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Migraine and treatment

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https://www.readbyqxmd.com/read/28932372/acupuncture-and-botulinum-toxin-a-injection-in-the-treatment-of-chronic-migraine-a-randomized-controlled-study
#1
Bahram Naderinabi, Alia Saberi, Masood Hashemi, Mohammad Haghighi, Gelareh Biazar, Farid Abolhasan Gharehdaghi, Abbas Sedighinejad, Tahereh Chavoshi
BACKGROUND: Migraine is a common type of headache. Sometimes adequate pain relief is not achieved by conventional treatments. Acupuncture and botulinum toxin-A injection are known as non-pharmacological interventions for this purpose. The aim of this research was to compare the effect of acupuncture with botulinum toxin-A injection and pharmacological treatment in controlling chronic migraine. METHODS: This clinical trial was conducted on patients with chronic migraine in the North of Iran during 2014-2015...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/28931106/a-case-of-prethoracic-pain-radiating-upward-and-initiating-nervus-intermedius-neuralgia-and-migraine-headache-could-epicrania-fugax-pain-start-in-the-upper-body
#2
Yu Wang, Pei-Lin Kan, Yuan-Feng Tao, Xiao-Yan Li, Xiao-Juan Yang, Gui-Ling Liang
Epicrania fugax (EF) was recently classified as a primary headache in the Appendix of the International Classification of Headache Disorders, third edition (ICHD-III). It is characterized by a paroxysmal pain rapidly radiating forward or backward along a linear or zigzag trajectory on the surface of the head. This article reports a 76-year-old woman who newly developed a paroxysmal EF-type pain distributed not only in the territories of the trigeminal and occipital nerves, but also in the territories of the cervical and thoracic nerves...
September 20, 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/28926506/family-perspectives-on-visiting-the-pediatric-emergency-department-for-migraine-a-qualitative-study
#3
Serena Laura Orr, Liam OʼSullivan, Roger Zemek, Natalie M Ward, Hugh J McMillan
OBJECTIVE: The aim of this study was to explore the perspectives of families regarding their expectations and experience of visiting the emergency department (ED) for migraine. METHODS: This was a qualitative study involving the families of 25 patients aged 10 to 18 years receiving ED care for acute migraine. Following their visit, independent semistructured telephone interviews were conducted with both the patient and parent or guardian. Questions were designed to explore factors pertaining to the family's perspective regarding their visit to the ED and expectations for the ED visit...
September 18, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28925885/spreading-depolarization-waves-in-neurological-diseases-a-short-review-about-its-pathophysiology-and-clinical-relevance
#4
Yağmur Çetin Taş, İhsan Solaroğlu, Yasemin Gürsoy-Özdemir
Lesion growth following acutely injured brain tissue after stroke, subarachnoid hemorrhage and traumatic brain injury is an important issue and a new target area for promising therapeutic interventions. Spreading depolarization or peri-lesion depolarization waves were demonstrated as one of the significant contributors of continued lesion growth. In this short review, we discuss the pathophysiology for SD forming events and try to list findings detected in neurological disorders like migraine, stroke, subarachnoid hemorrhage and traumatic brain injury in both human as well as experimental studies...
September 15, 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/28925498/electronic-diary-for-recording-headaches-triggers-and-medication-use-development-and-evaluation
#5
Siavash Bandarian-Balooch, Paul R Martin, Brenton McNally, Arissa Brunelli, Sharon Mackenzie
OBJECTIVE: To evaluate an e-diary developed for measuring headaches, triggers, and medication consumption, in terms of reliability and validity, and variables such as ease of use and participant compliance. BACKGROUND: For many decades, behavioral treatment of headaches has been evaluated via participants completing paper diaries recording their headaches and associated phenomena. There is some limited evidence supporting the reliability and validity of paper diaries, and criticisms have been offered such as the large amount of effort involved for both participants and researchers...
September 19, 2017: Headache
https://www.readbyqxmd.com/read/28920448/assessing-the-impact-of-headaches-and-the-outcomes-of-treatment-a-systematic-review-of-patient-reported-outcome-measures-proms
#6
Kirstie L Haywood, Tom S Mars, Rachel Potter, Shilpa Patel, Manjit Matharu, Martin Underwood
Aims To critically appraise, compare and synthesise the quality and acceptability of multi-item patient reported outcome measures for adults with chronic or episodic headache. Methods Systematic literature searches of major databases (1980-2016) to identify published evidence of PROM measurement and practical properties. Data on study quality (COSMIN), measurement and practical properties per measure were extracted and assessed against accepted standards to inform an evidence synthesis. Results From 10,903 reviewed abstracts, 103 articles were assessed in full; 46 provided evidence for 23 PROMs: Eleven specific to the health-related impact of migraine (n = 5) or headache (n = 6); six assessed migraine-specific treatment response/satisfaction; six were generic measures...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28918732/acupuncture-for-analgesia-in-the-emergency-department-a-multicentre-randomised-equivalence-and-non-inferiority-trial
#7
Marc M Cohen, De Villiers Smit, Nick Andrianopoulos, Michael Ben-Meir, David McD Taylor, Shefton J Parker, Chalie C Xue, Peter A Cameron
OBJECTIVES: This study aimed to assess analgesia provided by acupuncture, alone or in combination with pharmacotherapy, to patients presenting to emergency departments with acute low back pain, migraine or ankle sprain. DESIGN: A pragmatic, multicentre, randomised, assessor-blinded, equivalence and non-inferiority trial of analgesia, comparing acupuncture alone, acupuncture plus pharmacotherapy, and pharmacotherapy alone for alleviating pain in the emergency department...
