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glaucoma compliance

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https://www.readbyqxmd.com/read/28617721/analysis-of-a-physician-led-team-based-care-model-for-the-treatment-of-glaucoma
#1
Nelson S Winkler, Gena M Damento, Sunil S Khanna, David O Hodge, Cheryl L Khanna
PURPOSE: To determine the effect of a protocol for a new physician-led, team-based glaucoma care model implemented in 2008 at Mayo Clinic's campus in Rochester, Minnesota (MCR), to increase conformance with the American Academy of Ophthalmology (AAO) Preferred Practice Pattern guidelines for treatment of primary open-angle glaucoma. METHODS: Records of 591 patients with newly diagnosed glaucoma were assessed retrospectively for the completion of 9 AAO Preferred Practice Pattern recommended metrics including measured corneal thickness, intraocular pressure (IOP), cup to disk ratio, visual acuity, recorded IOP target, gonioscopy, fundus photos, ocular coherence tomography, and visual field in the 3 years before and 3 years after protocol implementation...
June 14, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28584204/decision-making-impairments-in-primary-angle-closure-glaucoma-patients
#2
Hui Pu, Yong Wang, Qiang Wei, Hui-Juan Ma, Pan-Pan Hu, Shou-Ling Li, Hong-Bo Pang, Yang-Hua Tian, Kai Wang
BACKGROUND: Primary angle-closure glaucoma (PACG) is a common eye disease and a common cause of blindness. Inappropriate medical decisions severely affect the prognosis. This study investigated decision-making under risk in PACG patients. METHODS: Thirty patients with first acute attack of PACG before surgery and thirty healthy controls were included in the study. Decision-making under risk was evaluated with the game of dice task (GDT). The results of Eysenck Personality Questionnaire (EPQ) and GDT between PACG patients and healthy controls were compared...
June 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28571839/-perception-of-glaucoma-and-therapeutic-adherence-a-multicenter-observational-study
#3
A Chiche, G Martin, E Brasnu de Cenival, A Rousseau, A Giocanti, A Fel, S Kallel, M Lombardi, P Hamard, C Baudouin, A Labbe
INTRODUCTION: The purpose of this study was to evaluate medication adherence of glaucoma patients through the "Glaucoma treatment compliance assessment tool (GTCAT)" questionnaire and to correlate the results with clinical parameters. PATIENTS AND METHODS: This multicenter prospective observational study was performed in the Département hospitalo-universitaire (DHU) Sight Restore, Paris, France. All patients had been followed for chronic open angle glaucoma (COAG) for at least 3 years...
May 29, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28525561/decade-long-profile-of-imaging-biomarker-use-in-ophthalmic-clinical-trials
#4
Edoardo Villani, Domenico Massaro, Matteo Scaramuzzi, Pedram Hamrah, Felipe A Medeiros, Paolo Nucci
Purpose: The purpose of this study was to investigate the use of imaging biomarkers in published clinical trials (CTs) in ophthalmology and its eventual changes during the past 10 years. Methods: We sampled from published CTs in the fields of cornea, retina, and glaucoma between 2005-2006 and 2015-2016. Data collected included year of publication, phase, subspecialty, location, compliance with Consolidated Standards for Reporting Trials, impact factor, presence and use of imaging biomarkers (diagnostic, prognostic and predictive; primary and secondary surrogate endpoints), and use of centralized reading centers...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28404532/cost-effectiveness-and-cost-utility-of-community-screening-for-glaucoma-in-urban-india
#5
Denny John, Rajul Parikh
OBJECTIVES: Population-based screening for glaucoma has been demonstrated to be cost-effective if targeted at high-risk groups such as older adults and those with a family history of glaucoma, and through use of a technician for conducting initial assessment rather than a medical specialist. This study attempts to investigate the cost-effectiveness of a hypothetical community screening and subsequent treatment programme for glaucoma in comparison with current practice (i.e. with no screening programme but with some opportunistic case finding) in the urban areas of India...
