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https://www.readbyqxmd.com/read/29437739/a-foreign-older-diabetic-woman-with-an-acute-myocardial-infarction-when-cognitive-biases-in-clinical-decision-making-become-especially-important
#1
Mathias Schlögl, Daniel Hofmänner, Robert Manka, Dagmar I Keller
We present a case of an 80-year-old Turkish female patient with diabetes who suffered an acute myocardial infarction (AMI) and underwent percutaneous coronary balloon angioplasty (PTCA)/stenting. Due to new ischaemic episodes, a second PTCA/stenting had to be preformed 6 days later, which revealed a partial restent thrombosis. This case report raises several important issues. First, language problems are an important barrier for safety and quality in healthcare. Second, gender, ethnicity and age differences in patients with AMI need to be considered in order to eliminate inequities in clinical practice...
February 5, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29398633/incidence-predictors-and-long-term-clinical-outcome-of-angiographic-definite-stent-thrombosis-in-real-world-scenario-a-prospective-cohort-study
#2
Bhupinder Singh, Basvappa Ramesh, Ravindran Rajendran, Yadvinder Singh, Vivek Singla, Vikram B Kolhari, Abhishek Goyal, Bishav Mohan, Naved Aslam, Shibba Takkar Chhabra, Gurpreet Singh Wander, Manjunath Cholenhally Nanjappa
BACKGROUND: The occurrence of stent thrombosis (ST) in real world scenario is far different from that mentioned in the literature. Our study identifies the various parameters of ST. METHODS: This is a prospective observational-cohort study where-in consecutive patients who received successful percutaneous transluminal angioplasty (PTCA) over the study period of 1-year was included and were followed for 1-year from the primary procedure. RESULTS: The overall incidence of definite ST was 1...
January 4, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29380743/radiation-dose-from-percutaneous-transluminal-coronary-angioplasty-procedure-performed-using-flat-detector-for-different-clinical-angiographic-projections
#3
Anna Varghese, Roshan Samuel Livingstone, Lijo Varghese, Subhrangshu Dey, John Jose, Viji Samuel Thomson, Oommen K George, Paul V George
Radiation dose from complex cardiac procedures are of concern due to lengthy fluoroscopic screening time and vessel complexities. This study intends to assess radiation dose based on angiographic projection and vessel complexities for clinical protocols used in performing percutaneous transluminal coronary angioplasty (PTCA) procedure. Dose area product (DAP), reference air kerma (Ka,r) and real time monitoring of tube potentials and tube current for each angiographic projection and dose setting were evaluated for 66 patients who underwent PTCA using flat detector system...
January 30, 2018: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/29324283/a-novel-electrochemiluminescent-biosensor-based-on-resonance-energy-transfer-between-poly-9-9-di-n-octylfluorenyl-2-7-diyl-and-3-4-9-10-perylenetetracar-boxylic-acid-for-insulin-detection
#4
Han Zhang, Fumei Zuo, Xingrong Tan, Shenghao Xu, Ruo Yuan, Shihong Chen
An electrochemiluminescencent (ECL) biosensor was designed for the determination of insulin using a novel ECL resonance energy transfer (ECL-RET) strategy. In this strategy, carboxyl poly(9,9-dioctyfluorenyl-2,7-diyl) dots (PFO dots) were worked as ECL donor and 3,4,9,10-perylenetetracar-boxylic acid (PTCA) exploited as ECL acceptor, and hydrogen peroxide (H2O2) employed as the coreactant. The ECL donor and ECL acceptor were separately labeled with primary antibody (Ab1) and secondary antibody (Ab2), forming a sensing interface to the analyte target, insulin...
December 27, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29319132/evaluation-of-changes-in-perfusion-defect-and-left-ventricular-systolic-function-using-tc-99m-tetrofosmin-single-photon-emission-computed-tomography-over-3-month-period-in-patients-of-acute-myocardial-infarction-undergoing-primary-angioplasty
#5
Anil Kumar Avs, P G Kumar, Ajay Swami, Yiteedra Dinker
BACKGROUND: After a primary transluminal coronary angioplasty (PTCA) following AMI (acute myocardial infarction), the perfusion defect and LV (left ventricular) function recover/change over a period of time. The analysis immediately after the procedure may not be true depiction of the exact success of the procedure. There is varying and scanty information available on the natural course of changes in these parameters after a successful PTCA. We hypothesized that majority of change occurs at 3-4 month period...