June 19, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28915242/a-retrospective-cost-analysis-of-additional-homeopathic-treatment-in-germany-long-term-economic-outcomes
#8
Julia K Ostermann, Claudia M Witt, Thomas Reinhold
OBJECTIVES: This study aimed to provide a long-term cost comparison of patients using additional homeopathic treatment (homeopathy group) with patients using usual care (control group) over an observation period of 33 months. METHODS: Health claims data from a large statutory health insurance company were analysed from both the societal perspective (primary outcome) and from the statutory health insurance perspective (secondary outcome). To compare costs between patient groups, homeopathy and control patients were matched in a 1:1 ratio using propensity scores...
2017: PloS One
https://www.readbyqxmd.com/read/28905127/adhd-is-associated-with-migraine-a-systematic-review-and-meta-analysis
#9
REVIEW
Haitham Salem, David Vivas, Fei Cao, Iram F Kazimi, Antonio L Teixeira, Cristian P Zeni
An association between primary headaches and attention-deficit/hyperactivity disorder (ADHD) has long been suggested. Moreover, headache is regarded as a common side effect of stimulants, the most effective treatment for ADHD. So far, no systematic review has evaluated the potential association between ADHD and headache. We performed a systematic review of the literature and a meta-analysis of all reported studies on ADHD and primary headaches. Our analysis showed a positive association between ADHD and migraine (OR 1...
September 13, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28903615/a-study-of-oxidative-stress-in-migraine-with-special-reference-to-prophylactic-therapy
#10
Gyanesh M Tripathi, Jayantee Kalita, Usha K Misra
OBJECTIVE: This study has been undertaken to evaluate the role of oxidative stress markers in migraine and effect of treatment on these markers. SUBJECT AND METHODS: 150 patients having more than 4 attacks of migraine headache per month were included.Headache severity was determined by Migraine Index (MI) and Frequency of headache was noted. 120 patients received rTMS therapy and 30 patients received AMT daily Recovery was defined by 50% improvement in frequency or severity or reduction in MI...
September 14, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28901847/micrornas-to-monitor-pain-migraine-and-drug-treatment
#11
Luca Gallelli, Erika Cione, Maria Cristina Caroleo, Marco Carotenuto, Pasqualina Lagana, Antonio Siniscalchi, Vincenzo Guidetti
Migraine is a prevalent neurovascular disorders with a complex pathophysiology and therapeutic options characterized by important side effects or problems related to drug abuse. No specific biomarkers are recognized to be univocal for this subclinical condition, yet. In this concern microRNAs have been suggested as potentially useful screening/diagnostic tool, and research is underway to recognize the most effective candidate(s). microRNAs, able to regulate immune and neuronal processes are herein reported for both, mice models with multiple induced pain conditions and human subjects...
September 12, 2017: MicroRNA
https://www.readbyqxmd.com/read/28901169/predictors-of-response-to-occipital-nerve-stimulation-in-refractory-chronic-headache
#12
Sarah Miller, Laurence Watkins, Manjit Matharu
Background Occipital nerve stimulation is a promising treatment for refractory chronic headache disorders, but is invasive and costly. Identifying predictors of response would be useful in selecting patients. We present the results of an open-label prospective cohort study of 100 patients (35 chronic migraine, 33 chronic cluster headache, 20 short-lasting unilateral neuralgiform headache attacks and 12 hemicrania continua) undergoing occipital nerve stimulation, using a multivariate binary regression analysis to identify predictors of response...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28900742/relationship-between-air-mass-type-and-emergency-department-visits-for-migraine-headache-across-the-triangle-region-of-north-carolina
#13
Christopher Elcik, Christopher M Fuhrmann, Andrew E Mercer, Robert E Davis
An estimated 240 million people worldwide suffer from migraines. Because migraines are often debilitating, understanding the mechanisms that trigger them is crucial for effective prevention and treatment. Synoptic air mass types and emergency department (ED) visits for migraine headaches were examined over a 7-year period within a major metropolitan area of North Carolina to identify potential relationships between large-scale meteorological conditions and the incidence of migraine headaches. Barometric pressure changes associated with transitional air masses, or changing weather patterns, were also analyzed for potential relationships...
September 13, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/28899786/artemin-transiently-increases-inos-expression-in-primary-cultured-trigeminal-ganglion-neurons
#14
Haiqiong Shang, Yan Wang, Xiuhua Chao, Gaoying Sun, Xiaohui Bai, Lei Xu, Yuechen Han, Jianfeng Li, Haibo Wang, Zhaomin Fan
Artemin, a member of the glial cell line-derived neurotrophic factor family, is an important cytokine and a critical participant in trigeminal pain disorders such as tongue pain and migraine. However, the mechanisms underlying artemin's activity are largely unknown. In the present study, we used primary cultured trigeminal ganglion neurons (TGNs) to determine the effect of artemin on the expression of the inducible form of nitric oxide synthase (iNOS), which is released in response to painful and inflammatory stimuli...
