performed in a three-phase system that included an upper n-hexane phase, a middle ethanol phase, and a lower aqueous alkali solution. This three-phase system utilized an incremental purification strategy. The apolar ingredients were extracted with n-hexane, the polar pigments accumulated in the ethanol phase, and the hydrolysis product, phthalic acid, remained in the hydrolysate...
December 9, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29222018/physicochemical-properties-and-biological-activities-of-polysaccharides-from-lycium-barbarum-prepared-by-fractional-precipitation
#6
Guiping Gong, Tiantian Dang, Yangni Deng, Jianli Han, Sun Jing, Ying Zhang, Linjuan Huang, Zhongfu Wang
Traditional separation and purification process of Lycium barbarum polysaccharide (LBP) includes water extraction, alcohol precipitation, deproteinization and ion-exchange column chromatography, which is complicated and time-consuming. In our study, non-dialyzable LBP-I and dialyzable LBP-O were obtained from LBP by water extraction, alcohol precipitation and deproteinization. LBP-I was separated by fractional precipitation and three fractions (LBP-I-1, LBP-I-2 and LBP-I-3) were obtained. The three fractions were further purified by gel permeation chromatography to LBGP-I-1, LBGP-I-2 and LBGP-I-3 with yields of 0...
December 5, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29222013/purification-structural-features-and-immunostimulatory-activity-of-novel-polysaccharides-from-caulerpa-lentillifera
#7
Yujiao Sun, Guiping Gong, Yiming Guo, Zhongfu Wang, Shuang Song, Beiwei Zhu, Lili Zhao, Jinju Jiang
In this study, four purified fractions (CLGP1, CLGP2, CLGP3 and CLGP4) were prepared from green seaweed Caulerpa lentillifera. They were identified to be a novel kind of xylogalactomanans, differed in molecular weight, monosaccharide composition, and the content of uronic acids and sulfate groups, leading to various ζ-potential, ultrastructure and immunostimulatory activity. Especially, CLGP4 was quite different from the others, as it was found to be a homogeneous heteropolysaccharide composed of Xyl, Man and Gal in a percentage ratio of 1...
December 5, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29221728/emulsified-isoflurane-induces-release-of-cytochrome-c-in-human-neuroblastoma-shsy-5y-cells-via-jnk-c-jun-n-terminal-kinases-signaling-pathway
#8
Zeyong Yang, Jingjing Lv, Xianfu Lu, Xingxing Li, Xiaohu An, Jianwei Wang, Hao Weng, Yuanhai Li
A large number of studies have demonstrated that inhalation anesthetic isoflurane induced neural cell death by apoptosis in various cell and animal models. Emulsified isoflurane (EIso) is a new type of intravenous preparation of isoflurane that attracts increasing research attention as a promising clinical agent due to its both advantages as an intravenous and inhalation anesthetics medication. However, its safety and underlying molecular mechanism of neurotoxicity largely remain unknown. Therefore, it is meaningful to investigate the safety of EIso and to further elucidate its mechanism of anesthetic neurotoxicity...
December 5, 2017: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/29221542/ability-to-pay-for-future-national-health-financing-scheme-among-malaysian-households
#9
Azimatun Noor Aizuddin, Syed Mohamed Aljunid
BACKGROUND: Malaysia is no exception to the challenging health care financing phenomenon of globalization. OBJECTIVES: The objective of the present study was to assess the ability to pay among Malaysian households as preparation for a future national health financing scheme. METHODS: This was a cross-sectional study involving representative samples of 774 households in Peninsular Malaysia. FINDINGS: A majority of households were found to have the ability to pay for their health care...
May 2017: Annals of Global Health
https://www.readbyqxmd.com/read/29220524/brain-responses-to-cigarette-related-and-emotional-images-in-smokers-during-smoking-cessation-no-effect-of-varenicline-or-bupropion-on-the-late-positive-potential
#10
Francesco Versace, Elise M Stevens, Jason D Robinson, Yong Cui, Menton M Deweese, Jeffrey M Engelmann, Charles E Green, Maher Karam-Hage, Cho Y Lam, Jennifer A Minnix, David W Wetter, Paul M Cinciripini
Introduction: Varenicline and bupropion are two effective smoking cessation pharmacotherapies. Researchers have hypothesized that they might be effective, in part, because they reduce cue reactivity and cue-induced cravings. Here, we used event-related potentials (ERPs) to directly measure brain responses to cigarette-related and other motivationally relevant images during a pharmacologically aided quit attempt. Methods: Smokers involved in a 12-week placebo-controlled double-blind clinical trial of smoking cessation medications (varenicline, bupropion, placebo) took part in the study...
