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Prostate brachytherapy

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https://www.readbyqxmd.com/read/29782208/optimal-radical-therapy-for-localized-prostate-cancer-recreation-of-the-self-fulfilling-prophecy-with-combination-brachytherapy
#1
Daniel E Spratt, Peter R Carroll
No abstract text is available yet for this article.
May 21, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29764692/combined-high-dose-rate-brachytherapy-and-external-beam-radiotherapy-for-clinically-localised-prostate-cancer
#2
Iosif Strouthos, Georgios Chatzikonstantinou, Nikolaos Zamboglou, Natasa Milickovic, Sokratis Papaioannou, Dimitra Bon, Constantinos Zamboglou, Claus Rödel, Dimos Baltas, Nikolaos Tselis
PURPOSE: To report the clinical outcomes and treatment-related toxicities after combined high-dose-rate (HDR) brachytherapy (BRT) with external beam radiotherapy (EBRT) for patients with clinically localised high-risk prostate cancer. MATERIAL AND METHODS: Between 2008 and 2012, three hundred and three consecutive patients with organ-confined high-risk prostate cancer were treated with definitive radiotherapy consisting of HDR-BRT followed by supplemental EBRT. The transrectal 3D-ultrasound-based HDR-BRT boost consisted of two single-fraction implants of 10...
May 12, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29753523/testicular-transposition-in-children-undergoing-brachytherapy-for-bladder-and-or-prostate-rhabdomyosarcoma
#3
Guenolee de Lambert, Cyrus Chargari, Véronique Minard-Colin, Christine Haie-Meder, Florent Guérin, Hélène Martelli
BACKGROUND/PURPOSE: Fertility preservation is a major goal in treatment of children with cancer. We describe a new technique of testicular transposition (TT) in patients treated with pulse-dose-rate (PDR) brachytherapy as part of the multimodal conservative treatment of bladder neck and/or prostate rhabdomyosarcoma (BP RMS). METHODS: Medical records of consecutive patients treated between September 2016 and August 2017 were studied. These patients underwent a TT performed during BP RMS surgery by the same suprapubic incision...
April 13, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29743948/the-current-state-of-prostate-cancer-treatment-in-trinidad-and-tobago
#4
REVIEW
Satyendra Persaud, Maliza Persaud, Lester Goetz, Dylan Narinesingh
Prostate cancer mortality in the Caribbean region is among the highest in the world and prostate cancer is the most common cancer in Trinidad and Tobago. There is a two-tiered healthcare system in Trinidad and Tobago, and prostate cancer related issues account for a significant percentage of urologists' workload. Delivery of care is sometimes constrained by limited financial resources. Prostate-specific antigen testing is widely available but there is no national guideline. Treatment options available include active surveillance, radical prostatectomy, external beam radiotherapy and brachytherapy...
2018: Ecancermedicalscience
https://www.readbyqxmd.com/read/29743538/which-technology-to-select-for-primary-focal-treatment-of-prostate-cancer-european-section-of-urotechnology-esut-position-statement
#5
REVIEW
Roman Ganzer, Vinodh Kumar Adithyaa Arthanareeswaran, Hashim U Ahmed, Andrea Cestari, Pascal Rischmann, Georg Salomon, Dogu Teber, Evangelos Liatsikos, Jens-Uwe Stolzenburg, Eric Barret
BACKGROUND: With growing interest in focal therapy (FT) of prostate cancer (PCa) there is an increasing armamentarium of treatment modalities including high-intensity focused ultrasound (HIFU), cryotherapy, focal laser ablation (FLA), irreversible electroporation (IRE), vascular targeted photodynamic therapy (VTP), focal brachytherapy (FBT) and stereotactic ablative radiotherapy (SABR). Currently there are no clear recommendations as to which of these technologies are appropriate for individual patient characteristics...
May 9, 2018: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/29732218/repair-of-recto-urethral-fistula-with-urethral-augmentation-by-buccal-mucosal-graft-and-gracilis-muscle-flap-interposition-our-experience
#6
Vikram Prabha, Vishal Kadeli
Introduction: Recto-urethral fistula (RUF) is a relatively rare surgical condition, the treatment of which is quite challenging. There are many causes of RUF, but 60% of them are iatrogenic following open prostatectomies, radiotherapy, brachytherapy, urethral instrumentation etc. We present a series of six cases treated at our institution. Material and methods: A retrospective study of all six patients with recto-urethral fistula treated at our centre between 2011 and 2016 was performed...