January 10, 2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29283130/color-doppler-imaging-of-the-retrobulbar-circulation-and-plasmatic-biomarkers-of-vascular-risk-in-age-related-macular-degeneration-a-pilot-study
#6
Fermin Rodrigo, José María Ruiz-Moreno, Juan Bernabé García, María Eugenia Torregrosa, José Vicente Segura, David P Piñero
PURPOSE: To evaluate preliminarily and compare the level of plasmatic biomarkers of vascular risk in patients with and without exudative age-related macular degeneration (ARMD) and to relate it to vascular resistance alterations in the ophthalmic artery (OA), central retinal artery (CRA), posterior temporal ciliary artery (PTCA), and posterior nasal ciliary artery (PNCA). METHODS: Color Doppler imaging of the OA, CRA, PTCA, and PNCA was performed in 30 eyes of 30 cataract patients (control group) as well as in 30 eyes of 30 patients with naive exudative ARMD (study group), measuring the peak systolic velocity, end-diastolic velocity (EDV), and Pourcelot resistive index (RI)...
January 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29275222/perylenetetracarboxylic-acid-and-carbon-quantum-dots-assembled-synergistic-electrochemiluminescence-nanomaterial-for-ultra-sensitive-carcinoembryonic-antigen-detection
#7
Lan-Lan Xu, Wei Zhang, Lei Shang, Rong-Na Ma, Li-Ping Jia, Wen-Li Jia, Huai-Sheng Wang, Li Niu
It is important to design a nice electrochemiluminescence (ECL) biological nanomaterial for fabricating sensitive ECL immunosensor to detect tumor markers. Most reported ECL nanomaterial was decorated by a number of mono-luminophore. Here, we report a novel ECL nanomaterial assembled by dual luminophores perylenetetracarboxylic acid (PTCA) and carbon quantum dots (CQDs). In the ECL nanomaterial, graphene was chosen as nanocarrier. Significant ECL intensity increases are seen in the ECL nanomaterial, which was interpreted with the proposed synergistic promotion ECL meachanism of PTCA and CQDs...
October 17, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29174243/evaluation-and-efficacy-of-long-length-pronova-xr-bioabsorbable-polymer-stent-in-the-treatment-of-long-coronary-lesions
#8
M S Hiremath
AIM: The study aims an observational registry of the long and extra-long length (>33mm) Pronova XR stents in patients with long coronary lesions (>30mm) in a prospective real world study. METHODS AND RESULTS: Current study was conducted at Ruby Hall Clinic Pune, between July 2012 and July 2013 including 30 patients who underwent PTCA using long and extra-long Pronova XR stents. Among the stents used, one stent - 33mm, 2 stents - 38mm, 5 stents - 43mm and 25 stents were of 48mm in length...
November 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/29171182/acid-hydrolysis-reveals-a-low-but-constant-level-of-pheomelanin-in-human-black-to-brown-hair
#9
Shosuke Ito, Shiho Miyake, Shoji Maruyama, Itaru Suzuki, Stéphane Commo, Yukiko Nakanishi, Kazumasa Wakamatsu
We previously reported a constant ratio of the benzothiazole-pheomelanin marker thiazole-2,4,5-tricarboxylic acid (TTCA) to the eumelanin marker pyrrole-2,3,5-tricaboxylic acid (PTCA) in eumelanic, black human hair. A constant level (20-25%) of benzothiazole-type pheomelanin was recently demonstrated in human skin with varying concentrations of melanin. Therefore, in this study, we aimed to investigate the origin of pheomelanin markers in black to brown human hair by developing a method to remove protein components from hair by heating with 6 M HCl at 110°C for 16 h...
November 24, 2017: Pigment Cell & Melanoma Research
https://www.readbyqxmd.com/read/29055192/electrochemical-immunosensor-with-nanocellulose-au-composite-assisted-multiple-signal-amplification-for-detection-of-avian-leukosis-virus-subgroup-j
#10
Chao Liu, Jing Dong, Geoffrey I N Waterhouse, Ziqiang Cheng, Shiyun Ai
A sensitive sandwich-type electrochemical immunosensor was developed for the detection of avian leukosis virus subgroup J (ALV-J), which benefitted from multiple signal amplification involving graphene-perylene-3,4,9,10-tetracarboxylic acid nanocomposites (GR-PTCA), nanocellulose-Au NP composites (NC-Au) and the alkaline phosphatase (ALP) catalytic reaction. GR-PTCA nanocomposites on glassy carbon electrodes served as the immunosensor platform. Due to their excellent electrical conductivity and abundant polycarboxylic sites, the GR-PTCA nanocomposites allowed fast electron transfer and good immobilization of primary antibodies, thereby affording a strong immunosensor signal in the presence of ALV-J...