July 2017: Public Health
https://www.readbyqxmd.com/read/28356898/novel-pharmacologic-candidates-for-treatment-of-primary-open-angle-glaucoma
#6
REVIEW
Louise J Lu, James C Tsai, Ji Liu
Primary open-angle glaucoma (OAG) affects approximately 45 million people worldwide and more than 2.5 million people aged 40 years or older in the United States. Pharmacologic treatment for glaucoma is directed towards lowering intraocular pressure (IOP) to slow disease progression and delay visual field loss. Current medical treatment options for the lowering of IOP include the following classes of topical medications: beta-adrenergic antagonists, alpha-adrenergic agonists, cholinergic agonists, carbonic anhydrase inhibitors, and prostaglandin analogs...
March 2017: Yale Journal of Biology and Medicine
https://www.readbyqxmd.com/read/28302155/a-prospective-randomised-placebo-controlled-double-masked-three-armed-multicentre-phase-ii-iii-trial-for-the-study-of-a-topical-treatment-of-ischaemic-central-retinal-vein-occlusion-to-prevent-neovascular-glaucoma-the-strong-study-study-protocol-for-a-randomised
#7
Katrin Lorenz, Yvonne Scheller, Katharina Bell, Franz Grus, Katharina A Ponto, Felix Bock, Claus Cursiefen, Jens Flach, Marta Gehring, Tunde Peto, Rufino Silva, Yossi Tal, Norbert Pfeiffer
BACKGROUND: Neovascular glaucoma (NVG) is rare, comprising only 3.9% of all glaucoma cases. The most common cause of NVG is ischaemic central retinal vein occlusion (iCRVO). NVG frequently results in blindness and painful end-stage glaucomatous damage leading to the need for enucleation. Currently, there is no preventive therapy for NVG following iCRVO. Rescue treatments have severe drawbacks. Accordingly, there is a great need for preventing the often visually devastating outcomes of NVG...
March 16, 2017: Trials
https://www.readbyqxmd.com/read/28260356/-focus-on-popular-science-education-of-glaucoma-and-reduce-glaucomatous-low-vision-and-blindness
#8
X H Sun
The prevention of blindness caused by glaucoma is a difficult task. In order to accomplish the task better, we need the participation of whole society and popularize relevant medical knowledge. Popular science and related knowledge of glaucoma are needed to the people especially for high risk population. If people know glaucoma better and actively join the screening of glaucoma, we can find and diagnose glaucoma earlier, avoid late treatment and reduce the glaucomatous visual function impairment. For patients who had been diagnosed with glaucoma, they should aware and accept new medical concept and technique through systemic popular science education...
February 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28251091/a-cross-sectional-study-on-compliance-with-topical-glaucoma-medication-and-its-associated-socioeconomic-burden-for-a-chinese-population
#9
Man-Hin Lui, Jason Chun Ho Lam, Yi Lee Kwong, Tak Siu Wong, Pak Long Cheung, Sherri Shun Yan Lai, Pak Lun Yuen, Wai Yiu Lam, Ho Yan Chan, Yiu Fai Wong, Jimmy Shiu Ming Lai, Kendrick Co Shih
AIM: To estimate the overall drug compliance for local Chinese glaucoma patients on long-term topical treatment. METHODS: This was a retrospective cross-sectional study. Fifty-seven primary glaucoma patients from the subspecialty clinic of a publicly-funded tertiary care hospital in Hong Kong completed a questionnaire on compliance with topical glaucoma medication, attitude towards glaucoma and therapy and vision related quality of life. Noncompliance was defined as reporting missing more than or equal to 10% of the prescribed topical glaucoma medication during the 2wk immediately prior to the consultation...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28181960/barriers-to-glaucoma-medication-compliance-among-veterans-dry-eye-symptoms-and-anxiety-disorders
#10
Jack Stringham, Noy Ashkenazy, Anat Galor, Sarah R Wellik
OBJECTIVE: To identify barriers to compliance of medical treatment for glaucoma among veterans. METHODS: Patients with glaucoma from the Miami Veterans Affairs Eye Clinic (n=74) filled out a 63-question survey regarding dry eye symptoms, concurrent systemic disease, and medications. The association between glaucoma medical compliance was defined as self-reported adherence to drop regimens greater than 75% of the time. RESULTS: Eighty percent of veterans (n=59) reported compliance with glaucoma therapy...