September 9, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28899205/non-invasive-vagus-nerve-stimulation-for-the-management-of-refractory-primary-chronic-headaches-a-real-world-experience
#15
Michele Trimboli, Adnan Al-Kaisy, Anna P Andreou, Madeleine Murphy, Giorgio Lambru
Background Non-invasive vagus nerve stimulation has initial evidence of efficacy in migraine and cluster headache. However, little is known about its role in the management of refractory chronic headaches. Methods We evaluated the preventive and abortive effects of non-invasive vagus nerve stimulation in 41 consecutive patients with refractory primary chronic headaches in an open-label prospective clinical audit. Headache diaries were used to collect clinical information. Those who obtained at least 30% reduction in headache days/episodes after three months of treatment were considered responders and were offered treatment continuation...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28891872/vertigo-in-vestibular-schwannoma-patients-due-to-other-pathologies
#16
Ronald Sahyouni, Omid Moshtaghi, Yarah M Haidar, Hossein Mahboubi, Afsheen Moshtaghi, Harrison W Lin, Hamid R Djalilian
OBJECTIVE: To report findings from a cohort of vestibular schwannoma (VS) patients presenting with vertigo from a secondary comorbid vestibular disorder; and to discuss management strategies for this subset of patients presenting with both episodic vertigo and VS. PATIENTS: All VS patients who presented with vertigo as the primary symptom from 2012 to 2015 and endorsing no other major complaints were examined. INTERVENTION: Treatment with migraine lifestyle and prophylactic therapy, or Epley maneuver...
September 7, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28890798/american-football-and-other-sports-injuries-may-cause-migraine-persistent-pain-decades-later-and-can-be-treated-successfully-with-electrical-twitch-obtaining-intramuscular-stimulation-etoims
#17
J Chu, S McNally, F Bruyninckx, D Neuhauser
INTRODUCTION: Autonomous twitch elicitation at myofascial trigger points from spondylotic radiculopathies-induced denervation supersensitivity can provide favourable pain relief using electrical twitch-obtaining intramuscular stimulation (ETOIMS). AIM: To provide objective evidence that ETOIMS is safe and efficacious in migraine and persistent pain management due to decades-old injuries to head and spine from paediatric American football. METHODS AND MATERIALS: An 83-year-old mildly hypertensive patient with 25-year history of refractory migraine and persistent pain self-selected to regularly receive fee-for-service ETOIMS 2/week over 20 months...
April 2017: BMJ Innovations
https://www.readbyqxmd.com/read/28886861/primary-headache-disorders-part-2-tension-type-headache-and-medication-overuse-headache
#18
Gary W Jay, Robert L Barkin
In Part 2 of Primary Headache disorders, we discuss the fourth Primary Headache Disorder, Tension-Type Headache (TTHA). We are again using the ICHD-III (Beta) definitions of such headaches, taking into consideration episodic and chronic TTHA, as well as the presence or absence of pericranial muscle tenderness. We discuss the pathophysiology and pharmacotherapeutic treatment of TTHA, and the aspects of the Myofascial Pain Syndrome that enhance and help the development of TTHA. We then discuss Medication Overuse Headache (MOH), itself a Secondary headache disorder, but one that is extremely important as it assists with the chronification of both migraine and TTHA...
September 5, 2017: Disease-a-month: DM
https://www.readbyqxmd.com/read/28886860/primary-headache-disorders-part-i-migraine-and-the-trigeminal-autonomic-cephalalgias
#19
Gary W Jay, Robert L Barkin
In Primary Headache Disorders, Part 1, we discuss three of the primary headache disorders using the headache definitions from ICHD-III (Beta): Migraine, with and without aura; its pathophysiology and treatment are discussed. We then discuss the Trigeminal Autonomic Cephalalgias (TACs), including Cluster Headache and Hemicrania Continua, two more primary headache disorders, as well as the other TAC Headaches. We discuss pathophysiology as well as diagnosis, treatment, and pharmacotherapeutic management of these headache diatheses...
September 5, 2017: Disease-a-month: DM
https://www.readbyqxmd.com/read/28885085/targeting-the-central-projection-of-the-dural-trigeminovascular-system-for-migraine-prophylaxis
#20
Simon Akerman, Marcela Romero-Reyes
Migraine abortives likely target both peripheral-dural and central trigeminovascular mechanisms in mediating their therapeutic effects. However, in preclinical assays, many migraine preventives have little success at inhibiting similar trigeminovascular-mediated peripheral changes within the dural microenvironment. In addition, their effects on central trigeminovascular neuronal responses are largely unknown. Using a validated preclinical model of acute dural-intracranial (migraine-like) head pain, using Sprague Dawley rats, we tested whether migraine preventives suppress ongoing firing of central trigeminocervical neurons, and evoked responses to cranial neurovascular activation...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
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