October 3, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28965054/hemin-as-electrochemically-regenerable-co-reaction-accelerator-for-construction-of-an-ultrasensitive-ptca-based-electrochemiluminescent-aptasensor
#11
Wei-Jia Zeng, Ni Liao, Yan-Mei Lei, Jing Zhao, Ya-Qin Chai, Ruo Yuan, Ying Zhuo
In this work, hemin was firstly used as electrochemically regenerable co-reaction accelerator for signal amplification to develop an ultrasensitive aptasensor for Aflatoxin M1 (AFM1) detection. Initially, the perylenetetracarboxylic acid (PTCA) was directly employed as luminophore to construct the ECL sensing nano-platform by combining Au nanoparticles (Au NPs) for immobilizing thiol-terminated hairpin probe (H1). Then with the help of hairpin H2, H3, the AFM1-catalyzed hairpin assembly (CHA) was executed to produce the H1-H3 duplex, which could further initiate the hybridization chain reaction (HCR) to generate dendritic DNA polymers consisting of G-rich sequence for capturing large quantities of hemin on the electrode surface...
September 22, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28940782/ptca-1h-pyrrole-2-3-5-tricarboxylic-acid-as-a-marker-for-oxidative-hair-treatment
#12
Silvana Petzel-Witt, Sylvia I Meier, Manfred Schubert-Zsilavecz, Stefan W Toennes
Hair analysis for the assessment of alcohol or drug abstinence became a routine procedure in forensic toxicology. Hair coloration leading to loss of incorporated xenobiotics and to false negative results turned out to be a major problem. Currently only colored extracts provide hints of manipulations but not bleaching. A liquid chromatographic-mass spectrometric (LC-MSMS) method was developed and validated to determine 1H-pyrrole-2,3,5-tricarboxylic acid (PTCA), a major oxidation product of melanin. PTCA was determined in natural hair samples (n=21) after treatment with 3% hydrogen peroxide (H2 O2 ) for 30 or 40 min with concentrations up to 12% for 40 min...
September 20, 2017: Drug Testing and Analysis
https://www.readbyqxmd.com/read/28873228/photodegradation-of-eumelanin-and-pheomelanin-and-its-pathophysiological-implications
#13
REVIEW
Shosuke Ito, Kazumasa Wakamatsu, Tadeusz Sarna
Eumelanin is photoprotective for pigmented tissues while pheomelanin is phototoxic. In this review, we summarize current understanding of how eumelanin and pheomelanin structures are modified by ultraviolet A (UVA) and also by visible light and how reactive oxygen species participate in those processes. Alkaline hydrogen peroxide oxidation was employed to characterize eumelanin and benzothiazole-type pheomelanin, giving pyrrole-2,3,5-tricarboxylic acid (PTCA) and thiazole-2,4,5-tricarboxylic acid (TTCA), respectively...
September 5, 2017: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/28864195/flow-injection-amperometric-sandwich-type-aptasensor-for-the-determination-of-human-leukemic-lymphoblast-cancer-cells-using-mwcnts-pdnano-ptca-aptamer-as-labeled-aptamer-for-the-signal-amplification
#14
Mahmoud Amouzadeh Tabrizi, Mojtaba Shamsipur, Reza Saber, Saeed Sarkar
In this research, we demonstrated a flow injection amperometric sandwich-type aptasensor for the determination of human leukemic lymphoblasts (CCRF-CEM) based on poly(3,4-ethylenedioxythiophene) decorated with gold nanoparticles (PEDOT-Aunano) as a nano platform to immobilize thiolated sgc8c aptamer and multiwall carbon nanotubes decorated with palladium nanoparticles/3,4,9,10-perylene tetracarboxylic acid (MWCNTs-Pdnano/PTCA) to fabricate catalytic labeled aptamer. In the proposed sensing strategy, the CCRF-CEM cancer cells were sandwiched between immobilized sgc8c aptamer on PEDOT-Aunano modified surface electrode and catalytic labeled sgc8c aptamer (MWCNTs-Pdnano/PTCA/aptamer)...