January 6, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/27994392/bottle-characteristics-of-topical-international-glaucoma-medications-versus-local-brands-in-saudi-arabia
#11
COMPARATIVE STUDY
Nasser Al-Jumaian, Rizwan Malik, Rajiv Khandekar, Abdullah Al-Humaidan, Rana Al-Madany, Reham Al-Qahtani, Ahmed Altowairqi, Abdulwahab Al-Theeb, Babar Zaman, Leyla Al-Djasim, E Randy Craven, Deepak P Edward
WHAT IS KNOWN AND OBJECTIVE: Physical bottle characteristics differ of brand name topical glaucoma medications and local generic equivalents. This study compares the bottle characteristics of international topical glaucoma brands versus local brands from the Kingdom of Saudi Arabia. METHODS: Data were collected on bottle drum volume, drop volume, bottle squeezability, bottle tip diameter, labels and instructions, cap color coding, and clarity of the drug label. Density-based calculations of drops in bottle volume were assessed using an analytic balance...
October 2016: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/27955999/neuroprotection-for-glaucoma-requirements-for-clinical-translation
#12
Leonard A Levin, Megan E Crowe, Harry A Quigley
Within the field of glaucoma research, neuroprotection is defined as slowing the functional loss in glaucoma by a mechanism independent of lowering of intraocular pressure. There is currently a great potential for research surrounding neuroprotection as it relates to glaucoma. Anatomical targets for neuroprotection should focus on upstream rather than downstream factors, and could include any part of the retinal ganglion cell, the glia, especially astrocytes or Muller cells, and vasculature. The great number of anatomical targets is exceeded only by the number of possible biochemical pathways and potential treatments...
April 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/27938956/improvement-of-the-visual-field-index-in-clinical-glaucoma-care
#13
Shawn L Cohen, Aaron I Rosen, Xianming Tan, Frederick A A Kingdom
OBJECTIVE: This article investigates the prevalence and attributes of patients with open-angle glaucoma who exhibit improvement of visual field loss in a clinical setting. DESIGN: We conducted a retrospective chart review of patients in a clinical glaucoma practice. PARTICIPANTS: We identified 719 glaucoma patients with at least 5 SITA strategy visual field tests and a minimum continuous follow-up period of 5 years. METHODS: The change in the slope of the visual field index (VFI) over time was illustrated using histogram analysis for the study eye with the worst VFI at baseline...
December 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/27928879/minimally-invasive-glaucoma-surgery-as-primary-stand-alone-surgery-for-glaucoma
#14
REVIEW
Nathan M Kerr, Jing Wang, Keith Barton
Recently, many new devices and procedures have been developed to lower intraocular pressure in a less invasive and purportedly safer manner than traditional glaucoma surgery. These new devices might encourage an earlier transition to surgery and reduce the long-term commitment to topical glaucoma medications with their associated compliance and intolerance issues. Although often seen as an adjunct to cataract surgery, a growing body of evidence suggests that primary minimally invasive glaucoma surgery may be a viable initial treatment option...
May 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/27898580/resident-compliance-with-the-american-academy-of-ophthalmology-preferred-practice-patterns-for-primary-open-angle-glaucoma-suspect
#15
Melanie Mihlstin, Mark S Juzych, Heidi T Kromrei, Frank S Hwang, Jia Yin
PURPOSE: To study resident compliance with the American Academy of Ophthalmology (AAO) Preferred Practice Patterns (PPPs) for primary open-angle glaucoma suspect (POAGS) in a resident ophthalmology clinic. PATIENTS AND METHODS: Two hundred charts were selected for analysis of adult patients with the International Classification of Diseases diagnosis code for POAGS during their initial visit between November 2, 2010 and May 6, 2014 at the Kresge Eye Institute resident clinic...