2018: Central European Journal of Urology
https://www.readbyqxmd.com/read/29731428/three-piece-inflatable-penile-prosthesis-placement-following-pelvic-radiation-technical-considerations-and-contemporary-outcomes
#7
Jeffrey Loh-Doyle, Mukul B Patil, Zein Nakhoda, Nima Nassiri, Wesley Yip, Kevin Wayne, Leo Doumanian, Stuart D Boyd
BACKGROUND: Pelvic radiation is a known risk factor for the development and progression of erectile dysfunction. When medical therapy fails, the 3-piece inflatable penile prosthesis (IPP) can offer patients a definitive treatment option. Because of radiation-induced vascular changes and tissue fibrosis, a careful surgical approach is necessary to avoid intraoperative complications and attain successful outcomes. Despite its widespread use in prostate cancer treatment, there are no contemporary studies examining the effects that pelvic radiation can have on 3-piece IPP placement and device survival...
May 3, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29726091/factors-influencing-long-term-urinary-symptoms-following-prostate-brachytherapy
#8
Nelson N Stone, Jared S Winoker, Steven A Kaplan, Richard G Stock
OBJECTIVES: To determine which patient and treatment related factors were associated with increased AUA symptom score (AUASS) in men who presented with minimal symptoms prior to treatment for prostate cancer by permanent seed implantation. MATERIALS AND METHODS: Of 1842 men with a minimum follow-up of 5 years (mean 9.4) 1110 (60.3%) had initial AUASS of 0-7 and were treated with BT alone (n=491) or BT with hormone therapy (NHT) and or external beam irradiation (EBRT, n=619)...
May 3, 2018: BJU International
https://www.readbyqxmd.com/read/29709315/salvage-hdr-brachytherapy-multiple-hypothesis-testing-versus-machine-learning-analysis
#9
Gilmer Valdes, Albert J Chang, Yannet Interian, Kenton Owen, Shane T Jensen, Lyle H Ungar, Adam Cunha, Timothy D Solberg, I-Chow Hsu
PURPOSE: Salvage high-dose-rate brachytherapy (sHDRB) is a treatment option for recurrences after prior radiation therapy. However, only approximately 50% of patients benefit, with the majority of second recurrences after salvage brachytherapy occurring distantly. Therefore, identification of characteristics that can help select patients who may benefit most from sHDRB is critical. Machine learning may be used to identify characteristics that predict outcome following sHDRB. We aimed to use machine learning to identify patient characteristics associated with biochemical failure (BF) following prostate sHDRB...
March 13, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29700974/interpolation-to-define-clinical-tumor-stage-in-prostate-cancer-using-clinical-description-of-digital-rectal-examination
#10
Sue M Evans, Declan G Murphy, Ian D Davis, Shomik Sengupta, Ehsan Zare Borzeshi, Fanny Sampurno, Jeremy L Millar
AIM: This study aims to assess characteristics of patients with prostate cancer for whom clinical T stage category (cT) was not documented in the medical record and assess whether specialists had concordant conclusions regarding cT based on digital rectal examination (DRE) notes. METHODS: Data from the Prostate Cancer Outcome Registry - Victoria (PCOR-Vic) were interrogated. Four specialists independently assigned cT to DRE notes. Words, or part thereof, associated with agreement between clinicians were identified...
April 27, 2018: Asia-Pacific Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29699921/monte-carlo-study-of-out-of-field-exposure-in-carbon-ion-radiotherapy-with-a-passive-beam-organ-doses-in-prostate-cancer-treatment
#11
Shunsuke Yonai, Naruhiro Matsufuji, Keiichi Akahane
PURPOSE: The aim of this work was to estimate typical dose equivalents to out-of-field organs during carbon-ion radiotherapy (CIRT) with a passive beam for prostate cancer treatment. Additionally, sensitivity analyses of organ doses for various beam parameters and phantom sizes were performed. METHODS: Because the CIRT out-of-field dose depends on the beam parameters, the typical values of those parameters were determined from statistical data on the target properties of patients who received CIRT at the Heavy-Ion Medical Accelerator in Chiba (HIMAC)...