September 8, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28844026/state-of-the-art-coronary-angiography
#15
Carlos Collet, Maik J Grundeken, Taku Asano, Yoshinobu Onuma, William Wijns, Patrick W Serruys
In the early days of coronary angiography, the precise quantification of luminal narrowing was challenging. The introduction of balloon angioplasty (percutaneous transluminal coronary angioplasty [PTCA]) by Andreas Grüntzig in 1977 was perhaps the greatest incentive to the development of quantitative coronary angiography (QCA). QCA has played a crucial role in evaluating interventional techniques and assessing the results of new technologies. With the advent of drug-eluting stents (DES), QCA metrics such as late lumen loss and diameter stenosis (restenosis) proved to be instrumental in assessing new technologies...
August 25, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28832097/effect-of-tandem-lesions-on-hemodynamic-parameters-an-experimental-study
#16
Adem Ilkay Diken, Adnan Yalçınkaya, Onur Hanedan, Eren Günertem, Emre Demir, Emir Erol
BACKGROUND AND AIM: The morphology and extensity of the stenotic lesion is crucial as well as the obstruction ratio. It is well known that the complexity of lesion has direct impact on endovascular treatment (PTCA/stent), however; different arrangement of the lesions is underestimated and not well studied. We sought to evaluate the hemodynamic effects of different stenotic lesion models and arrangements in vitro METHODS: Vascular circulation was simulated in vitro. Oxygenator, tubing set, polytetrahidroflouroethylene synthetic graft, pressure and flow rate sensors were used to build the simulation model...
August 23, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28792181/rescue-ptca-in-a-patient-with-single-coronary-anomaly
#17
Parveen Kumar, Hemant Chaturvedi, Ramakrsihna, Sanjeev Sharma
We present a case of rescue percutaneous coronary intervention (PCI) using right radial approach in a rare case of single coronary artery originating from the right sinus. Although these anomalies and stenosis of anomalous vessels have earlier been reported, treatment of atherosclerotic lesions by PCI has rarely been reported. There is a definite risk during PCI in patients with a single coronary ostium because dissection with the guiding catheter would result in a catastrophic event. Additionally, technical difficulties may occur due to the ostial configuration and course of the branch to be stented...
July 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28736085/low-cardiac-output-syndrome-in-the-postoperative-period-of-cardiac-surgery-profile-differences-in-clinical-course-and-prognosis-the-esbaga-study
#18
J L Pérez Vela, J J Jiménez Rivera, M Á Alcalá Llorente, B González de Marcos, H Torrado, C García Laborda, M D Fernández Zamora, F J González Fernández, J C Martín Benítez
OBJECTIVES: An analysis is made of the clinical profile, evolution and differences in morbidity and mortality of low cardiac output syndrome (LCOS) in the postoperative period of cardiac surgery, according to the 3 diagnostic subgroups defined by the SEMICYUC Consensus 2012. DESIGN: A multicenter, prospective cohort study was carried out. SETTING: ICUs of Spanish hospitals with cardiac surgery. PATIENTS: A consecutive sample of 2,070 cardiac surgery patients was included, with the analysis of 137 patients with LCOS...
July 20, 2017: Medicina Intensiva
https://www.readbyqxmd.com/read/28707263/delivery-of-viral-vectors-for-gene-therapy-in-intimal-hyperplasia-and-restenosis-in-atherosclerotic-swine
#19
REVIEW
Sannette Hall, Devendra K Agrawal
Cardiovascular diseases including atherosclerosis are a major financial and health burden globally. Inflammation associated with atherosclerosis results in the development of plaques that can rupture causing thrombosis, stroke, or death. The most widely used treatment for the removal of atherosclerotic plaques is percutaneous transluminal coronary angioplasty (PTCA) with or without stenting. Although this is a safer and minimally invasive method, restenosis and intimal hyperplasia after interventional procedure remains a major hurdle and more refined approaches are needed...
July 13, 2017: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/28689986/quaternion-based-study-of-angular-velocity-of-the-cardiac-vector-during-myocardial-ischaemia
#20
Pablo Daniel Cruces, Pedro David Arini
BACKGROUND: Early detection of acute ischaemia through non-invasive methods remains a challenge in health research. Ischaemic condition caused by a decrease in the blood supply in a cardiac region induces hypoxia and metabolic abnormalities that contribute to the electrical instability of the heart and to the development of slow conduction in damaged tissue. METHODS: Herein, a percutaneous transluminal coronary angiography (PTCA) is considered as a model of supply ischaemia...
December 1, 2017: International Journal of Cardiology
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