December 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27729348/ophthalmologists-practice-patterns-and-challenges-in-achieving-optimal-management-for-glaucoma-in-nigeria-results-from-a-nationwide-survey
#16
Fatima Kyari, Winifred Nolan, Clare Gilbert
PURPOSE OF THE STUDY: Glaucoma, a chronic non-communicable disease, and leading cause of irreversible blindness worldwide is a public health problem in Nigeria, with a prevalence of 5.02% in people aged ≥40 years. The purpose of this nationwide survey was to assess Nigerian ophthalmologists' practice patterns and their constraints in managing glaucoma. STUDY DESIGN: Ophthalmologists were sent a semistructured questionnaire on how they manage glaucoma, their training in glaucoma care, where they practice, their access to equipment for diagnosis and treatment, whether they use protocols and the challenges they face in managing patients with glaucoma...
October 11, 2016: BMJ Open
https://www.readbyqxmd.com/read/27703324/preservative-free-bimatoprost-0-03-timolol-0-5-fixed-combination-in-patients-with-glaucoma-in-clinical-practice
#17
Stefan Pfennigsdorf, Peter Eschstruth, Stefan Häsemeyer, Cord Feuerhake, Gerrett Brief, Ioana Grobeiu, Andrew Shirlaw
PURPOSE: The aim of this study was to evaluate the efficacy and tolerability of, and compliance to, preservative-free (PF), fixed-combination (FC) bimatoprost 0.03%/timolol 0.5% in patients with primary open-angle glaucoma or ocular hypertension in a clinical practice setting. PATIENTS AND METHODS: This open-label study observed patients switched to PF FC bimatoprost 0.03%/timolol 0.5% due to insufficient intraocular pressure (IOP) control on previous therapies...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27672307/preservative-free-bimatoprost-0-03-in-patients-with-primary-open-angle-glaucoma-or-ocular-hypertension-in-clinical-practice
#18
Lutz E Pillunat, Peter Eschstruth, Stefan Häsemeyer, Ulrich Thelen, Christian Foja, Richard Leaback, Stefan Pfennigsdorf
BACKGROUND: Intraocular pressure (IOP)-lowering medications for primary open-angle glaucoma and ocular hypertension commonly contain preservatives that can cause ocular surface damage in many patients. The purpose of this study was to evaluate the efficacy and tolerability of, and compliance to, preservative-free (PF) bimatoprost 0.03% in patients with primary open-angle glaucoma or ocular hypertension (IOP ≥18 mmHg) in a clinical practice setting. METHODS: This open-label study observed patients who were switched to PF bimatoprost 0...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27487608/challenges-in-the-management-of-glaucoma-in-a-developing-country-a-qualitative-study-of-providers-perspectives
#19
B J Adekoya, F G Adepoju, K F Moshood, A H Balarabe
BACKGROUND: Glaucoma management is challenging to patients as well as to the eye care providers. The study is aimed at describing the challenges faced by providers using qualitative methods. METHODS: In-depth interviews were conducted with selected Ophthalmologists and resident doctors in ophthalmology at centres offering medical and surgical glaucoma services in Lagos state, Nigeria, according to established qualitative methods. This was done using semi-structured, open ended questions to explore the providers' perspective on glaucoma burden, challenges in the management, surgery for glaucoma, acceptance of glaucoma surgery by patients, and recommendations for improving glaucoma services...
October 2015: Nigerian Journal of Medicine: Journal of the National Association of Resident Doctors of Nigeria
https://www.readbyqxmd.com/read/27456565/-reasons-for-intraocular-pressure-to-resist-hypotensive-therapy-in-glaucoma-patients
#20
A L Onishchenko, A V Kolbasko, M A Safronova, I N Isakov
AIM: To study the reasons of intraocular pressure (IOP) resistance to therapy in patients with glaucoma. MATERIAL AND METHODS: During the period 2011-2013 we examined 72 primary glaucoma patients (stage I-III), 44 women and 28 men, aged 49-87 years (65.2±2.5 years on average) referred by local ophthalmologists due to poor response to hypotensive therapy. RESULTS: We suggest that glaucoma should be regarded as resistant if, despite combination therapy with three antihypertensive drugs at optimal doses, IOP stays above the target...
May 2016: Vestnik Oftalmologii
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