December 6, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29220411/hexahydrocurcumin-protects-against-cerebral-ischemia-reperfusion-injury-attenuates-inflammation-and-improves-antioxidant-defenses-in-a-rat-stroke-model
#11
Piyawadee Wicha, Jiraporn Tocharus, Adchara Janyou, Jinatta Jittiwat, Chatchawan Changtam, Apichart Suksamrarn, Chainarong Tocharus
The purpose of the present experiment was to investigate whether hexahydrocurcumin (HHC) attenuates brain damage and improves functional outcome via the activation of antioxidative activities, anti-inflammation, and anti-apoptosis following cerebral ischemia/reperfusion (I/R). In this study, rats with cerebral I/R injury were induced by a transient middle cerebral artery occlusion (MCAO) for 2 h, followed by reperfusion. The male Wistar rats were randomly divided into five groups, including the sham-operated, vehicle-treated, 10 mg/kg HHC-treated, 20 mg/kg HHC-treated, and 40 mg/kg HHC-treated I/R groups...
2017: PloS One
https://www.readbyqxmd.com/read/29220361/pre-stimulus-pupil-dilation-and-the-preparatory-control-of-attention
#12
Jessica L Irons, Minjeong Jeon, Andrew B Leber
Task preparation involves multiple component processes, including a general evaluative process that signals the need for adjustments in control, and the engagement of task-specific control settings. Here we examined the dynamics of these different mechanisms in preparing the attentional control system for visual search. We explored preparatory activity using pupil dilation, a well-established measure of task demands and effortful processing. In an initial exploratory experiment, participants were cued at the start of each trial to search for either a salient color singleton target (an easy search task) or a low-salience shape singleton target (a difficult search task)...
2017: PloS One
https://www.readbyqxmd.com/read/29219883/zika-virus-and-the-rio-olympic-games
#13
Bruce Hamilton, Dan Exeter, Sarah Beable, Lynne Coleman, Chris Milne
OBJECTIVE: To evaluate the impact of Zika virus on preparation and management of the New Zealand (NZ) Olympic team. DESIGN: Descriptive manuscript. SETTING: New Zealand Olympic Health team preparation and management during the Rio de Janeiro Olympic Games, 2016. PATIENTS (OR PARTICIPANTS): New Zealand Olympic Team members. INTERVENTIONS (OR ASSESSMENT OF RISK FACTORS): This manuscript describes the approaches used by the NZ Olympic Health team to the minimization of risk from Zika virus...
December 1, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29219880/the-health-information-technology-competencies-tool-does-it-translate-for-nursing-informatics-in-the-united-states
#14
Carolyn Sipes, Kathleen Hunter, Dee McGonigle, Karen West, Taryn Hill, Toni Hebda
Information technology use in healthcare delivery mandates a prepared workforce. The initial Health Information Technology Competencies tool resulted from a 2-year transatlantic effort by experts from the US and European Union to identify approaches to develop skills and knowledge needed by healthcare workers. It was determined that competencies must be identified before strategies are established, resulting in a searchable database of more than 1000 competencies representing five domains, five skill levels, and more than 250 roles...
December 2017: Computers, Informatics, Nursing: CIN
https://www.readbyqxmd.com/read/29219839/efficient-exfoliation-of-layered-materials-by-waste-liquor
#15
Jiheng Ding, Hongran Zhao, Yan Zheng, Qiaolei Wang, Hao Chen, Huimin Dou, Haibin Yu
Based on the unique material properties, two-dimensional (2D) nanomaterials such as graphene, molybdenum disulfide (MoS2), and boron nitride (BN) have been attracting increasing research interest. The potential of 2D materials in the form of nanoplatelets used as new materials will be important to both nanomaterials and advanced materials. Usually water is considered as the ideal dispersed medium, while the essential hydrophobicity of 2D nanoplatelets and limitation of mass production became the quite serious obstacles for the usage in various fields...
