keyword
MENU ▼
Read by QxMD icon Read
search

Spaced learning

keyword
https://www.readbyqxmd.com/read/29456486/generic-hrtfs-may-be-good-enough-in-virtual-reality-improving-source-localization-through-cross-modal-plasticity
#1
Christopher C Berger, Mar Gonzalez-Franco, Ana Tajadura-Jiménez, Dinei Florencio, Zhengyou Zhang
Auditory spatial localization in humans is performed using a combination of interaural time differences, interaural level differences, as well as spectral cues provided by the geometry of the ear. To render spatialized sounds within a virtual reality (VR) headset, either individualized or generic Head Related Transfer Functions (HRTFs) are usually employed. The former require arduous calibrations, but enable accurate auditory source localization, which may lead to a heightened sense of presence within VR. The latter obviate the need for individualized calibrations, but result in less accurate auditory source localization...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29451898/integrating-linear-optimization-with-structural-modeling-to-increase-hiv-neutralization-breadth
#2
Alexander M Sevy, Swetasudha Panda, James E Crowe, Jens Meiler, Yevgeniy Vorobeychik
Computational protein design has been successful in modeling fixed backbone proteins in a single conformation. However, when modeling large ensembles of flexible proteins, current methods in protein design have been insufficient. Large barriers in the energy landscape are difficult to traverse while redesigning a protein sequence, and as a result current design methods only sample a fraction of available sequence space. We propose a new computational approach that combines traditional structure-based modeling using the Rosetta software suite with machine learning and integer linear programming to overcome limitations in the Rosetta sampling methods...
February 16, 2018: PLoS Computational Biology
https://www.readbyqxmd.com/read/29449648/the-role-of-disease-linked-residue-glutamine-913-in-support-of-the-structure-and-function-of-the-human-electrogenic-sodium-bicarbonate-cotransporter-nbce1-a
#3
Evan J Myers, Aniko Marshall, Mark D Parker
Mutations in the sodium bicarbonate cotransporter NBCe1 (SLC4A4) cause proximal renal tubular acidosis (pRTA). We recently described a novel pRTA mutation p.Gln913Arg (Q913R), inherited in compound heterozygous form with p.Arg510His (R510H). Q913R causes intracellular retention of NBCe1 and a 'gain of function' Cl - leak. To learn more about the importance of glutamine at position 913, we substituted a variety of alternative amino-acid residues (Cys, Glu, Lys, Leu, Ser) at position 913. Studying cRNA-injected Xenopus oocytes by voltage clamp, we find that most de novo mutants exhibit close-to-normal NBCe1 activity; only Q913K expresses a Cl - leak...
February 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29449509/predicting-reaction-performance-in-c-n-cross-coupling-using-machine-learning
#4
Derek T Ahneman, Jesús G Estrada, Shishi Lin, Spencer D Dreher, Abigail G Doyle
Machine learning methods are becoming integral to scientific inquiry in numerous disciplines. Here we demonstrate that machine learning can be used to predict the performance of a synthetic reaction in multidimensional chemical space using data obtained via high-throughput experimentation. We created scripts to compute and extract atomic, molecular, and vibrational descriptors for the components of a palladium-catalyzed Buchwald-Hartwig cross-coupling of aryl halides with 4-methylaniline in the presence of various potentially inhibitory additives...
February 15, 2018: Science
https://www.readbyqxmd.com/read/29445188/daily-circadian-misalignment-impairs-human-cognitive-performance-task-dependently
#5
Sarah L Chellappa, Christopher J Morris, Frank A J L Scheer
Shift work increases the risk for human errors, such that drowsiness due to shift work has contributed to major industrial disasters, including Space Shuttle Challenger, Chernobyl and Alaska Oil Spill disasters, with extraordinary socio-economical costs. Overnight operations pose a challenge because our circadian biology inhibits cognitive performance at night. Yet how the circadian system modulates cognition over multiple days under realistic shift work conditions remains to be established. Importantly, because task-specific cognitive brain regions show different 24-h circadian dynamics, we hypothesize that circadian misalignment impacts cognition task-dependently...