April 23, 2018: Physica Medica: PM
https://www.readbyqxmd.com/read/29685521/prospective-evaluation-of-fluciclovine-18-f-pet-ct-and-mri-in-detection-of-recurrent-prostate-cancer-in-non-prostatectomy-patients
#12
Oladunni Akin-Akintayo, Funmilayo Tade, Pardeep Mittal, Courtney Moreno, Peter T Nieh, Peter Rossi, Dattatraya Patil, Raghuveer Halkar, Baowei Fei, Viraj Master, Ashesh B Jani, Hiroumi Kitajima, Adeboye O Osunkoya, Claudia Ormenisan-Gherasim, Mark M Goodman, David M Schuster
PURPOSE: To investigate the disease detection rate, diagnostic performance and interobserver agreement of fluciclovine (18 F) PET-CT and multiparametric magnetic resonance imaging (mpMR) in recurrent prostate cancer. METHODS: Twenty-four patients with biochemical failure after non-prostatectomy definitive therapy, 16/24 of whom had undergone brachytherapy, underwent fluciclovine PET-CT and mpMR with interpretation by expert readers blinded to patient history, PSA and other imaging results...
May 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/29680008/secondary-mucinous-carcinoma-of-the-prostate-after-low-dose-rate-brachytherapy
#13
Sonja C Murchison, Mildred B Martens, Pauline Truong, Abraham Alexander
Radiation induced malignancy (RIM) after treatment for prostate cancer is well documented after external beam irradiation, but less so in the setting of brachytherapy. We report a case of mucinous adenocarcinoma of the prostate, consistent with a RIM, which developed 12 years after low dose rate brachytherapy for low risk prostate adenocarcinoma. Diagnostic and therapeutic considerations of RIM are discussed. As long term survivors are followed in the community by primary care physicians and urologists, awareness of RIM as a potential late effect of brachytherapy is important to ensure that cases are diagnosed and managed appropriately...
April 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29673922/patient-reported-outcomes-after-treatment-for-clinically-localized-prostate-cancer-a-systematic-review-and-meta-analysis
#14
REVIEW
Mónica Ávila, Laila Patel, Silvia López, Laura Cortés-Sanabria, Olatz Garin, Àngels Pont, Ferran Ferrer, Ana Boladeras, Victor Zamora, Sophie Fosså, Anne H Storås, Martin Sanda, Vicky Serra-Sutton, Montse Ferrer
BACKGROUND: The aim of this systematic review is to assess the impact of primary treatments with curative intention in patients with localized prostate cancer, measured with Patient-Reported Outcomes (PROs), and to examine differences among modalities within treatments. METHODS: We conducted a systematic literature search for January 2005-March 2017 following PRISMA guidelines, including longitudinal studies measuring disease-specific PROs in localized prostate cancer patients with a follow-up from pre- to post-treatment (≥1 year)...
April 3, 2018: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/29667307/reduction-of-seed-motion-using-a-bio-absorbable-polymer-coating-during-permanent-prostate-brachytherapy-using-a-mick-applicator-technique
#15
Gregory R Warrell, Yan Xing, Tarun K Podder, Bryan J Traughber, Rodney J Ellis
PURPOSE: The addition of a braided bio-absorbable vicryl coating to the surface of radioactive seeds used for low dose rate (LDR) prostate brachytherapy is intended to reduce the incidence of seed movement and migration. Here, we present a single-institution study of the frequency and severity of seed slippage (initial seed movement) of coated seeds in comparison with uncoated seeds. METHODS: Forty-seven patients received permanent prostate brachytherapy, with either coated (n = 26) or uncoated (n = 21) seeds...
April 17, 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29663462/survival-benefit-of-local-versus-no-local-treatment-for-metastatic-prostate-cancer-impact-of-baseline-psa-and-metastatic-substages
#16
Raisa S Pompe, Derya Tilki, Felix Preisser, Sami-Ramzi Leyh-Bannurah, Marco Bandini, Michele Marchioni, Philipp Gild, Zhe Tian, Nicola Fossati, Luca Cindolo, Shahrokh F Shariat, Hartwig Huland, Markus Graefen, Alberto Briganti, Pierre I Karakiewicz
BACKGROUND: To test whether local treatment (LT), namely radical prostatectomy (RP) or brachytherapy (BT) still confers a survival benefit versus no local treatment (NLT), when adjusted for baseline PSA (bPSA). To further examine whether the effect of LT might be modulated according to bPSA and M1 substages. METHODS: Of 13 906 mPCa patients within the SEER (2004-2014), 375 underwent RP, 175 BT, and 13 356 NLT. Multivariable competing risks regression (MVA CRR) analyses after 1:2 propensity score matching assessed the impact of LT versus NLT on cancer specific mortality (CSM)...