December 8, 2017: Nanotechnology
https://www.readbyqxmd.com/read/29218856/preparation-of-fluoride-loaded-microcapsules-for-anticariogenic-bacterial-growth-using-a-coaxial-ultrasonic-atomizer
#16
Hae-Won Choi, Seung-Hoon Um, Sang-Hoon Rhee
A new method to deliver fluoride using biodegradable poly(lactic-co-glycolic acid) microcapsules to suppress cariogenic bacterial growth during orthodontic treatment was investigated. A coaxial ultrasonic atomizer was used to encapsulate KF solution into microcapsules. The orthodontic adhesive resin disk containing fluoride loaded microcapsules (DFLM) was prepared by LED light curing. The microstructure of microcapsules, successful loading of KF, fracture strength, and shear bonding strength were assessed by FE-SEM, confocal laser scanning microscope, and general purpose testing machine, respectively...
January 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29218721/functional-characterization-of-a-second-pedal-peptide-orcokinin-type-neuropeptide-signaling-system-in-the-starfish-asterias-rubens
#17
Ming Lin, Michaela Egertová, Cleidiane G Zampronio, Alexandra M Jones, Maurice R Elphick
Molluscan pedal peptides (PP) and arthropod orcokinins (OK) are prototypes of a family of neuropeptides that have been identified in several phyla. Recently, starfish myorelaxant peptide (SMP) was identified as a PP/OK-type neuropeptide in the starfish Patiria pectinifera (phylum Echinodermata). Furthermore, analysis of transcriptome sequence data from the starfish Asterias rubens revealed two PP/OK-type precursors: an SMP-type precursor (A. rubens pedal peptide-like neuropeptide precursor 1; ArPPLNP1) and a second precursor (ArPPLNP2)...
December 8, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/29218708/three-dimensional-reconstruction-of-the-cranial-and-anterior-spinal-nerves-in-early-tadpoles-of-xenopus-laevis-pipidae-anura
#18
Benjamin Naumann, Lennart Olsson
Xenopus laevis is one of the most widely used model organism in neurobiology. It is therefore surprising, that no detailed and complete description of the cranial nerves exists for this species. Using classical histological sectioning in combination with fluorescent whole mount antibody staining and micro-computed tomography we prepared a detailed innervation map and a freely-rotatable 3D model of the cranial nerves and anterior-most spinal nerves of early X. laevis tadpoles. Our results confirm earlier descriptions of the pre-otic cranial nerves and present the first detailed description of the post-otic cranial nerves...
December 8, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/29218633/characterization-of-the-one-electron-oxidized-cu-ii-salen-complexes-with-a-side-chain-aromatic-ring-the-effect-of-the-indole-ring-on-the-cu-ii-phenoxyl-radical-species
#19
Hiromi Oshita, Takayoshi Yoshimura, Seiji Mori, Fumito Tani, Yuichi Shimazaki, Osamu Yamauchi
To gain insights into the role of the proximal indole ring in the redox-active metal center as seen in galactose oxidase, we prepared the Cu(II)-salen-type complexes having a pendent indol-3-ylmethyl (1), methyl (2) or benzyl (3) group substituted on the ethylenediamine moiety and investigated the structures and redox properties by various physicochemical methods and theoretical calculations. Neutral complexes 1, 2, and 3 showed no significant difference in the UV-Vis-NIR and EPR spectra. One-electron oxidation of 1, 2, and 3 by addition of 1 equiv...
December 7, 2017: Journal of Biological Inorganic Chemistry: JBIC
https://www.readbyqxmd.com/read/29218581/fabrication-of-tip-dissolving-microneedles-for-transdermal-drug-delivery-of-meloxicam
#20
Jianmin Chen, Weiyue Huang, Ziyao Huang, Shiqi Liu, Yaling Ye, Qinglian Li, Meiping Huang
Dissolving microneedles (MNs) offered a simple, minimally invasive method for meloxicam (MX) delivery to the skin. However, the fabrication of dissolving MNs still faced some challenges, such as significant time consumption, loss of drug activity, and difficulty in regulating MN drug loading. To address these issues, we developed the tip-dissolving (TD) MNs. Several kinds of drugs were encapsulated successfully, and the quantity of MX ranged from 37.23 ± 8.40 to 332.53 ± 13.37 μg was precisely controlled...
December 7, 2017: AAPS PharmSciTech
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