February 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29440943/state-of-the-art-of-robotic-surgery-related-to-vision-brain-and-eye-applications-of-newly-available-devices
#6
REVIEW
Raffaele Nuzzi, Luca Brusasco
Background: Robot-assisted surgery has revolutionized many surgical subspecialties, mainly where procedures have to be performed in confined, difficult to visualize spaces. Despite advances in general surgery and neurosurgery, in vivo application of robotics to ocular surgery is still in its infancy, owing to the particular complexities of microsurgery. The use of robotic assistance and feedback guidance on surgical maneuvers could improve the technical performance of expert surgeons during the initial phase of the learning curve...
2018: Eye and Brain
https://www.readbyqxmd.com/read/29435644/innovative-real-csf-leak-simulation-model-for-rhinology-training-human-cadaveric-design
#7
Abdulaziz A AlQahtani, Abeer A Albathi, Othman M Alhammad, Abdulkarim S Alrabie
OBJECTIVE: To study the feasibility of designing a human cadaveric simulation model of real CSF leak for rhinology training. METHOD: The laboratory investigation took place at the surgical academic center of Prince Sultan Military Medical City between 2016 and 2017. Five heads of human cadaveric specimens were cannulated into the intradural space through two frontal bone holes. Fluorescein-dyed fluid was injected intracranialy, then endoscopic endonasal iatrogenic skull base defect was created with observation of fluid leak, followed by skull base reconstruction...
February 12, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29434042/maximizing-the-information-learned-from-finite-data-selects-a-simple-model
#8
Henry H Mattingly, Mark K Transtrum, Michael C Abbott, Benjamin B Machta
We use the language of uninformative Bayesian prior choice to study the selection of appropriately simple effective models. We advocate for the prior which maximizes the mutual information between parameters and predictions, learning as much as possible from limited data. When many parameters are poorly constrained by the available data, we find that this prior puts weight only on boundaries of the parameter space. Thus, it selects a lower-dimensional effective theory in a principled way, ignoring irrelevant parameter directions...
February 6, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29433996/gelatin-thoracic-paravertebral-teaching-model-for-placement-of-a-continuous-infusion-catheter-in-the-extrathoracic-paravertebral-space
#9
Shruti Sevak, Ashley Woodfin, Zachary Hothem, Rose Callahan, James Robbins, Kathryn Ziegler
OBJECTIVE: Our aim was to develop an ultrasound-guided training curriculum for continuous infusion catheter placement in the paravertebral space and to create a gelatin thoracic spine-rib model for use in this training. We sought to create a model that was inexpensive and reusable such that multiple participants could use one model during training. DESIGN: The model was prepared by embedding a firm foam thoracic spine replica with bilateral attached ribs into an opaque gelatin mixture...
February 9, 2018: Journal of Surgical Education
https://www.readbyqxmd.com/read/29433950/implementation-and-evaluation-of-a-therapeutic-patient-education-programme-during-a-clinical-trial-in-yaound%C3%A3-cameroon-trial-anrs-12286-mobidip
#10
Adrien Galy, Laura Ciaffi, Geraldine Manirakiza Mberyo, Pretty Mbouyap, Hermine Abessolo, Roselyne Toby, Frida Essomba, Geneviève Lamarre, Angeline Bikié, Olga Bell, Sinata Koulla-Shiro, Eric Delaporte
OBJECTIVES: High adherence is needed to maintain antiretroviral therapy efficacy. Few attempts at therapeutic patient education (TPE) have been made in sub-Saharan Africa. We describe patients' achievements before intervention and identified needs, TPE programme implementation and evaluation, and patients' satisfaction. METHODS: The TPE programme was proposed to patients in the ANRS-12286/MOBIDIP trial. Beforehand, a directory of competences to manage HIV infection was designed...