April 16, 2018: Prostate
https://www.readbyqxmd.com/read/29662542/meta-analysis-of-studies-comparing-oncologic-outcomes-of-radical-prostatectomy-and-brachytherapy-for-localized-prostate-cancer
#17
Gabriele Cozzi, Gennaro Musi, Roberto Bianchi, Danilo Bottero, Antonio Brescia, Antonio Cioffi, Giovanni Cordima, Maurizio Delor, Ettore Di Trapani, Matteo Ferro, Deliu Victor Matei, Andrea Russo, Francesco Alessandro Mistretta, Ottavio De Cobelli
Background: The aim of this study was to compare oncologic outcomes of radical prostatectomy (RP) with brachytherapy (BT). Methods: A literature review was conducted according to the 'Preferred reporting items for systematic reviews and meta-analyses' (PRISMA) statement. We included studies reporting comparative oncologic outcomes of RP versus BT for localized prostate cancer (PCa). From each comparative study, we extracted the study design, the number and features of the included patients, and the oncologic outcomes expressed as all-cause mortality (ACM), PCa-specific mortality (PCSM) or, when the former were unavailable, as biochemical recurrence (BCR)...
November 2017: Therapeutic Advances in Urology
https://www.readbyqxmd.com/read/29661719/rectal-ulcer-and-pseudomalignant-epithelial-changes-after-prostate-seed-brachytherapy-a-rare-complication-with-a-diagnostic-pitfall
#18
Hwajeong Lee, Natallia Sheuka, Osama El-Kadi, Brian P Murray, Hugh A Fisher, Bhaskar V S Kallakury, Edward C Lee, Ann Boguniewicz, Timothy A Jennings
BACKGROUND: Implant brachytherapy (IBT) is a well-recognized treatment modality for early stage prostate cancer. Rectal ulcer and rectourethral fistula complicating IBT may cause an alteration of the normal anatomic landmarks. In this context, pseudomalignant radiation-induced changes within prostatic epithelium may be misinterpreted as a primary rectal malignancy. Such challenging and misleading findings have not been described, and may not be recognized as such. MATERIALS AND METHODS: We present the clinical and pathologic aspects of two patients who underwent IBT for low stage prostate cancer that was complicated by deep rectal ulcer...
April 4, 2018: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/29659976/a-novel-radiation-shielding-undergarment-using-tungsten-functional-paper-for-patients-with-permanent-prostate-brachytherapy
#19
Masahiro Inada, Hajime Monzen, Kenji Matsumoto, Mikoto Tamura, Takafumi Minami, Kiyoshi Nakamatsu, Yasumasa Nishimura
Tungsten functional paper (TFP) is a paper-based radiation-shielding material, which is lead-free and easy to cut. We developed a radiation protection undergarment using TFP for prostate cancer patients treated with permanent 125I seed implantation (PSI). The aim of this study was to evaluate the shielding ability of the undergarment with respect to household contacts and members of the public. Between October 2016 and April 2017, a total of 10 prostate cancer patients treated with PSI were enrolled in this prospective study...
April 11, 2018: Journal of Radiation Research
https://www.readbyqxmd.com/read/29651796/oncological-impact-of-neoadjuvant-hormonal-therapy-on-permanent-iodine-125-seed-brachytherapy-in-patients-with-low-and-intermediate-risk-prostate-cancer
#20
Atsushi Takamoto, Ryuta Tanimoto, Kensuke Bekku, Motoo Araki, Takuya Sadahira, Koichiro Wada, Shin Ebara, Norihisa Katayama, Hiroyuki Yanai, Yasutomo Nasu
OBJECTIVES: To determine whether neoadjuvant hormonal therapy improves oncological outcomes of patients with localized prostate cancer treated with permanent brachytherapy. METHODS: Between January 2004 and November 2014, 564 patients underwent transperineal ultrasonography-guided permanent iodine-125 seed brachytherapy. We retrospectively analyzed low- or intermediate-risk prostate cancer based on the National Comprehensive Cancer Network guidelines. The clinical variables were evaluated for influence on biochemical recurrence-free survival, progression-free survival, cancer-specific survival and overall survival...
April 12, 2018: International Journal of Urology: Official Journal of the Japanese Urological Association
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