February 1, 2018: Patient Education and Counseling
https://www.readbyqxmd.com/read/29433728/bronchoscopy-education-an-experiential-learning-theory-perspective
#11
REVIEW
Septimiu D Murgu, Jonathan S Kurman, Omar Hasan
Bronchoscopy programs implementing the experiential learning model address different learning styles. Problem-based learning improves knowledge retention, critical decision making, and communication. These modalities are preferred by learners and contribute to their engagement, in turn leading to durable learning. Follow-up after live events is warranted through spaced education strategies. The objectives of this article are to (1) summarize and illustrate the implementation of experiential learning theory for bronchoscopy courses, (2) discuss the flipped classroom model and problem-based learning, (3) illustrate bronchoscopy checklists implementation in simulation, and (4) discuss the importance of feedback and spaced learning for bronchoscopy education programs...
March 2018: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/29430212/deep-attractor-network-for-single-microphone-speaker-separation
#12
Zhuo Chen, Yi Luo, Nima Mesgarani
Despite the overwhelming success of deep learning in various speech processing tasks, the problem of separating simultaneous speakers in a mixture remains challenging. Two major difficulties in such systems are the arbitrary source permutation and unknown number of sources in the mixture. We propose a novel deep learning framework for single channel speech separation by creating attractor points in high dimensional embedding space of the acoustic signals which pull together the time-frequency bins corresponding to each source...
March 2017: Proceedings of the ... IEEE International Conference on Acoustics, Speech, and Signal Processing
https://www.readbyqxmd.com/read/29428432/supporting-doctors-as-healthcare-quality-and-safety-advocates-recommendations-from-the-associations-of-surgeons-in-training-asit
#13
C A Fleming, G Humm, J R Wild, H M Mohan, S T Hornby, R L Harries, J E F Fitzgerald, A J Beamish
BACKGROUND: As front-line healthcare staff, doctors in surgical training occupy a unique organisational space rotating through hospitals and services in which they witness first hand both good and bad practice. This puts trainees in a clear position to identify and raise patient safety issues, and to contribute to discussions regarding quality and safety improvement. However, there are a number of real and perceived barriers to trainees doing so. These include concerns about the impact on training assessments and career progression, and uncertainty about the appropriate route...
February 8, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29428359/laparoscopic-simulator-for-pediatric-ureteral-reimplantation-lap-spur-following-the-lich-gregoir-technique
#14
Carolina Millán, Mercedes Rey, Manuel Lopez
OBJECTIVE: Acquiring surgical skills requires regular practice. Medical evidence supports that these skills can be learned outside the operating room (OR). The aim of the current study was to describe the first laparoscopic simulator for ureteral reimplantation (LAP-SPUR) following Lich- Gregoir technique. MATERIALS AND METHODS: LAP-SPUR was manufactured using reusable and disposable materials. The technique can be summarized in the following five steps: (1) a transperitoneal approach; (2) extra-vesical ureteral dissection; (3) detrusor division until exposing the mucosa; (4) reimplanting ureter into the new tunnel; and (5) reapproximation and suturing of the detrusor...
January 31, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29427284/a-single-high-dose-of-methamphetamine-reduces-monoamines-and-impairs-egocentric-and-allocentric-learning-and-memory-in-adult-male-rats
#15
Arnold Gutierrez, Michael T Williams, Charles V Vorhees
Methamphetamine (MA) alters dopamine markers and cognitive function in heavy users. In rodents, there are MA dosing regimens that induce concordant effects using repeated administration at spaced intervals. These regimens are effective but complicate experiments designed to disentangle the effects of the drug on different brain regions in relation to their cognitive effects because of treatment spacing. In an effort to simplify the model, we tested whether a single dose of MA could induce the same monoamine and cognitive effects as multiple, spaced dosing without affecting survival...
February 9, 2018: Neurotoxicity Research
https://www.readbyqxmd.com/read/29425453/accelerating-chemical-discovery-with-machine-learning-simulated-evolution-of-spin-crossover-complexes-with-an-artificial-neural-network
#16
Jon Paul Janet, Lydia Chan, Heather J Kulik
Machine learning (ML) has emerged as a powerful complement to simulation for materials discovery by reducing time for evaluation of energies and properties at accuracy competitive with first-principles methods. We use genetic algorithm (GA) optimization to discover unconventional spin-crossover complexes in combination with efficient scoring from an artificial neural network (ANN) that predicts spin-state splitting of inorganic complexes. We explore a compound space of over 5,600 candidate materials derived from eight metal/oxidation state combinations and a 32-ligand pool...
February 9, 2018: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/29422710/developing-foundational-counseling-skills-for-addressing-adherence-issues-in-auditory-rehabilitation
#17
REVIEW
Carole E Johnson, Anna Marie Jilla, Jeffrey L Danhauer
Successfully getting patients with confirmed hearing loss to use hearing aids is a major challenge for hearing health care professionals. Treatment adherence has been defined as the active involvement of patients in collaborating with health care providers to plan and manage treatment regimens. Counseling patients with hearing loss on adherence to recommendations of hearing aid uptake and utilization is dependent upon building a patient-centered therapeutic relationship during the initial diagnostic evaluation...
February 2018: Seminars in Hearing
https://www.readbyqxmd.com/read/29421612/revisit-metaplasticity-the-roles-of-calcineurin-and-histone-deacetylation-in-unlearning-odor-preference-memory-in-rat-pups
#18
Sriya Bhattacharya, Bandhan Mukherjee, Jaqueline Blundell, Carolyn Harley, Qi Yuan
Previous work has shown that 24 h duration odor preference learning, induced by one-trial training, generates a down-regulation of the GluN1 receptor in anterior piriform cortex at 3 h, and results in metaplastic unlearning if a second training trial is given at 3 h. The GluN1 receptor upregulates at 24 h so 24 h spaced training is highly effective in extending memory duration. The present study replicates the piriform cortex unlearning result in the olfactory bulb circuit and further studies the relationship between the initial training strength and its associated metaplastic effect...
February 5, 2018: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/29420556/interactions-between-youth-and-mental-health-professionals-the-youth-aware-of-mental-health-yam-program-experience
#19
Camilla Wasserman, Vita Postuvan, Dana Herta, Miriam Iosue, Peeter Värnik, Vladimir Carli
THE YOUTH AWARE OF MENTAL HEALTH (YAM) EXPERIENCE: Youth stand at the core of much mental health promotion, yet little is written about their experiences of such efforts. We aimed to take this on by interviewing youth after they participated in Youth Aware of Mental Health (YAM), a universal mental health promotion program. YAM has a non-anticipatory methodology that provides youth with a safe space for reflection, role-play, and discussion. Addressing everyday mental health, YAM invites the experiences and issues relevant to the youth present to influence the program in a slightly different direction every time...
2018: PloS One
https://www.readbyqxmd.com/read/29416906/space-brain-the-negative-effects-of-space-exposure-on-the-central-nervous-system
#20
REVIEW
Rahul Jandial, Reid Hoshide, J Dawn Waters, Charles L Limoli
Journey to Mars will be a large milestone for all humankind. Throughout history, we have learned lessons about the health dangers associated with exploratory voyages to expand our frontiers. Travelling through deep space, the final frontier, is planned for the 2030s by NASA. The lessons learned from the adverse health effects of space exposure have been encountered from previous, less-lengthy missions. Prolonged multiyear deep space travel to Mars could be encumbered by significant adverse health effects, which could critically affect the safety of the mission and its voyagers...
2018: Surgical Neurology International
keyword
keyword
83376
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"